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Combined with surgical tool

Subclass of:

623 - Prosthesis (i.e., artificial body members), parts thereof, or aids and accessories therefor

623200100 - HEART VALVE

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DocumentTitleDate
20080275549IMPLANTABLE PROSTHETIC VALVE WITH NON-LAMINAR FLOW - A valve prosthesis device is disclosed suitable for implantation in body ducts. The device comprises a support stent comprised of a deployable construction adapted to be initially crimped in a narrow configuration suitable for catheterization through the body duct to a target location and adapted to be deployed by exerting substantially radial forces from within by means of a deployment device to a deployed state in the target location, and a valve assembly comprising a flexible conduit having an inlet end and an outlet, made of pliant material attached to the support beams providing collapsible slack portions of the conduit at the outlet. The support stent is provided with a plurality of longitudinally rigid support beams of fixed length. When flow is allowed to pass through the valve prosthesis device from the inlet to the outlet the valve assembly is kept in an open position, whereas a reverse flow is prevented as the collapsible slack portions of the valve assembly collapse inwardly providing blockage to the reverse flow. The device is configured so that retrograde flow will be altered from laminar flow and directed towards the leaflets to effect closing. The device can be deployed in a native heart valve position using a deployment catheter advanced through a body lumen such as a blood vessel, including an aorta.11-06-2008
20080269877Systems and methods for valve delivery - A system having an elongate delivery catheter, an elongate mesh body including an expandable region positioned around at least a portion of the elongate delivery catheter, a retractable member that extends through the elongate delivery catheter to connect to the elonga'te mesh body, where the retractable member moves to radially expand the expandable region of the elongate mesh body from an undeployed state to an intermediate state. The system also includes a valve positioned around at least a portion of the elongate delivery catheter position, and a filter positioned around at least a portion of the elongate delivery catheter to filter and control fluid flow.10-30-2008
20120203332APPARATUS AND METHOD FOR DELIVERING AN IMPLANTABLE MEDICAL DEVICE TO A DISEASED CARDIAC VALVE - An apparatus is provided for delivering an implantable medical device to a diseased cardiac valve includes an elongated shank, a brace member, and a locking mechanism. The shank has a first end portion, a second end portion, and a first longitudinal axis extending between the end portions. The first end portion includes a rotatable annular lower support and a fixing member. The lower support includes an annular ring having oppositely disposed upper and lower surfaces and a plane extending radially between the upper and lower surfaces. The brace member includes a barrel portion operably connected to a drive system. The barrel portion includes a first end portion, a second end portion, and a second longitudinal axis extending between the end portions. The drive system includes a housing operably connected to an actuating handle. The locking mechanism is operably connected to the housing and the elongated shank.08-09-2012
20130030520DELIVERY SYSTEMS FOR PROSTHETIC HEART VALVE - Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others.01-31-2013
20130030519DELIVERY SYSTEMS FOR PROSTHETIC HEART VALVE - Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others.01-31-2013
20090192605Sizer Device Having a Plurality of Anterior-Posterior Ratios - Described is a device for evaluating a heart valve annulus in order to choose a particular annuloplasty device to be attached to the annulus, wherein the annuloplasty device has an inter-trigonal or inter-commissural distance and an anterior-posterior ratio, the device comprising: a valve sizing element having one of a plurality of inter-trigonal or inter-commissural distances and comprising a plurality of indicia on the valve sizing element corresponding to a plurality of anterior-posterior ratios and used to compare to the annulus in order to indicate an anterior-posterior ratio of the annulus. Adjustable devices for evaluating a plurality of anterior-posterior ratios are also described. Also, methods of sizing a patient's heart valve annulus are described.07-30-2009
20090192603Adjustable Sizer Devices for Minimally Invasive Cardiac Surgery - Described is an adjustable device for sizing a heart valve annulus by a minimally invasive route, the device comprising: a cannula comprising a proximal end, a distal end and an interior lumen; and at least one wire extending through the interior lumen of the cannula, wherein the at least one wire may be advanced or retracted through the lumen and from the distal end of the cannula, such that a segment of the wire may form a plurality of different predetermined shapes of predetermined sizes used to size the heart valve annulus. Additionally, methods of using such adjustable sizing devices are disclosed.07-30-2009
20110196480POST-OPERATIVE ADJUSTMENT TOOL, MINIMALLY INVASIVE ATTACHMENT APPARATUS, AND ADJUSTABLE TRICUSPID RING - An implantable device system for controlling the dimensions of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implantable devices are disclosed which employ various mechanisms for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the dimensions of the implants after the resumption of normal flow of anatomic fluids in situ.08-11-2011
20110202128Distal Tip Assembly for a Heart Valve Delivery Catheter - A catheter assembly according to the present invention includes a handle assembly, an introducer sheath, and a distal tip assembly. The distal tip assembly can include first and second retaining sleeves and a slotted tip with a non-traumatic tip guard positioned at the proximal end of the slotted tip. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. Each control knob on the handle assembly controls a portion of the components on the distal tip of the catheter by allowing for precise manipulation of various delivery shafts. Each delivery shaft extends from the handle assembly to respective positions towards the distal end of the catheter.08-18-2011
20110202127Apparatus and Methods for Creating a Venous Valve From Autologous Tissue - An implantable prosthesis for percutaneous placement within a vein that forces opposing portions of the vessel wall of a vein together to create a new valve of autologous vein tissue to be operable to alternate between a valve closed configuration and a valve open configuration. When in a preset closed configuration, the implantable prosthesis pushes or pulls portions of the vessel wall of the vein together to substantially close the vein lumen and prevent retrograde blood flow from backflowing through the new valve in the valve closed configuration. The implantable prosthesis has leg portions that may be pushed apart in response to antegrade blood flow through the vein to allow the new valve to achieve the valve open configuration.08-18-2011
20100114306CARDIOVASCULAR PROCEDURES - A method for performing cardiovascular and surgical procedures includes providing a conduit in the form of a graft/canula placed using balloon dilatation catheter and providing a fixing mechanism for the graft/canula. At least one opening is formed through a wall of the heart substantially at the apex. The escape of blood is prevented through the use of the fixing mechanism. Each of these steps is performed while the heart is beating.05-06-2010
20130079872Distal Tip Assembly for a Heart Valve Delivery Catheter - A catheter assembly according to the present invention includes a handle assembly, an introducer sheath, and a distal tip assembly. The distal tip assembly can include first and second retaining sleeves and a slotted tip with a non-traumatic tip guard positioned at the proximal end of the slotted tip. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. Each control knob on the handle assembly controls a portion of the components on the distal by of the catheter by allowing for precise manipulation of various delivery shafts. Each delivery shaft extends from the handle assembly to respective positions towards the distal end of the catheter.03-28-2013
20120209376DEVICE AND METHOD FOR RESHAPING MITRAL VALVE ANNULUS - Methods for treating a defective mitral valve are provided. One preferred method comprises attaching opposing ends of a tether to opposing regions of the mitral valve annulus. The tether is advanced percutaneously into the left atrium by a therapy catheter. Vacuum ports may be provided on the therapy catheter for grasping tissue along the mitral valve annulus. The therapy catheter may also include advanceable needles for passing the tether through the tissue. Alternatively, the ends of the tether may be attached to fastener elements which are secured to the tissue. Tension in the tether pulls the opposing regions of the mitral valve annulus into closer proximity for improving mitral valve function.08-16-2012
20130041459Implant Delivery and Deployment System and Method - An implant delivery system comprising a catheter including at least one lumen, an implant configured for receipt in the lumen, and a latching mechanism configured for receipt in the implant. The latching mechanism may be configured to releasably couple the implant to a delivery wire and to transmit torque through the delivery wire to cause at least a portion of the implant to rotate. The an implant may comprise a shaft, a spacer configured to interact with at least a portion of at least one cusp of a heart valve to at least partially restrict a flow of blood through the heart valve in a closed position, a garage configured to couple the spacer to a first end region of the shaft, and at least one anchor mechanism. The garage may define a cavity to receive the latching mechanism and to increase rotational and translational stability of the latching mechanism.02-14-2013
20100042208Percutaneous Heart Valve - A percutaneously inserted bistable heart valve prosthesis is folded inside a catheter for transseptal delivery to the patient's heart for implantation. The heart valve has an annular ring, a body member having a plurality of legs, each leg connecting at one end to the annular ring, claws that are adjustable from a first position to a second position by application of external force so as to allow ingress of surrounding heart tissue into the claws in the second position, and leaflet membranes connected to the annular ring, the body member and/or the legs, the leaflet membranes having a first position for blocking blood flow therethrough and a second position for allowing blood flow therethrough. The heart valve is designed such that upon removal of the external force the claws elastically revert to the first position so as to grip the heart tissue positioned within the claws, thereby holding the heart valve in place. The body member and claws may be integrated into a one-piece design. The heart valve may be used as a prosthesis for the mitral valve, aortic valve, pulmonary valve, or tricuspid valve by adapting the annular ring to fit in a respective mitral, aortic, pulmonary, or tricuspid valve opening of the heart.02-18-2010
20090157174SYSTEMS AND METHODS FOR ENABLING HEART VALVE REPLACEMENT - The present invention describes a cardiac prosthetic system (06-18-2009
20100030328Apparatus for Treating a Heart Valve, in Particular a Mitral Valve - An apparatus for treating a heart valve apparatus includes at least two anchoring elements designed to be anchored at the annulus and/or heart wall of the valve to be treated. Each anchoring element has a support surface. At least one linking element includes a central branch and two curved side branches, one of which is designed to be engaged on the support surface of an anchoring element, while the other is designed to be engaged on the support surface of another anchoring element, the linking element then being designed to be pivoted to a position such that the anchoring elements interconnect and in which the ends of the central branch are located in the vicinity of the support surfaces.02-04-2010
20100030327DEVICE FOR THE IMPLANTATION OF A THERAPEUTIC OR DIAGNOSTIC APPARATUS IN OR ON A MAMMALIAN INTERNAL ORGAN02-04-2010
20090125102IMPLANTABLE DEVICES FOR CONTROLLING THE INTERNAL CIRCUMFERENCE OF AN ANATOMIC ORIFICE OR LUMEN - An implantable device for controlling the circumference of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implants are disclosed which employ various means for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the circumference of the implants after the resumption of normal flow of anatomic fluids in situ. Methods are disclosed for using the implants to treat heart valve abnormalities, gastroesophageal abnormalities, anal incontinence, and the like.05-14-2009
20120165927Valve with Delayed Leaflet Deployment - A valve for use in a body lumen, where the valve includes a valve leaflet with delayed leaflet deployment relative an in vivo implant time. The valve includes a valve frame, a valve leaflet coupled to the valve frame. The valve leaflet includes a commissure that can reversibly seal for unidirectional flow of a liquid through the valve, and a biodegradable adhesive between the valve leaflet and the valve frame to hold at least the commissure of the valve leaflet in a static relationship relative the valve frame for a predetermined time once implanted in vivo.06-28-2012
20130046376METHOD AND DEVICES FOR FLOW OCCLUSION DURING DEVICE EXCHANGES - A method of reducing the risk of clinical sequelae to catheter induced vascular injuries may include introducing a guide wire into a vascular sheath residing in a blood vessel, proximally retracting the vascular sheath while leaving the wire in place, and observing indicia of the presence or absence of a vascular injury caused to the blood vessel by the vascular sheath or a procedural catheter previously advanced through the vascular sheath. If indicia of a vascular injury are observed, the method may further involve proximally retracting the guide wire to position the inflatable balloon adjacent the injury and inflating the balloon to reduce blood flow past the injury, while leaving the guide wire in place to provide subsequent access to the injury.02-21-2013
20130046377Apparatus for Replacing a Cardiac Valve - A delivery assembly for delivering a prosthetic heart valve can include a first elongate component and a second elongate component. The delivery assembly includes a temporary valve location to which the prosthetic heart valve can be releasably mounted and an implantation location to which the prosthetic heart valve can also be releasably mounted. The delivery assembly can move from a delivery state with the prosthetic heart valve mounted to the temporary location to an implantation state with the prosthetic heart valve repositioned from the temporary location to the implantation location. The prosthetic heart valve can subsequently be deployed from the implantation location. The position of the prosthetic heart valve relative to the first elongate component at the temporary location is different than a position of the prosthetic heart valve relative to the first elongate component at the implantation location.02-21-2013
20110004297TRANSLUMENAL APPARATUS, SYSTEM, AND METHOD - Methods, apparatus, and systems for altering the configuration of a heart valve. Methods, apparatus, and systems include the use of a cord delivered into the heart by a delivery catheter that can be manipulated by a receiving catheter so as to improve the heart valve function.01-06-2011
20130090726RETAINING MECHANISMS FOR PROSTHETIC VALVES - A method of treating a deficient mitral valve without open heart surgery is disclosed. A support band is advanced from a delivery catheter and positioned around native leaflets of the deficient mitral valve. The support band is preferably formed of a shape memory material and is configured to assume a curved shape upon advancement from the delivery catheter. While the support band is positioned around the native leaflets of the mitral valve, an expandable prosthetic heart valve is delivered through an apex of the left ventricle and into the mitral valve. The expandable prosthetic heart valve is then expanded within the mitral valve, thereby causing one or more of the native leaflets of the mitral valve to be frictionally secured between the support band and the prosthetic heart valve.04-11-2013
20090093877ACTIVE HOLDER FOR ANNULOPLASTY RING DELIVERY - An active annuloplasty ring holder having a template that can be folded or pivoted to the side allowing the template to align longitudinally with the handle and enter the patient's chest through a small incision. The holder may include a mechanism to remotely detach sutures fastening the ring to the holder, thereby detaching the ring while avoiding the risk associated with introducing a scalpel into the operating field. A detachment mechanism may include a movable pin actuated by a pull wire that releases a plurality of holding sutures, or a hot wire, knives, or pull wire that severs the sutures. The holder may have a built-in light source for better visualization of the ring inside the heart. The holder may also have an optical means of visualizing the inside of the heart from the proximal end of the handle.04-09-2009
20090093876RECOIL INHIBITOR FOR PROSTHETIC VALVE - A valve loading apparatus is provided for loading a crimped prosthetic valve into a lumen of a delivery system. The valve recoil adapter can counteract recoil of a compressed prosthetic valve, and maintain the valve at its desired crimp diameter. An integrated bioprosthesis/delivery system is provided for delivering a bioprosthesis to a target area within a body lumen is provided. The delivery system includes a valve covering member and a compressing member, which compresses the valve covering member to surround, hold, and/or compress the valve during delivery to the target area.04-09-2009
20130073035Valve Suturing and Implantation Procedures - A prosthesis for implantation at a native semilunar valve includes a prosthetic distal valve, which includes a pliant material configured to collapse inwardly towards a longitudinal axis of the prosthesis during diastole, and to open outwardly during systole, and a distal fixation member configured to be positioned in a downstream artery of the subject. The apparatus also includes a proximal fixation member coupled to the distal fixation member, and configured to be positioned at least partially on a ventricular side of the native semilunar valve. The proximal fixation member is shaped so as to define a lattice that is shaped so as to define an intermediary portion that is coupled to the pliant material of the valve and diverges outwardly from the longitudinal axis, and a distal portion that is distal to the intermediary portion and diverges outwardly from the intermediary portion of the lattice. Other embodiments are also described.03-21-2013
20130073034Leaflet Reinforcement For Regurgitant Valves - A support, and a method for attaching said support, for providing additional strength to existing regurgitant or prolapsed valve leaflets. The support restores an otherwise non-functioning, or poorly functioning, native valve to a functioning condition, obviating the need for a complete valve removal or replacement. The support may also be applied to a functioning valve leaflet as a prophylactic measure against future failure. The delivery method includes a delivery mechanism for attaching the support to the native valve leaflet.03-21-2013
20130073033EXPANDABLE ANNULOPLASTY RING AND ASSOCIATED RING HOLDER - Devices and methods are provided for surgical repair of dilated aortic root to restore aortic valve competence while preserving native leaflets. In one aspect of the invention an expandable annuloplasty ring is provided for external placement at the base of a dilated aortic root. The expandable ring is capable of elastically expanding between a first diastolic diameter and a larger second systolic diameter to provide a physiologically representative surgical repair of the aortic root. In a further aspect of the invention, is provided a holder assembly for aortic annuloplasty ring and suitable for other cardiac valve prosthesis. The holder assembly consists of a holder body pivotingly coupled to a handle member through a ball-and-socket arrangement.03-21-2013
20130073032EXPANDABLE RADIOPAQUE MARKER FOR TRANSCATHETER AORTIC VALVE IMPLANTATION - A delivery device for a collapsible prosthetic heart valve includes a support shaft around which a compartment for the valve is defined, a distal sheath adapted to selectively cover and uncover the compartment and the valve, and a marker cage having a collapsed condition when the distal sheath covers the compartment and an expanded condition when the compartment is uncovered. The marker cage includes at least one rib having a radiopaque marker for determining the positioning of the valve as it is deployed. The valve may be assembled around the marker cage so that the marker cage does not interfere with the radial expansion of the valve during deployment.03-21-2013
20130073031SYSTEMS AND METHODS FOR HOLDING ANNULOPLASTY RINGS - Holders for releasably holding annuloplasty rings prior to and during the implantation of the rings employ any of a variety of features relating to such things as holder shape, handle attachment structures, securement of a ring to the holder, and release of the ring from the holder. In one aspect, the holder includes a flexible bracket and a more rigid connector. In another aspect, the holder includes a flexible bracket and cutting blocks, wherein the interior surface of the cutting block is made of a higher durometer material than the bracket. The interior surface of the cutting block can be coated with a higher durometer material than the material of the bracket. In another aspect, the holder includes a flexible bracket and cutting blocks made of a higher durometer material than the flexible bracket.03-21-2013
20110015730Devices, systems, and methods for reshaping a heart valve annulus, including the use of magnetic tools - Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools.01-20-2011
20110015729TRANSAPICAL DELIVERY SYSTEM FOR HEART VALVES - A delivery system and method for delivering a prosthetic heart valve to the aortic valve annulus. The system includes a delivery catheter having a steering mechanism thereon for delivering a balloon-expandable prosthetic heart valve to the aortic annulus in an antegrade fashion through an introducer passing into the left ventricle through its apex. The introducer may have a more floppy distal section than a proximal section to reduce trauma to the heart wall while preserving good operating field stability. The delivery catheter includes a deflecting segment just proximal to a distal balloon to facilitate positioning of the prosthetic heart valve in the proper orientation within the aortic annulus. A trigger in a catheter handle may be coupled to a deflection wire that actuates the deflecting segment, while a slider in the handle controls retraction of a valve pusher. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized.01-20-2011
20110015727Annuloplasty Ring and Holder Combination - An annuloplasty ring holder includes an angled post for improved visibility and access by the surgeon. The post may be configured to be adjusted in angle and rotation. The ring holder can include a relatively open lower template, including relatively narrow extending radial arms with short, generally arcuate ring-retaining distal portions. The invention includes placements of suture holes and cutting wells which, in combination with improved suture routing, afford the user improved access to cutting the suture that is used to retain the annuloplasty ring to the holder. Another annuloplasty ring and ring holder combination disclosed includes a generally triangular-shaped ring and a generally T-shaped holder. The ring holder has a base portion forming the top of the T shape and engaging against a first segment of the ring, with a radial arm extending from the base portion and forming the post of the T. The radial arm engages against a junction between two segments of the ring.01-20-2011
20130060328Transcatheter Balloon-Assisted Mitral Valve Navigation Device and Method - A method for positioning a centering introducer in a heart of a patient, which includes the steps of inserting an anchoring wire delivery catheter through a heart wall and to a treatment region of the heart, deploying at least one anchoring wire from the delivery catheter and into tissue in the treatment region of the heart, and removing the delivery catheter from the heart. A centering introducer can then be advanced along the anchoring wire to the treatment region, wherein the centering introducer includes an introducer element and at least one balloon. At least one of the balloons can then be inflated to reorient the introducer element in at least one direction relative to a longitudinal axis of the centering introducer.03-07-2013
20090069887FLUID-FILLED DELIVERY SYSTEM FOR IN SITU DEPLOYMENT OF CARDIAC VALVE PROSTHESES - An instrument for deploying a cardiac valve prosthesis, including a plurality of radially expandable portions, at an implantation site, includes a plurality of deployment elements each independently operable to obtain the radial expansion of a radially expandable portion of the valve prosthesis. Additionally, the instrument is adapted to provide a de-aired, fluid-filled, or gas filled environment in order to minimize and/or prevent air embolism during the implantation procedure. The fluid can contain a drug. A method for deploying the cardiac valve prosthesis includes advancing the instrument to an implant site and independently actuating the radially expandable portions.03-12-2009
20100082098DELIVERY DEVICES AND METHODS FOR HEART VALVE REPAIR - Devices, systems and methods facilitate positioning of a cardiac valve annulus treatment device, thus enhancing treatment of the annulus. Methods generally involve advancing an anchor delivery device through vasculature of the patient to a location in the heart for treating the valve annulus, contacting the anchor delivery device with a length of the valve annulus, delivering a plurality of coupled anchors from the anchor delivery device to secure the anchors to the annulus, and drawing the anchors together to circumferentially tighten the valve annulus. Devices generally include an elongate catheter having at least one tensioning member and at least one tensioning actuator for deforming a distal portion of the catheter to help it conform to a valve annulus. The catheter device may be used to navigate a subannular space below a mitral valve to facilitate positioning of an anchor delivery device.04-01-2010
20110022164MEDICAL DEVICE FOR USE IN TREATMENT OF A VALVE - A medical device 01-27-2011
20090234445Catheter device and associated Medical examination and treatment apparatus as well as associated method - A catheter device for treating a cardiac valve disease, which catheter device has a flexible catheter sheath enclosing a catheter cavity and a catheter-specific module disposed at the proximal end close to the catheter tip for the purpose of transporting and positioning a cardiac valve implant and/or for surgically modeling a cardiac valve, is to be embodied in such a way that the risk associated with a cardiac valve intervention is reduced further in comparison with concepts known and practiced in the prior art. Toward that end at least one sensor for imaging is inventively provided in the region of the catheter tip.09-17-2009
20090192601Infundibular Reducer Device Delivery System and Related Methods - Described is a delivery system for minimally invasive delivery of a self-expandable stent to a body lumen, and particularly delivery of a prosthetic valve to the right ventricular outflow tract. Also described is a method of loading a stent onto such a delivery system, and a method of delivering a self-expandable stent to a desired anatomic site.07-30-2009
20130166020SYSTEM FOR LOADING A COLLAPSIBLE HEART VALVE - An assembly for collapsing a self-expanding prosthetic heart valve includes a compression member, a support member, a constricting member, and a spacer which may be used for smaller sized heart valves. The compression member has a tapered wall between its first open end and its second open end, the tapered wall defining an open space adapted to receive the heart valve. The support member has a base and a recess adapted to receive an end of the heart valve. The support member and the compression member are movable toward one another to compress the heart valve and push it through a relatively small aperture in the second open end of the compression member. The second end of the constricting member is sized to receive the compressed heart valve from the second open end of the compression member for loading into a delivery device.06-27-2013
20120271411DEVICES, SYSTEMS AND METHODS FOR ACCURATE POSITIONING OF A PROSTHETIC VALVE - The invention is a system and method for accurately positioning a prosthetic valve such as a prosthetic heart valve at a desired position for deployment. The invention includes extendable positioning elements which provide tactile feedback to a user to confirm proper positioning of the catheter with respect to the native valve annulus. During delivery, the extendable positioning elements lie against the catheter, over the prosthetic valve and expandable balloon, providing a low profile for advancing the catheter to the desired treatment location via small passages such as body lumens. Prior to valve deployment, the positioning elements are extended and brought into contact with tissue of the native annulus to confirm the proper positioning of the delivery system and prosthetic valve.10-25-2012
20100198347DEVICE AND METHOD FOR TREATMENT OF HEART VALVE REGURGITATION - In one embodiment, the present invention provides a prosthesis that can be implanted within a heart to at least partially block gaps that may be present between the two mitral valve leaflets. In one preferred embodiment, the prosthesis includes an anchoring ring that expands within the left atrium to anchor the prosthesis and a pocket member fixed to the anchoring ring. The pocket member is positioned within the mitral valve, between the leaflets so that an open end of the pocket member is positioned within the left ventricle. When the mitral valve is open, blood flows past the pocket member, maintaining the pocket member in a collapsed state. When the mitral valve closes, the backpressure of the blood pushes into the pocket member, expanding the pocket member to an inflated shape. The mitral valve leaflets contact the expanded pocket member, allowing the prosthesis to block at least a portion of the openings between the leaflets, thereby minimizing regurgitated blood flow into the left atrium.08-05-2010
20110082539MINIMALLY INVASIVE AORTIC VALVE REPLACEMENT - A minimally invasive method of implanting a prosthetic aortic valve includes forming a surgical site within a patient's chest that includes a first access port, a second access port, a viewing port and a delivery port. A camera is inserted into the viewing port. The native aortic valve leaflets may each be grasped and removed via tools inserted through the first and second access ports. The prosthetic aortic valve may be delivered through the delivery port to the valve annulus using a delivery device. The prosthetic aortic valve is implanted at the valve annulus and the delivery device is withdrawn. A surgeon may perform the remotely operated steps while viewing images provided by the camera.04-07-2011
20110264203Transcatheter Prosthetic Heart Valve Delivery Device With Passive Trigger Release - A delivery device for percutaneously deploying a prosthetic valve includes a sheath, an inner shaft, and a release assembly. The release assembly is disposed between the sheath and the inner shaft, and includes a retraction member, a release member, and a retention member. The retraction member can self-retract in length from an extended condition to a retracted condition. The release member can self-expand from a compressed condition to an expanded condition. The retention member is distal the release member. In a delivery state, the sheath end is distal the retention member, the release member is in the compressed condition and the retraction member in the extended condition to retain the prosthesis. In a deployment state, the sheath end is positioned to permit the release member to self-transition to the expanded condition, allowing the retraction member to self-transition to the retracted condition and release the prosthesis.10-27-2011
20110282438Valve Introducers And Methods For Making And Using Them - A valve introducer is provided for delivering a valve prosthesis into a biological annulus. During use, a gasket member is introduced into the biological annulus, and secured relative to the biological annulus. A distal end of a valve introducer is introduced into a passage communicating with the biological annulus, and disposed adjacent the gasket member. A valve prosthesis is advanced through the valve introducer towards the gasket member, and secured to the gasket member. In one embodiment, the valve introducer and valve prosthesis have corresponding shapes, requiring the valve prosthesis to be oriented to properly align the valve prosthesis before advancing the valve prosthesis into the valve introducer. Optionally, the valve introducer is manipulated (e.g., by pivoting at a pivot point) to reduce a profile of the distal end before introduction into the passage, which may facilitate introducing the valve introducer through the passage, e.g., past the sino-tubular junction.11-17-2011
20130023983METHOD FOR TREATING AN AORTIC VALVE - Expandable, percutaneously deployable, prosthetic heart valves and systems for minimally invasive replacement of damaged or diseased native aortic valves comprise an expandable, tubular stent body and a unidirectional valve assembly. Embodiments of the stent body comprise an annulus anchoring section, a sinus section, and an outflow section, with the outflow section flared outwardly from the sinus section in an expanded configuration. Embodiments of the stent body are self-expanding, comprising, for example nitinol. The valve assembly disposed within the sinus section of the stent body and sutured thereto. Embodiments of the valve assembly comprise three leaflets, each leaflet comprising a curved outer edge sutured to the sinus section of the stent body, and a coapting free edge. Embodiments of the valve leaflets comprise pericardium, for example, porcine pericardium. Embodiments of the prosthetic heart valve have a contracted configuration dimensioned for percutaneous delivery thereof.01-24-2013
20110112631TRANSAPICAL DELIVERY SYSTEM WITH VENTRUCULO-ARTERIAL OVERLFOW BYPASS - Apparatus is provided for implanting a prosthetic device (05-12-2011
20120290078HEART VALVE DELIVERY SYSTEM WITH VALVE CATHETER - A heart valve delivery system is provided wherein a prosthetic valve is carried on a valve catheter inside a tubular delivery sleeve. The valve catheter has a distal end coupled to a mop. The mop comprises a plurality of flexible extensions configured for releasable attachment to the prosthetic valve. A lead screw nut is coupled to a proximal end of the tubular delivery sleeve and a lead screw is coupled to the valve catheter. The lead screw engages the lead screw nut and rotation of the lead screw causes the delivery sleeve to retract relative to the valve catheter and the prosthetic valve for exposing the prosthetic valve. The flexible extensions of the mop allow expansion of the valve while maintaining the attachment during placement of the valve at a native valve site.11-15-2012
20110301702Transcatheter Delivery System and Method with Controlled Expansion and Contraction of Prosthetic Heart Valve - A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached, includes a shaft assembly including a distal end and a coupling structure disposed near the distal end and configured to be coupled to a distal end of the prosthetic heart valve. The system includes a sheath assembly defining a lumen sized to slidably receive the shaft assembly. The delivery system is configured to transition from a loaded state in which the sheath assembly encompasses the prosthetic heart valve to a deployed state in which the sheath assembly is withdrawn from the prosthetic heart valve. The coupling structure is configured to provide a controlled expansion or contraction of the distal end of the prosthetic heart valve based on longitudinal movement of the distal end of the shaft assembly.12-08-2011
20110301700PERCUTANEOUSLY DELIVERABLE HEART VALVE AND METHODS ASSOCIATED THEREWITH - A prosthetic heart valve implantable by catheter without surgery includes a substantially “dry” membrane or tissue material. In at least one embodiment, the tissue is folded in a dry state to form a tissue leaflet assembly that is then attached to a frame to form an implantable prosthetic heart valve. Alternatively, one or more tissue leaflets are operatively associated with a frame to form an implantable prosthetic heart valve. The implantable prosthetic heart valve is subsequently pre-mounted on an integrated catheter delivery system. The catheter delivery system that includes the implantable prosthetic heart valve is then packaged and transported while the tissue remains dry. The implantable prosthetic heart valve, while remaining substantially dry, can then be implanted into the receiving patient.12-08-2011
20110301701METHOD AND APPARATUS FOR MINIMALLY INVASIVE HEART VALVE PROCEDURES - An apparatus (12-08-2011
20120010699METHOD AND APPARATUS FOR PROSTHETIC VALVE REMOVAL - A method and apparatus for facilitating transapical removal of a prosthetic heart valve, i.e., percutaneously implantable valve (PIV), with-out open-heart surgery. The apparatus includes a holding tool for holding the PIV, a cutting tool for separating the PrV from fibrotic tissue accumulating around the PIV, and a removal tool for extracting the PIV from the heart.01-12-2012
20110295366MOUNTING TOOL FOR LOADING A PROSTHESIS - The present disclosure relates to devices and methods for implanting a prosthesis into a heart of a mammal, such as a person. The disclosure includes a prosthesis that acts as a pressure vent between the left and right atria of the heart. The disclosure also includes a mounting tool for mounting the prosthesis onto a loading tool, the loading tool useful for loading the prosthesis onto a device for delivering the prosthesis into the patient's heart. Control devices and methods for using these devices are also disclosed. The intracardiac pressure vents disclosed allow sufficient flow from the left atrium to the right atrium to relieve elevated left atrial pressure and resulting patient symptoms. The devices also limit the amount of flow from the right atrium to the left atrium to minimize the potential for thrombi or other embolic material from entering arterial circulation.12-01-2011
20120191182PROSTHETIC INSERT FOR TREATING A MITRAL VALVE - A prosthetic insert member for improving the function of a mitral valve is disclosed. The insert member is configured for insertion between leaflets of mitral valve. The insert member has an elongated cross-sectional profile for conforming to the opening in the mitral valve. The device also includes an anchoring member for attachment to heart tissue for maintaining the insert member in the mitral valve. In operation, the insert member fills the opening between the leaflets of the mitral valve and reduces regurgitation while preferably allowing the leaflets to function in a substantially normal manner. In one embodiment, the insert member is formed with a valve member disposed in a passageway for allowing blood to pass through the insert member in one direction.07-26-2012
20110288636SUPPORT DEVICE FOR VALVE PROSTHESES AND CORRESPONDING KIT - A support device for implanting stentless valve prostheses, such as biological heart valves, includes a hub and a plurality of support portions for supporting the stentless valve prosthesis. The hub defines a manipulation axis for the device and is flexibly connected to the support portions to allow displacing the manipulation axis for the device between the support portions.11-24-2011
20110288637Percutaneous Mitral Annular Stitch to Decrease Mitral Regurgitation - This invention relates to methods and devices for treatment of regurgitation by connecting the anterior and posterior mitral annulus with a plurality of stitches or anchors called “mitral annulus bands”, instead of anchoring via the coronary sinus.11-24-2011
20120191181SYSTEMS AND METHODS FOR LOCALIZATION OF A PUNCTURE SITE RELATIVE TO A MAMMALIAN TISSUE OF INTEREST - Systems and methods for localization of a puncture site on an atrial wall relative to a mammalian tissue of interest. In at least one embodiment, such a system includes a bodily access system, having an engagement catheter with an open distal end, a first lumen therethrough, and configured to reversibly attach to a first tissue using suction, a puncture device, configured to fit at least partially within the first lumen, and a scanner configured to identify at least a portion of the bodily access system when positioned within the luminal organ and further configured to identify a distance between a second tissue and a portion of the bodily access system. When such a system is used in connection with a therapeutic procedure, the distance between the second tissue and the portion of the bodily access system is used to facilitate a puncture of the first tissue at a desired location.07-26-2012
20100036483Method and apparatus for improving mitral valve function - A method and apparatus for reducing mitral regurgitation. The apparatus is inserted into the coronary sinus of a patient in the vicinity of the posterior leaflet of the mitral valve, the apparatus being adapted to straighten the natural curvature of at least a portion of the coronary sinus in the vicinity of the posterior leaflet of the mitral valve, whereby to move the posterior annulus anteriorly and thereby improve leaflet coaptation and reduce mitral regurgitation. The apparatus is also configured to work in conjunction with an electrical lead for an implantable bi-ventricular pacing device, an electrical lead for an implantable cardio defibrillator, etc.02-11-2010
20100234940Prosthetic Valve Delivery System - A prosthetic valve delivery system for percutaneously delivering and deploying a prosthetic valve within an existing valve is disclosed. The delivery system includes a stented prosthetic valve having a balloon-expandable stent portion with a prosthetic valve disposed therein and at least one self-expanding stent portion. The delivery system further includes a dual balloon catheter having a first balloon on which the stented prosthetic valve is disposed during delivery and a second balloon. Upon delivery within the existing valve, the self-expanding stent portion contacts the existing valve and the first balloon expands the balloon-expandable stent portion to a first diameter such that the stented prosthetic valve is in a first stage deployment configuration. The second balloon then expands the balloon-expandable stent portion to a second diameter, greater than the first diameter, such that the stented prosthetic valve is in a second stage deployment configuration being fully deployed within the existing valve.09-16-2010
20100121435PERCUTANEOUS TRANSVALVULAR INTRANNULAR BAND FOR MITRAL VALVE REPAIR - Mitral valve prolapse and mitral regurgitation can be treating by implanting in the mitral annulus a transvalvular intraannular band. The band has a first end, a first anchoring portion located proximate the first end, a second end, a second anchoring portion located proximate the second end, and a central portion. The central portion is positioned so that it extends transversely across a coaptive edge formed by the closure of the mitral valve leaflets. The band may be implanted via translumenal access or via thoracotomy.05-13-2010
20120109289Reconfiguring Heart Features - Among other things, a heart tissue support has gripping elements, each element having a free end that is sharp enough to penetrate heart tissue when pushed against the tissue, and a feature to resist withdrawal from the tissue after the sharp free end has penetrated the tissue. Among other things, the shape of a heart valve annulus is corrected in a catheter laboratory by orienting a tip of a catheter holding a heart tissue support that has gripping elements at the valve annulus, applying a radial force from the catheter against the annulus by opening a structure at the tip of the catheter, and while the structure is opened, forcing the support onto the annulus. Among other things, the shape of a heart valve annulus is corrected during a surgical procedure by pushing a heart tissue support that has gripping elements onto the annulus.05-03-2012
20120109288Reconfiguring Heart Features - Among other things, a heart tissue support has gripping elements, each element having a free end that is sharp enough to penetrate heart tissue when pushed against the tissue, and a feature to resist withdrawal from the tissue after the sharp free end has penetrated the tissue. Among other things, the shape of a heart valve annulus is corrected in a catheter laboratory by orienting a tip of a catheter holding a heart tissue support that has gripping elements at the valve annulus, applying a radial force from the catheter against the annulus by opening a structure at the tip of the catheter, and while the structure is opened, forcing the support onto the annulus. Among other things, the shape of a heart valve annulus is corrected during a surgical procedure by pushing a heart tissue support that has gripping elements onto the annulus.05-03-2012
20100100175Adjustable Height Focal Tissue Deflector - A tissue shaping device adapted to reshape target tissue adjacent to a lumen. In some embodiments, the device includes an expandable and contractable anchor, with the anchor having an adjustable height anchoring portion adapted to engage a wall of the lumen in at least first and second anchor heights, the anchoring portion being further adapted to be changed from the first anchor height to the second anchor height by a substantially proximally or a substantially distally directed actuation force. The invention is also a tissue shaping system including a tissue shaping device and a tool for adjusting the height of an anchor of the device. The invention also includes methods of using such tissue shaping devices and systems.04-22-2010
20080281411Assembly Comprising A Ring For Attachment In A Passage Surrounded By Body Tissue As Well As An Applicator For Fitting The Ring In The Passage - The present invention relates to an assembly comprising: a ring having anchoring elements for attaching the ring in a passage surrounded by body tissue, in particular blood vessel tissue. An applicator for fitting the ring in the passage; in which the anchoring elements have an anchoring position in which they protrude with respect to the ring, and in which the anchoring elements comprise a memory material, such as a memory metal or memory polymer, and are designed so that they can be bent from an anchoring position counter to a spring force into a fitting position and can be frozen in this fitting position by a temperature treatment in order to bend the anchoring elements back from the fitting position by the effect of this spring force into the anchoring position when a predetermined threshold temperature is exceeded, and in which the applicator is provided distally with a carrier for carrying the ring. The assembly according to the invention is provided with an influencing system for influencing the temperature of the anchoring elements of the ring carried by the carrier in such a way that the anchoring elements bend back from the fitting position to the anchoring position by increasing the temperature of the anchoring elements to above the threshold temperature.11-13-2008
20080208327METHOD AND APPARATUS FOR REPLACING A PROSTHETIC VALVE - In one aspect, the present disclosure concerns a percutaneously delivered adapter stent that is deployed within a previously implanted prosthetic valve and serves as an anchor or platform for implanting a percutaneously delivered replacement valve within the previously implanted valve. The adapter stent can be delivered to the implantation site via the patient's vasculature and positioned within the previously implanted valve. The stent can then be deployed to cause the stent to expand and become anchored to the inner surface of the previously implanted valve. Subsequently, the replacement valve can be positioned within the adapter stent and deployed to cause the replacement valve to expand and become anchored to the adapter stent. The adapter stent and the replacement valve can be mounted on the same catheter for delivery to the implantation site.08-28-2008
20100100174TOOLS, SYSTEMS, AND METHODS FOR REMODELING TISSUE - A tool for remodeling a tissue annulus includes an elongate handle and a reshaping element on a distal end of the handle. The reshaping element may be directable between a first configuration to facilitate direction through a tissue annulus, and a second curved configuration to remodel tissue adjacent the tissue annulus. The tool may be used for treating a tissue annulus within a patient's heart, e.g., by introducing the reshaping element through the tissue annulus, and manipulating the tool to reshape the tissue annulus substantially to a contour of the reshaping element. The reshaping element may support the tissue while a prosthesis is secured to the tissue annulus, or the reshaping element may itself be secured to the tissue annulus and released from the tool.04-22-2010
20090276038Method and apparatus for tissue connection - A tissue connecting device is provided. The device comprise an elongate delivery device having a lumen, a proximal end, and a distal end. The distal end is configured to engage tissue and advance said device into tissue. At least one anchor deliverable through a lumen of the elongate delivery device. The distal end of the device may be designed to engage tissue upon rotation of the device about its longitudinal axis.11-05-2009
20090276037Method And Apparatus For Circulatory Valve Repair - An apparatus for the repair of a cardiovascular valve has leaflets comprising a grasper capable of grabbing and co-apting the leaflets of the valve. In a preferred embodiment, the grasper has jaws that grasp and immobilize the leaflets, and then a fastener is inserted to co-apt the leaflets. The apparatus is particularly useful for repairing mitral valves to cure mitral regurgitation.11-05-2009
20090281619Low Profile Delivery System for Transcatheter Heart Valve - A heart valve delivery apparatus includes a valve carrying member. A prosthetic valve is crimped onto the valve carrying member at a location that is distal or proximal to the balloon member, thereby providing a smaller profile delivery apparatus.11-12-2009
20100280605DEPLOYMENT TECHNIQUES FOR ANNULOPLASTY RING - An anchor driver is provided that includes a driver head having a flexible ring. An anchor is provided that includes a coupling head, which is shaped so as to define: (a) one or more mating elements that engage mechanical coupling elements of the driver head such that rotation of the mechanical coupling elements rotates the mating elements, which in turn rotate the coupling head, and (b) an outer coupling surface, sized to be inserted into and engage the flexible ring. The anchor also includes a tissue coupling element fixed to the coupling head. The rotation of the mechanical coupling elements causes the tissue coupling element of the anchor to screw itself into tissue, thereby causing separation of: (a) the outer coupling surface of the coupling head from the flexible ring, and (b) the mating elements of the coupling head from the corresponding mechanical coupling elements. Other embodiments are also described.11-04-2010
20110172764Transcorporeal delivery system and method - Transcorporeal delivery system and method for valve replacement surgery that is minimally invasive.07-14-2011
20100121434Medical Devices and Delivery Systems for Delivering Medical Devices - Medical devices and delivery systems for delivering medical devices to a target location within a subject. In some embodiments the medical devices can be locked in a fully deployed and locked configuration. In some embodiments the delivery systems are configured with a single actuator to control the movement of multiple components of the delivery system. In some embodiments the actuator controls the independent and dependent movement of multiple components of the delivery system.05-13-2010
20080249619CARDIAC-VALVE PROSTHESIS - A cardiac-valve prosthesis which can be used, for example, as a valve for percutaneous implantation. The prosthesis includes an armature for anchorage of the valve prosthesis in the implantation site. The armature defines a lumen for passage of the blood flow and supports a set of prosthetic valve leaflets, which, under the action of the blood flow, are able to move into a radially divaricated condition to enable the flow of the blood through the lumen in a first direction and a radially contracted condition, in which the valve leaflets co-operate with one another and block the flow of the blood through the prosthesis in the opposite direction. The armature includes, in one embodiment, two annular elements connected by anchor members having the capacity of projecting radially with respect to the prosthesis, and support members for the set of leaflets, the support members being carried by at least one of the annular elements so as to leave substantially disengaged the aforesaid lumen for passage of the blood.10-09-2008
20110208295IMPLANTABLE DEVICES FOR CONTROLLING THE SIZE AND SHAPE OF AN ANATOMICAL STRUCTURE OR LUMEN - An implantable device system for controlling the dimensions of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implantable devices are disclosed which employ various mechanisms for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the dimensions of the implants after the resumption of normal flow of anatomic fluids in situ.08-25-2011
20080228263Delivery systems and methods of implantation for replacement prosthetic heart valves - A delivery system and method for positioning and partially deploying a replacement valve at an implantation site, verifying the location of the replacement valve relative to the implantation site, and retrieving the partially deployed stent for repositioning relative to the implantation site.09-18-2008
20100280603IMPLANTATION OF REPAIR CHORDS IN THE HEART - A method is provided, including advancing a distal end of an inner shall of a delivery tool between leaflets of an atrioventricular valve, of a patient and into a ventricle of the patient. The method further includes, while maintaining the distal end of the inner shaft in place and within the ventricle, proximally withdrawing a surrounding shaft of the delivery tool with respect to the distal end of the inner shaft and toward the leaflets. This surrounding shaft surrounds a portion of the inner shaft. The method additionally includes using the surrounding shaft to engage at least one of the leaflets with at least one leaflet-engaging element. After engaging, the distal end of the inner shaft is proximally withdrawn from within the ventricle. Other applications are also described.11-04-2010
20090264994APPARATUS AND METHODS FOR TREATING TISSUE - Apparatus and methods are provided for thermally and/or mechanically treating tissue, such as valvular structures, to reconfigure or shrink the tissue in a controlled manner. Mechanical clips are implanted over the leaflets of a valve, e.g., in the heart, either alone or after thermal treatment to cause the valve to close more tightly. The clips are delivered by a catheter and may be configured to traverse directly over the valve itself or to lie partially over the periphery of the valve to prevent obstruction of the valve channel. The clips can be coated with drugs or a radiopaque coating. Alternatively, individual anchors with a tensioning element, like a suture, may be used to approximate the valves towards each other. The catheter can also incorporate sensors or energy delivery devices, e.g., transducers, on its distal end.10-22-2009
20120296417Corkscrew Annuloplasty Device - An annuloplasty device having a plurality of corkscrew anchors is herein disclosed. In some embodiments, the annuloplasty device includes a core wire extending along the length of the device, and at least one corkscrew wire which is operably connected to the corkscrews to screw the corkscrews into heart tissue. In certain embodiments, one or more of the corkscrew wires includes a drive key and the corkscrew anchors are connected to a sleeve with a keyway that engages the drive key on the corkscrew wires. In addition, in some embodiments, the device includes a retractable sheath, which is disposed over the corkscrews to protect them during insertion of the device.11-22-2012
20080200980PROFILE REDUCTION OF VALVE IMPLANT - A method for reducing an axial profile of a valve implant includes providing a valve implant having a longitudinal axis and a delivery catheter having a central axis and a distal receiving section. The method further includes helically rolling the valve implant around a rolling axis that is offset at an angle of about 15 degrees to about 60 degrees with respect to the longitudinal axis to form a rolled valve implant having a rolled axis, where the rolled axis is the same as the rolling axis. The method further includes aligning the rolled axis of the rolled valve implant with the central axis of the delivery catheter. The method further includes inserting the rolled valve implant into the distal receiving section of the delivery catheter.08-21-2008
20080269878MINIMALLY-INVASIVE HEART VALVE WITH CUSP POSITIONERS - A prosthetic heart valve having an internal support frame with a continuous, undulating leaflet frame defined therein. The leaflet frame has three cusp regions positioned at an inflow end intermediate three commissure regions positioned at an outflow end thereof. The leaflet frame may be cloth covered and flexible leaflets attached thereto form occluding surfaces of the valve. The support frame further includes three cusp positioners rigidly fixed with respect to the leaflet frame and located at the outflow end of the support frame intermediate each pair of adjacent commissure regions. The valve is desirably compressible so as to be delivered in a minimally invasive manner through a catheter to the site of implantation. Upon expulsion from catheter, the valve expands into contact with the surrounding native valve annulus and is anchored in place without the use of sutures. In the aortic valve position, the cusp positioners angle outward into contact with the sinus cavities, and compress the native leaflets if they are not excised, or the aortic wall if they are. The support frame may be formed from a flat sheet of Nitinol that is bent into a three-dimensional configuration and heat set. A holder having spring-like arms connected to inflow projections of the valve may be used to deliver, reposition and re-collapse the valve, if necessary.10-30-2008
20080269876Repair of Incompetent Heart Valves by Papillary Muscle Bulking - Incompetency or regurgitation of a cardiac valve is treated by injecting a space occupying material or implanting a space occupying device within a papillary muscle or in heart tissue near a papillary muscle to cause lengthening or repositioning of the papillary muscle in a manner that improves coaptation of the valve leaflets and lessens valvular incompetency or regurgitation. The procedure may be performed by open thoracotomy, thoracoscopically, by a tran-endocardial catheter based approach or by a trans-coronary catheter based approach.10-30-2008
20080234813Percutaneous Interventional Cardiology System for Treating Valvular Disease - A system is provided for treating valvular disease percutaneously though a ventricular apex of the heart. The system includes a needle for piercing through the ventricular apex of the heart and creating a hole whereby a catheter can be passed through the skin and the wall of the heart to gain access to the interior of the heart. Once percutaneous access to the heart is obtained, any of a variety of techniques can be utilized for annular and/or valvular therapy and/or repair through the catheter. A closure device is necessary for closing the puncture of the heart. Any of a variety of vascular closure devices can be modified to be utilized with the system to close the puncture of the ventricular apex of the heart.09-25-2008
20100145439MATERIAL FOR TREATMENT OF A HEART VALVE, IN PARTICULAR A MITRAL VALVE - This material comprises an annuloplasty member (06-10-2010
20110208296Catheter Assembly with Valve Crimping Accessories - Catheter assemblies including a handle assembly located on the proximal end of the catheter assembly and a distal tip assembly located on the distal end of the catheter assembly. A crimping funnel is slidably positioned along the catheter. The crimping funnel includes a distal end having a first diameter and a proximal end having a second diameter smaller than the first diameter. An axial split is formed in the proximal end. A first collar is provided encompassing a portion of the proximal end. The first collar is configured to hold the axial split in the proximal end together when the first collar is at a first axial location along the proximal end, and to allow the axial split in the proximal end to open when the first collar is at a second axial location along the proximal end, such that the crimping funnel can be removed from the catheter assembly. Various methods of retaining a prosthetic valve on the catheter assembly during the crimping process are described.08-25-2011
20090118825METHOD AND APPARATUS FOR IMPROVING MITRAL VALVE FUNCTION - A method and apparatus for reducing mitral regurgitation. The apparatus is inserted into the coronary sinus of a patient in the vicinity of the posterior leaflet of the mitral valve, the apparatus being adapted to straighten the natural curvature of at least a portion of the coronary sinus in the vicinity of the posterior leaflet of the mitral valve, whereby to move the posterior annulus anteriorly and thereby improve leaflet coaptation and reduce mitral regurgitation.05-07-2009
20090138079PROSTHETIC HEART VALVE FOR TRANSFEMORAL DELIVERY - Apparatus is provided that includes a valve prosthesis for attachment to a native valve complex of a subject. The prosthesis includes a support frame, which is shaped so as to define a plurality of axial support arches, which extend in a radially outward direction, and are configured to apply, regardless of a rotational orientation of the support frame with respect to the native valve complex, an upstream axial force to a downstream side of one or more native structures selected from the group consisting of: native leaflet tips of the native valve complex, and native valve commissures. The support frame is also shaped so as to define an upstream skirt, which is configured to apply a downstream axial force on an upstream side of the native valve complex. The prosthesis further includes a prosthetic heart valve, coupled to a portion of the support frame. Other embodiments are also described.05-28-2009
20090259305Implantable Prosthetic Holder and Handle - An improved implantation holder apparatus and system for holding bioprosthetic aortic valves for insertion into a heart. The handle system interacts with implantation holder and the valve in such a way that commissure support struts may be retracted by simply rotating the handle which allows the surgeon more room to work in tight quarters to complete the implantation process. Included is a handle system, which can be attached and detached, for securing the holder during application of the parachute stitching and moving the valve into position. Once the valve is in position, the handle may be retained in place, or removed for greater ease of access to the aortic cavity. Once the valve is fully sutured into place the handle may be easily reattached to the holder with an automatic cutting system to cut the sutures and allow the holder to be more easily and safely be retracted from the aorta.10-15-2009
20090259304Devices and Methods for Treating Valvular Regurgitation - A system for treating mitral valve regurgitation includes a tensioning device having a plurality of helical anchors and a tensioning filament. One embodiment of the invention includes a method for attaching a tensioning device to the annulus of a mitral valve in a trans-leaflet configuration, and applying a tension force to the tension filament in order to exert force vectors on the annulus, thereby reshaping the mitral valve annulus so that the coaption of the anterior and posterior leaflets of the mitral is improved during ventricular contraction.10-15-2009
20080306586Minimally Invasive System for Delivering and Securing an Annular Implant - A delivery device for an annular implant is provided, comprising an annular implant having an adjustable dimension; a plurality of movable elongated deployment members, each having a proximal end and a distal end and an annular implant deployment region therebetween; and a distal joining member for joining the distal ends of the deployment members, wherein the deployment members are expandable by an expansion means to a deployment configuration, and the implant deployment regions of the deployment members are substantially parallel in an expanded configuration. The annular implant can comprise an adjustment mechanism in communication with a releasably attached elongated adjustment tool, whereby the size or shape of the annular implant can be incrementally adjusted.12-11-2008
20110224784MEDICAL DEVICE SUITABLE FOR USE IN TREATMENT OF A VALVE - A medical device (09-15-2011
20090198323Prosthetic Heart Valve System - A prosthetic heart valve system including a prosthetic heart valve and a deflection device. The deflection device includes a line and a connector assembly including a tensioning component. The line interconnects and passes through free ends of stent posts associated with the heart valve, and is further connected to the tensioning component. The tensioning component is transitionable to a tensioning state in which the line is tensioned to inwardly deflect the stent posts. In this regard, the tensioning component is self-locking relative to the line in the tensioning state, and an entirety of the line extending distal the tensioning device does not extend beyond a stent portion of the heart valve opposite the stent posts. In a preferred embodiment, a holder body is further included, coupled to the heart valve apart from the deflection device.08-06-2009
20090198322Methods And Apparatus For Cardiac Valve Repair - The methods, devices, and systems are provided for performing endovascular repair of atrioventricular and other cardiac valves in the heart. Regurgitation of an atrioventricular valve, particularly a mitral valve, can be repaired by modifying a tissue structure selected from the valve leaflets, the valve annulus, the valve chordae, and the papillary muscles. These structures may be modified by suturing, stapling, snaring, or shortening, using interventional tools which are introduced to a heart chamber. Preferably, the tissue structures will be temporarily modified prior to permanent modification. For example, opposed valve leaflets may be temporarily grasped and held into position prior to permanent attachment.08-06-2009
20110144743TREATMENTS FOR A PATIENT WITH CONGESTIVE HEART FAILURE - The invention is directed to two minimally invasive therapeutic procedures, particularly for patients with congestive heart failure, and devices and systems for such procedures. One procedure involves providing a valved passageway through the patient's left ventricular wall at the apex of the patient's heart and advancing instruments through the valved passageway to connect the valve leaflets of the patient's heart valve, e.g. the mitral valve, in a “Bow-Tie” configuration to prevent or minimize regurgitation through the valve. The second procedure involves advancing a pacing lead and a pacing lead implanting device through a trocar in the patient's chest and implanting the pacing lead on an exposed epicardial region of the patient's heart wall. The pacing lead has a penetrating electrode which is secured within the heart wall. One or both procedures may be performed on a patient with CHF.06-16-2011
20110144742Expansion Device for Treatment of Vascular Passageways - A delivery system for delivering an expandable member to a treatment location includes an elongate shaft and an expandable member coupled to a distal end of the elongate shaft. The expandable member is moveable between a collapsed configuration and an expanded configuration, and has an inner expandable member and a plurality of outer expandable members that at least partially surround the inner expandable member.06-16-2011
20090192602Deformable Sizer and Holder Devices for Minimally Invasive Cardiac Surgery - Described is a device for sizing a heart valve annulus by a minimally invasive route, the device comprising: a sizing plate having first and second major surfaces, wherein the sizing plate comprises a deformable material such that the sizing plate can deform and fit through the minimally invasive route; and an elongate handle to which the sizing plate is attached. Also described is a similarly deformable device for holding an annuloplasty device. Additionally, methods of using the deformable sizing and holding devices are disclosed.07-30-2009
20090054976STENT LOADING TOOL AND METHOD FOR USE THEREOF - A loading tool for withdrawing, crimping, and loading a stent-mounted valve into a delivery catheter, and for pushing the stent-mounted valve from the delivery catheter into a native heart valve orifice. The loading tool comprises at least one connector adapted for being removably connected to the stent of the stent-mounted valve. A crimping tool having a generally converging shape is adapted for use with the loading tool. Following connection of the loading tool to the stent-mounted valve, the loading tool operates to allow the stent-mounted valve to be drawn through the crimping tool, and loaded, in a crimped state, into a delivery catheter. Also disclosed is a kit of the of the various components for effecting the delivery of the stent-mounted valve and a method for withdrawing, crimping, and loading a stent-mounted valve from a storage container into a delivery catheter for the performance of a transcatheter valve implantation procedure.02-26-2009
20120078355DEPLOYMENT TECHNIQUES FOR ANNULOPLASTY RING AND OVER-WIRE ROTATION TOOL - Apparatus is provided for use with a subject, including an implant comprising a sleeve shaped so as to define a lumen therein, the sleeve having first and second portions. A contracting mechanism is coupled to a portion of an outer surface of the sleeve in a vicinity of the first portion of the sleeve. An elongated contracting member is coupled at a first end portion thereof to the contracting mechanism, and coupled at a second end portion thereof to the sleeve in a vicinity of the second portion of the sleeve. The contracting mechanism comprises a driving interface that is positioned so as to be accessible from the portion of the outer surface of the sleeve. The contracting mechanism is configured such that rotation of the driving interface contracts the implant by tightening the elongated contracting member. Other applications are also described.03-29-2012
20120078354APPARATUS FOR REPLACING A CARDIAC VALVE - A prosthetic heart valve in combination with a delivery assembly that includes a first elongate component that is movably disposed to a second elongate component. The delivery assembly has a temporary valve location relative to the delivery assembly to which the prosthetic heart valve can be releasably mounted in position and a spaced implantation location relative to the delivery assembly to which the prosthetic heart valve can also be releasably mounted in position. The prosthetic heart valve and delivery assembly combination is configurable with movement of the first elongate component relative to the second elongate component from a delivery state with the prosthetic heart valve mounted in the temporary location to an implantation state with the prosthetic heart valve repositioned from the temporary, location to the implantation location so that the prosthetic heart valve can subsequently be deployed from the implantation location.03-29-2012
20120078353REPLACEMENT HEART VALVES, DELIVERY DEVICES AND METHODS - A replacement heart valve and method of treating valve insufficiency includes an expandable frame configured to engage a native valve annulus. A valve body is coupled to the frame. The valve body can include a leaflet portion and possibly a skirt portion. A portion of the frame has a foreshortening portion configured to longitudinally expand when urged to a radially compacted state and longitudinally contract when urged to a radially expanded state. In one embodiment the valve skirt is attached to the frame so that it can adapt to changes in the length of the frame. A delivery device in some embodiments can use one or more coverings, such as sheaths, to controllably release the replacement heart valve at a native heart valve.03-29-2012
20120078352STAGED DEPLOYMENT DEVICES AND METHODS FOR TRANSCATHETER HEART VALVE DELIVERY SYSTEMS - A delivery device for a collapsible heart valve includes an operating handle, including a frame defining a movement space therein, a carriage assembly moveable within the movement space, and a first resheathing lock having a locked position and an unlocked position. The delivery device further includes a catheter assembly, including a first shaft around which a valve-receiving compartment is defined, the first shaft being fixedly connected to one of the frame or the carriage assembly, and a distal sheath operatively connected to the carriage assembly. The distal sheath is moveable between a closed condition adapted to maintain the valve in the compartment and an open condition adapted to fully deploy the valve. With the resheathing lock in the locked position, the distal sheath is unable to move to the open condition to fully deploy the valve.03-29-2012
20120078351DELIVERY SYSTEM FOR COLLAPSIBLE HEART VALVE - A delivery system for delivering a collapsible prosthetic heart valve includes a valve support structure for supporting a collapsible prosthetic heart valve, and a distal sheath movable in a longitudinal direction relative to the valve support structure between a first position in which the distal sheath is adapted to surround a collapsible prosthetic heart valve supported on the valve support structure, and a second position in which the distal sheath is adapted to expose the collapsible prosthetic heart valve for deployment. The distal sheath is at least partially formed of an inner polymer layer, an outer polymer layer, and a tubular supporting member sandwiched between the inner polymer layer and the outer polymer layer.03-29-2012
20090143857TAPERED LOADING SYSTEM FOR IMPLANTABLE MEDICAL DEVICES - Loading systems for compressing and loading an implantable medical device into a device chamber of a medical device delivery system are described. The loading systems include an elongate holding chamber within which the intraluminal medical device is disposed. A plunger has one or more attached pushers adapted to axially advance the intraluminal medical device through an intermediate portion of the holding chamber that has a tapered surface, which compresses the intraluminal medical device over a dilator of a medical device delivery system that has been introduced through the distal end of the elongate holding chamber. The elongate holding chamber can be placed within an outer storage container with an appropriate seal to for storage of the intraluminal medical device within the loading system. Methods of preparing an intraluminal medical device for implantation in a patient and kits useful in such methods are also described.06-04-2009
20090222082Transcatheter Heart Valve Prostheses - The present teachings relate to a heart valve prosthesis. The heart valve prosthesis includes a docking station (09-03-2009
20090222083MULTI-WINDOW GUIDE TUNNEL - Described herein are devices and methods for delivering implants that comprise multiple coupled anchors. The anchors are secured to tissue using a multi-opening guide tunnel that is configured to releasably retain one or more portions of the implant located between two of the anchors. The releasable retention of one or more intervening portions of the implant maintains the position of the implant and the guide tunnel until the implant is secured to the tissue. The multi-opening guide tunnel permits securement of the multiple anchors without requiring repositioning of the guide tunnel for each anchor.09-03-2009
20120197388COAPTATION ENHANCEMENT IMPLANT, SYSTEM, AND METHOD - Implants, implant systems, and methods for treatment of mitral valve regurgitation and other valve diseases generally include a coaptation assist body which remains within the blood flow path as the leaflets of the valve move, the valve bodies often being relatively thin, elongate (along the blood flow path), and/or conformable structures which extend laterally from commissure to commissure, allowing the native leaflets to engage and seal against the large, opposed surfaces on either side of the valve body during the heart cycle phase when the ventricle contracts to empty that chamber of blood, and allows blood to pass around the valve body so that blood flows from the atrium to the ventricle during the filling phase of the heart cycle. Separate deployment of independent anchors near each of the commissures may facilitate positioning and support of an exemplary triangular valve body, with a third anchor being deployed in the ventricle. An outer surface of the valve body may accommodate tissue ingrowth or endothelialization, while a fluid-absorbing matrix can swell after introduction into the heart. The valve body shape may be selected after an anchor has been deployed, and catheter-based deployment systems may have a desirable low profile.08-02-2012
20090240326Implant Delivery and Deployment System and Method - An implant delivery system comprising a catheter including at least one lumen, an implant configured to be received in the lumen, and a latching mechanism configured to be received in the implant. The latching mechanism may be configured to releasably couple the implant to a delivery wire and to transmit a torque through the delivery wire to cause at least a portion of the implant to rotate. The an implant may comprise a shaft, a spacer configured to interact with at least a portion of at least one cusp of a heart valve to at least partially restrict a flow of blood through the heart valve in a closed position, a garage configured to couple the spacer to a first end region of the shaft, and at least one anchor mechanism. The garage may define a cavity configured to receive the latching mechanism and to increase rotational and translational stability of the latching mechanism.09-24-2009
20090192604Sizer, Holder and Delivery Devices for Minimally Invasive Cardiac Surgery - Described is a device for delivering a valve annulus sizer or annuloplasty device holder to a heart valve annulus, the device comprising: an elongate shaft comprising a proximal end, a distal end and at least a portion of the shaft being malleable, wherein the distal end of the elongate shaft connects to the sizer or holder. Also described are a sizer device for sizing a heart valve annulus, and a delivery device that releasably attaches a sizer device or a holder device for delivery to and/or from a heart valve annulus.07-30-2009
20090192600Sizing device having two sizers and methods of use - A sizing device for measuring a valve annulus, said sizing device comprising: an elongate segment having first and second ends; a first sizer attached to the first end of the elongate segment; and a second sizer attached to the second end of the elongate segment, wherein the first and second sizers have different shapes that correspond to the same size of valve annulus. A method of measuring a valve annulus of a heart. A system for measuring a valve annulus of a heart.07-30-2009
20090254177Method and Apparatuses for Deploying Minimally-Invasive Heart Valves - A system for delivering and deploying a self-expandable heart valve to a site of implantation such as the aortic annulus includes a deployment mechanism that engages the valve and regulates the rate of expansion of both the proximal and distal ends thereof. The heart valve may be a rolled-type valve and the deployment mechanism may include a plurality of distal fingers and a plurality of proximal fingers that engage the outer layer of the head valve. Controlled radial movement of the fingers regulates the unwinding of the rolled heart valve. The fingers may be removed prior to inflation of a balloon to fully expand the valve, or the fingers may be repositioned to the inside of the valve for this purpose. The deployment mechanism may include an umbrella structure that forces the rolled valve outward into its fully expanded configuration. Alternatively, a gear shaft that engages one or more gear tracks on the valve may be utilized to regulate expansion of the valve. A stabilization balloon may be used to axially and radially locate the deployment mechanism relative to the site of implantation. Methods of operation of the delivery and deployment mechanism include regulating the rate of self-expansion of the valve and forcing the valve outward into its fully expanded configuration utilizing the same or different means.10-08-2009
20100152843Percutaneous Methods for Creating Native Tissue Venous Valves - Percutaneous methods of forming a venous valve from autologous tissue are disclosed. The methods include percutaneously creating one or two subintimal dissections for forming one or two flaps of intimal tissue. In one method, a puncture element is delivered by a catheter based delivery system to a treatment site where a new venous valve is to be created. The puncture element is deployed to gain access to a subintimal layer of the vein wall. A dilation balloon is than positioned and inflated within the subintimal layer to create a flap and corresponding pocket/sinus in the vein, which than acts as a one-way monocuspid valve in the manner of a native venous valve. In a similar manner, methods of forming new bicuspid venous valves by subintimal dissections are also disclosed.06-17-2010
20100161043IMPLANTATION OF REPAIR CHORDS IN THE HEART - Apparatus is provided for adjusting at least one dimension of an implant, including a rotatable structure having first and second openings and a channel extending between the first and second openings. The channel allows passage therethrough of an elongate tool. The second end of the structure has a lower surface having one or more recesses along a circumference thereof. A mechanical element provides a protrusion that is disposed within one of the recesses of the rotatable structure during a resting state of the mechanical element, in a manner that restricts rotation of the rotatable structure. The mechanical clement comprises a depressible portion coupled to the protrusion disposed in communication with the second opening of the lower surface, and configured to dislodge the protrusion from within the recess in response to a force applied thereto by the elongate tool. Other applications are also described.06-24-2010
20100161042IMPLANTATION OF REPAIR CHORDS IN THE HEART - A method is provided, including positioning, at an intraventricular site of a ventricle of a patient, a spool coupled to a first end portion of a longitudinal member and coupling a second end portion of the longitudinal member to a portion of tissue facing a lumen of the ventricle. Other embodiments are also described.06-24-2010
20120197389Device and Method for Modifying the Shape of a Body Organ - An intravascular support device includes a support or reshaper wire, a proximal anchor and a distal anchor. The support wire engages a vessel wall to change the shape of tissue adjacent the vessel in which the intravascular support is placed. The anchors and support wire are designed such that the vessel in which the support is placed remains open and can be accessed by other devices if necessary. The device provides a minimal metal surface area to blood flowing within the vessel to limit the creation of thrombosis. The anchors can be locked in place to secure the support within the vessel.08-02-2012
20100185276Devices and Methods for Heart Valve Treatment - Devices and methods for treating heart valves include members that assist the valve in closing during at least a portion of the cardiac cycle. Such devices include members configured to alter the shape of a valve annulus, reposition at least one papillary muscle, and/or plug an orifice of the valve so as to provide a coaptation surface for the valve leaflets.07-22-2010
20100161044Devices, systems, and methods for reshaping a heart valve annulus - Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools.06-24-2010
20100222876APPARATUSES AND METHODS FOR HEART VALVE REPAIR - A medical device for treating a heart having a faulty heart valve is disclosed. The medical device comprises a ligature including a first anchoring member and a second anchoring member is used. The ligature is percutaneously deployable into a patient with a faulty heart valve wherein the first anchoring member to anchor to a first tissue area of the heart and the second anchoring member to anchor to a second tissue area of the heart.09-02-2010
20100217384Method For Replacing Native Valve Function Of A Diseased Aortic Valve - Methods for replacing native valve function of a diseased aortic valve are disclosed. In an embodiment, a method for replacing native valve function of a diseased aortic valve in a patient includes: (a) receiving an artificial heart valve assembly mounted about a first mounting position on a catheter system, (b) guiding the artificial heart valve assembly through the vasculature of the patient, (c) while the catheter system having the artificial heart valve assembly mounted thereto is in the patient's vasculature, mounting the artificial heart valve assembly about a second mounting position on the catheter system, (d) delivering the artificial heart valve assembly to the region of the diseased aortic valve, (e) expanding the artificial heart valve assembly in the region of the diseased aortic valve, and (f) withdrawing the catheter system from the patient's vasculature.08-26-2010
20090076599Heart valve holder assembly for use in valve implantation procedures - A valve holder assembly for delivering a prosthetic heart valve having a stent base an multiple extending commissure posts. The valve holder assembly includes a holder and a rotor that is rotatable relative to the holder.03-19-2009
20090076598Everting Heart Valve - The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve. In some embodiments, the replacement valve is adapted to wrap about the anchor, for example, by everting during endovascular deployment. In some embodiments, the replacement valve is not connected to expandable portions of the anchor. In some embodiments, the anchor is configured for active foreshortening during endovascular deployment. In some embodiments, the anchor includes expandable lip and skirt regions for engaging the patient's heart valve during deployment. In some embodiments, the anchor comprises a braid fabricated from a single strand of wire. In some embodiments, the apparatus includes a lock configured to maintain anchor expansion. The invention also includes methods for endovascularly replacing a patient's heart valve. In some embodiments, the method includes the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve, wrapping at least a portion of the replacement valve about the anchor, and expanding the anchor to a deployed configuration.03-19-2009
20130123913Catheter-Based Annuloplasty System and Method - A catheter-based annuloplasty system for use in repairing a heart valve having leaflets and a valve annulus, includes a delivery catheter having a proximal end and a distal end, and an expandable stent disposed on the distal end of the catheter. An adjustable annuloplasty ring is disposed on the expandable stent and is configured to expand and contract in response to expansion and contraction of the stent.05-16-2013
20130123915DEVICE FOR THE IN SITU DELIVERY OF HEART VALVES - A device for deploying a cardiac valve prosthesis includes a distal valve holder portion and a shaft extending towards the valve holder portion. The shaft is selectively bendable to a curved shape to vary the spatial orientation of the valve holder portion with respect to the desired implantation site.05-16-2013
20110112633DELIVERY/RECOVERY SYSTEM FOR SEPTAL OCCLUDER - A delivery/recovery system to allow an operator to deploy and recover a medical implant, such as an occluder for closing a patent foramen ovale (PFO). In one embodiment, the system includes a delivery mandrel for preventing the occluder from moving in the proximal direction, a delivery wire for securing the occluder to the delivery mandrel and preventing unwanted movement in the distal direction, and a sheath for enveloping the delivery wire, mandrel and occluder. By moving the sheath relative to the occluder in a series of steps, the occluder opens first on a distal side and then on a proximal side, in a manner that holds the occluder in place.05-12-2011
20110112632METHOD OF IMPLANTING A PROSTHETIC VALVE IN A MITRAL VALVE WITH PULMONARY VEIN ANCHORING - A method of implanting a prosthetic mitral valve assembly is disclosed. The prosthetic mitral valve assembly includes a stent and valve combination. The prosthetic mitral valve assembly is provided with an anchoring portion adapted to be positioned in the left atrium. In one embodiment, the anchoring portion includes at least one anchoring arm sized for placement in a pulmonary vein. The stent is radially expandable so that it can expand into position against the walls of the left atrium and accommodate a wide range of anatomies. Contact between the stent and the native tissue in the left atrium reduces paravalvular leakage and prevents migration of the stent once in place.05-12-2011
20120035718DEVICES, SYSTEMS, AND METHODS FOR RESHAPING A HEART VALVE ANNULUS - Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools.02-09-2012
20130218266BALLOON EXPANDABLE PLATFORM WITH RETAINING FEATURES FOR A COLLAPSIBLE VALVE - Retainer structures (08-22-2013
20100137979Sinus-engaging Valve Fixation Member - A prosthesis is provided for implantation at a native semilunar valve of a native valve complex, the native valve complex having three semilunar sinuses and three native commissures. The prosthesis includes a valve prosthesis support, which comprises a support structure comprising exactly three engagement arms that meet one another at three respective junctures. The engagement arms are shaped so as define three peak complexes at the three respective junctures, and three trough complexes, each of which is between two of the peak complexes. Upon implantation of the prosthesis, each of the engagement arms is at least partially disposed within a respective one of the semilunar sinuses, such that each of the peak complexes is disposed distal to and in rotational alignment with a respective one of the native commissures, and each of the trough complexes is disposed at least partially within the respective one of the semilunar sinuses.06-03-2010
20120143319In-Situ Formation of a Valve - The present invention satisfies the long felt need for a more compact and durable valve which may be formed in situ. The present invention provides a self-deployable valve system, a method of delivery, and a method of manufacturing for the self-deployable valve system. The present invention delivers the necessary components for forming a complete valve system in situ. The collapsed subcomponents of the system lack any functional characteristics commonly associated with a valve before being expanded. However, once expanded, the system is transformed into a competent valve for use in a wide variety of applications.06-07-2012
20090319037RETAINING MECHANISMS FOR PROSTHETIC VALVES - Disclosed herein are representative embodiments of methods, apparatus, and systems used to deliver a prosthetic heart valve to a deficient valve. In one embodiment, for instance, a support stent is delivered to a position on the surface of the outflow side of a native heart valve of a patient, the support stent defining a support-stent interior. An expandable prosthetic heart valve is delivered into the native heart valve from the inflow side of the native heart valve and into the support-stent interior. The expandable prosthetic heart valve is expanded while the expandable prosthetic valve is in the support-stent interior and while the support stent is at the position on the surface of the outflow side of the heart valve, thereby causing one or more of the native leaflets of the native heart valve to be frictionally secured between the support stent and the expanded prosthetic heart valve.12-24-2009
20110060405VENOUS VALVE APPARATUS, SYSTEM, AND METHOD - A venous valve apparatus, system and method for valve replacement. The valve includes a valve frame, a valve leaflet joined to the valve frame, and a support frame. The valve leaflet includes surfaces defining a reversibly sealable opening for unidirectional flow of a liquid. The support frame meets the valve frame on an axis, where the valve frame and the support frame extend from the axis in an opposing direction. The system further includes a catheter, where the valve can be reversibly joined to the catheter at a location between a proximal end and a distal end of the catheter. The system can be used to deploy the valve from the catheter at a predetermined location.03-10-2011
20110060404SURGICAL DELIVERY DEVICE AND METHOD OF USE - A delivery device for a stented heart valve comprises a handle, an elongate shaft extending from a distal end of the handle, and a conical housing having a proximal end coupled to the elongate shaft and an open distal end, the conical housing having a conical lumen therein with a first internal diameter adjacent to the proximal end of the conical housing and a larger second internal diameter adjacent to the open distal end of the conical housing.03-10-2011
20100305691Prosthetic Heart Valves, Scaffolding Structures, and Systems and Methods for Implantation of Same - Prosthetic valves and their component parts are described, as are prosthetic valve delivery devices and methods for their use. The prosthetic valves are particularly adapted for use in percutaneous aortic valve replacement procedures. The delivery devices are particularly adapted for use in minimally invasive surgical procedures.12-02-2010
20090069889STREAMLINED, APICAL DELIVERY SYSTEM FOR IN SITU DEPLOYMENT OF CARDIAC VALVE PROSTHESES - A system for implanting a heart valve prosthesis in a patient's heart includes a balloon expandable, tissue, stented heart valve, and an apical valve delivery device for delivering the stented heart valve to a target site in the patient's heart. The delivery device includes an inflation balloon module for expanding the stented heart valve prosthesis, markers on the delivery device to assist in location of the delivery device at an appropriate location, and a streamlined cap.03-12-2009
20090069888Mitral Hook - A mitral hook instrument for use particularly in heart valve operations. The mitral hook is used in particular for grasping or hooking secondary chords for lysis procedures. The interior surface of the hook has a groove or channel to facilitate use of a scalpel to cut a chord or other member which has been grasped and exposed by the hook. Also, markings are preferably provided on the distal end of the mitral hook instrument in order to assist the surgeon.03-12-2009
20090069890STREAMLINED DELIVERY SYSTEM FOR IN SITU DEPLOYMENT OF CARDIAC VALVE PROSTHESES - A system for implanting a heart valve prosthesis in a patient's heart includes a balloon expandable, tissue, stented heart valve and a transfemoral valve delivery device for delivering the stented heart valve to a target site in the patient's heart. The delivery device includes an inflation balloon module for expanding the stented heart valve prosthesis, markers on to assist in location of the delivery device at an appropriate location; and a streamlined cap.03-12-2009
20090069886PROSTHETIC VALVE DELIVERY SYSTEM INCLUDING RETROGRADE/ANTEGRADE APPROACH - A device for implanting an expandable heart valve prosthesis at a valve annulus in a patient's heart includes an implantation device configured to extend from a first opening in the patient's body, through the patient's aorta, through a valve annulus, through an opening in a ventricle, and to exit through the patient's thoracic region. The device further includes a port having a hemostasis valve for providing access through the patient's thoracic region and into the ventricle and at least two interchangeable modules configured for delivery using the implantation device.03-12-2009
20100331972Unitary Quick Connect Prosthetic Heart Valve and Deployment System and Methods - A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable coupling stent, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the coupling stent attached thereto. The coupling stent may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes a hollow two-piece handle through which a balloon catheter passes. A valve holder is stored with the heart valve and the handle easily attaches thereto to improve valve preparation steps.12-30-2010
20100331973Device And Method For Improving The Function Of A Heart Valve - A device for improving the function of a heart valve comprises: a support member formed from a shape memory material, and a restraining member providing a restraining action on a course of the support member. The support member may abut one side of the valve conforming to the shape of the valve annulus upon said shape memory material assuming an activated shape while the restraining member restrains the course of the support member. The restraining action is removable for allowing the support member to assume a desired, altered course. The restraining member may be biodegradable to be degraded within a patient or may be detachable from the support member to be withdrawn. The support member according to another embodiment presents a shape change in that an increased cross-section is associated with a shortened length of the support member. The support member according to yet another embodiment has a first and a second activated shape.12-30-2010
20100331971Cardiac Valve Downsizing Device And Method - A device for repairing a heart valve comprises a medical device (12-30-2010
20090177275SENSING DELIVERY SYSTEM FOR INTRALUMINAL MEDICAL DEVICES - Delivery systems and methods of treatment are described. The delivery systems facilitate visualization, monitoring, or sensing of body vessel parameters, blood parameters, or an intraluminal medical device included in the delivery system prior to, during, or after deployment in a body vessel. A sensing apparatus associated with the delivery systems provide information relating to the body vessel and/or fluid within the body vessel that can be used for verification of placement, confirmation of intraluminal medical device function, and/or determination of the need for additional delivery steps, among other purposes. The information can also be used for verification of initial vessel sizing information.07-09-2009
20110009956MAGNETIC DOCKING SYSTEM AND METHOD FOR THE LONG TERM ADJUSTMENT OF AN IMPLANTABLE DEVICE - An implantable device for controlling the circumference of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implants are disclosed which employ various means for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the circumference of the implants after the resumption of normal flow of anatomic fluids in situ. The invention may include an adjustment tool for making the final adjustments to the circumference that locks onto the adjustment means of the device with magnets. Methods are disclosed for using the implants to treat heart valve abnormalities, gastroesophageal abnormalities, anal incontinence, and the like.01-13-2011
20110015728TRANSAPICAL DELIVERY SYSTEM FOR HEART VALVES - A delivery system and method for delivering a prosthetic heart valve to the aortic valve annulus. The system includes a delivery catheter having a steering mechanism thereon for delivering a balloon-expandable prosthetic heart valve to the aortic annulus in an antegrade fashion through an introducer passing into the left ventricle through its apex. The introducer may have a more floppy distal section than a proximal section to reduce trauma to the heart wall while preserving good operating field stability. The delivery catheter includes a deflecting segment just proximal to a distal balloon to facilitate positioning of the prosthetic heart valve in the proper orientation within the aortic annulus. A trigger in a catheter handle may be coupled to a deflection wire that actuates the deflecting segment, while a slider in the handle controls retraction of a valve pusher. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized.01-20-2011
20110046726Apparatus for Implanting an Aortic Valve Prosthesis - An apparatus for percutaneously implanting an aortic valve prosthesis includes a pump for pumping oxygenated blood from the left atrium into the descending aorta, during a period of time in which an aortic valve prosthesis is being implanted within a diseased aortic valve. First and second catheters are associated with the pump, and a third catheter has an end which is adapted for insertion into the ascending aorta, and the third catheter has an aortic valve prosthesis associated with another end of the third catheter.02-24-2011
20110029071ELONGATED BODY FOR DEPLOYMENT IN A CORONARY SINUS - Coronary sinus ring apparatus, including an elongated body for deployment in a coronary sinus, an aperture in a long side of the body, at least a partial lumen extending from one end of the elongated body to at least the aperture, and a guide within the elongated body positioned and shaped to guide an element inserted along the lumen to the aperture. Apparatus for treating a heart, including a delivery tube sized for and adapted for insertion into a body, a sharp tip adapted to be pushed through cardiac muscle, an elongate tensioning element, and a foldable anchor adapted to couple the elongate tension element to cardiac muscle tissue, wherein the delivery tube encloses one or both of the elongate tensioning element and the foldable anchor. Related apparatus is also described.02-03-2011
20110040374MINIMALLY INVASIVE HEART VALVE REPLACEMENT - A replacement valve for implantation centrally within the orifice of a malfunctioning native heart valve. The valve is designed for minimally invasive entry through an intercostal opening in the chest of a patient and an opening in the apex of the human heart. The replacement valve includes either a separate anchor (02-17-2011
20110245918REPOSITIONABLE ENDOLUMINAL SUPPORT STRUCTURE AND ITS APPLICATIONS - An endoluminal support structure includes strut members interconnected by swivel joints to form a series of linked scissor mechanisms. The structure can be remotely actuated to compress or expand its shape by adjusting the scissor joints within a range of motion. In particular, the support structure can be repositioned within the body lumen or retrieved from the lumen. The support structure can be employed to introduce and support a prosthetic valve within a body lumen.10-06-2011
20110245917Transcatheter Prosthetic Heart Valve Delivery System With Recapturing Feature and Method - A delivery system for percutaneously deploying a stented prosthetic heart valve. The system includes a delivery capsule and a recapture assembly. The capsule is configured to compressively retain the prosthesis. The recapture assembly includes a frame and sleeve attached to the frame. The recapture assembly is transitionable from a compressed arrangement to an expanded arrangement with a distally increasing diameter.10-06-2011
20110213459SYSTEMS AND METHODS FOR TRANSCATHETER AORTIC VALVE TREATMENT - Devices and methods are configured to allow transcervical or subclavian access via the common carotid artery to the native aortic valve, and implantation of a prosthetic aortic valve into the heart. The devices and methods also provide means for embolic protection during such an endovascular aortic valve implantation procedure.09-01-2011
20110087322Method of Treating Aortic Stenosis Using an Implantable Prosthetic Valve - A method of implanting a prosthetic valve in a stenosed aortic valve via a catheterization technique. A balloon catheter is advanced into a patient's vasculature and a balloon is expanded within the stenosed aortic valve to push aside the calcified leaflets. The prosthetic valve is then introduced into a patient's vasculature through an 18 French arterial introducer. After advancement through the femoral artery and aorta, the prosthetic valve is radially expanded for implantation in the dilated aortic valve. The prosthetic valve includes a compressible and expandable frame and a valvular structure made with pericardial tissue. The prosthetic valve further includes an internal cover fastened to an internal surface of the frame between an inlet end of the frame and the valvular structure.04-14-2011
20090099653EXPANDABLE VALVE PROSTHESIS WITH SEALING MECHANISM - A prosthetic heart valve includes at least one sealing member. The sealing member is adapted to conform to any surface irregularities found on the inner surface of the valve annulus, including any calcium deposits formed on the valve leaflets. The sealing member can be self-expanding or non-expanding. When deployed, the sealing member is adapted to create a blood tight seal between the prosthetic heart valve and the inner surface of the valve annulus thereby minimizing and/or eliminating perivalvular leakage at the implantation site.04-16-2009
20100070027IMPLANT IMPLANTATION UNIT AND PROCEDURE FOR IMPLANTING THE UNIT - The implant implantation unit (03-18-2010
20110082538MEDICAL DEVICE, KIT AND METHOD FOR CONSTRICTING TISSUE OR A BODILY ORIFICE, FOR EXAMPLE, A MITRAL VALVE - A device, kit and method may include or employ an implantable device (e.g., annuloplasty implant) and a tool operable to implant such. The implantable device is positionable in a cavity of a bodily organ (e.g., a heart) and operable to constrict a bodily orifice (e.g., a mitral valve). The tissue anchors may be guided into precise position by an intravascularly or percutaneously deployed anchor guide frame of the tool and embedded in an annulus of the orifice. Constriction of the orifice may be accomplished via a variety of structures, for example by cinching a flexible cable or via a anchored annuloplasty ring, the cable or ring attached to the tissue anchors. The annuloplasty ring may be delivered in an unanchored, generally elongated configuration, and implanted in an anchored generally arch, arcuate or annular configuration. Such may approximate the septal and lateral (clinically referred to as anterior and posterior) annulus of the mitral valve, to move the posterior leaflet anteriorly and the anterior leaflet posteriorly, thereby improving leaflet coaptation to eliminate mitral regurgitation.04-07-2011
20110251684DEVICES, SYSTEMS, AND METHODS FOR RESHAPING A HEART VALVE ANNULUS - Implants or systems of implants and methods apply an upward and inward force producing a minor axis force projection vector within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools.10-13-2011
20110251682Transcatheter Prosthetic Heart Valve Delivery System With Funnel Recapturing Feature and Method - A delivery device for percutaneously deploying a stented prosthetic heart valve. The device includes a delivery capsule and a recapture sheath. The capsule is configured to compressively retain the prosthesis. The recapture sheath includes a funnel segment having a plurality of circumferentially spaced runners and a polymer overlay. The runners are attached to a shaft and terminate at a distal tip. The overlay surrounds the runners, and is bonded to the shaft but not to at least the tips. The funnel segment is transitionable from a normal condition to an expanded condition forming a funnel shape with a distally increasing diameter, and self-transitionable back toward the normal condition. The funnel segment facilitates sliding of the capsule over a partially deployed region of the prosthesis as part of a recapturing operation. The runners provide columnar strength, with the overlay controlling a shape of the funnel segment.10-13-2011
20110251681Transcatheter Prosthetic Heart Valve Delivery System with Recapturing Feature and Method - A delivery system for percutaneously deploying a prosthetic heart valve. The system includes an inner shaft assembly, a delivery sheath capsule and a handle maintaining a first actuator and a second actuator. The capsule is configured to compressively retain the prosthetic heart valve over the inner shaft assembly. The first actuator is operated to proximally retract the delivery sheath capsule and expose the prosthetic heart valve relative to the capsule. The second actuator is operated to proximally retract the prosthetic heart valve by transmitting forces to the inner shaft assembly.10-13-2011
20110251680Transcatheter Heart Valve Delivery System With Reduced Area Moment of Inertia - A device for percutaneously repairing a heart valve of a patient including a self-expanding, stented prosthetic heart valve and a delivery system. The delivery system includes delivery sheath slidably receiving an inner shaft forming a coupling structure. A capsule of the delivery sheath includes a distal segment and a proximal segment. An outer diameter of the distal segment is greater than that of the proximal segment. An area moment of inertia of the distal segment can be greater than an area moment of inertia of the proximal segment. Regardless, an axial length of the distal segment is less than the axial length of the prosthesis. In a loaded state, the prosthesis engages the coupling structure and is compressively retained within the capsule. The capsule is unlikely to kink when traversing the patient's vasculature, such as when tracking around the aortic arch, promoting recapturing of the prosthesis.10-13-2011
20110098805TRANSCATHETER VALVE DELIVERY SYSTEMS AND METHODS - Delivery devices and methods for percutaneously delivering a prosthetic valve to the heart of a patient. These prosthetic valves may be configured to provide complimentary features that promote optimal placement of the prosthetic valve in a native heart valve, such as the aortic valve, mitral valve, pulmonic valve, and/or tricuspid valve. The delivery device includes a release sheath assembly housed within an outer delivery sheath. A release sheath component of the assembly captures a portion of the prosthetic valve to the delivery device, and effectuates complete release of the prosthetic valve with retraction of the outer sheath.04-28-2011
20120035717Catheter Assembly with Valve Crimping Accessories - Valve delivery catheter assemblies including components that limit trauma to the expanded prosthetic valve and body channels as the distal tip of the catheter is withdrawn through the expanded valve and thereafter from the body. In one embodiment, a catheter assembly according to the present invention includes a handle assembly, an introducer sheath, and a distal tip assembly. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. A valve retaining mechanism can be included to assist in retaining the prosthetic valve prior to deployment. Each control knob on the handle assembly controls a portion of the components on the distal tip of the catheter by allowing for precise manipulation of various delivery shafts. Each delivery shaft extends from the handle assembly to respective positions towards the distal end of the catheter.02-09-2012
20120303116VALVE PROSTHESIS - The present disclosure relates to valve replacement devices that are foldable for catheter-based deployment to the site of implantation, as well as systems for the delivery of valve prostheses, including prostheses having the special characteristics of the disclosed valve replacement devices. The devices include highly effective adhering mechanisms for secure and enduring precision implantation. The adhering mechanisms may employ a unique sealing mechanism that includes a cuff that expands slowly whereby the device is not secured in place until the completion of the implantation procedure. The implanted device, optionally together with the cuff, prevents perivalvular leaks and incorporate an appropriate leaflet system for reliable functioning in situ.11-29-2012
20120150288PROSTHETIC HEART VALVE PACKAGING AND DEPLOYMENT METHODS - Packaging for prosthetic heart valves including an assembly for securely retaining a heart valve within a jar and facilitating retrieval therefrom. The assembly includes a packaging sleeve that fits closely within the jar and has a clip structure for securing a valve holder. Contrary to previous designs, in one embodiment the valve holder is directed downward into the jar, and the valve is retained with an inflow end upward. The valve may have flexible leaflets, and a leaflet parting member on the end of the shaft extends through the leaflets and couples with the valve holder. The assembly of the packaging sleeve, valve, and holder can then be removed from the jar and a valve delivery tube connected with the holder, or to the leaflet parting member. The packaging sleeve may be bifurcated into two halves connected at a living hinge to facilitate removal from around the valve/holder subassembly.06-14-2012
20100280604OVER-WIRE ROTATION TOOL - Apparatus is provided that includes an implant structure, which includes a contracting mechanism, which includes a rotatable structure, arranged such that rotation of the rotatable structure contracts the implant structure. A longitudinal member is coupled to the contracting mechanism. A tool for rotating the rotatable structure is configured to be guided along the longitudinal member, to engage the rotatable structure, and to rotate the rotatable structure in response to a rotational force applied to the tool. Other embodiments are also described.11-04-2010
20120203334Leaflet Valve - A device and method for improving flow through a native blood vessel valve, such as the aortic valve, are provided. The present invention allows a miniature valve to be implanted into affected leaflets percutaneously, obviating the need for coronary bypass surgery. The method includes the cutting of small holes, on the order of 4 mm, in the leaflets of a targeted valve, thereby allowing blood to flow through the newly formed holes. The holes are used as attachment sites for the miniature valves of the present invention.08-09-2012
20120203333PERCUTANEOUS AORTIC VALVE - A method of minimally invasively replacing a cardiac valve of a patient including inserting a delivery catheter intraluminally, inserting a valve resecting instrument intraluminally through the delivery catheter to a position adjacent the cardiac valve of a patient, manipulating the valve resecting instrument to resect the cardiac valve, removing the resected valve through the delivery catheter, and providing a delivery instrument having a replacement valve contained therein. The delivery instrument is advanced into the delivery catheter and intraluminally so that a distal end portion of the instrument is adjacent an annulus of a patient, and a first portion of the valve is exposed from the delivery instrument to position it on a first side of the annulus, and thereafter a second portion of the valve is exposed to position it on a second side of the annulus.08-09-2012
20100004739TOOLS FOR REMOVAL AND INSTALLATION OF EXCHANGEABLE CARDIOVASCULAR VALVES - Tools for the removal and installation of exchangeable cardiovascular valves. The tools facilitate rapid exchange of a cardiovascular valve member mounted in the aortic position (retrograde exchange) or the mitral position (transapical exchange).01-07-2010
20120203331IMPLANTATION DEVICE - The invention relates to an implantation device (08-09-2012
20120203330METHOD OF POST-OPERATIVE ADJUSTMENT FOR MITRAL VALVE IMPLANT - The present invention is directed to a mechanism and procedure for adjusting a cardiac implant during the early post-operative period, such as, for example, the first 2-5 days after surgery. During the implant procedure, an adjustment tool is releasably attached to the adjustable implant. The adjustment tool remains connected to the implant following the procedure and extends from the patient's body to allow for post-operative adjustment under normal beating heart conditions. Once the implant is adjusted, the adjustment tool is configured to release from the implant and be removed from the patient's body without requiring access to the patient's heart.08-09-2012
20110257737BIOLOGICALLY IMPLANTABLE PROSTHESIS AND METHODS OF USING THE SAME - A heart valve assembly includes a first annular prosthesis for implantation within a tissue annulus, a second valve prosthesis, and a plurality of magnets on the first and second prostheses to secure the second prosthesis to the first prosthesis. In one embodiment, the magnets are arranged to allow the second prosthesis to be secured to the first prosthesis in a predetermined angular orientation. During use, the first annular prosthesis is implanted into the annulus, and the second valve prosthesis is inserted into the annulus. The magnets orient the second prosthesis relative to the first prosthesis to align the second prosthesis with the first prosthesis in a predetermined angular orientation; and secure the second prosthesis to the first prosthesis in the predetermined angular orientation.10-20-2011
20110257736Flexible Heart Valve and Holder Therefor - A highly flexible tissue-type heart valve is disclosed having a structural stent in a generally cylindrical configuration with cusps and commissures that are permitted to move radially. The stent commissures are constructed so that the cusps are pivotably or flexibly coupled together at the commissures to permit relative movement therebetween. The stent may be cloth-covered and may be a single element or may be made in three separate elements for a three cusp valve, each element having a cusp portion and two commissure portions; adjacent commissure portions for each pair of adjacent stent element combining to form the stent commissures. If the stent has separate elements their commissure portions may be pivotably or flexible coupled, or may be designed to completely separate into independent leaflets at bioresorbable couples. The cloth covering may have an outwardly projecting flap that mates with valve leaflets (e.g., pericardial leaflets) along the cusps and commissures. A connecting band may be provided that follows the cusps and commissures and extends outwardly. The valve is connected to the natural tissue along the undulating connecting band using conventional techniques, such as sutures. The connecting band may be a cloth-covered silicon member and attaches to the underside of the valve at the cusps to provide support to the stent and to the outer side of the valve at the commissures. The connecting band includes commissure portions defining generally axial gaps that help permit flexing of the valve.10-20-2011
20110257735SYSTEMS AND METHODS FOR DELIVERING A MEDICAL IMPLANT - The present invention relates to apparatus and methods for endovascularly delivering and releasing a prosthesis, e.g., an aortic prosthesis, within and/or across a patient's native heart valve, referred to hereinafter as replacing the patient's heart valve. In some embodiments the delivery system comprises a plurality of first actuatable element adapted to engage a plurality of second elements in a first configuration to capture the implant within the delivery system, and wherein the plurality of first actuatable element are adapted to engage the plurality of second elements in a second configuration and to release the implant from the delivery system.10-20-2011
20110257734COLLAPSIBLE/ EXPANDABLE PROSTHETIC HEART VALVE DELIVERY SYSTEM AND METHODS - A system for delivering a medical implant includes an expandable member at least partially positioned inside the medical implant and operable to radially expand at least a portion of the medical implant to an expanded condition, first and second grasping mechanisms each adapted to grasp a portion of the medical implant, and a displacement mechanism operatively coupled to the first and second grasping mechanisms and configured to move the first and second grasping mechanisms between an inner position in which the first and second grasping mechanisms are relatively close to one another, and an outer position in which the first and second grasping mechanisms are relatively distant to one another. The movement of the first and second grasping mechanisms from the outer position to the inner position at least partially collapses the medical implant from the expanded condition to enable the medical implant to be repositioned if necessary.10-20-2011
20110054596Method of Delivering a Prosthetic Heart Valve - A method of delivering a prosthetic heart valve to a native valve site within the human vasculature. The prosthetic valve is disposed on a balloon at the end of a balloon catheter. The balloon catheter passes through a delivery sleeve assembly. A pull wire travels from the handle to a distal end of the delivery sleeve assembly. Actuation of the handle pulls on the pull wire, which causes the delivery sleeve assembly to bend for facilitating navigation through a patient's vasculature. A stretchable cover is preferably placed over the slotted tube for biasing the steerable catheter toward a straight position. Once advanced to the vicinity of the native valve site, the prosthetic valve may be accurately positioned by advancing the balloon catheter relative to the delivery sleeve assembly and then deployed within the native valve site by inflating the balloon. In an alternative embodiment, the delivery sleeve assembly may be used to advance a self-expanding prosthetic heart valve through a patient's vasculature and a pusher member may be used to eject the prosthetic valve at the native valve site.03-03-2011
20130158656APPARATUS FOR ENDOVASCULARLY REPLACING A HEART VALVE - An apparatus for endovascular replacement of a heart valve may include first and second members which are releasably attached to each other such that the second member participates in engaging the first member with a locking element which cooperates with the first member to lock an expandable anchor of the replacement heart valve in a deployed configuration. Prior to locking and removal of the second member, the locking element may be prevented from engaging the first member by a portion of the second member. Following locking, the second member may be removed.06-20-2013
20130158655MEDICAL DEVICE HANDLE - A medical device handle may include an elongated handle housing, a rotatable collar disposed about the handle housing, a rotatable control knob disposed about the collar, and a slidable door disposed about the collar. The door may be rotatably locked to the collar to prevent relative rotation between the door and the collar. The door may slidable from a closed position to a first open position, and slidable from the first open position to a second open position.06-20-2013
20110022165INTRODUCER FOR PROSTHETIC HEART VALVE - The present disclosure concerns embodiments of an introducer that is adapted to facilitate insertion of a prosthetic device, such as a prosthetic heart valve, into a patient's vasculature. In one embodiment, the introducer comprises an elongated body defining a central lumen extending between distal and proximal ends of the body. The introducer body can also have a longitudinally extending gap extending along the length of the body between the distal end proximal ends. The gap in the introducer allows a user to place the introducer around implant sutures by passing the sutures through the gap and into the central lumen. Similarly, the gap allows the introducer to be easily removed from the sutures and/or a delivery device by passing them outwardly through the gap.01-27-2011
20110022166MEDICAL DEVICE FOR CONSTRICTING TISSUE OR A BODILY ORIFICE, FOR EXAMPLE A MITRAL VALVE - A medical apparatus positionable in a cavity of a bodily organ (e.g., a heart) may constrict a bodily orifice (e.g., a mitral valve). The medical apparatus may include tissue anchors that are implanted in the annulus of the orifice. The tissue anchors may be guided into position by an intravascularly or percutaneously deployed anchor guiding frame. Constriction of the orifice may be accomplished by cinching a flexible cable attached to implanted tissue anchors. The medical device may be used to approximate the septal and lateral (clinically referred to as anterior and posterior) annulus of the mitral valve in order to move the posterior leaflet anteriorly and the anterior leaflet posteriorly and thereby improve leaflet coaptation and eliminate mitral regurgitation.01-27-2011
20130158654HEART VALVE REPLACEMENT CATHETER - The disclosure pertains to catheter-based delivery system for intravascular heart valve replacement and methods of use thereof. In addition to the replacement heart valve and associated positioning and installation components, the delivery catheter of the system includes a deployable filter element, an actuator for the deployable filter element, and a fluid expandable balloon located proximate the distal end of the delivery catheter. The delivery catheter may be capable of carrying out a valvuloplasty and/or a determination of a distance within a patient.06-20-2013
20130158653MEDICAL DEVICE DELIVERY SYSTEMS - Medical device delivery systems and methods for making and using medical device delivery systems are disclosed. An example medical device delivery system may include an outer sheath. An inner catheter may be disposed within the outer sheath. The inner catheter may have a distal end. A tube extension may be coupled to the distal end of the inner catheter and may extend distally therefrom. The tube extension may be configured to shift between a first elongated configuration and a second shortened configuration.06-20-2013
20110264205EXPANDABLE PROSTHETIC VALVE CRIMPING DEVICE - A device for crimping an implantable device or a part thereof between a radially expanded condition and a radially contracted condition, includes first and second annular bodies arranged about a common axis, and a ring-like array of linear crimping elements having respective opposite ends linked to the first and second annular bodies, respectively. These annular bodies are relatively rotatable around the common axis between a first position, wherein the annular array of crimping elements define a wider orifice for receiving a device to be crimped, and a second position, wherein the annular array of crimping elements define a narrower orifice.10-27-2011
20110264204DEVICES AND METHODS FOR DELIVERING AN ENDOCARDIAL DEVICE - Apical reconstruction and support devices for use in a patient's ventricle include removable implants that may partition the ventricle. Such devices may be implanted using an applicator or system configured for inserting, repositioning and/or removing them. Described herein are applicators, systems, and methods of positioning, deploying and removing cardiac implants. The implants described herein may be inserted into a chamber of a patient's heart, particularly near the apex of the left ventricle, and may support the heart wall. Li some variations the implant is a ventricular partitioning device for partitioning the ventricle into productive and non-productive regions. The applicators may include an expandable member or members at the distal end of a guide to adjustably move the tip of the guide catheter within the ventricle before or during deployment of the implant from the distal end of the guide catheter. These applicators may displace trabeculations within the ventricle.10-27-2011
20110264202Transcatheter Prosthetic Heart Valve Delivery Device with Biased Release Features - A delivery system for percutaneously delivering and deploying a stented prosthetic heart valve. The delivery device includes a delivery sheath slidably disposed over an inner shaft, and a capture assembly. The capture assembly includes a spindle and a biasing member. The spindle is attached to the inner shaft and defines slot. The biasing member is disposed within the slot and self-transitions from a deflected condition to a normal condition. In a delivery state, the delivery sheath retains the prosthesis over the inner shaft and coupled to the spindle via the capture slot, including a portion of the prosthetic valve being engaged within the slot and the biasing member forced to the deflected condition. In a deployment state, the delivery sheath is proximally withdrawn and the biasing member self-transitions toward the normal condition to eject the prosthetic valve from the capture slot.10-27-2011
20110264200Prosthetic Heart Valve Delivery System with Spacing - A device for percutaneously deploying a stented prosthetic heart valve includes a distal portion, a spacing collar, and an outer collar. The distal portion provides a coupling structure configured to selectively engage the stented prosthetic heart valve. The spacing collar is located proximal to the distal portion. The spacing collar is transitionable from a loaded state to an activated state. The spacing collar in the loaded state has a radial dimension less than the spacing collar in the activated state. The outer collar is configured to be movable relative to the distal portion and the spacing collar. The outer collar is slidably disposed over the spacing collar to provide the loaded state and is slidably retracted from the spacing collar when in the activated state.10-27-2011
20110264199Transcatheter Prosthetic Heart Valve Delivery System with Flush Report - A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached includes a shaft assembly including a distal portion and an intermediate portion, and an inner lumen extending through the shaft assembly. The delivery system includes a sheath assembly defining an outer lumen sized to slidably receive the shaft assembly. At least one flush port is formed in the intermediate portion. The at least one flush port is in fluid communication with the inner lumen and the outer lumen. The delivery system is configured to transition from a loaded state in which the sheath assembly encompasses the prosthetic heart valve to a deployed state in which the sheath assembly is withdrawn from the prosthetic heart valve.10-27-2011
20110264198Transcatheter Prosthetic Heart Valve Delivery System and Method with Controlled Expansion of Prosthetic Heart Valve - A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached includes a shaft assembly including a distal end, an intermediate portion, and a first coupling structure disposed near the distal end and configured to be coupled to a distal end of the prosthetic heart valve via a first tether. A sheath assembly defines a lumen sized to slidably receive the shaft assembly. The delivery system is configured to transition from a loaded state in which the sheath assembly encompasses the prosthetic heart valve to a deployed state in which the sheath assembly is withdrawn from the prosthetic heart valve. The first coupling structure is configured to be manipulated in a first direction to provide a controlled expansion or contraction of the distal end of the prosthetic heart valve.10-27-2011
20100292784DEVICE FOR THE IN SITU DELIVERY OF HEART VALVES - A device for deploying a cardiac valve prosthesis includes a distal valve holder portion and a shaft extending towards the valve holder portion. The shaft is selectively bendable to a curved shape to vary the spatial orientation of the valve holder portion with respect to the desired implantation site.11-18-2010
20110118830System For Replacing Native Valve Function Of A Diseased Aortic Valve - Methods for replacing native valve function of a diseased aortic valve are disclosed. In an embodiment, a method for replacing native valve function of a diseased aortic valve in a patient includes: (a) receiving an artificial heart valve assembly mounted about a first mounting position on a catheter system, (b) guiding the artificial heart valve assembly through the vasculature of the patient, (c) while the catheter system having the artificial heart valve assembly mounted thereto is in the patient's vasculature, mounting the artificial heart valve assembly about a second mounting position on the catheter system, (d) delivering the artificial heart valve assembly to the region of the diseased aortic valve, (e) expanding the artificial heart valve assembly in the region of the diseased aortic valve, and (f) withdrawing the catheter system from the patient's vasculature.05-19-2011
20110125256Slitting Tool - A slitting tool can be used to make a linear incision. The slitting can include a flat blade contained within a housing, and an actuator for extending the flat blade out of a housing.05-26-2011
20110137409PROSTHETIC HEART VALVE HAVING FLARED OUTFLOW SECTION - Expandable, percutaneously deployable, prosthetic heart valves and systems for minimally invasive replacement of damaged or diseased native aortic valves comprise an expandable, tubular stent body and a unidirectional valve assembly. Embodiments of the stent body comprise an annulus anchoring section, a sinus section, and an outflow section, with the outflow section flared outward from the sinus section in an expanded configuration. Embodiments of the stent body are self-expanding, comprising, for example nitinol. The valve assembly disposed within the sinus section of the stent body and sutured thereto. Embodiments of the valve assembly comprise three leaflets, each leaflet comprising a curved outer edge sutured to the sinus section of the stent body, and a coapting free edge. Embodiments of the valve leaflets comprise pericardium, for example, porcine pericardium. Embodiments of the prosthetic heart valve have a contracted configuration dimensioned for percutaneous delivery thereof.06-09-2011
20110137408Method and System For Cardiac Valve Delivery - The invention provides methods and systems for introducing a delivery device in the heart at or near the apex of the heart, wherein the delivery device includes a prosthesis, advancing the prosthesis to the target site, and disengaging the prosthesis from the delivery device at the target site for implantation. Specifically, the present invention provides valve replacement systems for delivering a replacement heart valve to a target site in or near a heart. The valve replacement system comprises a trocar or other suitable device to penetrate the heart at or near the apex of the heart, a delivery member that is movably disposed within the trocar, and a replacement cardiac valve disposed on the delivery member. The delivery member may further comprise mechanical or inflatable expanding members to facilitate implantation of the prosthetic valve at the target site.06-09-2011
20100324668Mitral Spacer - A heart valve implant may include a shaft and an anchor configured to be coupled to an end of the shaft. A spacer may be coupled to a portion of the shaft and comprise a plurality of individual segments including a first and at least a second individual segment. The first segment may be coupled to the shaft. The second segment may be coupled to at least a portion of an exterior surface of the first segment and may have at least one cross-section dimension which is greater than an internal cross-sectional dimension of a delivery lumen. Additional segments may be coupled to an inner, adjacent segment. The segments may include a collapsible body portion to facilitate percutaneously delivery through a lumen. The segments may define an outer surface of the spacer configured to interact with at least a portion of at least one cusp of a heart valve to at least partially restrict a flow of blood through the heart valve in a closed position.12-23-2010
20100179648SYSTEM AND METHOD FOR PLACING A PERCUTANEOUS VALVE DEVICE - A system and process for placing a percutaneous valve device in a body lumen at the location of implantation is provided. The placement system and method are simple and enhance the accuracy of the placement of the valve device. Anchors and placement wires or sutures are used to fix the implantation target and guide the device to the implantation site. The system and method are applicable to pre-assembled percutaneous valve devices as well as a modular prosthetic valve device, which modular device is also provided. The modular valve device comprises two or more device modules and is designed to be delivered unassembled and then assembled in the body lumen at or near the site where implantation occurs. The device modules may be assembled before or after the implantation target is fixed with the anchor, and then placed using the placement system in a manner similar to how a pre-assembled percutaneous valve device may be placed in accordance with the invention.07-15-2010
20100179649METHOD AND APPARATUS FOR FINE ADJUSTMENT OF A PERCUTANEOUS VALVE STRUCTURE - The invention provides a device for fine adjustment of a prosthetic valve device and a method of adjusting the position of a prosthetic valve after implantation. The adjustment mechanism includes complementary structures on a valve member and device frame that cooperate to provide relative axial and/or angular motion between the valve member and device frame (and thus the native vessel). The adjustment mechanism of the invention may also include a means for selectively maintaining the relative position of the valve member and device frame. The device and method are particularly applicable for use with a modular prosthetic valve device that is assembled in the body lumen.07-15-2010
20100179647METHODS OF REDUCING EMBOLISM TO CEREBRAL CIRCULATION AS A CONSEQUENCE OF AN INDEX CARDIAC PROCEDURE - There is disclosed a porous emboli deflector for preventing cerebral emboli while maintaining cerebral blood flow during an endovascular or open surgical procedure. The device prevents the entrance of emboli of a size able to cause stroke (such as greater than 100 microns) from entering either the right or left common carotid arteries, and/or the right or left vertebral arteries by deflecting emboli downstream of these vessels. The device can be placed prior to any manipulation of the heart or aorta allowing maximal protection of the brain during the index procedure. The deflector has a low profile within the aorta which allows sheaths, catheters, or wires used in the index procedure to pass. Also disclosed are methods for insertion and removal of the deflector.07-15-2010
20090171456Percutaneous heart valve, system, and method - Devices, systems, and methods are provided to treat diseased cardiac valves. The device includes a percutaneous heart valve having an expandable valve frame including valve frame members, a valve leaflet coupled to the valve frame, and an expandable stent anchoring frame coupled to the valve frame including stent frame members defining a first portion and a second portion having greater flexibility than the first portion, where the first portion and the valve frame define a length, and where the stent frame members and the valve frame members along the length provide a contiguous surface over which a delivery device can repeatedly slide over the length in its entirety in two longitudinal directions when the first portion and the valve frame are in a partially expanded state during delivery from the delivery device.07-02-2009
20100121433RECONFIGURING HEART FEATURES - Among other things, a support for living tissue includes gripping elements to attach to the living tissue and to hold the support securely in place. An annular structure is coupled to the gripping elements. The annular structure adjusts the support between a first configuration for installing the support and a second configuration in which the support is held securely in place after installation. The annular structure is self-supporting in the first and second configurations.05-13-2010
20110178596CARDIAC VALVE LEAFLET ATTACHEMENT DEVICE AND METHODS THEREOF - A medical device system comprising a guide catheter and a leaflet fastening applicator, the guide catheter having suitable dimensions for deployment and insertion percutaneously into a human heart in a vicinity of a heart valve, the leaflet fastening applicator having a size allowing insertion through the guide catheter and being capable of holding portions of opposing heart valve leaflets, wherein the fastening applicator comprises a pair of grasping-electrodes adapted for holding and engaging the portions of opposing heart valve leaflets together and for applying energy to fasten the portions, in which heart valve leaflets can be captured and securely fastened, thereby improving coaptation of the leaflets and improving competence of the valve.07-21-2011
20120310334Prosthetic Valve Delivery System - A prosthetic valve delivery system for percutaneously delivering and deploying a prosthetic valve within an existing valve is disclosed. The delivery system includes a stented prosthetic valve having a balloon-expandable stent portion with a prosthetic valve disposed therein and at least one self-expanding stent portion. The delivery system further includes a dual balloon catheter having a first balloon on which the stented prosthetic valve is disposed during delivery and a second balloon. Upon delivery within the existing valve, the self-expanding stent portion contacts the existing valve and the first balloon expands the balloon-expandable stent portion to a first diameter such that the stented prosthetic valve is in a first stage deployment configuration. The second balloon then expands the balloon-expandable stent portion to a second diameter, greater than the first diameter, such that the stented prosthetic valve is in a second stage deployment configuration being fully deployed within the existing valve.12-06-2012
20120310333SINGLE CATHETER MITRAL VALVE REPAIR DEVICE AND METHOD FOR USE - A single catheter valve repair device for stabilizing a tissue portion and selectively applying a tissue fastener thereto. The single catheter valve repair device of the present invention includes an extendable engagement tip having at least one vacuum port formed thereon, at least one deployable fastener in communication with the engagement tip, and at least one actuator member in communication with the port. The deployable fastener is capable of controllably engaging and fastening a tissue segment located proximal to the engagement tip.12-06-2012
20120310332Delivery Catheter System With Micro and Macro Movement Control - A prosthetic valve delivery system that is improved in controllability by way of a proximal handle system. Such a handle system of the present invention advantageously permits a controlled fine or micro movement or adjustment of a distal sheath for uncovering a plunger that is to be loaded with a prosthetic valve for deployment thereof. The delivery system of the present invention permits a trigger-release for a gross or macro movement to the sheath relative to the plunger. Also, the control handle of the delivery system is shaped and contoured for ease in manipulation of the micro-control actuator.12-06-2012
20120310331METHODS AND APPARATUS FOR ATRIOVENTRICULAR VALVE REPAIR - Methods and devices are disclosed for minimally invasive procedures in the heart. In one application, a catheter is advanced from the left atrium through the mitral valve and along the left ventricular outflow tract to orient and stabilize the catheter and enable a procedure such as a “bow tie” repair of the mitral valve. Right heart procedures are also disclosed.12-06-2012
20120310330PERCUTANEOUS TRANSCATHETER REPAIR OF HEART VALVES VIA TRANS-APICAL ACCESS - Apparatus, systems, and methods are provided for repairing heart valves through percutaneous transcatheter delivery and fixation of annuloplasty rings to heart valves via a trans-apical approach to accessing the heart. A guiding sheath may be introduced into a ventricle of the heart through an access site at an apex of the heart. A distal end of the guiding sheath can be positioned retrograde through the target valve. An annuloplasty ring arranged in a compressed delivery geometry is advanced through the guiding sheath and into a distal portion of the guiding sheath positioned within the atrium of the heart. The distal end of the guiding sheath is retracted, thereby exposing the annuloplasty ring. The annuloplasty ring may be expanded from the delivery geometry to an operable geometry. Anchors on the annuloplasty ring may be deployed to press into and engage tissue of the annulus of the target valve.12-06-2012
20120150287Prosthetic Valve Implantation Systems - Prosthetic valves implantation methods and systems, especially as related to fitting a prosthetic valve at the site of a native stenotic or incompetent valve are described. The subject devices, systems and associated dock deployment and implant docking techniques may be employed in percutaneous valve replacement procedures.06-14-2012
20100191326APPARATUS AND METHOD FOR IMPLANTING COLLAPSIBLE/EXPANDABLE PROSTHETIC HEART VALVES - Apparatus for delivering a prosthetic heart valve into a patient by means that are less invasive than conventional open-chest, open-heart surgery. The prosthetic valve may be collapsed while in a delivery device. When the valve reaches the desired implant site in the patient, the valve can be released from the delivery device, which allows the valve to re-expand to the configuration in which it can function as a heart valve. For example, the delivery device may be constructed to facilitate delivery of the prosthetic valve into the patient via the apex of the patient's heart.07-29-2010
20090292353SYSTEMS AND METHODS TO CONTROL THE DIMENSION OF A HEART VALVE - The cinching apparatus (11-26-2009
20100023117PAPILLARY MUSCLE POSITION CONTROL DEVICES, SYSTEMS, & METHODS - Papillary muscle position control devices (01-28-2010
20100023118METHOD AND APPARATUS FOR REPAIRING OR REPLACING CHORDAE TENDINAE - A method and apparatus for performing mitral valve chordal repair on a patient include attaching at least one filament to a mitral valve leaflet and to a papillary muscle. The length of filaments can be adjusted by adjusting tension in a filament or by altering the effective length of a filament by cutting filament strands or by moving an adjustment member along the length of the filaments.01-28-2010
20110218619LOW-PROFILE HEART VALVE AND DELIVERY SYSTEM - Disclosed replacement heart valves can be designed to be delivered to a native valve site while crimped on a delivery catheter. The crimped profile of the replacement valve can be minimized by, for example, separating a frame or stent structure from a leaflet structure, along the axial direction. Disclosed replacement valves can be transitioned from a delivery configuration, in which the crimped profile can be minimized, to an operating configuration. The replacement valve can be fully assembled in both the delivery and operating configurations. In some embodiments, the leaflets can be positioned outside of the stent in the delivery configuration, and positioned inside of the stent lumen in the operating configuration. Disclosed replacement valves can include a flexible sleeve coupling the leaflets to the stent and facilitating the transition to the operating configuration. Methods of implanting said replacement valves are also disclosed.09-08-2011
20110218621Method Of Replacing Native Heart Valve Tissue - A device for repairing a heart valve comprises an implantation instrument. The implantation instrument comprises a first support ring, and a second support ring connected to said first support ring to form a coiled configuration. The first support ring is configured to abut one side of the valve and the second support ring is configured to abut an opposite side of the valve to thereby trap a portion of the valve tissue therebetween. The device further comprises an annuloplasty implant adapted to be attached to the heart valve annulus in order to reshape the annulus and allow the leaflets to open and close properly. The annuloplasty implant is connected to the implantation instrument for insertion to the annulus.09-08-2011
20110218620Retaining Mechanisms for Prosthetic Valves - Disclosed herein are representative embodiments of methods, apparatus, and systems used to deliver a prosthetic heart valve to a deficient valve. In one embodiment, for instance, a support member is positioned to at least partially surround the native leaflets of a valve. A locking member is used to couple both ends of the support member, forming a support band. An expandable prosthetic heart valve is delivered into the native heart valve and expanded while the expandable prosthetic valve is at least partially within the support band, thereby causing one or more of the native leaflets of the native heart valve to be frictionally secured between the support band and the expanded prosthetic heart valve.09-08-2011
20110118829Attachment device and method - A ventricular assist system and a method of implanting the system are disclosed. The system can have a pump, an inflow conduit, an outflow conduit, and attachment ring and a valvular structure. The attachment ring can be attached to the apex of the heart. The valvular structure can have a flexible, one-way valve in a rigid housing. The inflow conduit can be passed through the valvular structure and the attachment ring into a beating heart with minimal loss of blood.05-19-2011
20120041549REPOSITIONABLE HEART VALVE AND METHOD - A method for percutaneously replacing a heart valve of a patient. In some embodiments the method includes the steps of percutaneously delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; expanding the anchor to a deployed configuration in which the anchor contacts tissue at a first anchor site; repositioning the anchor to a second anchor site; and deploying the anchor at the second anchor site.02-16-2012
20100292782DEVICE FOR THE IN SITU DELIVERY OF HEART VALVES - A device for deploying a cardiac valve prosthesis includes at least one constraint member for radially constraining radially expandable annular portions of the valve. The constraint member is actuatable to release the annular formations constrained thereby and permit radial expansion of these annular formations. The constraint member has associated a first, slow-acting actuating mechanism and a second, fast-acting mechanism, adapted to produce relatively slow and fast release of the annular formations constrained thereby. The device may include a first constraint member and second constraint member in the form of telescoping sleeves. The slow-acting actuating mechanism will thus act on the outer sleeve, while the fast-acting mechanism will act on the inner sleeve to produce, respectively, slow and fast release of the annular formations.11-18-2010
20110307055METHODS AND DEVICES FOR CAPTURING AND FIXING LEAFLETS IN VALVE REPAIR - The present invention provides methods and devices for grasping, and optional repositioning and fixation of the valve leaflets to treat cardiac valve regurgitation, particularly mitral valve regurgitation. Such grasping will typically be atraumatic providing a number of benefits. For example, atraumatic grasping may allow repositioning of the devices relative to the leaflets and repositioning of the leaflets themselves without damage to the leaflets. However, in some cases it may be necessary or desired to include grasping which pierces or otherwise permanently affects the leaflets. In some of these cases, the grasping step includes fixation.12-15-2011
20120041548APPARATUS FOR ATRIOVENTRICULAR VALVE REPAIR - Apparatus for use in repairing an atrioventricular valve in a patient is provided. The apparatus comprises a fastening mechanism for use in repairing a mitral valve in the heart of a patient. The mechanism includes a first end, a second end, and a body extending therebetween. The mechanism is configured to be positioned in the patient's heart using at least one of a guide catheter and an interventional tool that positions the fastening mechanism without penetrating a myocardium. The first end is configured to couple to the valve leaflet while the heart is non-arrested. The second end is configured to couple to a structure other than the valve leaflet, such that the mechanism remains coupled within the heart after being coupled within the heart and simulates the function of a natural chordae.02-16-2012
20110071624DEVICES FOR RETRIEVING A PROSTHESIS - The present disclosure relates to devices and methods for implanting a prosthesis into a heart of a mammal, such as a person. The disclosure includes a prosthesis that acts as a pressure vent between the left and right atria of the heart. The disclosure also includes a mounting tool for mounting the prosthesis onto a loading tool, the loading tool useful for loading the prosthesis onto a device for delivering the prosthesis into the patient's heart. Control devices and methods for using these devices are also disclosed. The intracardiac pressure vents disclosed allow sufficient flow from the left atrium to the right atrium to relieve elevated left atrial pressure and resulting patient symptoms. The devices also limit the amount of flow from the right atrium to the left atrium to minimize the potential for thrombi or other embolic material from entering arterial circulation.03-24-2011
20120046739METHOD OF DELIVERING A MEDICAL DEVICE ACROSS A PLURALITY OF VALVES - Devices and methods for treating veins and venous conditions, such as chronic cerebrospinal venous insufficiency, are provided. In one aspect, the disclosed subject matter provides an intraluminal scaffold having a generally tubular body with a lumen defined therethrough, the tubular body having a compressed condition for delivery and an expanded condition for implant within a vessel having a distended portion, at least a length of the tubular body configured to form an enlarged portion in the expanded condition to engage a wall of the distended portion of the vessel. Methods for fabricating and using the scaffold, methods for remodeling a vein, and methods of deploying a medical device in a vessel without negatively impacting the function of a valve of the vessel, are also provided.02-23-2012
20120046740MEDICAL DEVICES AND DELIVERY SYSTEMS FOR DELIVERING MEDICAL DEVICES - Medical devices and delivery systems for delivering medical devices to a target location within a subject. In some embodiments the medical devices can be locked in a fully deployed and locked configuration. In some embodiments the delivery systems are configured with a single actuator to control the movement of multiple components of the delivery system. In some embodiments the actuator controls the independent and dependent movement of multiple components of the delivery system.02-23-2012
20120209377DEVICES, SYSTEMS, AND METHODS FOR RESHAPING A HEART VALVE ANNULUS, INCLUDING THE USE OF MAGNETIC TOOLS - Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools.08-16-2012
20120209375STABILITY DEVICE FOR USE WITH PERCUTANEOUS DELIVERY SYSTEMS - A delivery system for stabilizing a catheter shaft across an aortic arch can include one or more stabilizing members configured to fix or stabilize the position of the catheter relative to the aortic arch of a patient.08-16-2012
20120065728Stentless Support Structure - A stentless support structure capable of being at least partly assembled in situ. The support structure comprises a braided tube that is very flexible and, when elongated, becomes very long and very small in diameter, thereby being capable of placement within a small diameter catheter. The support structure is preferably constructed of one or more thin strands of a super-elastic or shape memory material such as Nitinol. When released from the catheter, the support structure folds itself into a longitudinally compact configuration. The support structure thus gains significant strength as the number of folds increase. This radial strength obviates the need for a support stent. The support structure may include attachment points for a prosthetic valve.03-15-2012
20090054975DEPLOYMENT DEVICE FOR CARDIAC SURGERY - A deployment device for deploying a material into a patient, said deployment device having a housing and a placement device including a retracted condition within the housing for holding a material, in a collapsed condition, within the housing and an extended condition from the housing for disposing and releasing the material at a predetermined site in an uncollapsed condition. A method of deploying a material by placing the placement device in an extended condition and affixing the material to the extended placement device, retracting the placement device into the housing with the material in a collapsed condition, extending the placement device, and placing the material at a predetermined site in an uncollapsed condition.02-26-2009
20120016469Methods and Apparatus for Endovascularly Replacing a Heart Valve - The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.01-19-2012
20120016471Low Profile Heart Valve and Delivery System - Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: inserting a catheter having a diameter no more than 21 french into the patient; endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve through the catheter; and deploying the anchor and the replacement valve.01-19-2012
20120016470TRANSCATHETER HEART VALVE WITH MICRO-ANCHORS - Various embodiments of methods and apparatus for treating defective heart valve are disclosed herein. In one exemplary embodiment, a transcatheter heart valve is disclosed that includes an expandable shape memory stent and a valve member supported by the stent. A plurality of micro-anchors can be disposed along an outer surface of the stent for engaging native tissue. The transcatheter heart valve can be configured to be advanced into a dilated valve annulus via a balloon catheter. The balloon can be inflated to expand the transcatheter heart valve from a collapsed diameter to an over-expanded diameter such that the micro-anchors engage tissue along the surrounding valve annulus. After engaging the tissue, the balloon can be deflated and the shape memory stent can retract or recoil toward its predetermined recoil diameter. As the stent recoils, the surrounding tissue is pulled inward by the stent such that the diameter of the valve annulus is reduced.01-19-2012
20120016468LOW CROSSING PROFILE DELIVERY CATHETER FOR CARDIOVASCULAR PROSTHETIC IMPLANT - A delivery catheter and a method for deploying a cardiovascular prosthetic implant using a minimally invasive procedure are disclosed. The delivery catheter comprises an elongate, flexible catheter body having a proximal end and a distal end, wherein the distal end has an outer diameter of 01-19-2012
20120022641Valve Holder - Methods and apparatus for holding and maneuvering a valve during preparation and attachment to patient, providing increased visibility of the prosthetic valve and the sewing ring to prevent suture entanglement. A handle attachment is spaced from the valve for improved visibility of the sewing ring and the outlet end of the valve during attachment. Commissure posts are bent inward at the tips while preventing crashing of the commissure posts into each other causing damage. A release force needed to remove the holder and unthread the holder sutures is reduced. The holder and related methods can provide a kink free holder suture path to reduce suture entanglement and prevent damage to the implanted valve during holder removal by reducing the release force needed to remove the holder sutures by up to 30%.01-26-2012
20120022639GUIDE WIRES WITH COMMISSURAL ANCHORS TO ADVANCE A PROSTHETIC VALVE - Apparatus is provided, including one or more valve support guide members configured to be delivered to one or more commissures of a native atrioventricular valve of a patient, one or more valve support anchors configured to be anchored to the one or more commissures of the native valve, a prosthetic valve support advanceable toward the native valve along the one or more valve support guide members and anchored to the native valve at least the one or more commissures, and a prosthetic valve configured to be coupled to the valve support. Other applications are also described.01-26-2012
20120022640TECHNIQUES FOR PERCUTANEOUS MITRAL VALVE REPLACEMENT AND SEALING - Apparatus and methods are described, including one or more valve support guide members that are delivered to one or more commissures of a native atrioventricular valve of a patient. A prosthetic valve support is advanced toward the native valve along the one or more valve support guide members and placed at the native valve. A prosthetic valve is coupled to the valve support. One or more sealing elements facilitate sealing of an interface between the prosthetic valve support and the native valve. Other applications are also described.01-26-2012
20120059457MINIMALLY INVASIVE SURGICAL INSTRUMENT FOR DELIVERY OF CARDIAC DEVICES - A minimally invasive surgical instrument for delivering an external basal annuloplasty device to a heart includes a hollow shaft with a telescopically center tube extending from an end of the hollow shaft. The center tube includes a heart gripping member. A plurality of delivery prongs are slidably coupled to the hollow shaft, each having a distal portion with an expandable wire member for holding the external basal annuloplasty device. A sleeve is telescopically coupled to the expandable wire member. A wire slide is coupled to a proximal portion of the expandable wire member and a sleeve slide is coupled to a proximal portion of the sleeve. The external basal annuloplasty device is mountable on the plurality of delivery prongs by inserting each expandable wire member into a respective pocket on the external basal annuloplasty device.03-08-2012
20110093064HEART VALVE HOLDER FOR USE IN VALVE IMPLANTATION PROCEDURES - A valve holder for a prosthetic valve having a stent with a stent base and multiple commissure posts projecting from the stent base, the valve holder including a central base portion, a plurality of legs radially extending from the central base portion, each leg comprising a first prong portion spaced from a second prong portion by a gap distance, a plurality of commissure post engaging members, wherein one commissure post engaging member is slideably engaged with each of the plurality of legs, and a handle extending from the central base portion.04-21-2011
20110093063Sequential Heart Valve Leaflet Repair Device - A heart valve and tissue repair device for independently, selectively and sequentially grasping heart valve leaflets and independently, selectively and sequentially applying one or more fasteners thereto is disclosed. The device includes a leaflet engaging tip having one or more graspers capable of individually and sequentially grasping leaflets, and one or more deployable fasteners capable of fastening the leaflets. An actuation system for the device individually and selectively controls the graspers and deploys the one or more fasteners. Vacuum pressure from an external vacuum source can be used to grasp the leaflets via a selector system that controls the actuation system so as to individually and sequentially apply vacuum force to the graspers.04-21-2011
20110093062INFLATABLE MINIMALLY INVASIVE SYSTEM FOR DELIVERING AND SECURING AN ANNULAR IMPLANT - A delivery device for an annular implant that includes a balloon expansion mechanism and an annular implant having an adjustable dimension. The balloon expansion mechanism includes an inflation tube attached to a non-occluding balloon collar which is supported by trusses radially extending from a trocar. The annular implant further includes a flexible ring core, contiguous coiled spacers, and anchoring blocks. The flexible ring core is adjusted via a cinching mechanism. The anchoring blocks are spaced along the ring core by the contiguous coiled spacers, which keeps the distance between each pair of anchoring blocks equidistant as the ring core diameter is manipulated by the device user. The annular implant can also include gunbarrel elements housed in the trocar. Each gunbarrel element contains a gunbarrel pusher which drives an attachment element into the annular implant and annular tissue.04-21-2011
20120065729SYSTEMS AND METHODS FOR RAPIDLY DEPLOYING SURGICAL HEART VALVES - A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the frame attached thereto. The frame may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes an integrated handle shaft and balloon catheter. A valve holder is stored with the heart valve and the handle shaft easily attaches thereto to improve valve preparation steps.03-15-2012
20120209374METHODS OF TREATING VALVES - The implant implantation unit (08-16-2012
20120158129SYSTEMS AND METHODS FOR POSITIONING A HEART VALVE USING VISUAL MARKERS - A valve retainer is connected to an elongate delivery member. The valve retainer is configured to releasably secure a prosthesis (e.g., a heart valve prosthesis) to the delivery member during delivery to a target site in a body (e.g., a native valve annulus). The valve retainer includes a rotational identifier that identifies the rotational orientation of the valve retainer when the valve retainer is positioned proximate to the target site. A heart valve prosthesis can include a commissural post that has a predetermined rotational position relative to the rotational identifier, such that the heart valve prosthesis can be rotationally aligned with the native commissures of the native valve by rotating the delivery member and the valve retainer until the commissural post is aligned with a native valve commissure and the rotational identifier is visible.06-21-2012
20120158128PROSTHETIC HEART VALVE DELIVERY SYSTEMS AND PACKAGING - Packaging for dry prosthetic tissue heart valves and their delivery systems includes a primary sterile barrier that permits gas sterilization of the tissue implant, and a secondary sterile barrier that also prevents oxidation of the implant during long-term storage. Dry tissue heart valves and their delivery systems are placed within a primary container such as a rigid tray that limits movement of the components therein. The primary container is placed within a secondary container, and the assembly is then sterilized. The outer sterile barrier may include a double seal so that a first gas-permeable seal can be closed for sterilization, after which a second gas-impermeable seal can be closed to seal out any further oxygen contact with the tissue implant. A collapsible delivery handle for a surgical heart valve may be provided which reduces the size of the packaging.06-21-2012
20120071968ROBOTIC HEART VALVE ANNULUS SIZER - A heart valve annulus sizer is provided for measuring a valve to be fitted with an annuloplasty ring. The sizer may include a body having a peripheral portion defining an opening, at least one rib disposed within the opening and dividing the opening into at least a first opening and a second opening, and an anchor disposed on and projecting from the body. The sizer may include a length of suture connected to the body. The anchor may include an aperture adapted to receive the length of suture. A method of using the sizer is provided that includes grasping the sizer with an instrument and positioning the sizer adjacent to a valve into a position suitable to allow for measurement of the valve.03-22-2012
20110071623METHODS FOR DEPLOYING A PROSTHESIS - The present disclosure relates to devices and methods for implanting a prosthesis into a heart of a mammal, such as a person. The disclosure includes a prosthesis that acts as a pressure vent between the left and right atria of the heart. The disclosure also includes a mounting tool for mounting the prosthesis onto a loading tool, the loading tool useful for loading the prosthesis onto a device for delivering the prosthesis into the patient's heart. Control devices and methods for using these devices are also disclosed. The intracardiac pressure vents disclosed allow sufficient flow from the left atrium to the right atrium to relieve elevated left atrial pressure and resulting patient symptoms. The devices also limit the amount of flow from the right atrium to the left atrium to minimize the potential for thrombi or other embolic material from entering arterial circulation.03-24-2011
20110066234Percutaneous Mitral Valve Annuloplasty Delivery System - The invention is a tissue shaping system, including a tissue shaping device with an expandable anchor and a lock; a delivery catheter; a delivery mechanism adapted to deliver the tissue shaping device from outside a patient to a target site within a lumen within the patient via the delivery catheter; and an actuator adapted to deliver an actuation force to the lock to lock the anchor in an expanded configuration. The invention is also a system adapted to percutaneously deliver and deploy a tissue shaping device at a target site within a lumen of a patient. The system includes: a handle; a delivery mechanism supported by the handle and adapted to deliver the tissue shaping device from outside the patient to the treatment site via a delivery catheter; and an actuator supported by the handle and adapted to deliver an actuation force to lock an anchor of the tissue shaping device in an expanded configuration.03-17-2011
20110066233METHODS, SYSTEMS AND DEVICES FOR CARDIAC VALVE REPAIR - Disclosed are devices and methods for treating regurgitation through a valve in the heart. The devices can include an expandable, fluid-tight bladder configured to be deployed between valve leaflets of the heart valve. The bladder can include an upper portion that extends into the atrium of the heart; a lower portion that extends into the ventricle of the heart; and a middle portion positionable within the line of valve leaflet coaptation that provides a sealing surface for one or more of the leaflets.03-17-2011
20110066232BIOPROSTHETIC VALVE HOLDER AND HANDLE WITH CUTTING MECHANISM AND METHOD OF USING SAME - A surgical apparatus for use with a prosthetic holder to which a prosthesis is secured by sutures. The apparatus includes an elongated handle having a grip end and a coupler end and defining a first aperture extending along a length from the grip end to the coupler end. The apparatus can also include a first shaft at least partially disposed within the first aperture with a first actuator at the grip end and a holder coupling mechanism at the coupler end. The apparatus can have one of a second shaft and a sheath disposed along the handle with a second actuator at the grip end and a cutting element at the coupler end. A force applied to the first actuator enables one of engagement and disengagement with the prosthesis holder, and a force applied to the second actuator enables deployment of a cutting element to cut the sutures securing the prosthesis to the prosthetic holder.03-17-2011
20110066231IMPLANTABLE DEVICES FOR CONTROLLING THE SIZE AND SHAPE OF AN ANATOMICAL STRUCTURE OR LUMEN - An implantable device system for controlling the dimensions of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implantable devices are disclosed which employ various mechanisms for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the dimensions of the implants after the resumption of normal flow of anatomic fluids in situ.03-17-2011
20110106246TRANSAPICAL DELIVERY DEVICE AND METHOD OF USE - A delivery device for a stented heart valve comprises a handle, an inner catheter shaft extending from the handle and having an enlarged bumper element at a distal end, an outer catheter shaft extending from the handle and slidably coupled around the inner catheter shaft, and a retraction mechanism for controlling longitudinal movement of the outer catheter shaft relative to the inner catheter shaft. The outer catheter shaft includes a generally cylindrical housing at a distal end that is structured to receive the bumper element therein.05-05-2011
20110106245APPARATUS FOR GUIDE-WIRE BASED ADVANCEMENT OF A ROTATION ASSEMBLY - Apparatus is provided for use with at least one tissue-adjustment device, including a tissue-engaging element having a distal portion configured to engage at least a first portion of tissue of a patient, and having a proximal portion. At least one docking station is coupled to the proximal portion of the tissue-engaging element and is configured to be coupled to the at least one tissue-adjustment device. The docking station includes a locking mechanism configured to lock the tissue-adjustment device to the tissue-engaging element. At least one guide member is reversibly coupled to the at least one docking station and is configured for facilitating slidable advancement of the at least one tissue-adjustment device toward the tissue-engaging element. Other applications are also described.05-05-2011
20120123529PROSTHETIC HEART VALVE - Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. A valve frame can have a tapered profile when mounted on a delivery shaft, with an inflow end portion having a smaller diameter than an outflow end portion. The valve can comprise generally V-shaped leaflets, reducing material within the inflow end of the frame. An outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack when the valve is expanded and lying flat against the frame when the valve is collapsed. A diagonally woven inner skirt can elongate axially with the frame. Side tabs of adjacent leaflets can extend through and be secured to window frame portions of the frame to form commissures. The window frame portions can be depressed radially inward relative to surrounding frame portions when the valve is crimped onto a delivery shaft.05-17-2012
20090132034Bioprosthetic Valve Clip and Handle - An improved implantation holder apparatus and system for holding bioprosthetic aortic valves for insertion into a heart. The handle system interacts with implantation holder and the valve in such a way that commissure support struts may be retracted by simply rotating the handle which allows the surgeon more room to work in tight quarters to complete the implantation process. Included is a handle system, which can be attached and detached, for securing the holder during application of the parachute stitching and moving the valve into position. Once the valve is in position, the handle may be retained in place, or removed for greater ease of access to the aortic cavity.05-21-2009
20090132033Implant Delivery System and Method - An implant delivery system may comprise a catheter including at least one lumen, a guide wire configured to be received in the lumen, and an implant. The guide wire may comprise a clamping mechanism disposed about a distal end of the guide wire. The clamping mechanism may include a first and at least a second jaw wherein at least one of the jaws is configured to pivot between a closed position wherein the jaws define at least one internal cavity between the jaws configured to receive at least a portion of the implant and an open position configured to release the implant. The implant may be configured to be received in the lumen and may comprise a driver configured to be releasably received in the cavity of the clamping mechanism.05-21-2009
20120123528STAGED DEPLOYMENT DEVICES AND METHOD FOR TRANSCATHETER HEART VALVE DELIVERY - A delivery device for a collapsible heart valve includes an operating handle and a catheter assembly. The operating handle includes a frame defining a movement space therein, a carriage assembly moveable in a longitudinal direction within the movement space, and a coupler having locked and unlocked conditions, the coupler being operatively connected to the carriage assembly for movement therewith. The catheter assembly includes a shaft around which a valve-receiving compartment is defined, the shaft being operatively connected to one of the frame or the carriage assembly, and a distal sheath operatively connected to the carriage assembly for movement therewith between a closed condition adapted to maintain the valve in the compartment and an open condition adapted to fully deploy the valve.05-17-2012
20100249920RECONFIGURING HEART FEATURES - Among other things, a heart tissue support has a ring-shaped body and gripping elements, each gripping element having a free end that is sharp enough to penetrate heart tissue when pushed against the tissue, and a feature to resist withdrawal of the gripping element from the tissue after the sharp free end has penetrated the tissue. Among other things, a tool to attach a support to a heart valve annulus has splaying elements that spread apart to hold the support in an expanded configuration prior to attachment. Among other things, an apparatus includes polygonal elements connected along corners of the elements to form a ring, the polygonal elements being capable of expanding and contracting, and gripping elements attached to points of the polygonal elements. Among other things, a method includes using a delivery tool to expand a support and a heart valve annulus to one diameter.09-30-2010
20100249921Cardiac Valve Procedure Methods and Devices - Devices and methods for performing intravascular procedures without cardiac bypass include embodiments of temporary filter devices, temporary valves, and prosthetic valves. The temporary filter devices have a cannula which provides access for surgical tools for effecting repair of cardiac valves. The cannula may have filters which prevent embolitic material from entering the coronary arteries and aorta. The valve devices may also have a cannula for insertion of the valve into the aorta. The valve devices expand in the aorta to occupy the entire flow path of the vessel and operate to prevent blood flow and to permit flow through the valve. The prosthetic valves include valve fixation devices which secure the prosthetic valve to the wall of the vessel. The prosthetic valves are introduced into the vascular system in a compressed state, advanced to the site of implantation, and expanded and secured to the vessel wall.09-30-2010
20100249918DEVICES AND METHODS FOR DELIVERY OF AORTIC AND MITRAL VALVE PROSTHESES - A valve prosthesis and implantation device, and methods for use are provided. The devices described herein may be used for transcatheter delivery of an aortic valve prosthesis or transapical delivery of a mitral valve prosthesis. The implantation device utilizes movable claspers for both positioning and anchoring the valve prosthesis, reducing the extent of imaging needed during the implantation procedure.09-30-2010
20100249919PRE-SIZED PROSTHETIC CHORDAE IMPLANTATION SYSTEM - A pre-sized prosthetic chordae assembly includes a male attachment unit and a female securing member. The male attachment unit includes a plurality of pre-sized prosthetic chordae fixedly connected to at least one male attachment member and a papillary muscle penetration member that is connected to and extends substantially axial to the at least one male attachment member. The female securing member is for receiving the papillary penetration member.09-30-2010
20100249917Methods for Delivery of a Sutureless Pulmonary or Mitral Valve - Methods for delivering a sutureless pulmonary or mitral valve prosthesis using a transcatheter approach are provided. The implantation devices utilize movable claspers for both positioning and anchoring the valve prostheses within the native cardiac valve, minimizing the extent of imaging necessary.09-30-2010
20100249916METHODS AND DEVICES FOR TRANSAPICAL DELIVERY OF A SUTURELESS VALVE PROSTHESIS - A method for delivering a sutureless cardiac valve prosthesis using a transapical approach is provided. The implantation device utilizes movable claspers for both positioning and anchoring the valve prosthesis within the native cardiac valve, minimizing the extent of imaging necessary.09-30-2010
20100249915VALVE PROSTHESIS WITH MOVABLY ATTACHED CLASPERS WITH APEX - A valve prosthesis, implantation device, and methods for use are provided. The implantation device utilizes movable claspers for both positioning and anchoring the valve prosthesis. Alternative designs of the devices allow different methods for minimally invasive implantation of a sutureless valve prosthesis, including transapical and transcatheter approaches. Also provided is a delivery device for delivery of a medical prosthesis though minimally invasive means.09-30-2010
20120165926Methods and Devices for Delivery of Prosthetic Heart Valves and Other Prosthetics - Prosthetic valves and their component parts are described, as are prosthetic valve delivery devices and methods for their use. The prosthetic valves are particularly adapted for use in percutaneous aortic valve replacement procedures. The delivery devices are particularly adapted for use in minimally invasive surgical procedures. The preferred delivery device includes a catheter having a deployment mechanism attached to its distal end, and a handle mechanism attached to its proximal end. A plurality of tethers are provided to selectively restrain the valve during deployment. A number of mechanisms for active deployment of partially expanded prosthetic valves are also described.06-28-2012
20120165925FIXING DEVICE, IN PARTICULAR FOR FIXING TO VASCULAR WALL TISSUE - An arrangement includes a first sleeve; a fixing device for fixing to vascular wall tissue; and a second sleeve. The fixing device includes a tubular element for accommodation within a passage surrounded by vascular wall tissue and is provided with fingers arranged distributed in the peripheral direction of the tubular element. The fingers have a first position in which they project radially outwards from the tubular element. The fingers are bent aside reversibly, against a resilient force, from the first position into a second position in which the projection of the fingers on a radial transverse surface of the tubular element is located essentially on and/or within the periphery of the tubular element. The fingers are fixed in the second position by the first sleeve in which the tubular element and fingers, which are in the second position, are accommodated to form a composite assembly.06-28-2012
20120165924Method and Device for Treatment of Mitral Insufficiency - A device for treatment of mitral annulus dilation is disclosed, wherein the device comprises two states. In a first of these states the device is insertable into the coronary sinus and has a shape of the coronary sinus. When positioned in the coronary sinus, the device is transferable to the second state assuming a reduced radius of curvature, whereby the radius of curvature of the coronary sinus and the radius of curvature as well as the circumference of the mitral annulus is reduced.06-28-2012
20120083877EXPANDABLE SHEATH FOR INTRODUCING AN ENDOVASCULAR DELIVERY DEVICE INTO A BODY - Embodiments of an expandable sheath can be used in conjunction with a catheter assembly to introduce a prosthetic device, such as a heart valve, into a patient. Such embodiments can minimize trauma to the vessel by allowing for temporary expansion of a portion of the introducer sheath to accommodate the delivery apparatus, followed by a return to the original diameter once the prosthetic device passes through. Some embodiments can include a sheath with inner and outer layers, where a folded portion of the inner layer extends through a slit in the outer layer and a portion of the outer layer overlaps the folded portion of the inner layer. Some embodiments include an elastic outer cover positioned outside the outer layer. Embodiments of the present expandable sheath can avoid the need for multiple insertions for the dilation of the vessel, thus offering advantages over prior art introducer sheaths.04-05-2012
20120083876PREPARATION METHODS FOR TRANSCATHETER HEART VALVE DELIVERY SYSTEMS - A delivery device for a collapsible prosthetic heart valve includes a support shaft around which a compartment is defined, an inner shaft extending through the support shaft and adapted to slide relative to the support shaft along a longitudinal axis thereof, the inner shaft having a lumen therethrough, and a distal sheath operatively connected at a distal end to the inner shaft and slidable therewith. The compartment may receive the valve in an assembled condition, and may be selectively covered and uncovered by the distal sheath. A first flow path may provide flow communication between the lumen of the inner shaft and the compartment.04-05-2012
20120083875ASSEMBLY AND METHOD FOR LOADING A SELF-EXPANDING COLLAPSIBLE HEART VALVE - An assembly for collapsing a prosthetic heart valve includes a compression member and a pusher member. The compression member has a first open end with a first diameter, a second open end with a second diameter less than the first diameter, and a tapered wall between the first open end and the second open end. The pusher member has a base adapted to engage an end of the valve. The pusher member and the compression member are movable relative to one another between an initial position in which the base of the pusher member is relatively far from the first open end of the compression member and an operative position in which the base of the pusher member is relatively close to the first open end of the compression member. Movement of the pusher and compression members from the initial position to the operative position radially compresses the valve.04-05-2012
20120215302Annuloplasty Ring Holder - An annuloplasty ring holder including a head having an upper surface and an annuloplasty ring receiving surface facing opposite the upper surface. The annuloplasty ring holder also includes means for attaching an annuloplasty ring to the annuloplasty ring receiving surface. The means for attaching an annuloplasty ring to the annuloplasty ring receiving surface may include one or more suture guides operatively associated with the head and configured to position one or more sutures to removably associate an annuloplasty ring with the annuloplasty ring receiving surface. The head may include a central hub and more than one spoke radiating out from the central hub. If the head is thus configured, each spoke will include a portion of the annuloplasty ring receiving surface.08-23-2012
20120136433INTRAOPERATIVE AND POST-OPERATIVE ADJUSTMENT OF AN ANNULOPLASTY RING - An intraoperative adjustment device is described. In some embodiments, the device includes an elongate body including a proximal end and a distal end, the distal end configured to penetrate an outer surface of an adjustable cardiac implant implanted in a patient's heart, and the proximal end and the distal end connected by at least one energy-transfer member. In some embodiments, the distal end includes at least one electrode coupled to the energy-transfer member and configured to deliver an activation energy to the adjustable cardiac implant. In some embodiments, the proximal end is configured to attach to an energy source that provides the activation energy. In some embodiments, the proximal end is configured to be located outside the patient's body while the distal end is coupled to the adjustable cardiac implant that is implanted in the patient's heart.05-31-2012
20100174363One Piece Prosthetic Valve Support Structure and Related Assemblies - Valve prostheses are disclosed that are adapted for secure and aligned placement relative to a heart annulus. The valve prostheses may be placed in a non-invasive manner, e.g., via trans-catheter techniques. The valve prosthesis may include a support ring, a plurality of leaflet membranes mounted with respect to the support ring, and a plurality of retention clip elements. The support structure is advantageously formed from a tubular member or flat stock of shape memory metal. A delivery system for delivery of a valve prosthesis embodying the disclosed support structure is also disclosed.07-08-2010
20100174362Medical Device for Treating A Heart Valve Insufficiency or Stenosis - A medical device for treating a heart valve insufficiency, with an endoprosthesis which can be introduced into a patient's body and expanded to secure a heart valve prosthesis in the patient's aorta with a catheter. In an embodiment, the endoprosthesis has a plurality of positioning arches configured to be positioned with respect to a patient's aorta and a plurality of retaining arches to support a heart valve prosthesis. The endoprosthesis includes a collapsed mode during the process of introducing it into the patient's body and an expanded mode when it is implanted. The endoprosthesis may be introduced into a patient's body and expanded via a catheter. In an embodiment, the catheter has first and second slide mechanisms configured to independently manipulate first and second sleeve elements to sequentially expand the endoprosthesis from the collapsed mode to the expanded mode.07-08-2010
20120316641Device and Method for Reducing Cardiac Valve Regurgitation - A catheter (12-13-2012
20120316640Device And Method For Improving Function Of Heart Valve - A device for improving the function of a heart valve comprises a first loop-shaped support, which is configured to abut a first side of the heart valve, and a first flange unit being connected to said first loop-shaped support. The flange unit is configured to be arranged against said annulus when said first loop-shaped support is abutting said heart valve.12-13-2012
20100049313PROSTHETIC HEART VALVE AND DELIVERY APPARATUS - Embodiments of the present disclosure provide a prosthetic heart valve and a heart valve delivery apparatus for delivery of the prosthetic heart valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic valve through the aorta (i. e., in a retrograde approach) for replacing a diseased native aortic valve. In one embodiment, a self-expanding valve comprises an expandable stent that is shaped to maintain the valve in the aortic annulus against axial without anchors or retaining devices that engage the surrounding tissue. A delivery apparatus for delivering s self-expanding prosthetic valve can be configured to allow controlled and precise deployment of the valve from a valve sheath so as to minimize or prevent jumping of the valve from the valve sheath.02-25-2010
20100049312AORTIC VALVE REPLACEMENT - A device for replacement of a bioprosthetic valve having an annulus (02-25-2010
20100298930ACCESS TO THE LEFT ATRIUM AND REDUCTION OF MITRAL VALVE LEAFLET MOBILITY - Disclosed are a method for engaging cardiac valve leaflets, including a) directing a distal end of an elongated catheter body of a leaflet-engaging device into a coronary sinus of a heart, b) passing a first leaflet-engaging component located proximate to the distal end of the elongated catheter body of the leaflet-engaging device through cardiac tissue separating the coronary sinus and a left atrium of the heart to enter a left atrium of the heart, and c) engaging a first cardiac valve leaflet with the first leaflet-engaging component, thereby engaging at least one cardiac valve leaflet. Related apparatus and methods are also described.11-25-2010
20100298931VASCULAR IMPLANT AND DELIVERY SYSTEM - A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant is verified prior to full release. The implant can be at least partially resheathed and repositioned if desired.11-25-2010
20080208329HANDLE MECHANISM TO ADJUST A MEDICAL DEVICE - An apparatus for adjusting the position and orientation of a medical device within a patient's body includes a distal portion, a body portion and a proximal portion. The distal portion has a lumen for receiving at least three control tubes. Each control tube houses a control wire that is attached to the medical device. The body portion is connected to the distal portion by a ball-and-socket joint and configured to receive at least one control wire. The proximal portion is rotatably and slidably attached to the body portion and configured to receive at least one control wire.08-28-2008
20120179244Device and System for Transcatheter Mitral Valve Replacement - This invention relates to the design and function of a compressible valve replacement prosthesis which can be deployed into a beating heart without extracorporeal circulation using a transcatheter delivery system. The design as discussed focuses on the deployment of a device via a minimally invasive fashion and by way of example considers a minimally invasive surgical procedure preferably utilizing the intercostal or subxyphoid space for valve introduction. In order to accomplish this, the valve is formed in such a manner that it can be compressed to fit within a delivery system and secondarily ejected from the delivery system into the annulus of a target valve such as a mitral valve or tricuspid valve.07-12-2012
20120179245METHODS OF ASSEMBLING AND DELIVERING AN ANNULOPLASTY RING - A holder for an annuloplasty ring having a template defining a proximal face opposite the distal face, and a peripheral edge about which the annuloplasty ring conforms. The annuloplasty ring anchors to the template using one or more flexible filaments. The template includes a single cutting well on its proximal face over which the flexible filament is suspended. Desirably, the single cutting well is located adjacent the peripheral edge so as to be away from any handle connections for ease of access. The flexible filament emerges above the proximal face of the template at only one location at the cutting well, thus presenting a one cut quick-release structure that is highly visible to the surgeon.07-12-2012
20120179243METHODS AND APPARATUSES FOR DEPLOYING MINIMALLY-INVASIVE HEART VALVES - A method for replacing native valve function of a diseased aortic valve in a patient is provided. The method comprises: (a) guiding a catheter system having a balloon through the vasculature of the patient; (b) guiding an artificial heart valve assembly through the vasculature of the patient; (c) while the catheter system is in the patient's vasculature, positioning the artificial heart valve assembly about the balloon of the catheter system; (d) delivering the artificial heart valve assembly to the region of the diseased aortic valve; (e) while the patient's heart is beating, expanding the artificial heart valve assembly in the region of the diseased aortic valve; and (f) withdrawing the catheter system from the patient's vasculature.07-12-2012
20090030510METHODS AND APPARATUS FOR PERCUTANEOUS AORTIC VALVE REPLACEMENT - A delivery system and method for percutaneous aortic valve (PAV) replacement and apparatus used therein. A temporary aortic valve comprised of a reversibly expandable occluding means, such as balloons, surrounds a central catheter mechanism. The temporary valve is positioned within the ascending aorta, just above and downstream from the coronary ostia. The occluding means is configured such that, when fully expanded against the aortic wall, gaps are left that promote continuous coronary perfusion during the cardiac cycle. The temporary valve with occluding means substitutes for the function of the native aortic valve during its replacement. The native aortic valve is next dilated, and then ablated through deployment of low profile, elongated, sequentially delivered stents. The ablation stent(s) displace the native valve tissues and remain within the aortic annulus to receive and provide a structure for retaining the PAV. The PAV is delivered, positioned and deployed within the ablation stent(s) at the aortic annulus with precision and relative ease. Ablation of the native aortic valve removes the structural obstacles to precise PAV placement. The temporary aortic valve mediates the hemodynamic forces upon the devices as encountered by the surgeon following native valve ablation. The temporary valve also promotes patient stability through continuous coronary perfusion and a moderated transvalvular pressure gradient and regurgitation. Sequential delivery of low profile PAV components minimize the risk of trauma and injury to vascular tissues. Mathematical considerations for determining the optimum cross-sectional area for the temporary valve blood perfusion gaps are also described.01-29-2009
20120232645DEVICES, SYSTEMS, AND METHODS FOR RESHAPING A HEART VALVE ANNULUS, INCLUDING THE USE OF MAGNETIC TOOLS - Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools.09-13-2012
20110004298ANNULOPLASTY APPARATUS AND METHODS - An annuloplasty system for repairing a valve in a patient's heart comprises a surgical implant including a member having first and second end portions. The implant member further is configured and/or adapted to form a partial ring along a portion of one of the valve annulae of a patient's heart such as the mitral or tricuspid valve annulus. The implant member is axially elastic such that it can axially expand and contract and includes first and second anchors extending from the end portions of the implant member. The anchors are adapted to anchor the implant in tissue such as the mitral or tricuspid valve annulus. The system can facilitate tissue plication (e.g., of the posterior annulus of the mitral valve or the annulus of the tricuspid valve) and reinforcement of a valve annulus.01-06-2011
20120239142PROSTHETIC HEART VALVE DELIVERY APPARATUS - Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.09-20-2012
20110046725METHOD OF IMAGING FOR HEART VALVE IMPLANT PROCEDURE - A method as a workflow for imaging for a heart valve implant procedure includes positioning the patient and an articulated imaging apparatus relative to one another, inducing rapid ventricular pacing in the patient, and imaging a region of the patient's heart to obtain image date for a three-dimensional image. The three-dimensional data is used to construct a three-dimensional image of the region of the patient's heart an the three-dimensional image is displayed for use in the implanting of the replacement heart valve. Optional steps may include obtaining a real time two-dimensional image of the patient's heart and superimposing the real time two-dimensional image with the constructed three dimensional image. The replacement valve is moved into position in the patient's heart during rapid ventricular pacing and breath hold using the superimposed two-dimensional and three-dimensional image information.02-24-2011
20120323314EPICARDIAL CLIP - An epicardial clip for reshaping the annulus of the mitral valve of a heart includes a curved member having an anterior segment configured to be positioned in the transverse sinus of the heart, a posterior segment configured to be positioned on the posterior side of the heart, such as on or inferior to the atrioventricular groove, and a lateral segment extending between the anterior segment and the posterior segment. The lateral segment includes a curve such that the first end of the member is positioned at or above the plane of the mitral valve and the second end of the member is positioned at or below the plane of the mitral valve.12-20-2012
20120330408SYSTEM FOR LOADING A COLLAPSIBLE HEART VALVE - An assembly for collapsing a self-expanding prosthetic heart valve includes a compression member, a support member and a constricting member. The compression member has a tapered wall between its first open end and its second open end, the tapered wall defining an open space adapted to receive the valve. The support member has a base and a recess adapted to receive an end of the valve. The support member and the compression member are movable toward one another to compress the valve and push it through a relatively small aperture in the second open end of the compression member. The second end of the constricting member is sized to receive the compressed valve from the second open end of the compression member for loading into a delivery device.12-27-2012
20120330407APPARATUS AND METHOD FOR HEART VALVE REPAIR - A transcatheter method of gathering tissue of a heart valve leaflet may include inserting an elongated catheter assembly to a position adjacent the heart valve leaflet, the catheter assembly including a capture tool moveable between a retracted position and an extended position, a tissue support, and a clamping member moveable between an open position and a closed position. The capture tool may be partially retracted to gather tissue of the heart valve leaflet between the tissue support and the clamping member. The clamping member may then be moved from the open position toward the closed position so as to clamp a substantial portion of the gathered tissue of the heart valve leaflet between the tissue support and the clamping member. Subsequently, a clip may be applied from the catheter assembly to the clamped tissue so as to hold the clamped tissue substantially in a gathered configuration.12-27-2012
20120323313PROSTHETIC LEAFLET ASSEMBLY FOR REPAIRING A DEFECTIVE CARDIAC VALVE AND METHODS OF USING THE SAME - Methods and apparatus are provided for repairing or replacing a defective cardiac valve including a prosthetic leaflet assembly having an expandable frame with one or more anchors configured to engage a predetermined region of the defective cardiac valve in an expanded deployed state, and at least one prosthetic leaflet coupled to the expandable frame. The prosthetic leaflet assembly is configured such that the prosthetic leaflet is suspended within a flow path of the defective cardiac valve and coapts with, and improves functioning of, one or more native leaflets of the defective cardiac valve.12-20-2012
20110238165SURGICAL DEVICE FOR CONNECTING SOFT TISSUE - The invention comprises a surgical instrument including an external tube (09-29-2011
20110238164Device and Method for Placing and Positioning a Heart Valve - A positioning tool comprises an elongate positioning member having a first end and a second end, a tubular positioning body coupled to the first end of the elongate positioning member and including a first end, a second end, and an attachment structure disposed within an open center of the positioning body, and a plurality of pairs of alignment apertures, each pair of alignment apertures including a first alignment aperture adjacent to the first end of the positioning body and a second alignment aperture adjacent to the second end of the positioning body.09-29-2011
20120277853System and Method for Percutaneous Mitral Valve Repair - A system for minimally invasive repair of a mitral valve including a catheter, a capture body and a surgical fastener. The capture body includes legs extending from a center portion, and is self-transitionable from a collapsed arrangement to a normal arrangement in which the legs extend in a common wind direction. The fastener has a self-closing clip forming a loop in an undeflected arrangement. In a delivery state, the capture body and fastener are disposed within the catheter and forced to the collapsed and deflected arrangements, respectively. In a capture state, the capture body legs are distal the catheter and self-assume the normal arrangement for capturing chordae. In a release state, the fastener is released from the catheter and the clip self-transitions toward the undeflected arrangement for securing the mitral valve leaflets.11-01-2012
20120277854Delivery Systems and Methods of Implantation for Replacement Prosthetic Heart Valves - A method of delivering a replacement prosthetic valve to a previously implanted prosthetic valve including the steps of compressing a replacement prosthetic valve having an expandable stent within a sheath of a delivery system, wherein the delivery system comprises a proximal end, a distal end, and a centering structure positioned between the proximal and distal ends, advancing the delivery system and compressed replacement prosthetic valve into a vessel of a patient until the distal end of the delivery system is positioned adjacent to a second side of a previously implanted prosthetic valve, deploying the centering structure to radially reposition the distal end of the delivery system, further advancing the delivery system toward the previously implanted prosthetic valve, and deploying the replacement prosthetic valve11-01-2012
20110257733Transcatheter Prosthetic Heart Valve Delivery System and Method with Expandable Stability Tube - A device for percutaneously delivering a stented prosthetic heart valve. The device includes an inner shaft assembly, a delivery sheath assembly, an outer stability tube, and a handle. The sheath assembly is slidably disposed over the inner shaft, and includes a capsule and a shaft. The capsule compressively contains the prosthesis over the inner shaft. The stability tube is slidably disposed over the delivery sheath, and includes a distal region configured to be radially expandable from a first shape having a first diameter to a second shape having a larger, second diameter. In a first delivery state, the distal region assumes the first shape, providing a low profile appropriate for traversing a patient's vasculature. In a second delivery state, the distal region has the expanded diameter second shape, sized to receive the capsule, such as when retracting the capsule to implant the prosthesis.10-20-2011
20110251679Transcatheter Prosthetic Heart Valve Delivery System and Method With Stretchable Stability Tube - A device for percutaneously delivering a stented prosthetic heart valve. The device includes an inner shaft, a delivery sheath, stability tube, and a handle. The delivery sheath is slidably disposed over the inner shaft, and includes a capsule compressively containing the prosthesis over the inner shaft. The stability tube is coaxially received over the delivery sheath, and includes a distal region. A circumferential rigidity of the capsule is greater than a circumferential rigidity of the distal region. In transitioning from a delivery state to a deployed state, the capsule is withdrawn from the prosthetic heart valve and at least partially into the distal region to permit the prosthesis to self-deploy. The capsule forces the distal region to stretch and expand in diameter.10-13-2011
20110276128Prosthetic Heart Valve - Disclosed prosthetic valves can comprise a sewing ring configured to secure the valve to an implantation site. Some disclosed valves comprise a resiliently collapsible frame having a neutral configuration and a collapsed deployment configuration. Some disclosed frames can self-expand to the neutral configuration when released from the collapsed deployment configuration. Collapsing a disclosed valve can provide convenient access to the sewing ring, such as for securing the valve to the implantation site, as well as for the insertion of the valve through relatively small surgical incisions.11-10-2011
20110276127MULTIPLE INFLATION OF AN EXPANDABLE MEMBER AS A PRECURSOR TO AN IMPLANT PROCEDURE - Devices and methods for assessing the orientation and shape of vessel lumens and hollow portions of organs are described. The devices and methods are particularly adapted for determining the orientation and shape of the native heart valves to facilitate the later implantation of a prosthetic heart valve. The devices are typically catheter-based having an expandable member fixed to a distal end of the catheter. The devices and methods typically comprise deploying the expandable member percutaneously to a target location, expanding the expandable member, performing a valvuloplasty procedure to enlarge the diseased lumen and then performing an assessment of the diseased lumen with the expandable member to determine at least one property of the lumen. An implant device is inserted after assessment of the diseased lumen.11-10-2011
20120095549Prosethetic Haert Valves, Scaffolding Structures, and Systems and Methods for Implantation of Same - Prosthetic valves and their component parts are described, as are prosthetic valve delivery devices and methods for their use. The prosthetic valves are particularly adapted for use in percutaneous aortic valve replacement procedures. The delivery devices are particularly adapted for use in minimally invasive surgical procedures.04-19-2012
20110319990DEVICES, SYSTEMS, AND METHODS FOR SUPPLEMENTING, REPAIRING OR REPLACING A NATIVE HEART VALVE LEAFLET - An implant for supplementing, repairing, or replacing a native heart valve leaflet or leaflets provides a scaffold, which defines a pseudo-annulus. The implant further has at least two struts in generally oppositely spaced apart positions on the scaffold. The scaffold can be placed in an elastically loaded condition in a heart with the struts engaging tissue at or near the leaflet commissures of a heart valve annulus, to reshape the annulus for leaflet coaptation. The implant further provides a neoleaflet element coupled to the scaffold within pseudo-annulus, to provide a one-way valve function.12-29-2011
20110319989TRANSCATHETER MITRAL VALVE PROSTHESIS - A prosthetic cardiac valve comprises an anchor having an atrial skirt, an annular region, and a ventricular skirt. The prosthetic valve also has a plurality of prosthetic valve leaflets each having a first end and a free end. The first end is coupled with the anchor and the free end is opposite the first end. The prosthetic cardiac valve has an open configuration in which the free ends of the prosthetic valve leaflets are disposed away from one another to allow antegrade blood flow therepast, and a closed configuration in which the free ends of the prosthetic valve leaflets engage one another and substantially prevent retrograde blood flow therepast. The anchor has a collapsed configuration for delivery to the heart and an expanded configuration for anchoring the prosthetic cardiac valve to a patient's heart.12-29-2011
20110319988Device and System for Transcatheter Mitral Valve Replacement - This invention relates to the design and function of a compressible valve replacement prosthesis which can be deployed into a beating heart without extracorporeal circulation using a transcatheter delivery system. The design as discussed focuses on the deployment of a device via a minimally invasive fashion and by way of example considers a minimally invasive surgical procedure preferably utilizing the intercostal or subxyphoid space for valve introduction. In order to accomplish this, the valve is formed in such a manner that it can be compressed to fit within a delivery system and secondarily ejected from the delivery system into the annulus of a target valve such as a mitral valve or tricuspid valve.12-29-2011
20100185275MODULAR PERCUTANEOUS VALVE STRUCTURE AND DELIVERY METHOD - A modular prosthetic valve device for implantation in a patient is disclosed. The valve device is designed as two or more modules to be delivered unassembled and combined into an assembled valve device in the body—e.g., in the body at or near the site where implantation occurs. The two or more modules may be a support structure and a valve assembly. The valve assembly may be formed from two or more valve sections. Because the valve device of the invention is deliverable as modules, it may have a smaller delivery diameter than pre-assembled percutaneous valves and permits use of a delivery device of reduced diameter. Delivering the valve device as modules increases the flexibility of the valve device during delivery, compared to percutaneous valve devices in the art. The invention further provides a system for and method of delivering such a modular valve device and assembling it in vivo. The modules of the valve device may be connected by pull wires for delivery sequentially to or near the implantation site in the body lumen, and then assembled by remote manipulation using the pull wires. The system may further include a temporary valve that may be deployed to maintain valvular function while the device modules are assembled. The temporary valve may be attached to the delivery device and deployed either before or after the support structure is expanded, or the temporary valve may be attached to the support structure and deployed when the support structure is expanded. Various locking mechanisms are provided for attaching the device modules together.07-22-2010
20120136434ERGONOMIC MITRAL HEART VALVE HOLDERS - A holder for a prosthetic mitral heart valve that attaches to an inflow end of the valve and includes a simple tensioning mechanism that flexes the heart valve commissure posts inward to help prevent suture looping. The tensioning mechanism may include relatively movable rings of the holder or a generally unitary holder with a tensor, or rotatable knob. Connecting sutures thread through internal passages in the holder and travel in the outflow direction along valve commissure posts, emerging at the post tips and mutually crossing over the outflow side of the valve. A handle attaches off-center on the holder to increase visualization of and access to the heart valve through a central window. The holder is constructed of non-metallic materials so as to avoid interfering with imaging devices, and the handle is ergonomically curved and shaped to facilitate manipulation. The holder may be shaped as a ring with an open inner diameter for enhanced access to the commissure posts and leaflets.05-31-2012
20100198346Method for Guiding a Medical Device - A device and method for valve replacement or valve repair is disclosed comprising the steps of acquiring an anatomical image of a patient, correlating the image to the patient, guiding a valve replacement delivery member or a valve repair delivery member within the patient while tracking the position of the delivery member in the patient, positioning the valve replacement member or valve repair member in a desired position to place a valve or repair valve and removing the delivery member from the patient. In one aspect of the invention, a delivery system is provided for percutaneous delivery of a heart valve to a predetermined position in the heart of a patient, where the delivery system itself includes features that allow it to be accurately positioned in the heart. In another aspect of the invention, a delivery system is provided for percutaneous repair of a heart valve in the heart of a patient, where the repair system itself includes features that allow it to be accurately positioned in the heart. In another aspect of the invention, a method and device are provided that involve imaging a native root using an interoperative technique, then introducing a device that is easily visualized in a chosen imaging modality.08-05-2010
20130013057MEDICAL IMPLANT DEPLOYMENT TOOL - A medical implant deployment tool and deployment method are disclosed. One aspect of the invention provides an implant system including an implant adapted for endovascular delivery and deployment; and a deployment tool adapted to deploy the implant, with the deployment tool having an actuation controller; a plurality of actuation elements adapted to apply forces to one or more implant deployment mechanisms and each adapted to extend along an actuation element path within a patient's vasculature; and an actuation element compensation mechanism adapted to compensate for differences in length between the actuation element paths.01-10-2013
20130013056Valve Repair Instrument - A valve repair instrument and method of repair for the mitral valve of the heart is disclosed. The valve repair instrument includes an elongated body having two ends. One of the ends being configured to maintain a muscle portion of a valve repair device in an expanded position for attachment to the papillary muscle, the other end being configured to maintain a leaflet portion of a valve repair device in an expanded position for attachment to a valve leaflet. The valve repair device is attached to the diseased valve by suturing the leaflet portion to the affected leaflet and suturing the muscle portion to the affected muscle.01-10-2013
20120150289Methods and Devices for Delivery of Prosthetic Heart Valves and Other Prosthesis - Prosthetic valves and their component parts are described, as are prosthetic valve delivery devices and methods for their use. The prosthetic valves are particularly adapted for use in percutaneous aortic valve replacement procedures. The delivery devices are particularly adapted for use in minimally invasive surgical procedures. The preferred delivery device includes a catheter having a deployment mechanism attached to its distal end, and a handle mechanism attached to its proximal end. A plurality of tethers are provided to selectively restrain the valve during deployment. A number of mechanisms for active deployment of partially expanded prosthetic valves are also described.06-14-2012
20110160848METHODS FOR CROSSING A HEART VALVE - The present invention provides for methods of using guide wires adapted for passage across a heart valve. The guide wires have an increased diameter and a shorter, relatively floppy distal tip; the increased diameter providing improved pushability to facilitate positioning in a blood jet and passage through a heart valve. The distal tip comprises a section of rectangular cross-section that, in conjunction with the decreased tip length, causes the distal tip to vibrate, or “dance”, when positioned within a blood jet at the outlet of a heart valve. This vibratory motion may be used to position the distal tip within the blood jet, thus facilitating passage through the valve without damage to leaflets of the valve or emboli generation.06-30-2011
20110160847APPARATUS FOR DELIVERY AND DEPLOYMENT OF AN EXPANDABLE STENT WITHIN A BLOOD VESSEL - An improved apparatus for delivering and deployment of an expandable stent with a protection sheath within a blood vessel is provided. The system comprises a fluid pressure device which is coupled with a retraction device for the protection sheath such that after retraction of the protection sheath the stent is automatically deployed by the fluid pressure device. The advantage of the invention is an easy and simple operation of the apparatus.06-30-2011
20110160846TRANSLUMENALLY IMPLANTABLE HEART VALVE WITH FORMED IN PLACE SUPPORT - A cardiovascular prosthetic valve, the valve comprising an inflatable cuff comprising at least one inflatable channel that forms, at least in part, an inflatable structure, and a valve coupled to the inflatable cuff, the valve configured to permit flow in a first axial direction and to inhibit flow in a second axial direction opposite to the first axial direction, the valve comprising a plurality of tissue supports that extend generally in the axial direction and that are flexible and/or movable throughout a range in a radial direction.06-30-2011
20130172990METHOD AND SYSTEM FOR PLICATING TISSUE IN A MINIMALLY INVASIVE MEDICAL PROCEDURE FOR THE TREATMENT OF MITRAL VALVE REGURGITATION - A system and method for the treatment of mitral valve regurgitation by reshaping the mitral valve annulus using one or more plications of annular or adjacent tissue each fixed by a retainer is described. The system includes four devices to achieve such percutaneous direct plication annuloplasty. The first is a crossing catheter having a prolapseable or curved tip. Second, a deflecting guide catheter is used to provide a means for guiding the plication device into proper position at the subvalvular region of the mitral valve annulus. Third, the plication device is then used to make plications in the subvalvular region of the mitral valve annulus. Fourth, a “C” shaped retainer with deformable ends is deployed by the plication device in order to retain the plicated tissue in the plicated form.07-04-2013
20130172991PROSTHETIC VASCULAR CONDUIT AND ASSEMBLY METHOD - A kit for implanting a prosthetic vascular conduit includes a prosthetic vascular conduit for coupling to a prosthetic valve having an annular portion. The conduit includes a terminal collar member for receiving the valve. The kit further includes a holder including a shaft and a hub including a receiving portion configured for housing a prosthetic valve. The conduit is fitted on the holder so that at least a portion of the conduit wraps over the receiving portion of the hub. A sleeve member fitted onto the conduit in a position corresponding to the receiving portion of the hub, and a portion of the collar member is wrapped or folded over the sleeve member. The sleeve member is slidable away from the hub to unwrap the collar member such that it is disposed around the annular portion of a prosthetic valve.07-04-2013
20130172992TECHNIQUES FOR PERCUTANEOUS MITRAL VALVE REPLACEMENT AND SEALING - Apparatus and methods are described including a prosthetic valve support (07-04-2013
20080249620VALVE HOLDER - A valve holder assembly having a main valve holder and a detachable secondary valve holder for positioning a heart valve prosthesis and a method of implanting a stentless heart valve prosthesis are disclosed.10-09-2008
20080249618Repair of Incompetent Heart Valves by Interstitial Implantation of Space Occupying Materials or Devices - Incompetency or regurgitation of a cardiac valve is treated by injecting a space occupying material(s) or implanting a space occupying device(s) at an interstitial location adjacent to the valve such that the space occupying material or device exerts pressure on the valve causing one or more leaflets of the valve to be favorably repositioned. The procedure may be performed by open thoracotomy, thorascopically or transluminally using a tissue penetrating catheter.10-09-2008
20080243245Percutaneous Heart Valve Prosthesis - A percutaneous heart valve prosthesis (10-02-2008
20080234814Low Profile Heart Valve and Delivery System - Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: inserting a catheter having a diameter no more than 21 french into the patient; endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve through the catheter; and deploying the anchor and the replacement valve.09-25-2008
20110264201Transcatheter Prosthetic Heart Valve Post-Dilatation Remodeling Devices and Methods - A system and method for restoring (e.g., replacing) a defective heart valve of a patient. A delivery system is manipulated to percutaneously deliver and implant a stented prosthetic heart valve to a native heart valve. A post-dilatation balloon is percutaneously delivered to the implantation site, and a compliant segment thereof is arranged within a region of the implanted prosthesis. The balloon is inflated such that the compliant segment expands and contacts the prosthesis, expanding a remodeling region of the prosthesis to a remodeled state. With these and related techniques, remodeling of an implanted, stented prosthetic heart valve to better match the native valve shape is possible, providing many benefits such as reducing the risk of paravalvular leaks.10-27-2011
20130144380VASCULAR IMPLANT AND DELIVERY SYSTEM - A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant can be verified prior to full release. The implant can be at least partially resheathed and repositioned if desired.06-06-2013
20130144381REPLACEMENT HEART VALVES, DELIVERY DEVICES AND METHODS - A replacement heart valve and method of treating valve insufficiency includes an expandable frame configured to engage a native valve annulus. A valve body is coupled to the frame. The valve body can include a leaflet portion and possibly a skirt portion. A portion of the frame has a foreshortening portion configured to longitudinally expand when urged to a radially compacted state and longitudinally contract when urged to a radially expanded state. In one embodiment the valve skirt is attached to the frame so that it can adapt to changes in the length of the frame. A delivery device in some embodiments can use one or more coverings, such as sheaths, to controllably release the replacement heart valve at a native heart valve.06-06-2013
20130090727Methods and Devices for Delivery of Prosthetic Heart Valves and Other Prosthetics - Prosthetic valves and their component parts are described, as are prosthetic valve delivery devices and methods for their use. The prosthetic valves are particularly adapted for use in percutaneous aortic valve replacement procedures. The delivery devices are particularly adapted for use in minimally invasive surgical procedures. The preferred delivery device includes a catheter having a deployment mechanism attached to its distal end, and a handle mechanism attached to its proximal end. A plurality of tethers are provided to selectively restrain the valve during deployment. A number of mechanisms for active deployment of partially expanded prosthetic valves are also described.04-11-2013
20130090725UNITARY QUICK-CONNECT PROSTHETIC HEART VALVE DEPLOYMENT METHODS - A quick-connect heart valve prosthesis that can be quickly and easily implanted is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable coupling stent, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the coupling stent attached thereto. The coupling stent may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes a hollow two-piece handle through which a balloon catheter passes. A valve holder is stored with the heart valve and the handle easily attaches thereto to improve valve preparation steps.04-11-2013
20130090724TRANSVALVULAR INTRAANULAR BAND AND CHORDAE CUTTING FOR ISCHEMIC AND DILATED CARDIOMYOPATHY - Mitral valve prolapse and mitral regurgitation can be treating by implanting in the mitral annulus a transvalvular intraannular band. The band is positioned so that it extends transversely across a coaptive edge formed by the closure of the mitral valve leaflets, to inhibit prolapse into the left atrium. At least one marginal chordae is severed, to permit leaflet closure against the band.04-11-2013
20130096671METHOD OF IMPLANTING A SELF-EXPANDABLE PROSTHETIC HEART VALVE - A method of implanting a collapsible prosthetic heart valve is disclosed. The prosthetic heart valve includes three biological leaflets mounted within a self-expanding tubular leaflet frame formed of nitinol. The method comprises loading a collapsed prosthetic heart valve into a distal end of a delivery tube. The distal end of the delivery tube is inserted into a vasculature of a patient and positioned proximal to an aortic valve. The prosthetic heart valve is expelled into an annulus of the aortic valve and allowed to self-expand to a first diameter. A balloon is then inflated within the prosthetic heart valve for expanding the prosthetic heart valve to a second diameter, wherein the second diameter is larger than the first diameter, thereby securely implanting the prosthetic heart valve within the annulus of the aortic valve.04-18-2013
20130096672APPARATUS AND METHOD FOR GUIDE-WIRE BASED ADVANCEMENT OF A ROTATION ASSEMBLY - Apparatus is provided, comprising (1) a guide member, (2) a tissue-adjustment mechanism having (a) an upper surface and a lower surface, (b) at least one first opening at the upper surface, (c) at least one second opening at the lower surface, and (4) a channel extending between the first and second openings, the channel facilitating advancement of the tissue-adjustment mechanism along the guide member; and (3) at least one repair chord coupled at a first portion thereof to the tissue-adjustment mechanism and having at least a first end that is configured to be coupled to a portion of tissue of a patient, the repair chord being configured to adjust a distance between the portion of tissue and the tissue-adjustment mechanism, in response to adjustment of the repair chord by the tissue-adjustment mechanism. Other embodiments are also described.04-18-2013
20130123911TRANSAPICAL COLLAPSIBLE VALVE REFERENCE FIXTURE - A device for positioning a reference element during aortic valve implantation surgery. The device includes a first extension member having a proximal end and a distal end, a connection member adapted to connect the first extension member to a support, and a coupling having a first end connected to the connection member and a second end connected to the proximal end of the first extension member so that the first extension member is moveable in multiple planes relative to the support. At least one reference datum is operatively connected to the distal end of the first extension member and extends in a straight line, the reference datum being moveable between a first position and a second position to enable precise locating of the reference datum during the aortic valve implantation surgery.05-16-2013
20110313516PERCUTANEOUS MAGNETIC CATHETER - A percutaneous magnetic catheter may be used to position one or more magnetic components near a magnetically driven prosthesis in a patient's heart in order to adjust the magnetically driven prosthesis. In certain embodiments, the one or more magnetic components are rotatable. Rotation of the one or more magnetic components cause variations in a magnetic field. Variations in the magnetic field may be utilized to adjust the size or shape of a magnetically driven prosthesis. In this way, a magnetically driven prosthesis may be adjusted after a patient has recovered from a surgery in which the magnetically driven prosthesis was implanted. Further, a magnetically driven prosthesis may be adjusted based upon progression of a heart condition.12-22-2011
20130131789DEVICE AND METHOD FOR BLOCKING PIPELINES, ESPECIALLY UNDER THE SEA - Transcorporal delivery system and method for valve replacement surgery that is minimally invasive.05-23-2013
20130131790METHODS OF IMPLANTING MINIMALLY-INVASIVE PROSTHETIC HEART VALVES - Expandable prosthetic heart valves for minimally invasive valve replacement are disclosed. In one preferred embodiment, an expandable prosthetic heart valve includes a support stent comprising an expandable tubular base along an inflow end and three upstanding commissure posts along an outflow end. The three commissure posts are spaced at 120 degree intervals with gaps therebetween. The prosthetic heart valve further includes a tubular flexible member having a prosthetic section and a fabric section. The prosthetic section is connected to the three commissure posts and defines three leaflets, preferably formed of pericardial tissue. The fabric section is sutured to the expandable tubular base. The tubular base may be formed with a shape memory material and is sized for deployment with an annulus of a native aortic valve. After deployment, the three commissure posts support the leaflets above the tubular base for replacing the function of the native aortic valve. In one variation, flanges may be provided on the support stent for improving attachment of the support stent to the host tissue.05-23-2013
20130144379IMPLANTABLE WIRELESS SENSOR SYSTEMS - In some embodiments, a cardiac monitoring system includes multiple sensors configured for implantation in a cardiovascular system of a user. Each sensor includes a sensing unit configured to be disposed in sensory communication with the location for measuring a biological parameter in the at least one heart chamber. The sensing unit is also configured to generate a sensory signal associated with the biological parameter. Each sensor also includes a wireless transceiver configured to receive the sensory signal from the sensing unit. The wireless transceiver is further configured to wirelessly transmit the sensory signal to an external processing device disposed outside a body of the user. The external processing device monitors, based on the sensory signal received from at least two sensors from the plurality of sensors, cardiac health associated with at least one of an implanted device or a surgery.06-06-2013
20080208328Systems and Methods For Placement of Valve Prosthesis System - Valve prosthesis systems and methods/systems for placement of such valve prostheses are provided that facilitate efficient, reliable and minimally invasive delivery modalities. The placement systems and methods permit remote manipulation and positioning of the valve prosthesis such that desirable placement relative to anatomical structures, e.g., the heart annulus, may be achieved. The valve prosthesis includes a resilient ring, a plurality of leaflet membranes mounted with respect to the resilient ring, and a plurality of positioning elements movably mounted with respect to the flexible ring. The delivery system includes a first elongate element that terminates at the valve prosthesis and is manipulable by an operator to remotely rotate the positioning elements relative to the flexible ring. A second elongate element terminates at the valve prosthesis and is manipulable by an operator to remotely advance the valve prosthesis downward into an anatomical annulus. The second elongate element may be manipulated to remotely advance the valve prosthesis into the anatomical annulus to assume a position for supporting post-implantation function of the valve prosthesis in situ. The first elongate element may be further manipulated to remotely rotate the positioning element relative to the flexible ring to cause the positioning element to engage tissue associated with the anatomical annulus and to thereby maintain the post-implantation position of the valve prosthesis in situ. Methods for valve prosthesis deployment are also provided.08-28-2008
20100286769System For Implanting a Valve Prosthesis - A valve prosthesis (11-11-2010
20100286768DELIVERY AND RETRIEVAL SYSTEMS FOR COLLAPSIBLE/EXPANDABLE PROSTHETIC HEART VALVES - A system for delivering a collapsible and re-expandable prosthetic heart valve into a patient includes a valve support structure (11-11-2010
20100286767ANNULOPLASTY RING WITH INTRA-RING ANCHORING - Apparatus is provided that includes an annuloplasty system for use on a subject. The system includes an annuloplasty ring, which includes a sleeve having a lumen, and at least one anchor, shaped so as to define a coupling head and a tissue coupling element, which tissue coupling element is shaped so as to define a longitudinal axis, and is configured to penetrate cardiac tissue of the subject in a direction parallel to the longitudinal axis. The system further includes an anchor deployment manipulator, configured to be removably positioned within the lumen of the sleeve, and, while so positioned, to deploy the tissue coupling element from a distal end of the deployment manipulator through a wall of the sleeve into the cardiac tissue in the direction parallel to the longitudinal axis of the tissue coupling element and parallel to a central longitudinal axis through the distal end of the deployment manipulator.11-11-2010
20110251683Transcatheter Prosthetic Heart Valve Delivery Device with Stability Tube and Method - A device for percutaneous delivery of a stented prosthetic. heart valve. The device includes a sheath, a handle, and an outer stability tube. The sheath includes a distal capsule and a proximal shaft. The handle has a housing maintaining an actuator mechanism that is coupled to the shaft. The actuator mechanism is configured to selectively move the shaft, and thus the capsule, relative to the housing. The stability tube is coupled to the housing and is coaxially received over the shaft such that the shaft is slidable relative to the stability tube. In a delivery state, the capsule encompasses the prosthetic valve. In a deployed state, the capsule is withdrawn from the prosthetic valve. The shaft slides relative to the stability tube in transitioning from the loaded state to the deployed state. When used with an introducer device, the stability tube frictionally isolates the sheath.10-13-2011
20110238166METHOD FOR DIRECT IMPLANTATION OF A HEART VALVE PROSTHESIS - A method for implanting a heart valve into a patient's heart can include inserting the heart valve prosthesis into a barrel of an implanter apparatus, such that the heart valve prosthesis has a reduced cross-sectional dimension relative to a fully expanded cross-sectional dimension of the heart valve prosthesis. An opening is created in muscle tissue of the patient's heart to provide a substantially direct path that extends from the opening to a desired implantation site in the heart. A length of the barrel is inserted through the opening in the tissue such that an end of the barrel and the opening are along the direct path to the implantation site. The heart valve prosthesis is advanced through the barrel to the implantation site. The heart valve prosthesis is positioned at the desired implantation site. The heart valve prosthesis can be expanded at the desired implantation site from the reduced cross-sectional dimension toward the expanded cross-sectional dimension, such that an exterior portion of the heart valve prosthesis engages adjacent tissue to mitigate movement of the heart valve prosthesis relative to the adjacent tissue.09-29-2011
20130150954FORCE-BASED HEART VALVE SIZER - A valve sizer for determining an appropriate replacement valve size when performing a heart valve replacement procedure is provided. In one version the valve sizer has a hollow shaft with proximal and distal ends. A movable sizing element couples to the distal end of the shaft and is radially expandable between first, contracted and second, expanded positions. An actuator assembly on a handle includes an actuator coupled to a clutch member via a ball-spring-detent clutch. A rod extends through the shaft and maintains a fixed distance between the handle and a distal hub in the sizing element. Movement of the actuator causes axial movement of the shaft, thereby causing radial expansion of sizing petals relative to the hub. The clutch slips when a predetermined reaction force from the surrounding valve annulus is met by the petals.06-13-2013
20130150955ACTIVE HOLDER FOR ANNULOPLASTY RING DELIVERY - An active annuloplasty ring holder having a template that can be folded or pivoted to the side allowing the template to align longitudinally with the handle and enter the patient's chest through a small incision. The holder may include a mechanism to remotely detach sutures fastening the ring to the holder, thereby detaching the ring while avoiding the risk associated with introducing a scalpel into the operating field. A detachment mechanism may include a movable pin actuated by a pull wire that releases a plurality of holding sutures, or a hot wire, knives, or pull wire that severs the sutures. The holder may have a built-in light source for better visualization of the ring inside the heart. The holder may also have an optical means of visualizing the inside of the heart from the proximal end of the handle.06-13-2013
20100292785IMPLANT FOR TREATMENT OF A HEART VALVE, IN PARTICULAR A MITRAL VALVE, MATERIAL INCLUDING SUCH AN IMPLANT, AND MATERIAL FOR INSERTION THEREOF - This implant (11-18-2010
20100292783DEVICE FOR SURGICAL INTERVENTIONS - A device for locating an operational unit within a patient's body within the framework of a minimally-invasive surgery intervention includes a shaft having a distal end carrying an operational unit. The device includes an illuminator located at the distal end of the shaft. The illuminator is selectively adjustable to provide a selectively variable lighting field in correspondence with the operational unit. The device may be, for example, a delivery system for a heart valve or a balloon device for post-dilation of such a heart valve once implanted.11-18-2010
20120283823METHODS OF IMPLANTING AN IMPLANTATION DEVICE - The implant implantation unit (11-08-2012
20130197629Inversion Delivery Device And Method For A Prosthesis - A delivery device usable to deliver an inverting implant is provided that includes a positioning mechanism that automatically initiates the inversion process once a predetermined length of the implant has exited a delivery catheter. The positioning mechanism allows the implant to be safely and accurately deployed with reduced operator experience and in a greater variety of target locations.08-01-2013
20130184811Device and Method for Replacing Mitral Valve - A prosthetic mitral valve assembly and method of inserting the same is disclosed. In certain disclosed embodiments, the prosthetic mitral valve assembly has a flared upper end and a tapered portion to fit the contours of the native mitral valve. The prosthetic mitral valve assembly can include a stent or outer support frame with a valve mounted therein. The assembly can be adapted to expand radially outwardly and into contact with the native tissue to create a pressure fit. One embodiment of a method includes positioning the mitral valve assembly below the annulus such that the annulus itself can restrict the assembly from moving in an upward direction towards the left atrium. The mitral valve assembly is also positioned so that the leaflets of the mitral valve hold the assembly to prevent downward movement of the assembly towards the left ventricle.07-18-2013
20130123914PERCUTANEOUSLY DELIVERABLE HEART VALVE AND METHODS ASSOCIATED THEREWITH - A prosthetic heart valve implantable by catheter without surgery includes a substantially “dry” membrane or tissue material. In at least one embodiment, the tissue is folded in a dry state to form a tissue leaflet assembly that is then attached to a frame to form an implantable prosthetic heart valve. Alternatively, one or more tissue leaflets are operatively associated with a frame to form an implantable prosthetic heart valve. The implantable prosthetic heart valve is subsequently pre-mounted on an integrated catheter delivery system. The catheter delivery system that includes the implantable prosthetic heart valve is then packaged and transported while the tissue remains dry. The implantable prosthetic heart valve, while remaining substantially dry, can then be implanted into the receiving patient.05-16-2013
20130123912MEDICAL DEVICE WITH NOSECONE AND NOSECONE TUBE EXTENSION - Medical device delivery systems and methods for making and using medical device delivery systems are disclosed. An example medical device delivery system may include an outer sheath. An inner catheter may be disposed within the outer sheath. The inner catheter may have a distal end. A tube extension may be coupled to the distal end of the inner catheter and may extend distally therefrom. The tube extension may include a crush resistance support member.05-16-2013
20130123910INFLATABLE MINIMALLY INVASIVE SYSTEM FOR DELIVERING AND SECURING AN ANNULAR IMPLANT - A delivery device for an annular implant that includes a balloon expansion mechanism and an annular implant having an adjustable dimension. The balloon expansion mechanism includes an inflation tube attached to a non-occluding balloon collar which is supported by trusses radially extending from a trocar. The annular implant further includes a flexible ring core, contiguous coiled spacers, and anchoring blocks. The flexible ring core is adjusted via a cinching mechanism. The anchoring blocks are spaced along the ring core by the contiguous coiled spacers, which keeps the distance between each pair of anchoring blocks equidistant as the ring core diameter is manipulated by the device user. The annular implant can also include gunbarrel elements housed in the trocar. Each gunbarrel element contains a gunbarrel pusher which drives an attachment element into the annular implant and annular tissue.05-16-2013
20130190859SYSTEM FOR LOADING A COLLAPSIBLE HEART VALVE - An assembly for collapsing a self-expanding prosthetic heart valve includes a compression member, a support member and a constricting member. The compression member has a tapered wall between its first open end and its second open end, the tapered wall defining an open space adapted to receive the valve. The support member has a base and a recess adapted to receive an end of the valve. The support member and the compression member are movable toward one another to compress the valve and push it through a relatively small aperture in the second open end of the compression member. The second end of the constricting member is sized to receive the compressed valve from the second open end of the compression member for loading into a delivery device.07-25-2013
20120029629MITRAL CERCLAGE ANNULOPLASTY APPRATUS - A mitral cerclage annuloplasty apparatus comprises a tissue protective device and a knot delivery device. The tissue protective device comprises a first protective tube and a second protective tube. The knot delivery device comprises a tube wherein a loose knot is looped around its distal end through a hole and wherein tight knot is formed when the distal end of the tube is cut open. Alternatively, the knot delivery device comprises an inner tube and outer tube. The inner tube is insertable and rotatable inside the outer tube. When the tubes are in a closed position by rotating either the outer tube or the inner tube, a hole is created near its distal end. When the tubes are in open position by rotating either the outer tube or the inner tube, the hole joins the opening of the outer tube and lengthens.02-02-2012
20120029628METHOD OF RESHAPING A VENTRICLE - Methods for restoring the conical shape of a dilated heart ventricle, or at least reshaping the ventricle to a more conical shape to counter the effects of dilation, thereby improving pumping efficiency. In an exemplary embodiment, a reshaping apparatus comprises an implantable body that can be delivered to a dilated left ventricle via the patient's vasculature in a minimally-invasive procedure. When deployed inside the left ventricle, the body is adapted to apply a longitudinal (downward) force against the inner surface of the left ventricle that causes the ventricle to distend or elongate downwardly relative to the base of the heart so as to at least partially restore the conical shape of the heart. In other embodiments, one or more tension members can be secured to heart tissue inside a heart chamber or on the outside of the heart and placed in tension to reshape the geometry of the heart.02-02-2012
20120029627Methods and Apparatus for Endovascular Heart Valve Replacement Comprising Tissue Grasping Elements - The present invention provides an apparatus for endovascularly replacing a patient's heart valve. In some embodiments, the apparatus includes an expandable anchor supporting a replacement valve, the anchor and replacement valve being adapted for percutaneous delivery and deployment to replace the patient's heart valve, the anchor having a braid having atraumatic grasping elements adapted to grasp tissue in a vicinity of the patient's heart valve.02-02-2012
20120041547Heart Valve Delivery Catheter With Safety Button - Valve delivery catheter assemblies including components that limit trauma to the expanded prosthetic valve and body channels as the distal tip of the catheter is withdrawn through the expanded valve and thereafter from the body. Catheter assemblies according to the present invention can include a handle assembly, an introducer sheath, and a distal tip assembly. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. A safety button can be included on the handle assembly to allow for precise and consistent positioning of the prosthetic valve in the body. A valve retaining mechanism can be included to assist in retaining the prosthetic valve prior to deployment.02-16-2012
20130204357Stentless Support Structure - A stentless support structure capable of being at least partly assembled in situ. The support structure comprises a braided tube that is very flexible and, when elongated, becomes very long and very small in diameter, thereby being capable of placement within a small diameter catheter. The support structure is preferably constructed of one or more thin strands of a super-elastic or shape memory material such as Nitinol. When released from the catheter, the support structure folds itself into a longitudinally compact configuration. The support structure thus gains significant strength as the number of folds increase. This radial strength obviates the need for a support stent. The support structure may include attachment points for a prosthetic valve.08-08-2013
20130204356Transcatheter Valve Delivery Systems and Methods - Delivery devices and methods for percutaneously delivering a prosthetic valve to the heart of a patient. These prosthetic valves may be configured to provide complimentary features that promote optimal placement of the prosthetic valve in a native heart valve, such as the aortic valve, mitral valve, pulmonic valve, and/or tricuspid valve. The delivery device includes a release sheath assembly housed within an outer delivery sheath. A release sheath component of the assembly captures a portion of the prosthetic valve to the delivery device, and effectuates complete release of the prosthetic valve with retraction of the outer sheath.08-08-2013
20120078350RETAINERS FOR TRANSCATHETER HEART VALVE DELIVERY SYSTEMS - A delivery device for an implantable medical device having at least one retention member at an end thereof includes a shaft extending in a longitudinal direction, an elongated sheath surrounding a longitudinal portion of the shaft, a compartment defined inside of the sheath and adapted to receive the medical device in an assembled condition, a retainer positioned at one end of the compartment, and at least one acceptance in the retainer adapted to receive the retention member of the medical device in the assembled condition. The sheath is slidable relative to the shaft in the longitudinal direction to uncover and deploy the medical device. The retainer may be rotatable relative to the shaft to reduce torsional forces in the medical device during delivery and deployment. The retainer may have at least one recess facing the compartment for receiving a strut at an end of a stent of the medical device.03-29-2012
20120083874DEVICE FOR COLLAPSING AND LOADING A HEART VALVE INTO A MINIMALLY INVASIVE DELIVERY SYSTEM - A device is provided for collapsing a stented bioprosthetic valve, including first section and second sections, each spanning between first and second ends of the device. The second section of the device is associated with the first section to at least partially enclose an internal cavity formed by the first and second sections, the internal cavity tapering from an open insertion portion at a first end of the device to an open exit portion at a second end of the device. The insertion portion has a larger dimension than the exit portion. When the first section and second section are substantially enclosing the internal cavity, a stented bioprosthetic valve may be inserted into the insertion portion and collapsed as it is moved toward and through the exit portion. The valve may then be loaded on an apparatus for insertion into the body.04-05-2012
20130211508SEQUENTIALLY DEPLOYED TRANSCATHETER MITRAL VALVE PROSTHESIS - A sequentially deployed prosthetic cardiac valve includes a self-expanding frame having an atrial skirt, a ventricular skirt, and an annular region disposed therebetween. A first anterior tab is disposed on an anterior portion of the frame. A posterior tab is on a posterior portion of the self-expanding frame. The frame may be designed so that any portion may expand sequentially in any desired order. For example, a portion of the first anterior tab and a portion of the posterior tab may partially self-expand first. Next, the first anterior tab may fully self-expand before the posterior tab fully self-expands. The posterior tab may fully self-expand next followed by the ventricular skirt, or the ventricular skirt may self-expand next followed by full expansion of the posterior tab.08-15-2013
20130211509METHOD FOR IMPLANTING PROSTHETIC VALVE - A method for implanting a prosthetic valve apparatus in a novel location which replaces the function of a native diseased valve after an Alfieri procedure. The prosthetic valve apparatus includes a one way valve and an expandable valve seating. anchoring and securing apparatus in a newly created orifice near or at the center of the anterior valve leaflet. The prosthetic valve apparatus also causes the sealing of the native valve and thus results in a solution for paravalvular leakage and regurgitation.08-15-2013
20130211510METHODS AND DEVICES FOR TRANSCATHETER CERCLAGE ANNULOPLASTY - Devices, apparatus, and methods for catheter-based repair of cardiac valves, including transcatheter-mitral-valve-cerclage annuloplasty and transcatheter-mitral-valve reapposition. In particular, a target and capture device is provided for guiding a cerclage traversal catheter system through a cerclage trajectory, particularly through a reentry site of the cerclage trajectory. The target and capture device provides the user with a target through which the cerclage traversal catheter system must be guided, particularly under imaging guidance, so as to properly traverse the cerclage trajectory at any desired location, particularly at a reentry site. The target and capture device can, further, ensnare and externalize the cerclage traversal catheter system.08-15-2013
20100087928Elbow Prosthesis - An elbow prosthesis constructed in accordance to one example of the present teachings can include a capitellar implant having an articulating head and a stem. The articulating head can have a first articulating surface positioned generally between a lateral side and a medial side. A passage can extend through the articulating head from the lateral side to the medial side. The articulating head can define a counterbore formed at the lateral side and that is concentric with the passage. According to other features, the elbow prosthesis can include a coronoid implant that has a body and a stem. The body can have a superior articulating surface that includes a central ridge and an anterior buttress. The central ridge can be configured to accommodate articulation with a trochlea in an implanted position.04-08-2010
20110125274ELBOW REPLACEMENT APPARATUS AND METHODS - Apparatus and methods for total elbow replacement are provided to allow a surgeon to intraoperatively select a linked or unlinked constraint by utilizing a connection located on the body of the ulnar and/or humeral stem. Additional modularity also allows the selection of a cemented or cementless stem as described herein. The modularity and adjustability provides a number of advantages.05-26-2011
20120109323Modular Prosthesis And Use Thereof For Replacing A Radial Head - A tool provides for coupling a first prosthetic to a second prosthetic. The tool can include a first arm having a first concave bearing surface configured to apply a force in a first direction. The tool can also include a second arm having a hook shaped member. The hook shaped member can have a second concave bearing surface configured to apply a force in a second direction opposite the first direction. The first arm and the second arm can be generally parallel, and the first arm can be translatable with respect to the second arm. The tool can include a translation force mechanism, which can apply force to the first arm and the second arm so as to cause generally parallel translation of the first arm and second arm.05-03-2012
20110172781ELBOW PROSTHESIS - An elbow prosthesis can include a capitellar implant that has an articulating head and a stem. The articulating head can have a first substantially hemispherical portion and a second portion that collectively extend between lateral and medial sides of the articulating head and are separated by a plane. The first and second portions can generally extend between the lateral and medial sides. The second portion can generally have an attachment lobe that extends on the lateral side and that defines a passage therethrough. The passage can extend at least partially on the second portion.07-14-2011
20120290099MINIMALLY INVASIVE SURGICAL TOOLS FOR HIP PROSTHESIS - Instrumentation for a modular prosthesis having a stem and a neck comprises a handle and an adaptor. The handle extends along an axis. The handle has a distal end and a proximal end. The proximal end has a blunt surface configured to be struck. The adaptor has a male end configured to mate inside the bore of the stem. The adaptor further has a surface configured to mate with the distal end of the handle. The adaptor is configured to have a medial portion and a lateral portion. The medial portion has a relief such that the adaptor is configured to disengage the stem when the adaptor is rotated relative the stem.11-15-2012
20080288079Radial Head Implant and Related Instrument - A radial head implant including a head, a stem, and a locking mechanism, whereby the head laterally engages the stem, and an instrument for implanting and removing such implant is described.11-20-2008
20090024221MODULAR TOTAL ELBOW PROSTHESIS, HUMERAL COMPONENT AND ASSOCIATED KIT - An ulnar assembly for use with a humeral component to form an elbow prosthesis is provided. The ulnar assembly includes a first component including a portion thereof defining a stem for implantation in a cavity formed in the ulna. The first component defines a longitudinal axis thereof generally coincident with the longitudinal axis of the ulna. The ulnar assembly also includes a second component attached to the first component. The second component is attachable and removable from the first component along the longitudinal axis of the first component. One of the first component and the second component include an external taper. The other of the first component and the second component defines an internal taper therein adapted to receive the external taper.01-22-2009
20090281632ULNAR HEAD PROSTHESIS SYSTEM - An ulnar prosthesis assembly comprising a head formed with a curved surface extending between opposed ends and a stem. One of the ends of the head has an attachment bore defined therein. The attachment bore generally has a first diameter and includes an attachment groove thereabout with a second diameter greater than the first diameter to define at least one attachment shoulder. The stem has a stem body extending between a proximal end configured for implantation in a target bone and a distal end configured to be received in the attachment bore. The distal end has a locking flange extending radially therefrom. The locking flange defines a locking shoulder having a diameter greater than the first diameter such that upon receipt in the attachment bore, the locking shoulder engages the attachment shoulder.11-12-2009
20110144759MODULAR PROSTHESIS AND USE THEREOF FOR REPLACING A RADIAL HEAD - A modular prosthesis system for replacement of a head portion of a proximal radius includes a monolithic stem component, a head component, and a locking mechanism formed by the stem and head components. The stem component defines a stem anchoring portion having a longitudinal axis and configured to couple to the proximal radius, and a dovetail-shaped first mounting portion on a first end face that extends in a first direction transverse to the longitudinal axis. The head component has a dovetail-shaped second mounting portion on a second end face opposite the first end face slidably engaged with the first mounting portion along the first direction. One of the first and second mounting portions intersects the longitudinal axis. The locking mechanism is formed at an interface between the stem and head components and is engaged through relative translational movement between the stem and head components. A related method is provided.06-16-2011
20110230972ELBOW RESURFACING PROSTHESIS - A method and apparatus for replacing a selected portion of the anatomy is described. In particular, a prosthesis can be provided to replace a portion of an articulating joint, such as an elbow. The apparatus can be modular for various reasons and each of the modular portions can include a different dimension to achieve a selected result.09-22-2011
20100262251HIGH MODULUS CROSSLINKED POLYETHYLENE WITH REDUCED RESIDUAL FREE RADICAL CONCENTRATION PREPARED BELOW THE MELT - The present invention provides an irradiated crosslinked polyethylene containing reduced free radicals, preferably containing substantially no residual free radical. Disclosed is a process of making irradiated crosslinked polyethylene by irradiating the polyethylene in contact with a sensitizing environment at an elevated temperature that is below the melting point, in order to reduce the concentration of residual free radicals to an undetectable level. A process of making irradiated crosslinked polyethylene composition having reduced free radical content, preferably containing substantially no residual free radicals, by mechanically deforming the polyethylene at a temperature that is below the melting point of the polyethylene, optionally in a sensitizing environment, is also disclosed herein.10-14-2010
20100262252MODULAR PROSTHESIS AND USE THEREOF FOR REPLACING A RADIAL HEAD - A modular prosthesis system for replacement of a head portion of a proximal radius includes a monolithic stem component, a head component, and a locking mechanism formed by the stem and head components. The stem component defines a stem anchoring portion having a longitudinal axis and configured to couple to the proximal radius, and a dovetail-shaped first mounting portion on a first end face that extends in a first direction transverse to the longitudinal axis. The head component has a dovetail-shaped second mounting portion on a second end face opposite the first end face slidably engaged with the first mounting portion along the first direction. One of the first and second mounting portions intersects the longitudinal axis. The locking mechanism is formed at an interface between the stem and head components and is engaged through relative translational movement between the stem and head components. A related method is provided.10-14-2010
20100234960Articulating Implant System - An articulating implant system is provided for fixation to a bone. The articulating implant system includes a fixation component for fixation to the bone and an articulating member for articulating against bone or cartilage. Specifically, a modular ulnar implant is provided in accordance with the articulating implant system of the present invention wherein the fixation component is a stem for insertion into the intramedullary canal of the distal ulna and the articulating member is a head for articulating with the radial sigmoid notch.09-16-2010
20100222887Elbow Prosthesis - An elbow prosthesis constructed in accordance to one example of the present teachings can include a first stem structure that is operable to be positioned in a first bone of a joint. The first stem structure can include a first stem portion and a cage structure. The first stem portion may be operable to be positioned in the first bone. The cage structure can be formed generally between an inner sidewall and an outer surface. The stem portion can have opposing surfaces that define a disconnect formed entirely through the cage structure from the inner sidewall to the outer surface. A first bearing component can have an exterior cage opposing surface. The first bearing component can be selectively inserted into the cage structure from an insertion position to an installed position. A fastener can be threadably advanced into an engaged position with the cage structure to reduce a gap defined between the opposing surfaces of the disconnect while radially contracting the cage structure around the first bearing.09-02-2010
20090105839Artificial elbow joint - An artificial elbow joint including a humeral component made of metal and an ulnar component made of resins for replacing an elbow joint. The humeral component of this artificial elbow joint is configured by a substantially cylindrical trochlea and a stem extending from the trochlea that is inserted into the humeral; and the ulnar component is configured by a joint surface member which receives the trochlea of humeral component in a rotatable manner and a stem which extends from the joint surface member and is inserted into the ulna. The stem of the humeral component is curved gently downward overall so as to comply with the lordotic shape of the humeral, and the trochlea is turnable about the centerline of the stem.04-23-2009
20090036991Radial Head Replacement System - A radial head replacement system includes a radial head replacement, an apparatus for guiding the resection of a radial head, and a kit including bone plug and bone plug insertion instrument. The radial head replacement has a separate adjustable head portion that may be secured on an implanted stem such that the implanted radial head replacement smoothly interfaces with the capitellum of the humerus. In another form, the radial head replacement uses crossed bone screws that serve to more securely anchor the stem of the radial head replacement in the intramedullary canal of the radius. The resection guide includes a movable cutting guide which ensures a precise resection of the radial head and thereby allows for better positioning of the implanted radial head replacement. The bone plug limits the travel of bone cement beyond the area of affixation of the stem portion of a radial head replacement to the radius.02-05-2009
20110035016ALIGNABLE PROSTHESES DEVICE, SYSTEM AND METHOD - A prosthesis is provided for replacing a portion of a bone making up a joint. The prosthesis is adapted, intraoperatively, to optimize the anatomical alignment of the prosthesis in the joint. In particular, a jig is used to identify the axis of rotation of the joint intraoperatively and to align a portion of the prosthesis with the identified axis. The angle of the head of the prosthesis is adjusted to optimize contact with the appropriate corresponding portions of the joint, at which point the position of the head is fixed to prevent further rotation of the head relative to the remainder of the prosthesis.02-10-2011
20090312839LATERAL ELBOW PROSTHESIS - PROXIMAL RADIOULNAR JOINT - A proximal radioulnar joint (lateral elbow) prosthesis includes an ulnar brace member to be secured to the outer surface of the ulna bone. The ulnar brace member defines a bearing surface for supporting the radius. The prosthesis may also include a radial brace member which cooperates with the ulnar brace member.12-17-2009
20110125276MODULAR PROSTHESIS AND USE THEREOF FOR REPLACING A RADIAL HEAD - A modular prosthesis system for replacement of a head portion of a proximal radius includes a monolithic stem component, a head component, and a locking mechanism formed by the stem and head components. The stem component defines a stem anchoring portion having a longitudinal axis and configured to couple to the proximal radius, and a dovetail-shaped first mounting portion on a first end face that extends in a first direction transverse to the longitudinal axis. The head component has a dovetail-shaped second mounting portion on a second end face opposite the first end face slidably engaged with the first mounting portion along the first direction. One of the first and second mounting portions intersects the longitudinal axis. The locking mechanism is formed at an interface between the stem and head components and is engaged through relative translational movement between the stem and head components. A related method is provided.05-26-2011
20110125275PROSTHETIC CONDYLAR JOINTS WITH ARTICULATING BEARING SURFACES HAVING A TRANSLATING CONTACT POINT DURING ROTATION THEREOF - A prosthetic joint according to the present invention includes a first implant component for attachment to a first bone and a second implant component for attachment to a second bone. The first implant component has a condylar portion that includes first and second condylar bearing surfaces and similarly, the second implant component has bearing surfaces that receive and are complementary to the first and second condylar bearing surfaces. Each of the first and second condylar bearing surfaces and each of the bearing surfaces of the second implant component has a cross-section in a coronal plane that exhibits two different radii and a contact point is established between the first and second condylar bearing surfaces and the bearing surfaces of the second implant component. The bearing surfaces of the respective implant components are configured such that varus and valgus rotation of the first implant component relative to the second implant component causes the contact point to move outwardly.05-26-2011
20090312840PROSTHETIC ELBOW REPLACEMENT - A prosthetic elbow replacement includes a humeral component having a stem dimensioned to fit within a medullary canal of the humerus and having a yoke connected to the stem wherein the yoke terminates in spaced apart arms. A pivot pin is mounted between the arms for rotational movement with respect to the humeral component. The pivot pin has a transverse throughhole. There is an ulnar component having an ulnar stem including a distal end dimensioned to fit within a medullary canal of the ulna and an opposite proximal end dimensioned to fit within a first end opening of the throughhole. The ulnar component has a mounting cap dimensioned to fit within a second end opening of the throughhole. A fastener connects the ulnar stem and the mounting cap such the proximal end of the ulnar stem is positioned within the first end opening of the throughhole and the mounting cap is positioned within the second end opening of the throughhole. The pivot pin rotates to allow for flexion of the prosthetic elbow replacement, and also allows for axial rotation of the ulna component in the humeral component.12-17-2009
20100241236Modular Radial Head Prosthesis - A prosthesis system for replacement of a head portion of a proximal radius can include an articulation component having a first connection portion. A first head component can have a second connection portion that connects to the first connection portion. A second head component can have a third connection portion that connects to the first connection portion. The second head component can have a distinct dimension from the first head component. A stem component can include a fourth connection portion that connects with either of the first or second head components. The stem component can have a stem anchoring portion that connects to the radius.09-23-2010
20090281631ULNAR HEAD PROSTHESIS SYSTEM - An ulnar prosthesis assembly comprising a head formed with a curved surface extending between opposed ends and a stem. One of the ends of the head has an attachment bore defined therein. The attachment bore generally has a first diameter and includes an attachment groove thereabout with a second diameter greater than the first diameter to define at least one attachment shoulder. The stem has a stem body extending between a proximal end configured for implantation in a target bone and a distal end configured to be received in the attachment bore. The distal end has a locking flange extending radially therefrom. The locking flange defines a locking shoulder having a diameter greater than the first diameter such that upon receipt in the attachment bore, the locking shoulder engages the attachment shoulder.11-12-2009
20100030339METHOD AND APPARATUS FOR ADJUSTING HEIGHT AND ANGLE FOR A RADIAL HEAD - A modular prosthesis system for replacement of a head portion of a radius. The prosthesis system includes a head component having a first connection portion that connects to a second connection portion and a collar component having the second connection portion and a third connection portion. The system also includes a stem component including a fourth connection portion that connects with the third connection portion, the stem component having a stem anchoring portion that connects to the radius. The collar component provides the modular geometry to the prosthesis without having to have an increased number of head components and stem components with variable lengths and angles.02-04-2010
20110166663LATERAL ELBOW PROSTHESIS - PROXIMAL RADIOULNAR JOINT - A proximal radioulnar joint (lateral elbow) prosthesis includes an ulnar brace member to be secured to the outer surface of the ulna bone. The ulnar brace member defines a bearing surface for supporting the radius. The prosthesis may also include a radial brace member which cooperates with the ulnar brace member.07-07-2011
20120059483ORTHOPEDIC INTERFACE DEVICE AND METHOD - An orthopedic joint implant component and implant component surface are disclosed. The implant component can have a resilient or compliant structure to distribute force loads. The implant component surface can be attached by one or more springs or other resilient or compliant elements to the remainder of the implant. Methods of using the component and component surface are also disclosed.03-08-2012
20120071985IMPLANT POSITIONING SYSTEMS AND ASSOCIATED METHODS - A system for securing a prosthesis in a bone includes a reference anchor for insertion into a cavity of a bone to define a reference point during prosthesis implantation, the reference anchor including a body having a mating feature and a gripping projection for engaging an inner surface of the bone cavity. The system also includes a stem having a terminal end adapted to mate with the engagement feature of the reference anchor such that the stem is disposed at a desired position relative to the reference point.03-22-2012
20120136450ELBOW JOINT PROSTHESIS AND METHOD FOR IMPLANTATION - A modular elbow prosthesis is disclosed, as well as a surgical approach and implantation technique, for using the prosthesis. The system is the first and only to allow for a, Biomechanically Anatomical, Nonconstrained, Compartmental (BANC) Elbow Arthroplasty. The modularity of the system allows it to be implanted as an unicompartmental or partial elbow replacement or a total elbow replacement. The modular elbow prosthesis for partial elbow replacement includes a cylindrical medial humeral component, a polyethylene ring thereon, and a semicircular medial ulnar component which mates with the polyethylene ring. Additionally, for total elbow replacement, the modular elbow prosthesis also includes a circular lateral humeral component, a polyethylene ring thereon, a semicircular lateral ulnar component, and a radial component. Implantation of the prosthesis is through a minimally invasive medial surgical approach with the aid of precision biomechanical guides. The application is well suited for canines, other quadrupeds, and people.05-31-2012
20120083892Modular Radial Head Prostheses - According to various embodiments, provided is a prosthesis system for replacement of a head portion of a proximal radius. The system can include a first polymeric articulation component having a first locking portion and a metal head component having a second locking portion. The second locking portion can mate with the first locking portion to form a first locking mechanism to initially couple the first articulation component to the head component. The head component can define a locking channel. The system can also include a stem component having a protrusion receivable in the locking channel. The protrusion can define a bore, and the stem component can be adapted to be coupled to the radius. The system can also include a fastener received through the locking channel and into the bore to provide a second locking mechanism that couples the head component to the stem component.04-05-2012
20130103158IMPLANTABLE ELBOW JOINT ASSEMBLY WITH SPHERICAL INTER-SUPPORT - A multi-component elbow joint assembly incorporated into reconditioned end surfaces established between an upper humerus bone and opposing lower radius and ulna bones. The assembly includes a first component anchored into the upper humerus reconditioned end surface and exhibits a first exposed support surface. A second component is anchored into the lower reconditioned bone end surface of at least one of the radius and ulna bones and exhibits a second exposed support surface. An intermediate component is supported in at least one of eccentric or rotational fashion between the first and second anchored components.04-25-2013
20130178944Ulnar Head Implant - The present teachings provide an ulnar head implant. The implant can include a head component adapted to articulate with a portion of the anatomy. The head component can define a coupling bore through a surface. The implant can also include a stem component having a base and a post that extends from the base for insertion into a prepared portion of an anatomy. The base can include a coupling feature. The implant can include an intermediate component receivable within the coupling bore and couplable to the coupling feature to couple the head component to the stem component.07-11-2013
20130144395ELBOW ASSEMBLY FOR SURGICAL DEVICES - Surgical devices are disclosed herein that generally include an intracorporeal elbow joint to facilitate translational movement of an end effector while allowing a body portion of the surgical device and a trocar or working channel through which the device is inserted to be maintained in a fixed angular orientation relative to the patient. This allows a plurality of such devices to be used effectively with a single incision or access device. Such devices also generally provide end effector movement with six degrees of freedom, while maintaining a mechanical linkage between the user and the end effector and while mimicking and/or mirroring natural user movement. Various methods related to such devices are also disclosed.06-06-2013

Patent applications in class Combined with surgical tool