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Stent structure

Subclass of:

623 - Prosthesis (i.e., artificial body members), parts thereof, or aids and accessories therefor

623100100 - ARTERIAL PROSTHESIS (I.E., BLOOD VESSEL)

Patent class list (only not empty are listed)

Deeper subclasses:

Class / Patent application numberDescriptionNumber of patent applications / Date published
623100160 Having multiple connected bodies 317
623100200 Self-expanding stent 78
623100220 Helically wound 48
623100180 Having shape memory 40
623100170 Stent length remains constant with lateral expansion 16
623100210 Formed inside natural blood vessel 2
20130204351Aneurysm Graft Devices And Methods - The present invention provides methods and apparatus for the endoluminal positioning of an intraluminal prosthesis at a target location within a body lumen. The device may comprise a porous, multi-layer prosthesis that can include several different tubular mesh components such as an everted tubular component, an tubular component that expands to various different sizes, a bifurcated tubular component, and a tubular component with an undulating expanded shape, among others. Various components can have different densities or pore sizes and can be overlaid on each other to selectively block different regions of a vessel.08-08-2013
20130211500Liquid Cast Biodegradable Arterial Stent - Disclosed are liquid cast biodegradable arterial stents and methods for preparing liquid cast biodegradable arterial stents. The typically includes a biodegradable polymer and may include an agent for treating neointimal hyperplasia.08-15-2013
Entries
DocumentTitleDate
20130030516INTRAVASCULAR STENTS - Stent designs for use in vessels, such as the carotid and coronary arteries, are disclosed. The stents consist of a plurality of radially expandable cylindrical elements generally aligned on a common longitudinal stent axis and interconnected by one or more interconnecting members placed so that the stent is flexible in a longitudinal direction. The cylindrical elements form a generally serpentine wave pattern transverse to the longitudinal axis between alternating valley portions and peak portions. The interconnecting members are attached to the double-curved portions to connect a cylindrical element to an adjacent cylindrical element and interconnecting members are attached to the inverted double-curved portions to connect the cylindrical element to the other adjacent cylindrical element. The stent designs include both a six crown and an eight crown stent which exhibit flexibility and sufficient radial strength to support the vessel.01-31-2013
20090018640Dual Taper Stent Protector - A dual taper stent protector having a first stent covering region configured to cover a stent without substantially engaging the stent, a second covering region, and an engagement region for engaging a product mandrel removably disposed within a catheter shaft, and first and second tapered regions connecting the first stent covering region and the second stent covering region and the second covering region and the engagement region respectively, and to methods of making and using the same.01-15-2009
20130085564MODIFIED SCAFFOLDS FOR PERIPHERAL APPLICATIONS - Stent scaffolds that include a polymeric structure or structures bonded to the scaffold and extending along their length are disclosed. The polymeric structure extends across some or all of the gaps in struts along the length of the scaffold. Segmented scaffolds are also disclosed that include two or more axial segments arranged end to end not connected by link struts.04-04-2013
20130085563RUBBER TOUGHENED BIORESORBABLE POLYMER PERIPHERAL SCAFFOLDS - Bioabsorbable scaffolds are disclosed with a rigid polymer component and a rubbery polymer component. The rubbery polymer component is miscible, partially miscible, or immiscible with the rigid polymer component.04-04-2013
20090192588BIODEGRADABLE DOUBLE STENT - A biodegradable double stent is used for various organs such as a biliary tract, an esophagus, an airway and a ureter. A biodegradable stent having a hollow cylindrical body woven out of a separate wire made of biodegradable polymer so as to have a plurality of rhombic spaces is fixed to an intermediate portion of a primary stent having a cylindrical body. When administered into the organ, the biodegradable stent has its original function of expanding the organ, and is firmly supported in the inner wall of a narrowed passage of the organ by pressurizing the inner wall of the narrowed passage of the organ. After a predetermined time period has elapsed, the biodegradable stent is gradually degraded away by bodily fluids, thereby enabling the primary stent to be easily removed from the organ.07-30-2009
20090192587RADIO-OPAQUE ENDOPROSTHESIS - An endoprosthesis furnished with an armature made of metal wires visible in X-ray medical imaging in which the armature is formed of at least two layers of wires, the wires forming the armature comprising a core made of a radio-opaque material, the interaction between the cores of the wires of the various layers improving the visibility of the said endoprosthesis in X-ray medical imaging.07-30-2009
20110196474MAGNETICALLY SENSITIVE DRUG CARRIERS FOR TREATMENT OR TARGETED DELIVERY - Compositions of matter comprising a magnetically sensitive drug carrier and a related drug as well as methods for administering these compositions and causing them to localize within the patient using an internal or external magnetic field are described.08-11-2011
20100076544BIODEGRADABLE VASCULAR SUPPORT - The embodiments described herein are directed to biodegradable stents comprising an inner biodegradable metal scaffold and an outer polymeric coating. The biodegradable coating consists preferentially of biodegradable polymers and may additionally include at least one pharmacologically active substance such as an anti-inflammatory, cytostatic, cytotoxic, antiproliferative, anti-microtubuli, antiangiogenic, antirestenotic (anti-restenosis), antifungicide, antineoplastic, antimigrative, athrombogenic and/or antithrombogenic agent.03-25-2010
20120245673STENT AND STENT DELIVERY SYSTEM FOR SIDE-BRANCH LOCATIONS IN A CONDUIT - A stent includes a substantially cylindrical segment which is deployed in the renal vessel and a flared segment which is deployed in ostial and aortic regions of the vessel. The substantially cylindrical segment provides superior radial strength for maintaining dilated diameter of the renal vessel. The flared segment, which is formed by plurality of slits extending through the sidewall of the stent, expands to conform to the ostial and aortic regions of the vessel. The flared segment can be balloon dilated to enhance conformance of the flared stented segment to the ostial and aortic regions. A stent delivery system capable of delivering and deploying the substantially cylindrical segment and the flared segment is also disclosed.09-27-2012
20130079865IMPLANT AND METHOD FOR MANUFACTURING THE SAME - An implant comprising a perforated, preferably hollow-cylindrical basic structure which has at least one section, wherein in each section at least one strut is arranged. In order to achieve a more homogenous coverage of the wall of the treated vessel, a good interlock with the wall of the treated body cavity and a better distribution of the mechanical stresses and elongations, the strut has a multiplicity of identical, simple and interconnected elements, the basic shape of which is substantially similar to the shape of base line elements of an imaginary first order base line which likewise runs in the section, wherein the imaginary first order base line represents a reference line for the arrangement of the elements and the elements are not more than half the size of the base line elements.03-28-2013
20090118812ENDOPROSTHESIS COATING - A method includes: providing a substrate, depositing a ceramic and an extractable material onto the substrate, forming a porous structure in the ceramic by removing the extractable material, and utilizing the ceramic in an endoprosthesis. An endoprosthesis, such as a stent, including a coating formed of a ceramic and an extractable material that can be removed from the coating to form voids is also disclosed.05-07-2009
20130041454Sensor Actuated Stent - The invention is an implantable medical device to expand a vascular lumen into various positions, internally or from a remote location. The device is designed as a stent having a framework for radial or longitudinal expansion, including one or more integrated shape memory materials. The shape memory materials, or halos, radially expand to fix the framework into a first radial position. Sensors integrated with the framework mechanically or electro-mechanically monitor and control the positioning of the framework to a fixed second position, or gradually expand the framework to various radial positions. Visualization and communications devices assist in the monitoring and controlling mechanisms to position the implantable device during surgery or catherization, post-surgery, or at follow-up. The device is biocompatible, alleviating complications. The device can be utilized as a substitute, or in combination with another stent. Devices may be utilized in cardiovascular, neurovascular surgery or other intervention.02-14-2013
20130041455IMPLANT MADE OF A BIODEGRADABLE MAGNESIUM ALLOY - The present invention relates to implants made of a biodegradable magnesium alloy. The inventive implant is made in total or in parts of a biodegradable magnesium alloy comprising: 02-14-2013
20080208316Artificial Vascular Prosthesis - A vascular prosthesis having a tubular structure is provided. The tubular structure is fabricated from at least two layers wherein at least one layer includes a thrombogenic agent.08-28-2008
20100042204Stent Coating For Eluting Medication - A vascular stent comprising a drug-eluting outer layer of a porous sputtered columnar metal having each column capped with a biocompatible carbon-containing material is described. This is done by placing the stent over a close-fitting mandrel and rotating the assembly in a sputter flux. The result is a coating that is evenly distributed over the outward-facing side of the stent's wire mesh while preventing the sputtered columnar coating from reaching the inward facing side where a smooth hemocompatible surface is required. The stent is then removed from the mandrel, exposing all surfaces, and finally coated with a layer of carbon such as amorphous carbon or diamond-like carbon. The carbonaceous coating enhances biocompatibility without preventing elutriation of a therapeutic drug provided in the porosity formed between the columnar structures. The result is a stent that is adapted to both the hemodynamic and the immune response requirements of its vascular environment.02-18-2010
20100042203Self-Expanding Stent - The stent of this invention is a self-expanding stent created by a scaffolding lattice. The stent may be made from a nickel-titanium alloy. The lattice is formed from two different types of helices that proceed circumferentially in opposite directions along the longitudinal axis of the stent. The helices have no free ends. The first type of helix is formed by a series of undulations and the second type of helix is formed from a series of connection elements. The undulations may be in a zigzag or sinusoidal pattern. The connection elements connect the junction points lying on adjacent turns of the first type of helix. The junction points are formed by the ascending and descending arms of the undulations or zigzags. The ends of the stent may be formed by a closed circumferential element which is linked by connection elements to a transition zone. The transition zone is formed by a closed loop that connects directly to the first helix. The amplitude of the undulations or zigzags forming the transition zone increases from the closed loop to the point connecting the transition zone with the first type of helix. The closed circumferential element may be made from a radiopaque material. The scaffolding lattice design of the stent provides a stent having a high degree of flexibility as well as radial strength.02-18-2010
20100042202COMPOSITE STENT HAVING MULTI-AXIAL FLEXIBILITY - Composite stent structures having multi-axial flexibility are described where the composite stent may have one or more layers of bioabsorbable polymers fabricated with the desired characteristics for implantation within a vessel. A number of individual ring structures separated from one another may be encased between a base polymeric layer and an overlaid polymeric layer such that the rings are coupled to one another via elastomeric segments which enable the composite stent to flex axially and rotationally along with the vessel. Each layer may have a characteristic that individually provides a certain aspect of mechanical behavior to the composite stent such that the aggregate layers form a composite polymeric stent structure capable of withstanding complex, multi-axial loading conditions imparted by an anatomical environment such as the SFA.02-18-2010
20090157166Medical Devices Having Porous Component For Controlled Diffusion - According to an aspect of the present invention, implantable or insertable medical devices are provided which contain the following: (a) substrate having one or more depressions that contain at least one therapeutic agent and (b) a porous membrane disposed over the substrate and the one or more depressions, which regulate transport of chemical species between the therapeutic-agent-containing depressions and the exterior of the device. The substrate and the porous membrane are formed of different materials each with a different thermal expansion coefficient. Moreover, one of the substrate and the porous membrane at least partially surrounds the other. Other aspects of the present invention are directed to methods of making such medical devices, and methods of treatment using such medical devices.06-18-2009
20100106240Systems and Methods for Aneurysm Treatment and Vessel Occlusion - A system for treating an aneurysm includes an expandable barrier positionable to bridge an aneurysm neck. The barrier may comprise a fiber mesh, a balloon or a molly anchor member, and may unroll, unfold, or inflate from a compact configuration to an expanded configuration. Expansion of the barrier may be greater radially than axially. A vaso-occlusive member comprising a coil or balloon may be deposited in the aneurysm. Another aneurysm treatment system comprises an outer fenestrated stent and/or an inner fenestrated sleeve, which may be implanted together adjacent an aneurysm neck to regulate blood flow to the aneurysm. The sleeve may be movable relative to the stent to open or occlude the fenestrations, which may vary in size, shape, and distribution. An intra-luminal vessel occlusion device comprises a stent and a sheath. A drawstring may be actuated to gradually close a sheath orifice to control blood flow through the vessel.04-29-2010
20100331958HINGED ENDOVASCULAR DEVICE - A hinged endovascular device including a first stent portion having a first proximal end and a first distal end and a second stent portion having a second proximal end and a second distal end. A hinge assembly couples the first distal end and the second proximal end to each other. A method of inserting the device into a body lumen is also disclosed.12-30-2010
20130041453Vascular Shield and Delivery System - Devices for providing physical support to vascular regions including vascular regions that may contain an anastomosis region are disclosed. These devices may also deliver therapeutic agents to the vascular region. Methods for using these devices are disclosed, as well.02-14-2013
20120185034Coating For Implantable Devices And A Method Of Forming The Same - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can serve as a primer coating for subsequent coatings that can be used for the delivery of an active ingredient or a combination of active ingredients.07-19-2012
20100094404Methods of Making Biocomposite Medical Constructs and Related Constructs Including Artificial Tissues, Vessels and Patches - The disclosure describes methods of making collagen based biocomposite constructs and related devices. The methods include: (a) winding at least one collagen fiber a number of revolutions about a length of a support member having a long axis, the winding having at least one defined pitch and/or fiber angle relative to the long axis of the support member to form an elongate construct; and (b) applying a fluid polymeric material, such as, for example, an acrylate emulsion and/or other thermoplastic material, onto the collagen fiber during the winding step. Optionally, the fluid polymeric material can include antibiotics and/or other therapeutic agents for additional function/utility.04-15-2010
20090043375COMPOSITE EXPANDABLE DEVICE WITH IMPERVIOUS POLYMERIC COVERING AND BIOACTIVE COATING THEREON, DELIVERY APPARATUS AND METHOD - A composite expandable device for delivery into a vessel carrying blood comprising an expandable support frame having first and second end portions. An impervious polymer sleeve having inner and outer surfaces extending over the support frame. A coating is disposed on at least one of the inner and outer surfaces of the polymer sleeve for enhancing endothelial cell growth on the device and polymer sleeve.02-12-2009
20090043374Stent to be Placed in the Living Body - It is intended to proved a stent to be placed in the living body which shows a low restenosis rate after being placed in the body. A stent to be placed in the living body characterized in that the stent is in a long and thin almost tubular shape having both termini and provided with voids, the long and thin almost tubular body can be extended in the radial direction from the first diameter in the compressed state to be second diameter in the extended state, the strut section of the stent is in an almost square or rectangular shape, the whole surface of the stent has an outer surface, an inner surface and a side surface area corresponding to the area of the side surface is not more than 40% of the whole surface area corresponding to the area of the whole surface of the stent.02-12-2009
20090326637Stent - In a stent which joins a plurality of stent components by a strut, even when the repeated bending acts on the stent for a long period, the breaking of the strut can be prevented.12-31-2009
20090326636STENT - It is an object of the present invention to prevent a wire part including a stabilizer hook, a strut or the pulling-back member from separating from a connection part even when a force in a tensile direction is applied to a stent.12-31-2009
20090306765Bioerodible Endoprosthesis - An endoprosthesis can include a body including an underlying portion and a surface portion overlying the underlying portion. The underlying portion can include a bioerodible metal in the form of a matrix and corrosion enhancing deposits within the matrix. The surface portion including the bioerodible metal of the matrix. The surface portion having a first erosion rate when exposed to a physiological environment and the underlying portion having a second erosion rate when exposed to a physiological environment that is greater than the first erosion rate.12-10-2009
20130073028Co-BASED ALLOYS FOR BIOMEDICAL APPLICATIONS AND STENT - A first object of the present invention is to provide Co-based alloys for biomedical applications which are Ni-free, high intensity and high elastic modulus and are suitable for plastic workability. Moreover, a second object of the present invention is to provide Co-based alloys for biomedical applications having X-ray visibility. Furthermore, a third object of the present invention is to provide a stent using the alloys. The Co-based alloys for biomedical applications according to the present invention is configured by adding alloy elements having biocompatibility and an effect of increasing stacking fault energy of the alloys.03-21-2013
20110015720IMPLANTABLE ACCESS DEVICE AND METHOD FOR PREPARING THEREOF - The present invention concerns an implantable access device and a method for preparing the device. According to the invention the device comprises a shape memory base structure with a biological substructure suitable for cell adhesion, cell engraftment and proliferation for use in transferring and transporting fluid mixtures (blood, suspensions, drug formulations, emulsions, cell suspensions) in/into/out of a human or animal body.01-20-2011
20090299463Modified Surface For An Implantable Device And A Method Of Producing The Same - Implantable devices, such as stents, having a surface modified with TiN12-03-2009
20090270973STENT ASSEMBLY FOR THE TREATMENT OF VULNERABLE PLAQUE - An intravascular stent assembly for implantation in a body lumen, such as a coronary artery, is designed to treat a lesion with vulnerable plaque by reducing the fibrous cap stresses. A polymeric sleeve having first and second ends interconnects a first metallic stent and a second metallic stent. The first end is bonded to a distal end region of the first stent and the second end to a proximal end region of the second stent. The polymeric sleeve can be loaded with a therapeutic drug or agent to further control local thrombosis and/or induce healing if the plaque fibrous cap ruptures during or after implantation. Methods of making an intravascular stent assembly for the treatment of vulnerable plaque are also provided.10-29-2009
20090076588Endoprosthesis - In embodiments, a stent includes a stent body and a wire-form carrying a drug located along the stent body.03-19-2009
20090030501AXIALLY NESTED SLIDE AND LOCK EXPANDABLE DEVICE - The inventions relate generally to expandable medical implants for maintaining support of a body lumen and, in particular, to an axially nested, diametrically expandable, slide and lock vascular device for enlarging an occluded portion of a vessel. The axially nested vascular device desirably achieves both competitive crossing profiles while maintaining other key features, such as, for example, radial strength and luminal patency. The collapsed profile can also be made very thin without compromising radial strength. Thus, the vascular device can advantageously be deployed in small and difficult to reach areas or vessels. The axial nesting substantially eliminates radial overlap between mating structural elements thereby desirably allowing for a low, uniform profile.01-29-2009
20090030500Iron Ion Releasing Endoprostheses - An endoprosthesis that includes a base portion and a source of Fe(II) ions that is compositionally distinct from the base portion and releasable from the endoprosthesis under physiological conditions.01-29-2009
20130066415STENT - To provide a stent for enabling injuries to the wall of a lumen to be reduced, a stent 03-14-2013
20110022155Biodegradable Stent With Adjustable Degradation Rate - A biodegradable polymeric stent made from poly(L-lactide) and a low concentration of L-lactide monomer is disclosed. The concentration of L-lactide is adjusted to provide a degradation behavior that is suitable for different treatment applications including coronary, peripheral, and nasal.01-27-2011
20120116496STENT STRUCTURES FOR USE WITH VALVE REPLACEMENTS - The present embodiments provide a medical device for implantation in a patient comprising a stent and a valve. The stent comprises a proximal region comprising a cylindrical shape having a first outer diameter in an expanded state, and a distal region comprising a cylindrical shape having a second outer diameter in the expanded state. The second outer diameter is greater than the first outer diameter. A proximal region of the valve is at least partially positioned within the proximal region of the stent, and the distal region of the valve is at least partially positioned within one of tapered and distal regions of the stent. When implanted, the proximal region of the stent and the proximal region of the valve are aligned with a native valve, and the distal region of the valve is distally spaced-apart from the native valve.05-10-2012
20110046715Auxetic Fabric Structures and Related Fabrication Methods - Auxetic fabric structures, of the sort which can be useful in conjunction with composite materials, and related methods of fabrication.02-24-2011
20130166017Actively Controllable Stent, Stent Graft, Heart Valve and Method of Controlling Same - Sealable and repositionable implant devices are provided to increase the ability of endovascular grafts and valves to be precisely deployed or re-deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant. A surgical implant includes a self-expanding stent of a shape-memory material set to a given shape. The stent has a wall with a portion having a first thickness and a second portion having a thickness greater than the first. The second portion defines a key-hole shaped longitudinal drive orifice. The implant includes a selectively adjustable assembly having adjustable elements and being operable to force a configuration change in at least a portion of the self-expanding stent. The adjustable elements have a part rotatably disposed within the longitudinal drive orifice.06-27-2013
20090012598METHOD OF FABRICATING AN IMPLANTABLE MEDICAL DEVICE BY DEFORMATION OF A TUBE OR A SHEET - A method of fabricating an implantable medical device, such as a stent, from a plastically deformed tube or sheet is described herein. The implantable medical device may be an endoprosthesis such as a stent. The method may include elongating a tube longitudinally along a cylindrical axis of the tube. The method may further include forming a pattern that includes at least one strut on the elongated tube. A further embodiment may include stretching a sheet along an axis of stretching. The method may include forming a tube from the stretched sheet. The method may further include forming a pattern including at least one strut on the stretched sheet or the tube.01-08-2009
20100082091VASCULAR STENTING AND OTHER PROCEDURES - Described herein are flexible implantable occluding devices that can, for example, navigate the tortuous vessels of the neurovasculature. The occluding devices can also conform to the shape of the tortuous vessels of the vasculature. In some embodiments, the occluding devices can direct blood flow within a vessel away from an aneurysm or limit blood flow to the aneurysm. Some embodiments describe methods and apparatus for adjusting, along a length of the device, the porosity of the occluding device. In some embodiments, the occluding devices allows adequate blood flow to be provided to adjacent structures such that those structures, whether they are branch vessels or oxygen-demanding tissues, are not deprived of the necessary blood flow.04-01-2010
20100087912STENT WITH DUAL SUPPORT STRUCTURE - A intraluminal stent comprises a reticulated tube having an un-deployed diameter and expandable to an enlarged diameter. The tube includes a structural beam extending between first and second ends. The structural beam changes from a first geometry to a second geometry when the tube changes from the un-deployed diameter to the enlarged diameter. The structural beam includes first and second longitudinal elements each extending at least partially between the first and second ends and with a spacing between the first and second elements. Each of said first and second elements changes from the first geometry to the second geometry when the tube changes from the un-deployed diameter to the enlarged diameter for the spacing to remain substantially unchanged as the tube changes from the un-deployed diameter to the enlarged diameter.04-08-2010
20120271406Stent With Enhanced Friction - A stent for placement in a body lumen is fabricated by forming a tube having an un-deployed diameter sized for the tube to be placed on a deployment balloon and advanced through a body lumen to a deployment site. The tube is expandable upon inflation of the balloon to an enlarged diameter sized for the tube to be retained within the lumen at the site upon deflation and withdrawal of the balloon. The tube has a stent axis extending between first and second axial ends of the tube. The tube has an exterior surface and an interior surface. The tube is polished to polish the exterior surface to a smooth surface finish and with at least a portion of the interior surface having a rough surface finish rougher than the surface finish of the exterior surface.10-25-2012
20120271405Graft Devices and Methods of Use - A tubular graft device is provided comprising a tubular member and a fiber matrix of one or more polymers about a circumference of the tubular member. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a harvested saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft and connecting the graft between a first body space and a second body space, such as the aorta and a location on an occluded coronary artery, distal to the occlusion.10-25-2012
20120271401Mobile External Coupling for Branch Vessel Connection - An endovascular prosthesis includes a tubular body and a mobile external coupling. The tubular body includes a graft material and stents coupled thereto, and forms a lumen therethrough. The mobile external coupling includes a graft material, extends outwardly from the tubular body, and is generally frustoconically shaped. The mobile external coupling includes a base coupled to the tubular body, a top spaced from the tubular body, and a coupling lumen disposed between the base and the top that is in flow communication with the body lumen. An annular support wireform is coupled to the mobile external coupling, and is formed into a sinusoidal configuration having a plurality of opposing first crowns and second crowns, the first crowns of the support wireform extending around of the top of the mobile external coupling. The coupling graft material extending between the second crowns of the support wireform and the tubular body is unsupported.10-25-2012
20110106237ALTERNATING CIRCUMFERENTIAL BRIDGE STENT DESIGN AND METHODS FOR USE THEREOF - A stent includes a first section and a second section. The first section and the second section each include a plurality of expandable modules and a plurality of bridging modules. Each expandable module includes a plurality of strut elements that join together at a plurality of apices, and each bridging module includes bridging elements that connect an apex of a first module with an apex of a second module. In some aspects, the first section is more flexible along the longitudinal axis of the stent than the second section and is configured to be placed in a specific region of a vessel that requires flexibility to accommodate surrounding anatomy. In some aspects, the first section is more radially stiff than the second section and is configured to be placed in a specific region of the vessel that requires radial stiffness to counteract crushing force caused by surrounding anatomy.05-05-2011
20120150277CONTINUOUS DOUBLE LAYERED STENT FOR MIGRATION RESISTANCE - The present invention relates to stent structures having improved migration resistance. In particular, the invention relates to mesh stents, such as braided or twisted stent designs, where at least a portion of the stent is folded back over itself to form a multi-layered stent device. Such multi-layered portions provide for migration resistance, among other advantages.06-14-2012
20100324651Knitted Stent Jackets - Disclosed is an assembly for opening a vessel lumen comprising a radially expandable stent configured to open a vessel lumen, the radially expandable stent comprises a curved wall having a proximal portion, a distal portion and a lumen connecting the proximal portion and the distal portion. The assembly further comprises a knitted jacket comprising a plurality of interconnected loops, the knitted jacket further comprising a tubular wall that substantially surrounds an exterior surface of the radially expandable stent, and at least one retainer belt that slidingly passes through at least one knitted loop of the plurality of interconnected loops in the knitted jacket.12-23-2010
20090048659Medical devices having sol-gel derived ceramic regions with molded submicron surface features - According to one aspect of the present invention, implantable or insertable medical devices are provided, which contain sol-gel derived ceramic regions which have molded submicron surface features.02-19-2009
20110282431Endoprostheses - A medical device is provided with a porous region including a reservoir zone including a polymer and a protective zone between adjacent tissue and the reservoir zone that restricts the tissue from direct contact with the polymer.11-17-2011
20110282430Endoprosthesis - In embodiments, a stent includes a copolymer having a modulus of about 10 MPa or less and exhibiting hydrolytic degradation substantially by surface erosion.11-17-2011
20110282429PLASTIC STENT AND STENT OPERATION APPARATUS FOR THE SAME - Disclosed herein are a plastic stent and a stent operation apparatus for plastic stents. The plastic stent includes a stent body with a flow hole formed through the stent body in the longitudinal direction thereof. The stent operation apparatus includes a stent push rod having an externally threaded end. The stent body has an internal thread on the circumferential inner surface of the flow hole so that the internal thread engages with the externally threaded end of the stent push rod of the stent operation apparatus. The plastic stent is coupled to the stent push rod by the threaded engagement between the externally threaded end and the internal thread, is inserted into the body of a patient, is adjusted in location by pushing or pulling the stent push rod, and is released from the stent push rod at a correct location in the body of the patient by disengaging the threaded engagement.11-17-2011
20100268322Device For Treating A Duct Through Which Blood Flows And Associated Preparation Method - This device comprises a tubular endoprosthesis (10-21-2010
20100262223Stent Formed from Crosslinked Bioabsorbable Polymer and Methods of Making the Stent - A stent having a stent body made from a crosslinked bioabsorbable polymer is disclosed. A method of making the stent including exposing a tube formed from a bioabsorbable polymer to radiation to crosslink the bioabsorbable polymer and forming a stent body from the exposed tube is disclosed. The tube can include a crosslinking agent which induces crosslinking upon radiation exposure. Additionally or alternatively, the bioabsorbable polymer can be a copolymer that crosslinks upon exposure to radiation in the absence of a crosslinking agent.10-14-2010
20090276032Docking head for connecting vascular device to a vessel - A docking head of the present invention is provided to be mounted on a vascular graft having an outer diameter comparable with the inner diameter of the blood vessel so as to couple the vascular graft to a vessel wall in a suture-less manner. The docking head comprises a thin-walled hollow truncated cone having a passage sized to fit the outer diameter of the vascular graft wherein the cone is capable of connecting to the vascular graft while the hollow thin-walled truncated cone is provided with a plurality of outwardly pointing and inclined plurality of barbs. The docking head act as guiding, anchoring and sealing means between the vascular graft and the vessel.11-05-2009
20100324652Sealing Device and Delivery System - The invention relates to a sealing device for repair of cardiac and vascular defects or tissue opening such as a patent foramen ovale (PFO) or shunt in the heart, the vascular system, etc. and particularly provides an occluder device and trans-catheter occluder delivery system. The sealing device would have improved conformity to heart anatomy and be easily deployed, repositioned, and retrieved at the opening site.12-23-2010
20100057189MEDICAL DEVICES HAVING FLUORINE-CONTAINING POLYMER COATINGS WITH IMPROVED ADHESION - According to an aspect of the present invention, medical devices are provided which include a metallic substrate and a polymeric region disposed over and in contact with the metallic substrate. The polymeric region includes (a) a fluorine-containing polymer that contains at least one type of fluorine-containing monomer selected from a vinylidene fluoride monomer, a hexafluoropropylene monomer, and a combination thereof, and (b) an adhesion promoting copolymer that contains (i) at least one type of first monomer that covalently or non-covalently bonds with the metallic substrate and (ii) at least one type of second monomer selected from acrylate monomers, methacrylate monomers, fluorine-containing monomers, and combinations thereof.03-04-2010
20100049300Stent and Method and Device for Fabricating the Stent - Stent, as well as a method and device for fabricating the stent, wherein the stent has a tubular lattice structure comprising individual struts and at least one strut of which at least one longitudinal section runs with at least one directional component in the radial circumferential direction of the stent, wherein the surface of the longitudinal section facing the outside of the stent is curved only about the longitudinal axis of the stent. According to the invention, the surface of longitudinal section of the strut, which surface faces the inside of the stent, has such a curvature that the strut cross section is fluidically optimized.02-25-2010
20090043373VASCULAR IMPLANTS AND METHODS OF FABRICATING THE SAME - The present invention is directed to vascular implants and methods for fabricating the same. The implantable devices include but are not limited to stents, grafts and stent grafts. In many embodiments, the devices include one or more side branch lumens interconnected with the main lumen.02-12-2009
20110301690ENDOVASCULAR STAPLE - A plaque tack can be used for holding plaque against blood vessel walls such as in treating atherosclerotic occlusive disease. The plaque tack can be formed as a thin, annular band for holding loose plaque under a spring or other expansion force against a blood vessel wall. Focal elevating elements and/or other features, such as anchors, can be used to exert a holding force on a plaque position while minimizing the amount of material surface area in contact with the plaque or blood vessel wall and reducing the potential of friction with the endoluminal surface. This approach offers clinicians the ability to perform a minimally invasive post-angioplasty treatment and produce a stent-like result without using a stent.12-08-2011
20110301691METHOD OF MANUFACTURING TUBULAR STRUCTURE, AND STENT - A method of manufacturing a tubular structure is implemented by housing a tubular base, which has a side circumference surface formed in a bellows-like shape, in a polishing container, causing magnetic particles to flow along a circumferential direction of the tubular base due to action of magnetic poles, and supplying abrasive particles to the polishing container so that the abrasive particles flow along an axial direction of the tubular base, thereby polishing a surface of the tubular base. The method includes: a first polishing step of polishing an exposed surface of the tubular base by causing the magnetic particles and the abrasive particles to flow while an inner surface of the tubular base remains covered; and a second polishing step of polishing an exposed surface of the tubular base by causing the magnetic particles and the abrasive particles to flow while an outer surface of the tubular base remains covered.12-08-2011
20110288629REPOSITIONABLE ENDOLUMINAL SUPPORT STRUCTURE AND ITS APPLICATIONS - An endoluminal support structure includes strut members interconnected by pivot joints to form a series of linked scissor mechanisms. The structure can be remotely actuated to compress or expand its shape by adjusting the scissor joints within a range of motion. In particular, the support structure can be repositioned within the body lumen or retrieved from the lumen. The support structure can be employed to introduce and support a prosthetic valve within a body lumen.11-24-2011
20110288628COMPOSITE PROSTHESIS WITH EXTERNAL POLYMERIC SUPPORT STRUCTURE AND METHODS OF MANUFACTURING THE SAME - A prosthesis including a support structure for enhancing kink and/or crush resistance. The support structure is connected to an outer surface of the prosthesis and includes at least two components, one of which has a lower melting point than the other. The component with the lower melting point is used to connect the support structure to the outer surface of the prosthesis.11-24-2011
20080269870Method for Preparing Medical Stents - A method for preparing stents, with a stent blank subjected to a work process, in which the desired pattern is cut through the stent blank by evaporating the stent material with a diode-pumped fibre laser. The used fibre laser is preferably a picosecond laser having a minimum power of 20 W and a repetition frequency above 1 MHz.10-30-2008
20110295359Stent With Reduced Weld Profiles and a Closed-End Wire Configuration - A method for making an implantable stent includes the steps of (i) providing a plurality of elongate stent wires; (ii) forming said wires into a hollow tubular structure having opposed first and second open ends; (iii) terminating said wires at the second end; (iv) aligning the wires at the second end into a plurality of mated adjacent wires to define a plurality of abutting regions; (v) welding the mated adjacent wires to one and the other at the abutting regions to define a plurality of welds; and optionally (vi) chemically or electro-chemically removing a portion of the welds. The method may further include the steps of (a) extending at least one of the mated stent wires to provide an extended stent wire; (b) looping the extended stent wire so the extended end abuts a proximal pair of stent wires; and (c) welding the extended and looped wire to the proximal pair of wires. The step of looping may include the forming of the wire into a equilaterally arched loop having an apex, but not having other sharp bends.12-01-2011
20110295357Abdominal Aortic Stent - An abdominal aortic stent includes a first sub-stent and a second sub-stent, each having a front end and the circumference of the front end of each sub-stent is half of the circumference of the abdominal aorta, and when the circumference is gradually reduced to a rear end of each sub-stent, it has entered one side of the bilateral femoral arteries, wherein the rear ends of the sub-stents with full circumference of the cross-sectional area of the femoral artery are included therein; the first and second sub-stents are coated with external removable membrane to compress the sub-stents to generate smaller circumferences, and when the membrane has been removed, the sub-stents are fully extended to reconstruct the vascular flow path.12-01-2011
20080208312Stent Graft With Strips to Promote Localized Healing - An endoluminal stent graft includes segments of a healing promoter to promote the “healing in” of the distal and/or proximal neck(s) of the endoluminal stent graft in a vessel, thus reducing the risk of migration and the occurrence of endoleaks that can formed at the side of the neck(s) and the consequent feeding of the aneurysm sac. In some applications, the segments of the healing promoter are located within a proximal anchor region located near the proximal neck opening of the endoluminal stent graft and, optionally, within one or more distal anchor regions located near one or more distal neck openings of the endoluminal stent graft. In other applications, the segments of the healing promoter are located within the proximal anchor region, but not the distal anchor region.08-28-2008
20110295358ENDOLUMINAL PROSTHESIS - An endoluminal prosthesis (12-01-2011
20110295356STENT HAVING OPTIMIZED EXPANSION RATIO - An intravascular stent has an elongated tubular member that has a manufactured inner diameter and a manufactured outer diameter. The nominal expansion outer diameter (implanted diameter) is approximately 1.618 times larger than the manufactured outer diameter, which is referred to the Golden Ratio. The Golden Ratio provides for optimal crimping and expansion aesthetics, stent expansion uniformity, and uniform coatability for stent receiving a drug coating.12-01-2011
20100191319ATRAUMATIC STENT AND METHOD AND APPARATUS FOR MAKING THE SAME - A method of braiding a stent includes braiding a number of elongate filaments around a mandrel using tensioned braiding carriers without spooling the filaments to the tensioned braiding carriers to form a braided stent having atraumatic ends.07-29-2010
20090216311INTRALUMINAL SUPPORT FRAME - Intraluminal support frames for placement within a body vessel are provided. The support frames include a plurality of ring structures and first and second sets of connector segments. Connector segments of the first set join adjacent pairs of ring structures while connector segments of the second set join at least three ring structures. Medical devices are also provided that include a support frame and an additional component, such as a graft member or valve member08-27-2009
20090157167METHOD OF PROMOTING CELL PROLIFERATION AND INGROWTH BY INJURY TO THE NATIVE TISSUE - The present invention relates to methods of treating tissue of the human body, specially, methods of promoting cell proliferation and ingrowth around implantable medical devices. The methods include inserting an apparatus comprising asperities adapted to injure native tissue at a desired anchoring location, injuring the native tissue at the desired anchoring location with the apparatus to initiate an injury response in the native tissue to thereby promote cell proliferation and ingrowth; and implanting the medical device at the treatment location.06-18-2009
20090018641LARGE VESSEL STENTS - Large cell stents can be made having a plurality of cylindrical segments; and a plurality of connectors that join the segments to form a hollow tube, in which each segment comprises a series of support elements joined end to end at turning points in a zig-zag pattern to form a cylinder; a first segment is joined to a second segment by a plurality of connectors, each connector connecting a turning point of a first segment to a corresponding turning point of a second segment; and cells of the stent comprise two support elements in a first segment, one connector, two support elements in a second adjacent segment, and a second connector, all connected in series to form a continuous line. In some embodiments, each turning point in the first segment is longitudinally aligned with turning point in the second segment.01-15-2009
20100211160PROSTHESIS FOR PLACEMENT AT A LUMINAL OS - An embodiment of the invention provides a prosthesis delivery system comprising a delivery catheter having an expandable member and a prosthesis carried over the expandable member. The prosthesis includes a radially expandable scaffold section and at least two anchors extending axially from an end thereof; and means for capturing at least the anchors to prevent the anchors from divaricating from the expandable member as the catheter is advanced through a patient's vasculature.08-19-2010
20100211159CIRCUMFERENTIALLY NESTED EXPANDABLE DEVICE - Expandable medical implants for maintaining support of a body lumen are disclosed. These implants comprise a circumferentially nested, diametrically expandable, moveable vascular device for enlarging an occluded portion of a vessel. The device can be configured to allow for motion such as rotating, translating, and/or slide and lock. One advantage of the circumferentially nested stent is that it maintains the expanded size, without significant recoil.08-19-2010
20100211157PARTIALLY BIODEGRADABLE STENT - A partially biodegradable stent includes a main net body of hollow cylindrical shape formed of elastically deformable wires interlaced with each other, the net body extending in a longitudinal direction and terminating at open opposite ends, and an auxiliary net portion provided at one of the open opposite ends of the main net body, the auxiliary net portion formed of a biodegradable wire which can be degraded and removed by a bodily fluid. The auxiliary net portion is formed by interlacing the biodegradable wire into a cylindrical shape independently of the main net body or by interlacing the biodegradable wire with the elastically deformable wires at one of the open opposite ends of the main net body.08-19-2010
20100036479Stented Heart Valve Devices - A stent frame including an annular portion having first and second ends, a central longitudinal axis, and a wire portion with at least two extending posts and a generally sinusoidal series of peaks and valleys between each of the at least two extending posts; an atrial portion extending from the first end of the annular portion, wherein the atrial portion includes a plurality of flares that extend radially outward relative to the longitudinal axis of the annular portion; and a ventricular portion extending from the second end of the annular portion, wherein the ventricular portion includes at least one flare that extends radially outward relative to the longitudinal axis of the annular portion.02-11-2010
20090099643WOVEN INTRAVASCULAR DEVICES AND METHODS FOR MAKING THE SAME - Self-expandable, woven intravascular devices for use as stents (both straight and tapered), filters (both temporary and permanent) and occluders for insertion and implantation into a variety of anatomical structures. The devices may be formed from shape memory metals such as nitinol. The devices may also be formed from biodegradable materials. Delivery systems for the devices include two hollow tubes that operate coaxially. A device is secured to the tubes prior to the implantation and delivery of the device by securing one end of the device to the outside of the inner tube and by securing the other end of the device to the outside of the outer tube. The stents may be partially or completely covered by graft materials, but may also be bare. The devices may be formed from a single wire. The devices may be formed by either hand or machine weaving. The devices may be created by bending shape memory wires around tabs projecting from a template, and weaving the ends of the wires to create the body of the device such that the wires cross each other to form a plurality of angles, at least one of the angles being obtuse. The value of the obtuse angle may be increased by axially compressing the body.04-16-2009
20090248133Double-Walled Stent System - A double walled stent system particularly suited for treating abnormalities of the right ventricular outflow tract is disclosed having an exterior stent component and an interior stent component. The exterior stent component is secured to the interior stent component in a non-fixed, sliding relationship. The exterior stent component includes a plurality of longitudinally-extending connectors such as straight or sinusoidal bands. The interior stent component has a generally tubular cylindrical body and is centered within the exterior stent component. The stent system has a contracted delivery configuration and a radially expanded configuration for contacting the vessel wall. When deployed, the longitudinally-extending connectors of the exterior stent component come in contact with the vessel wall and fix the stent system to the treatment site. The interior stent component also radially expands but remains centered inside the exterior component and makes little to no contact with the vessel wall.10-01-2009
20100114292Vessel Extender - An anastomotic device includes a tube and anastomotic coupler rings having vessel openings attached to each end of the tube. In an embodiment, the diameters of the vessel openings are the same.05-06-2010
20100114295THERMOELASTIC AND SUPERELASTIC NI-TI-W ALLOY - A radiopaque nitinol stent for implantation in a body lumen is disclosed. The stent is made from a superelastic alloy such as nickel-titanium or nitinol, and includes a ternary element including tungsten. The added tungsten in specified amounts improve the radiopacity of the nitinol stent comparable to that of a stainless steel stent of the same strut pattern coated with a thin layer of gold. Furthermore, the nitinol stent has improved radiopacity yet retains its superelastic and shape memory behavior and further maintains a thin strut/wall thickness for high flexibility.05-06-2010
20100114294Stent Member - A rotationally-symmetric stent graft for deploying in a curved vessel has identical spaced stents along its length, with the stents being further apart in the region of the greatest curvature. The ends of the stents are parallel to each other and to the ends of the graft. The inter-stent spacing may vary along the entire length of the graft or only adjacent one end.05-06-2010
20100114293Multibranch Vessel Extender - An anastomotic device has a tube with three or more tube portions that are connected together. A first anastomotic coupler ring is attached to a first tube portion. A second anastomotic coupler ring is attached to a second tube portion. In an embodiment, a third anastomotic coupler ring is attached to a third tube portion.05-06-2010
20100268323Inflammation Accelerating Prosthesis - A prosthesis sleeve that is deployed within a patient's vessel at a damaged tissue area. The sleeve includes an inflammatory inducing section that releases materials near the damaged tissue to accelerate or enhance the immune response for a period of time sufficient to result in a smooth layer of repaired tissue.10-21-2010
20090149940BIOABSORBABLE STENT WITH RADIOPAQUE LAYER AND METHOD OF FABRICATION - Embodiments of a stent and methods of fabricating the same with a bioabsorbable radiopaque layer are disclosed.06-11-2009
20090149942ENDOPROSTHESIS HAVING A NON-FOULING SURFACE - An endoprosthesis, e.g., a stent, that includes a pro-healing surface and a temporary non-fouling material attached to the surface, and a method of making the same are disclosed.06-11-2009
20090149941Compressible tubular tissue supports - The invention provides a novel compressed tubular tissue supports (06-11-2009
20100280592DRAWSTRING FOR REMOVAL OF STENT - Disclosed herein is a drawstring for removal of a stent. The drawstring includes a circumferential string which is made of soft material and is formed in an end of the stent body in an annular shape. A hook loop is formed by tying opposite ends of the circumferential string to each other. The hook loop protrudes a relatively long distance from the stent body. A marking wire made of radiopaque material is wound around the hook loop. Therefore, when X-rays or endoscope are applied to a relative portion of a patient's body, the position of the hook loop can be easily detected. Furthermore, because the hook loop is made of flexible and soft material, even though it comes into contact with an internal organ of the patient's body, the organ is prevented from being damaged by the hook loop.11-04-2010
20100280591DRAWSTRING FOR REMOVAL OF STENT - Disclosed herein is a drawstring for removal of a stent. The drawstring includes an end string, a longitudinal string and a circumferential string. The end string is formed in an end of the stent body in an annular shape in such a way that the end string passes, in a zigzag manner, through mesh arranged in a circumferential direction of the stent body. A hook loop is formed by tying opposite ends of the end string to each other. The longitudinal string extends at a first end thereof from the end string in the longitudinal direction of the stent body. The circumferential string extends from a second end of the longitudinal string and is formed in an annular shape in such a way that the circumferential string passes, in a zigzag manner, through mesh arranged in the circumferential direction of the stent body.11-04-2010
20110172759AXIALLY NESTED SLIDE AND LOCK EXPANDABLE DEVICE - The invention relates generally to expandable medical implants for maintaining support of a body lumen and, in particular, to an axially nested, diametrically expandable, slide and lock vascular device for enlarging an occluded portion of a vessel. The axially nested vascular device desirably achieves both competitive crossing profiles while maintaining other key features, such as, for example, radial strength and luminal patency. The collapsed profile can also be made very thin without compromising radial strength. Thus, the vascular device can advantageously be deployed in small and difficult to reach areas or vessels. The axial nesting substantially eliminates radial overlap between mating structural elements thereby desirably allowing for a low, uniform profile.07-14-2011
20110172758Stents Formed From Polymer-Bioceramic Composite With Radiopaque Bioceramic Particles - Implantable medical devices fabricated at least in part of a polymer-bioceramic composite having bioceramic particles with radiopaque functional groups grafted to a surface of the bioceramic particles are disclosed. Implantable medical devices fabricated at least in part of a radiopaque material having bioceramic particles with polymer chains grafted onto a surface of the bioceramic particles, the radiopaque functional groups being chemically bonded to the grafted polymer chains, are disclosed.07-14-2011
20100268324STENTS FOR PROSTHETIC HEART VALVES AND METHODS OF MAKING SAME - A single piece stent construction having a plurality of commissure posts, each of which extends upwardly from a solid ring along a bend line and generally along a central longitudinal axis of the stent.10-21-2010
20120109282Energized Stents and Methods of Using the Same - The present disclosure relates to surgical systems including energized/energizable stents, and methods of using the same in the prevention of restenosis. A surgical system for treating a stenosis and/or a restenosis site s provided. The surgical system includes an electrosurgical generator; an energy transmitting conduit connectable to the electrosurgical generator; and a stent positionable in a body lumen at a site of a stenosis. The stent is fabricated from an electrically conductive material and adapted to electrically communicate with the electrosurgical generator, and the energy transmitting conduit delivers electrosurgical energy to the site of the stenosis.05-03-2012
20120109281Sheaths Used in Polymer Scaffold Delivery Systems - A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. A sheath is placed over the crimped scaffold after crimping to reduce recoil of the crimped polymer scaffold. The sheath is removed before the medical device is implanted within the body.05-03-2012
20100121429Stent Graft Having a Flexible, Articulable, and Axially Compressible Branch Graft - A stent graft and method for positioning and deploying the stent graft within a vessel system that includes a main vessel and a branch vessel emanating from the main vessel. The stent graft includes a tubular shaped main body formed from graft material, a branch opening (aperture) (ring) in the graft material of the main body whose position can be varied. A tubular shaped branch graft can extend from the main graft. A side wall of the main body may be configured as a series of connected annular corrugations or pleats, and coupled to the main body to define and provide variable positioning of its branch opening (aperture).05-13-2010
20110196475STENT FOR PLACEMENT IN LIVING BODY, AND STENT DELIVERY SYSTEM - A stent includes a plurality of first wave-shaped struts extending in the axial direction of the stent and arranged in the circumferential direction of the stent, a plurality of second wave-shaped struts each located between the first wave-shaped struts, and one or more connecting struts each interconnecting the first wave-shaped strut and the second wave-shaped strut which are adjacent to each other, with the one or more connecting struts extending in the axial direction over a predetermined length. The apexes of the second wave-shaped struts are shifted a predetermined distance in the axial direction of the stent relative to the apexes of the first wave-shaped struts which are located close to the apexes in the circumferential direction of the stent and which are curved in the same direction as the apexes.08-11-2011
20100324656Carbon Composite Materials and Methods of Manufacturing Same - A method for manufacturing a carbon composite is provided. The method includes providing a carbon-containing resin material to which an appropriate concentration of catalyst particles may be added. Thereafter, the catalyzed resin may be subject to a high temperature range, at which point carbon in the resin to begins to couple to the catalyst particles. Continual exposure to high temperature leads to additional attachment of carbon to existing carbon on the particles. Subsequently growth, within the resin material, of an array of carbon nanotubes occurs, as well as the formation of the composite material.12-23-2010
20100023112BIOCORRODIBLE IMPLANT WITH A COATING COMPRISING A HYDROGEL - The invention relates to an implant having a base body consisting completely or partially of a biocorrodible metallic material, the material being such that it decomposes in an aqueous environment to yield an alkaline product and the base body has a coating comprising or containing a hydrogel, characterized in that the hydrogel has a reduced swelling capacity at an elevated pH.01-28-2010
20100082092Implant Made of a Biodegradable Magnesium Alloy - An implant made in total or in parts of a biodegradable magnesium alloy consisting of Y: 2.0-6.0% by weight, Nd: 1.5-4.5% by weight, Gd: 0-4.0% by weight, Dy: 0-4.0% by weight. Er: 0-4.0% by weight, Zr: 0.1-1.0% by weight, Li:0-0.2% by weight, Al: 0-0.3% by weight, under the condition that a) a total content of Er, Gd and Dy is in the range of 0.5-4.0% by weight and b) a total content of Nd, Er, Gd and Dy is in the range of 2.0-5.5% by weight, the balance being magnesium and incidental impurities up to a total of 0.3% by weight.04-01-2010
20100094402MEDICAL DEVICE SUITABLE FOR LOCATION IN A BODY LUMEN04-15-2010
20090254173Extendible stent apparatus - An expandable stent includes a tubular structure with an outer surface positionable adjacent to a vessel wall and an inner surface facing a lumen of a body passageway. The tubular structure further includes a plurality of expansion struts, connector struts and cells. The tubular structure has a first diameter which permits intraluminal delivery of the tubular structure into the body passageway, and a second expanded and deformed diameter which is achieved upon the application of a radially, outwardly extending force. A plurality of cavities are formed in the outer surface of the stent.10-08-2009
20090048658Skewed nodal-fibril ePTFE structure - The ePTFE structure includes an ePTFE tubular structure having opposite ends and a longitudinal axis. The ePTFE tubular structure is formed from rotating the opposite ends relative to one another in a direction of rotation about the longitudinal axis. The ePTFE tubular structure has a node and fibril micro-structure in which substantially all of the fibrils are oriented in the direction of rotation.02-19-2009
20100087910MEDICAL IMPLANT - A endoprosthesis includes a body comprising a plurality of interconnected struts. The body includes a bioerodible metal. At least a first strut of the plurality of interconnected struts includes a stripe on the surface of the first strut. The stripe including a nitride of the bioerodible metal, a fluoride of the bioerodible metal, or a combination thereof. The stripe runs along the length of the first strut. The stripe is part of a continuous network of stripes on struts adjacent to the first strut.04-08-2010
20100087911IMPLANT WITH A BASE BODY OF A BIOCORRODIBLE MANGANESE ALLOY - The invention relates to an implant with a base body composed entirely or in parts of a biocorrodible manganese alloy.04-08-2010
20080249602Artificial Blood Vessel Stent - The present invention discloses an artificial blood vessel stent, which can minimize the diameter of a stent insertion device because the diameter (profile) thereof is uniform and small over the entire length upon being loaded, and accordingly can be easily placed in a branched portion of a blood vessel using a puncture method. The artificial blood vessel stent comprises: (I) an artificial blood vessel body 10-09-2008
20090088834STENT FORMED FROM BIOERODIBLE METAL-BIOCERAMIC COMPOSITE - Medical devices and methods of fabricating such medical devices, such as stents, formed at least in part from a metal matrix composite including bioceramic particles dispersed within an erodible metal are disclosed.04-02-2009
20090157165Degradable Endoprosthesis - An endoprosthesis includes a body that has a first bioerodible metal and a surface, and a capsule formed of a second bioerodible metal disposed on the surface. The capsule includes a porous peripheral region and a drug-containing core. A method of making such an endoprosthesis is also disclosed.06-18-2009
20080208318MULTIPLE INDEPENDENT NESTED STENT STRUCTURES AND METHODS FOR THEIR PREPARATION AND DEPLOYMENT - Blood vessels and other body lumens are stented using stent structures comprising a plurality of radially expansible rings where at least some of the rings comprise axially extending elements which interleave with axially extending elements on adjacent unconnected rings. The ring structures may be open cell structures or closed cell structures, and the axially extending elements will typically be formed as part of the open cell or closed cell structure.08-28-2008
20080208315Coronary stent having a surface of multi-layer immobilized structures - A stent for coronary vessels, having a surface of multilayer immobilized structures, includes a stent body and a number of polyelectrolyte complex (PEC) layers stacking and being immobilized on the surface of the stent body, in which the PEC layer is formed of a polymer layer and an anticoagulant layer. The coronary stent is capable of effectively improving the hemocompatibility longevity over conventional stent using surface encapsulation of an anticoagulant layer for hemocompatibility improvement. Furthermore, the coronary stent can be use as a drug-eluting coronary stent, thus allowing for the time-releasing of drugs, and further preventing the thickening of vascular smooth muscle cells for causing vascular thrombosis.08-28-2008
20110172756Apparatus For Medical Applications - The present invention relates to an apparatus for medical applications. The apparatus includes an oblong conductive element having a distal end. A resistance element is disposed in the vicinity of the distal end. The resistance element changes the resistance thereof as a function of a temperature and/or an electromagnetic field. To this end, the resistance element is designed to reduce a temperature rise of the distal end caused by energy absorption from, for example, an electromagnetic field.07-14-2011
20100100169Medical devices containing biobeneficial particles - A method of modifying a medical device such as a stent with nano-constructs is disclosed. The method comprises applying a first fluid to the stent; immersing the stent being wet from the first fluid into a second fluid having a suspension of nano-constructs; and removing the stent from the second fluid and allowing the first and second fluid to be removed such that the nano-constructs are carried by the stent for in vivo application of the constructs to a target location of a mammalian subject. The nano-constructs can be attached to the surface of the stent, can be attached to a surface of the coating of the stent, can be embedded into the stent, or can be embedded into the coating.04-22-2010
20090276033Clad Composite Stent - A body compatible stent is formed of multiple filaments arranged in at least two sets of oppositely directed helical windings interwoven with one another in a braided configuration. Each of the filaments is a composite including a central core and a case surrounding the core. In the more preferred version, the core is formed of a radiopaque and relatively ductile material, e.g. tantalum or platinum. The outer case is formed of a relatively resilient material, e.g. a cobalt/chromium based alloy. Favorable mechanical characteristics of the stent are determined by the case, while the core enables in vivo imaging of the stent. The composite filaments are formed by a drawn filled tubing process in which the core is inserted into a tubular case of a diameter substantially more than the intended final filament diameter. The composite filament is cold-worked in several steps to reduce its diameter, and annealed between successive cold working steps. After the final cold working step, the composite filament is formed into the desired shape and age hardened. Alternative composite filaments employ an intermediate barrier layer between the case and core, a biocompatible cover layer surrounding the case, and a radiopaque case surrounding a structural core.11-05-2009
20090043372ALTERNATIVE MICROMACHINED STRUCTURES - Medical devices and methods for making and using the same. An example medical device may include an elongate core member and a tubular member disposed about a portion of the core member. The tubular member may have a plurality of slots formed therein. The medical devices may be configured to have a preferential bending direction.02-12-2009
20090281613Endoprostheses - An endoprosthesis includes a body defining a flow passage therethrough. The body is capable of maintaining patency in a blood vessel and includes iron or an alloy thereof. The body has a nano-structured surface comprising iron oxide in which the individual nano-structures have a height to thickness aspect ratio of at least 5:1.11-12-2009
20090287295Method of Manufacturing a Polymeric Stent with a Hybrid Support Structure - Methods of manufacturing polymeric intraluminal stents and intraluminal stents are disclosed. The methods provide a method of manufacturing polymeric intraluminal stents having a structure with hybrid strut configuration containing at least one circumferential ring element in the structure in combination with 1 geometric strut columns.11-19-2009
20090287294Braid-Ball Embolic Devices - Embolic implants, delivery systems and methods of manufacture and delivery are disclosed. The devices can be used for aneurysm treatment and/or parent vessel occlusion. Implant designs offer low profile compressibility for delivery to neurovasculature, while maintaining other necessary features such as density for occlusion purposes and desirable radial strength characteristics.11-19-2009
20090018643Stents - The invention provides a composition comprising a stent and a polymer scaffold.01-15-2009
20110172760APPARATUS AND METHOD FOR TISSUE ADHESION - An array of a plurality of shape memory material microposts (07-14-2011
20100137972SINTERED MOULDED BODY - A sintered molded body consisting of a material that contains aluminum oxide with chromium doping, zirconium oxide with Y-stabilization and strontium aluminates with variable Cr-doping, which is particularly suitable for medical applications.06-03-2010
20100137973Layered Bifurcation Stent - An implantable medical device has an outer stent with a tubular body disposed about a longitudinal axis. The outer stent includes members defining openings which are in fluid communication with a flow path. At least one opening is larger than adjacent openings when the outer stent is in an expanded state, and is positioned between the ends of the outer stent. The at least one larger opening is a side branch opening having a perimeter. The device also has an inner stent with a tubular body disposed within the outer stent and about a longitudinal axis. The inner stent has a branch portion with deployable petals positioned adjacent to the side branch opening of the outer stent. The petals are biased against the perimeter of the side branch opening such that the petals are restrained from opening outward when the outer stent is in an unexpanded state.06-03-2010
20080275537Stents with High Radial Strength and Methods of Manufacturing Same - Polymeric stents having fracture toughness and resistance to recoil after deployment are disclosed along with methods of manufacturing such stents. Improvements to mechanical characteristics and other improvements may be achieved by having polymer chains within individual stent struts oriented in a direction that is closer to or in line with the axis of the individual stent struts. The desired orientation of polymer molecules may be achieved by one or any combination of extruding polymers into hollow tubes to induce axially oriented polymer chains, applying a tensile load to polymer tubes to induce axially oriented polymer chains, and radially expanding polymer tubes to induce circumferentially oriented polymer chains. Stent patterns include struts defining diamond shaped cells and/or W-shaped cells.11-06-2008
20110208290STENT FOR THE POSITIONING AND ANCHORING OF A VALVULAR PROSTHESIS IN AN IMPLANTATION SITE IN THE HEART OF A PATIENT - The present invention relates to a stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient. Specifically, the present invention relates to an expandable stent for an endoprosthesis used in the treatment of a narrowing of a cardiac valve and/or a cardiac valve insufficiency. So as to ensure that no longitudinal displacement of a valvular prosthesis fastened to a stent will occur relative the stent in the implanted state of the stent, even given the peristaltic motion of the heart, the stent according to the invention comprises at least one fastening portion via which the valvular prosthesis is connectable to the stent. The stent further comprises positioning arches and retaining arches, whereby at least one positioning arch is connected to at least one retaining arch.08-25-2011
20100137971Stent with a Structure of a Biocorrodible Material and a Controlled Corrosion Behavior - The invention relates to a stent with a structure of a biocorrodible magnesium alloy or tungsten alloy, which comprises a multiplicity of web sections connected to one another, wherein (i) the structure has a support structure of a number of first web sections connected to one another, which are designed to perform a function supporting the vascular wall or preserving the mechanical integrity of the stent after an expansion of the stent for a predetermined period of time and (ii) at least one second web section is present, which a) is directly connected to a selected first web section, b) does not perform a function supporting the vascular wall or preserving the mechanical integrity of the stent after the expansion of the stent for the predetermined period of time, and c) has a smaller average grain size than the first web sections of the support structure from (i).06-03-2010
20100057187INTRAVASCULAR STENT HAVING IMRPROVED DESIGN FOR LOADING AND DEPLOYING - A stent may be inserted into a vessel in order to open and then maintain the patency of the vessel. The stent has a strut design that increases the overall fatigue resistance of the stent. Each strut is tapered to better distribute strain and thus increase fatigue resistance. In addition, some of the struts may comprise protrusions to increase the pushability of the stent during loading into a delivery device.03-04-2010
20080249604APPARATUS AND METHOD FOR MEDICAL PROCEDURES WITHIN A SPINE - Devices and methods for performing a procedure within a spine are disclosed herein. In one embodiment, a method includes inserting an expandable member into an interior of a bone-related structure. The expandable member defines a first and second lumen. A medium is delivered through the first lumen and into the interior of the expandable member while within the interior of the bone-related structure. A filler material is delivered through the second lumen and into a cavity within the interior of the bone-related structure while the expandable member is disposed therein. An apparatus can include an expandable member that defines a first lumen in fluid communication with an interior volume of the expandable member, and a second lumen in fluid communication with an opening of the expandable member. The second lumen is configured to communicate a filler material through the opening and into an interior cavity of a bone-related structure.10-09-2008
20080249605Bioabsorbable Polymer, Non-Bioabsorbable Metal Composite Stents - Biocompatible materials may be configured into any number of implantable medical devices including intraluminal stents. The biocompatible material may comprise metallic and non-metallic materials in hybrid structures. In one such structure, a device may be fabricated with one or more elements having an inner metallic core that is not degradable with an outer shell formed from a polymeric material that is biodegradable. Additionally, therapeutic agents may be incorporated into the microstructure or the bulk material.10-09-2008
20110270382Drug Delivery After Biodegradation Of The Stent Scaffolding - Disclosed is a stent comprising a bioabsorbable polymeric scaffolding; and a plurality of depots in at least a portion of the scaffolding, wherein the plurality of depots comprise a bioabsorbable material, wherein the degradation rate of all or substantially all of the bioabsorbable polymer of the scaffolding is faster than the degradation rate of all or substantially all of the bioabsorbable material of the depots.11-03-2011
20110270378Mobile External Coupling with Internal Sealing Cuff for Branch Vessel Connection - An endovascular prosthesis includes a tubular body and a mobile external coupling. The tubular body includes a graft material and stents coupled thereto, a forms a lumen therethrough. The mobile external coupling extends outwardly from the tubular body. The mobile external coupling includes a graft material and is generally frustoconically shaped. The mobile external coupling includes a base coupled to the tubular body, a top spaced from the tubular body, and a coupling lumen disposed between the base and the top, wherein the coupling lumen is in flow communication with the body lumen. A cylindrical sealing cuff of graft material is attached to and extends from the top of the mobile external coupling towards the tubular body within the coupling lumen. The sealing cuff is configured to contact a portion of a branch vessel prosthesis and thereby provides an elongated interference seal between the branch vessel prosthesis and the mobile external coupling.11-03-2011
20110208289Flexible Stent-Grafts - A stent-graft includes a graft and annular stent springs, including first, second, and third tapered stent springs, coupled to a generally tubular portion of the graft. Each of the tapered springs include stent cells that circumferentially taper to a set of one or more circumferentially-adjacent narrowest stent cells within the spring. The first and second tapered springs axially adjacent; the second and third tapered stent springs are axially adjacent. The narrowest stent cell sets of the first and second springs are rotationally positioned on the portion of the graft with a non-zero relative angle shift therebetween, as are the narrowest stent cell sets of the second and third springs.08-25-2011
20080281401STAINLESS STEEL ALLOY HAVING LOWERED NICKEL-CHROMINUM TOXICITY AND IMPROVED BIOCOMPATIBILITY - The present invention is directed towards an austenitic, stainless steel series 300 alloy having improved biocompatible characteristics. The modified stainless steel alloy consists essentially of, in weight percent, about11-13-2008
20080288047Stent for Introducing Into Human Body Cavities, in Particular Into Blood Vessels - The invention relates to a stent (11-20-2008
20080294236Endoprosthesis with Select Ceramic and Polymer Coatings - An endoprosthesis, such as a stent, includes a ceramic, such as IROX, having a select morphology and composition and a polymer coating, both of which are deposited by pulsed laser deposition.11-27-2008
20080294237INFLATABLE DEVICES AND METHODS TO PROTECT ANEURYSMAL WALL - Methods and systems for preventing aneurysm rupture and reducing the risk of migration and endoleak are disclosed. Specifically, an inflatable liner is applied directly to treat the interior of the aneurysm site. Also disclosed are methods to deliver the inflatable liner directly to treatment sites.11-27-2008
20100036478Method Of Improving Fracture Toughness Of Implantable Medical Devices Through Annealing - Methods of fabricating a polymeric implantable device with improved fracture toughness through annealing are disclosed herein. A polymeric construct is annealed with no or substantially no crystal growth to increase nucleation density. After the annealing, crystallites are grown around the formed nuclei. An implantable medical device, such as a stent, can be fabricated from the polymer construct after the crystallite growth.02-11-2010
20090264982Stent with auxiliary treatment structure - A medical device for treatment of a stenosed body lumen, includes an open-ended cylindrical body carried on a distal end of a catheter for insertion of the device into the body lumen and placement at the stenosed site. The cylindrical body is movable between a collapsed position for insertion into the body lumen, and a radially expanded position pressed against the wall of the body lumen. In one embodiment the body sidewall is formed by a plurality of interconnected struts or elements defining openings therebetween, and at least one elongate ribbon is attached to an outer surface thereof for carrying a therapeutic agent. In another embodiment, the body is formed of interwoven elements defining a mesh-like structure, and the elements may comprise dissimilar materials, such as, e.g., copper and silver. In a further embodiment the body is formed of layers of different materials such as, e.g., copper, silver, and/or steel, laminated together. In a still further embodiment the device is designed for temporary placement of the catheter and body in a body lumen for treatment of a stenosed site, after which the catheter and body are withdrawn. In all forms the body may have an outwardly flared inlet end to reduce turbulence of fluid flowing through it, and/or a gel-like coating of a cholesterol-dissolving or blood clot dissolving agent may be placed on the device.10-22-2009
20080281402Stent Configurations - A stent may comprise a plurality of serpentine bands, wherein adjacent serpentine bands are connected by at least one connector strut. A serpentine band may comprise alternating straight struts and s-shaped struts. Connector struts may comprise first connector struts and second connector struts, wherein the first connector struts are nonparallel to the second connector struts.11-13-2008
20080269872STENT - A stent comprising an essentially tubular open supporting structure (10-30-2008
20080208314Prosthesis having a sleeve valve - Disclosed is a pressure sensitive prosthesis that includes a tubular member having a passageway extending therethrough and a sleeve attached about one end of the tubular member. The sleeve functions as a one-way valve to permit fluid flowing through the sleeve lumen in a first, distal direction and under a first pressure, while collapsing in response to fluid flowing in a second direction when the pressure thereof exceeds that of the first direction or pressure. One aspect of the invention includes a first opening and a second opening configured for allowing fluid flow from the passage to the lumen in the first direction.08-28-2008
20080243229Intracranial Stent and Method of Use - A stent and stent catheter for intra-cranial use.10-02-2008
20080275538TUBULAR CUTTING PROCESS AND SYSTEM - A system and method for processing a tubular member comprises a hollow tubular member, a laser and a media flow. The laser is constructed and arranged to transmit laser energy to the tubular member. The laser energy is transmitted to the tubular member through a fluid column according to a predetermined pattern. The media flow is injected into the lumen of the hollow tubular member.11-06-2008
20080269871Implantable device with miniature rotating portion and uses thereof - A miniature rotating portion, used within the human body. Optionally and preferably, the device may be used for one or more of active filtration and removal of emboli, plaques and occluding materials within the cardiovascular system and any other bodily passageway, promoting blood clots and occluding material lysis and disassembly.10-30-2008
20100137970METHOD OF ELECTROPLATING A CONVERSION ELECTRON EMITTING SOURCE ON IMPLANT - Methods for preparing an implant coated with a conversion electron emitting source (CEES) are disclosed. The typical method includes cleaning the surface of the implant; placing the implant in an activating solution comprising hydrochloric acid to activate the surface; reducing the surface by H06-03-2010
20100145432IMPLANT AND METHOD FOR PRODUCING THE SAME - The present invention describes a method for producing an implant, in particular an intraluminal endoprosthesis, wherein the base material of the body (06-10-2010
20120197385STENT - Provided is a stent wherein the water-swellable polymer fine particles applied thereto rarely peel off even when the stent is deformed or when the water-swellable polymer fine particles are swollen. A stent wherein a plurality of water-swellable polymer fine particles are chemically fixed on the stent surface in a dispersed state is provided.08-02-2012
20110270380Mobile External Coupling for Branch Vessel Connection - An endovascular prosthesis includes a tubular body and a mobile external coupling. The tubular body includes a graft material and stents coupled thereto which forms a lumen therethrough. The mobile external coupling extends outwardly from the tubular body. The mobile external coupling includes a graft material and is generally frustoconically shaped. The mobile external coupling includes a base coupled to the tubular body, a top spaced from the tubular body, and a coupling lumen disposed between the base and the top, wherein the coupling lumen is in flow communication with the body lumen. A coupling deployment device is coupled to the coupling graft material to provide an extension force to extend the mobile external coupling from a collapsed configuration against the tubular body to an extended position wherein the mobile external coupling extends from the tubular body.11-03-2011
20090132025COMPOSITE STENT WITH INNER AND OUTER STENT ELEMENTS AND METHOD OF USING THE SAME - A composite stent structure includes separate and distinct stent elements or members: an outer stent element and an inner stent element removably attached to the outer stent element. The outer element may be, for example, a bioabsorbable stent typically constructed of a relatively non-resilient material such that the outer bioabsorbable stent element may not be self-expanding and subject to migration within the lumen over time. In contrast, the inner element may be, for example, a removable SEMS used to urge and maintain the outer element in position in the body lumen. The temporary inner SEMS may retain the composite structure (including the underlying inner element) in position until such time as the outer element is appropriately incorporated into the surrounding tissue or some other criteria occurs such that the removal of the SEMS is indicated. The SEMS may then be detached from the outer element and removed from the body lumen.05-21-2009
20090138072Devices, systems, and methods for endovascular staple and/or prosthesis delivery and implantation - Devices, systems, and methods for implanting expandable prostheses in the body lumens rely on stapling or anchoring the prostheses with separately introduced fasteners. The prostheses may be self-expanding or balloon expandable, and may include a single lumen or more than one lumen. After initial placement, a stapling system is introduced within the expanded prosthesis to deploy a plurality of fasteners to at least one prosthesis end. The stapling system may apply a force to the prosthesis to modify the shape of the prosthesis to conform to the shape of the vessel wall. The stapling system can be deflected in one or more distinct steerable segments. A lumen extension or lumens may be coupled to the prosthesis to extend the reach of the prosthesis within the implantation site. Fasteners may also be applied to the lumen extensions.05-28-2009
20090292348VASCULAR STENTING AND OTHER PROCEDURES - Described herein are flexible implantable occluding devices that can, for example, navigate the tortuous vessels of the neurovasculature. The occluding devices can also conform to the shape of the tortuous vessels of the vasculature. In some embodiments, the occluding devices can direct blood flow within a vessel away from an aneurysm or limit blood flow to the aneurysm. Some embodiments describe methods and apparatus for adjusting, along a length of the device, the porosity of the occluding device. In some embodiments, the occluding devices allows adequate blood flow to be provided to adjacent structures such that those structures, whether they are branch vessels or oxygen-demanding tissues, are not deprived of the necessary blood flow.11-26-2009
20090118814ENDOPROSTHESIS COATING - A method includes: providing a tubular substrate in a chamber, the tubular substrate having a lumen, an a luminal surface and a luminal surface; providing a target in the lumen; depositing a first coating onto the abluminal surface and a second coating onto the luminal surface while keeping the tubular substrate in the chamber. An endoprosthesis, such as a stent, including a first coating on at least one portion of its abluminal surface and a second coating on at least one portion of its luminal surface is also disclosed.05-07-2009
20090138071Cardia Stent - The present invention relates to a medical stent, and in particular to a cardia stent for treatment on the narrow carida of the oesophagus. The cardia stent according to the present invention is woven by wires of shape memory NiTi alloy. There is a drum-shaped locating port at its upper end, and a trumpet-shaped locating port at its lower end. The upper drum-shaped locating port is connected with the lower trumpet-shaped locating port by a supporting net tube. The remaining portions other than the drum-shaped locating port are coated with a membrane of medical flexible material that can be implanted into a human body. The cardia stent comprises at least an anti-reflux valve. The anti-reflux valve is of a triple-petal structure protruding downward that is made from a membrane of medical flexible material that can be implanted into a human body. The cardia stent has the advantages of: difficult to shift, matching with carida anatomy, high anti-reflux ability, easy operation, resisting the corrosion of gastric juice, and it can be used in expansion treatment on the narrow carida caused by variable reasons.05-28-2009
20090005855ENDOSCOPE TREATMENT TOOL - A stent system 01-01-2009
20090005853Integration Of Markers Into Bar Arms - A stent having a body capable of visualization under X-ray fluoroscopic techniques. The stent body includes radiopaque strut members. The stent body can also have a radiopacity gradient along the length of the stent body.01-01-2009
20100004733Implants Including Fractal Structures - An endoprosthesis includes a member having a surface that includes a fractal structure.01-07-2010
20090005854Stent having circumferentially deformable struts - Disclosed is a method of treating a bodily lumen with a stent, the method comprising: disposing a stent within a bodily lumen, the stent comprising a plurality of deformable struts that are substantially circumferentially aligned and are configured to selectively deform in a circumferential direction in localized regions in the struts upon application of an outward radial force; and expanding the stent by applying the outward radial force, wherein the outward radial force causes selective deformation of the deformable struts in a localized region in the struts.01-01-2009
20080319527SHAPED MULTI-DUROMETER FILLER - Embodiments of the invention include an aneurysm filler, comprising a main body having a transport shape and three-dimensional shape which is manifest when the main body is deployed in an aneurysm.12-25-2008
20090259292Multiple Orifice Implantable Heart Valve and Methods of Implantation - A surgically implantable multiple orifice heart valve having a valve frame with at least two orifices, each of which can accommodate a tissue valve.10-15-2009
20080319528MODULAR ENDOPROSTHESIS WITH FLEXIBLE INTERCONNECTORS BETWEEN MODULES - A modular endoprosthesis is configured to have improved flexibility during and after deployment by having separate endoprosthetic modules that are interconnected by flexible interconnectors. The modular endoprosthesis includes a plurality of separate endoprosthetic modules positioned adjacently so that a first end of a first endoprosthetic module is adjacent to an end of a second endoprosthetic module and a second end of the first endoprosthetic module is adjacent to an end of a third endoprosthetic module. Additionally, the modular endoprosthesis includes a plurality of flexible interconnectors coupled to the plurality of separate endoprosthetic modules so as to interconnect the first end of the first endoprosthetic module with the end of the second endoprosthetic module with a first flexible interconnector, and interconnect the second end of the first endoprosthetic module with the end of the third endoprosthetic module with a second flexible interconnector.12-25-2008
20090326641HELICAL OSTIUM SUPPORT FOR TREATING VASCULAR BIFURCATIONS - A prosthesis is disclosed for placement across an ostium opening from a main body lumen to a branch body lumen. The prosthesis comprises a radially expansible support at one end, a circumferentially extending link at the other end and at least one spiral frond extending axially therebetween.12-31-2009
20090326640MEDICAL DEVICE FOR BODY CAVITY AND METHOD OF PRODUCING THE SAME - A medical device for body cavity which has a main stent body and a sheet-shaped member having an opening and covering at least a part of the main stent body as described above. It is desirable that, when the main stent body is dilated from the first diameter in the compressed state to the second diameter, the above-described sheet-shaped member spreads so as to cover at least a part of the main stent body without restricting the movement of the main stent body toward the circumferential direction while the shape of the opening of the above-described sheet-shaped member is retained even after the dilation of the main stent body. The above-described medical device for body cavity is applied to a delivery system which has a first catheter for transporting the medical device for body cavity into the body. In this delivery system, the above-described medical device for body cavity is located at the front end of the first catheter as described above so as to allow indwelling thereof.12-31-2009
20090326638MEDICAL DEVICES FOR DELIVERY OF THERAPEUTIC AGENT IN CONJUNCTION WITH GALVANIC CORROSION - According to an aspect of the present invention, at least one ionic therapeutic agent is delivered from an implantable or insertable medical device that comprises an ion-conductive polymeric region that is disposed on a metallic region. The metallic region is in electrical contact with a dissimilar metallic region, such that a galvanic current is generated by the dissimilar metals when the device is implanted or inserted into a patient. Delivery of the ionic therapeutic agent from the ion-conductive polymeric region may be, for example, either accelerated or retarded by the galvanic current. According to another aspect of the present invention, implantable or insertable medical devices are provided which comprise: (a) a first metallic region having a first corrosion potential, (b) a second metallic region in electrical contact with the first metallic region and having a second corrosion potential that is greater than the first corrosion potential, and (c) a solid ion-conductive polymeric region, comprising an ion conducting polymer and an ionic therapeutic agent, disposed on the first metallic region, the second metallic region, or both.12-31-2009
20100268321DRUG-RELEASING GRAFT - A method of incorporating drugs into an implantable medical device. In one variation, water insoluble drugs are used to form crystals within the porous structure of the device. Upon implantation, the drug crystals dissolve slowly and release the drug into the surrounding tissue. In one example, a water insoluble drug is crystallized within the pores of an ePTFE vascular graft.10-21-2010
20090326635Arterial Endoprosthesis - An arterial endoprosthesis, in particular for the aorta, having an outer face designed to press against the inner wall of an artery and including, on its outer face, projections distributed in such a manner as to reduce the speed of a flow of blood passing between the artery and the prosthesis.12-31-2009
20090326639MEDICAL DEVICES HAVING SUPERHYDROPHOBIC SURFACES - According to an aspect of the invention, medical devices are provided, which have at least two superhydrophobic surface regions which engage one another when the medical device is deployed in vivo.12-31-2009
20110224775Stent Geometry - A non-expandable stent and a method for implanting the stent are provided. The stent includes a generally tubular body having a lumen defined therethrough. The body includes a proximal portion having a curved portion configured for placement proximal to a sphincter. The body further includes a distal portion having retaining member extending outward from a proximal end of the distal portion. The retaining member is configured for placement distal to the sphincter and for engagement of the sphincter.09-15-2011
20080306582Implantable medical devices with elastomeric copolymer coatings - Implantable medical devices with elastomeric copolymer coatings are disclosed.12-11-2008
20080306581Streamlined Stents - A stent for implantation within the body of a patient is disclosed. The stent can be formed from one or more stent modules comprising a plurality of stent struts, one or more of which have an inner contour designed for streamlined fluid flow when the stent is implanted within an anatomical passageway of the patient.12-11-2008
20110224776DEVICES AND METHODS FOR TREATING VASCULAR MALFORMATIONS - A device for treating vascular malformations includes a primary coil and secondary windings. The primary coil provides resilience and structural integrity while the secondary windings fill interstitial spaces in the primary coil to isolate the vascular malformation. The device may have increased density along a central portion to isolate the malformation. In another aspect, the device may have a central opening through which embolic materials may be delivered.09-15-2011
20090024204EXPANDABLE SUPPORT DEVICE AND METHOD OF USE - A closable-tip fracture stent for tissue repair is disclosed. The device can be used to repair hard or soft tissue, such as bone or vertebral discs. A method of repairing tissue is also disclosed. The device comprises a flexible or semi-rigid wall, defining an interior cavity, and one or more closable tips to close the hollow cavity. A delivery tool is also provided for removably carrying the orthopedic device to the treatment site.01-22-2009
20090024203SURGICAL SITE ACCESS SYSTEM AND DEPLOYMENT DEVICE FOR SAME - An expandable surgical site access system and method for using the expandable surgical site access system to perform minimally invasive, percutaneous surgeries to access the spine or other bone structures, organs, or locations of the body is disclosed. In one embodiment, the surgical site access system includes an elongated, expandable stent that is particularly adapted to be deployed in a body during a surgical procedure to provide access to a surgical site within the body. The stent defines a working channel through the body from a point of entry to the surgical site.01-22-2009
20090054966ENDOVASCULAR DEVICE WITH MEMBRANE - An endovascular device (02-26-2009
20090054965Methods For Producing Embolic Devices - A vascular implant is provided. The implant can comprise a first material layer and at least one metallic material disposed on at least a portion of the first material layer in a predetermined pattern. The implant can further comprise at least one hydrophobic material disposed on at least a portion of the surface of at least one of the first material layer and the at least one metallic material.02-26-2009
20090082847SYSTEM AND METHOD OF SECURING STENT BARBS - A stent assembly comprising a stent body. At least one barb extends from the stent body and is configured such that a free end thereof is biased to extend radially outward from the stent body. A belt is releasably positioned about the stent body and aligned with the barb to constrain the barb to a position with the free end proximate to the stent body. A method of forming a stent assembly is also provided.03-26-2009
20110230955EXTERNAL STENT - An external vein support comprising an elongate axial body including an axis, said body is plastically deformable by at least one of stretching, bending, twisting, and any combination thereof, relative to said axis.09-22-2011
20110230953ELLIPTICAL ELEMENT FOR BLOOD PRESSURE REDUCTION - Apparatus is provided for treating hypertension of a subject. The apparatus includes an implantable element which has a non-circular shape and which is configured to reduce the hypertension by facilitating an assumption of a non-circular shape by a blood vessel in a vicinity of a baroreceptor of the subject, during diastole of the subject. Other embodiments are also described.09-22-2011
20090036970CONTROLLED FRACTURE CONNECTIONS FOR STENT - The invention provides for intra-luminal stents, especially stent having controlled fracture connection, as well as, methods of making and using the same. In one embodiment, a stent for implantation into a vessel has a plurality of annular segments collectively forming tubular shape, characterized by at least first and second adjacent annular segments each defined by a plurality of struts and at least one joint interconnecting respective struts of the first and second segments on a non-permanent basis.02-05-2009
20080262598Intravascular device with netting system - An intravascular device for keeping open a previously constricted site within a vessel and for minimizing tissue debris at such a site from closing off the vessel is provided. The device includes an expandable substantially tubular body having a distal end and a proximal end. The device also includes a flexible netting system that is circumferentially disposed about the body, and extends beyond at least one of the distal end or proximal end. The netting system can expand along with the body to minimize release of tissues debris at the site from closing the lumen of the vessel. The netting system can include a plurality of pores to permit communication between fluid flow within the vessel and the vessel wall, and at least one pharmacotherapeutic agent for the treatment or prevention of certain conditions. A method for placing the device at a site of interest is also provided.10-23-2008
20080262597Prosthesis Fixation Apparatus and Methods - Apparatus and methods for endoluminally advancing a tubular prosthesis and a plurality of fasteners to a site in a lumen in a human body and passing the fasteners from an inner surface of the prosthesis through the prosthesis and a wall of the lumen to secure the prosthesis to the wall. Embodiments include simultaneous deployment of fasteners using a graft alone or in conjunction with a stent graft. Another arrangement includes guide lines to guide the end of the fixation deployment device to a specific location of the wall of the prosthesis.10-23-2008
20110230954STENT DEVICE HAVING FOCAL ELEVATING ELEMENTS FOR MINIMAL SURFACE AREA CONTACT WITH LUMEN WALLS - An improved stent device has a body structure in tubular form sized to an organ lumen in which it is to be used and made of a wire mesh or cage structure of interwoven or interdigitated strut sections, and a plurality of focal elevating elements of relatively small point-like size or vector-like edge in an array over outer surfaces of the wire mesh or strut sections of the stent body structure. The focal elevating elements elevate the wire mesh or strut sections away from and minimize surface area contact with the organ lumen walls. They also reduce contact pressure in regions neighboring the focal elevating elements in order to minimize trauma due to contact or movement against the organ lumen walls. A preferred use for the stent device is in a blood vessel lumen, particularly to retain plaque dissection after balloon angioplasty.09-22-2011
20090118815STENT - Endoprosthesis includes coatings of selected porosity formed of particulates of ceramics, metals, drugs and/or polymers.05-07-2009
20090105806STENT - A tubular prosthesis can be formed by rolling a sheet of material about a longitudinal axis, thereby forming a plurality of annular rings that can be arranged so as to be longitudinally adjacent one another, thus forming a tubular prosthesis. Each annular member can expand and contract independent of the other annular members. A graft material can extend between the plurality of annular members.04-23-2009
20090105808Rapid Exchange Stent Delivery System and Associated Components - A rapid exchange stent delivery catheter includes an inner tubular member having a proximal portion, a distal portion, a stent holding portion located adjacent the distal portion of the inner member, and a guide wire lumen extending from a proximal guide wire opening disposed distal of the proximal portion of the inner member to a distal guide wire opening disposed at a distal end of the inner member. The proximal guide wire opening has a first length. An outer tubular member is slidably disposed about the inner member. The outer member has a proximal portion, a distal portion, and a guide wire opening disposed distal of the proximal portion of the outer member. The guide wire opening of the outer member has a second length that is shorter than the first length and a guide wire ramp extends into, and is movable along the first length.04-23-2009
20080275539Polymeric endoprosthesis and method of manufacture - Improved polymeric endoprostheses and methods of making endoprostheses are disclosed. Said endoprostheses exhibit improved overall compliance, selective regional compliance, and selective radial strength without varying the geometries of selected regions. Numerous other physical characteristics of said endoprostheses may be selectively varied during manufacture. Some embodiments may comprise one or more erodible material. Some embodiments may comprise one or more therapeutics incorporated into said endoprosthesis via a solvent in a supercritical state.11-06-2008
20090222079MEDICAL DEVICES HAVING ALLOY COMPOSITIONS - A medical device includes an alloy having chromium, niobium, and platinum, wherein the alloy forms at least a portion of the medical device.09-03-2009
20090264983Device, A Kit And A Method For Treatment Of Disorders In The Heart Rhythm Regulation System - A tissue lesion creating device is structured and arranged to be inserted through the vascular system into a body vessel adjacent the heart and to be subsequently subjected to a change of shape in order to penetrate into the heart tissue. The tissue lesion creating device may thus be used for treating disorders to the heart rhythm regulation system. A kit of devices provides a plurality of devices for creating a lesion pattern for treating such disorders.10-22-2009
20120197384IMPLANTABLE AND LUMEN-SUPPORTING STENTS AND RELATED METHODS OF MANUFACTURE AND USE - An implantable medical stent system, including a radially expandable stent including a filamental structure in a pattern surrounding a bore to form a substantially tubular wall along a length relative to a longitudinal axis; wherein the filamental structure includes at least one actuate crown with a crown peak having a radius of curvature located along a reference axis, and first and second arcuate crown shoulders on first and second sides, respectively, of the reference axis; and wherein the filamental structure also includes at least one pair of adjacent first and second elongated struts extending from the first and second crown shoulders, respectively.08-02-2012
20090240317Bioabsorbable Polymeric Medical Device - In embodiments there is described a cardiovascular tube-shaped lockable and expandable bioabsorbable scaffold having a low immunogenicity manufactured from a crystallizable bioabsorbable polymer composition or blend.09-24-2009
20090254172SELF CLEANING DEVICES, SYSTEMS AND METHODS OF USE - The invention relates to medical devices, systems and methods for preventing the embolic material flowing about a junction of at least one branch blood vessel and another blood vessel from entering the other blood vessel. The device includes a self cleaning flexible filter and a frame. The external surface of the filter is configured to temporarily trap at least some of the embolic material flowing about the junction as a result of the blood inflow though the filter. The filter is also configured to expel the trapped embolic material into the other blood vessel.10-08-2009
20090254171ENHANCED PROPERTY METAL POLYMER COMPOSITE - The invention relates to a metal polymer composite having properties that are enhanced or increased in the composite. Such properties include color, magnetism, thermal conductivity, electrical conductivity, density, improved malleability and ductility and thermoplastic or injection molding properties.10-08-2009
20100274346MULTI-SECTION FILAMENTARY ENDOLUMINAL STENT - A multi-section filamentary stent comprises a braided section, which is a cylindrical mesh of a first set of filaments, connected to at least one wound section comprising a second set of one or more filaments having a repeating configuration with a bent portion. The two sections are preferably connected by at least one continuous filament extending into both sections. The two sections may be connected by a weld, a suture, a common graft, an overlapping portion of the two sections, or one or more filaments of one section looping through portions of the other section. The stent may comprise a first section, having a braided first stent architecture with a first flexibility and a first radial force, and a second section, having a non-braided second stent architecture with a second flexibility less than the first flexibility and a second radial force greater than the first radial force, in which at least one continuous filament is integral to both the first and second sections. The stent may have a radially compressed configuration and a radially expanded configuration, in which the first section has a first shortening ratio, and the second section has a second shortening ratio less than the first shortening ratio. Such multi-section stents may comprise modular components of a modular stent, such as a bifurcated modular stent, adapted for joining together in situ. The multi-section stent may comprise a first section having a first percentage of open area and a second section having a second percentage of open area. The stent may also comprise a first section having a first stent architecture with an end effect wherein the radial strength at the end is less than elsewhere in the stent, and a second section having a second stent architecture to counteract the end effect. Methods for treating body lumen by implanting the stents as described herein are also disclosed, as is a method for counteracting a stent architecture end effect.10-28-2010
20100274347ENDOLUMINAL DEVICE FOR IN VIVO DELIVERY OF BIOACTIVE AGENTS - The present invention consists of an implantable structural element for in vivo delivery of bioactive active agents to a situs in a body. The implantable structural element may be configured as an implantable prosthesis, such as an endoluminal stent, cardiac valve, osteal implant or the like, which serves a dual function of being prosthetic and a carrier for a bioactive agent. Alternatively, the implantable structural element may simply be an implantable article that serves the single function of acting as a time-release carrier for the bioactive agent.10-28-2010
20090248134STENT WITH POLISHED EYELET - A stent for use in a stent graft comprising a strut region comprising at least two struts, the struts having at least one radius of curvature; a bend connecting the at least two struts and forming an eyelet region, where the strut region and the eyelet region are electropolished and the eyelet region is locally polished; and an eyelet positioned in the eyelet region, having at least one radius of curvature greater than zero is provided. A method of manufacturing the same also is provided.10-01-2009
20090248132Double-Walled Stent System - A double walled stent system particularly suited for treating abnormalities of the right ventricular outflow tract is disclosed having an exterior stent component and an interior stent component. The exterior stent component includes a plurality of longitudinally-extending connectors such as straight or sinusoidal bands. The interior stent component has a generally tubular cylindrical body and is centered within the exterior stent component. The stent system has a contracted delivery configuration and a radially expanded configuration for contacting the vessel wall. When deployed, the longitudinally-extending connectors of the exterior stent component come in contact with the vessel wall and fix the stent system to the treatment site. The interior stent component also radially expands but remains centered inside the exterior component and makes little to no contact with the vessel wall.10-01-2009
20100152835Tapered Stent and Flexible Prosthesis - The disclosure relates to a tapered stent and flexible prosthesis. The stent has a first longitudinal region and a second longitudinal region. The second region is substantially parallel to and spaced axially apart from the first region. A plurality of struts is disposed intermediate the first region and the second region and circumferentially connects the first region and the second region. The first region has a longitudinal length that is greater than the second region longitudinal length. The struts have varying longitudinal lengths that gradually decrease from the first region to the second region. The flexible prosthesis comprises at least two alternating tapered stents.06-17-2010
20100152834IMPLANT FOR INFLUENCING BLOOD FLOW - The invention relates to an implant for blood vessels, in particular to influence the flow of blood in the area of arteriovenous malformations, with said implant having a wall comprising individual filaments combined so as to form a circular braiding, said circular braiding being positioned in elongated form and with a reduced diameter in an insertion catheter and expanding at the placement site thus adapting to the vessel diameter and increasing its braiding density.06-17-2010
20100161032BIOLOGICALLY ENGINEERED STENT - Biologically engineered stents are provided, some having novel double-walled and hybrid composition constructions that are suitable for multi-drug delivery. Some embodiments of biologically engineered stents (BES) in accordance with the invention can deliver drugs in the form of gene therapy vectors to cells in the walls of stented vessels, thereby promoting local production of therapeutic factors that attract and enhance the formation of endothelium in the stented vessel. Other embodiments of BES include xenografts, allografts or isografts comprising sleeve-like natural matrices derived from vessels of animal and human subjects including postmortem human donors.06-24-2010
20090036971PTFE LAYERS AND METHODS OF MANUFACTURING - Single, continuous PTFE layers having lateral zones of varied characteristics are described. Some of the lateral zone embodiments may include PTFE material having little or no nodal and fibril microstructure. Methods of manufacturing PTFE layers allow for controllable permeability and porosity of the layers, in addition to other characteristics. The characteristics may vary from one lateral zone of a PTFE layer to a second lateral zone of a PTFE layer. In some embodiments, the PTFE layers may act as a barrier layer in an endovascular graft or other medical device.02-05-2009
20100262222BIOERODIBLE, IMPLANTABLE MEDICAL DEVICES INCORPORATING SUPERSATURATED MAGNESIUM ALLOYS - A bioerodible, implantable medical device that includes a supersaturated magnesium alloy. The magnesium alloy includes magnesium and at least one alloying element present in a concentration in excess of the equilibrium solid solubility concentration of the alloying element in hexagonal close-packed magnesium [at 25° C].10-14-2010
20090048660IMPLANT OF A BIOCORRODABLE MAGNESIUM ALLOY AND HAVING A COATING OF A BIOCORRODABLE POLYPHOSPHAZENE - An implant of a biocorrodable metallic material comprising a coating having a biocorrodable polyphosphazene.02-19-2009
20080215132IMPLANTABLE DEVICES HAVING TEXTURED SURFACES AND METHODS OF FORMING THE SAME - Textured coatings for implantable medical devices can be provided in metallic or polymer surface layers having surface texture factors down to nanometer and sub-nanometer levels. Implantable devices having such textured surfaces and methods of coating such devices comprises providing a substrate surface of an implantable device and forming a coating layer of the substrate surface by directing a mixture of atoms of a first type of material and a second type of material toward the substrate surface while simultaneously and collinearly bombarding the substrate surface with ions, wherein the first type of material is substantially resistant to a removal process and the second type of material is substantially susceptible to a removal process.09-04-2008
20100217378Stents With Profiles For Gripping A Balloon Catheter And Molds For Fabricating Stents - Embodiments of stents having profiles that improve gripping of the stent on a stent delivery system are provided. Additionally, embodiments of molds for fabricating the stents are provided. A radially expandable stent can comprise a proximal section tapering inward to a proximal end of the stent and a distal section tapering inward to a distal end of the stent. The tapered sections can be adapted to improve the attachment of the stent to the delivery system and to facilitate the delivery of the mounted device into and through a bodily lumen.08-26-2010
20100228335STENTS MODIFIED WITH MATERIAL COMPRISING AMNION TISSUE AND CORRESPONDING PROCESSES - A stent scaffold combined with amniotic tissue provides for a biocompatible stent that has improved biocompatibility and hemocompatibility. The amnion tissue can be variously modified or unmodified form of amnion tissue such as non-cryo amnion tissue, solubilized amnion tissue, amnion tissue fabric, chemically modified amnion tissue, amnion tissue treated with radiation, amnion tissue treated with heat, or a combination thereof. Materials such as polymer, placental tissue, pericardium tissue, small intestine submucosa can be used in combination with the amnion tissue. The amnion tissue can be attached to the inside, the outside, both inside and outside, or complete encapsulation of the stent scaffold. In some embodiments, at least part of the covering or lining comprises a plurality of layers of amnion tissue. The method of making the biocompatible stent and its delivery and deployment are also discussed.09-09-2010
20120172970PROGENITOR ENDOTHELIAL CELL CAPTURING WITH A DRUG ELUTING IMPLANTABLE MEDICAL DEVICE - A medical device for implantation into vessels or luminal structures within the body is provided, which stimulates positive blood vessel remodeling. The medical device, such as a stent and a synthetic graft, is provided with a coating with a pharmaceutical composition containing a controlled-release matrix and one or more pharmaceutical substances for direct delivery of drugs to surrounding tissues. The coating on the medical device further comprises one or more barrier layers, and a ligand such as a peptide, an antibody or a small molecule for capturing progenitor endothelial cells in the blood contacting surface of the device for restoring an endothelium at the site of injury. In particular, the drug-coated stents are for use, for example, in balloon angioplasty procedures for preventing or inhibiting restenosis.07-05-2012
20100161031MAGNESIUM-BASED ALLOY - The present invention relates to compositions and structure of deformable alloys on the basis of magnesium with an optimum combination of mechanical properties (strength, plasticity) and a resistance to corrosion, including in vivo. Alloys of the new group possess an excellent formability at room temperature, high corrosion stability in sodium chloride solution, excellent heat resistance and can be used in various technical applications, particularly in vivo as a structural material for stents.06-24-2010
20100234935Detachable And Retrievable Stent Assembly - A stent assembly comprises an expandable stent having a first stent backbone which extends from the proximal end of the stent to the distal end of the stent. The stent comprises a first stent back bone oriented in a direction which is substantially parallel to a longitudinal axis of the stent, and a plurality of interconnected first stent members and second stent members. Each of the first stent members is oriented in a substantially longitudinal direction in the unexpanded state and the expanded state. Each of the second stent members is oriented in a substantially longitudinal direction in the unexpanded state and oriented in a substantially circumferential direction in the expanded state. The first stent backbone has a greater column strength than that of the plurality of interconnected stent members.09-16-2010
20100217379IMPLANTABLE MEDICAL DEVICE COMPRISING A PRO-HEALING POLY(ESTER-AMIDE) - The present invention relates to implantable medical devices, in particular stents, comprising pro-healing poly(ester-amide)s.08-26-2010
20100217377CALCIUM PHOSPHATE COATED STENTS COMPRISING COBALT CHROMIUM ALLOY - Disclosed herein are medical devices, such as stents, coated with calcium phosphate and processes for making the same. The stent can comprise a cobalt chromium alloy that has been treated to improve surface adhesion to the calcium phosphate and/or improve surface finish properties. A pharmaceutically active agent can be present in the calcium phosphate coating.08-26-2010
20100228336MEDICAL DEVICES AND METHODS OF MAKING THE SAME - Medical devices, such as stents, and methods of making the devices are disclosed. In some embodiments, a medical device includes an alloy having tantalum, tungsten, zirconium and niobium. For example, the alloy can include from about 20% to about 40% by weight of tantalum, from about 0.5% to about 9% by weight of tungsten, and from about 0.5% to about 10% by weight of zirconium.09-09-2010
20100228334Medical Devices and Method for Making the Same - Medical devices, such as stents, and methods of the devices are described.09-09-2010
20100217376MEDICAL DEVICES - An implantable medical device such as a stent includes a molybdenum/rhenium alloy.08-26-2010
20100222866METAL ALLOY FOR MEDICAL DEVICES AND IMPLANTS - The present invention relates to a medical device or implant made at least in part of a high strength, low modulus metal alloy comprising Niobium, Tantalum, and at least one element selected from the group consisting of Zirconium, Tungsten, and Molybdenum. The medical devices according to the present invention provide superior characteristics with regard to bio-compatibility, radio-opacity and MRI compatibility.09-02-2010
20080281400MEDICAL IMPLANT, IN PARTICULAR STENT FOR USE IN BODILY LUMEN - A medical implant, in particular a stent for insertion in a bodily lumen, having a base structure (11-13-2008
20130218258Abdominal Aortic Stent - An abdominal aortic stent includes a first sub-stent and a second sub-stent, each having a front end and the circumference of the front end of each sub-stent is half of the circumference of the abdominal aorta, and when the circumference is gradually reduced to a rear end of each sub-stent, it has entered one side of the bilateral femoral arteries, wherein the rear ends of the sub-stents with full circumference of the cross-sectional area of the femoral artery are included therein; the first and second sub-stents are coated with external removable membrane to compress the sub-stents to generate smaller circumferences, and when the membrane has been removed, the sub-stents are fully extended to reconstruct the vascular flow path.08-22-2013
20110130823STENT HAVING FUNCTION ELEMENTS - An endoprosthesis, in particular an intraluminal endoprosthesis, including a tubular base body and at least one function element, the at least one function element also being tubular and being arranged on the base body in such a way that the at least one function element surrounds the base body at least partially and in at least partial areas, so that it is aligned concentrically with the base body.06-02-2011
20100198334IMPLANTABLE INTRALUMINAL DEVICE AND METHOD OF USING SAME IN TREATING ANEURYSMS - A method and apparatus for reducing blood flow to an aneurysm proximate to a bifurcation having a source blood vessel a first branch vessel and a second branch vessel, the method comprising: providing a first mesh-like tube of bio-compatible material, the first mesh-like tube exhibiting a porosity index pre-selected to skew blood flow about the bifurcation away from the aneurysm; inserting the first mesh-like tube into the source blood vessel and the first branch vessel; and securing the first mesh-like tube to at least one of the source blood vessel and the first branch vessel, whereby blood flowing from the source blood vessel flows without undue impedance to the first branch vessel and the second branch vessel while being skewed away from the aneurysm.08-05-2010
20100198331Bioabsorbable Stent That Modulates Plaque Geometric Morphology And Chemical Composition - Methods of treating a diseased blood vessel exhibiting stenosis with a bioabsorable stent are disclosed. The implanted stent supports the section of the vessel at an increased diameter for a period of time to allow the vessel to heal. The stent loses radial strength sufficient to support the section of the vessel in less than 6 months after implantation, loses mechanical integrity, and then erodes away from the section. The biodegradable stent results in changes in properties of plaque with time as the stent degrades. The time-dependent properties include the luminal area of the plaque and plaque geometric morphology parameters.08-05-2010
20100036477STENT EDGE PROTECTION AND METHODS - A catheter assembly and related methods directed to stent edge protection for an edge of a stent. One example stent edge protect member is positioned with a distal end portion of the stent edge protect member arranged proximal of and adjacent to a proximal end of the stent. The stent edge protect member defines an outer surface that transitions from an outer surface of the stent at the proximal end of the stent to an outer surface of the catheter branch on which the stent edge protect member is positioned. The stent edge protect member can be positioned on a single catheter branch or multiple catheter branches.02-11-2010
20090319025RESONATOR FOR MEDICAL DEVICE - A device resonator for medical device is provided. The resonator device includes a helical structure and a capacitor structure. The resonator device can be used in conjunction with a medical device, including a stent.12-24-2009
20080300670Fabricating a stent from a blow molded tube - Disclosed is a method for fabricating a stent, the method comprising: positioning a polymeric tube inside a mold, wherein a high thermally conductive element covers at least a portion of the outer surface of the mold, the high thermally conductive element having a thermal conductivity that is greater than that of the mold; heating at least a portion of the mold; radially expanding the tube against the mold; and fabricating a stent from the radially expanded tube.12-04-2008
20090112306STENT SEGMENTS AXIALLY CONNECTED BY THIN FILM - In accordance with the present invention, there is provided a stent for insertion into a vessel of a patient. The stent has a front and back open ends and a longitudinal axis extending therebetween. The stent has a plurality of adjacent hoops that are held in alignment with the longitudinal axis between the front and back open ends by a thin film tube. The hoops are attached to either the inner or outer surface of the thin film tube. The stent is compressed into a first smaller diameter for insertion into the vessel with a delivery tube and a second larger diameter for deployment into the vessel. The inventive stent can be retracted into the delivery tube if it is improperly deployed.04-30-2009
20090112307STENT HAVING A BASE BODY OF A BIOINERT METALLIC IMPLANT MATERIAL - A stent having a base body of a bioinert metallic implant material wherein the base body is covered with an SiC coating. An external surface of the base body has a plurality of cavities which are filled with an antiproliferative active ingredient, A luminal surface of the base body has a coating which contains or comprises attractors for endothelial cells.04-30-2009
20110060400VISIBLE ENDOPROSTHESIS - A crack-resistant endoprosthesis for delivery in a body lumen can be comprised of a multilayered material. The multilayered material can include at least two layers having a boundary layer therebetween. The boundary layer is configured to inhibit cracks from propagating from a first layer-to a second layer. The different layers can be comprised of the same materials or different materials. It can be preferred that the multilayered material have layers that are comprised of resiliently-flexible materials, shape memory materials, and/or radiopaque materials.03-10-2011
20110060398ENDOPROSTHESIS WITH FILAMENT REPOSITIONING OR RETRIEVAL MEMBER AND GUARD STRUCTURE - An endoprosthesis includes a stent structure having an elongate member longitudinal portions of which overlap to define the crossover structures. The stent structure may also include loop structures, which are contiguous with the crossover structures, through which a filament extends. A guard structure is secured to the stent structure and located adjacent to the crossover structures to obstruct displacement of the filament between the longitudinal portions of the elongate member of the crossover structures. A method for operating the endoprosthesis includes displacing the loop structures toward one another along the filament to displaced positions relative to the suture structure for reducing the respective profiles of the stent structure and patch structure.03-10-2011
20120143307STENT06-07-2012
20100305684BIODEGRADABLE STENT AND METHOD FOR MANUFACTURING THE SAME - A stent includes a magnesium layer, a ceramic layer formed over the magnesium layer, and a magnesium compound layer interposed between the magnesium layer and the ceramic layer. The initial corrosion of the stent can be delayed, and the stent has excellent biocompatibility and thus can reduce side effects during cell proliferation and differentiation.12-02-2010
20130144374Graft Apparatus - Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.06-06-2013
20110029062STENT USED IN BLOOD VESSEL - The present invention discloses a stent for a blood vessel. The stent for a blood vessel comprises (i) an artificial blood vessel A made of fabric; (ii) an upper cylindrical stent B made of wires having a body B02-03-2011
20100331960ENDOPROSTHESIS AND ENDOPROSTHESIS DELIVERY SYSTEM AND METHOD - An endoprosthesis includes a structure which is self-expandable from a reduced profile to an expanded profile. The structure has one or more longitudinal portions and a transverse central plane about which the one or more longitudinal portions are symmetric. A removable sheath retains the one or more longitudinal portions in the reduced profile. A release structure is coupled to the sheath for removal thereof from the one or more longitudinal portions to provide the self-expansion thereof to the expanded profile. A method for implanting the endoprosthesis into a body of a patient includes inserting the structure which is covered by the sheath into the body of the patient such that the structure has the reduced profile. The release structure is then actuated for removing the sheath from the one or more longitudinal portions to provide the self-expansion to the expanded profile.12-30-2010
20110009949Nanoparticle loaded electrospun implants or coatings for drug release - Medical devices, such as stents, including a fibrous layer including particles are disclosed. Methods of forming such medical devices using electrospinning are disclosed.01-13-2011
20110009948Fiber Reinforced Composite Stents - Polymeric composite stents reinforced with fibers for implantation into a bodily lumen are disclosed.01-13-2011
20110213456SIDE-CHAIN CRYSTALLIZABLE POLYMERS FOR MEDICAL APPLICATIONS - Side-chain crystallizable (SCC) polymers are useful in various medical applications. In certain applications, heavy atom containing side-chain crystallizable polymers (HACSCCP's) are particularly useful. An example of a HACSCCP is a polymer that comprises a main chain, a plurality of crystallizable side chains, and a plurality of heavy atoms attached to the polymer. In certain configurations, the heavy atoms are present in an amount that is effective to render the polymer radiopaque. A polymeric material that includes an HACSCCP may be fabricated into a medical device useful for at least partially occluding a body cavity. For example, such a medical device may be an embolotherapy product. A polymeric material that includes a SCC polymer may also be fabricated into other medical devices, such as stents.09-01-2011
20110245905ENDOPROSTHESIS - Among other things, a bio-erodible implantable endoprosthesis comprises a member that includes (a) a core having a surface, and (b) a bio-erodible metal on a least a portion of the surface of the core, wherein the bio-erodible metal erodes more slowly than the core and includes openings through which physiological fluids can access the core upon implantation.10-06-2011
20110046716STENT - An endovascular stent, including: a guide portion and a drive portion; a plurality of flexible support arms, each including two opposing ends that are coupled to said guide portion and said drive portion respectively, said arms being moveable relative to each other between an expanded position and a compressed position; and said stent including at least one barrier portion, such that when said arms are moved to said expanded position, said arms configure the barrier portion into a selectively permeable barrier through which one or more articles may be introduced into a space between said barrier and a wall of a lumen receiving said stent.02-24-2011
20130190856METHODS AND APPARATUS FOR STENTING COMPRISING ENHANCED EMBOLIC PROTECTION COUPLED WITH IMPROVED PROTECTIONS AGAINST RESTENOSIS AND THROMBUS FORMATION - Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Apparatus and methods are also provided for use at a vessel branching. The present invention further involves porous polymer membranes, suitable for use in medical implants, having controlled pore sizes, pore densities and mechanical properties. Methods of manufacturing such porous membranes are described in which a continuous fiber of polymer is extruded through a reciprocating extrusion head and deposited onto a substrate in a predetermined pattern. When cured, the polymeric material forms a stable, porous membrane suitable for a variety of applications, including reducing emboli release during and after stent delivery, and providing a source for release of bioactive substances to a vessel or organ and surrounding tissue.07-25-2013
20090062902Stent for positioning in a body conduit or method for producing this stent - By a contrast means contained in an inventive stent which has a greater permeability for x-radiation features than the body tissue surrounding the stent in a relevant body conduit, this stent can be clearly detected in its position on an x-ray image of the relevant body conduit while at the same time exhibiting good biological compatibility; a gas, especially one contained in cavities of the stent is provided as a contrast means. The inventive production method for this stent with the aid of a catheter embodied specially for the purpose enables the production of the stent from a malleable polymer mass in the relevant body conduit so that the stent is adapted especially precisely to the shape of the relevant body conduit.03-05-2009
20090062900Devices, systems and methods to detect endothelialization of implantable medical devices - An implantable medical device including a radially-expandable body and an attached detection device. The detection device includes a sensor positioned on a surface of the radially-expandable body and configured to detect endothelialization of the surface. The detection device also includes a transmitter and a receiver. Systems incorporating the implantable medical device and methods of using the device are also disclosed.03-05-2009
20090062901Vascular device with valve for approximating vessel wall - A vascular device comprising a body movable from a collapsed insertion position to an expanded position having a larger cross-sectional dimension. The body includes a plurality of struts. At least two elongated struts extend distally from the body. A plurality of vessel engaging members extend outwardly from the body for engaging the internal wall of a vessel. A valve is movable between a collapsed delivery position and an expanded placement position, wherein at least a portion of the valve extends distally from the body in the delivery and placement positions and the elongated struts engage a distal portion of the valve in the placement position of the valve to retain the valve.03-05-2009
20110245906Sealable Attachment of Endovascular Stent To Graft - An endovascular prosthesis of the present invention includes an expandable stent and a means for sealably attaching a tubular graft to the stent within the stent's lumen. The means of sealably attaching a graft includes membranes, foams, polymeric materials and combinations thereof. Additionally, the present invention includes methods of forming an endovascular prosthesis and methods of implanting an endovascular prosthesis within a vessel to provide sealable securement of a tubular graft within the stent's lumen.10-06-2011
20110245904Implantable Prosthesis With Depot Retention Feature - A prosthesis for intraluminal drug delivery can comprise a plurality of interconnected struts that form a tubular scaffold structure. The struts include through-holes with an inner surface configured to retain a bioabsorbable depot. The bioabsorbable depot includes a drug-polymer composition that hydrolytically degrades upon implantation. The inner surface of the through-hole can be an entirely smooth and continuous area that is concave or convex, with no geometric discontinuities. The inner surface of the through-hole can include any number of constricted and distended regions to form grooves of a size and shape carefully selected to engage a corresponding geometric feature of the bioabsorbable depot.10-06-2011
20110213454Porous Synthetic Vascular Grafts with Oriented Ingrowth Channels - A vascular prosthesis is constructed from a structure having interconnected, helically oriented channel-porosity to allow oriented ingrowth of connective tissue into a wall of the prosthesis. The prosthesis can have a small internal diameter of 6 mm or less. Several different methods can be used to produce the prosthesis, including a fiber winding and extraction technique, a melt extrusion technique, and a particle and fiber extraction technique using either a layered method or a continuous method. Furthermore, mechanical properties of prosthesis are matched with mechanical properties of the host vessel, thereby overcoming problems of compliance mismatch.09-01-2011
20090048661 Stent Configurations - Improved stent configurations exhibiting limited recoil, resistance to compression and improved longitudinal flexibility are disclosed. The stent comprised of a plurality of annular elements aligned to form a cylindrical stent body. The annular elements are comprised of a plurality of open, generally boomerang-shaped segments interconnected top-to-bottom around each of the annular elements. Adjacent annular elements are interconnected by interconnecting element.02-19-2009
20100131043Endoluminal Implants For Bioactive Material Delivery - Disclosed herein are endoluminal implants for bioactive material delivery. The disclosed endoluminal implants come in the general forms of patches and sleeves and can deliver bioactive materials independently of other implantable medical devices such as stents.05-27-2010
20100131042Stent to be placed in the living body - It is intended to provide a stent to be placed in the living body which exhibits excellent extension properties even in a flexion site of a lumen in the body and shows a low restenosis rate after being placed in the living body. A stent to be placed in the living body characterized in that, as one of the characteristics thereof, the stent is in a long and thin tubular shape having both termini, the long and thin tubular body can be extended in the radial direction from the first diameter in the compressed state to the second diameter in the extended state, the stent has a first terminal section, a second terminal section, a third central section, a fourth section located between the first terminal section and the third central section and a fifth section located between the second terminal section and the third central section, the rigidity of the fourth section is lower than the rigidity of the first terminal section and lower than the rigidity of the third central section, and the rigidity of the fifth section is lower than the rigidity of the second terminal section and lower than the rigidity of the third central section.05-27-2010
20100070019 EXTRA-VASCULAR WRAPPING FOR TREATING ANEURYSMATIC AORTA AND METHODS THEREOF - A new extra-vascular wrapping (EVW) is disclosed. The EVW comprises of a (i) wrapping adapted to at least partially encircle at least a segment of an aorta, especially an aneurysmatic aorta, and (ii) anchoring means located at the distal portion of the wrapping adapted to immobilize the wrapping to the aorto-iliac bifurcation via engagement of the aorto-iliac junction, wherein the bifurcation-anchored wrapping is applied external to the aorta and further wherein the wrapping is collapse-resistant in the proximal-to-distal direction of the aorta. The EVW is presented with its various embodiments, such as gusset-like structured EVW, Sustained drug delivery EVW, supported EVW and ringed EVW. Methods for treating aneurysmatic aorta in an open-surgery procedure by utilizing the EVWs and by applying step of positioning a macroporous medical textile externally adjacent to the aorta are also disclosed.03-18-2010
20100063580STENTS HAVING BIODEGRADABLE LAYERS - A method for preparing a laminate coronary stent comprising: providing a stent framework; and depositing a plurality of layers on said stent framework to form said laminate coronary stent; wherein at least one of said layers comprises a bioabsorbable polymer.03-11-2010
20100063581Endoprosthesis For Controlled Contraction And Expansion - An endoprosthesis that has a plurality of annular elements, each connected to an adjacent annular element at least one connection location. Each annular element includes an interconnected series of struts, selected strut members of which are each connected to adjacent strut members at a longitudinal apex. The selected strut members extend to a strut end portion at a location on the longitudinally opposite site of the annular element from the apex. At least one of the strut members includes a first end portion at a first end of the strut member, which is located at the strut end portion, an intermediate portion hingedly connected to the first end portion, and a second end portion hingedly connected to the intermediate portion and extending to the apex. The endoprosthesis has a delivery diameter when in a delivery condition and a deployed diameter when in a deployed condition. Some of the strut members can have a nesting feature that is configured for nestingly receiving another strut member when the endoprosthesis is in the delivery condition. A scaffolding body of the endoprosthesis can have an inner and outer component, each having a set of interconnected strut members. The interconnected strut members of one component overlap those of the other to define a cooperating cell pattern. Also, the body of the endoprosthesis can be configured to naturally tend to contract when the body is smaller than a predetermined diameter and naturally tend to expand when the body is larger than a predetermined diameter.03-11-2010
20100063578BIFURCATED MEDICAL DEVICE FOR TREATING A TARGET SITE AND ASSOCIATED METHOD - Embodiments of the present invention provide medical devices and methods for treating a target site within the body. For example, one embodiment provides a stent graft for treating a target site proximate to a bifurcated lumen, wherein the stent graft includes a first tubular structure having proximal and distal ends and a side wall extending therebetween. The first tubular structure includes an opening defined within the side wall and is configured to define a first portion having first and second ends and a second portion having first and second ends. The opening corresponds to the first ends of the first and second portions and the second ends of the first and second portions respectively correspond to the proximal and distal ends of the first tubular structure, and at least a portion of the first and second portions are configured to be positioned within respective branches of a bifurcated lumen.03-11-2010
20100063579STENT - The present invention discloses a stent that is designed to be easily removed from a lumen such as an esophagus, a blood vessel, or other organs of a human body without performing a surgical operation. The stent of the present invention includes an elastic body unit that is formed in a cylindrical shape and has an elastic force and a covering unit that is combined with or coated on the elastic body unit. The covering unit includes an extending portion that is separated from an end portion of the elastic body unit.03-11-2010
20090216310Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient - An expandable stent including a plurality of positioning arches configured to be positioned within a plurality of pockets of a native heart valve and positioned on a first side of a plurality of native heart valve leaflets, a plurality of retaining arches configured to be positioned on a second side of the plurality of native heart valve leaflets opposite the first side, and at least one radial arch substantially circumferentially aligned with at least one of the plurality of positioning arches.08-27-2009
20110178590METAL STENT FOR TREATING LESIONS IN BLOOD VESSELS, COMPRISING A PACKAGING - The system according to the present disclosure includes a metal stent (07-21-2011
20100057188ENDOPROSTHESES WITH POROUS REGIONS AND NON-POLYMERIC COATING - Endoprostheses include an endoprosthesis wall that includes a surface layer that includes a metallic material and that defines a plurality of pores. A therapeutic agent fills one or more pores of the surface layer and a non-polymeric coating, covers the therapeutic agent in the one or more pores. The endoprostheses can, for example, deliver a therapeutic agent, such as a drug, in a controlled manner over an extended period of time.03-04-2010
20100070020Implantable Medical Device - The invention provides an implantable medical device comprising a fibrous polymer body comprising a plurality of electrospun poly(urethane) fibers, a support filament wrapped around the body, an outer layer around the filament for adhering the filament to the body, the outer layer comprising a plurality of electrospun poly(urethane) fibers, and a polymer primer coating at least the fibers of the body. The polymer primer comprises poly(lactide) and is attached to a heparin residue through a linker03-18-2010
20110082536IMPLANTABLE PRODUCT WITH IMPROVED AQUEOUS INTERFACE CHARACTERISTICS AND METHOD FOR MAKING AND USING THE SAME - An implantable medical device including a porous membrane that is treated with a hydrophilic substance to obtain rapid optimum visualization using technology for viewing inside of a mammalian body. These technologies include ultrasound echocardiography and video imaging such as that used during laparoscopic procedures.04-07-2011
20110251669METALLIC IMPLANT WHICH IS DEGRADABLE IN VIVO - The invention relates to a medical implant made of a metallic material. After fulfilling its temporary support function, the implant is degraded by corrosion at a predetermined rate. Negative long-term effects are thus avoided.10-13-2011
20110082535BALLOON TYPE STENT SYSTEM FOR TREATMENT OF OBESITY - A balloon type stent system for treatment of obesity is disclosed. An injection expansion unit and a plurality of distribution expansion units extend in a longitudinal direction of a stent unit body formed by coupling two sheets of synthetic vinyl in the shape of a cylinder. The injection expansion unit has an expansion agent injection port, and the distribution expansion units each have a distribution injection port communicating with a distribution channel. Connection ends are partially cut in the longitudinal direction such that the expansion units are divided into an integrated expansion unit and a separated expansion unit. The injection expansion unit and the distribution expansion units constituting the separated expansion unit are bent outward to form a balloon type stent unit. A tube has a length corresponding to a lumen length of the duodenum, and the tube is connected to the stent unit body by a connection wire.04-07-2011
20110153000NON-DESTRUCTIVE TISSUE REPAIR AND REGENERATION - A surgical stent made of biocompatible material for implantation in human tissue to enable blood and nutrients to flow from an area of vascular tissue to an area of tissue with little or no vasculature.06-23-2011
20110152999SYSTEMS AND METHODS FOR MAKING AND USING PERCUTANEOUSLY-DELIVERED PUMPING SYSTEMS FOR PROVIDING HEMODYNAMIC SUPPORT - A percutaneous pumping system for providing hemodynamic support to a patient includes a pumping sleeve that defines a lumen extending along the length of the pumping sleeve. The pumping sleeve is configured and arranged for insertion into patient vasculature. At least one rotatable magnet is disposed in the pumping sleeve. The at least one first magnet is configured and arranged to be driven to rotate by a magnetic field generated external to the pumping sleeve. At least one impeller is coupled to the at least one magnet. Rotation of the at least one magnet causes a corresponding rotation of the at least one impeller. An anchoring arrangement is coupled to the pumping sleeve. The anchoring arrangement is configured and arranged to anchor the pumping sleeve at a target pumping location when the pumping sleeve is inserted into patient vasculature.06-23-2011
20110071615Methods for Forming an Orthogonal End on a Helical Stent - A method of manufacturing a stent includes forming a wave form having a plurality of struts and a plurality of crowns. Each crown connects two adjacent struts. The wave form has a center and two portions extending from opposite sides of the center. The method includes wrapping a first portion of the wave form about a longitudinal axis in a first direction at a first pitch angle, starting at the center of the wave form, to define at least one turn oriented at the first pitch angle, and wrapping a second portion of the wave form about the longitudinal axis in a second direction that is opposite the first direction at a second pitch angle, starting at the center of the wave form, to define at least one turn oriented at the second pitch angle. The first pitch angle is opposite the second pitch angle.03-24-2011
20090018639ENDOPROSTHESIS COATING - An endoprosthesis, such as a stent, includes anchoring regions formed of polymer that enhance adherence of a coating, e.g. a drug eluting polymer coating, to a stent surface, e.g. made of ceramic. The anchoring regions can be formed using stamping processes.01-15-2009
20120123521BIOABSORBABLE STENTS WITH REINFORCED FILAMENTS - According to an aspect of the present invention, a stent is provided, which contains at least one filament that has a longitudinal axis and comprises a bioabsorbable polymeric material. Polymer molecules within the bioabsorbable polymeric material are provided with a helical orientation which is aligned with respect to the longitudinal axis of the filament. The stent is at least partially bioabsorbed by a patient upon implantation or insertion of the stent into the patient.05-17-2012
20120123520BLOOD-FLOW TUBING - An artificial or modified natural blood flow tubing has a helical-flow inducer to induce helical flow in such a fashion as to eliminate or reduce turbulence. One inducer is a tubular stent of expansible mesh having a helical vane.05-17-2012
20120123519TUBULAR SILK COMPOSITIONS AND METHODS OF USE THEREOF - Described are tubular silk fibroin compositions and methods for their manufacture and use. Tubular compositions as described herein can be produced in a range of high burst strengths, can easily be made in a range of inner diameters, can be derivatized with functional moieties, and can be produced in a range of permeabilities suitable for particularized uses. In one aspect, the tubular compositions can be used in the repair or replacement of damaged or diseased blood vessels, including, but not limited to vessels smaller than about 6 mm.05-17-2012
20110251671STENT SUITABLE FOR DEPLOYMENT IN A BLOOD VESSEL - A stent suitable for deployment in a blood vessel to support at least part of an internal wall of the blood vessel includes a central section, a first intermediate section, a first end section, a second intermediate section and a section end section. The stent is movable between a delivery configuration and a deployment configuration.10-13-2011
20110251670EXPANDABLE STENT THAT COLLAPSES INTO A NON-CONVEX SHAPE AND EXPANDS INTO AN EXPANDED, CONVEX SHAPE - An expandable stent that can transform between a collapsed state and an expanded state is described. The stent includes a first cross-sectional shape and a second cross-sectional shape. The first cross-sectional shape is a non-convex shape when the stent is in the collapsed state. Alternatively, the second cross-sectional shape is a convex shape when the stent is in an expanded state. The stent can be formed of super elastic Nitinol, which allows it to be shape set in the desired shape. Due to its shape setting properties and the non-convex cross-section, the stent is capable of dramatically reducing its cross-sectional radial profile which is beneficial in a variety of procedures.10-13-2011
20110034991ENDOPROSTHESIS AND METHOD FOR PRODUCING SAME - An endoprosthesis, in particular, an intraluminal endoprosthesis, e.g., a stent, having a basic mesh and a functional element attached to a carrier structure, the functional element having a different material composition than the material of the basic mesh in at least a portion of its volume. The carrier structure is arranged on the basic mesh in the first essentially finger-shaped end and protrudes away from the mesh essentially like a projection. The functional element is arranged on an area of the carrier structure protruding away from the base body and at least partially surrounds the area of the carrier structure.02-10-2011
20110034990BIOCORRODIBLE IMPLANT WITH ACTIVE COATING - One embodiment of the invention concerns an implant with a basic body of biocorrodible, metallic implant material with an active coating and/or cavity filling.02-10-2011
20110257725Blood Inflating Prosthesis - A prosthesis comprises a tubular member that defines an inner lumen and has an inner surface and an outer surface, an outer member secured to the tubular member and covering at least a portion of the tubular member outer surface and forming an outer chamber therewith, and at least one valve in the tubular member to regulate or control fluid flow between the tubular member lumen and the chamber.10-20-2011
20100262224Stent Made From An Ultra High Molecular Weight Bioabsorbable Polymer With High Fatigue And Fracture Resistance - A stent made from an ultra high molecular weight bioabsorbable polymer is disclosed herein. The bioabsorbable polymer can have a Mw greater than 1 million g/mole or greater than 2 million g/mole. Methods of making the ultra high molecular weight polymer stent without degrading the molecular weight are further disclosed.10-14-2010
20110213455STENT GRAFT - A stent-graft including an inner stent having a wall structure including juxtaposed strut-patterns with interconnected struts and connectors connecting the strut-patterns is described. The wall structure of the inner stent has a predetermined length. An outer stent is coaxially arranged around the inner stent and has a wall structure including juxtaposed strut-patterns with interconnected struts and connectors connecting the strut-patterns. The wall structure of the outer stent has a predetermined length and a flexible stretchable material layer arranged between the inner stent and the outer stent. The wall structure of the inner stent has a design differing from the design of the wall structure of the outer stent and the length of the inner stent is equal to the length of the outer stent.09-01-2011
20100262225DEVICE AND METHOD FOR TACKING PLAQUE TO A BLOOD VESSEL WALL - A tack device for holding plaque against blood vessel walls in treating atherosclerotic occlusive disease is formed as a thin, annular band of durable, flexible material having a plurality of barbs or anchoring points on its outer annular periphery. The annular band has a length in the axial direction of the blood vessel walls that is about equal to or less than its diameter as installed in the blood vessel. In a preferred embodiment, the tack device is formed as a compressible metallic mesh band having outer barbs on outer sides of the mesh structure. Another embodiment may have a plurality of compressible mesh bands may be formed spaced apart coaxially from each other and connected by longitudinally extending bridge members. A preferred method is to perform angioplasty with a drug eluting balloon as a first step, and if there is any dissection to the blood vessel caused by the balloon angioplasty, one or more tack devices may be installed to tack down the dissected area of the blood vessel surface, in order to avoid the need to install a stent and thereby maintain a ‘stent-free’ environment.10-14-2010
20110251668Stent With Therapeutic Substance - A stent includes a wave form that includes a cable including a plurality of strands. The wave form has a plurality of struts and a plurality of crowns, with each crown connecting two adjacent struts. The wave form is wrapped around a longitudinal axis at a pitch to define a plurality of helical turns. The stent includes a filler located within the cable. The filler includes a therapeutic substance.10-13-2011
20110152998PROCEDURES FOR VASCULAR OCCLUSION - A method of reducing blood flow within an aneurysm includes: injecting a contrast agent into a blood vessel including an aneurysm; deploying an occlusion device across the aneurysm; producing an image of the aneurysm including the contrast agent; and withdrawing the delivery device from the vessel after observing that the aneurysm has been obstructed by a desired amount. The image may be two-dimensional or three-dimensional. Observing that the aneurysm has been obstructed may include determining a degree of obstruction, for example by comparing an area or volume of the contrast agent in a first image and a second image. The desired amount may be a certain degree of obstruction, identification of a shape indicative of stasis such as a flat surface, an approximate hemisphere, a mushroom, or a crescent. If the occlusion device does not achieve the desired amount, a second occluding device may be deployed.06-23-2011
20100004734STENT FABRICATION VIA TUBULAR CASTING PROCESSES - Tubular casting processes, such as dip-coating, may be used to form substrates from polymeric solutions which may be used to fabricate implantable devices such as stents. The polymeric substrates may have multiple layers which retain the inherent properties of their starting materials and which are sufficiently ductile to prevent brittle fracture. Parameters such as the number of times the mandrel is immersed, the duration of time of each immersion within the solution, as well as the delay time between each immersion or the drying or curing time between dips and withdrawal rates of the mandrel from the solution may each be controlled to result in the desired mechanical characteristics. Additional post-processing may also be utilized to further increase strength of the substrate or to alter its shape.01-07-2010
20120203326MEDICAL PRODUCT COMPRISING A CHITOSAN-COATED WALL AND A METHOD FOR MANUFACTURING A MEDICAL PRODUCT - A method for manufacturing a medical product comprising a hollow body (08-09-2012
20080243230STENT HAVING RADIALLY EXPANDABLE MAIN BODY - A stent made of a material having a low strength and having a main body circumscribing a cylindrical shape and radially expandable from a contracted starting position into a dilated support position, comprising a) a plurality of support segments disposed around the circumference and arrayed on one another in the axial direction each segment being formed by a strut meandering in its coarse structure in its contracted starting position and having alternately opposing meandering curves expandable into the support position made of flexible material; b) a plurality of axial connectors connecting between zenith points of at least a part of the meandering curves in the axial-parallel direction of the support segments; and c) at least one means for stabilizing the strut coarse structure in its contracted starting position against radial expansion and being automatically detachable upon a radial expansion of the stent.10-02-2008
20080243228Implantable medical devices fabricated from block copolymers - Implantable medical devices fabricated from block copolymers are disclosed.10-02-2008
20090105807Stent having a multiplicity of undulating longitudinals - A method for implanting a balloon expandable stent at a site within a passageway of a curved coronary article. The stent includes at least two longitudinally spaced apart circumferential rings. At least one longitudinally extending connector extends between adjacent rings. The connector has at least one turn back portion that can expand or contract in length while being passed through a curved passageway. The stent is disposed on a stent delivery catheter having an inflatable balloon. The stent delivery catheter and the stent is delivered through the passageway to the site of implementation with the connector member expanding or contracting in length to facilitate delivery and placement of the stent. The stent is expanded at the site of implantation by inflating the balloon to force the stent radially outward against the wall of the coronary artery.04-23-2009
20110160839Endoprosthesis - An endoprosthesis, e.g., a bioerodable stent, that is treated by plasma immersion ion implantation on the surface and optionally in the bulk. Releasable therapeutic agent, drug, or pharmaceutically active compound may be incorporated into the treated surface of the endoprosthesis to provide desired medical benefits.06-30-2011
20110257726SCAFFOLDS FOR ORGAN RECONSTRUCTION AND AUGMENTATION - Biocompatible synthetic or natural scaffolds are provided for the reconstruction, repair, augmentation or replacement of organs or tissue structures in a patient in need of such treatment. The scaffolds are shaped to conform to at least a part of the organ or tissue structure and may be seeded with one or more cell populations. Inserts, receptacles and ports are also provided for the attachment of tubular vessels to the neo-organ scaffolds. The seeded scaffolds are implanted into the patient at the site in need of treatment to form an organized organ or tissue structure. The scaffolds may be used to form organs or tissues, such as bladders, urethras, valves, and blood vessels.10-20-2011
20110257724Flexible Stent Device with Magnetic Connections - A stent includes a plurality of bands aligned generally along a common longitudinal axis. The plurality of bands includes at least a first band having a plurality of first crowns and a second band adjacent to the first band and having a plurality of second crowns. A magnetic connection joins at least one of the first crowns and at least one of the second crowns.10-20-2011
20100324653DEVICE FOR CONNECTING TWO BLOOD VESSELS - A device for connecting abutting ends (12-23-2010
20110054591IMPLANTABLE MEDICAL DEVICES - A medical device includes a balloon catheter having an expandable member, e.g., an inflatable balloon, at its distal end and a stent or other endoprosthesis. The stent is, for example, an apertured tubular member formed of a polymer and is assembled about the balloon. The stent has an initial diameter for delivery into the body and can be expanded to a larger diameter by inflating the balloon.03-03-2011
20110054590VASCULAR PROSTHESIS WITH STRESS RELIEF SLOTS - A vascular prosthesis comprises generally tubular body placeable in contracted and expanded states and has an axial length and a circumferential dimension in the expanded state. The body includes a series of circumferential elements having first lengths. First and second connectors have connector lengths and join alternating ends of adjacent circumferential elements. The first length plus the connector lengths joined thereto equal a total circumferential length. Each connector length is between 2.5% and 25% of the total circumferential length. Adjacent circumferential elements and connectors extending therefrom are separated by a stress relief slot having a relief slot length of more than 50% and less than 95% of the total circumferential length. The stress relief slots have narrow width portions over a majority of the relief slot lengths, the narrow width portions having lateral dimensions of no greater than about 3 mm.03-03-2011
20110054589STENT WITH VARIABLE CROSS SECTION BRAIDING FILAMENT AND METHOD FOR MAKING SAME - A braided stent comprises a filament having at least one circular zone and at least two non-circular zones. Embodiments of the braided stent have a proximal segment, a middle segment, and a distal segment, wherein a porosity of the middle segment is lower than, a respective porosity of the proximal and distal segments. In one embodiment, a radial pressure of the middle segment is separately controlled to be different from, e.g., less than, a radial pressure of the distal segment. In another embodiment, a stiffness of the middle segment is separately controlled to be different from, e.g., less than, a stiffness of the distal segment.03-03-2011
20100070018Tubular Metal Prosthesis and Method of Making It - For welding a polished component of one metal to a polished prosthesis of another metal, ramp surfaces are used, to compensate for loss of precise dimensions of the two components at the surfaces that face each other at the weld interface, during the respective polishing procedures for the two metals.03-18-2010
20110264194Endoluminal Implant With Locking and Centering Fixation System - An implant centering system includes a sensor connected to a hollow cylindrical anchor via at least two struts. The hollow cylindrical anchor is transformable between a radially compressed configuration for delivery and a radially expanded configuration for lodging against a vessel wall. The struts longitudinally relocate the sensor between a first position in which the sensor is longitudinally spaced apart from the radially compressed anchor, and a second position in which the sensor is at least partially within a lumen of the radially expanded anchor and radially centered within vessel. In one embodiment, the struts are heat-set into a curved configuration and an externally applied force longitudinally relocates the sensor until the struts lock over center into their heat-set configuration. In another embodiment, radial expansion of the anchor longitudinally relocates the sensor without an externally applied force.10-27-2011
20110112626BIORESORBABLE VASCULAR IMPLANT HAVING HOMOGENOUSLY DISTRIBUTED STRESSES UNDER A RADIAL LOAD - A bioresorbable vascular implant for implantation in a bodily lumen has a tubular framework and includes one or more annular support members. Each of the one or more annular support members includes a plurality of struts interconnected by a hinge region. Each of the plurality of struts also includes a mid-section. The vascular implant also includes at least one viscoelastic material that enables transition of the vascular implant between a collapsed configuration and an expanded configuration. Each of the plurality of struts and the hinge region defines a cross-section. The moment of inertia increases from the mid-section towards the hinge region to accommodate the transition and resist a radial load applied to the vascular implant in the expanded configuration.05-12-2011
20100292776Bioerodible Endoprosthesis - A stent includes a first tubular element formed of a first bioerodible metal composition and second tubular element formed of a second biodegradable metal composition. The first and second tubular elements are concentrically arranged; and the first and second bioerodible metal compositions are different.11-18-2010
20110118818ENCAPSULATED OR COATED STENT SYSTEMS - A stent system comprising zero or more inner stents inserted into an outer stent. The inner stents and outer stent are separated and/or encapsulated by a protein-based material of a protein matrix and/or a set biocoacervate, each comprising one or more biocompatible proteins and one or more biocompatible solvents. The protein-based material may also include one or more carbohydrates and one or more pharmacologically active agents.05-19-2011
20110125249Stent Graft and Introducer Assembly - A stent graft (05-26-2011
20110125250Stent and Method for Manufacturing the Same - A method of manufacturing a stent includes forming a first cylindrical mesh structure by bending a first member in a zigzag-shape having peaks and valleys and a plurality of turns wound around an outer circumference of a manufacturing frame and forming a second cylindrical mesh structure by bending a second member in a zigzag-shape having peaks and valleys and a plurality of turns wound around an outer circumference of a manufacturing frame, wherein a bending track the second member crosses a bending track of the first member.05-26-2011
20100211158SURFACE COATING PROCESSES AND USES OF SAME - The present application relates to processes for coating surfaces and provides a method of forming a coating on a surface. The method involves bombarding a surface with particles having sufficient energy to remove surface material. At the same time an aerosol is delivered to the surface. The cooperative action of the particles impinging on the surface and the presence of the aerosol contribute to the formation of a coating on the surface.08-19-2010
20100324655TREATMENT DEVICE FOR A BLOOD CIRCULATION VESSEL - The device includes at least a tubular endoprosthesis (12-23-2010
20100324654IMPLANT AND METHOD FOR MANUFACTURING SAME - The present invention relates to a method for manufacturing an implant, in particular an intraluminal endoprosthesis, with a body containing metallic material, preferably iron. The method includes the following steps to control degradation of the implant: (i) providing the body of the implant; and (ii) tribochemically treating at least part of the body surface by means of beam particles. An implant produced in this way is also described.12-23-2010
20100185273DEVICE AND METHOD FOR TREATMENT OF MITRAL INSUFFICIENCY - A device for treatment of mitral annulus dilatation comprises an elongate body having two states. In a first of these states the elongate body is insertable into the coronary sinus and has a shape adapting to the shape of the coronary sinus. When positioned in the coronary sinus, the elongate body is transferable to the second state assuming a reduced radius of curvature, whereby the radius of curvature of the coronary sinus and the radius of curvature as well as the circumference of the mitral annulus is reduced.07-22-2010
20100179640Radially Expandable System For Use In Body Tubes - A radially expandable system (07-15-2010
20100179641MULTI-LAYERED STENTS AND METHODS OF IMPLANTING - A method of percutaneously delivering a multi-layered stent assembly to a desired implantation location of a patient including the steps of radially compressing a multi-layered stent assembly to a compressed size for implantation in a patient, the multi-layered stent assembly including a first stent, a second stent coaxially positioned within at least a portion of a length of the first stent, and a valve, wherein the first stent comprises at least one different material property than the second stent. The method further includes delivering the multi-layered stent assembly to the desired implantation location of the patient using a delivery system and substantially simultaneously expanding the first stent and the second stent of the multi-layered stent assembly at the desired implantation location to a radially expanded size that is larger than the compressed size.07-15-2010
20090171441ENDOVASCULAR GRAFT WITH SEPARATELY POSITIONABLE AND REMOVABLE FRAME UNITS - A device for repairing a vessel body including a plurality distinct and independently positionable, expandable frame units disposed within a tubular graft. The independent frame units are capable of being positioned, repositioned, or removed to conform the tubular graft to the anatomy of the vessel body.07-02-2009
20090171443STENT GRAFT HAVING FLOATING YARNS - An implantable graft device is disclosed. The device comprises a graft body forming a lumen defining a longitudinal axis and comprising proximal and distal ends. The graft body comprises a woven fabric having warp yarns aligned in a first direction and weft yarns aligned in a second direction. The weft yarns are woven with the warp yarns. A portion of the warp yarns along the longitudinal axis of the graft body are not interwoven with the weft yarns, defining floating yarns having loops aligned in one of the first direction and the second direction. The device further comprises an expandable stent disposed circumferentially about the longitudinal axis and received through the loops of the floating yarns to attach the stent to the graft body.07-02-2009
20090171442Z-STENT WITH INCORPORATED BARBS - A stent constructed from at least two individual monolithic stent units is provided. The stent includes at least two individual stent units. Each individual stent unit has, as a monolithic structure, a first strut, a second strut, and a third strut. A first apex adjoins the first and second struts, and a second apex adjoining the second and third struts, where the second apex is disposed in a direction generally opposite the first apex. The monolithic stent unit includes an attachment mechanism at the end of at least the first strut. The first strut of each monolithic stent unit is joined at an attachment point to the third strut of an adjacent monolithic stent unit. The attachment mechanism is bent to form an angle relative to the attachment point. A method of manufacturing the same stent also is provided.07-02-2009
20090171440WOVEN FABRIC WITH CARBON NANOTUBE STRANDS - A woven fabric for an implantable medical device includes a plurality of carbon nanotube strands interwoven with a plurality of textile strands, where each carbon nanotube strand comprises a plurality of carbon nanotubes. An implantable medical device comprises a component and a fabric secured to the component, where the fabric includes a plurality of woven carbon nanotube strands, and each of the carbon nanotube strands comprises a plurality of carbon nanotubes.07-02-2009
20100121428VASCULAR PROSTHESIS - A vascular prosthesis comprising a hollow, tubular body (05-13-2010
20120310327NON-FORESHORTENING, AXIAL TENSION CONSTRAINABLE STENT - Methods and devices for a non-foreshortening, axial tension constrainable stent are illustrated such that a length of the stent in a collapsed state is about equal to the length of the stent in an expanded state which provides for better stent placement, easier repositioning and removal, and reduced stent migration.12-06-2012
20120150276MEDICAL DEVICES AND METHOD FOR MAKING THE SAME - Medical devices, such as stents, and methods of the devices are described.06-14-2012
20100161030Device and Method for Producing Same - The invention relates to a device, in particular for medical use as an endoprosthesis, preferably as an intraluminal endoprosthesis, having a base body (06-24-2010
20100198336MEDICAL DEVICES AND METHODS OF MAKING THE SAME - Medical devices, such as stents, and methods of the devices are described. In some embodiments, the invention features a method of making a medical device including providing a body having an electrically insulating first member defining an elongated lumen, and an electrically conducting second member on a first surface of the first member, removing a portion of the second member, and forming the body into the medical device, e.g., a stent.08-05-2010
20100082093Medical Devices - Expandable stents and methods of using expandable stent within a body are described.04-01-2010
20100191320STENT FOR THE POSITIONING AND ANCHORING OF A VALVULAR PROSTHESIS IN AN IMPLANTATION SITE IN THE HEART OF A PATIENT - The present invention relates to a stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient. Specifically, the present invention relates to an expandable stent for an endoprosthesis used in the treatment of a narrowing of a cardiac valve and/or a cardiac valve insufficiency. So as to ensure that no longitudinal displacement of a valvular prosthesis fastened to a stent will occur relative the stent in the implanted state of the stent, even given the peristaltic motion of the heart, the stent according to the invention comprises at least one fastening portion via which the valvular prosthesis is connectable to the stent. The stent further comprises positioning arches and retaining arches, whereby at least one positioning arch is connected to at least one retaining arch.07-29-2010
20090292349SUPPORTS - The invention provides a support adapted for location exteriorly of a blood vessel, the support being locatable around the blood vessel and shaped to be in morphological relationship with the blood vessel, wherein the support is formed from a settable material and wherein the support may be formed into a tube; and a method of morphometric analysis of a patient's blood vessel using an imaging scanner which method comprises: 11-26-2009
20090076589METAL ALLOY FOR A STENT - A stent that is at least partially formed of a novel metal alloy, which novel metal alloy improves the physical properties of the stent.03-19-2009
20110190871Crush Recoverable Polymer Scaffolds - A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold has a pattern including an asymmetric closed cell connecting links connecting the closed cells.08-04-2011
20110190869ENDOPROSTHESIS - An endoprosthesis, particularly an intraluminal endoprosthesis, having a basic structure that is preferably configured in the shape of a hollow cylinder, preferably configured as a basic lattice. In the expanded state, an inner volume enclosed by the basic structure can be changed by means of the elasticity of the basic structure, where the basic structure can assume a normal state and a state of significant compression, with regard to its compression behavior, for further improvement of the healing progression when using an endoprosthesis according to the invention, where in the state of significant compression, the elasticity of the basic structure is significantly reduced as compared with the elasticity in the normal state. The state of significant compression is characterized by the fact that an inside diameter threshold value of the basic structure is not reached, or that a compression pressure threshold value is exceeded. In this connection, the inside diameter threshold value preferably amounts to about 75% of a nominal inside diameter, or the compression pressure threshold value preferably amounts to about 0.2 bar.08-04-2011
20110190870Covered Stent for Vascular Closure - A stent assembly includes a stent, a covering on at least a portion of the stent, and a string encircling at least a portion of the covering. The string is releasably engaged to the covering or stent or both the covering and the stent. The string can be adhered to the stent, or the stent assembly, to the covering of the stent assembly, or both the covering and the stent. The string can be wrapped around the stent or covering in an interwoven loop or knit pattern. The covering can be made to overlap a perforation in a body lumen such as an artery or blood vessel and prevent bleeding.08-04-2011
20110218616Cancer Stent Treatment Device Using Nanotechnology - This application is for a device using aptamers, multiwalled carbon nanotubes (MWCNTs) filled with nanosized iron oxide particles immobilized magnetically on a stent by a magnet and then subsequently killing circulating tumor cells (CTCs) attached to the aptamers by heating the carbon nanotubes with near infrared (NIR) lasers and then release from the stent by removing the permanent magnet and subsequent excretion of the MWCNTs.09-08-2011
20100016950Streamlined Stents - A stent for implantation within the body of a patient is disclosed. The stent can be formed from one or more stent modules comprising a plurality of stent struts, one or more of which have an inner contour designed for streamlined fluid flow when the stent is implanted within an anatomical passageway of the patient.01-21-2010
20100016949ANNULAR MESH - An annular mesh expandable radially from a compact diameter to a radially-expanded deployed disposition in which the mesh is capable of sustaining a radially outwardly directed resistive force even when flexing its longitudinal axis out of a straight line, the mesh being composed of stenting struts, the stenting struts being arranged in a plurality of zig-zag strings around the circumference of the lumen, with occasional connector struts joining adjacent strings to create a closed circumference unit cell between two such connector struts and two adjacent connected strings there being a plurality of such unit cells arranged in sequence around the circumference between said two adjacent strings; and characterised in that there is a non-constant increment of strut length, serving to displace along the longitudinal axis each unit cell relative to the circumferentially next adjacent unit cell.01-21-2010
20090281614Sinus patches for replacing defective sinuses at the aortic root - Sinus patches for replacing defective sinuses at the aortic sinus include a flat, flexible, domed piece of wall material which, except for possibly having pleats, has a three-dimensional dome shape, which is determined by the wall material itself.11-12-2009
20110118820MAGNETIC MEDICAL APPARATUS, KITS, AND METHODS - Medical devices with surfaces on which viable biologic cells are magnetically attracted and retained are disclosed along with methods of magnetic coating. The medical devices can be located in a carrier liquid containing high concentrations of magnetic cells before or after implantation. The carrier liquid with magnetic cells may be contact with the medical device in vitro or in vivo. In either case, the carrier liquid may have a concentration of magnetic cells that is high enough to facilitate coating of the medical device within an acceptable period of time, e.g., several hours or less. Magnetization of medical devices before, during, and/or after implantation and apparatus for performing the same are disclosed. Degaussing of magnetic medical devices is also disclosed.05-19-2011
20110118819METHOD OF MANUFACTURING A POLYMERIC STENT WITH A HYBRID SUPPORT STRUCTURE - Methods of manufacturing polymeric intraluminal stents and intraluminal stents are disclosed. The methods provide a method of manufacturing polymeric intraluminal stents having a structure with hybrid strut configuration containing at least one circumferential ring element in the structure in combination with 1 geometric strut columns.05-19-2011
20100198330Bioabsorbable Stent And Treatment That Elicits Time-Varying Host-Material Response - Methods of treating a diseased blood vessel exhibiting stenosis with a bioabsorable stent are disclosed. The implanted stent supports the section of the vessel at an increased diameter for a period of time to allow the vessel to heal. The stent loses radial strength sufficient to support the section of the vessel in less than 6 months after implantation. Upon complete absorption of the stent, the section moves and functions in a manner that is the same, more similar to, or substantially as a normal blood vessel. In particular, the section can have an increased diameter allowing increased blood flow and vasomotion is partially or substantially completely restored in the section.08-05-2010
20100161029Emulsifiers for Multiple Emulsions - The present invention relates to a stable multiple water-in-oil-in-water emulsion comprising:06-24-2010
20090062899COMPOSITE STENT WITH POLYMERIC COVERING AND BIOACTIVE COATING - A composite expandable stent for delivery into a vessel carrying blood comprising an expandable support frame having first and second end portions. A porous imprevious polymer sleeve having inner and outer surfaces extending over the support frame. A coating is disposed on at least one of the inner and outer surfaces of the polymer sleeve for enhancing endothelial cell growth on the device and polymer sleeve. The stent can be cylindrical or tapered.03-05-2009
20090062903IMPLANTABLE MEDICAL DEVICES WITH FLUORINATED POLYMER COATINGS, AND METHODS OF COATING THEREOF - An implantable medical device including an expandable stent with an amorphous fluoropolymer coating, and methods of coating the stent. The amorphous fluoropolymer coating may be optically transparent and resistant to chemical corrosion.03-05-2009
20120041541IMPLANT AND METHOD FOR THE PRODUCTION THEREOF - An implant, in particular an intraluminal endoprosthesis, having an implant body (02-16-2012
20120041540STENT TO BE USED IN TUBULAR ORGAN IN VIVO - Provided is a stent to be inserted into an in vivo organ having a tubular structure that allows a degree of freedom in design and excellent mechanical flexibility. A cylinder-shaped stent is inserted to be placed and used in the inner cavity of an in vivo tubular organ, wherein: the wall of the stent has a planar mesh pattern filled with a plurality of closed cells being adjacent to each other and having congruent shapes; the closed cells have point-symmetric parallel hexagonal shapes; all closed cells circumferentially adjacent to each other are congruent and similar in shape; two closed cells adjacent to each other sharing different sides form a substantially V-shaped member; and the vertex of each folded part in the substantially V-shaped member points to the circumferential direction.02-16-2012
20090118813NANO-PATTERNED IMPLANT SURFACES - A bioerodible endoprosthesis erodes to a desirable geometry that can provide, e.g., improved mechanical properties or degradation characteristics.05-07-2009
20120150275STENTS AND METHODS OF MAKING STENTS - The present invention relates to a stent having a longitudinally-extending passage defined by a plurality of seamless strut elements with spacing between them. Each of these strut elements are in the form of lines defining the passage. The strut elements have a thickness in the range of 30 microns to 150 microns and are formed as at least one written layer. Also disclosed are methods of making the stent.06-14-2012
20090018642Methods to improve the stability of celluar adhesive proteins and peptides - The present disclosure provides surface-binding cell adhesion polypeptides including cell adhesion polypeptides attached to a surface-binding moiety having binding affinity for one or more materials present in a metallic and/or non-metallic inorganic surface. The surface-binding cell adhesion polypeptides are useful for forming a layer having improved adhesion to and stability on at least a portion of a surface of an implantable medical device, such as a stent.01-15-2009
20090082849ENDOPROSTHESIS COMPONENT - The invention relates to an endoprosthesis component which is formed from a ceramic material and in which the ceramic material is partially coated with a titanium alloy. An uncoated surface portion of the endoprosthesis component is designed to interact as slide surface with another endoprosthesis component. A coated surface portion of the endoprosthesis component is designed to establish a connection to a bone. According to the invention, the part of the ceramic material forming an interface to the coating has a roughness R03-26-2009
20110172757BASE MATERIAL FOR REVASCULARIZATION - The present invention aims to provide a material for revascularization which enables the regeneration of a blood vessel at an extremely high efficiency by being transplanted into a defect of the blood vessel.07-14-2011
20080208317Anchoring Device for Stent - Disclosed is a stent supporting device. The support device anchors a stent in a manner such that an anchoring stent is inserted into a branch blood vessel adjacent to an artery in which the stent is disposed, and the anchoring stent is connected to the stent. Accordingly, the support device is safe because it does not use subsidiary members such as screws, which can injure a blood vessel. Further, since the support device allows the stent to have a length corresponding to the size of a treatment site, that is, the stent does not need to be longer than the size of the treatment site, it is easy to install the stent.08-28-2008
20120046732PROCESS FOR MANUFACTURING MAGNESIUM ALLOY BASED PRODUCTS - A process for producing a magnesium based product, comprising the production of a feedstock out of a magnesium based alloy or a mixture of magnesium based alloys, a subsequent thermo-mechanical treatment of the feedstock, and an annealing step wherein the feedstock is produced by semi-solid processing. The invention further provides products, in particular implants and more particular stents made according to said process.02-23-2012
20120046731INTRALUMINAL SCAFFOLD WITH CONFORMING AXIAL STRUT - Devices and methods for treating veins and venous conditions, such as chronic cerebrospinal venous insufficiency, are provided. In one aspect, the disclosed subject matter provides an intraluminal scaffold having a generally tubular body with a lumen defined therethrough, the tubular body having a compressed condition for delivery and an expanded condition for implant within a vessel having a distended portion, at least a length of the tubular body configured to form an enlarged portion in the expanded condition to engage a wall of the distended portion of the vessel. Methods for fabricating and using the scaffold, methods for remodeling a vein, and methods of deploying a medical device in a vessel without negatively impacting the function of a valve of the vessel, are also provided.02-23-2012
20120046730METHODS OF TREATING A CONDITION OF A VESSEL IN A PATIENT - Devices and methods for treating veins and venous conditions, such as chronic cerebrospinal venous insufficiency, are provided. In one aspect, the disclosed subject matter provides an intraluminal scaffold having a generally tubular body with a lumen defined therethrough, the tubular body having a compressed condition for delivery and an expanded condition for implant within a vessel having a distended portion, at least a length of the tubular body configured to form an enlarged portion in the expanded condition to engage a wall of the distended portion of the vessel. Methods for fabricating and using the scaffold, methods for remodeling a vein, and methods of deploying a medical device in a vessel without negatively impacting the function of a valve of the vessel, are also provided.02-23-2012
20120046729INTRALUMINAL SCAFFOLD HAVING AN ENLARGED PORTION - Devices and methods for treating veins and venous conditions, such as chronic cerebrospinal venous insufficiency, are provided. In one aspect, the disclosed subject matter provides an intraluminal scaffold having a generally tubular body with a lumen defined therethrough, the tubular body having a compressed condition for delivery and an expanded condition for implant within a vessel having a distended portion, at least a length of the tubular body configured to form an enlarged portion in the expanded condition to engage a wall of the distended portion of the vessel. Methods for fabricating and using the scaffold, methods for remodeling a vein, and methods of deploying a medical device in a vessel without negatively impacting the function of a valve of the vessel, are also provided.02-23-2012
20120004718Platinum Enhanced Alloy and Intravascular or Implantable Medical Devices Manufactured Therefrom - A platinum enhanced radiopaque alloy particularly suitable for manufacture of implantable and/or intravascular medical devices. A stent is one preferred medical device which is a generally tubular structure that is expandable upon implantation in a vessel lumen to maintain flow therethrough. The stent is formed from the alloy which has improved radiopacity relative to present utilized stainless steel alloys. This alloy preferably contains from about 2 wt. % to about 50 wt. % platinum; from about 11 wt. % to about 18 wt. % chromium; about 5 wt. % to about 12 wt. % nickel and at least about 15 wt. % iron.01-05-2012
20110166640STENT HAVING LESS INVASIVE ENDS AND IMPROVED RADIAL FORCE - The present invention provides a stent having less invasive ends and improved radial force. In one embodiment, the stent comprises a series of proximal apices disposed at a proximal end of the stent, a series of distal apices disposed at a distal end of the stent, and at least one angled strut segment disposed between the proximal and distal apices of the stent. At least one apex of the stent may comprise multiple curved portions. In one example, the radius of curvature of one of the curved portions is significantly greater, for example, at least 10 times greater, than each of the other radii of curvature of the apex. The curved portion having the significantly greater radius of curvature may be configured to engage a vessel wall in a less invasive manner.07-07-2011
20110166639Stent - A stent shaped as a three-dimensional body which is formed by interlaced threads (07-07-2011
20110166638FLEXIBLE STRETCH STENT-GRAFT - A stent device includes a first graft member, a second graft member and a stent frame defining a central axis. The frame has an abluminal surface engaged with the first graft member and a luminal surface engaged with the second graft member such that the first graft member and the second graft member encapsulates the stent frame along the length of the central axis. The stent frame includes a configuration where the stent frame is disposed on a curvature such that the abluminal surface has a radius of curvature of approximately 20 millimeters about a center of the curvature and the luminal surface defines a substantially constant effective cross-sectional area at any portion generally transverse to the central axis of the stent frame disposed about the curvature.07-07-2011
20120016461Fluid Flow Controller - A fluid pathway is provided with a flow controller in at least a portion of its length wherein the flow controller comprises an active surface capable of influencing the fluid flow through the fluid pathway, the configuration of the active surface conforming to at least one logarithmic curve conforming to the Golden Section.01-19-2012
20120016460 MEDICAL DEVICE SUITABLE FOR LOCATION IN A BODY LUMEN - A medical device suitable for location in a body lumen is movable between a first loaded configuration and a second loaded configuration. The device has an unloaded configuration which is intermediate the first loaded configuration and the second loaded configuration. The device can be a stent for deployment in a blood vessel.01-19-2012
20120016459Stent - A stent including a plurality of loop stents connected by struts so that it bends uniformly as a whole.01-19-2012
20120016458ENDOPROSTHESIS HAVING IMPROVED STRAIN DISTRIBUTION - An endoprosthesis for delivery in a body lumen can be configured to inhibit structural fatigue, crack formation, and elastic recoil while providing improved crimping and expansion uniformity and radial strength. As such, the endoprosthesis can include at least one multi-stage crest element connecting adjacent bar arms. The multi-stage crest element and, optionally, the connection or transition between the multi-stage crest element and the bar arms can form a plurality of undulations or curves to improve the distribution of the strains experienced by the endoprosthesis. The improved strain distribution can improve the structural integrity and prevent failure of the endoprosthesis.01-19-2012
20130013054Endovascular Implant Having an Integral Graft Component and Method of Manufacture - A covered stent including an endovascular implant having a polymeric stent structure with an integrally formed membrane-like graft component, also referred to as a stent-graft, and methods of manufacturing the one-piece stent-graft by an injection molding process. A molding system for creating the polymeric stent structure is injected with a melt stream of moldable material that is forced between a parting line of the molding system to create a thin, flexible membrane-like structure within the open areas or interstitial spaces of the molded stent structure. The stent-graft so created is a one-piece, unified structure molded from a polymeric material in a single manufacturing step.01-10-2013
20120059452PERCUTANEOUS ENDOPROSTHESIS USING SUPRARENAL FIXATION AND BARBED ANCHORS - An endoprosthetic device for treating abdominal aortic aneurysms using suprarenal fixation. A stent ring is anchored in an area above the renal arties using self-flaring barbs that project during the nitinol expansion process. Sutures extend from the stent ring to an area below the renal arties to a bifurcated trunk portion comprising a nitinol fabric on a non-kinking frame. The bifurcated trunk is sealed proximal the iliac arteries and includes iliac leg holders having self-flaring retention struts for non-traumatic holding of iliac leg prosthetics. Suprarenal fixation and collapsible cells having retention projections and barbs that only flare during the nitinol expansion process assist in lowering the devices profile and sheathability for percutaneous delivery and may provide for recapturing the anchored device.03-08-2012
20120029613Bioerodible Endoprosthesis - An endoprosthesis includes a composite. The composite includes a matrix comprising a bioerodible iron or a bioerodible iron alloy and particles within the matrix. The particles include palladium, manganese oxide, a transition metal oxide, or a combination thereof.02-02-2012
20110093061STENT HAVING RADIALLY EXPANDABLE MAIN BODY - A stent made of a material having a low strength and having a main body circumscribing a cylindrical shape and radially expandable from a contracted starting position into a dilated support position, comprising a) a plurality of support segments disposed around the circumference and arrayed on one another in the axial direction each segment being formed by a strut meandering in its coarse structure in its contracted starting position and having alternately opposing meandering curves expandable into the support position made of flexible material; b) a plurality of axial connectors connecting between zenith points of at least a part of the meandering curves in the axial-parallel direction of the support segments; (c) a plurality of x-ray marker projections, and d) at least one stabilizer for stabilizing the strut coarse structure in its contracted starting position against radial expansion and being automatically detachable upon radial expansion.04-21-2011
20110093060 Surgical Implant Devices and Methods for their Manufacture and Use - This disclosure is directed toward sealable and repositionable implant devices that are provided with one or more improvements that increase the ability of implants such as endovascular grafts to be precisely deployed or re-deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and/or with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant.04-21-2011
20110093059HYBRID STENT WITH HELICAL CONNECTORS - The present invention is a hybrid stent design using half-slot circumferential sets of strut members with short (<1.5 mm) slot length that has minimal fish scaling and excellent stent retention and flexibility. These half-slot circumferential sets of strut members are connected one to the other with helical connectors similar to those of the Palmaz stent. One important difference in the design of the stent of the present invention is that the helical connectors are attached to every other crown (rather than connected to every crown) to further improve stent flexibility. By appropriately varying the strut width of both the connected and unconnected curved crowns to be greater at the center than at their ends, an increased radial strength can be provided for a given maximum strain that is imparted to the stent when it is expanded to its maximum diameter.04-21-2011
20110093058GRAFT INCLUDING EXPANDABLE MATERIALS - A graft for facilitating treatment of a deformity in a blood vessel wall includes a tubular body defining a first end and an opposing second end. At least a portion of the tubular body includes a super-absorbent material integrated into the tubular body and configured to expand upon exposure to moisture.04-21-2011
20120059451Method of Manufacturing a Polymeric Stent Having Reduced Recoil - Methods of manufacturing polymeric intraluminal stents, and stents made by such methods, are disclosed. The methods provide for manufacturing polymeric intraluminal stents by inducing molecular orientation in the stents by radial compression thereby providing stents with low recoil post-deployment.03-08-2012
20120065722Bioabsorbable Superficial Femoral Stent Patterns With Designed To Break Links - Bioabsorbable polymeric stent patterns with linking struts between rings that are designed to fail upon deployment of the stent are disclosed.03-15-2012
20120158123POLYMER STENT - The invention relates to a stent, comprising or consisting of amorphous polylactide. The invention relates further to the use of amorphous polylactide for stabilizing a stent and a method for producing a corresponding stent.06-21-2012
20120158122Removable stent and method of production - A removable porous stent is disclosed, which can be placed in tubular structures. In at least one embodiment, it can be placed at locations, which are unsuitable for permanent stents, like across important branches in the vasculature preferably in combination with anticoagulation. The walls of the stent are freely permeable for the blood flow. A temporary stent can be used during treatment of dissections with involvement of side branches. The dissected membrane is relocated to its original place and held in place by the stent until the healing process has reattached the membrane. At this point the stent will be removed. The removable stent can also be used, in at least one embodiment, as a carrier of chemotherapy and/or radiation to be placed in tubular structures for local treatment of cancer. The time for treatment is controlled and finished at removal. This approach will give the possibility to increase dosages and reduce side effects. In at least one embodiment, the stent is formed by at least one continuous thread arranged in interconnected loops and having a reversible bind-off at one end of the tubular body, mechanically securing each loop at said end of the tubular body apart from a single releasable loop. This loop is preferably extended beyond the tubular structure of the stent enabling an initiation of the removal at a distance from the treatment site.06-21-2012
20120158124STENTS HAVING RADIOPAQUE MESH - A stent including a mesh made of strands. The mesh has at least one radiopaque strand and at least one non-radiopaque strand, and the at least one radiopaque strand and the at least one non-radiopaque strand each have different diameters. Each strand has an index of wire stiffness EI, where EI is the mathematical product of the Young's modulus (E) and the second moment of area (I). The EI of all strands in the mesh is no more than five times the EI of the strand having the smallest EI of any of the strands.06-21-2012
20120071960ARTIFICIAL BLOOD VESSEL AND ARTIFICIAL BLOOD VESSEL SYSTEM - An artificial blood vessel includes a flexible tube and a structure provided at one end portion of the tube and capable of being deformed to a first outside diameter and a second outside diameter greater than the first outside diameter, wherein the tube is provided with a lock part which is locked at a desired position when the tube is folded back from its other end portion to the inside.03-22-2012
20110082537TRANSVASCULAR NEURAL STIMULATION DEVICE - This document discusses, among other things, apparatus, systems, and methods for transvascularly stimulation of a nerve or nerve trunk. In an example, an apparatus is configured to transvascularly stimulate a nerve trunk through a blood vessel. The apparatus includes an expandable electrode that is chronically implantable in a blood vessel proximate a nerve trunk. The expandable electrode is configured to abut a predetermined surface area of the vessel wall along a predetermined length of the vessel. An electrical lead is coupled to the expandable electrode. An implantable pulse generator is coupled to the lead and configured to deliver an electrical stimulation signal to the electrode through the lead. In an example method, an electrical signal is delivered from an implanted medical device to an electrode chronically implanted in a blood vessel proximate a nerve trunk to transvascularly deliver neural stimulation from the electrode to the nerve trunk.04-07-2011
20100179639VASCULAR IMPLANT - A vascular implant derived from natural vascular tissue material, wherein the vascular implant is substantially free of non-fibrous tissue proteins, cells and cellular elements and lipids or lipid residues and comprises collagenous material displaying the original fibre architecture and molecular ultrastructure of the natural vascular tissue material from which it is derived.07-15-2010
20110066224REPOSITIONABLE ENDOLUMINAL SUPPORT STRUCTURE AND ITS APPLICATIONS - An endoluminal support structure includes strut members interconnected by swivel joints to form a series of linked scissor mechanisms. The structure can be remotely actuated to compress or expand its shape by adjusting the scissor joints within a range of motion. In particular, the support structure can be repositioned within the body lumen or retrieved from the lumen. The support structure can be employed to introduce and support a prosthetic valve within a body lumen.03-17-2011
20110066223Bioabsorbable Stent With Time Dependent Structure And Properties - A bioabsorbable polymeric stent with time dependent structure and properties and methods of treating a diseased blood vessel with the bioabsorable polymeric stent are disclosed. The structure and properties of the stent change with time and allow the vessel to be restored to a natural unstented state03-17-2011
20110066222Polymeric Stent and Method of Making Same - A stent may be formed from a PLLA tubular polymer construct that is deformed in a blow mold. A desirable polymer morphology resulting in improved stent performance is obtained with a selected radial axial expansion ratio from about 20% to about 70%, a selected radial expansion ratio from about 400% to about 500%, a selected axial rate of deformation propagation at or about 0.3 mm/minute, a selected expansion pressure at or about 130 psi, and a selected expansion temperature that does not exceed 200 deg F. The tubular polymer construct may also be made of PLGA, PLLA-co-PDLA, PLLD/PDLA stereocomplex, and PLLA-based polyester block copolymer containing a rigid segment of PLLA or PLGA and a soft segment of PCL or PTMC.03-17-2011
20090082848STENT - A stent includes a plurality of first portions arranged in a longitudinal direction, and second portions each disposed between the adjacent first portions. Each of the first portions is expandable and contractible in a radial direction, and each of the second portions allows a whole of the stent to curve in the longitudinal direction. When the first portion is expanded in the radial direction, the longitudinal length of the first portion is decreased, but spacing between the adjacent first portions is increased.03-26-2009
20110106236Temporal Intraluminal Stent, Methods of Making and Using - A biodegradable polymer stent with radiopacity and a method of making and using a stent with enhanced mechanical strength and/or controlled degradation for use in a bodily lumen is described.05-05-2011
20100094403MEDICAL DEVICE - A stent deployment device comprises an elongate catheter shaft (04-15-2010
20120232643STENT FABRICATION VIA TUBULAR CASTING PROCESSES - Tubular casting processes, such as dip-coating, may be used to form substrates from polymeric solutions which may be used to fabricate implantable devices such as stents. The polymeric substrates may have multiple layers which retain the inherent properties of their starting materials and which are sufficiently ductile to prevent brittle fracture. Parameters such as the number of times the mandrel is immersed, the duration of time of each immersion within the solution, as well as the delay time between each immersion or the drying or curing time between dips and withdrawal rates of the mandrel from the solution may each be controlled to result in the desired mechanical characteristics. Additional post-processing may also be utilized to further increase strength of the substrate or to alter its shape.09-13-2012
20120232644STENT FABRICATION VIA TUBULAR CASTING PROCESSES - Tubular casting processes, such as dip-coating, may be used to form substrates from polymeric solutions which may be used to fabricate implantable devices such as stents. The polymeric substrates may have multiple layers which retain the inherent properties of their starting materials and which are sufficiently ductile to prevent brittle fracture. Parameters such as the number of times the mandrel is immersed, the duration of time of each immersion within the solution, as well as the delay time between each immersion or the drying or curing time between dips and withdrawal rates of the mandrel from the solution may each be controlled to result in the desired mechanical characteristics. Additional post-processing may also be utilized to further increase strength of the substrate or to alter its shape.09-13-2012
20120232642Punching-based stent and its manufacturing method - The present invention is to provide a stent comprising a main body or at least a strut and a principal manufacturing method by means of one punching die for precision punching machining without a follow-up rolling & precision welding step in order to fulfill improved yield rate, mass production, effectively curtailed throughput time and manufacturing cost, and stent's lowered price benefiting more patients.09-13-2012
20120123522METHOD OF TREATING A DILATED VENTRICLE - A method of reducing ventricular dilation comprises placing one or more cardiac bridges into vessels extending along a length of the ventricle. Each cardiac bridge preferably includes a pair of anchors and a bridge member secured therebetween. The tension in the bridge member compresses the ventricle and thereby reduces the dilation along the ventricle wall. In another embodiment, the bridge member is tensioned to reshape the left ventricle for reducing tension on the chordae tendinae in the heart for improving valve function.05-17-2012
20090132024Vascular Prosthesis for Aneurysms, Set of Vascular Prostheses, Method for Manufacturing a Vascular Prosthesis and Method for Inserting a Vascular Prosthesis - The present invention relates to a vascular prosthesis for aneurysms (05-21-2009
20090132023METHODS AND APPARATUS WITH POROUS MATERIALS - A method and apparatus according to various aspects of the present invention comprises a system having multiple pores. In one embodiment, the system comprises a medical device for insertion into an organism, comprising a main structure and a porous portion on the main structure.05-21-2009
20120123523REINFORCING RING - A reinforcing ring (05-17-2012
20100241214OPTIMIZED STENT JACKET - A method of stenting, comprises: implanting a stent assembly in a vessel of a subject, the stent assembly, including: a stent jacket, comprising an expansible mesh structure, formed of fibers of a diameter between about 7 micrometers and about 18 micrometers, the diameter having a property of forming a substantially stable layer of endothelial cells, covering the fibers, thus reducing platelet aggregation, and an expansible stent, operatively associated with the stent jacket. The method further comprises administering to the subject an active pharmaceutical ingredient (API) comprising a platelet aggregation reducer for a shortened time period, not exceeding six months, the shortened time period being a consequence of the property. In accordance with some embodiments, the administration of a platelet aggregation.09-23-2010
20090088833DOUBLE WALL STENT WITH RETRIEVAL MEMBER - A double wall stent assembly is described in which an inner stent is deployed within an outer stent. The inner stent may be attached to the outer stent by various mechanisms, including a male and female receiving end or by an adhesive. After the inner stent has become clogged, a retrieval member may be inserted into the lumen of the inner stent to detach the inner stent from the outer stent. The clogged inner stent is thereafter removed from the body lumen leaving the outer stent in place.04-02-2009
20100249900Drug eluting medical implant with porous surface - An implant is proposed, in particular made from a base material including a biodegradable metal and/or a biodegradable metal alloy, wherein the implant includes a coating made of crystalline calcium phosphate and/or amorphous calcium phosphate.09-30-2010
20100249901CYLINDRICAL STENT - The present invention relates to a cylindrical stent, which is a self-expanding type medical appliance for expanding the lumen of a blood vessel or esophagus that is stenosed, more specifically a cylindrical stent made of metal material forming a plurality of peak portions P and valley portions B and having a lengthwise axis. The cylindrical stent is characterized in that the end portions A of the peak portions forming both of the distal portions of the cylindrical stent are bent in the inward direction of the cylindrical stent. The present invention can effectively prevent the problem that a false blood vessel is formed as the vessel wall is exfoliated, broken or damaged due to contact between the distal portion of the cylindrical stent arid the vessel wall, and has an effect of effectively preventing the problem that inflammation occurs at the contact portion due to contact between the lumen wall of an esophagus, etc. and the distal portion of the cylindrical stent.09-30-2010
20100204777INHIBITORY CELL ADHESION SURFACES - Nanostructured surfaces on selected substrates are described which are highly resistant to cell adhesion. Such surfaces on medical implants inhibit fibroblast adhesion particularly on nanorough titanium deposited on smooth silicone surfaces. The nanostructured deposited metal coatings can also be engineered so that several cell types, including endothelial, osteoblast, and fibroblast cells, show little if any tendency to attach to the coated surface in vivo.08-12-2010
20120130477VASCULAR PROSTHESIS AND RELEVANT METHOD FOR REALISING THEREOF - The present invention relates to a tubular shaped vascular prosthesis (05-24-2012
20120165919METHODS AND DEVICES FOR TREATMENT OF VASCULAR DEFECTS - Devices and methods for treatment of a patient's vasculature with some embodiments configured for delivery with a microcatheter for treatment of the cerebral vasculature of a patient. Some embodiments include thin permeable membranes configured to occlude blood flow therethrough.06-28-2012
20120165918Woven Prosthesis and Method for Manufacturing the Same - A woven prosthesis, such as a woven vascular graft, woven from warp and weft yarns. Velour warp yarns forming the prosthesis are selectively incorporated into a base layer of the prosthesis so as to provide a bulbous section without compromising the porosity of the prosthesis.06-28-2012
20100049301Lattice Part Made of Metal and Method for the Production of a Lattice Part - We describe a lattice part made of metal and a method for producing a lattice part made of metal or a metal alloy. The lattice has a thickness of less than 1 mm at a size of the gaps of less than 50 mm02-25-2010
20120083872DEVICE AND METHOD FOR TACKING PLAQUE TO A BLOOD VESSEL WALL - A tack device for holding plaque against blood vessel walls in treating atherosclerotic occlusive disease can be formed as a thin, annular band of durable, flexible material. The tack device may also have a plurality of barbs or anchoring points on its outer annular periphery. The annular band can have a length in the axial direction of the blood vessel walls that is about equal to or less than its diameter as installed in the blood vessel. A preferred method is to perform angioplasty with a drug eluting balloon as a first step, and if there is any dissection to the blood vessel caused by the balloon angioplasty, one or more tack devices may be installed to tack down the dissected area of the blood vessel surface, in order to avoid the need to install a stent and thereby maintain a ‘stent-free’ environment.04-05-2012
20100204778POLYMER-BASED STENT ASSEMBLY - Methods for preparing a polymer-based stent assembly comprising an inflatable balloon catheter and a polymer-based stent resistant to relaxation-related negative recoil are provided. The methods comprise heating a polymeric cylindrical device which is at a final predetermined shape and diameter to a temperature sufficiently above the glass transition temperature (Tg) of the polymer and for a time sufficient to erase any memory of previous processing of the polymeric cylindrical device and then quenching the polymeric cylindrical device to provide an educated polymeric cylindrical device having a memory of the final predetermined diameter and shape, mounting the educated cylindrical device on an inflatable balloon catheter, reducing the diameter of the educated cylindrical device by heating to a temperature at or slightly above the Tg of the polymer while evenly applying pressure on the exterior surface of the wall of the cylindrical device, and then cooling the cylindrical device below the Tg of the polymer to provide a stent assembly comprising an inflatable balloon catheter and an expandable, educated, polymeric stent snugly and stably disposed thereon. Assemblies comprising an inflatable balloon and a polymer based stent that is substantially resistant to relaxation related recoil mounted snugly on the balloon are also provided.08-12-2010
20120136427IMPLANTABLE MEDICAL DEVICES HAVING CONTROLLED SURFACE PROPERTIES FOR IMPROVED HEALING RESPONSE - An implantable medical device that is fabricated from materials that present a blood or body fluid or tissue contact surface that has controlled heterogeneities in material constitution. An endoluminal stent-graft and web-stent that is made of a monolithic material formed into differentiated regions defining structural members and web regions extending across interstitial spaces between the structural members. The endoluminal stent-graft is characterized by having controlled heterogeneities at a the blood flow surface of the stent.05-31-2012
20100174357Vascular Prosthesis of Varying Flexibility - A vascular prosthesis including a tubular body and a plurality of independent support members disposed on a surface of the tubular body. Spacing between the independent support members is varied to vary the flexibility of the vascular prosthesis.07-08-2010
20120253452THORACIC GRAFT HAVING YARN MODIFICATIONS - An endoluminal prosthesis (10-04-2012
20100049302STENT FOR EXPENDING INTRA LUMINAL - The present invention relates to a stent for intraluminal expansion. The stent for intraluminal expansion comprises an inner stent A, an outer stent B and fixing threads C for fixing these stents as one unit. The outer stent B is inserted over the inner stent A in such a way that the space portions of the inner stent A and the space portions of the outer stent B are alternated with each other, so the outer surface of the inner stent and the inner surface of the outer stent are in close contact with each other, and both ends of the outer stent and inner stent are fixed as one unit by fixing threads C. According to the stent for intraluminal expansion of the present invention, in which form recoverability of each of the inner stent A and the outer stent B is excellent, expansion is easy after it is inserted into the lumen body because the cylindrical film membrane is not fixed by fixing thread C, and the space portions Id of the inner and outer stents are overlapped alternately with each other so that it is possible to effectively prevent cancer cells, etc. from penetrating into the lumen.02-25-2010
20100049299MAGNESIUM-BASED ALLOY WITH IMPROVED COMBINATION OF MECHANICAL AND CORROSION CHARACTERISTICS - Multi-component magnesium-based alloy consisting essentially of about 1.0-15.0 wt. % of scandium, about 0.1-3.0 wt. % of yttrium, about 1.0-3.0 wt. % of rare-earth metal, about 0.1-0.5 wt. % of zirconium. Purity degree of magnesium base is not less of 99.995 wt. %. Impurities of Fe, Ni and Cu do not exceed 0.001 wt. % of everyone, the contents of other impurity in an alloy does not exceed 0.005 wt. %. The alloy demonstrates an improved combination of strength, deformability and corrosion resistance at room temperature. The alloy does not contain harmful and toxic impurities. The alloy can be used in the various practical applications demanding a combination of high strength, deformability and corrosion resistance, preferably in the field of medicine.02-25-2010
20100298925SPINULOSE METAL SURFACES - Spinulose metal surfaces are produced by a modified nanoplasma cyclic deposition process. The unique spinulose surfaces are highly adherent toward polymer and bioactive molecules and cells, including osteoblast, fibroblast and endothelial cells. The nanostructured spinulose surfaces can be coated with a wide range of polymers to form polymer surface coatings that are particularly useful on implants, catheters, guidewires, stents and other medical devices intended for in vivo applications.11-25-2010
20120179237SPRAY SYSTEM AND METHOD OF MAKING PHASE SEPARATED POLYMER MEMBRANE STRUCTURES - A spray system and method of using such spray system to fabricate a polymer membrane structure for use as a vascular graft or tissue engineered scaffold is provided. Generally, this spray system includes the use of at least two spray apparatus to apply different polymer and solvent mixtures to the outer surface of a mandrel to form a blended layer. Upon curing of the blended layer, phase separation occurs leading to the formation of a polymer membrane structure having variable properties along at least a portion of its longitudinal axis.07-12-2012
20090062904STENT COATING - An expandable stent for use within a body passageway having a body member with two ends and a wall surface disposed between the ends. The body member has a first diameter to permit delivery of the body member into a body passageway and a second expanded diameter. The surface of the stent is coated with a biological agent and a polymer which controls the release of the biological agent.03-05-2009
20120253451IMPLANTABLE MEDICAL DEVICES - A medical device includes a balloon catheter having an expandable member, e.g., an inflatable balloon, at its distal end and a stent or other endoprosthesis. The stent is, for example, an apertured tubular member formed of a polymer and is assembled about the balloon. The stent has an initial diameter for delivery into the body and can be expanded to a larger diameter by inflating the balloon.10-04-2012
20120253449Stent - The present invention discloses a stent for supporting a sidewall of a lumen which contains a first fluid. The stent comprises a stent body, a film and a photosensitizing layer. The stent body is disposed inside the lumen. The film is adapted to be penetrated by a light and covers the stent body. The photosensitizing layer is disposed on an outer surface of the film for receiving the light to generate a first object, and the film separates the photosensitizing layer and the first fluid. The film and the photosensitizing layer of the present invention can greatly reduce the needed dosage of the photosensitizer while maintaining the effective concentration of the photosensitizer around tumor cells.10-04-2012
20120253450Prosthesis Adapted for Placement Under External Imaging - An expandable prosthesis having an imageable structure comprising one or more elements visually distinguishable by an external (e.g., radiographic or ultrasonic) imaging system, the structure being located about a first axis that corresponds to a structural feature of the prosthesis that is configured to perform a specific function particular to that axis. The imageable structure is configured to assist in the rotational orientation of the prosthesis during placement within the implantation site. In one embodiment, the prosthesis comprises a venous valve that includes imageable elements or structure, such as a pair of radiopaque markers, that defines the orifice of the valve structure such that the orifice can be oriented with a particular anatomical feature under imaging, such as to align the orifice with the long axis of the vessel.10-04-2012
20090319024REMOVABLE STENT AND METHOD OF MANUFACTURE THEREOF - A removable stent may include, for example, an extension or protrusion, or a cut or angled end, which may be easily grasped for removal by for example forceps. A stent may be molded to form such graspable extensions, or may be cut and/or melted or otherwise deformed as part of manufacture.12-24-2009
20120226345BIODEGRADABLE ENDOPROSTHESES AND METHODS FOR THEIR FABRICATION - Biodegradable endoprostheses are formed from amorphous polymers having desirable biodegradation characteristics. The strength of such amorphous polymers is enhanced by annealing to increase crystallinity without substantially increasing the biodegradation time.09-06-2012
20120259405Radial Radiopaque Markers - A deployable medical device having at least one radiopaque marker is herein disclosed. In particular, the deployable medical device comprises a bio-absorbable stent or expandable medical balloon. Upon insertion of the deployable medical device, the at least one radiopaque marker is inserted into adjacent tissue, where it will remain even after the deployable medical device has been removed.10-11-2012
20120191176MEDICAL IMPLANT - A medical implant having a wall, which can be transferred from a compressed to an expanded state and includes a mesh structure formed of first struts, wherein the mesh structure has closed cells, each having a retaining element, which is adapted to anchor the expanded mesh structure in a vessel. The retaining element has at least two second struts which are connected to one another and form a tip which projects into the cell, and are connected to the first struts of the cell.07-26-2012
20120191175Tubular Stent with Rotatable Connections and Method of Making - A tubular stent includes a plurality of bands aligned generally along a common longitudinal axis. A first band has a plurality of first crowns and a second band adjacent to the first band has a plurality of second crowns. A connecting ring connects the first band to the second band, wherein one of the first crowns is rotatably disposed through a lumen of the connecting ring and one of the second crowns is fused to the wall of the connecting ring outside of the lumen of the connecting ring. Methods of making tubular stents with rotatable connections are also disclosed.07-26-2012
20120259404Stent - In one embodiment according to the present invention, a stent is described having a generally cylindrical body formed from a single woven nitinol wire. The distal and proximal ends of the stent include a plurality of loops, some of which include marker members used for visualizing the position of the stent. In another embodiment, the previously described stent includes an inner flow diverting layer.10-11-2012
20100331959METHOD OF RADIALLY EXPANDING A TUBULAR ELEMENT - The invention relates to a method of radially expanding a tubular element extending into a wellbore formed in an earth formation, the tubular element including a first layer and a second layer extending around the first layer, said layers being separable from each other. The method comprises inducing each layer to bend radially outward and in an axially reverse direction so as to form an expanded tubular section extending around a remaining tubular section of the tubular element, wherein each layer has a respective bending zone in which the bending occurs, and increasing the length of the expanded tubular section by inducing the respective bending zones of the layers to move in an axial direction relative to the remaining tubular section. The layers in the respective bending zones are separate from each other so as to define an axial space between the layers.12-30-2010
20080300673RADIOPAQUE COMPOSITIONS, STENTS AND METHODS OF PREPARATION - The invention relates to an implantable radiopaque stent adapted to be disposed in a body lumen. In one aspect of the invention, a plurality of elongate filaments including one or more radiopaque filaments are arranged to form a hollow tubular structure having a tubular wall that defines an inner surface and an outer surface and opposing first open end and second open end. One of the open ends of the stent is formed by an intersection of adjacent filament ends. A radiopaque compound is applied to the intersection, the radiopaque compound comprising radiopaque material and polymeric material. The radiopaque compound and radiopaque filament provide improved external imaging of the tubular structure on imaging equipment.12-04-2008
20080300669In situ trapping and delivery of agent by a stent having trans-strut depots - A method of delivering an agent into a bodily lumen, the method comprising: implanting an implantable medical device into a treatment site of a lumen, the device having an abluminal face and a luminal face, wherein the device includes depots that extend from an open end at a luminal face to an open end at an abluminal face; and introducing an agent into the open end of the depots at the luminal face such that the agent is delivered to the treatment site through the open end at the abluminal face.12-04-2008
20080300672Devices and Methods for Magnetic Tissue Support - Devices and methods are disclosed for providing tissue support within the body. A metallic component and a magnetic component are used and allowed to interact through the body of the tissue such that the attractive forces between these components provides the external support needed by that tissue to properly function within its position. Such a technique is described with respect to the particular example of correction of aneurysms.12-04-2008
20080300671Stent having high expansion ratio - An expandable frame movable between a collapsed configuration and an expanded configuration includes at least one first member. The at least one first member includes a plurality of substantially parallel first struts and a plurality of second struts. Each second strut is coupled between adjacent first struts and is substantially perpendicular to adjacent first struts with the frame in the collapsed configuration defining a plurality of open cells to facilitate expansion of the frame.12-04-2008
20080300668STENT/FIBER STRUCTURAL COMBINATIONS - A plurality of endoluminal segments axially connected by fiber bridges is disclosed. The endoluminal segments may either be balloon-expandable or self-expanding, with the preferred embodiment being superelastic nitinol. The intraluminal segments may possess a textured surface or at least one geometric feature per segment, preferably located at the apex of a strut pair comprising the intraluminal segment, preferably capable of serving as an anchoring point for the fiber bridges. These geometric features may transmit axially compressive loads during deployment from a device such as a catheter, and may further be capable of interlocking the endoluminal segments when constrained within a device such as a catheter. The fibers comprising the bridges may be polymeric, silk, collagen, bioabsorbable, or a blend thereof. The fiber network comprising the bridges may be regularly oriented, randomly oriented, localized, or continuous. Moreover, the intraluminal segments and fiber bridges may be individually impregnated with therapeutic material, or may both be impregnated with therapeutic material.12-04-2008
20110004289METHODS AND APPARATUS FOR A STENT HAVING AN EXPANDABLE WEB STRUCTURE - The present invention provides a stent comprising a tubular flexible body having a wall with a web structure that is expandable from a contracted delivery configuration to deployed configuration. The web structure comprises a plurality of neighboring web patterns, where each web patterns is composed of adjoining webs, and the web patterns are interconnected. Each adjoining web comprises a central section interposed between two lateral sections to form concave or convex configurations.01-06-2011
20110004288INTRAVASCULAR IMPLANTABLE DEVICE HAVING INTEGRATED ANCHOR MECHANISM - Devices, systems and methods are provided for an intravascular implantable device having an integrated anchor mechanism that can be deployed by compressing the anchor in an axial direction. Various embodiments address the various issues presented by the prior art and/or improve upon the prior art devices, methods and systems for anchoring an intravascular implantable device within a vessel.01-06-2011
20090171439Temporary Stent - Temporary stent having a plurality of ring elements arranged adjacent to each other, with said stent being capable of being explanted after it has been implanted in a body lumen, with all ring elements (07-02-2009
20120239135STENTS INCLUDING POLY(L-LACTIDE) FORMULATIONS THAT MINIMIZE MOLECULAR WEIGHT DROP DURING PROCESSING - A stent scaffolding including a polymer formulation comprising PLLA and polymandelide is disclosed. The polymandelide reduces the molecular weight drop during processing, particularly during sterilization. The stent scaffolding can further include one or more additional stabilizing agents that additionally reduce the molecular weight drop during processing.09-20-2012
20120239134APPARATUS AND METHODS TO ENHANCE BONDING IN ENDOLUMINAL PROSTHESES - The present embodiments provide an endoluminal prosthesis comprising a first membrane having a lumen for allowing fluid flow, and a stent having contracted and expanded states. At least one surface enhancement member, separate from the stent, is secured to the stent prior to a coxial overlapping state of the stent and the first membrane. The at least one surface enhancement member has stronger bonding properties with the first membrane, relative to bonding properties of bare surfaces of the stent with the first membrane, when the stent and the first membrane are in the coaxially overlapping state.09-20-2012
20120239133Surgical Implant Devices and Methods for Their Manufacture and Use - Sealable and repositionable implant devices are provided with one or more improvements that increase the ability of implants such as endovascular grafts to be precisely deployed or re-deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and/or with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant. A surgical implant includes an implant body and a selectively adjustable assembly attached to the implant body, having adjustable elements, and operable to cause a configuration change in a portion of the implant body and, thereby, permit implantation of the implant body within an anatomic orifice to effect a seal therein under normal physiological conditions.09-20-2012
20110130825MODULAR ENDOGRAFT DEVICES AND ASSOCIATED SYSTEMS AND METHODS - Modular endograft devices and associated systems and methods are disclosed herein. In several embodiments, an endograft system can include a first endograft device and a second endograft device that each include an integrated frame, a cover and a lumen within the cover. Each endograft device further includes a superior portion and an inferior portion. The superior portion can have a convexly curved outer wall and a septal wall. The first and second endograft devices can be configured to extend into a low-profile configuration with a first cross-sectional dimension and a first length and self-expand into an expanded configuration with a second cross-sectional dimension greater than the first cross-sectional dimension and a second length less than the first length. In the expanded configuration, the septal walls can press against each other and form a septum between the lumens of the first and second endograft devices.06-02-2011
20110130827VASCULAR PROTECTIVE DEVICE - A medical device to protect and/or heal a diseased and/or injured area in the body passageway.06-02-2011
20110130826MODULAR ENDOGRAFT DEVICES AND ASSOCIATED SYSTEMS AND METHODS - Modular endograft devices and associated systems and methods are disclosed herein. In several embodiments, an endograft system can include a first endograft device and a second endograft device that each include an integrated frame, a cover and a lumen within the cover. Each endograft device further includes a superior portion and an inferior portion. The superior portion can have a convexly curved outer wall and a septal wall. The first and second endograft devices can be configured to extend into a low-profile configuration with a first cross-sectional dimension and a first length and self-expand into an expanded configuration with a second cross-sectional dimension greater than the first cross-sectional dimension and a second length less than the first length. In the expanded configuration, the septal walls can press against each other and form a septum between the lumens of the first and second endograft devices.06-02-2011
20110130824MODULAR ENDOGRAFT DEVICES AND ASSOCIATED SYSTEMS AND METHODS - Modular endograft devices and associated systems and methods are disclosed herein. In several embodiments, an endograft system can include a first endograft device and a second endograft device that each include an integrated frame, a cover and a lumen within the cover. Each endograft device further includes a superior portion and an inferior portion. The superior portion can have a convexly curved outer wall and a septal wall. The first and second endograft devices can be configured to extend into a low-profile configuration with a first cross-sectional dimension and a first length and self-expand into an expanded configuration with a second cross-sectional dimension greater than the first cross-sectional dimension and a second length less than the first length. In the expanded configuration, the septal walls can press against each other and form a septum between the lumens of the first and second endograft devices.06-02-2011
20110130822Bioabsorbable Polymeric Compositions and Medical Devices - The present invention comprises a stent forming a plurality of meandering elements comprising a blend formed from a polymer. The polymer comprises poly-L-lactide, poly-D-lactide or mixtures thereof and a copolymer moiety comprising poly-L-lactide or poly-D-lactide linked with ε-caprolactone or trimethylcarbonate. The poly-L-lactide or poly-D-lactide sequence in the copolymer moiety is random with respect to the distribution of ε-caprolactone or trimethylcarbonate and the copolymer moiety molecular weight ranges from about 1.2 IV to about 4.8 IV. The meandering elements may be stretched to a modulus ranging from about 250000 PSI to about 550,000 PSI, one segment of the meandering element has a decreased cross-sectional area and may have a wide-angle X-ray scattering (WAXS) 2θ values of ranging from about 1 to about 35. In various embodiment, two, three or n segments of the meandering element have a decreased cross-sectional area and may also have a wide-angle X-ray scattering (WAXS) 2θ values of ranging from about 1 to about 35 after stretching. In another embodiment, all segments of the meandering element have a decreased cross-sectional area and may also have a wide-angle X-ray scattering (WAXS) 2θ values of ranging from about 1 to about 35 after stretching. The meandering element may comprise a helical winding, a circumferential winding or stent ringlet. The properties of the bioabsorbable polymers allow for both crimping and expansion of the stent. The crystal properties of the bioabsorbable polymers may change during crimping and/or expansion allowing for improved mechanical properties such as tensile strength and slower degradation kinetics.06-02-2011
20120265290INFLATABLE INTRALUMINAL GRAFT - A collapsible stent graft for aortic aneurysms includes a collapsible inner tubular member (10-18-2012
20120265289ENDOLUMINAL DEVICE WITH KINK-RESISTANT REGIONS - An endoluminal prosthesis having a tubular graft comprising a first biocompatible material having a first weave density comprising yarns aligned in a first direction interwoven with yarns aligned in a second direction, and a second biocompatible material having a second weave density less than the first weave density comprising yarns aligned in a first direction interwoven with yarns aligned in a second direction, the second biocompatible material spirally positioned throughout the entire length of the tubular graft around a central axis with respect to the first biocompatible material. An elongate member is attached along the length of the tubular graft. The tubular graft includes first regions comprising the first biocompatible material and second regions containing the second biocompatible material. The elongate member is attached to the first regions of the tubular graft.10-18-2012
20080288046Method of Attaching Radiopaque Markers to Intraluminal Medical Devices, and Devices Formed Using the Same - A method of attaching radiopaque markers to an intraluminal medical device frame formed from a shape memory metal or alloy thereof, the process conducted during the shape recovery process of said shape memory metal or alloy thereof.11-20-2008
20120271402EMERGENCY VASCULAR REPAIR SYSTEM AND METHOD - A system to deliver a prosthesis for repair of a transected body vessel is described herein. The system can have a prosthesis and a plurality of distinct strands. A releasable loop can be formed at a distal end of each strand and positioned to retain one of a plurality of portions of the prosthesis in a compressed configuration. Each portion of the prosthesis can be independently movable between the compressed configuration and an expanded configuration. Retraction of the proximal end or severing the loop of any one of the strands can cause the corresponding loop to release to allow the corresponding portion of the prosthesis to expand from the compressed configuration to the expanded configuration. The prosthesis can couple two vessel portions of the transected vessel together to allow for blood perfusion and maintain hemostasis.10-25-2012
20120323306Removable Covering for Implantable Frame Projections - Medical devices for implantation in a body vessel, and methods of using and making the same, are provided. A medical device can include a frame with one or more projections, each of which can be covered with a biocompatible, water-soluble removable material. The projections can be barbs positioned to engage the interior wall of a body vessel or to attach a material, such as a valve leaflet or graft, to the frame. The removable material can be dissolved within a body vessel upon implantation to expose the covered projection. Methods of making an implantable medical device and methods of treating a subject are also disclosed.12-20-2012
20120271403TUBULAR STRUCTURE AND METHOD FOR MAKING THE SAME - A tubular structure and method for making a tubular structure are provided, where the tubular structure includes at least one layer of braided strands. In general, at least one portion of the braided strands exhibits a braid pattern of crests and troughs (e.g., a wave pattern, which may include sinusoidal, square, and/or sawtooth waves) along a length of the tubular structure. The wave pattern can be created by rotating the mandrel onto which the tubular structure is braided during the braiding process, such as by angularly oscillating the mandrel about its longitudinal axis or about its transverse axis. As a result, the tubular structures may have increased radial strength, collapse resistance, torque transmission, column strength, and kink resistance. The tubular structures may be used in medical devices, such as stent-grafts, as well as in other medical and non-medical devices, such as in hoses, tubing, filters, and other devices.10-25-2012
20120330403INTRAVASCULAR STENT - The invention is directed to an expandable stent for implanting in a body lumen, such as a coronary artery, peripheral artery, or other body lumen. The invention provides for an intravascular stent having a plurality of cylindrical rings connected by undulating links. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen. The stent can be compressed or crimped onto a catheter to a very low profile since the peaks that are adjacent the curved portion of the undulating link are shorter than other peaks in the same cylindrical ring to prevent overlap yet still achieve a very low profile, tightly crimped stent onto a catheter.12-27-2012
20120271404PATIENT-SPECIFIC MODIFIABLE STENTS - Implantable stents and stent systems that include one or more features that can be selectively modified at the point of use, i.e., in the surgical suite, etc. The selectively modifiable features may take a variety of forms such as, e.g., length, the presence of flaps, voids, etc.10-25-2012
20120323305STENTS INCORPORATING A PLURALITY OF STRAIN-DISTRIBUTION LOCATIONS12-20-2012
20120323304BIASED ENDOLUMINAL DEVICE - An endoluminal device can comprise a flexible tubular wall and a frame member. The frame member can be comprised of a shape-memory material having sides with protrusions which are partially or substantially flattened when formed together with the flexible tubular wall to thereby create a bias in the side wall of the endoluminal device that resists deformation from a desired device profile during crush loading and is thereby resistant to invaginations when deployed.12-20-2012
20110218615Stent With Multi-Crown Constraint and Method for Ending Helical Wound Stents - A stent includes a wave form having a plurality of struts and a plurality of crowns with each crown connecting two adjacent struts. The wave form is wrapped around a longitudinal axis to define a plurality of turns. The stent includes a first connection that connects an end of the wave form to an adjacent crown in a first turn that defines an end of the stent, and a second connection that connects a first crown of the wave form to an adjacent crown in a second turn.09-08-2011
20110218614Stent With Sinusoidal Wave Form and Orthogonal End and Method for Making Same - A stent includes a wave form that includes a plurality of struts and a plurality of crowns. The wave form is wrapped around a longitudinal axis so as to define a plurality of turns, including a first turn disposed at a first angle and a second turn disposed at a second angle relative to the longitudinal axis. A first connection connects an end of the wave form that started the first turn to an adjacent crown of the wave form that completed the first turn, a second connection connects a first crown of the second turn to an adjacent crown that completed the second turn, and a third connection connects a crown of the first turn to an adjacent crown of the second turn. The wave form is disrupted between the first turn and the second turn.09-08-2011
20110238151SURFACE TREATED BIOERODIBLE METAL ENDOPROSTHESES - An endoprosthesis includes an expandable tubular body defined by a plurality of struts. In some embodiments, the expandable tubular body includes a bioerodible metal that has at least a first surface region and a second surface region. The first and second surface regions can have different surface oxide compositions. In some embodiments, the first portion has a thermally altered microstructure and the second portion has a wrought microstructure. The thermally altered microstructure can be a cast microstructure comprising dendritic grains. The first portion forms at least a portion of an outer surface of the expandable tubular body. In some embodiments, the expandable tubular body includes iron or a bioerodible iron alloy and at least one surface of the expandable tubular body includes a substantially uniform coating of iron(III) oxide.09-29-2011
20110238155STENT FORMED FROM BIOERODIBLE METAL-BIOCERAMIC COMPOSITE - Medical devices and methods of fabricating such medical devices, such as stents, formed at least in part from a metal matrix composite including bioceramic particles dispersed within an erodible metal are disclosed.09-29-2011
20110238154Intravascular Treatment Device - A collapsible treatment device (09-29-2011
20110238153ENDOPROSTHESES - Endoprostheses include an endoprosthesis wall that includes a surface layer that includes a metallic material and that defines a plurality of discrete pores. A porous material is disposed in one or more pores of the surface layer. The endoprostheses can, for example, deliver a therapeutic agent, such as a drug, in a controlled manner over an extended period of time.09-29-2011
20110238152Flat process of preparing drug eluting stents - The present invention provides a method of fabricating a drug delivery stent. In one embodiment, the method involves forming a stent pattern in a flat sheet, where the stent pattern includes reservoirs, generating a flat map of the reservoirs, filling the reservoirs with a composition based on the flat map, and then forming the filled stent pattern into a tubular shape and joining the sides. In another embodiment, the method involves forming a stent pattern in a flat sheet, generating a flat map of discrete portions of the stent pattern that are desirable locations for coating, coating the discrete portions with a composition based on the flat map, and then forming the coated stent pattern into a tubular shape and joining the sides. The invention provides advantages over current methods and drug-delivery stents in that it is faster, more accurate and more cost-efficient manufacturing process for fabricating drug delivery stents, that improves quality and consistency of drug delivery within and across batches of stents, and that permits automated a process of quality control. This method also allows for differential coating on the two surfaces of the stent struts, whereby the two sides are coated with different drugs and/or polymer combinations, or only one side of the strut is coated.09-29-2011
20110238150Bioerodible Medical Implants - An implantable medical device includes a bioerodible portion adapted to erode when exposed to a physiological environment. The bioerodible portion includes an alloy comprising at least 10 weight percent chromium and has an outer surface having a ratio of chromium oxide to chromium metal of less than 5. The bioerodible implantable medical device can be created by implanting metallic ions into an alloy including at least 10 weight percent chromium to define an outer surface of a medical implant, or precursor thereof.09-29-2011
20110238149ENDOPROSTHESIS - Endoprostheses and methods of making endoprostheses are disclosed. For example, endoprostheses are described that include an endoprosthesis body, a biodegradable metallic tie layer, and a polymer coating about the endoprosthesis body. The biodegradable tie layer and the polymer coating can have a high peel strength from the body.09-29-2011
20120089218HYDROGEL JACKETED STENTS - Hydrogel jacketed stents provide the ability to fill in the stent frame in vivo to at least partially cover the interior of the surface of the stent following deployment while having the convenience of attaching the jacket to the exterior of the stent. The hydrogel can be pleated and/or folder over the exterior of the stent to provide for extension of the stent without damaging the hydrogel. The hydrogel sheet can be secured at one or more points along the circumference to associate the sheet of hydrogel with the exterior surface of the stent frame. The stent can be conveniently delivered using similar technology as conventional stents if desired. The hydrogel can provide for drug delivery if desired.04-12-2012
20120089217MEDICAL IMPLANT, IN PARTICULAR A STENT, FOR IMPLANTATION IN AN ANIMAL BODY AND/OR HUMAN BODY - A medical implant (04-12-2012
20110276125Medical Devices, Methods of Producing Medical Devices, and Projection Photolithography Apparatus for Producing Medical Devices - Stents and other medical devices that can have specific geometric configurations (curves, contours, tapers) and/or patterns (e.g., grooves) thereon, methods of making such medical devices, and apparatuses for making such medical devices are disclosed. Projection photolithography is used to define patterns the medical devices. The methods can form grooves, ridges, channels, holes, wells, and other geometric patterns (e.g. parallelograms such as squares, rectangles and other trapezoids; triangles, pentagons, spirals, hexagons, etc.) on the surface of both the inner and outer diameters (e.g., on both the inner and outer surfaces) of stents or other cylindrical, tubular or curved-surface medical devices, allowing the manufacture of stents having customized geometry/contours on all surfaces, which can minimize endothelial surface disruption of blood flow.11-10-2011
20110276124BIOCORRODABLE IMPLANT IN WHICH CORROSION MAY BE TRIGGERED OR ACCELERATED AFTER IMPLANTATION BY MEANS OF AN EXTERNAL STIMULUS - The present invention relates to a biocorrodable implant in which corrosion may be triggered or accelerated after implantation by means of an external stimulus, the implant having a base body which is completely or partially composed of a biocorrodable metallic material, and the base body having a coating with a protective layer which is not biocorrodable. According to the invention, the implant has control elements which are configured in such a way that the protective layer, optionally in combination with the control elements, completely or partially encloses the base body so as to be impermeable to bodily medium, and the protective layer being to convertible to a form which is permeable to bodily medium as the result of a change in shape of the control elements which may be regulated and/or controlled by an external stimulus.11-10-2011
20110276123VASCULAR STENT DESIGN - This invention is directed to the design of radially expandable vascular stents to optimize hemodynamic flow characteristics that are favorable for the inhibition of stent-associated thrombosis, inflammation, and restenosis (neointimal formation) and that will reduce the risk of adverse events post-deployment.11-10-2011
20110282428BIODEGRADABLE COMPOSITE STENT - A biodegradable stent body is defined by a composite of a biodegradable polymer and a biodegradable metal insert. The composition, geometry, and location of the metal and polymer are selected for desirable stent performance.11-17-2011
20110319978BIODEGRADABLE COMPOSITE WIRE FOR MEDICAL DEVICES - A bimetal composite wire including, in cross-section, an outer shell or tube formed of a first biodegradable material and an inner core formed of a second biodegradable material. When formed into a stent, for example, the first and second biodegradable materials may be different, and may have differing biodegradation rates. In a first embodiment, the first biodegradable material of the shell may degrade relatively slowly for retention of the mechanical integrity of a stent during vessel remodeling, and the second biodegradable material of the core may degrade relatively quickly. In a second embodiment, the first biodegradable material of the shell may degrade relatively quickly, leaving a thinner structure of a second biodegradable material of the core that may degrade relatively slowly. The biodegradation rates may be inherently controlled, such as by selection of materials, and also may be mechanically controlled, such as by material thicknesses and the geometric configuration of the shell, core, or overall device. In any embodiment, the metallic scaffold may also be coated with a drug-eluting, biodegradable polymer, to further inhibit neointimal proliferation and/or restenosis.12-29-2011
20110319977BIOABSORBABLE IMPLANTS - A bioabsorbable implant including an elongated metallic element including more than 50% a metal substantially free of rare earth metals, with the elongated metallic element defining at least a portion of the bioabsorbable implant.12-29-2011
20120101564STENTS WITH ATTACHED LOOPED ENDS - An open frame prosthesis is formed with looped end terminations at its proximal and distal ends. At one end of the prosthesis, the filaments or strands are welded together in pairs to form strand couplings. A plurality of loop segments are connected to the strand couplings, one loop segment for each pair of adjacent strand couplings. In one version of the prosthesis, strands at the opposite end are bent to form looped ends. In another version, loop segments are connected to pairs of strand couplings at both ends of the prosthesis. The loop segments can be connected to the couplings by welding, fusion bonds, or tubes, which are either crimped or heat shrunk.04-26-2012
20120290072EMERGENCY VASCULAR REPAIR PROSTHESIS - A prosthesis system for repair of a transected body vessel is provided. The system can include first and second prostheses each including a tubular graft body and a support structure. Each prosthesis can be expandable between a compressed and an expanded configuration. In the expanded configuration, outer surfaces of the first and second prostheses can engage walls of the body vessel. The system can include a sleeve member formable into a tubular body. The first and second prostheses can be coupled to one another at a joint to form a coupled prosthesis. The sleeve member can receive the coupled prosthesis and cover the joint to inhibit leakage therefrom. The prosthesis system can connect first and second portions of the body vessel to permit blood flow therethrough. The sleeve member can be discrete to the coupled prosthesis or can have one end fixedly attached to the coupled prosthesis.11-15-2012
20100222867DRUG DELIVERY FROM STENTS - An intravascular stent has a coat comprising a crosslinked amphiphilic polymer and a sparingly water soluble matrix metalloproteinase inhibitor (MMPI). Preferably the polymer is formed from 2-methacryloyloxy-2′-ethyltrimethylammonium phosphate inner salt, C09-02-2010
20120290070Control Of Degradation Profile Of Bioabsorbable Poly(L-Lactide) Scaffold - Methods of controlling the degradation profile of a biodegradable stent scaffolding are disclosed. Disclosed methods include controlling features of the degradation profile including the time to loss of radial strength and the degradation time of the stent.11-15-2012
20120290073BIOABSORBABLE SCAFFOLDS MADE FROM COMPOSITES - Bioabsorbable scaffolds made at least in part of a poly(L-lactide)-based composite are disclosed. The composite includes poly(4-hydroxybutyrate) or poly(L-lactide)-b-polycaprolactone block copolymer, which increases the fracture toughness or fracture resistance of the scaffold. The composite can further include bioceramic particles, L-lactide monomer, or both dispersed throughout the composite. The bioceramic particles improve the radial strength and stiffness of the scaffold. The L-lactide monomer is used to control the absorption rate of the scaffold.11-15-2012
20120290071Bioabsorbable Scaffold With Particles Providing Delayed Acceleration of Degradation - Methods of controlling the degradation profile of a biodegradable stent scaffolding are disclosed. A bioabsorbable scaffold having a plurality of particles incorporated into the scaffolding that accelerate the absorption of the scaffolding after an induction time during degradation is disclosed.11-15-2012
20100198335Stent Coating For Eluting Medication - A vascular stent comprising a drug-eluting outer layer of a porous sputtered columnar metal having each column capped with a biocompatible carbon-containing material is described. This is done by placing the stent over a close-fitting mandrel and rotating the assembly in a sputter flux. The result is a coating that is evenly distributed over the outward-facing side of the stent's wire mesh while preventing the sputtered columnar coating from reaching the inward facing side where a smooth hemocompatible surface is required. The stent is then removed from the mandrel, exposing all surfaces, and finally coated with a layer of carbon such as amorphous carbon or diamond-like carbon. The carbonaceous coating enhances biocompatibility without preventing elutriation of a therapeutic drug provided in the porosity formed between the columnar structures. The result is a stent that is adapted to both the hemodynamic and the immune response requirements of its vascular environment.08-05-2010
20100198333PREFORM FOR AND AN ENDOLUMINAL PROSTHESIS - An endoluminal prosthesis may include a tubular graft extending in a longitudinal direction, where the graft has an inner surface forming a lumen extending a length of the graft. An elongate member may be attached to the graft in a circumferentially and longitudinally extending manner such that the elongate member forms a series of longitudinally spaced apart turns, each turn extending substantially around a circumference of the graft. The elongate member may torsion the graft in at least the circumferential direction and cause the graft to form circumferentially and longitudinally extending folds in the portions of the graft disposed between longitudinally adjacent turns of the elongate member.08-05-2010
20100198332IMPLANT WITH A BASE BODY OF A BIOCORRODIBLE MAGNESIUM ALLOY - An implant consisting entirely or in part of a biocorrodible magnesium alloy having the composition 08-05-2010
20100262226RADIALLY EXPANSIBLE STENT - There is disclosed herein a radially expansible stent formed from a tube, comprising a continuous spiral of tube material with a plurality of turns (10-14-2010
20130018452Anti-Migration Stent with Quill Filaments - A stent that includes a plurality of quill filaments. Each quill filament includes filament material, a surface, and a plurality of quills. Each quill has a tip, a body, and a base where the body extends from the base to the tip. The quill filaments can be interwoven to form the stent or the quill filaments can be engaged to the framework of a stent.01-17-2013
20110160842Clad Composite Stent - A body compatible stent is formed of multiple filaments arranged in at least two sets of oppositely directed helical windings interwoven with one another in a braided configuration. Each of the filaments is a composite including a central core and a case surrounding the core. In the more preferred version, the core is formed of a radiopaque and relatively ductile material, e.g. tantalum or platinum. The outer case is formed of a relatively resilient material, e.g. a cobalt/chromium based alloy. Favorable mechanical characteristics of the stent are determined by the case, while the core enables in vivo imaging of the stent. The composite filaments are formed by a drawn filled tubing process in which the core is inserted into a tubular case of a diameter substantially more than the intended final filament diameter. The composite filament is cold-worked in several steps to reduce its diameter, and annealed between successive cold working steps. After the final cold working step, the composite filament is formed into the desired shape and age hardened. Alternative composite filaments employ an intermediate barrier layer between the case and core, a biocompatible cover layer surrounding the case, and a radiopaque case surrounding a structural core.06-30-2011
20110160841MEDICAL APPLIANCE AND SURFACE TREATMENT METHOD THEREOF - A surface treatment method for a medical appliance is provided. The surface treatment method includes providing a metal layer; forming an intermediate layer on a surface of the metal layer, in which a thickness of the intermediate layer is greater than a thickness of a native oxide layer of the metal surface; and grafting a functional polymer on the intermediate layer through an electrodeposition process.06-30-2011
20110160840Repetitive Cell Bifurcation / Side Branch Ostia Support Stent - A stent comprises at least one closed pathway that defines a single cell. In some embodiments, the closed pathway includes a plurality of petals constructed and arranged to extend away from the tubular wall of the stent. In one embodiment, some of the petals of the closed pathway overlap other of the petals of the closed pathway when the stent is in a reduced state. In at least one embodiment, the stent comprises a plurality of closed pathways. In one embodiment, the closed pathways are arranged in bands that extend either along the length of the stent or about the circumference of the stent.06-30-2011
20080208313Drug Coated Stent With Magnesium Topcoat - A method for manufacturing a drug carrying stent includes applying at least a first therapeutic agent to at least an outer portion of a stent framework and applying a first magnesium coating on at least a first portion of the applied first therapeutic agent.08-28-2008
20130172981DEVICES AND METHODS FOR CONTROL OF BLOOD PRESSURE - Apparatus and methods are described including an implantable device having first and second longitudinal ends, the device having a length of less than 80 mm when the device is unconstrained. The device includes struts arranged such that, when the device is unconstrained, along a continuous portion of the device having a length that is at least 5 mm, a maximum inter-strut distance defined by any set of two adjacent struts is more than 1.5 times as great as a maximum inter-strut distance defined by any set of two adjacent struts within longitudinal portions of the device within 3 mm of the longitudinal ends of the device. Other applications are also described.07-04-2013
20130172982POLYMER STENT WITH BREAK-AWAY LINKS FOR ENHANCED STENT RETENTION - Polymer stents with break-away links and methods of forming the links for improved stent retention on an expandable member during delivery are disclosed.07-04-2013
20080249607Biocompatable Nanophase Materials - A metallic substance having a nanophase surface.10-09-2008
20080249606Methods for Determining the Effect of a Treatment on the Cross-Beta Structure Content of a Protein; Selection of Treatments and Uses Thereof - The invention relates to the field of biochemistry, biophysical chemistry, molecular biology, structural biology and medicine. More in particular, the invention relates to cross-β structure conformation. The invention provides a method for determining a difference in the cross-β structure content of a protein in a reference sample compared to said protein in a test sample wherein the test sample has been subjected to a treatment that is expected to have an effect on the cross-β structure content of said protein comprising—determining in said reference sample the cross-β structure content of said protein—subjecting said protein to a treatment that is expected to have an effect on the cross-β structure content to obtain said test sample—determining in said obtained test sample the cross-β structure content of said protein—determining whether the cross-β structure content of the reference sample is different from the cross-β structure content in the test sample.10-09-2008
20080249603APPARATUS AND METHOD FOR MEDICAL PROCEDURES WITHIN A SPINE - Devices and methods for performing a procedure within a spine are disclosed herein. In one embodiment, a method includes expanding an expandable member to move a tissue portion and form a cavity within an interior of a bone-related structure. At least a portion of the cavity is filled with a filler material while simultaneously withdrawing a medium from the expandable member at a predefined ratio such that the tissue portion substantially maintains its moved position. In some embodiments, the predefined ratio is 1:1. In another embodiment, a method includes expanding an expandable member to move a tissue portion and form a cavity within an interior of an intervertebral disc. At least a portion of the cavity is filled with a filler material while substantially maintaining the moved position of the tissue portion.10-09-2008
20080243227RADIOPAQUE MARKERS FOR IMPLANTABLE STENTS AND METHODS FOR MANUFACTURING THE SAME - Radiopaque markers for use with stents implantable within a body vessel are provided with one or more through-holes. Each through-hole extends through the thickness of the marker to expose a portion of the stent underlying the marker. The marker is welded to the stent through each through-hole. Also provided are stents incorporating a radiopaque marker having one or more through-holes suitable for receiving a weld. Methods are provided for securing a radiopaque marker having one or more through-holes to a stent.10-02-2008
20080243226IMPLANTABLE STENTS WITH RADIOPAQUE MARKERS AND METHODS FOR MANUFACTURING THE SAME - Stents implantable within a body vessel include a strut with a receiving surface. The receiving surface has two openings passing through this surface. A radiopaque marker has a first prong received at least in part by one of the openings and a second prong received at least in part by the other opening. Approaches and methods are provided for enhancing engagement of the marker to the strut to prevent unintentional removal or dissociation of the marker from the strut.10-02-2008
20090138070Stent Apparatuses for Treatment Via Body Lumens and Methods of Use - An enhanced stent apparatus, comprising: a support element, wherein the support element is constructed to be positioned in a body lumen; and, a porous structure, the porous structure located on a surface of the support element, and wherein the porous structure is comprised of at least one fiber under 30 microns in diameter, has a coverage area of less than 30% and is provided with apertures.05-28-2009
20110264193OPTIMAL RATIO OF POLAR AND BENDING MOMENT OF INERTIA FOR STENT STRUT DESIGN - An intravascular stent is provided to be implanted in coronary arteries and other body lumens. The transverse cross-section of at least some of the stent struts have a ratio of polar and bending moments of inertia, which results in optimal resistance to stent twisting. This resistance to twisting ratio for the stent struts minimizes out of plane twisting of the struts or projecting edges of the struts when the stent is expanded from a compressed diameter to an expanded diameter in a coronary artery.10-27-2011
20080221661Stent design with struts of various angles and stiffness - The present invention is directed to stent that has a plurality of axially spaced serpentine bands. Each serpentine band comprises a plurality of struts, wherein adjacent struts are connected to each other forming a plurality of peaks and valleys. The plurality of struts comprise a plurality of adjacent pairs of struts, wherein each adjacent pair of struts comprises a first strut and a second strut and wherein the first and second struts have a first end, a second end and a length and a plurality of interconnecting struts axially connect the serpentine bands. The stent further includes a plurality of connector nodes, wherein a plurality of first and second struts that are associated with a connector node have a greater stiffness than a plurality of struts that are not associated with a connector node.09-11-2008
20090287293MAGNETICALLY INDUCED RADIAL EXPANSION VASCULAR STENT - A magnetically induced radially expandable vascular stent for use inside a human body to hold open a stenosed vascular lumen. The stent comprises a flexible yet non elastic tubular main body, defining a peripheral wall having a radially outwardly expanded limit condition. A plurality of magnets are mounted in closely spaced wall pockets made in the main body peripheral wall. The relative orientation and position of the magnets are such that an equilibrium state is achieved corresponding to the tubular main body radially outward expanded condition, whereby the net effect of magnetic repulsion between the array of magnets is transformed into a synchronous mechanical radial expansion force of the stent tubular main body to an expanded stable condition thereof.11-19-2009
20130096667HEAT-TREATED TANTALUM-ALLOY PRODUCTS, IMPLANTABLE MEDICAL DEVICES INCORPORATING SAME, AND METHODS OF PROCESSING TANTALUM-ALLOY PRODUCTS - The present disclosure is directed to tantalum-alloy products, implantable medical devices that incorporate tantalum-alloy products such as stents or other implantable medical devices, methods of making and/or processing the tantalum-alloy products and implantable medical devices, and methods of using the implantable medical devices. In an embodiment, a stent includes a stent body having a plurality of struts. At least a portion of the stent body is made from a tantalum alloy. The tantalum alloy includes a tantalum content of about 77 weight % (“wt %”) to about 92 wt %, a niobium content of about 7 wt % to about 13 wt %, and a tungsten content of about 1 wt % to about 10 wt %. The tantalum alloy exhibits at least one mechanical property modified by heat treatment thereof, such as yield strength, ultimate tensile strength, or ductility.04-18-2013
20110270381METHODS AND APPARATUS FOR STENTING COMPRISING ENHANCED EMBOLIC PROTECTION COUPLED WITH IMPROVED PROTECTIONS AGAINST RESTENOSIS AND THROMBUS FORMATION - Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.11-03-2011
20110270379Mobile External Coupling for Branch Vessel Connection - An endovascular prosthesis includes a tubular body and a mobile external coupling. The tubular body includes a graft material and stents coupled thereto which forms a lumen therethrough. The mobile external coupling extends outwardly from the tubular body. The mobile external coupling includes a graft material and is generally frustoconically shaped. The mobile external coupling includes a base coupled to the tubular body, a top spaced from the tubular body, and a coupling lumen disposed between the base and the top, wherein the coupling lumen is in flow communication with the body lumen. A coupling deployment device is coupled to the coupling graft material to provide an extension force to extend the mobile external coupling from a collapsed configuration against the tubular body to an extended position wherein the mobile external coupling extends from the tubular body.11-03-2011
20130138202BLOOD PERFUSION DEVICE - A perfusion device and a delivery system for repair of a damaged portion of a body vessel. Perfusion device can include a tubular body that is self-expandable, having a proximal portion, a distal portion, and an intermediate portion. One or more series of barbs can be disposed circumferentially along the intermediate portion. Barbs are capable of penetrating into the tunica intima and tunica media of said vessel wall upon insertion of said device into said body vessel, and not into said tunica adventitia. A graft can be associated with the tubular body. Graft has a proximal end and a distal end, and preferably extends entirely along a luminal wall of the tubular body. Graft may also extend along an exterior surface of the tubular body at the proximal and distal portions. A remodelable covering can be applied along the intermediate portion. Delivery devices for the perfusion implant and methods of delivering the perfusion implant are also provided.05-30-2013
20130096668OPTIMAL RATIO OF POLAR AND BENDING MOMENT OF INERTIA FOR STENT STRUT DESIGN - An intravascular stent is provided to be implanted in coronary arteries and other body lumens. The transverse cross-section of at least some of the stent struts have a ratio of polar and bending moments of inertia, which results in optimal resistance to stent twisting. This resistance to twisting ratio for the stent struts minimizes out of plane twisting of the struts or projecting edges of the struts when the stent is expanded from a compressed diameter to an expanded diameter in a coronary artery.04-18-2013
20130123902MODULAR GRAFT COMPONENT JUNCTIONS - The present invention embodies an endovascular graft having an attachment frame connection mechanism that allows placement of the main body component in vasculature in combination with limb components. Various limb component-to-main body component attachment mechanisms are provided which ensure a reliable bond while facilitating a smaller delivery profile.05-16-2013
20130123901Stent with in situ determination of wall areas with differences in porosity - This invention gives physicians in situ control to create differences in wall porosity between different areas of a stent wall. This enables a physician to customize the stent within a blood vessel to selectively block blood flow to an aneurysm with a low-porosity area of the stent wall, but allow blood flow to nearby branching vessels through one or more high-porosity areas of the stent wall. The method comprises inserting a stent into a blood vessel and, in situ, expanding the stent in a non-uniform manner, thereby causing one or more areas of the stent wall to have a lower post-expansion porosity than the rest of the stent wall. With this invention, physicians can selectively block blood flow into an aneurysm while maintaining blood flow into nearby branching vessels, even in tortuous and complex vessel configurations.05-16-2013
20110313510Polymer Metal and Composite Implantable Medical Devices - A device and a method of manufacturing an implantable medical device, such as a stent, are described herein. The device includes a metallic region composed of a bioerodable metal and a polymer region composed of a biodegradable polymer contacting the metallic region. The metallic region may erode at a different rate when exposed to bodily fluids than the polymer region when exposed to bodily fluids. In certain embodiments, the polymer region is an outer layer and the metallic region is an inner layer of the device. A further aspect of the invention includes device and a method of manufacturing the device that includes a mixture of a biodegradable polymer and bioerodable metallic particles. The mixture may be used to fabricate an implantable medical device or to coat an implantable medical device. In some embodiments, the metallic particles are metallic nanoparticles.12-22-2011
20110313509STENT WITH COMPACT CRIMP CONFIGURATION - A stent having a compacted configuration in which adjacent crowns of its undulating rings overlap one another. The overlapping compacted configuration provides for a relatively low profile in view of the coverage that is achieved by the stent upon expansion.12-22-2011
20110313508ENDOVASCULAR PLATFORMS FOR UNIFORM THERAPEUTIC DELIVERY TO LOCAL TARGETS - An endovascular platform is provided that includes a periodic tiling-based stent structure having a parallelogram tile associated with a fundamental domain and an intrinsic cell-shape. A lattice vector includes a section of the parallelogram tile where the lattice vector is circumferentially folded to create helical repetition of cells.12-22-2011
20130131782BIOABSORBABLE POLYMERIC MEDICAL DEVICE - In embodiments there is described a cardiovascular tube-shaped lockable and expandable bioabsorbable scaffold having a low immunogenicity manufactured from a crystallizable bioabsorbable polymer composition or blend.05-23-2013
20130131781BIOCOMPOSITE MEDICAL CONSTRUCTS INCLUDING ARTIFICIAL TISSUES, VESSELS AND PATCHES - The disclosure describes methods of making collagen based biocomposite constructs and related devices. The methods include: (a) winding at least one collagen fiber a number of revolutions about a length of a support member having a long axis, the winding having at least one defined pitch and/or fiber angle relative to the long axis of the support member to form an elongate construct; and (b) applying a fluid polymeric material, such as, for example, an acrylate emulsion and/or other thermoplastic material, onto the collagen fiber during the winding step. Optionally, the fluid polymeric material can include antibiotics and/or other therapeutic agents for additional function/utility.05-23-2013
20110060399SURFACE STRUCTURE OF A COMPONENT OF A MEDICAL DEVICE AND A METHOD OF FORMING THE SURFACE STRUCTURE - A method of forming a surface structure of a component of a medical devices includes forming a fatigue-resistant portion, which entails forming a first layer comprising a transition metal selected from the group consisting of Ta, Nb, Mo, V, Mn, Fe, Cr, Co, Ni, Cu, and Si on at least a portion of a surface of the component, where the surface comprises a nickel-titanium alloy, and alloying the transition metal of the first layer with the nickel-titanium alloy of the surface. The method further includes forming a rough outer surface of the fatigue-resistant portion where the rough outer surface is adapted for adhesion of a material thereto.03-10-2011
20080200975Vascular Prosthesis with Anastomotic Member - A medical device for implantation in a vessel is disclosed. The medical device comprises at least one anastomotic member, at least partially interposing a non-woven liner of electrospun fibers and a non-woven cover of electrospun fibers. The at least one anastomotic member is designed for engaging at least one end of the medical device to a wall of the vessel upon implantation of the medical device within the vessel.08-21-2008
20100286759MEDICAL DEVICE SUITABLE FOR LOCATION IN A BODY LUMEN11-11-2010
20100286758Implantable Temporary Flow Restrictor Device - An implantable flow restrictor plug is disclosed that is disposed within a deployed endoluminal prosthesis to initially restrict, then gradually restore blood flow through the prosthesis after an angioplasty procedure. Upon initial deployment, the plug has a tubular biodegradable body defining a blood flow lumen therethrough that is sized to effectively reduce the amount of blood flow exiting the prosthesis. An inner surface of the body erodes or biodegrades in vivo to enlarge the plug lumen, thereby gradually restoring blood flow through the prosthesis until blood flow is unimpeded through the prosthesis, i.e., blood flow through the vessel is fully restored. The flow restrictor plug may be attached to the endoluminal prosthesis to be delivered and deployed therewith, or may be formed within a previously deployed prosthesis.11-11-2010
20130150947SCAFFOLD SYSTEM TO REPAIR CARDIOVASCULAR CONDITIONS - A device for treating a cardiovascular condition includes an expandable scaffold positionable in a portion of a vasculature of a mammal; and maintained via stent technology, wherein the scaffold is comprised of electrospun fibers composed of a biodegradable compound. The biodegradable compound serves as a temporary template that allows the cardiovascular tissue to be rebuilt about the scaffold.06-13-2013
20130150948Polymeric Stents and Method of Manufacturing Same - A pattern is used to form a stent scaffold from a polymeric precursor tube having a particular outer diameter. A new pattern can be derived from a base pattern, wherein the new pattern can be used to form a stent scaffold from a precursor tube having an outer diameter OD06-13-2013
20120277850Method of Making an Endoluminal Vascular Prosthesis - A flat sheet of woven material includes warp yarns and weft yarns interlaced at substantially right angles to each other. A graft material is cut from the flat sheet of woven material such that the graft material includes a graft material longitudinal axis and the warp yarns are disposed at an angle relative to the graft material longitudinal axis. The warp yarns and weft yarns are not parallel to or perpendicular to the graft material longitudinal axis. The graft material is formed into the shape of an endoluminal prosthesis, such as by rolling opposing edges towards each other and securing the opposing edges to each other. The endoluminal prosthesis thus includes warp yarns disposed at an angle relative to the prosthesis longitudinal axis.11-01-2012
20130150949TUBE WITH REVERSE NECKING PROPERTIES - An improved tubular structure adapted to increase in diameter upon application of axial force is provided. Increase in diameter is achieved by constructing the tube from multiple layers of material that move relative to each other during axial elongation of the tube. The tube of the present invention can be used both to avoid problems in “necking” found in many prior tube devices, and to provide additional benefits that increases in diameter of the tube during axial elongation can provide. As such, the tube of the present invention may be useful as a manufacturing aid, as a deployment sheath (for example, to deliver medical devices), and in other applications that may benefit from easier tubular sheath removal.06-13-2013
20100318179DEVICES, SYSTEMS, AND METHODS FOR REPAIR OF VASCULAR DEFECTS - A balloon-expandable shunt is disclosed for shunting a vessel which has a graft with two ends and is coupled with or to at least one expandable support element at or near at least one of its ends. The shunt is bifurcated at an aperture that leads to a side-channel and which has a closed configuration and an open configuration such that when the aperture is in the closed configuration it defines a clot-resistant inner graft surface and when the aperture is in the open configuration it is configured to provide access to the shunt for a balloon that actuates the expandable support element. A balloon configured for actuating the shunt is also disclosed. A kit is also disclosed, which has a bifurcated graft that has at least one expandable support element and a balloon for actuating the at least one expandable support element.12-16-2010
20100318178METHOD AND APPARATUS FOR ALLOWING BLOOD FLOW THROUGH AN OCCLUDED VESSEL - A device arranged to sustain and/or provide at least partial patency of a small blood vessel exhibiting an occlusion, the device constituted of a tubular body expandable from a first small diameter state for manipulation to, and through, the occlusion of the small blood vessel and a second large diameter state, the inner dimensions of the second large diameter state being no more than 50% of the diameter of the small blood vessel at the occlusion location, the device presenting a conduit for blood flow through the occlusion when in the large diameter state. In one embodiment the small blood vessel is an intracranial blood vessel.12-16-2010
20110282432Vascular Graft With Lateral Opening - A vascular graft includes a flexible conduit including a sidewall defining a cavity extending between a first end and a second end. The first end includes an opening that is oriented substantially perpendicular to a centerline axis of the conduit. The second end includes a end wall and a tapered portion extending from the sidewall to the end wall such that the cavity includes a first diameter defined at the first end and a second diameter defined at the second end that is smaller than the first diameter. A lateral opening extends through the sidewall and is oriented substantially parallel to the centerline axis. The lateral opening positioned near the second end and is sized to provide flow communication between the cavity and a blood vessel.11-17-2011
20110288630ENDOPROSTHESIS CONTAINING MULTI-PHASE FERROUS STELL - An endoprosthesis fabricated from multi-phase ferrous steel. Endoprostheses can include a variety of devices such as staples, orthodontic wires, heart valves, filter devices, and stents, many of which devices are diametrically expandable devices. Multi-phase ferrous steels include dual phase steels and transformation induced plasticity steels (TRIP steels).11-24-2011
20120029617STENTS FOR BLOOD VESSELS - A stent for supporting part of a blood vessel includes a supporting portion around which or within which a part of an intact blood vessel other than a graft can be placed. The stent internally or externally supports that part of the blood vessel. The supporting portion of the stent is of a shape and/or orientation whereby flow within the vessel is caused to follow a non-planar curve. By maintaining a non-planar curvature in the vessel itself, favorable blood flow velocity patterns can be achieved through the generation therein of “swirl” flow. Failures in such vessels through diseases, such as thrombosis, atherosclerosis, intimal hyperplasia or through blockage, kinking or collaps, can be significantly reduced.02-02-2012
20120029616Stent Support Devices - Various embodiments of methods and devices for coating stents are described herein.02-02-2012
20120029615BIOABSORBABLE STENT WTIH LAYERS HAVING DIFFERENT DEGRADATION RATES - A bioabsorbable stent and method of forming the same including a stent scaffolding formed from polymer layers with different degradation rates is disclosed. The polymer layers include an abluminal layer, a luminal layer, and optionally one or more middle layers. A degradation rate of the layers increases from the luminal layer to the abluminal layer.02-02-2012
20120029614Stent-Graft with Bioabsorbable Structural Support - The invention relates to a stent-graft with a bioabsorbable structure and a permanent graft for luminal support and ‘treatment of arterial fistulas, occlusive disease, and aneurysms. The bioabsorbable structure is formed from braided filaments of materials such as PLA, PLLA, PDLA, and PGA and the graft is formed from materials such as PET, ePTFE, PCU or PU.02-02-2012
20120029612COVERED TOROID STENT AND METHODS OF MANUFACTURE - An expandable stent for implantation in a body lumen, such as coronary-artery, and methods for manufacturing such a stent are provided, whereby the stent comprises at least one radially expandable cylindrical crown covered with a polymeric tube. The at least one crown is generally aligned on a longitudinal axis of the stent and connected to at least one further stent segment with highly flexible connectors formed from the same or different polymeric material as the crown covering material. In a preferred embodiment the cylindrical crown is loaded or coated with a therapeutic active agent.02-02-2012
20130197622Means for Controlled Sealing of Endovascular Devices - Expandable sealing means for endoluminal devices have been developed for controlled activation. The devices have the benefits of a low profile mechanism (for both self-expanding and balloon-expanding prostheses), contained, not open, release of the material, active conformation to the “leak sites” such that leakage areas are filled without disrupting the physical and functional integrity of the prosthesis, and on-demand, controlled activation, that may not be pressure activated.08-01-2013
20120296415BIOABSORBABLE STENT - A bioabsorbable stent has a relatively high radial force and can be placed directly at the lesion without the possibility or reducing the possibility of occluding the lesion again after placement. The bioabsorbable stent is formed from a mixture composed of a bioabsorbable aliphatic polyester and an aromatic compound having one or more aromatic rings.11-22-2012
20130204348LONGITUDINALLY FLEXIBLE EXPANDABLE STENT - Segmented articulatable stent of open structure comprised of end-connected struts of first and second lengths making up first and second segments with angular interconnects between adjacent first and second segments.08-08-2013
20120065723Intravascular hinge stent - A balloon or self expandable endoprosthesis formed of a single or multiple joined stent sections. Each section has a node and strut structure extending throughout in order to uncouple expansion forces of the stent to hold a blood vessel outward from crush forces that resist the formation of an oval shape during crush deformation. The hinge can bend in the direction of a uniformly curved surface of the stent but not in the radial direction. The strut can bend in the radial direction but not in the uniformly curved surface of the stent. The widths, lengths, and radial dimensions of the hinges and struts provide a balloon-expandable hinge stent that is non-crushable. For a self-expanding stent the hinge and strut dimensions provide expansion forces that are controlled independently from crush forces. Expansion properties are determined by the hinge dimensions and crush properties are determined independently by strut dimensions.03-15-2012
20130096666IMPLANTABLE MEDICAL DEVICES INCLUDING A HEAT-TREATED TANTALUM-ALLOY BODY HAVING A DRUG-ELUTING COATING THEREON, AND METHODS OF MAKING AND USING SAME - The present disclosure is directed to a drug-eluting implantable medical devices that includes a tantalum-alloy body having a drug-eluting coating thereon for delivering a drug to treat, for example, restenosis. In an embodiment, an implantable medical device includes a body sized and configured to be implanted in a living subject. At least a portion of the body may comprise a tantalum alloy. The tantalum alloy includes a tantalum content of about 77 weight % (“wt %”) to about 92 wt %, a niobium content of about 7 wt % to about 13 wt %, and a tungsten content of about 1 wt % to about 10 wt %. The tantalum alloy exhibits at least one mechanical property modified by heat treatment thereof. The body has a drug-eluting coating thereon.04-18-2013
20120083871SOFT CROWNS - Soft crowns are provided for use in a medical device. Soft crowns may reduce the incidence of tissue perforations as a medical device engages a luminal wall. In certain embodiments, a soft crown may include a first strut and a second strut interconnected by an end portion. The end portion may include a third strut and a fourth strut that intersect to form a distal end of the soft crown. The first strut and the second strut may intersect other struts in the medical device to attach the crown thereto. The soft crown may bend or pivot about a plane defined by the intersections of the first strut and the second strut to the medical device.04-05-2012
20130211496KNITTED STENT - The subject-matter of the invention relates to a knitted tube (08-15-2013
20130211497MEDICAL PROSTHESES HAVING BUNDLED AND NON-BUNDLED REGIONS - The present embodiments provide an endoluminal prosthesis, such as a stent-graft, having a relatively low delivery profile. In one embodiment, the prosthesis comprises a membrane, and at least one stent having contracted and expanded states, where the stent is coupled to the membrane and maintains patency in the expanded state. The prosthesis further may comprise selectively oriented axial and/or circumferential fibers arranged at predetermined locations along the length and circumference of the prosthesis. An increased population density of the circumferential and/or axial fibers may be provided in areas in which the at least one stent portion is attached to the membrane, or in areas of higher physiological loads imposed upon the endoluminal prosthesis. Selectively orienting axial fibers and circumferential fibers at predetermined locations along the length and circumference of the prosthesis, but not continuously along the entire prosthesis, significantly reduces delivery profile due to the reduction in graft material.08-15-2013

Patent applications in class Stent structure

Patent applications in all subclasses Stent structure