Class / Patent application number | Description | Number of patent applications / Date published |
607120000 | With drug or medicament-dispensing | 26 |
20080234792 | SYSTEMS AND METHODS FOR TRANSVENOUS LEAD IMPLANTATION - Some embodiments relate to a method of implanting a cardiac lead. An expansion module is implanted in a target region within vasculature, the target region being defined by a portion of a brachiocephalic vein and a portion of a corresponding subclavian vein. The expansion module is transitioned from a collapsed state to an expanded state within the target region to contact the vasculature. A cardiac lead is implanted through the expansion module, the cardiac lead defining an intermediate section corresponding to the target region. The intermediate section of the cardiac lead includes a surface treatment adapted to reduce at least one of cell proliferation, thrombosis, fibrosis, and inflammation at the target region. | 09-25-2008 |
20090024197 | ELUTION CONTROL VIA GEOMETRIC FEATURES OF AN IMPLANTABLE SUBSTANCE MATRIX - A cardiac lead that is adapted and configured to elute a therapeutic agent to treat the surrounding tissue at a target location within a patient's heart is described. The cardiac lead includes a drug eluting member having a predetermined number of macroscopic surface features formed on its exterior surface. The macroscopic surface features allow the elution rate to be controlled and/or increased without the need for modifying the amount of therapeutic agent in the drug eluting member. | 01-22-2009 |
20090105794 | MICROPROCESSOR CONTROLLED DELIVERY SYSTEM FOR CARDIAC VALVE PROSTHESIS - An instrument for deploying a cardiac valve prosthesis, including a plurality of radially expandable portions, at an implantation site, includes a plurality of deployment elements each independently operable to obtain the radial expansion of a radially expandable portion of the valve prosthesis. The instrument includes a microprocessor configured to processes signals from one or more sensors and to optimize deployment of the valve prosthesis. | 04-23-2009 |
20090281606 | STEROID ELUTING PACING TIP ELECTRODE - An implantable cardioverter defibrillator (ICD) including a set of leads having electrodes disposed therein. The electrodes may include a weld electrode connected to an internal wire of the lead and the ICD and a tip electrode. The tip electrode may have a set of grooves or cut out regions in its outer surface to provide edge effects for currents applied through the tip electrode. The grooves or cut out regions may form gaps in the surface of the tip electrode exposing a medical compound that is housed within the tip electrode. The medical compound may elute through the gaps. | 11-12-2009 |
20100042195 | IMPLANTABLE LEAD WITH FLEXIBLE TIP FEATURES - A medical electrical lead comprises a flexible, elongate lead body extending along a longitudinal axis and having a proximal end and a distal end. A protective distal tip structure is disposed on the distal end of the lead body. The tip structure includes a plurality of compliant projections each extending distally from the distal end of the body in the direction of the longitudinal axis. The projections are configured to contact and bear against cardiac tissue when the lead is implanted, and are deformable under the action of an axially or radially directed force. The projections optionally include a coating over a substrate. The coating can include a hydrogel material and/or a pharmaceutical agent such as a steroid for reducing inflammation at the implantation site. | 02-18-2010 |
20100114284 | IMPLANTABLE LINE - An implantable line for implantation in the left ventricle or left atrium of the heart with perforation of the atrial or ventricular septum, having an elongated flexible line body and an electrode and/or a sensor and/or a medication-dispensing device in a distal segment of the line body, i.e., in the left atrium or the left ventricle in the use state of the, such that the part of the line body situated in the blood vessel in or on the heart in the use state is at least partially provided with a surface coating or a surface structure that promotes ingrowth with endogenous tissue. | 05-06-2010 |
20100125320 | OVERMOLDED COMPONENTS FOR IMPLANTABLE MEDICAL LEADS AND RELATED METHODS - The various embodiments disclosed herein relate to medical electrical leads. More specifically, certain embodiments relate to leads having one or more drug-eluting components that are overmolded or otherwise positioned on the lead. Other embodiments relate to leads having one or more patterned surfaces, including some leads with one or more patterned surfaces over which one or more drug-eluting components are positioned. Further implementations relate to leads having one or more overmolded patterned surfaces, including some embodiments in which the overmolded surfaces contain at least one drug-eluting component. | 05-20-2010 |
20110087317 | CONDUCTIVE POLYMERIC COATING WITH OPTIONAL BIOBENEFICIAL TOPCOAT FOR A MEDICAL LEAD - A cardiac lead comprising a lead body extending from a proximal end portion to a distal end portion; a cardiac electrode disposed along the lead body; and a coating associated with at least a portion of the electrode, wherein the coating comprises a conductive polymer. | 04-14-2011 |
20110098797 | DRUG ELUTING COMPOSITE - The present invention relates to materials having therapeutic compositions releasably contained within the materials. The materials are configured to release therapeutic compositions at a desired rate. The present invention also relates to devices incorporating the materials. | 04-28-2011 |
20110112618 | DRUG ELUTING COMPOSITE - The present invention relates to materials having therapeutic compositions releasably contained within the materials. The materials are configured to release therapeutic compositions at a desired rate. The present invention also relates to devices incorporating the materials. | 05-12-2011 |
20110125241 | LEAD INCLUDING COMPOSITE DEVICE FOR ELUTING A STEROID AND AN ANTIMICROBIAL - A lead may include a lead body including a proximal end and a distal end, an electrode proximate to the distal end of the lead body, and a monolithic controlled release device located proximate to the electrode. According to this aspect of the disclosure, the monolithic controlled release device includes a polymer, a steroid mixed in the polymer, and an antimicrobial mixed in the polymer. | 05-26-2011 |
20110160831 | TAPERED DRUG-ELUTING COLLAR FOR A MEDICAL ELECTRICAL LEAD - A medical electrical lead includes a tapered distal tip having a tapered drug-eluting component incorporated therein. The drug-eluting component can be an overmolded drug-eluting collar or a pre-molded drug eluting collar. The drug-eluting collar is disposed in a recess formed in the tapered distal tip and maintains the overall tapered profile of the distal tip. | 06-30-2011 |
20110218604 | Cardiac Lead for Epicardial, Endocardial and Trans-Coronary Sinus Placement - A cardiac lead includes a half-domed or semi-spherical shaped distal assembly and an active fixation mechanism. The half-domed or semi-spherical shape provides directionality as to whether a flat side of the lead is facing the myocardial tissue and therefore the active fixation mechanism can be deployed safely into the myocardial tissue. | 09-08-2011 |
20120046724 | IMPLANTABLE CARDIAC STIMULATION DRUG RELEASING ELECTRODE - In an implantable cardiac stimulation electrode, an implantable cardiac stimulation lead, and a stimulation delivery method, the electrode body is provided with a matrix metalloproteinase inhibitor or a precursor thereof, in a release structure that allows release of the metalloproteinase inhibitor or precursor thereof from the electrode body into surrounding tissue, after implantation. | 02-23-2012 |
20120165913 | MEDICAL ELECTRICAL LEAD HAVING BIOLOGICAL SURFACE AND METHODS OF MAKING AND USING SAME - An implantable electrical lead suitable for left sided cardiac placement, the implantable medical electrical lead having an external blood contacting surface having an external coating including a monolayer of at least one biological agent that promotes endothelialization covalently attached to a polymeric lead surface. | 06-28-2012 |
20120165914 | EXTENDABLE/RETRACTABLE FIXATION LEAD WITH DISTAL TRAVELLING SEAL AND RELATED DEVICES - An implantable lead having a distal assembly including a coupler, a fixation helix secured to the coupler, a housing in which the fixation helix and the coupler are disposed, and a resilient seal that is fixedly secured to the coupler between proximal and distal ends thereof and able to translate with the coupler relative to the housing. The seal is positioned to sealingly engage an internal surface of the housing. When the coupler is translated such that the fixation helix is in a fully extended position, the seal is positioned to substantially seal off the housing to prevent tissue ingrowth. | 06-28-2012 |
20130331920 | IMPLANTABLE INDIFFERENT REFERENCE ELECTRODE POLE - An implantable electrode device designed for heart stimulation and/or cardioversion/defibrillation in connection with a pacemaker or a defibrillator. The electrode device comprises a large-surface area indifferent reference electrode pole permanently implanted in the atrial septum and in electrical communication with a pacemaker or defibrillator. The electrode pole is made from biocompatible metal braiding and has a tube like opening. The electrical communication is positioned from the pacemaker/defibrillator via the right atrium of the heart through the indifferent electrode pole into the left atrium via the opening. Thus allowing electrical pulses to be delivered to the electrode pole and stimulating the heart. | 12-12-2013 |
20140031912 | Anchorage Devices Comprising an Active Pharmaceutical Ingredient - An anchorage device comprising a mesh substrate coupled to an implantable medical device is disclosed, where the mesh substrate has a coating comprising a polymer, and the mesh further comprises at least one active pharmaceutical ingredient. The active pharmaceutical agent is designed to elute from the mesh over time. The mesh substrate can be configured to reduce the mass of the anchorage device such that tissue in-growth and/or scar tissue formation at the treatment site is reduced. In some embodiments, the mesh substrate can be formed with a mesh having a low areal density. In some embodiments, the mesh substrate can include one or more apertures or pores to reduce the mass of the substrate. | 01-30-2014 |
20140155975 | CARDIAC RHYTHM MANAGEMENT SYSTEM WITH INTRAMURAL MYOCARDIAL PACING LEADS AND ELECTRODES - Medical devices and therapeutic methods for use in the field of cardiology, cardiac rhythm management and interventional cardiology, and more specifically to catheter-based systems for implantation of pacing leads and electrodes, or intramural myocardial reinforcement devices, within the myocardial wall of the heart, such as the ventricles, to provide improved cardiac function. | 06-05-2014 |
20140243946 | IMPLANTABLE MEDICAL DEVICE INCLUDING ASSEMBLY INCORPORATING RADIOPAQUE AGENT AND ELUTABLE DRUG INTO A POLYMERIC LEAD TIP - An assembly for an implantable device can be made from PEEK and can incorporate one or more radiopaque agents and one or more elutable drug components into a polymeric lead tip. The assembly can be machined or injection molded and can be configured, for example, as a housing for an active fixation lead or as an electrode base supporting a foil electrode. | 08-28-2014 |
20150306381 | LEADLESS CARDIAC PACEMAKER WITH RETRIEVAL FEATURES - An implantable leadless cardiac pacing device and associated retrieval features. The implantable device includes a docking member extending from the proximal end of the housing of the implantable device including a covering surrounding at least a portion of the docking member configured to facilitate retrieval of the implantable leadless cardiac pacing device. | 10-29-2015 |
20150374976 | IMPLANTABLE CAPSULE FOR LEADLESS CARDIAC PACING - The invention relates to an implantable capsule, particularly an autonomous capsule of cardiac stimulation, comprising a tubular body provided at the distal end of an anchoring element with a helical screw adapted to penetrate tissue a wall of an organ of a patient, the body housing a set of functional elements of the capsule. It comprises an annular support integral with the body and coaxial therewith, said support surrounding the base of the anchoring element and comprising a series of openings radially extending. The base of the anchoring element comprises a series of rods or tubes projecting in a generally radial direction, and engaged in said openings to thereby secure the anchoring element to the support. | 12-31-2015 |
20160008594 | IMPLANTABLE CAPSULE FOR LEADLESS CARDIAC PACING | 01-14-2016 |
20160067478 | RECEPTACLE FOR PACEMAKER LEAD - A lead receptacle having a lumen configured to traverse from an outer side of an outermost intercostal muscle to an inner side of an innermost intercostal muscle of an intercostal space of a patient and to support a lead traversing through the lumen. The lumen being configured to support one or more cardiac leads traversing through the intercostal space. | 03-10-2016 |
20160184582 | IMPLANTABLE MEDICAL DEVICE INCLUDING ASSEMBLY INCORPORATING RADIOPAQUE AGENT AND ELUTABLE DRUG INTO A POLYMERIC LEAD TIP - An assembly for an implantable device can be made from PEEK and can incorporate one or more radiopaque agents and one or more elutable drug components into a polymeric lead tip. The assembly can be machined or injection molded and can be configured, for example, as a housing for an active fixation lead or as an electrode base supporting a foil electrode. | 06-30-2016 |
20180021572 | RECEPTACLE FOR PACEMAKER LEAD | 01-25-2018 |