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Combined with nonelectrical therapy

Subclass of:

607 - Surgery: light, thermal, and electrical application

607001000 - LIGHT, THERMAL, AND ELECTRICAL APPLICATION

607002000 - Electrical therapeutic systems

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DocumentTitleDate
20090210018Method for treating neurological /psychiatric disorders with stimulation to the subcaudate area of the brain - A method for treating a patient with a neurological or psychiatric disorder, comprising applying stimulation to at least a portion of the patient's subcaudate white matter of the subcaudate area under conditions effective to provide the patient with at least a partial relief from the neurological or psychiatric disorder. The stimulation may be electrical and/or pharmacological.08-20-2009
20110208258METHOD FOR CAPTURING THE CHANGES INDUCED IN AN INITIAL CRYSTAL STRUCTURE BY THE ACTION OF THE ACOUSTIC AND ELECTROMAGNETIC FIELDS OF A BIOLOGICAL MEDIUM AND A DEVICE FOR CARRYING OUT SAID METHOD, METHOD FOR DUPLICATING THE CHANGES IN THE INITIAL CRYSTAL STRUCTURE IN THE STRUCTURE OF A DUPLICATE CRYSTAL (VARIANTS) AND A DEVICE FOR CARRYING OUT SAID METHOD (VARIANTS), METHOD FOR EXERTING AN EFFECT ON A BIOLOGICAL OBJECT (VARIANTS) AND A DEVICE FOR CARRYING OUT SAID METHOD - The invention relates to medicinal equipment and is useful in physiotherapy for controlling the functions of biological objects.08-25-2011
20090005824ELECTROTRANSPORT DEVICES, METHODS AND DRUG ELECTRODE ASSEMBLIES - A drug electrode assembly usefully employed in an electrotransport device for the delivery of drugs across a tissue surface includes an electrode, a drug reservoir which stores the drug (including an ionized (e.g., anionic) or neutrally charged drug species), and a liquid impermeable solid-state assist ion conducting barrier layer interposed between the electrode and the drug reservoir. The barrier layer can be a single-ion conductor of a specific (unique) species of ion called the assist ion. During drug delivery, the assist ion moves across the barrier layer into or out of the drug reservoir, and as the assist ion crosses the barrier layer/drug reservoir interphase, the drug species moves to the tissue surface. The assist ion can be, for example, sodium ions (Na01-01-2009
20100057150METHODS AND APPARATUS FOR PULSED ELECTRIC FIELD NEUROMODULATION VIA AN INTRA-TO-EXTRAVASCULAR APPROACH - Methods and apparatus are provided for pulsed electric field neuromodulation via an intra-to-extravascular approach, e.g., to effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, changes in cytokine upregulation and other conditions in target neural fibers. In some embodiments, the ITEV PEF system comprises an intravascular catheter having one or more electrodes configured for intra-to-extravascular placement across a wall of patient's vessel into proximity with target neural fibers. With the electrode(s) passing from an intravascular position to an extravascular position prior to delivery of the PEF, a magnitude of applied voltage or energy delivered via the electrode(s) and necessary to achieve desired neuromodulation may be reduced relative to an intravascular PEF system having one or more electrodes positioned solely intravascularly. The methods and apparatus of the present invention may, for example, be used to modulate one or more target neural fibers that contribute to renal function.03-04-2010
20130085537APPARATUS AND METHODS FOR IMPLANT COUPLING INDICATION - A device is disclosed that includes an external unit configured to communicate with an implant unit beneath the skin of a subject and an indicator associated with the external unit. The indicator is configured to produce an indicator signal when the external unit is within a predetermined range of the implant unit. In addition, the indicator may be configured to vary the indicator signal according to a distance between the external unit and the implant unit. Furthermore, a method of locating an external unit with respect to an implant unit is disclosed that includes detecting a distance between the external unit and the implanted unit located beneath the skin of a subject, producing an indicator signal when the external unit is within a predetermined range of the implant unit, and varying the indicator signal as a function of a distance between the external unit and the implant unit.04-04-2013
20100010550BRANCHING THERAPY ELEMENTS AND METHOD OF THEIR INSERTION INTO LIVING TISSUE - An implantable medical system for electrical recording and or providing therapy to a plurality of tissue sites without damage to surrounding blood vessels is disclosed comprising: an implant body having a plurality of therapy elements, the elements being hingedly attached at one end to the surface of the body and releasably extendable outward from the surface of the body at the other end; a release mechanism for each of the elements; and a coating material covering the body and the elements; wherein upon dissolution of the coating material after implantation, the release mechanism is capable of causing the elements to extend outward at one end from the surface of the body and into a plurality of tissue sites without damage to the surrounding blood vessels. The method of implanting the system into a body is also disclosed.01-14-2010
20090192556SLEEP STAGE DETECTION - Therapy delivery to a patient may be controlled based on a determined sleep stage of the patient. In examples, the sleep stage may be determined based on a frequency characteristic of a biosignal indicative of brain activity of the patient. A frequency characteristic may include, for example, a power level within one or more frequency bands of the biosignal, a ratio of the power level in two or more frequency bands, or a pattern in the power level of one or more frequency bands over time. A therapy program may be selected or modified based on the sleep stage determination. Therapy may be delivered during the sleep stage according to the selected or modified therapy program. In some examples, therapy delivery may be controlled after making separate determinations of a sleep stage based on the biosignal and another physiological parameter, and confirming that the sleep stage determinations are consistent.07-30-2009
20090192558METHODS AND SYSTEMS OF TREATING PANCREATITIS PAIN - Methods and systems of treating a patient with pancreatitis pain include providing a stimulator, configuring one or more stimulation parameters to treat pancreatitis pain, programming the stimulator with the one or more stimulation parameters, generating a stimulus configured to treat pancreatitis pain with the stimulator in accordance with the one or more stimulation parameters, and applying the stimulus with the stimulator to one or more stimulation sites in accordance with the one or more stimulation parameters.07-30-2009
20090192557METHODS AND SYSTEMS OF TREATING PANCREATITIS PAIN CAUSED BY SPHINCTER OF ODDI DYSFUNCTION - Methods and systems of treating a patient with pancreatitis pain include providing a stimulator, configuring one or more stimulation parameters to control sphincter of Oddi function, programming the stimulator with the one or more stimulation parameters, generating a stimulus configured to control sphincter of Oddi function with the stimulator in accordance with the one or more stimulation parameters, and applying the stimulus with the stimulator to one or more stimulation sites in accordance with the one or more stimulation parameters.07-30-2009
20110196437Electroimmunization chamber - An electroimmunization chamber consists of a horizontal space designed for treatment of patients with HIV, who place themselves in supine lying position, and the upper part of which has a cover with adjustable height with a magnetic pulse generator. The patient rest area also contains fixed electrodes in the lower part and variable electrodes in the upper patient area, which generate electrical impulses that supplement the magnetic pulses. The mechanisms for control and regulation of the chamber ensure dosing of electro-magnetic energy that acts on the ionic channels of the GP120 protein that is present in HIV. These channels open and lose the necessary energy used for interacting with the CD4 receptors, which are marking molecules on the cell surface, which recognize certain antibodies.08-11-2011
20110196436Electrical Treatment Apparatus - A treatment method and apparatus for performing a diagnostic or therapeutic treatment. The apparatus comprises a treatment head for applying a diagnostic or therapeutic treatment to the body of a patient; means for delivering the treatment through the treatment head; a processor for controlling the treatment; an input arrangement operable by a practitioner to activate the delivery means for initiating the treatment; a sound generator operable at any time before and during the treatment by operation of the or a further input arrangement by the practitioner to generate pleasing sounds; and a speaker for supplying the sounds as output during treatment to distract and hold the attention of the patient.08-11-2011
20090248097INHIBITION OF INFLAMMATORY CYTOKINE PRODUCTION BY CHOLINERGIC AGONISTS AND VAGUS NERVE STIMULATION - A method of inhibiting the release of a proinflammatory cytokine in a cell is disclosed. The method comprises treating the cell with a cholinergic agonist. The method is useful in patients at risk for, or suffering from, a condition mediated by an inflammatory cytokine cascade, for example endotoxic shock. The cholinergic agonist treatment can be effected by stimulation of an efferent vagus nerve fiber, or the entire vagus nerve.10-01-2009
20100114193METHOD OF TREATING DEPRESSION, MOOD DISORDERS AND ANXIETY DISORDERS USING NEUROMODULATION - The present application involves a method and a system for using electrical stimulation and/or chemical stimulation to treat depression. More particularly, the method comprises surgically implanting an electrical stimulation lead and/or catheter that is in communication with a predetermined site which is coupled to a signal generator and/or infusion pump that release either an electrical signal and/or a pharmaceutical resulting in stimulation of the predetermined site thereby treating the mood and/or anxiety.05-06-2010
20100114191TREATMENT OF HEADACHE - Headache treatment methods are described and include providing an energy delivery device; locating a secondary or higher-order branch of a postganglionic nerve that provides innervation for a patient's head, by identifying a target region of the patient's head that includes the nerve branch; positioning, within the target region, a portion of the energy delivery device; and applying, from the positioned portion of the energy delivery device to the target region, an amount of energy effective to result in a stimulation activity of the nerve branch; and, after observing the stimulated nerve branch activity, delivering, from the energy delivery device to the nerve branch, energy in an amount effective to reduce a headache severity in the patient.05-06-2010
20130079835USE OF PULSED RADIO FREQUENCY - The invention relates to a method for medical treatment of a mammal, preferably a human, by applying pulsed radiofrequency (PRF) stimulation intravascularly. More particularly, said method has as effect that it boosts the immune system and/or that it relieves pain. In a preferred embodiment, the disease or condition to be treated is caused or accompanied by immunodeficiency, more preferably the disease or condition is selected from the group of cancer, infectious diseases, immunosuppression or otherwise caused immunodeficiencies. Also auto- immune diseases and conditions associated with allostatic load are preferred for treatment with the method of the invention. In an also preferred embodiment, the PRF stimulation is applied together with vaccination.03-28-2013
20130035734METHOD FOR TREATING NEUROPATHIC PAIN - Provided is a method for treating neuropathic pain, including: providing, to a patient suffering from said neuropathic pain, a visual illusion to correct a mismatch between motor commands and sensory feedback; and applying a cranial stimulation to said patient during at least part of the duration of said visual illusion. This is particularly applicable to the treating of neuropathic pain in patients suffering from spinal cord injuries.02-07-2013
20130079834MODULATION OF SIRTUINS BY VAGUS NERVE STIMULATION - Systems, devices and methods for modulation of sirtuins by neurostimulation. In particular, sirtuins may be modulated by stimulation of the vagus nerve. Further described herein generally are methods, systems and devices, for specifically modulating sirtuins, including sub-sets (types or localized regions) of sirtuins by vagus nerve stimulation (VNS).03-28-2013
20130041418METHODS FOR TREATING PULMONARY HYPERTENSION AND COMPOSITIONS COMPRISING VASOACTIVE INTESTINAL PEPTIDE - A method and device for discharging an electrical defibrillation pulse or an electrical demand pacer pulse or delivering at least one pharmaceutical agent to treat conditions such as cardiac arrest, bradycardia, arrhythmia, cardiac standstill, PEA, EMD and other heart conditions are disclosed. The pharmaceutical agent can be delivered into the heart tissue, the heart cavity, or the peritoneal cavity. The pharmaceutical agent can also include analgesics such as morphine. Also included are pharmaceutical agents used to increase myocardial contractility or inhibit platelet aggregation and vasoactive intestinal polypeptide (VIP) and thyroid hormones such as T3 and T4 can be delivered. A method for the treatment of cardiac arrest or pulmonary hypertension patients by administering a therapeutically effective amount of vasoactive intestinal polypeptide is also encompassed by the invention.02-14-2013
20100106207DYNAMIC NERVE STIMULATION IN COMBINATION WITH OTHER EATING DISORDER TREATMENT MODALITIES - A method for treatment of obesity or other disorders by electrical activation or inhibition of nerves is disclosed. This activation or inhibition can be accomplished by stimulating a nerve using an electrode. The method further comprises performing a surgical procedure and/or administering a weight loss drug.04-29-2010
20130041419Methods, Systems, and Devices for Pairing Vagus Nerve Stimulation with Motor Therapy in Stroke Patients - A method of treating motor deficits in a stroke patient, comprising assessing a patient's motor deficits, determining therapeutic goals for the patient, based on the patient's motor deficits, selecting therapeutic tasks based on the therapeutic goals, performing each of the selected therapeutic tasks repetitively, observing the performance of the therapeutic tasks, initiating the stimulation of the vagus nerve manually at approximately a predetermined moment during the performance of the therapeutic tasks, stimulating the vagus nerve of the patient during the performance of the selected therapeutic tasks, and improving the patient's motor deficits.02-14-2013
20120185004ANCHORAGE DEVICES COMPRISING AN ACTIVE PHARMACEUTICAL INGREDIENT - An anchorage device comprising a mesh substrate coupled to an implantable medical device is disclosed, where the mesh substrate has a coating comprising a polymer, and the mesh further comprises at least one active pharmaceutical ingredient. The active pharmaceutical agent is designed to elute from the mesh over time. The mesh substrate can be configured to reduce the mass of the anchorage device such that tissue in-growth and/or scar tissue formation at the treatment site is reduced. In some embodiments, the mesh substrate can be formed with a mesh having a low areal density. In some embodiments, the mesh substrate can include one or more apertures or pores to reduce the mass of the substrate.07-19-2012
20090306728METHODS AND APPARATUS FOR STIMULATING AND/OR SENSING NEURONS IN A PATIENT - Instruments and method of using instruments for implanting electrodes into a patient. The instrument can include a body configured to be implanted into a patient, an electrode contact carried by the body, and a marker carried by the body. The electrode contact has an electrically conductive surface exposed at a location along the body to sense electrical activity and/or deliver electrical stimulation to the target neural structure. The marker can include a transponder configured to be energized by a wirelessly transmitted excitation energy and to wirelessly transmit a location signal in response to the excitation energy. The instrument is tracked as it is implanted into the patient by time multiplexing the wirelessly transmitted excitation energy and the location signal such that the absolute location of the marker can be determined in real time.12-10-2009
20090093854Method of treating a rheumatic disorder using combination of transcutaneous electrical nerve stimulation and a ginsenoside - The present invention relates to a method of treating rheumatic disorders, and symptoms of arthritis specifically. The method involves utilizing transcutaneous electrical nerve stimulation (TENS) in combination with administration of a ginsenoside, such as Rb1.04-09-2009
20130072996Methods, Systems, and Devices for Treating Tinnitus with VNS Pairing - A method of treating tinnitus comprising measuring a patient's hearing, determining the patient's hearing loss and the patient's tinnitus frequency using the measurements of the patient's hearing, programming a clinical controller with the measurements of the patient's hearing, selecting a plurality of therapeutic tones, where the therapeutic tones are selected to be at least a half-octave above or below of the patient's tinnitus frequency, setting an appropriate volume for each of the plurality of tones, repetitively playing each of the plurality of therapeutic tones, and pairing a vagus nerve stimulation pulse train with each playing of a therapeutic tone, thereby reducing the patient's perception of tinnitus.03-21-2013
20110015687TISSUE TREATMENT SYSTEMS WITH HIGH POWERED FUNCTIONAL ELECTRICAL STIMULATION AND METHODS FOR REDUCING PAIN DURING TISSUE TREATMENTS - Methods, apparatus, and systems for transcutaneously treating tissue located beneath a skin surface with electromagnetic energy delivered from a treatment electrode. A portion of the treatment electrode is contacted with the skin surface. While maintaining the contact between the portion of the treatment electrode and the skin surface, the electromagnetic energy is delivered from the treatment electrode in a plurality of power pulses through the skin surface to the tissue over a treatment time with a time gap between each consecutive pair of the pulses to lower a level of pain perceived by a patient.01-20-2011
20110022103MEDICAL BLOOD-TREATING APPARATUS FOR THE EXTRA-CORPOREAL TREATMENT OF BLOOD - A medical blood-treating apparatus for the extra-corporeal treatment of blood has an extra-corporeal blood circuit. An arrangement for the extra-corporeal treatment of blood and an arrangement for electrical muscle stimulation (EMS) with which muscles of the patient can be stimulated in a targeted fashion during the dialysis treatment are provided. For this purpose, the arrangement for EMS has a means of generating electrical pulses, and has one or more electrodes connected to the means of generating electrical pulses. To enable targeted stimulation, the electrodes are applied to the patient's skin, e.g., the legs, during the blood treatment. Muscle stimulation during blood treatment may result in the dialysis treatment being more tolerable for the patient and increase the efficiency of the blood treatment. The blood-treating apparatus according to the invention allows an improvement in the efficiency of the blood treatment without any active sporting activity or exercise by the patient.01-27-2011
20090012573STIMULATOR COMBINED WITH AN INTRANASAL RESPIRATORY METHOD AND DEVICE FOR IMPROVED BREATHING - A nasal respiratory device combined with a neuromuscular stimulator adapted to provide electrical stimulation intraorally and/or intranasally to a patient for improving breathing and treating a respiratory disorder.01-08-2009
20080294209Decongestive therapy titration for heart failure patients using implantable sensor - Assessing decongestive therapy delivered to a heart failure patient involves use of an implantable sensor configured to sense a physiologic parameter indicative of the patient's diuresis status and a processor coupled to the implantable sensor. The sensor may comprise a thoracic fluid sensor, a heart sounds sensor, a cardiac chamber or arterial pressure sensor, a respiration sensor, or a blood chemistry sensor, for example. The processor is configured to determine if a target level of patient diuresis has been achieved based on a relationship between the sensed physiologic parameter and a threshold developed for the patient, and to produce an output in response to determining that the target level of patient diuresis has been achieved. The processor may be disposed in an implantable housing, in a patient-external housing, or in a network server system.11-27-2008
20080294208OPTIMIZING ENERGY TRANSMISSION IN A LEADLESS TISSUE STIMULATION SYSTEM - Method and systems for optimizing acoustic energy transmission in implantable devices are disclosed. Transducer elements transmit acoustic locator signals towards a receiver assembly, and the receiver responds with a location signal. The location signal can reveal information related to the location of the receiver and the efficiency of the transmitted acoustic beam received by the receiver. This information enables the transmitter to target the receiver and optimize the acoustic energy transfer between the transmitter and the receiver. The energy can be used for therapeutic purposes, for example, stimulating tissue or for diagnostic purposes.11-27-2008
20100198282DEVICES FOR VESTIBULAR OR CRANIAL NERVE STIMULATION - A nerve tissue stimulator configured for contacting to or insertion in the body of a subject to stimulate a tissue therein, said probe comprising: (a) a support configured for contacting to or positioning adjacent a tissue of said subject; (b) at least one thermoelectric device (TED) on said support and positioned for thermally stimulating said nerve tissue.08-05-2010
20110282404Methods for Enhancing Exposure Therapy Using Vagus Nerve Stimulation - Disclosed is a method of enhancing exposure therapy comprising providing an exposure therapy to a patient and stimulating the patient's vagus nerve at the same time as the exposure therapy. Also disclosed is a post-traumatic stress disorder therapy method comprising providing an exposure event to a patient and stimulating the patient's vagus nerve during the exposure event. Also disclosed is a phobia disorder therapy method comprising providing an extinction event to a patient and stimulating the patient's vagus nerve during the extinction event. Also disclosed is an obsessive compulsive disorder therapy method comprising providing a therapy event to a patient and stimulating the patient's vagus nerve during the therapy event. Also disclosed is an addiction disorder therapy method comprising providing a therapy event to a patient and stimulating the patient's vagus nerve during the therapy event.11-17-2011
20100280563DEVICE AND METHOD FOR DETECTING AND TREATING A MYOCARDIAL INFARCTION USING PHOTOBIOMODULATION - In an implantable medical device and a method for treating cardiac tissue of a heart of a patient with therapeutic light, a myocardial infarction is detected and a location the myocardial infarction is identified. A therapy session is initiated by selectively activating one or more of a number of light emitting units arranged in at least one medical lead connectable to the implantable medical device, to emit therapeutic light toward the detected location of the myocardial infarction upon detection of an occurrence of the myocardial infarction.11-04-2010
20120290026SYSTEMS AND METHODS FOR TREATING SUPRAVENTRICULAR ARRHYTHMIAS - In various method embodiments, a supraventricular arrhythmia event is detected, and a supraventricular arrhythmia treatment, including neural stimulation to elicit a sympathetic response, is delivered in response to a detected supraventricular arrhythmia event. Some embodiments detect a precursor for a supraventricular arrhythmia episode, and deliver prophylactic neural stimulation to avoid the supraventricular arrhythmia event. Some embodiments detect a supraventricular arrhythmia episode, and deliver therapeutic neural stimulation for the supraventricular arrhythmia event.11-15-2012
20120290025LEADLESS IMPLANTABLE MEDICAL DEVICE WITH OSMOTIC PUMP - Techniques for delivering genetic material to a target tissue site of a patient via a leadless implantable medical device that includes a pump and a stimulation energy delivery element are described. In some examples, delivery of genetic material to the target tissue site causes transgene expression of tissue at the target tissue site, which may result in generation of new cells or modified properties of existing cells of the target tissue site, facilitating more effective and efficient treatment of a disorder of the patient.11-15-2012
20120290023Method, device and system for modulating an activity of brown adipose tissue in a vertebrate subject - Devices, systems, and methods are disclosed herein for treatment of a disease, disorder, or condition in a vertebrate subject. A device is provided that includes one or more cooling elements configured to be applied to one or more tissues of a vertebrate subject to modulate at least one activity of brown adipose tissue of the vertebrate subject, and a programmable controller configured to provide instructions to the one or more cooling elements in response to information regarding one or more physiological conditions of the vertebrate subject.11-15-2012
20120290024TRANSVENOUS RENAL NERVE MODULATION FOR TREATMENT OF HYPERTENSION, CARDIOVASCULAR DISORDERS, AND CHRONIC RENAL DISEASES - A transvenous renal nerve modulation system comprises: a blood pressure monitoring device to be implanted in a patient to monitor the patient's blood pressure; one or more transvenous renal nerve modulation leads to be implanted in one or more renal blood vessels of the patient; a pulse generator coupled to the transvenous renal nerve modulation leads to deliver electrical pulses to the one or more transvenous renal nerve modulation leads for modulating renal nerves of the patient; and a control unit coupled to the blood pressure monitoring device and the pulse generator to control delivery of the electrical pulses by the pulse generator based on the patient's blood pressure from the blood pressure monitoring device. The pulse generator delivers high frequency pulses of greater than about 10 Hz to the transvenous renal nerve modulation leads if the patient's blood pressure is greater than a high blood pressure threshold.11-15-2012
20110288602Method and Device for Enhanced Blood Flow - A non-invasive method and device for promoting a localized change in a flow of blood through a blood vessel in a limb segment of a body by a series of electrically stimulated contractions of muscle tissue in the limb segment, the method including the steps of: (a) providing a device including: (i) first, second and third electrodes, each adapted to operatively contact the limb segment; (ii) a signal generator, operatively connected to the electrodes, adapted to produce a series of electrical impulses to the limb segment via the electrodes, and (iii) a control unit adapted to control the signal generator to produce the series of electrical impulses; (b) positioning the electrodes on the limb segment, wherein the first electrode is positioned on a lower end of the lower leg, the second electrode is positioned on the lower leg, and the third electrode is positioned on an upper end of the lower leg, whereby the first and third electrodes are disposed on opposite ends of the lower leg, and the second electrode and one of the first and third electrodes are disposed on a same end of the lower leg; (c) effecting a sequence of muscular contractions of the lower leg, by operations including: (i) applying a first electrical impulse between the electrodes on the same end of the lower leg to induce a first muscular contraction of a first portion of the tissue; and (ii) applying at least a second electrical impulse between the first and third electrodes to induce a longitudinal muscular contraction of a second portion of the muscular tissue; and (d) repeating operations (i) and (ii), to repeatedly induce the contractions, to effect the increased flow of blood.11-24-2011
20110295332QUANTITATIVE MULTIVARIATE ANALYSIS OF SEIZURES - Methods, including a method, comprising selecting a plurality of dependent variables relating to each of a plurality of seizures in a patient; selecting a plurality of independent variables, wherein each independent variable comprises a therapy parameter, a therapy delivery parameter, a temporal factor, an environmental factor, or a patient factor; quantifying at least one relationship between each of at least two dependent variables and each of at least two independent variables; and performing an action in response to said quantifying, selected from reporting said at least one relationship, assessing an efficacy of a therapy, assessing an adverse effect of said therapy, providing a therapy modification recommendation, or adjusting said therapy. A medical device system capable of implementing a method. A non-transitory computer readable program storage medium containing instructions that, when executed by a computer, perform a method.12-01-2011
20110295331LASER-BASED NERVE STIMULATORS FOR, E.G., HEARING RESTORATION IN COCHLEAR PROSTHESES AND METHOD - Apparatus and method for optical- or optical-and-electrical stimulation of e.g., auditory nerve pathways, for example spiral ganglion in the cochlea or neurons in the cochlear nerve. Several configurations for guiding and directing the optical stimulation are disclosed. Several configurations for guiding and directing the electrical field (used in some embodiments, for sensitization) in and through the destination tissue to which the optical stimulation is directed are disclosed. In some embodiments, and array of IR VCSELs emit stimulation light, in particular to tissue in the cochlea for restoring hearing. In some embodiments, an electrical signal is also applied in a manner that reduces the amount of light in a pulse that is otherwise needed to elicit a NAP. In some embodiments, a heat dissipater is used to spread the heat generated by operation of the lasers and their circuits, to avoid heat damage to the tissue.12-01-2011
20090171406ELECTRICALLY CONDUCTING SCAFFOLDS FOR CELL-BASED PACING - The invention provides a biological electrode including a first biocompatible polymer, an electrically conducting biocompatible polymer and mammalian donor cells and an electrical stimulation system for delivering electrical stimulation into target tissue including target cells. The system includes a biological electrode including an electrically conductive polymeric matrix and mammalian donor cells embedded in the electrically conductive polymeric matrix.07-02-2009
20090099612ELECTRICAL CONDUCTOR HAVING A BIOERODIBLE COATING - An apparatus includes an elongate member having a proximal end portion and a distal end portion. The proximal end portion is configured to receive an electrical current from a current source. The elongate member is configured to transmit the electrical current from the proximal end portion to the distal end portion. At least a portion of the elongate member is configured to be disposed within a body of a patient. An electrode is coupled to the distal end portion of the elongate member. The electrode is configured to transmit a portion of the electrical current from the distal end portion of the elongate member to a target bodily tissue. A coating is disposed on at least a portion of the elongate member. The coating is formulated to release at least one of a therapeutic agent, a conductive agent, and/or an insulative agent into the body of the patient in response to the electrical current being transmitted from the proximal end portion to the distal end portion of the elongate member.04-16-2009
20120191149Integrated Resuscitation - A resuscitation system that includes at least two defibrillation electrodes configured to be applied to the exterior of the chest of a patient for delivering a defibrillation shock, a source of one or more ECG signals from the patient, a defibrillation circuit for delivering a defibrillation shock to the defibrillation electrodes, a control box that receives and processes the ECG signals to determine whether a defibrillation shock should be delivered or whether CPR should be performed, and that issues instructions to the user either to deliver a defibrillation shock or to perform CPR, wherein the determination of whether CPR should be performed and the instructions to perform CPR can occur at substantially any point during a rescue.07-26-2012
20120191147ELECTRONIC SKIN PATCH FOR REAL TIME MONITORING OF CARDIAC ACTIVITY AND PERSONAL HEALTH MANAGEMENT - A novel wearable electronic skin patch sensor device configured for the real time acquisition, processing and communicating of cardiac activity and other types of biological information within a wired or wireless network is disclosed. A system level scheme for networking the sensor device with client devices that include intelligent personal health management appliances, cellular telephones, PDAs, portable computers, personal computers, RFID Tags and servers is disclosed. The sensor device and the system enable distributed processing, archival and correlation of the biological information with biometrics, gastronomic information, user profiles and health factors that include height, weight, blood pressure and physical activity facilitating real time personal health management at any time and any place.07-26-2012
20100211122HOLDER FOR SIMULTANEOUSLY APPLYING A GEL PACK AND A TRANSCUTANEOUS ELECTRICAL NERVE/MUSCLE STIMULATOR - A device for application to a body part for the treatment of symptoms of injury or pain, comprising a holder for simultaneously applying (1) a thermal device capable of retaining hot or cold, and (2) a transcutaneous electrical nerve/muscle stimulator, whereby to allow the simultaneous application to a body part of transcutaneous electrical nerve/muscle stimulation and either hot or cold therapy. The holder can have a pocket for receiving the thermal device and a front surface bearing the nerve/muscle stimulator, for example, by hook and loop material, or adhesive, enabling the activatable surface of the nerve/muscle stimulator to be applied to the body part simultaneously with the hot or cold therapy of the gel pack in the pocket.08-19-2010
20120191148SYSTEM FOR CORRELATING ENERGY FIELD CHARACTERISTICS WITH TARGET PARTICLE CHARACTERISTICS IN THE APPLICATION OF AN ENERGY FIELD TO A LIVING ORGANISM FOR TREATMENT OF INVASIVE AGENTS - The Energy Field and Target Correlation System automatically correlates the characteristics of target particles and a living organism to compute the characteristics of an energy field that is applied to a living organism to activate the target particles which are bound to or consumed by invasive agents in the living organism to produce detectable effects which can be used to treat the invasive agents. The energy field must be crafted to properly control the response and localize the extent of the illumination. The System automatically selects a set of energy field characteristics, including: field type, frequency, field strength, duration, field modulation, repetition frequency, beam size, and focal point. The determined energy field characteristics then are used to activate field generators to generate the desired energy field.07-26-2012
20090099613COMBINATION ELECTRICAL STIMULATING AND INFUSION DEVICE AND METHOD - A combined electrical and chemical stimulation lead is especially adapted for providing treatment to intervertebral discs. The combination lead may be placed proximate to intervertebral disc cellular matrix and nucleus pulposus tissue to promote tissue regeneration and repair, as well as nociceptor and neural tissue modulation. The stimulation lead includes electrodes that may be selectively positioned along various portions of the stimulation lead in order to precisely direct electrical energy to stimulate the target tissue. The lead also includes a central infusion passageway or lumen that communicates with various infusion ports spaced at selected locations along the lead to thereby direct the infusion of nutrients/chemicals to the target tissue. One embodiment utilizes a dissolvable matrix for infusion as opposed to remote delivery through an infusion pump.04-16-2009
20100114192METHODS AND SYSTEMS FOR STIMULATING A MOTOR CORTEX OF THE BRAIN TO TREAT A MEDICAL CONDITION - Methods of treating a medical condition include applying at least one stimulus to a motor cortex within a brain of a patient with an implanted system control unit in accordance with one or more stimulation parameters. Systems for treating a medical condition include a system control unit implanted within the patient that is configured to apply at least one stimulus to a motor cortex within a brain of a patient in accordance with one or more stimulation parameters.05-06-2010
20090149899Functional Shoes In Which Stimulant For Extension Growth Acceleration Is Equipped - The present invention relates to a pair of functional shoes, which enables both physical stimulation and electrical stimulation to be transmitted to the heel portions of feet and specific portions of ankles, which are helpful in promoting height growth, using the force that is generating while walking, thus stimulating growth plates. Each of the functional shoes an ankle contact member mounted to the heel counter of the shoe, which supports the rear portion of a foot, which ranges from the heel of a foot to an ankle, formed in a shape that corresponds to the concave shape of the rear portion of the ankle, and coming into contact with an ankle stimulation portion; an ankle stimulating member mounted from the inside of a shoe outsole to the ankle contact member, and transmitting physical stimulation to the ankle stimulation portion, which is the concave rear portion of the ankle malleolus, using force that is applied by the foot while walking; a heel stimulating member mounted in the shoe outsole, which corresponds to the central portion of the rear portion of a sole, formed to have hardness higher than the outsole, and transmitting load stimulation, caused by applied force, to a heel stimulation portion, which corresponds to the central portion of the rear portion of the sole; and an electrical stimulation unit, comprising a power generation device which is mounted in the shoe outsole and generates power, and power generation points which are formed on an ankle stimulation part and/or the heel stimulation portion.06-11-2009
20090149901INTEGRATED EXTERNAL CHEST COMPRESSION AND DEFIBRILLATION DEVICES AND METHODS OF OPERATION - Integrated devices for performing external chest compression (ECC) and defibrillation on a person and methods using the devices. Integrated devices can include a backboard, at least one chest compression member operably coupled to the backboard, and a defibrillator module operably coupled to the backboard. The integrated devices can include physiological sensors, electrodes, wheels, controllers, human interface devices, cooling modules, ventilators, cameras, and voice output devices. Methods can include defibrillating, pacing, ventilating, cooling, and performing ECC in an integrated, coordinated, and/or synchronous manner using the full capabilities of the device. Some devices include controllers executing methods for automatically performing the coordinated activities utilizing the device capabilities.06-11-2009
20100268289METHOD AND SYSTEM FOR THE PREDICTION OF CARDIAC ARRHYTHMIAS, MYOCARDIAL ISCHEMIA, AND OTHER DISEASED CONDITION OF THE HEART ASSOCIATED WITH ELEVATED SYMPATHETIC NEURAL DISCHARGES - Methods and systems are provided for determining an increased likelihood of the occurrence of a cardiac arrhythmia, myocardial ischemia, congestive heart failure and other diseased conditions of the heart associated with elevated sympathetic neural discharges in a patient. The methods and systems comprise monitoring the sympathetic neural discharges of a patient from the stellate ganglia, the thoracic ganglia, or both, and detecting increases in the sympathetic neural discharges. The methods and systems may further comprise delivering therapy to the patient in response to a detected increase in the sympathetic neural discharge, such as delivering one or more pharmacological agents; stimulating myocardial hyperinnervation in the sinus node and right ventricle of the heart of the patient; and applying cardiac pacing, cardioversion or defibrillation shocks. Pharmacologic agents which may be used in connection with the delivery of include those which are known to exert anti-arrhythmic effect and anti-convulsant agents, such as phenytoin, carbamazepine, valproate, and phenobarbitone. Other pharmacologic agents may be used to treat impending myocardial ischemia and other diseased conditions of the heart associated with elevated sympathetic neural discharges.10-21-2010
20090149900TRANSVASCULAR NEURAL STIMULATION DEVICE - This document discusses, among other things, apparatus, systems, and methods for transvascularly stimulation of a nerve or nerve trunk. In an example, an apparatus is configured to transvascularly stimulate a nerve trunk through a blood vessel. The apparatus includes an expandable electrode that is chronically implantable in a blood vessel proximate a nerve trunk. The expandable electrode is configured to abut a predetermined surface area of the vessel wall along a predetermined length of the vessel. An electrical lead is coupled to the expandable electrode. An implantable pulse generator is coupled to the lead and configured to deliver an electrical stimulation signal to the electrode through the lead. In an example method, an electrical signal is delivered from an implanted medical device to an electrode chronically implanted in a blood vessel proximate a nerve trunk to transvascularly deliver neural stimulation from the electrode to the nerve trunk.06-11-2009
20090149896System for chemical modulation of neural activity - Methods and related systems for modulating neural activity by repetitively blocking conduction in peripheral neural structures with chemical blocking agents are disclosed. Methods and systems for reversing effects of chemical blocking agents and/or for producing substantially permanent conduction block are also disclosed.06-11-2009
20090149895Method and system for cyclical neural modulation based on activity state - Methods and related systems for modulating neural activity by repetitively or cyclically blocking conduction in a peripheral neural structure are disclosed. Timing of delivery of blocking stimuli may be based upon overall activity level of the subject or use/activity of a portion of the body of a subject.06-11-2009
20110264155IMPLANTABLE HEARING PROSTHESIS - An implantable hearing prosthesis comprising an implantable upgrade module including a pre-processing unit configured to generate audio signals based on microphone information; and a implantable main module, physically separate from and electrically connected to the upgrade module. The implantable main module comprises a sound processing unit configured to generate stimulation information based on the audio signals received from the pre-processing unit, and a stimulator unit configured to generate stimulation signals based on the stimulation information. The hearing prosthesis also comprises a stimulation module configured to deliver the stimulation signals to a recipient.10-27-2011
20120109234METHOD OF STIMULATING FASTIGIUM NUCLEUS TO TREAT NEUROLOGICAL DISORDERS - A method of treating a neurological disorder comprises introducing an electrical stimulation lead within a patient's head, locating the stimulation lead within the 405-03-2012
20120109233PORTABLE COMBINED STIMULATION DEVICE FOR ALLEVIATING MENSTRUAL PAIN - The present invention relates to a portable device for alleviating menstrual pain through transcutaneous electrical nerve stimulation (TENS) and thermal stimulation. More particularly, the present invention relates to a portable device for alleviating menstrual pain by applying transcutaneous electrical nerve stimulation to the abdominal and back area of a user through the use of a planar heart embedded in the stimulating electrode pad. The stimulating electrode pad is a patch type one which is attachable/detachable to/from any body part with menstrual pain. The portable device for alleviating menstrual pain in the public area of the user according to the present invention comprises, a menstrual pain alleviating unit and a main body unit. The menstrual pain alleviating unit includes a transcutaneous stimulating electrode pad portion provided with a transcutaneous stimulating electrode to apply transcutaneous stimulation to the abdominal or back area of the user, and a planar heater portion provided with a planar hater to apply thermal stimulation to the abdomen of the user. The main body unit includes a power portion for supplying power to the menstrual pain alleviating unit, and an operation processing portion for generating a transcutaneous stimulating electrode control signal for controlling the transcutaneous stimulating electrode pad portion and a planar heater control signal for controlling the planar heater portion. The menstrual pain alleviating unit further includes a temperature sensing portion provided with a temperature sensor mounted on the planar heater portion to sense the temperature of the planar heater portion, and an A/D converting portion for converting the signal output from the temperature sensing portion into a digital signal.05-03-2012
20120109232THERMOSTIMULATION APPARATUS - A thermostimulation apparatus is disclosed that includes heating and cooling means, and in various embodiments the heating and cooling means are heating and cooling pads, or at least one pad capable of both heating and cooling, the latter possibly being one or more Peltier elements. Certain embodiments also include heat sink means and heat exchanger means, and/or electrical stimulation, and the cooling means can include a refrigerant.05-03-2012
20120109231SYSTEM AND APPARATUS TO MONITOR BIOPACEMAKER MATURATION - The present invention includes systems, devices, and methods relating to the monitoring of the functional maturation of biological interventions effecting cardiac pacing.05-03-2012
20110196438THERAPY DEVICE AND METHOD FOR TREATING UNDERLYING TISSUE USING ELECTRICAL AND ACOUSTIC ENERGIES - A device for subcutaneous adipose tissue skin treatment applies both radio frequency energy (RF) and ultrasound energy (US) into the skin from a single electrode. The electrode may be cooled via a chilled liquid cooling system, thereby indirectly also cooling the skin. An infrared thermometer on the device may measure skin temperature. A passive electrode may be placed on the patient's skin in a location remote from the treatment site.08-11-2011
20110172725NERVE STIMULATOR AND METHOD USING SIMULTANEOUS ELECTRICAL AND OPTICAL SIGNALS - An apparatus and method for stimulating animal tissue (for example to trigger a nerve action potential (NAP) signal in a human patient) by application of both electrical and optical signals for treatment and diagnosis purposes. The application of an electrical signal before or simultaneously to the application of a NAP-triggering optical signal allows the use of a lower amount of optical power or energy than would otherwise be needed if an optical signal alone was used for the same purpose and effectiveness. The application of the electrical signal may precondition the nerve tissue such that a lower-power optical signal can be used to trigger the desired NAP, which otherwise would take a higher-power optical signal were the electric signal not applied. Some embodiments include an implanted nerve interface having a plurality of closely spaced electrodes placed transversely and/or longitudinally to the nerve and a plurality of optical emitters.07-14-2011
20110172726CRANIAL ELECTROSTIMULATION METHOD AND EQUIPMENT - A method and equipment for conducting cranial electrostimulation on a patient are provided. Suitable electrodes are attached to the head of the patient cause electrostimulation currents to be created in response to pulses applied to the electrodes. Music is simultaneously audible to the patient. The pulses, or sequences of pulses, are generated at a frequency that is varied according to the rhythm, beat of music that is audible to the patient. The equipment comprises a cranial electrostimulation pulse generator and associated electrodes for applying pulses to the head of a patient, and a sound signal generator with at least one associated loudspeaker that is typically a pair of earphones, for generating audible sound. A controller controls the frequency at which pulses or sequences of pulses are generated by the cranial electrostimulation pulse generator such that the frequency is varied according to the rhythm, beat or tempo of the music.07-14-2011
20120143272METHOD FOR TREATING DAMAGED TISSUE OF THE CNS - Devices and methods for treating diseases associated with loss of neuronal function are described. The methods are designed to promote proliferation, differentiation, migration, or integration of endogenous progenitor stem cells of the central nervous system (CNS). A therapy, such as an electrical signal or a stem cell enhancing agent, or a combination of therapies, is applied to a CNS region containing endogenous stem cells or a CNS region where the endogenous stem cells are predicted to migrate and eventually reside, or a combination thereof.06-07-2012
20080208269IMPLANTABLE TISSUE PERFUSION SENSING SYSTEM AND METHOD - A medical device system for sensing cardiac events that includes a plurality of electrodes sensing cardiac signals utilized to identify a cardiac event, a plurality of light sources capable of emitting light at a plurality of wavelengths, and a detector to detect the emitted light. A processor determines a plurality of light measurements in response to the emitted light detected by the detector, determines changes in perfusion in response to first changes in the plurality of light measurements in a direction indicative of a decrease in blood oxygenation and second changes in a direction indicative of a decrease in blood volume, and adjusts delivery of therapy by the device in response to the determined loss of perfusion.08-28-2008
20090287264APPLIANCE AND SEQUENCE OF PULSES FOR THE APPLICATION OF ELECTROTHERAPY - The invention relates to a transcutaneous nerve and/or muscle stimulation appliance with electrodes destined to apply a sequence of electric pulses to the skin of a person, providing means that allow the generation of multiphase pulses during a stimulation period, these means allowing the generation of successive sequences of the above-mentioned multiphase pulses during successive stimulation periods with a frequency between 10 Hz and 100 Hz, more in particular a frequency of approximately 50 Hz, these means furthermore allowing a rest period between successive stimulation periods, during which rest period a sequence of electric pulses is generated with a frequency ranging from 0.5 Hz to 5 Hz and with an amplitude lower than that of the above-mentioned multiphase pulses.11-19-2009
20090287265AGITATOR TO STIMULATE THE CENTRAL NERVOUS SYSTEM - A tactile and audible sensation can be provided to a patient using a coiled or scrolled film in response to a received control signal. The tactile and audible sensation can be configured to stimulate the patient's central nervous system to sufficiently interrupt and undesirable sleep behavior of the patient, but avoid significantly changing a sleep state of the patient.11-19-2009
20090292329APPARATUS FOR DELIVERY OF PHARMACEUTICALS TO THE COCHLEA - An implantable tissue-stimulating device, such as a cochlear implant, having a resiliently flexible elongate member (11-26-2009
20110270331COMBINATION HEART ASSIST SYSTEMS, METHODS, AND DEVICES - The various embodiments disclosed herein relate to combination heart assist systems, methods, and devices that include both an electrical therapy device and a mechanical heart assist device. Various operational modes can be implemented using these embodiments, including a synchronized pacing mode, an internal CPR mode, and an internal workout mode.11-03-2011
20110208257CRANIAL ELECTROSTIMULATION METHOD, EQUIPMENT AND ELECTRODE UNIT - A method of conducting cranial electrostimulation on a patient is provided as well as equipment therefore. Suitable electrodes are attached to the head of the patient and electrostimulation currents are created in response to pulses applied to the electrodes. Multiple electrodes are employed and the electrostimulation currents are caused to flow between different pairs of electrodes of the multiplicity thereof sequentially in either a random order or a predetermined order. Typically, the multiple electrodes are arranged in two sets thereof in which instance the different pairs of electrodes are selected one from one set and one from the other set so that current flows between the electrodes of only one pair at any one time. The sets of electrodes are generally engaged with the ears of a patient. The polarity of the pulses applied to the various pairs of electrodes may be varied sequentially or randomly.08-25-2011
20110270332THERAPY USING PERTURBATION AND EFFECT OF PHYSIOLOGICAL SYSTEMS - Methods for treating a patient and further to devices for performing such treatment, e.g., methods and devices to perturb at least one physiological system and deliver therapy to the patient based on the effects of such perturbation. For example, a method for using an implantable medical device is disclosed that involves delivering electrical stimuli to an efferent nerve associated with the selected organ. Afferent electrical activity is monitored during delivery of electrical stimuli to the efferent nerve, the monitored afferent electrical activity includes an indirect component of a compound action potential (CAP). A status of the selected organ is assessed based upon the indirect component. A determination is made as to whether to deliver therapy to the selected organ in response to assessing the status of the selected organ.11-03-2011
20090299420METHOD AND APPARATUS FOR CRYOTHERAPY AND PACING PRECONDITIONING - A method and apparatus are described for delivering myocardial pacing and cryotherapy in conjunction with a coronary revascularization procedure using one catheter/stent system. In one embodiment, a balloon-stent delivery platform incorporates pacing electrode(s) on or near the distal tip for myocardial pacing.12-03-2009
20100204741SYSTEMS FOR REGULATION OF BLOOD PRESSURE AND HEART RATE - A method and apparatus for treating a condition associated with impaired blood pressure and/or heart rate in a subject comprising applying an electrical treatment signal, wherein the electrical treatment signal is selected to at least partially block nerve impulses, or in some embodiments, to augment nerve impulses.08-12-2010
20100004709Physiologic stimulation for stroke treatment - Methods and devices are disclosed that provide treatment for neurological strokes and other conditions related to obstructed, hemorrhagic or compromised vascular circulation.01-07-2010
20100004706PACING SYSTEM CONTROLLER INTEGRATED INTO INDEFLATOR - Systems and methods for temporarily pacing a patient's heart are provided. One system includes a vascular treatment system having a vascular access system and a therapy system. The therapy system includes an indeflator and an elongate medical device and the elongate medical device has an inflatable member and an electrode. The indeflator is adapted to provide pressurized fluid to the inflatable member and electrical signals to the electrode, with its operation manually or automatically controlled. Devices for electrically and fluidly coupling the indeflator and the elongate medical device are also provided.01-07-2010
20100004704METHOD FOR TREATING A CARDIAC RHYTHM DISTURBANCE - A method is provided for treating a subject. One step of the method includes performing cardiac surgery on the subject. Next, a cardiac drug is administered to the subject. An electric current is then applied to a cardiac fat pad of the subject to reduce an adverse effect caused by the cardiac drug.01-07-2010
20100137927MULTIFUNCTIONAL CARDIAC PACEMAKER SYSTEM - A pacemaker system 06-03-2010
20080288008Cardiac Stimulation System and Method - A cardiac stimulation assembly includes an energy source coupled to an energy emitter that extends form a delivery member into a region of tissue in the heart. An array of the emitters are adapted to extend from a delivery assembly and into unique locations along the region of tissue, such as by use of extendable, pre-shaped needles. A volume of conductive agent is delivered into the region and enhances stimulation of the region with the energy emitter. The agent may be an injectable preparation of living cells that express production of connexin, e.g. connexin 43, and may be genetically modified to over-express such production. The agent may include a non-living material, such as conductive polymer or metal or combination thereof. The combination of energy emitters and conductive agent enhances stimulation of the region. Delivering the stimulation assembly and conductive agent into the interventricular septum allows for improved biventricular septal pacing.11-20-2008
20100145399MULTIFUNCTION DEVICES AND METHODS OF USING THE MULTIFUNCTION DEVICES - Devices which are used for performing multiple modes of electro, vacuum and ultrasound therapy are disclosed as well as methods of using those devices. One device for providing a constant current and/or a constant voltage to regions of a patient's body includes a housing, at least one microprocessor for generating at least one signal, at least one amplifier circuit for amplifying the one or more signals, at least one feedback circuit for delivering at least one constant current to a patient's body, at least one lead wire socket located on the exterior of the housing, at least one pair of electrodes connected to the one or more lead wire sockets, wherein the electrodes are placed in communication with at least one region of the patient's body so that an output current and or voltage is delivered to one or more of the skin regions of the patient's body. Additionally, a controller is used to activate the constant current and/or voltage and it is also used to select one or more selected modes for the constant current and/or voltage.06-10-2010
20100004708METHOD AND SYSTEM FOR NERVE STIMULATION AND CARDIAC SENSING PRIOR TO AND DURING A MEDICAL PROCEDURE - A method of performing a medical procedure, such as surgery, is provided. A nerve is stimulated in order to adjust the beating of the heart to a first condition, such as a stopped or slowed condition. The medical procedure is performed on the heart or another organ. The stimulation of the nerve is stopped in order to adjust the beating of the heart to a second condition, such as a beating condition. The heart itself may also be stimulated to a beating condition, such as by pacing. The stimulation of the nerve may be continued in order to allow the medical procedure to be continued. A sensor to sense a characteristic of a fluid or tissue, such as an impending contraction, may be also used during the medical procedure. Systems and devices for performing the medical procedure are also provided.01-07-2010
20100004705Systems, Methods and Devices for Treating Tinnitus - Systems, methods and devices for paired training include timing controls so that training and neural stimulation can be provided simultaneously. Paired trainings may include therapies, rehabilitation and performance enhancement training. Stimulations of nerves such as the vagus nerve that affect subcortical regions such as the nucleus basalis, locus coeruleus or amygdala induce plasticity in the brain, enhancing the effects of a variety of therapies, such as those used to treat tinnitus, stroke, traumatic brain injury and post-traumatic stress disorder.01-07-2010
20090326595Prediction and Prevention of Cardiovascular Insult - In a method of providing therapy to a patient to prevent an occurrence of a dangerous cardiac event, a cardiac signal sensed over multiple cardiac cycles is received. A risk of impending cardiovascular insult is determined, using the received cardiac signal, by assessing an indicator of proarrhythmogenic substrate and a change in sympathovagal balance. A therapy comprising acupuncture to modulate sympathovagal balance is administered based on the determined risk.12-31-2009
20090099611BIOLOGICAL PACEMAKERS INCLUDING MUTATED HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED (HCN) CHANNELS - A composition for implantation into cardiac tissue includes a biological pacemaker that, when implanted, expresses an effective amount of a mutated hyperpolarization-activated and cyclic nucleotide-gated (HCN) isoform to modify I04-16-2009
20090210019TREATMENT OF EXCESS WEIGHT BY NEURAL DOWNREGULATION IN COMBINATION WITH COMPOSITIONS - A method and system for designing a therapy or for treating a condition associated with excess weight in a subject comprising applying a neural conduction block to the vagus nerve at a blocking site with the neural conduction block selected to at least partially block nerve impulses on the vagus nerve at the blocking site and administering a composition comprising an effective amount of an agent that alters the energy balance of the subject.08-20-2009
20090222053METHOD OF ROUTING ELECTRICAL CURRENT TO BODILY TISSUES VIA IMPLANTED PASSIVE CONDUCTORS - The invention provides an implant, system and method for electrically stimulating a target tissue to either activate or block neural impulses. The implant provides a conductive pathway for a portion of electrical current flowing between surface electrodes positioned on the skin and transmits that current to the target tissue. The implant has a passive electrical conductor of sufficient length to extend from subcutaneous tissue located below a surface cathodic electrode to the target tissue. The conductor has a pick-up end which forms an electrical termination having a sufficient surface area to allow a sufficient portion of the electrical current to flow through the conductor, in preference to flowing through body tissue between the surface electrodes, such that the target tissue is stimulated to either activate or block neural impulses. The conductor also has a stimulating end which forms an electrical termination for delivering the current to the target body tissue.09-03-2009
20090240294Method for controlling flow of eggs in a uterine tube - There is provided a method for controlling a flow of eggs in a uterine tube formed by a uterine tube wall of a patient. The method comprises gently constricting (i.e., without substantially hampering the blood circulation in the uterine tube wall) at least one portion of the uterine tube wall to influence the flow of eggs in the uterine tube, and stimulating the constricted wall portion to cause contraction of the uterine tube wall portion to further influence the flow of eggs in the uterine tube. The method can be used for restricting or stopping the flow of eggs in the uterine tube, or for actively moving the fluid in the uterine tube, with a low risk of injuring the uterine tube.09-24-2009
20090254134Hybrid ultrasound/electrode device for neural stimulation and recording - An invasive device that uses electrodes in conjunction with ultrasound is used to enhance and localize electrical recordings and stimulation of neurons. The current design is confined to operate within an elongated geometry for ease of insertion and minimal disruption to brain tissue.10-08-2009
20090149898Systems and Methods for Providing Targeted Neural Stimulation Therapy to Address Neurological Disorders, Including Neuropyschiatric and Neuropyschological Disorders - Systems and methods for providing targeted neural stimulation therapy to address neurological disorders, including neuropsychiatric and neuropsychological disorders are disclosed. A method for treating a patient's neurological disorder in accordance with a particular embodiment includes, in a patient identified as having at least one of a neuropsychological disorder and a neuropsychiatric disorder, implanting at least one stimulation electrode within the patient's skull cavity, and outside a cortical surface of the patient's brain. The electrode is implanted at a location in a range of about 15 mm to about 35 mm anterior to a precentral sulcus reference point that is positioned at the precentral sulcus and at the patient's middle frontal gyrus. The method can further include treating the patient's disorder by applying electrical stimulation to the patient via the at least one stimulation electrode.06-11-2009
20090259267Implantable Neuro-Stimulation Electrode With Fluid Reservoir - An implantable electrode with a fluid reservoir is described. An implantable electrode carrier has an outer surface with electrode contacts for electrically stimulating nearby neural tissue. An enlarged fluid storage reservoir within the electrode carrier stores a treatment volume of therapeutic fluid for an extended therapeutic treatment period. At least one fluid delivery port connects the fluid storage reservoir to the outer surface of the electrode carrier for delivering the therapeutic fluid from the fluid storage reservoir to the outer surface.10-15-2009
20090259268METHOD AND APPARATUS FOR DELIVERING COMBINED ELECTRICAL AND DRUG THERAPIES - A cardiac rhythm management (CRM) system includes an implantable medical device that delivers combined electrical and drug therapies. The implantable medical device includes a drug reservoir that is refillable after implantation. In one embodiment, the implantable medical device includes an implantable housing encapsulating a pulse generator circuit and a drug delivery device. In another embodiment, the implantable medical device includes an implantable pulse generator and an implantable drug delivery device fastened to each other.10-15-2009
20090149897System for transdermal chemical modulation of neural activity - Methods and related systems for modulating neural activity by repetitively blocking conduction in peripheral neural structures with chemical blocking agents are disclosed. Systems for transdermal delivery of chemical blocking agents are disclosed. Methods and systems for reversing effects of chemical blocking agents and/or for producing substantially permanent conduction block are also disclosed.06-11-2009
20100160987MUSCLE THERAPY SYSTEM - Certain embodiments provide a system for treating diminished muscle function that includes an electrical member that delivers electrical energy to a portion of a mammalian body having a dysfunctional muscle; a joint motion assembly that couples to the body and provides joint motion to a joint to which the dysfunctional muscle ordinarily provides motion; and a control unit that controls a timing of electrical energy delivery by the member and an amount of electrical energy delivered by the member; the timing of electrical energy delivery is controlled to occur while the joint is positioned near an inflection point between the opposing joint movements in the cycle, and while motion is being provided to the joint by the joint motion assembly. The amount of electrical energy delivered is effective to result in a depolarization of at least one of the dysfunctional muscle and a nerve that innervates the dysfunctional muscle.06-24-2010
20100160986UPPER EXTREMITY MUSCLE THERAPY SYSTEM - Some embodiments of the present invention provide systems and methods for treating diminished muscle function. Some systems include an electrical member that delivers electrical energy to a hand region of a body that comprises a dysfunctional muscle; a joint motion assembly that couples to the body and provides, to a joint adjacent the dysfunctional muscle, a motion made up of a cycle of opposing joint movements; and a control unit that provides an operator of the system with control of a timing of electrical energy delivery and an amount of electrical energy delivered. Some systems time the electrical energy delivery to occur when the moving joint is near an inflection point and deliver electrical energy delivered in amounts effective to result in a depolarization of the dysfunctional muscle, a nerve in proximity of the joint, and/or a muscle of substantially normal function in proximity of the joint.06-24-2010
20100234906SYSTEM AND METHOD FOR CONTROLLING RATE-ADAPTIVE PACING BASED ON A CARDIAC FORCE-FREQUENCY RELATION DETECTED BY AN IMPLANTABLE MEDICAL DEVICE - Techniques are provided for use in controlling rate-adaptive pacing within implantable medical devices such as pacemakers or implantable cardioverter-defibrillators (ICDs). In one example, a force-frequency relationship is determined for the heart of the patient, which is representative of the relationship between cardiac stimulation frequency and myocardial contractile force. To this end, various parameters are detected for use as surrogates for contractile force, including selected systolic pressure parameters and cardiogenic impedance parameters. Rate-adaptive pacing is then controlled based on the detected force-frequency relationship to, for example, deactivate rate-adaptive pacing if the slope and/or abscissa of the force-frequency relationship indicates significant contractility dysfunction within the patient. In other examples, rather than deactivating rate-adaptive pacing, control parameters are adjusted to render the rate-adaptive pacing less aggressive. In still other examples, trends in the slope and/or abscissa of the force-frequency relationship are monitored to detect contractility dysfunction and/or heart failure and titrate medications accordingly.09-16-2010
20100228304ELECTRICAL STIMULATION DEVICE WITH ADDITIONAL SENSORY MODALITIES - A therapeutic apparatus comprising an electrical stimulation delivery means, and at least one secondary modality delivery means, wherein the secondary modality delivery means is in an active state during at least a portion of a refractory period of the electrical stimulation delivery means.09-09-2010
20100234907Splanchnic Nerve Stimulation for Treatment of Obesity - A method for the treatment of obesity or other disorders by electrical activation or inhibition of the sympathetic nervous system is disclosed. This activation or inhibition can be accomplished by stimulating the greater splanchnic nerve or other portion of the sympathetic nervous system using an electrode. This nerve activation can result in reduced food intake and increased energy expenditure.09-16-2010
20100145398Cancer Treatment Equipment - A cancer treatment equipment includes a case (06-10-2010
20100222831ELECTRODE STRUCTURES AND METHODS FOR THEIR USE IN CARDIOVASCULAR REFLEX CONTROL - Devices, systems and methods are described by which the blood pressure, nervous system activity, and neurohormonal activity may be selectively and controllably reduced by activating baroreceptors. A baroreceptor activation device is positioned near a baroreceptor, preferably a baroreceptor located in the carotid sinus. A control system may be used to modulate the baroreceptor activation device. The control system may utilize an algorithm defining a stimulus regimen which promotes long term efficacy and reduces power requirements/consumption. The baroreceptor activation device may utilize electrodes to activate the baroreceptors. The electrodes may be adapted for connection to the carotid arteries at or near the carotid sinus, and may be designed to minimize extraneous tissue stimulation.09-02-2010
20100121391METHOD AND APPARATUS FOR DELIVERING CHRONIC AND POST-ISCHEMIA CARDIAC THERAPIES - An implantable cardiac rhythm management (CRM) device delivers a chronic therapy while detecting an ischemic state. When the ischemic state indicates the occurrence of an ischemic event, the implantable CRM device delivers a post-ischemia therapy. The post-ischemia therapy and the chronic therapy are adjusted using feedback control with the ischemic state and parameters indicative of the effectiveness of the post-ischemic therapy and the effectiveness of the chronic therapy as inputs.05-13-2010
20100114190NERVE STIMULATOR AND METHOD USING SIMULTANEOUS ELECTRICAL AND OPTICAL SIGNALS - An apparatus and method for stimulating animal tissue (for example to trigger a nerve action potential (NAP) signal in a human patient) by application of both electrical and optical signals for treatment and diagnosis purposes. The application of an electrical signal before or simultaneously to the application of a NAP-triggering optical signal allows the use of a lower amount of optical power or energy than would otherwise be needed if an optical signal alone was used for the same purpose and effectiveness. The application of the electrical signal may precondition the nerve tissue such that a lower-power optical signal can be used to trigger the desired NAP, which otherwise would take a higher-power optical signal were the electric signal not applied. Some embodiments include an implanted nerve interface having a plurality of closely spaced electrodes placed transversely and/or longitudinally to the nerve and a plurality of optical emitters.05-06-2010
20100198281METHODS FOR TREATING DISORDERS OF PERCEPTUAL INTEGRATION BY BRAIN MODULATION - A method for brain modulation includes modulating a predetermined site in the brain in order to treat tinnitus and other phantom perceptions, including hallucinations and the perceived compulsion to take an action. Modulation may be performed electrically, chemically, in combination, or by other techniques. The method may involve surgically implanting a medical lead at a predetermined site, and coupling the lead to an electrical signal generator or source of drugs or other chemicals. Alternatively, a predetermined site may be modulated by means of noninvasive electrical modulation such as electromagnetic induction, or other means such as by creating lesions with methods such as heating, freezing, or radiation treatment, or by virus-mediated cell destruction or functional inactivation.08-05-2010
20100198280TRANSCEIVER DUTY CYCLED OPERATIONAL MODE - This disclosure describes an operational mode of a telemetry module. A device, such as a programming device, operating in accordance with the techniques of this disclosure determines that a transceiver of an implantable medical device is operating in a duty cycled operational mode that includes at least one interval during which the transceiver is powered down interleaved with intervals during which the transceiver is powered up, e.g., for transmitting or receiving communications over an established communication session. The programming device is configured to transmit information during the at least one interval in which the transceiver of the implantable medical device is powered down. Doing so ensures that the channel over which the programmer and implantable medical device communicate will not be usurped by another device.08-05-2010
20100198279TRANSCEIVER DUTY CYCLED OPERATIONAL MODE - A device, such as an IMD, operating in accordance with the techniques of this disclosure detects a telemetry configuration event and, in response to the telemetry configuration event, configures a telemetry module of the IMD to operate in a duty cycled operational mode. The duty cycled operational mode includes a plurality of intervals during which a transceiver of the telemetry module is powered down interleaved with intervals during which the transceiver is powered up, e.g., for transmitting or receiving communications over an established communication session. The power freed up during the intervals in which the transceiver is powered down may be allocated for use by other components of the IMD. The telemetry module maintains information regarding the established communication session during the plurality of intervals during which the transceiver is powered down such that transmit and receive operations may immediately begin during intervals in which the transceiver is powered up.08-05-2010
20090248099Systems and methods for improving memory in Alzheimer's patients - In many aspects, the invention relates to systems and methods for providing memory therapy by modulating neural firing rhythms, in particular in Alzheimer's patients. The stimulation of neurons is controlled through a feedback process whereby neuron firing rhythms are altered based on naturally occurring electrical and chemical activity in the brain. Neurons in the nucleus basalis and dentate gyrus may be targeted in order to establish neural signaling pathways and establish communication between these regions.10-01-2009
20090318983METHOD AND APPARATUS FOR DETECTION AND TREATMENT OF AUTONOMIC SYSTEM IMBALANCE - Method and apparatus for preventing autonomic system disturbances by recording physiological parameters, measuring beat-to-beat variability of these parameters, and using the measured beat-to-beat variability to control the delivery of drug therapy and electrical impulses to the heart.12-24-2009
20110130796Thermostimulation methods using multilayer pads with integrated temperature regulation - A therapeutic method. The inventive method includes the steps of: applying a pad to a patient having a biometric sensor adapted to feedback a signal; coupling said feedback signal to an inline control system; coupling said inline control system to a console; and regulating energy applied to said pad by the inline control system based on the output of said sensor coupled to said inline control system and an output of said console. In the illustrative embodiment, the therapeutic method is thermostimulation and includes the steps of applying heat and stimulation via the pad, sensing temperature at the pad with an embedded temperature sensor and regulating the heat current at the pad via the inline control system in response to the output of the temperature sensor. In an alternative embodiment, the embedded sensor is a galvanic skin response sensor for measuring skin conductivity and having output is used by the inline controller in the treatment of dermatological conditions, relaxation treatment, desensitization training or other purposes. In another embodiment, the embedded sensor is electromyography sensor for measuring muscular electrical activity for the treatment of patients for weakness, impaired muscle strength, or gait analysis. In yet another embodiment, the embedded sensor is a pulse sensor. In this case, the inline controller uses the data to measure the patient's heart rate. In any case, useful data with respect to the performance of and conditions at each pad is displayed either on the inline controller and/or at the console. In addition, the inline controllers may be adapted to communicate with each other and/or with other external devices.06-02-2011
20090187223PELTIER UNIDIRECTIONAL AND SELECTIVE NERVE STIMULATION - Apparatus is provided including an assembly (07-23-2009
20090112273SYSTEMS, METHODS AND DEVICES FOR A SKULL/BRAIN INTERFACE - A method is disclosed for conveying a form of neuromodulation (e.g., electrical, chemical, optical, or thermal) from an external neuromodulation source interiorly of the skull to modulate neural activity. The method involves forming one or more apertures through or partially through the skull to provide an interface for delivering the neuromodulation. A method is disclosed for sensing one or more parameters characteristic of one or more states of the brain through an interface formed with one or more apertures extending all the way or part of the way through the skull. A device is disclosed that is implantable in the skull of a human patient to provide an interface between the exterior of the skull and the brain that includes a channel of a length sufficient to traverse the entire thickness of the skull or at least a part of the thickness of the skull. The channels may be provided in a wide variety of shapes and sizes with or without inner lumens. The channels may be configured for ion conduction of electrical signals, enabling DC or near DC stimulation of target neurons. Methods and devices for transferring energy (e.g., thermal energy) generated inside the skull to the outside of the skull and vice versa are also disclosed.04-30-2009
20090069855METHOD AND APPARATUS FOR MINIMIZING POST-INFARCT VENTRICULAR REMODELING - A cardiac rhythm management device is configured to deliver pre-excitation pacing to one or more sites in proximity to an infarcted region of the ventricular myocardium. The pre-excitation pacing in conjunction with counterpulsation therapy serves to either prevent or minimize post-infarct remodeling.03-12-2009
20090069854Implantable electric device - An implantable electric device comprising: a deployable round structure initially in a cramped state and adapted to be expanded into a deployed state, with at least one of a plurality of coils provided about the structure; a power source; and an electric circuitry for generating alternating currents in said at least one of the plurality of coils to generate an alternating electromagnetic field within the structure. In some embodiments of the invention it serves as a motor, and in some embodiments it serves to enhance blood flow within a patient's vasculature.03-12-2009
20130144354COMBINED OPTICAL AND ELECTRICAL NEURAL STIMULATION - A neural-stimulating device for stimulating nerve cells of a recipient is provided. The neural-stimulating device comprises an electromagnetic radiation source configured to generate one or more optical stimulation signals and an electrical stimulation generator configured to generate electrical stimulation signals. The neural-stimulating device also comprises an implantable stimulating assembly configured to be implanted in the recipient, and having disposed thereon an optical contact to deliver the one or more optical stimulation signals to the nerve cells, and an electrical contact to deliver the electric stimulation signals to the nerve cells.06-06-2013
20110029031BIMODAL HEARING PROSTHESIS - A bimodal hearing prosthesis for rehabilitating the hearing of a recipient. The hearing prosthesis comprises: a sound processing unit configured to process a received sound signal; and an implantable bimodal stimulation system, comprising: a mechanical stimulation arrangement configured to generate waves of fluid motion in a recipient's inner ear fluid based on the processed sound signal; an electrode assembly configured to deliver electrical stimulation signals generated based on the processed sound signal to a recipient's cochlea.02-03-2011
20110009915APPARATUS AND METHOD FOR MOVEMENT OF ELECTRICITY OR FLUID INTO AND OUT OF THE BODY - An apparatus for communication between a site within a body deep to the skin and a source, depot, reservoir, device, machine, or power source external to the body via the mouth of the body, comprising an implant for placement in tooth-supporting bone, the implant having a first portion extending into the mouth external to the tooth-supporting bone, a second portion for being embedded in the tooth-supporting bone, and an opening extending along the implant from the first portion to the second portion; and a conduit for coupling to the second portion of the implant when the implant is implanted in the tooth-supporting bone so that the conduit is in communication with the opening, the conduit being for extending from the implant to the site in the body.01-13-2011
20110009914CONTROLLED TITRATION OF NEUROSTIMULATION THERAPY - Described herein are methods and devices that utilize electrical neural stimulation to treat heart failure by modulating a patient's autonomic balance in a manner that inhibits sympathetic activity and/or augments parasympathetic activity. Because other therapies for treating heart failure may also affect a patient's autonomic balance, a device for delivering neural stimulation is configured to appropriately titrate such therapy in either an open-loop or closed-loop fashion.01-13-2011
20110029030Methods and Compositions for Treating a Disease Condition in a Subject - Methods for treating a disease condition in a subject are provided. The subject methods are characterizing by enhancing at least one symptom of the disease condition in a manner effective to cause the subject to mount a compensatory response effective to treat the disease condition. Also provided are compositions, kits and systems for practicing the subject methods.02-03-2011
20110040344MYOCARDIAL INFARCTION TREATMENT SYSTEM WITH ELECTRONIC REPOSITIONING - Methods and devices for treating a blockage in the coronary arterial system are provided. Some blockages in the coronary arterial system restrict the blood flow to a portion of the heart, causing ischemia or infarction. Such blockages may be treated by displacing, removing and/or breaking up the blockage, which allows blood to reperfuse into the infarcted portion of the heart. Before, during, and/or after the reperfusion, cardioprotective pacing is provided to the heart. The devices have multiple electrodes in order to provide multiple locations at which the cardioprotective pacing may be delivered. The devices are adapted to deliver cardioprotective pacing to the heart via the electrode that results in a relatively high level of dyssynchrony of the heart.02-17-2011
20100262202ELECTRICAL STIMULATION UNIT AND WATERBATH SYSTEM - A method for treating an infected area on a subject, comprising the steps of: exposing the infected area to an aqueous solution; and providing direct current to the aqueous solution to treat the infected area.10-14-2010
20100057149DEVICE, SYSTEM, AND METHOD TO IMPROVE POWERED MUSCLE STIMULATION PERFORMANCE IN THE PRESENCE OF TISSUE EDEMA - The invention provides systems and methods for neuromuscular electrical stimulation to muscle tissue. Stimulation electrodes may be provided on a stimulation pad, configured to provide electrical stimulation to a target tissue. A system for neuromuscular electrical stimulation may also include pressure generating mechanisms that may provide a compressive force to a region with the target tissue, thereby removing some excess third space fluid from the region.03-04-2010
20100036446Methods for electrosurgical electrolysis - Methods for electrosurgical electrolysis for treating tissue within a body, including methods that operate in an electrolyzable medium, including an aqueous electrolyzable medium, by means of electrolysis, and optionally by means of oxy-hydrogen combustion for use in treatment, including therapeutic methods of electrolysis to effect advantageous tissue changes. 02-11-2010
20100131025Apparatus and method for treating diabetic neuropathy and peripheral vascular pathologies - The present invention is directed to an apparatus and method for treating a person afflicted with diabetic neuropathy, diabetically-associated wound, peripheral arterial disease (PAD), pain disorders, TMJ, shoulder, migraines, back pain, neck pain but not limited to the disorders mentioned. Can be any neurological disorder, circulatory disorder, lymphatic disorder, any disorder that can be helped by exercise and movement of muscle tissue and stimulation of nerves, improved lymphatic drainage, decreased edema, increased circulation. The apparatus comprises one or more cuffs constructed from straps or bands or embedded pads with cold laser diodes which can be secured about a limb or body part of a patient (e.g., leg and/or arm) and which are constructed with low intensity (cold laser) diodes for applying laser light and with electrical electrodes for applying electrical pulses, respectively, to the patient's limbs, torso, head, neck, arms, hands, feet at the locations of the cuffs or the embedded pads.05-27-2010
20090216288FEEDBACK METHOD FOR DEEP BRAIN STIMULATION WITH DETECTION OF GENERALIZED EFFERENCE COPY SIGNALS - Disclosed is a method for improving cognitive function or for improving coordination of function across a patient's cortical regions. The method includes applying electrical stimulation to at least a portion of the patient's subcortical structures involved in the generation and control of generalized efference copy signals. Internally generated movement of the patient is then detected and, in response to such internally generated movement, application of electrical stimulation is controlled. The method of the present invention has a number of benefits, including increasing flexibility in identifying targets for stimulation, improving the probability of successfully treating brain injury, and permitting patient biofeedback and self-regulation.08-27-2009
20100063556DEVICE FOR THE MEDICAL CARE OF A PATIENT IN AN EMERGENCY03-11-2010
20110077701METHOD AND APPARATUS FOR TISSUE PROTECTION AGAINST ISCHEMIA USING REMOTE CONDITIONING - A stimulation system delivers stimulation to protect an ischemic region of a body from tissue damage caused by ischemia. The stimulation is delivered to one or more stimulation sites remote from the ischemic region to elicit a physiological effect that protects the ischemic region from the tissue damage caused by ischemia. In one embodiment, the stimulation system delivers cardioprotective stimulation to one or more stimulation sites remote from the heart to protect the heart from injuries associated with cardiac ischemic events. In another embodiment, the stimulation system delivers remote conditioning stimulation to one or more stimulation sites in or on the heart to protect a non-cardiac region from injuries associated with non-cardiac ischemic events.03-31-2011
20120035675EXTERNAL DEFIBRILLATOR WITH ADAPTIVE CPR DURATION - A method and apparatus for a defibrillating system is disclosed that monitors the patient during treatment and then uses the information it gathers to adjust treatment protocols during treatment based on the patient's response. The protocols may include adaptive rhythm analysis intervals, adaptive CPR intervals, and adaptive shock stacks. A method of operating a defibrillator may include the steps of: obtaining a data set on at least one physiological parameter of a patient in a first data gathering interval; performing an analysis of the data set; and determining a time interval between the analysis of the first data set and a second data set, or the duration of a CPR interval, or the number of shocks in a shock stack, based on the result of the analysis of the data set.02-09-2012
20110077700ARTIFICIAL BODY PART INCLUDING BIO-MEDICAL UNITS - An artificial body part system includes an artificial body part and a bio-medical unit. The artificial body part includes a bio-medical mounting mechanism. The bio-medical unit is mechanically associated with the artificial body part based on the bio-medical mounting mechanism. The bio-medical unit includes a power harvesting module, a wireless communication module, and a functional module. The power harvesting module is operable to generate a supply voltage from a wireless source. The wireless communication module is operable to wirelessly communicate inbound data and outbound data. The functional module is operable to perform at least one function regarding the artificial body part, wherein the functional module performs the at least one function in response to the inbound data or to generate the outbound data.03-31-2011
20110060377MEDICAL CO-PROCESSOR FOR SIGNALING PATTERN DECODING AND MANIPULATION OF CELLULAR STRUCTURES - Devices, methods and systems for affecting living tissues (brain, spinal stem) by neuronal querying, decoding responses, determining signaling patterns for direct delivery of a range of signals to the neural tissue in order to induce specific cell behaviors through intrusive and non-intrusive methods.03-10-2011
20090018594METHODS AND DEVICES FOR MEDICAL TREATMENT - An endoluminal treatment device and method includes introducing an endoluminal device into a lumen of a patient and engaging a wall of the lumen with an implant device. The implant device can be a drug delivery device or medical device.01-15-2009
20120303077MEDICAL NEUROLOGICAL INSTRUMENT - The present invention relates to a medical neurological instrument which can be used to improve balance, comprising: (A) a control system for managing energy sources of different nature and (B) an emitter of said energy sources, wherein the emitter is configured to simultaneously apply the different types of energy to a patient by means of transducers, wherein the energies employed are: (i) light energy 18 with a wavelength of between 500 and 700 nm, (ii) light energy 19 with a wavelength of between 701 and 1050 nm, (iii) TENS Energy (Transcutaneous Electrical Nerve Stimulator) 20 with a maximum amplitude of 200V.11-29-2012
20120303076Systems and Methods of Powered Muscle Stimulation Using an Energy Guidance Field - NMES systems and methods for stimulating muscle tissue, and in some embodiments deep muscle tissue. The impedance near the surface of the skin is controllably increased to increase the percentage of energy delivered to a subject that stimulates muscle tissue.11-29-2012
20110029029IMPLANTABLE PACEMAKER DEVICE THAT USES IMPEDANCE CARDIOGRAPHY - An implantable pacemaker that uses impedance cardiography to measure intrathoracic impedance and then transmit impedance data to an external PC based analyzer for accurate calculation of cardiac output, and a method for optimizing cardiac resynchronization therapy using the pacemaker are disclosed.02-03-2011
20090292328Medical Device - A disposable medical device includes an electrode pad adapted to be placed in contact with a human or animal body and an electrical signal generator permanently attached to and in close proximity with the electrode pad and operable to generate an electrical signal, the signal generator having two output terminals, at least one of which is electrically operably connected to the electrode pad.11-26-2009
20080243199Electrical stimulus allergy treatment method - A method of reducing the symptoms of allergy including exposing the patient to the allergenic substance in containers and applying an electrical stimulus device to acupuncture meridian points on the patient's body to clear blockages in the flow of life-energy of the patient. The electrical signal acts as a carrier for the natural frequency of the allergen, exposing the patient to the natural frequency of the allergen, carried by the electrical signal.10-02-2008
20080215101SYSTEMS AND METHODS FOR TREATING MEDICAL CONDITIONS BY STIMULATION OF MEDIAL THALAMIC REGION - A system for treating medical conditions by neuromodulation of one or more target sites in the nervous system. In certain embodiments, at least one of the target sites is the medial thalamic region, including the intralaminar nucleus and the adjacent white and grey matter. In certain embodiments, where there is more than one target site, the other target sites is elsewhere in the nervous system, including the globus pallidus interna, subthalamic nucleus, corpus callosum, cerebellum, cerebral cortex (including the premotor cortex, motor cortex, and sensory cortex), ventral striatum, lateral thalamus, substantia nigra, and pedunculopontine nuclei. The medical conditions include movement disorders or improvement of movement function, stroke, neuropsychiatric or neuropsychologic disorders, neurodevelopmental disorders, and pain. Methods for treating medical conditions by neuromodulation of the intralaminar nuclei either alone or in combination with another target site(s) is also provided.09-04-2008
20110112591Waveguide neural interface device - A waveguide neural interface device including: a neural device implantable in tissue and including an array of electrode sites that electrically communicate with their surroundings, in which the array of electrode sites includes at least one recording electrode site; and a waveguide, coupled to the neural device, that carries light along a longitudinal axis and includes a light directing element that redirects the carried light from the waveguide to illuminate selectively targeted tissue, in which at least a portion of the redirected light is directed laterally away from the longitudinal axis and the recording electrode site is configured to sample illuminated tissue. A method for assembling a waveguide neural interface device is also described.05-12-2011
20130158612System and Method for Eyelid Simulation - A system and method of treating hyperactivity of an eyelid closing muscle in a subject after facial nerve paralysis includes providing a stimulation system and selectively stimulating eyelid opening muscle(s) or innervating nerves, eyelid opening reflexes, or eyelid opening reflexes in non-muscular tissue, using the stimulation system, without substantially activating the eyelid closing muscle. The system and method evokes eyelid movement in the subject.06-20-2013
20100292747TECHNIQUES FOR DELIVERY OF STEM CELL AND RELATED THERAPIES TO TREAT CARDIAC CONDITIONS - An exemplary method includes acquiring cardiac electrical activity information; detecting an R wave; and based on the detecting, calling for delivery of energy to cells located in a structure outside of the myocardium only during a period time within the QRS complex corresponding to the detected R wave. The energy delivered may be electrical stimulation energy or mechanical energy.11-18-2010
20100292746COMBINATION MEDICAL THERAPY DEVICE THAT INTEGRATES: ELECTRICAL STIMULATION, LIGHT THERAPY, HEAT, PRESSURE, AND VIBRATION. - A portable combination medical therapy device that integrates the collective beneficial characteristics of five separate and distinct therapeutic pain relieving, relaxing, stimulating and healing modalities. The device comprises an applicator head that contains: at least two electrically conducting electrodes, a vibration mechanism, light mechanism, heat mechanism and is functionally designed to enable the operator to apply varying pressure and movement to the tissue being treated. The beneficial healing, relaxing and pain relieving results are enhanced because of the convenience and synergistic effect that the portable multiple healing modalities provide.11-18-2010
20100292745METHOD AND APPARATUS FOR SAFETY CONTROL DURING CARDIAC PACING MODE TRANSITION - A cardiac pacing system introduces a transitional period when pacing mode changes, such as when pacing starts and stops, or when one or more pacing parameter values change substantially. For each pacing parameter that changes substantially when the pacing mode changes, its value is adjusted incrementally over the transitional period to protect the heart from potentially harmful conditions associated with an abrupt change in the value of that pacing parameter.11-18-2010
20110125205Thermostimulation system including multilayer pads with integrated temperature regulations - A thermostimulation system and method. The inventive thermostimulation system is adapted for use with a console for providing electrical currents for thermal and electrical stimulation in response to a first input from an operator via at least one electrical connector. Generally, the inventive thermostimulation system includes at least one inline control system coupled to the console via electrical connector for regulating the currents to an associated thermostimulation pad via a second connector. The pad has a temperature sensor adapted to provide a feedback signal to the inline control system. In more specific embodiments, plural pads and inline control systems are connected to the console. Each inline control system has a first microprocessor for providing heat and stimulation current control for the pad and a second microprocessor for providing overcurrent safety control for the pad. Each inline control system has a display and a patient over-temperature control switch. Each pad has a connector integrated multilayer construction with a heating element implemented with a wire matrix and slots for flexibility. In addition to a temperature sensor, each pad also includes two electrical stimulation contacts having a wire conductor along the length thereof. Each pad is connected to an associated inline control system via a flat connector. Specially designed strain relief grommets are provided on both ends of the flat cable.05-26-2011
20110125204Electrostimulation pad with integrated temperature sensor - A pad including a heating element and a temperature sensor operationally coupled to sense thermal energy within the pad in close proximity to the heating element. The temperature sensor is a film type resistance thermal detector. The pad includes at least one contact, preferably two contacts, in a parallel relation with the heating element for providing electrical stimulation. The heating element, the first and second electrical contacts and the sensor are encapsulated in a single unitary multilayer injection molded construction. The invention enables new thermal and thermostimulation methods and protocols by which the electrical stimulation and/or the heating current supplied to a thermo and/or thermostimulation pad are adjusted based on the temperature sensed by the pad per se.05-26-2011
20100305632TEMPERATURE ASSISTED STIMULATION - Various embodiments of an implantable system for delivering therapy comprise at least one of a heat sink or source to either reduce or increase temperature of excitable tissue, a pulse generator and at least one stimulation electrode to deliver electrical stimulation to excitable tissue, a memory and a controller. The memory has instructions for performing at least one stimulation routine and at least one thermal routine, and further has integration instructions for integrating the thermal routine(s) with the stimulation routine(s). The controller is configured to operate on the instructions to perform the stimulation routine(s) using the pulse generator and the at least one stimulation electrode, to perform the thermal routine(s) using the heat sink or the heat source, and to operate on the integration instructions to integrate thermal routine(s) with the stimulation routine(s).12-02-2010
20100305633Diagnostic And Therapeutic Chest Casing - A system and method is provided for detection, forewarning, and rapid therapeutic treatment of a patient's ischemic and arrhythmic heart condition, congestive heart failure, respiratory failure, etc. The system comprises a chest casing of a form fitting material. The inner surface of the chest casing comprises electrocardiogram sensor electrodes, auscultation sensors, impedance sensor electrodes, etc. The electrocardiogram sensor electrodes detect abnormal electrocardiogram signals. The auscultation sensors record internal sounds at predefined cardiac and respiratory auscultation sensor points. The impedance sensor electrodes measure thoracic impedance across two or more points on the chest wall. A control unit is connected to the sensors for collecting and processing patient information. The control unit transmits the processed patient information to an external monitoring station. The chest casing comprises therapeutic delivery points for delivering therapeutic electrical dosages and different therapies, for example, cooling therapy, to the patient via therapeutic devices connected on the chest casing.12-02-2010
20090171407METHOD AND APPARATUS FOR MINIMIZING POST-INFARCT VENTRICULAR REMODELING - A cardiac rhythm management device for in which pre-excitation pacing is applied to one or more sites in proximity to an infarcted region of the ventricular myocardium. Such pacing servers to either prevent or minimize post-infarct remodeling.07-02-2009
20090299418CONCURRENT BILATERAL SPG MODULATION - Apparatus (12-03-2009
20100280564MONITORING OF CHRONOBIOLOGICAL RHYTHMS FOR DISEASE AND DRUG MANAGEMENT USING ONE OR MORE IMPLANTABLE DEVICE - The health state of a subject is automatically evaluated or predicted using at least one implantable device. In varying examples, the health state is determined by sensing or receiving information about at least one physiological process having a circadian rhythm whose presence, absence, or baseline change is associated with impending disease, and comparing such rhythm to baseline circadian rhythm prediction criteria. Other chronobiological rhythms beside circadian may also be used. The baseline prediction criteria may be derived using one or more past physiological process observation of the subject or population of subjects in a non-disease health state. The prediction processing may be performed by the at least one implantable device or by an external device in communication with the implantable device. Systems and methods for invoking a therapy in response to the health state, such as to prevent or minimize the consequences of predicted impending heart failure, are also discussed.11-04-2010
20110202098METHODS AND APPARATUS FOR PULSED ELECTRIC FIELD NEUROMODULATION VIA AN INTRA-TO-EXTRAVASCULAR APPROACH - Methods and apparatus are provided for pulsed electric field neuromodulation via an intra-to-extravascular approach, e.g., to effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, changes in cytokine upregulation and other conditions in target neural fibers. In some embodiments, the ITEV PEF system comprises an intravascular catheter having one or more electrodes configured for intra-to-extravascular placement across a wall of patient's vessel into proximity with target neural fibers. With the electrode(s) passing from an intravascular position to an extravascular position prior to delivery of the PEF, a magnitude of applied voltage or energy delivered via the electrode(s) and necessary to achieve desired neuromodulation may be reduced relative to an intravascular PEF system having one or more electrodes positioned solely intravascularly. The methods and apparatus of the present invention may, for example, be used to modulate one or more target neural fibers that contribute to renal function.08-18-2011
20100030287METHODS FOR TREATING AUTISM - Methods of treating autism include applying at least one stimulus to a stimulation site within the brain of a patient with an implanted stimulator in accordance with one or more stimulation parameters. Systems for treating autism include a stimulator configured to apply at least one stimulus to a stimulation site within the brain of a patient in accordance with one or more stimulation parameters.02-04-2010
20100023071SYSTEMS AND DEVICES FOR NEURAL STIMULATION AND CONTROLLED DRUG DELIVERY - Medical devices and methods are provided for electrical stimulation of neural tissue and controlled drug delivery to a patient. The device includes an implantable drug delivery module which comprises a plurality of reservoirs, a release system comprising at least one drug contained in each of the reservoirs, and control means for selectively releasing a pharmaceutically effective amount of drug from each reservoir; a neural electrical stimulator which comprises a signal generator connected to at least one stimulation electrode for operable engagement with a neural tissue of the patient; and at least one microcontroller for controlling operational interaction of the drug delivery module and the neural electrical stimulator. The microcontroller may control the signal generator and the control means of the drug delivery module. The device may further include a sensor operable to deliver a signal to the microcontroller, for example to indicate when to deliver electrical stimulation, drug, or both.01-28-2010
20100016908Swallowing Air Pulse Therapy Mouthpiece and Method for the Use Thereof - An oral appliance for administering a stimulus, such as a substance, to the mouth of a user includes a flexible tube having an inlet portion, a first curved portion forming an ear loop connected to the inlet portion, a second curved portion forming a lip bend connected to the first curved portion, and an outlet portion extending from the second curved portion. Alternatively, a mouthpiece for delivering a substance to the mouth of a user includes a housing having an inlet portion, a riser portion extending upwardly from the inlet portion and a curved outlet portion. A flexible tube is coupled to the housing. A method of delivering a substance to a predetermined location in a user's mouth includes disposing a flexible tube between a row of teeth and an interior surface of a cheek. The flexible tube has an exit port positioned in a rear portion of the user's mouth. No portion of the flexible tube is disposed between the upper and lower teeth of the user such that the upper and lower teeth can be closed against each other. The method further includes dispensing a substance through the exit port.01-21-2010
20100268288ELECTRICAL DEVICES AND ANTI-SCARRING AGENTS - Electrical devices (e.g., cardiac rhythm management and neurostimulation devices) for contact with tissue are used in combination with an anti-scarring agent (e.g., a cell cycle inhibitor) in order to inhibit scarring that may otherwise occur when the devices are implanted within an animal.10-21-2010
20090299419Blood flow stimulation bandage - Flexible, form fitting, uniquely shaped, body part bandages incorporate flexible carbon fibre blood flow stimulation planar emitters to provide therapeutic blood flow stimulation. Emitters are electrically powered and radiate pulsed electro magnetic energy at an ideal wavelength—typically in the 0.8 micron to 15 micron range—and frequency—typically in the 0.5 Mhz to 5 MHz range or 20 Hz to 200 Hz range—to stimulate circulation in sub dermal tissue. The carbon fibre emitters provide the means to maximize and control surface coverage and through their planar design also provide very uniform energy emissions over the entire applied surface area.12-03-2009
20090216287STIMULATION METHOD FOR THE SPHENOPALATINE GANGLIA, SPHENOPALATINE NERVE, OR VIDIAN NERVE FOR TREATMENT OF MEDICAL CONDITIONS - A method is provided for surgically implanting a first electrode and a second electrode on or proximate to at least one of the sphenopalatine ganglia, the sphenopalatine nerves, or the vidian nerves located on different sides of a patient's face. One step of the method includes inserting the first electrode into a coronoid notch located on one side of the patient's face. A second electrode is inserted into a coronoid notch located on the other side of the patient's face. The first and second electrodes are then advanced on or proximate to first and second locations on different sides of the patient's face, respectively. Each of the first and second locations includes at least one of the sphenopalatine ganglia, the sphenopalatine nerves, or the vidian nerves.08-27-2009
20110098762ELECTRICAL STIMULATION OF THE SYMPATHETIC NERVE CHAIN - The present invention provides a method of affecting physiological disorders by stimulating a specific location along the sympathetic nerve chain. Preferably, the present invention provides a method of affecting a variety of physiological disorders or pathological conditions by placing an electrode adjacent to or in communication with at least one ganglion along the sympathetic nerve chain and stimulating the at least one ganglion until the physiological disorder or pathological condition has been affected.04-28-2011
20120041499Neurostimulator - Methods and devices for stimulating nerves are disclosed. In one embodiment adapted for stimulating excitable tissue, the invention includes drive circuitry, an acoustic transducer and a pair of electrodes.02-16-2012
20120041498SYSTEMS AND METHODS FOR ENHANCING OR AFFECTING NEURAL STIMULATION EFFICIENCY AND/OR EFFICACY - Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy are disclosed. In one embodiment, a system and/or method may apply electromagnetic stimulation to a patient's nervous system over a first time domain according to a first set of stimulation parameters, and over a second time domain according to a second set of stimulation parameters. The first and second time domains may be sequential, simultaneous, or nested. Stimulation parameters may vary in accordance with one or more types of duty cycle, amplitude, pulse repetition frequency, pulse width, spatiotemporal, and/or polarity variations. Stimulation may be applied at subthreshold, threshold, and/or suprathreshold levels in one or more periodic, aperiodic (e.g., chaotic), and/or pseudo-random manners. In some embodiments stimulation may comprise a burst pattern having an interburst frequency corresponding to an intrinsic brainwave frequency, and regular and/or varying intraburst stimulation parameters. Stimulation signals providing reduced power consumption with at least adequate symptomatic relief may be applied prior to moderate or significant power source depletion.02-16-2012
20120209341METHOD FOR THE TREATMENT OF GALLSTONES - There is provided a method for controlling the movement of bile and/or gall stones in the biliary duct. The method comprises gently constricting (i.e., without substantially hampering the blood circulation in the tissue wall) at least one portion of the tissue wall to influence the movement of bile and/or gallstones in the biliary duct, and stimulating the constricted wall portion to cause contraction of the wall portion to further influence the movement of bile and/or gallstones in the biliary duct. The method can be used for restricting or stopping the movement of bile and/or gallstones in the biliary duct, or for actively moving the fluid in the biliary duct, with a low risk of injuring the biliary duct.08-16-2012
20120046702APPARATUS FOR DELIVERY OF PHARMACEUTICALS TO THE COCHLEA - An implantable electrode array assembly configured to stimulate tissue of a recipient, including an elongate member configured to be inserted into a recipient, wherein at least a portion of the elongate member includes a bio-active substance.02-23-2012
20120016431VESTIBULAR STIMULATION SYSTEM - A vestibular stimulation system and method that includes a housing, a power supply disposed in the housing, an electrode assembly adapted to be coupled to the housing, and a controller disposed in the housing and operatively coupled to the power supply. The controller controls the delivery of energy from the power supply to the electrode assembly. An input element is also disposed on an exterior surface of the housing. The input element is manually manipulated to control the operation of the vestibular stimulation system. A display disposed on an exterior surface of the housing provides visual information regarding the operation of the vestibular stimulation system. A mounting assembly is coupled to the housing to mount the housing on such a user.01-19-2012
20120016430COGNITIVE FUNCTION WITHIN A HUMAN BRAIN - Methods and apparatus for improving cognitive function within a human. The invention utilizes an implanted device, such as an implantable signal generator or an implantable pump, to affect tissue elements within a Papez circuit of the human brain as well as tissue upstream or downstream from the Papez circuit. The implanted device delivers treatment therapy to thereby improve cognitive function by the human. A sensor may be used to detect various symptoms of the cognitive disorder. A microprocessor algorithm may then analyze the output from the sensor to regulate delivery of the stimulation and/or drug therapy.01-19-2012
20120022606CPR TIME INDICATOR FOR VENTILATIONS FOR A DEFIBRILLATOR DATA MANAGEMENT SYSTEM - A system is disclosed wherein patient data, such as an electrocardiogram (“ECG”) signal or a chest impedance measurement signal, collected by a defibrillator device during a resuscitation event is analyzed and processed by a computing device to provide an assessment of CPR administered during the event. The CPR assessment results in one or more CPR figures of merit that relate to temporal characteristics of the CPR relative to the duration of the event. In one embodiment, the CPR figure of merit represents a percentage of the event period during which chest compressions were administered to the patient.01-26-2012
20120059430Treatment and warning of recurring therapy and other events using an implantable device - An implantable neurostimulator system is capable of responsively treating epileptiform activity with electrical stimulation and other therapies and is further configured to detect periods of increased susceptibility to clinical seizures. The event densities of therapy applications (or detections or other events) in time are observed and calculated, and if high enough, measures are taken to warn the patient or provide additional therapy.03-08-2012
20110093026METHOD AND APPARATUS FOR CARDIORENAL ELECTRICAL STIMULATION - An implantable cardiorenal stimulator delivers cardiorenal stimulation in response to detection of decompensation associated with heart failure. The cardiorenal stimulation includes delivering renal stimulation pulses to promote diuresis and/or natriuresis and delivering cardiac stimulation pulses to enhance the diuretic and/or natriuretic effects of the renal stimulation pulses.04-21-2011
20120209340ELECTROKINETIC NERVE STIMULATOR - A device and method for stimulating nerves. In one application, the approaches treat nausea and vomiting caused by a reaction to general anesthesia. A bi-modal approach involving acustimulation and medicants is contemplated for specific conditions.08-16-2012
20100094366AIR/OXYGEN SUPPLY SYSTEM AND METHOD - Provided is a method that includes automatically providing air/oxygen at a pre-selected maximum pressure limit, breath volume and respiratory-rate. The pre-selected maximum pressure limit, breath volume, and respiratory-rate are automatically set as a function of a size of a mask coupled to an air/oxygen supply system. Further provided is a ventilator system that includes a ventilator mask, a ventilator supply system, and a mask conduit. The ventilator mask is configured in a size that will fit upon a selected range of sizes of human faces. The ventilator supply system includes an air/oxygen source and an air/oxygen regulator system configured to regulate air/oxygen flow parameters as a function of the size of the mask. The mask conduit is configured to couple the ventilator supply to the ventilator mask.04-15-2010
20100094365Method and system for responding to non-perfusing and non-shockable heart rhythms - A system and method are disclosed for prompting emergency medical personnel who are attending to a patient. When the patient presents a heart rhythm that is a non-perfusing and non-shockable rhythm or perfusing but unstable, the attending personnel are prompted to administer therapy, such as reestablishing perfusion by performing CPR. The attending personnel may also be urged to defer taking the pulse of the patient.04-15-2010
20090131995MICRODEVICE-BASED ELECTRODE ASSEMBLIES AND ASSOCIATED NEURAL STIMULATION SYSTEMS, DEVICES, AND METHODS - Microdevice-based electrode assemblies and associated neurostimulation systems, devices and methods are disclosed. A system in accordance with a particular embodiment includes a microdevice positioned to send signals or fluids to the patient, and/or to receive signals or fluids from the patient. The microdevice can include a housing having an external surface, and a signal/fluid transmitter/receiver positioned within the housing and coupled to a terminal carried by the housing. The system can further include a patient-implantable, flexible support member attached to the external surface of the housing and carrying the housing. The system can still further include an interface carried by the support member and connected to the terminal, with the interface being positioned to direct signals or fluids into patient tissue, and/or receive signals or fluids from the patient tissue.05-21-2009
20120130440AUTOMATIC DETERMINATION OF CHRONOTROPIC INCOMPETENCE USING ATRIAL PACING AT REST - An apparatus comprises an implantable cardiac signal sensing circuit that provides an electrical cardiac signal representative of cardiac activity of a subject, an implantable therapy circuit that delivers electrical pacing stimulation energy to a heart of a subject, and a controller circuit. The controller circuit includes a chronotropic incompetence detection circuit that initiates pacing of an atrium of the subject at a rate higher than a device-indicated rate or a sensed intrinsic rate, monitor the AV interval, initiates an increase in the pacing rate while continuing the monitoring of the AV interval, calculates a change in AV intervals between a highest paced rate used in the monitoring and a lowest paced rate used in the monitoring, and indicates that the AV intervals are evidence of chronotropic incompetence when the calculated change in the AV intervals exceeds a specified threshold AV interval change value.05-24-2012
20120165883SYSTEM AND METHOD FOR CORRELATION OF PATIENT HEALTH INFORMATION AND IMPLANT DEVICE DATA - A system and method for correlating health related data for display. The system includes a medical device recording data and a display producing device which correlates the data and simultaneously displays different types of data or displays two sets of the same type of data along with the circumstances at which the two sets of data were recorded. Such displays aid a physician in prescribing and ascertaining the efficacy of cardiac therapies.06-28-2012
20100174330NEURAL-STIMULATING DEVICE FOR GENERATING PSEUDOSPONTANEOUS NEURAL ACTIVITY - A neural-stimulating device for stimulating nerve cells of a recipient is provided. The neural-stimulating device comprises an electromagnetic radiation (EMR) generator configured to generate one or more optical stimulation signals configured to cause pseudospontaneous activity; and an implantable stimulating assembly having an optical contact coupled to the EMR generator, the stimulating assembly configured to be implanted in the recipient such that the one or more optical stimulation signals are applied to the nerve cells via the optical contact.07-08-2010
20100174329COMBINED OPTICAL AND ELECTRICAL NEURAL STIMULATION - A neural-stimulating device for stimulating nerve cells of a recipient is provided. The neural-stimulating device comprises an electromagnetic radiation source configured to generate one or more optical stimulation signals and an electrical stimulation generator configured to generate electrical stimulation signals. The neural-stimulating device also comprises an implantable stimulating assembly configured to be implanted in the recipient, and having disposed thereon an optical contact to deliver the one or more optical stimulation signals to the nerve cells, and an electrical contact to deliver the electric stimulation signals to the nerve cells.07-08-2010
20120172940Therapeutic Garment - Several embodiments are provided for a modular therapeutic garment having electrodes integral with the garment and treatment permitted by such garment. The therapeutic garment can comprise a compression knit fabric material, and an array of electrodes integral with the compression knit fabric material. The compression knit fabric material can exert pressures within a range including values suitable for clinical treatment. The array of electrodes can be arranged to overlie specific portions of a subject, such as muscle groups or other body parts. Each electrode of the array of electrode can be formed of a conductive knit fabric material. The conductive knit fabric material can enclose a liquid absorptive material. A method for treating a musculoskeletal dysfunction with the therapeutic garment also is provided. The method also can be effective at improving musculoskeletal condition of healthy subjects.07-05-2012
20100049264Diagnostic indicator and PSG interface for a closed loop neuromodulator - This document discusses, among other things, a system and method for providing diagnostic information from a closed loop neuromodulator, configured to provide sleep therapy for a patient, to a user or a polysomnograph (PSG). A first portion of the diagnostic information can be received at a diagnostic indicator register of the closed loop neuromodulator and an LED driver can be switched using the first portion of the diagnostic information. A second portion of the diagnostic information can be received at a PSG interface of the closed loop neuromodulator and provided to the PSG for display.02-25-2010
20100049263METHOD AND DEVICE FOR DETECTING AND TREATING DEPRESSION - A system is described for detecting and/or treating depression that may be incorporated into an implantable device such as a cardiac rhythm management device. The device may determine that depression is present by analysis of heart rate variability measured using the cardiac sensing channels of the device and/or by detection of blood-borne factors that are associated with depression. If depression is detected, the device may be configured to automatically delivery therapy such as neuromodulation and/or drug delivery.02-25-2010
20100049262METHOD OF TREATING A SEVERE DIABETIC ULCER - The present invention is directed to a specialized method of treating a severe diabetic ulcer that penetrates the subcutaneous fat layer of a patient. The method comprises the steps of: administering a treatment session to a diabetic patient having a severe diabetic ulcer, the treatment session comprising at least three pulsed electromagnetic fields (PEMF) applications, PEMF applications 1, 2, and 3, and at least two intermittent compression therapy (ICT) applications. The PEMF application and ICT therapy settings address specific factors that are necessary to induce healing of the diabetic ulcer and prevent amputation. In a preferred embodiment, the treatment session further comprises the step of applying a dressing having a silver and/or honey anti-infection composition thereon to the ulcer area to impede microbial growth in the ulcer area. In another embodiment, the method includes the step of applying ultrasound to the ulcer area for a time sufficient to inhibit microbial growth.02-25-2010
20100049265EMI/ESD hardened sensor interface for a closed loop neuromodulator - This document discusses, among other things, apparatus and mthiods for protecting an input and electronics of a closed loop neuromodulator. Electromagnetic interference (EMI) can be reduced using an EMI filter. Energy surges can be dissipated using a electrostatic discharge (ESD) device. An analog and a digital output can be produced using respiration information received at an input, each output indicative of resiration effort.02-25-2010
20100274305METHOD AND APPARATUS FOR ELECTRICALLY STIMULATING CELLS IMPLANTED IN THE NERVOUS SYSTEM - The following disclosure describes several methods and apparatus for stimulating cells implanted in the regions of nervous system, such as the brain, spinal cord or peripheral nerves. Accordingly, the functionality of the cells can be improved, for example, by differentiating undifferentiated or partially undifferentiated cells into neurons or other cells having action potentials. The method can also include promoting directional growth and connectivity of fully differentiated neural cells implanted in a patient's nervous system through electrical enhancement, for example, electrical stimulation via an anode and cathode. Methods in accordance with the invention can be used to treat brain damage (e.g., stroke, trauma, etc.), brain disease (e.g., Alzheimer's, Pick's, Parkinson's, etc.), and/or brain disorders (e.g., epilepsy, depression, etc.). The methods in accordance with the invention can also be used to enhance neural-function of normal, healthy brains (e.g., learning, memory, etc.), or to control sensory functions (e.g., pain).10-28-2010
20100274304METHOD AND DEVICE TO MANAGE FREEZING OF GAIT IN PATIENTS SUFFERING FROM A MOVEMENT DISORDER - The subject invention involves a device and method for treating patients with a movement disorder experiencing a sudden change in regularity of gait or akinesia, and comprising a device that detects the sudden change in regularity of gait or temporary akinesia and automatically issues a cue signal that restarts the movement.10-28-2010
20100298895SYSTEMS, METHODS, AND DEVICES USING STRETCHABLE OR FLEXIBLE ELECTRONICS FOR MEDICAL APPLICATIONS - System, devices and methods are presented that integrate stretchable or flexible circuitry, including arrays of active devices for enhanced sensing, diagnostic, and therapeutic capabilities. The invention enables conformal sensing contact with tissues of interest, such as the inner wall of a lumen, a nerve bundle, or the surface of the heart. Such direct, conformal contact increases accuracy of measurement and delivery of therapy.11-25-2010
20100274306METHOD AND APPARATUS FOR DEVICE CONTROLLED GENE EXPRESSION FOR CARDIAC PROTECTION - A gene regulatory system detects ischemia events and is capable of delivering a biologic therapy in response to the detection of an ischemic event or the reception of a command. The biologic therapy protects the heart from ischemic damage by regulating the expression of an exogenously introduced gene product. In one embodiment, the gene regulatory system includes an implantable system that emits at least one gene regulatory signal in response to the detection of the ischemic event or the reception of the command. The gene regulatory signal directly or indirectly regulates gene expression of the gene product.10-28-2010
20100274303Methods and Systems for Detecting Epileptic Events Using Nonlinear Analysis Parameters - Disclosed herein are methods, systems, and apparatus for detecting an epilepsy event in a patient using a medical device. The medical device is capable of determining an occurring epilepsy event, for example a seizure or an increased risk of a seizure. The determination is performed by determining at least one nonlinear analysis parameter associated with the beat sequence of the patient's heart. The medical device may then take a responsive action, such as warning, logging the time of the seizure, computing and storing one or more seizure severity indices, and treating the epilepsy event.10-28-2010
20100004707System and Method For Transducing, Sensing, or Affecting Vaginal or Body Conditions, and/or Stimulating Perineal Musculature and Nerves using 2-Way Wireless Communications - A system for sensing vaginal conditions or for affecting vaginal or body conditions in a mammal. The system includes a portable probe unit and a separate controller unit, both of which include two-way communication devices to both transmit signals to, and receive signals from, each other, wirelessly and in real time. The substantially smooth and sealed outer surface of the cylindrical body of the probe unit has a rounded end and is dimensioned to permit comfortable and repeated insertion into, removal from, and containment entirely within a mammal's vagina. The probe body has a device substantially flush with its outer surface and configured to deliver electrical pulses, receive electrical pulses, sense or sample vaginal conditions and/or deliver medication. Signals to the probe unit comprise control and programming signals acting as a feedback loop configured to start, stop and/or alter activity of the substantially flush device of the probe unit, either automatically or manually, for sensing vaginal conditions or for affecting vaginal or body conditions.01-07-2010
20110004261ELECTROMAGNETIC THERMAL THERAPY - A portable, non-invasive device for providing therapeutic treatment to a joint to promote healing of the joint includes a cuff positionable around the joint. The cuff includes an electromagnetic stimulator configured to provide an electromagnetic field within the joint and a single-use thermal exchange component configured to provide temperature-based therapy to the joint.01-06-2011
20110130797METHOD AND SYSTEM FOR DETECTING EPILEPTOGENESIS - Neuronal excitation and inhibition of the brain is tracked in the hippocampual CA1 network during a latent period, wherein biomarkers are observed which include a sustained increase in the firing rate of the excitatory postsynaptic field activity, paired with a subsequent decrease in the firing rate of the inhibitory postsynaptic field activity within the CA1 region of the hippocampus; the mean amplitude profiles of both fEPSP and fIPSP field potential activity during the latent period have characteristic shapes; both excitatory and inhibitory CA1 field activity firing rates are observed to follow a circadian rhythm that drifts during epileptogenesis; the circadian rhythms described are in-phase in controls and anti-phase during epileptogenesis; and the fEPSP rate drifts from a circadian rhythm to a greater extent than the fIPSP rate. An additional biomarker is a change in a circadian rhythm of core body temperature. Upon detection of one or more of the biomarkers in a patient with a predisposition to seizure, therapeutic measures including thermal, chemical, or electrical modulation are applied to prevent the occurrence of the seizure, in an open or closed loop process.06-02-2011
20120265262SYSTEM AND APPARATUS FOR EARLY DETECTION, PREVENTION, CONTAINMENT OR ABATEMENT OF SPREAD ABNORMAL BRAIN ACTIVITY - A method, comprising detecting an epileptic event in a neural network, wherein the event occurs in a first node; identifying a second node; and applying a therapy to the second node or any connection. A method, comprising determining a first body index indicative of epileptic activity; monitoring a second body index; detecting an indication of activity spread, based upon at least the second body index; and taking a responsive action, such as delivering therapy, modifying therapy, logging the indication, or warning. A method, comprising detecting an epileptic event in a first node of a neural network; applying a first therapy to a first neural structure for treating the event; and applying a second therapy to a second neural structure of the patient based on an event spread proclivity to a third neural structure. A non-transitive, computer-readable storage device for storing data that when executed by a processor, perform a method.10-18-2012
20110046687LIVE COMBINED STIMULATION OF AUDITORY, SENSORY AND MOTOR FUNCTIONS AND ENHANCED THERAPEUTIC AND COMMUNICATIVE APPLICATIONS BASED ON ADVANCED GENERATION OF COMPLEX ELECTRICAL SIGNALS - A stimulator device is disclosed that is capable to produce and apply synchronized complex electrical stimulation signals very responsive and user friendly with interactive ability to change and derivate multiple signals or processing parameters immediately and simultaneously. The stimulator processes signals e.g. music and is typically controlled in real-time by a communication protocol e.g MIDI data or live by a MIDI controller. Immediate patient response and adoption facilitates the development of more efficient, diversified and enjoyable stimulation content for the majority of therapies based on electrical activated transducers. Special scope is combined auditory, electrical and vibration stimulation of the sensory and motor functions. One disclosed embodiment is enhanced audio perception for deaf and hearing impaired patient. Another typical application is combined music, electrical and vibration stimulation e.g. for neck and back muscle relaxation or thrombosis prophylaxis provided by a PC based stimulation content generator and a protable player.02-24-2011
20120323288HYBRID CLUSTERED NEURAL INTERFACE SYSTEM - An apparatus comprises a flexible substrate. The flexible substrate includes a first substrate surface, a surface electrode array that includes a plurality of electrodes disposed on the first substrate surface, one or more flexible neural probes substantially orthogonal to the first substrate surface and insertable into biological tissue, and a penetrating electrode array that includes a plurality of electrodes formed on the one or more flexible neural probes, wherein electrodes of the surface electrode array and the penetrating electrode array are configured to one or both of receive a neural signal from a neural signal source and provide electrical stimulation energy to a neural stimulation target.12-20-2012
20090259266System for Heart monitoring, Characterization and Abnormality Detection - A system analyzes and characterizes cardiac electrophysiological signals by determining instantaneous signal entropy for identifying and characterizing cardiac disorders, differentiating cardiac arrhythmias, determining pathological severity and predicting life-threatening events. A system for heart monitoring, characterization and abnormality detection, includes an acquisition device for acquiring an electrophysiological signal representing a heart beat cycle of a patient heart. A signal processor derives an entropy representative value of the acquired electrophysiological signal within a time period comprising at least a portion of a heart beat cycle of the acquired electrophysiological signal and provides an entropy value as a function of the entropy representative value and the time period. A comparator generates data representing a message for communication to a destination device in response to the entropy value exceeding a predetermined threshold.10-15-2009
20110307023NEURAL MODULATION DEVICES AND METHODS - A system for designing a therapy or for treating a gastrointestinal disorder or a condition associated with excess weight in a subject comprising at least one electrode configured to be implanted within a body of the patient and placed at a vagus nerve, the electrode also configured to apply therapy to the vagus nerve upon application of a therapy cycle to the electrode; an implantable neuroregulator for placement in the body of the patient beneath the skin layer, the implantable neuroregulator being configured to generate a therapy cycle, wherein the therapy cycle comprises an on time during which an electrical signal is delivered, the electrical signal comprising: a) a set of pulses applied at a first selected frequency of about 150-10,000 Hz, wherein each pulse of the set of pulses has a pulse width of at least 0.01 milliseconds and less than the period of the first selected frequency.12-15-2011
20120101538DEVICES, SYSTEMS AND METHODS FOR EVALUATION AND FEEDBACK OF NEUROMODULATION TREATMENT - The present disclosure relates to devices, systems and methods for evaluating the success of a treatment applied to tissue in a patient, such as a radio frequency ablative treatment used to neuromodulate nerves associated with the renal artery. A system monitors parameters or values generated during the course of a treatment. Feedback provided to an operator is based on the monitored values and relates to an assessment of the likelihood that a completed treatment was technically successful. In other embodiments, parameters or values generated during the course of an incomplete treatment (such as due to high temperature or high impedance conditions) may be evaluated to provide additional instructions or feedback to an operator.04-26-2012
20100168806DEVICE AND METHOD FOR TREATING CARDIAC TISSUE OF A HEART OF A PATIENT WITH THERAPEUTIC LIGHT USING PHOTOBIOMODULATION - For treatment of cardiac tissue of a heart of a patient with therapeutic light using an implantable medical device connectable to at least one medical lead carrying electrodes and at least one fixation element that fixes the lead at a fixation area of the cardiac tissue, therapeutic light is emitted toward the at least one fixation area of cardiac tissue and/or toward a contact area between the at least one electrode and cardiac tissue using an intracorporeal light emitter.07-01-2010
20100131024ELECTROTHERAPY ORTHOPEDIC DEVICE - An electrotherapy orthopedic device including an electronic capsule and an orthopedic device, together providing a means to supply electrotherapy to damaged bones and tissue or promoting bone ingrowth to the device. A pre-programmed microprocessor delivers an optimal electrotherapy treatment regime, wherein a sequence of pulses form a plurality of waveforms available for specific clinical needs. A waveform, its pulse frequency, pulse width, duration and intensity (in sum, “Waveform Parameters”) are pre-programmed into the microprocessor based on the optimal treatment regimen for any particular disorder.05-27-2010
20120150245METHOD AND APPARATUS FOR RENAL NEUROMODULATION - A method is provided for renal neuromodulation. One step of the method includes providing an expandable support member having a cuff-like configuration and including a main body portion (MBP). The MBP includes a lumen for engaging a wall of a blood vessel including a portion of a renal vasculature. At least one electrode connected with the MBP is arranged to selectively deliver electric current to a desired location. An insulative material is attached to at least a portion of the MBP. Next, the MBP is implanted extravascularly so that the MBP is in direct contact with a portion of the renal vasculature. At least one electrode is positioned substantially adjacent a desired location where modulation of the sympathetic nervous system (SNS) is effective to alter renal function. Electric current is then delivered to the at least one electrode to effect a change in the SNS.06-14-2012
20120150244Integrated Resuscitation - A resuscitation system for resuscitating a patient, comprising at least two defibrillation electrodes adapted to be worn by the patient for extended periods of time, circuitry for monitoring the ECG of the patient, at least one processor configured for analyzing the ECG of the patient, and determining whether electrical therapy should be delivered to the electrodes, circuitry for providing defibrillation pulses to the defibrillation electrodes, and circuitry for providing resuscitation prompts, wherein at least the circuitry for monitoring the ECG, the processor configured for analysing the ECG, and the circuitry for providing resuscitation prompts are contained in one or more devices adapted to be worn by the patient.06-14-2012
20130018431METHOD FOR DIRECTED INTRANASAL ADMINISTRATION OF A COMPOSITION - Methods, kits, apparatus, and compositions for inhibiting a cerebral neurovascular disorder, a muscular headache, or cerebral inflammation in a human patient are provided. The methods comprise intranasally administering to the patient a pharmaceutical composition comprising a local anesthetic, and preferably a long-acting local anesthetic ingredient. A composition useful for practicing the methods of the invention is described which comprises at least one local anesthetic in a pharmaceutically acceptable carrier, wherein the composition is formulated for intranasal delivery. Cerebral neurovascular disorders include migraine and cluster headache. Muscular headaches include tension headaches and muscle contraction headaches. A kit comprising the composition and an intranasal applicator and a method of systemically delivering a pharmaceutically active agent to an animal are also included in the invention. Apparatus for directed intranasal administration of the compositions of the invention and for performing the methods of the invention are also described.01-17-2013
20110160781Method and Apparatus to Monitor Patients and Treat with Intraosseous Fluids - Automatic external defibrillator apparatus may be provided for use in cooperation with an intraosseous apparatus. Apparatus and methods may also be provided to execute protocols calling for external defibrillation and drug delivery. The disclosure provides a medical apparatus including two electrodes, a processor, a display, a driver, a drug delivery slot, a drug delivery port, and a voltage source. The two electrodes may include an attachment operable to releasably connect the two electrodes to the patient. The processor may be operable to collect and analyze a rhythm associated with the patient's heart from the two electrodes. The display may be operable to communicate instructions to a user. The driver may be operable to insert an intraosseous device into a bone and associated bone marrow of the patient. The drug delivery slot may be operable to receive a drug. The drug delivery port may be operable to communicate the drug from the drug delivery slot to the patient via the intraosseous device. The voltage source may be operable to deliver an electric shock to the patient via the two electrodes.06-30-2011
20080221630TREATING CANCER USING ELECTROMAGNETIC FIELDS IN COMBINATION WITH PHOTODYNAMIC THERAPY - A light generating circuit is implanted in a subject's body and aimed at a target region such as a tumor. A photosensitizer is introduced into the target region, and an AC electric field is induced in the region. The field causes the light generating circuit to generate light, which activates the photosensitizer; and at certain field strengths and frequencies, the field itself has a beneficial effect. The beneficial effects of the field and the activated photosensitizer are thereby obtained simultaneously.09-11-2008
20120253417DIFFERENTIAL NEUROSTIMULATION THERAPY DRIVEN BY PHYSIOLOGICAL THERAPY - An implantable neurostimulator system adapted to provide therapy for various neurological disorders is capable of varying therapy delivery strategies based on the context, physiological or otherwise, into which the therapy is to be delivered. Responsive and scheduled therapies can be varied depending on various sensor measurements, calculations, inferences, and device states (including elapsed times and times of day) to deliver an appropriate course of therapy under the circumstances.10-04-2012
20120253416SYSTEM AND METHOD FOR FRACTIONAL TREATMENT OF SKIN - A system and method for treatment of skin including a treatment surface having numerous small energy emitting points for fractional skin treatment as well as negative pressure outlets. During a treatment, negative pressure from the outlets may exert a pulling force on an opposing tissue surface to bring the tissue into contact with the energy points.10-04-2012
20130090700ELECTRODE STRUCTURES AND METHODS FOR THEIR USE IN CARDIOVASCULAR REFLEX CONTROL - Devices, systems and methods are described by which the blood pressure, nervous system activity, and neurohormonal activity may be selectively and controllably reduced by activating baroreceptors. A baroreceptor activation device is positioned near a baroreceptor, preferably a baroreceptor located in the carotid sinus. A control system may be used to modulate the baroreceptor activation device. The control system may utilize an algorithm defining a stimulus regimen which promotes long term efficacy and reduces power requirements/consumption. The baroreceptor activation device may utilize electrodes to activate the baroreceptors. The electrodes may be adapted for connection to the carotid arteries at or near the carotid sinus, and may be designed to minimize extraneous tissue stimulation.04-11-2013
20110313482SYSTEMS AND METHODS FOR ENHANCED VENOUS RETURN FLOW DURING CARDIAC EVENT - Systems and methods of enhancing cardiopulmonary circulation in a subject during resuscitation are provided. A signal is received responsive to an induced heart compression that is applied to the subject, for example during ventricular fibrillation, an asystolic condition, or cardiac arrest. Responsive to receipt of the signal, a muscle distal subject's heart is electrically stimulated to contract and expel blood into the venous blood flow toward a heart of the subject.12-22-2011
20110313481NOSE STIMULATOR FOR PRODUCING A STIMULATION SIGNAL TO A NOSE - An electronic stimulation system has ?a casing (12-22-2011
20110313480CARDIOVERTOR/DEFIBRILLATOR - Cardiovertor/defibrillator with electronics (12-22-2011
20130131743Endovascular Nerve Monitoring Devices and Associated Systems and Methods - Endovascular nerve monitoring devices and associated systems and methods are disclosed herein. A nerve monitoring system configured in accordance with a particular embodiment of the present technology can include a shaft having a proximal portion and a distal portion and a nerve monitoring assembly at the distal portion. The shaft is configured to locate the distal portion intravascularly at a treatment site. The nerve monitoring assembly can include a bipolar stimulation electrode array and a bipolar recording electrode array disposed distal to the bipolar stimulation electrode assembly.05-23-2013
20130144353Method for treating neurological /psychiatric disorders with stimulation to the subcaudate area of the brain - A method for treating a patient with a neurological or psychiatric disorder, comprising applying stimulation to at least a portion of the patient's subcaudate white matter of the subcaudate area under conditions effective to provide the patient with at least a partial relief from the neurological or psychiatric disorder. The stimulation may be electrical and/or pharmacological.06-06-2013
20080200959System and method to deliver therapy in presence of another therapy - Various aspects relate to a method. In various embodiments, a therapy of a first therapy type is delivered, and it is identified whether a therapy of a second therapy type is present to affect the therapy of the first therapy type. Delivery of the therapy is controlled based on the presence of the therapy of the second therapy type. Some embodiments deliver the therapy of the first type using one set of parameters in the presence of a therapy of a second type, and deliver the therapy of the first type using another set of parameters when the therapy of the second type is not present. In various embodiments, one of the therapy types includes a cardiac rhythm management therapy, and the other includes a neural stimulation therapy. Other aspects and embodiments are provided herein.08-21-2008
20100286736TECHNIQUES FOR DELIVERY OF STEM CELL AND RELATED THERAPIES TO TREAT CARDIAC CONDITIONS - An exemplary method includes acquiring cardiac electrical activity information, detecting a T wave and, based on the detecting, calling for delivery of matter to the heart where the matter may include one or more of stem cells, progenitor cells, nutrients and drugs. Another exemplary method includes calling for delivery of electrical energy to cells destined for implantation in the body or cells already implanted in the body. Such delivery may be timed according to cardiac electrical activity and/or delivered at an energy level below a capture threshold of neighboring tissue. Various other exemplary technologies are also disclosed.11-11-2010
20100286735Uterine Electrical Stimulation System and Method - Some embodiments of the invention provide a system and method for treating insufficient uterine contractions after labor and delivery. The system includes a control module and a current source controlled by the control module to produce stimulating current at a frequency greater than or equal to about 5.0 Hertz. The system also includes one or more stimulation electrodes to provide the stimulating current to the patient in order for the patient to produce tonic uterine contractions.11-11-2010
20130150908Pacemaker for Spasmodic Dysphonia - A stimulation system and method for treating to a human subject having spasmodic dysphonia includes a sensing electrode configured to detect voice activity of a vocalizing muscle of the subject and to generate a first signal, and a processor configured to receive the first signal from the sensing electrode and to generate at least one stimulation parameter based on the first signal. The system further includes a mechanical actuator configured to receive the stimulation parameter from the processor and to activate a glottic closure reflex of the subject in response to the stimulation parameter and a stimulating electrode configured to receive the stimulation parameter from the processor and stimulate the recurrent laryngeal nerve or the vagus nerve of the subject based on the stimulation parameter.06-13-2013
20090248098DEVICE FOR STIMULATION BY MEANS OF ELECTRIC AND MAGNETIC FIELDS, AND FIELD APPLICATORS FOR THIS PURPOSE - A device for stimulation via special electric and magnetic fields and optimized field applicators is provided. Derived from human physiology, the autonomic/vegetative nervous system, specifically its sympathetic and parasympathetic components, can be controlled by signals in the frequency ranges of 0.05 to 0.15 Hz and of 0.15 to 0.30 Hz, respectively. Along with other components, these constitute integral parts of corresponding modular physical cardiovascular stimulation programs. By addition of characteristic sinusoidal oscillations, including a positive or negative electric field between the head area and a peripheral area of a human or animal, with the corresponding low-frequency sympathetic or parasympathetic control frequency as base oscillation and with application-typical EEG frequencies and higher-frequency sinusoidal oscillations in the range of ca. 250 to 1500 Hz, characteristic stimulation programs can be established in modular configuration. The introduction of the information parameters for the sympathetic and parasympathetic components, via physical stimulation in the area of the spinal cord, the principal part of the central nervous system, is effected by the field applicators being embodied such that, in the upper body area, a concentration of the magnetic flux, which is generated by a mat applicator, is established in the center of the body, and, likewise on the basis of the physiological relationships in the lower half of the body, the associated mat applicator system is embodied such that the field energy is distributed to both leg areas, and two field strength maxima are thus obtained. To allow the advantage of stimulation via the electric potentials to be combined with the input of the magnetic field effects, a field applicator is equipped with a combination of a magnetic-field-generating coil arrangement and of an electrode arrangement generating the electric field. The electrode generating the electric field can at the same time be designed as a magnetic-field-generating coil.10-01-2009
20120022605SYSTEM FOR NERVE STIMULATION AND CARDIAC SENSING PRIOR TO AND DURING A MEDICAL PROCEDURE - A system for performing a cardiac medical procedure can included a cardiac medical device, a steerable catheter device, a cardiac stimulator, and a controller. The cardiac stimulator can be configured to adjust beating of a heart by electrically stimulating the heart. The controller can be configured to control electrical stimulation provided by the cardiac stimulator to adjust the beating of the heart to a first condition and to adjust the beating of the heart to a second condition.01-26-2012
20120029584PULSE DETECTION APPARATUS, SOFTWARE, AND METHODS USING PATIENT PHYSIOLOGICAL SIGNALS - The presence of a cardiac pulse in a patient is determined by evaluating physiological signals in the patient. In one embodiment, a medical device evaluates two or more different physiological signals, such as phonocardiogram (PCG) signals, electrocardiogram (ECG) signals, patient impedance signals, piezoelectric signals, and accelerometer signals for features indicative of the presence of a cardiac pulse. Using these features, the medical device determines whether a cardiac pulse is present in the patient. The medical device may also be configured to report whether the patient is in a VF, VT, asystole, or PEA condition, in addition to being in a pulseless condition, and prompt different therapies, such as chest compressions, rescue breathing, defibrillation, and PEA-specific electrotherapy, depending on the analysis of the physiological signals. Auto-capture of a cardiac pulse using pacing stimuli is further provided.02-02-2012
20120029583PULSE DETECTION APPARATUS, SOFTWARE, AND METHODS USING PATIENT PHYSIOLOGICAL SIGNALS - The presence of a cardiac pulse in a patient is determined by evaluating physiological signals in the patient. In one embodiment, a medical device evaluates two or more different physiological signals, such as phonocardiogram (PCG) signals, electrocardiogram (ECG) signals, patient impedance signals, piezoelectric signals, and accelerometer signals for features indicative of the presence of a cardiac pulse. Using these features, the medical device determines whether a cardiac pulse is present in the patient. The medical device may also be configured to report whether the patient is in a VF, VT, asystole, or PEA condition, in addition to being in a pulseless condition, and prompt different therapies, such as chest compressions, rescue breathing, defibrillation, and PEA-specific electrotherapy, depending on the analysis of the physiological signals. Auto-capture of a cardiac pulse using pacing stimuli is further provided.02-02-2012
20090264944Nerve Stimulator With Suction Capability - A device for use in a removing fluids and debris from a surgical wound and for location of nerves adjacent to the surgical wound comprises a hollow electrically conductive tube which has a lumen extending from the distal end thereof to the proximal end thereof. Openings are located at the distal end of the tube for suction removal of the fluid and debris. A handle located at the proximal end of the tube is provided for attachment of a second tube which is connected to a vacuum source. Also extending from or located within the handle is attachment means for connecting the conductive tube to an electrical nerve stimulation module. An electrically conductive ball is attached at the distal end of the conductive tube and distal to the openings in the tube. The openings are sized so that at least one dimension thereof is less then the diameter of the lumen to prevent the lumen from becoming clogged with debris having a size greater then the diameter of the lumen which is removed from the surgical wound.10-22-2009

Patent applications in class Combined with nonelectrical therapy