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With body soluble, antibactericidal or lubricating materials on conduit

Subclass of:

604 - Surgery

604019000 - MEANS FOR INTRODUCING OR REMOVING MATERIAL FROM BODY FOR THERAPEUTIC PURPOSES (E.G., MEDICATING, IRRIGATING, ASPIRATING, ETC.)

604048000 - Treating material introduced into or removed from body orifice, or inserted or removed subcutaneously other than by diffusing through skin

604930010 - Material introduced or removed through conduit, holder, or implantable reservoir inserted in body

604264000 - Body inserted tubular conduit structure (e.g., needles, cannulas, nozzles, trocars, catheters, etc.)

Patent class list (only not empty are listed)

Deeper subclasses:

Class / Patent application numberDescriptionNumber of patent applications / Date published
604265000 With body soluble, antibactericidal or lubricating materials on conduit 88
20100145286LAYERED NON-FOULING, ANTIMICROBIAL ANTITHROMBOGENIC COATINGS - Substrates, optionally coated with an undercoating, having grafted thereto one or more non-fouling materials are described herein. The non-fouling, polymeric material can be grafted to a variety of functionalized substrate materials, particularly polymeric substrates and/or polymeric undercoatings immobilized on a substrate. The compositions described herein are highly resistant protein absorption, particularly in complex media and retain a high degree of non-fouling activity over long periods of time. The compositions described herein may also demonstrate antimicrobial and/or anti-thrombogenic activity. The non-fouling material can be grafted to a functionalized substrate, or optionally from an undercoating on the substrate, preferably without significantly affecting the mechanical and/or physical properties of the substrate material06-10-2010
20090171302ENHANCED DURABILITY OF HYDROPHILIC COATINGS - Lubricous coatings, methods for making an using lubricous coatings, and medical device that include lubricious coatings. An example lubricous coating may include includes a hydrophilic polymer, a flow modifier, an acrylic monomer, a photoinitiator, and a solvent. The coating can be used to coat a medical device along an inner surface, an outer surface, or an intermediate surface.07-02-2009
20100106102APPARATUS FOR DELIVERY OF DEVICE AND ANTIMICROBIAL AGENT INTO TRANS-DERMAL CATHETER - An apparatus for delivery of an elongate member into the lumen of a trans-dermal catheter. In a preferred embodiment, the apparatus comprises a protective sheath configured to at least substantially surround an elongate member; and slidable member configured to travel along the protective sheath, the slidable member operatively coupled to the elongate member; wherein the elongate member is insertable into a lumen of a trans-dermal catheter by moving the slidable member along at least a part of the length of the protective sheath. In another embodiment, the apparatus comprises a protective sheath configured to at least substantially surround an elongate member; a slidable member configured to travel along the protective sheath, the slidable member operatively coupled to the elongate member; and a connecting member positioned on the distal end of the protective sheath, the connecting member configured to lock onto the distal end of a trans-dermal catheter; wherein the elongate member is insertable into the lumen of the trans-dermal catheter by moving the slidable member along at least a part of the length of the protective sheath.04-29-2010
20100106103DEVICE FOR DELIVERY OF ANTIMICROBIAL AGENT INTO TRANS-DERMAL CATHETER - A system for delivering an antimicrobial agent into the lumen of a trans-dermal catheter. In an embodiment, the system comprises an elongate member configured for insertion into a lumen of a catheter; an expandable portion of the elongate member, said expandable portion configured to increase in diameter upon exposure to an aqueous fluid; and an antimicrobial composition positioned to be delivered into the catheter. In another embodiment, the system comprises an elongate member configured for insertion into a lumen of a trans-dermal catheter, said elongate member comprising a hydrogel; and an antimicrobial composition positioned to be delivered into the catheter; wherein the elongate member defines a volume of liquid that is at least substantially contained within the lumen of the trans-dermal catheter.04-29-2010
20090124984Medical Appliance and Process for Producing the Appliance - A medical appliance having a metal surface in which a hydrophilic organic compound having a polar group is directly fixed to the metal surface in accordance with an electrochemical reaction without intermediate layers; and a process for producing a medical appliance which comprises dipping a material for a medical appliance having a metal surface and an electrode into a solution comprising a hydrophilic organic compound having a polar group, and fixing the hydrophilic organic compound to the metal surface of the material for a medical appliance in accordance with an electrochemical reaction by applying a voltage between a cathode and an anode using the material for a medical appliance as the cathode and the electrode as the anode. The medical appliance exhibits excellent lubricating property since the metal surface is tightly coated with a thin layer of the hydrophilic organic compound. Therefore, excellent operability is exhibited in insertion into blood vessels, and the possibility of causing damages on inner layers of blood vessels is small. The medical appliance can be produced in simple steps in accordance with the process.05-14-2009
20100069854Elastomeric Devices Containing Chlorhexidine/Fatty Acid Salts Made From Fatty Acids of 12 to 18 Carbons - In a medical device, an antimicrobial agent is combined with an elastomeric polymer material. The antimicrobial agent includes at least one chlorhexidine/fatty acid salt which is a neutralization product of chlorhexidine base and a fatty acid having between 12 and 18 carbon atoms.03-18-2010
20090306605Medical Treatment Device and Method for Manufacturing the Same - To provide a medical treatment device wherein the antithrombotic property and lubricity of a coating formed on the surface can be maintained in a stable state for a long period and also to provide a method for manufacturing the same. A mixture solution for coating wherein a copolymer of methyl vinyl ether with maleic acid anhydride, a quaternary ammonium salt and a polyether block amide dissolved in an organic solvent are applied upon the surface of a substrate comprising synthetic resin to form a coating and then urokinase and heparin are impregnated in the coating of the medical treatment device. The synthetic resin comprising the substrate is polyurethane, polyvinyl chloride, nylon or nylon elastomer. The quaternary ammonium salt is tridodecylmethylammonium chloride. An alkaline treatment is applied to a predetermined part of a substrate upon which a coating has been formed by application of the mixture solution.12-10-2009
20130060206SPIRAL THROMBECTOMY CATHETER - The subject matter relates a catheter having a helical or spiral tip defining an aspiration port for removing obstructions from blood vessels.03-07-2013
20130165871METHOD AND APPARATUS FOR INCREASING BLOOD FLOW THROUGH AN OBSTRUCTED BLOOD VESSEL - A method of increasing blood flow through an obstructed blood vessel includes providing an expandable member substantially made of a mesh having a plurality of interstices. The expandable member is inserted into the blood vessel, positioned within the blood vessel with the proximal member end upstream of the distal member end and the member body located radially adjacent at least a portion of an obstruction, and expanded to bring at least a portion of the member body into contact with the obstruction. An outward radial force is exerted on the obstruction to dislodge at least one fragment from the obstruction and to enhance blood flow through the blood vessel past the obstruction. The at least one fragment is passed through at least one interstice of the member body in the radial direction, and is selectively retained within the expandable member.06-27-2013
20090012481High Flow Rate Dialysis Catheters and Related Methods - High flow rate catheters, and related methods, are useful in dialysis and other procedures. A catheter according to the invention comprises a hub and a generally elongated conduit. The conduit has a substantially continuous and smooth wall. The conduit also defines at least one lumen and has a length extending from a proximal end to a distal end of the conduit. The proximal end is coupled to a hub and the distal end has an opening in communication with the lumen. The conduit has a conical shape which tapers along the length.01-08-2009
20100087789APPARATUS AND METHODS FOR MAKING COATED LINERS AND TUBULAR DEVICES INCLUDING SUCH LINERS - A medical device includes a proximal end, a distal end sized for introduction into a body lumen, and a lumen extending between the proximal and distal ends. The tubular device includes an inner liner including a coating on an inner surface thereof, a reinforcing layer surrounding at least a portion of the liner; and an outer layer surrounding the reinforcing layer and inner liner. The liner and outer layer may include multiple sections having different properties than one another, adjacent sections attached together by seams, which may be offset from one another. Apparatus and methods for making tubular devices with coated liners are also provided.04-08-2010
20100049146COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS - The application discloses a method for the preparation (by extruding, injection moulding or powder coating and subsequent cross-linking by irradiation with UV or visible light) of a medical device element involving a coating composition comprising: a) as the only polymer constituent(s), at least 50% by weight of poly(ethylene oxide)(s) optionally in combination with non-thermoplastic hydrophilic polymer(s), and b) low molecular weight scaffold(s) having a plurality of photo-initiator moieties covalently linked thereto and/or covalently incorporated therein, wherein the photo-initiator moieties constitute 0.01-20% by weight of the combined amount of the poly(ethylene oxide)(s), any non-thermoplastic hydrophilic polymers and the low molecular weight scaffolds. The application further discloses such extruded, injection moulded or powder coated medical devices having thereon a layer of a covalently cross-linked coating composition of a poly(ethylene oxide) (PEO), optionally a non-thermoplastic hydrophilic polymer and a low molecular weight scaffold having a plurality of residues of photo-initiator moieties.02-25-2010
20110301553Antimicrobial lubricant - An antimicrobial lubricant combines an antimicrobial agent, preferably silver based, with a silicone lubricant. This is achieved by first formulating a lubricant solution that has a non-volatile silicone lubricant and a volatile solvent carrier. An antimicrobial agent is added to the lubricant solution. The solution is then subjected to ultrasonic energy so that the antimicrobial agent is uniformly mixed with the lubricant in the solution. The solution containing the antimicrobial lubricant may be sprayed onto a medical device, for example the outer surface of the catheter of a peripheral IV catheter. After the solvent flashes off, a coat of uniform antimicrobial lubricant is formed on the catheter surface. The antimicrobial lubricant coating facilitates the insertion of the catheter to a patient, and at the same time prevents the growth of microorganisms from the device and infection to the patient.12-08-2011
20110288498ANTIMICROBIAL MATERIAL AND METHOD FOR MAKING THE SAME - This invention provides a modified catheter biomaterial that provides both immediate, and long-term microbiocidal effects on otherwise antibiotic-resistant strains of microorganisms. The material, which exhibits good mechanical performance characteristics for medical devices, is composed of a hydrophobic polyurethane (PU), a hydrophilic polyethylene vinyl acetate (PEVA), a soluble silver salt and a sparsely-soluble silver salt. The hydrophobic polyurethane provides the good physical properties, the PEVA the hydrophilicity necessary to allow some water ingress into the catheter, the soluble silver salt for an immediate burst effect, and the sparsely-soluble silver salt for sustained-release over many months postimplantation.11-24-2011
20080306455Method For Reducing The Amount Of Migrateables Of Polymer Coatings - This invention relates to an improved process for obtaining a cross-linked polymer coating on a surface. The invention also relates to coatings obtainable by that process and objects coated therewith. The invention also relates to medical devices comprising a coating, in particular to coils coated with an improved lubricious coating.12-11-2008
20090099533VIRUS DERIVED ANTIMICROBIAL PEPTIDES - Described herein are peptides having antimicrobial activity (antimicrobial peptides). The antimicrobial peptides, designated LBU, WLBU and WR, are analogs of the Lentivirus Lytic Peptide 1 (LLP1) amino acid sequence. The antimicrobial peptides are monomers or multimers of peptides referred to as the Lytic Base Unit (LBU) peptides, derived from the LLP1 analogs and also having antimicrobial activity. Also described herein are using the peptides in a variety of contexts, including the treatment or prevention of infectious diseases. Methods of killing fungi, such as 04-16-2009
20090099531Packaging for selectivity lubricating part of a medical device - A medical device lubricating assembly for imparting a lubricious and/or antimicrobial liquid onto a medical device is provided. The medical device is surrounded by a pouch and the assembly includes a barrier for bifurcating the pouch into a wet compartment and a dry compartment. Lubricating fluid is stored in the wet compartment or is otherwise introduced into the wet compartment prior to removal of the medical device from the pouch. This assists in insertion and implantation of the device into a body cavity or opening.04-16-2009
20090137969Apparatus and method for sterilizing a tubular medical line port - A device for sterilizing a tubular medical line IV port. The device includes a cap having an open tubular cavity on a distal end which is dimensioned to receive the medical line port therein. A handle is provided on the proximal end of the device for grasping and manipulating the cap. An outer disinfectant-impregnated member is coaxially secured in the distal cavity and dimensioned for engaging and scrubbing exterior surfaces or threads of the tubular port when inserted into the cavity. An inner disinfectant-impregnated member may also be coaxially secured in the cavity to simultaneously scrub internal surfaces of the port.05-28-2009
20110264057CATHETERS WITH LUBRICIOUS LININGS AND METHODS FOR MAKING AND USING THEM - Apparatus and methods are provided for creating tubular devices, e.g., as components for catheters, sheaths, and or other devices sized for introduction into a patient. In one embodiment, a method is provided for making a tubular device using a sheet of material including a coated first surface. The sheet is rolled around a mandrel until longitudinal edges of the sheet are disposed near or adjacent one another, e.g., without attaching the longitudinal edges together. A tubular braid is positioned over the sheet-wrapped mandrel, one or more tubular segments are positioned over the tubular braid, and heat shrink tubing is positioned over the tubular segments. The resulting assembly is heated to cause the tubular segments to at least partially reflow and/or otherwise laminate the tubular segments to the tubular braid and sheet. The heat shrink tubing and mandrel are then removed to create the tubular device.10-27-2011
20100114042COATED MEDICAL DEVICE - The invention relates to an article comprising a coating, which coating comprises at least two layers, of which the inner layer is a primer layer, comprising a supporting network comprising a supporting polymer, and the outer layer is a functional layer comprising a multifunctional polymerizable compound.05-06-2010
20100268174COMBINATION OF ALCOHOL LOCK AND GENTIAN VIOLET CATHETER - Implantable catheters treated with gentian violet and methods for disinfecting the catheters with alcohol are provided.10-21-2010
20100082003COMPOSITIONS AND METHODS FOR COATING MEDICAL IMPLANTS - Medical implants are provided which release an anthracycline, fluoropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or reducing the incidence of infection associated with the implant.04-01-2010
20100100057POLYMER COATINGS WITH CATALYST FOR MEDICAL DEVICES - Coating compositions and coatings for medical devices formed from the coating compositions that include a catalyst in a support polymer, where the support polymer helps to support and retain the catalyst in the coating on the medical device. The catalyst in the support polymer can act to chemically bond specific compounds migrating from a body of the medical device formed from a polymer to at least one of the polymer and/or other specific compounds migrating from the body of the medical device.04-22-2010
20080228150Soft body catheter with low friction lumen - The disclosure is directed to radiation catheter devices, methods for controlled application of irradiation to tissue at a body site, such as a cavity formed after removal of tissue, e.g. cancer, using such radiation catheter devices, solutions for forming a more lubricious luminal surface and method for lining lumens of such devices to improve the frictional characteristics thereof. The catheter device includes a flexible elongated shaft which is formed of low durometer polymeric material, which can be readily folded or coiled for securing the shaft to or under the skin of the patient and a radiation lumen lined with high durometer polymeric material to improve the frictional characteristics. The elongated shaft has at least one inner lumen for receiving a radiation source which has a layer of high durometer polymeric material that provides lower surface friction to facilitate advancement of a radiation source therein.09-18-2008
20090054854MICRODIALYSIS CATHETER AND PROCESS FOR MANUFACTURE - A microdialysis catheter for partial implantation is used to supply a perfusion fluid and remove a dialysate, such as glucose, and comprises a carrier, at least one opening in the carrier, and a non-porous coating over the opening. The carrier contains at least one channel for supplying a perfusion fluid and for removing a dialysate and an area intended for implantation. The opening on the carrier has a connection with the channel for the passage of fluid. The non-porous coating is externally bonded to the carrier. The non-poroous coating is diffusion-permeable to an analyte and covers the area intended for implantation and the opening. A process for manufacturing the microdialysis catheter is also disclosed.02-26-2009
20090326484LONG NOSE MANIPULATABLE CATHETER - A long nose manipulatable catheter is described herein. The catheter generally comprises a flexible joint region defining a main lumen and an adjacent wire lumen. The wire lumen has an opening near or at a distal end of the flexible joint region and a push/pull wire can be pushed or pulled through the wire lumen. The catheter assembly may also comprise at least one radio-opaque marker band for securing the push/pull wire. The joint region has a predetermined length sized to affect a flexure of the joint and is generally located at the distal end of the catheter. The joint region itself may be varied to extend distally from where the braid terminates, or it may extend to encompass a portion of the braid. By varying a length of the joint region, the amount of curvature and flexure of the joint region can be controlled.12-31-2009
20080306454Apparatus And Method For Sterilization Of An Intravenous Catheter - An intravenous port and method of sterilizing an intravenous port via an ultraviolet (UV) light source are provided. The port comprises a catheter capable of being inserted into a blood vessel and an access head having a signal receptor, such as an antenna, and ultraviolet light source such as for example a light emitting diode (LED). A transmitter is further provided for delivering an electrical signal from a power source to the UV light source. The light source is suitable for directing UV light of a predetermined wavelength through the lumen of the catheter in a manner that incapacitates microorganisms residing in the catheter. The UV light is transmitted through the lumen of the catheter through a sterile solution that can be inserted into the port.12-11-2008
20090024097LUBRICIOUS COATINGS - The present disclosure provides substrates having a lubricious coating thereon. The substrate may be flexible and include, in embodiments, a medical device. The lubricious coating, in embodiments, is applied in a pattern so that the coating avoids delamination and/or fracturing which might otherwise occur as the substrate flexes and/or stretches.01-22-2009
20090198197THERAPEUTIC SLEEVE FOR IMPLANTABLE MEDICAL DEVICE - A therapeutic sleeve is disposable about a therapy delivery element. The sleeve has a first opening, a second opening, and a radially elastic body member disposed between the first and second opening. The body member forms a lumen extending from the first opening to the second opening and is configured to be disposed about the therapy delivery element. The sleeve further includes a therapeutic agent releasable from the body member when implanted in a patient.08-06-2009
20090099532Assembly for lubricating a portion of a medical device - A medical device assembly for imparting a lubricious and/or antimicrobial liquid onto a medical device is provided. The medical device is surrounded by a pouch and includes a burst package or frangible cells for storage of the liquid prior to delivery onto the surface of the medical device. This helps prevent contamination of the medical device upon removal of the medical device from its pouch, insertion of the device into a body cavity, and implantation of the device into the body cavity.04-16-2009
20090240214CATHETER WETTING SYSTEM AND METHOD - The present invention includes a system and method for wetting a catheter. The wetting system can include a catheter container, a fluid packet, and a catheter. The fluid packet and catheter container are adapted and configured to require opening the packet and moving the container to wet the catheter. The method includes opening the packet and moving the container to wet the catheter.09-24-2009
20090259202CATHETERS WITH LUBRICIOUS LININGS AND METHODS FOR MAKING AND USING THEM - Apparatus and methods are provided for substantially continuously forming thin-walled sleeves that may be incorporated into tubular devices sized for introduction into a patient. In one embodiment, a pair of sheets including coated surfaces oriented towards one another are directed through a cutting apparatus to cut the sheets into multiple pairs of strips. The pairs of strips are bonded together to create a plurality of sleeves having lumens defined by the coated surfaces. In another embodiment, a sheet having a coated surface is fed through a cutting tool to separate the sheet into a plurality of strips, and the strips are formed into sleeves, e.g., by feeding the strips through a die or mandrel using a substantially continuous process. Optionally, the sleeves may be subsequently cut into individual tubular devices and/or further processed, e.g., by providing one or more layers around the sleeves to create catheters, sheaths, or other apparatus.10-15-2009
20090076465COMPOSITE SEAL AND METHOD FOR MANUFACTURING - The present disclosure provides a composite surgical seal for use in a surgical access device which defines an access channel through it and includes a seal member configured and dimensioned to form a seal with a housing interior wall of a surgical access device. The seal member includes a layer defining an orifice therethrough and a fabric layer substantially encapsulating the resilient layer such that a surface of the resilient layer which defines the orifice is covered by the fabric layer. The access channel is configured and dimensioned such that insertion of a surgical instrument into the access channel causes the seal member to form a substantial sealing relation with the surgical instrument inserted therethrough. A method of forming a composite surgical seal in accordance with the present disclosure is also provided herewith.03-19-2009
20100211025APPARATUS AND METHODS FOR MAKING COATED LINERS AND TUBULAR DEVICES INCLUDING SUCH LINERS - A medical device includes a proximal end, a distal end sized for introduction into a body lumen, and a lumen extending between the proximal and distal ends. The tubular device includes an inner liner including a coating on an inner surface thereof, a reinforcing layer surrounding at least a portion of the liner; and an outer layer surrounding the reinforcing layer and inner liner. The liner and outer layer may include multiple sections having different properties than one another, adjacent sections attached together by seams, which may be offset from one another. Apparatus and methods for making tubular devices with coated liners are also provided.08-19-2010
20100087788Anti-infective alcohol catheter solution with chlorhexidine treated catheter - Implantable catheters treated with chlorhexidine and methods for disinfecting the catheters with alcohol are provided.04-08-2010
20130138052MULTI-FUNCTIONAL WIRE GUIDE ASSEMBLY AND METHOD OF USING SAME - A multi-functional wire guide assembly includes an elongate tubular housing having a length and defining a lumen extending from an open proximal end of the elongate tubular housing to an open distal end of the elongate tubular housing. A first mandril is positioned within the lumen, extends a majority of the length of the elongate tubular housing, and has a fixed position relative to the elongate tubular housing. A second mandril is positioned within the lumen, has a length greater than the length of the elongate tubular housing, and is axially movable relative to the elongate tubular housing. The multi-functional wire guide assembly has a first configuration in which a distal tip of the second mandril is proximally spaced from a distal segment of the elongate tubular housing and a second configuration in which the distal tip of the second mandril is axially aligned with the distal segment.05-30-2013
20110245782Method of Using Catheter with Rotating Portion - A catheter includes a proximal portion and a distal portion, the distal portion including an arcuate portion. The catheter further includes a rotating portion, the rotating portion connecting the proximal portion and distal portion, the rotating portion including a first piece and a second piece, wherein the first piece and second piece create a snap fit. Methods of using the catheter include threading the inserted catheter through the vasculature and allowing the distal portion to freely rotate about an axis defined by the rotating portion responsive to any tortuosity in the vasculature.10-06-2011
20100063459GELATIN-TRANSGLUTAMINASE HEMOSTATIC DRESSINGS AND SEALANTS - An adhesive material for medical use comprising gelatin and a non-toxic cross-linking material such as transglutaminase. An optional embodiment of the invention includes dressings in which a layer of a transglutaminase is sandwiched between a first and second layer of gelatin. The hemostatic products are useful for the treatment of wounded tissue.03-11-2010
20110152791MEDICAL INSTRUMENT - A medical instrument to be inserted into a living body before being used. The medical instrument is provided with a medical instrument main body including a long linear body having flexibility on which a coating layer covering at least the outer periphery on the distal side thereof is formed. The coating layer composes of a first layer which includes a material containing a low-friction resin material capable of lowering friction and a binder resin material serving as a binder; a second layer which is formed on the first layer and includes a material containing a low-friction resin material and a pigment and in which the content of a binder resin material is lower than the binder resin material content of the first layer or nil; and a third layer which is formed on the second layer and includes a material containing a low-friction resin material.06-23-2011
20110152790Systems, devices, and methods including catheters having self-cleaning surfaces - Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.06-23-2011
20110071478METHODS OF MANUFACTURING DRUG-LOADED SUBSTRATES - Described are methods for modifying a substrate by exposing the substrate to a densified fluid. The substrate may be a polymer or a metal alloy, and the densified fluid may be carbon dioxide. Uses of such substrate modification include impregnation of the substrate with one or more drugs, impregnation of microcellular particles, and formation of microcellular compositions.03-24-2011
20100036332ASPIRATION DRAINAGE SYSTEM COMPRISING A MATERIAL DEPOT WITH AN ANTI-BACTERIAL ACTION - The subject matter of the invention is an aspiration drainage system for aspirating secretions and other fluids out of the human or animal body using a suction tube and at least one material depot, arranged at the end of the suction tube to be inserted into the body, for dispensing an antibacterial active ingredient material. The surface of the material depot is larger than the envelope of the material depot. The increased surface of the material depot effects a higher level of the antibacterial active ingredient material and permits effective destruction in situ of both sensitive pathological germs and partially resistant germs.02-11-2010
20110009831ANTIMICROBIAL COATING FOR DERMALLY INVASIVE DEVICES - An antimicrobial coating applied to a transdermal surface of a catheter device. An antimicrobial coating applied to catheter device such that when the catheter device is fully inserted, the antimicrobial coating is interposed between the catheter device and the dermal layers of the patient.01-13-2011
20110054417BIOACTIVE AGENT RELEASE COATING AND CONTROLLED HUMIDITY METHOD - A coating composition in the form of a one or multi-part system, and method of applying such a composition under conditions of controlled humidity, for use in coating device surfaces to control and/or improve their ability to release bioactive agents in aqueous systems. The coating composition is particularly adapted for use with medical devices that undergo significant flexion and/or expansion in the course of their delivery and/or use, such as stents and catheters. The composition includes the bioactive agent in combination with a first polymer component such as polyalkyl(meth)acrylate, polyaryl(meth)acrylate, polyaralkyl(meth)acrylate, or polyaryloxyalkyl(meth)acrylate and a second polymer component such as poly(ethylene-co-vinyl acetate).03-03-2011
20110190712SACRIFICIAL CATHETER - A sacrificial catheter assembly and method of use for placing a functional catheter within the body of a patient, such as into the patient's vasculature, is disclosed. In one embodiment, the sacrificial catheter assembly comprises a sacrificial catheter including an elongate body that defines a longitudinally extending lumen. A stylet is removably received within the lumen of the sacrificial catheter such that the catheter and stylet can be advanced together to a target destination within the body of the patient. The sacrificial catheter is configured so as to then be proximally slid over the stylet to remove the sacrificial catheter from the body while the stylet remains in place at the target destination. A functional catheter can then be distally slid over the stylet to place the functional catheter at the target destination. The stylet can then be removed from the body of the patient.08-04-2011
20110152789Systems, devices, and methods including catheters having components that are actively controllable between two or more wettability states - Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.06-23-2011
20100030165CATHETER ASSEMBLY - A catheter assembly comprises an outer catheter including an outer catheter body and an outer catheter hub at a proximal portion of the outer catheter body; and an inner catheter including an inner catheter body insertable in the outer catheter body, a tip at the distal portion of the inner catheter body which is rich in flexibility, and an inner catheter hub at the proximal portion of the inner catheter body adapted to be coupled to the outer catheter hub. The inner catheter body includes a flexible section connected the tip, a physical property transition section on the proximal side of the flexible section, a first body section on the proximal side of the physical property transition section, a second body section on the proximal side of the first body section, greater than the first body section in flexural rigidity, and having a reinforcing material layer.02-04-2010
20100234815STABLE MELT PROCESSABLE CHLORHEXIDINE COMPOSITIONS - In a medical device having an antimicrobial agent, the medical device includes a base material and an amount of chlorhexidine or a pharmaceutically acceptable salt thereof disposed in the base material sufficient to reduce microbial growth. The base material is melt processed together with the chlorhexidine to generate the medical device which is substantially free of destabilized chlorhexidine.09-16-2010
20090024096IMMOBILIZATION OF DYES AND ANTIMICROBIAL AGENTS ON A MEDICAL DEVICE - A method for immobilizing dyes and antimicrobial agents on a porous surface is disclosed and described. The surface may be that of a medical device, such as a catheter, a connector, a drug vial spike, a bag spike, a prosthetic device, an endoscope, and surfaces of an infusion pump. The surfaces may also be one or more of those associated with a dialysis treatment, such as peritoneal dialysis or hemodialysis, where it is important that working surface for the dialysis fluid be sterile. These surfaces include connectors for peritoneal dialysis sets or for hemodialysis sets, bag spikes, dialysis catheters, and so forth. A method for determining whether a surface has been sterilized, and a dye useful in so indicating, is also disclosed.01-22-2009
20090287166INTEGRATED DEVICE FOR ISCHEMIC TREATMENT - A system and method in accordance with the present invention provides a infusion catheter that is flexible, has such a smooth traction and a low profile to minimize break up of the obstruction when crossing it, can access distal vasculature quickly, is easy to use and readily to be implemented in the conventional PCI. Another object is to provide a method that can be performed within a short period of time and employs the catheter described herein to infuse a therapeutic agent distally to the obstruction before it is removed as a means of reducing reperfusion injury, protecting distal vasculature and microcirculation, preserving myocytes, reducing infarct size and ischemic damages in the heart, brain, lung, liver, kidney and limb. Another object is to provide complementary feature options to the infusion catheter and the aspiration catheter to improve the speed and quality of the vessel clearance.11-19-2009
20100198168HYDROPHILIC COATING - The invention relates to a coating formulation for preparing a hydrophilic coating, wherein the hydrophilic coating formulation comprises a supporting monomer and/or polymer comprising at least 2 reactive moieties capable of undergoing polymerization reactions, a polyelectrolyte, a Norrish Type I photoinitiator, and a Norrish Type II photoinitiator.08-05-2010
20120046622METHOD AND APPARATUS FOR MAKING A POROUS BIODEGRADEABLE MEDICAL IMPLANT DEVICE - A method of producing a porous biodegradable medical implant device, the method comprising providing a mixed blend comprising a mixture of at least two biocompatible materials having different degradation or solubility characteristics; molding the mixed blend to produce a molded part; and processing the molded part to remove one of the at least two biocompatible materials by a predetermined amount from the molded part to produce the porous biodegradable medical implant device.02-23-2012
20120022470MEDICAL ELONGATE MEMBER HOUSING TOOL AND MEDICAL ELONGATE MEMBER HOUSING TOOL ASSEMBLY - An elongate member housing tool assembly includes a distal end side tubular member disposed on the distal end side and a proximal end side tubular member disposed on the proximal end side, which accommodate an elongate member, and a liquid inlet port to which a liquid supplying tool for supplying liquid into the distal end side tubular member is removably connected and which is provided on the distal end side tubular member. The distal end side tubular member and the proximal end side tubular member are wound spirally, and the proximal end of the distal end side tubular member and the distal end of the proximal end side tubular member are disposed in a spaced relationship from each other. A distal portion of the guide wire is accommodated in the distal end side tubular member, except possibly the most distal portion of the elongate member.01-26-2012
20120022469NEEDLELESS VALVE INFECTION PREVENTION AND PRE-OPENING DEVICE - A disinfecting and pre-opening device is disclosed for use with a female needleless connector. The disinfecting and pre-opening device includes a housing comprising a chamber having a distal opening and configured to fit over the female needleless connector, and an elongated finger attached to the housing and disposed within the chamber such that the elongated finger opens the fluid path through the female needleless connector when the distal opening of the disinfecting and pre-opening device is placed proximally adjacent to the septum and the disinfecting and pre-opening device is advanced in the distal direction.01-26-2012
20100094230POLYMER MOLDING COMPOUNDS CONTAINING PARTIALLY NEUTRALIZED AGENTS - The invention relates to polymer molding compositions rendered antibacterial, antiprotozoic, or antimycotic by using partially neutralized active ingredients, to processes for their production, and to their use in moldings, in particular in medical items.04-15-2010
20090131884MEDICAL DEVICE FOR INSERTION INTO THE HUMAN BODY, AND METHOD OF MANUFACTURE - A medical device for insertion into the human body has improved sliding characteristics. The medical device for insertion into the human body includes a substrate having given shape, and an agent for improving the sliding characteristics having a hydrophilic block and a hydrophobic block, and coating the hydrophobic surface.05-21-2009
20090131883ANTIMICROBIAL GAS-RELEASING EAR DRAINAGE TUBES - A nitric oxide gas-releasing conduit configured for surgical implantation through a patient's tympanic membrane. The nitric oxide gas-releasing conduit comprises a gas-permeable cured resin material configured for releasably sequestering therein gas. The gas-permeable cured resin material is charged with nitric oxide gas. The nitric oxide gas-releasing conduit may be optionally coated with an antimicrobial gas-releasing composition. The gas-releasing coating composition may be configured to release nitric oxid.05-21-2009
20100174245System for pretreating the lumen of a catheter - A method of and system for pretreating the lumen of a catheter or small diameter tubing. A vacuum chamber includes a microwave port and a microwave supply subsystem including a microwave generator, and a circular polarizer produces circularly polarized microwaves propagated into the vacuum chamber via the port at a frequency which produces electron cyclotron resonance. A magnetic coil about the vacuum chamber generates a magnetic field in the vacuum chamber with magnetic field lines co-linear with the propagation direction of the microwaves. A catheter manifold positions at least one catheter in the vacuum chamber and supplies a gas within the catheter lumen to generate a plasma in the lumen for pretreating the same.07-08-2010
20100174246Medical Guide Wire and Method of Forming Thereof - A guide wire for guiding a medical device within a body lumen is described. The guide wire includes a proximal section, a distal section, and a mid section. The proximal section includes a proximal wire core tapered with contraction towards a proximal end of the proximal wire core. The distal section includes a distal wire core tapered with contraction towards a distal end of the distal wire core. The mid section includes a joint for joining the proximal wire core and the distal wire core. The guide wire also includes a safety wire extending along the mid section, and along at least parts of the proximal and distal sections. Moreover, the guide wire includes an outer tubing enveloping the overlapping joint and at least parts of the proximal and distal sections.07-08-2010
20130172827DISPOSABLE INTRAMEDULLARY DEVICE FOR TEMPORARY USE FOR TREATMENT OF LIMB INFECTIONS - A disposable intramedullary device for temporary use for treatment of limb infections comprising a solid core of variable cross-section, including a distal portion, a middle portion and a proximal portion, said proximal portion and distal portion including anchoring regions consisting of through-holes being passed through by bone anchoring means. Outside said anchoring regions, said solid core is coated with a polymer layer which also includes antibiotic, the outer diameter of the solid core and polymer layer assembly being equivalent to that of an intramedullary channel, and the outer diameter of said solid core in said anchoring regions being equivalent to that of a said intramedullary channel.07-04-2013
20100049147THROMBUS-ASPIRATION CATHETER - It is intended to provide a thrombus-aspiration catheter capable of exerting flexibility and aspiration force even in the case where the tube in the front end side is a triple lumen tube or a contrast marker is provided at the front end. A thrombus-aspiration catheter comprising a basal end side tube of the double lumen type which has an aspiration lumen and a core wire lumen, and a front end side tube of the triple lumen type which has a guide wire lumen in addition to the aspiration lumen and the core wire lumen, wherein the front end of the above-described front end side tube is obliquely cut and a terminal aspiration tube of a flexible double lumen, which has a front end opening inclined in almost the same direction as the cut face, is connected to the cut face.02-25-2010
20100274201Antimicrobial agent delivery system - An antimicrobial agent delivery system and method are provided for an antimicrobial agent-bearing intervention device. A delivery tube contains the intervention device, where the delivery tube facilitates handling of the intervention device. In one example, the intervention device is a rod, and a hub is coupled to the rod. Longitudinal movement of the hub ejects the rod from the delivery tube.10-28-2010
20100010456System and Method for the Prevention of Bacterial and Fungal Infections Including Urinary Tract Infection (UTI) Using N-Halogenated Amino Acids - Disclosed is a system that prevents the development of infection and biofilm establishment in medical devices in general, and in particular Urinary Tract Infections (UTI), including Catheter-Associated Urinary Tract Infections (CAUTI). The system comprises a medical device (such as a catheter) and an antimicrobial composition containing an antimicrobial compound. A medical device delivers the composition both to the inside and/or outside portions of the device, as well as to the inside of the bladder itself and to the urethra. Reduction or elimination of the infection may be accomplished by irrigating the medical device, bathing the bladder, or irrigating the bladder with the composition.01-14-2010
20120253296MEDICAL APPARATUS WITH LUBRICITY AND MANUFACTURING METHOD OF SAME - The present disclosure provides a medical instrument with a coating that provides excellent lubricity when wet. The medical instrument possesses a coating including a wet lubricating film with high peel durability and anti-eluting properties. In embodiments, an intermediate film made of bisphenol A type epoxy resin is coated on a base material of a medical instrument made of metal, and a wet lubricant coating produced by alkaline processing of a polymer alloy containing a methyl vinyl ether maleic anhydride copolymer and a polyether block amide is then applied thereto. Methods for making these medical instruments are also provided.10-04-2012
20120271248MARKED PRECOATED MEDICAL DEVICE AND METHOD OF MANUFACTURING SAME - A method of manufacturing a coated medical device, such as a medical guide wire, including at least applying a first colored coating to at least a first portion of an outer surface of a medical guide wire, securing a first end of the medical guide wire, and for each a designated quantity of turns, turn a second end of the medical guide wire upon a longitudinal axis of the medical guide wire. The method of manufacturing also includes securing the second end of the medical guide wire, blocking at least a first portion of the coated surface of the medical guide wire, applying a second contrasting colored coating to at least a second, unblocked portion of the outer surface of the medical guide wire and releasing the first end and the second end of the medical guide wire to display at least one spiral marking formed along a length of the medical guide wire.10-25-2012
20080300554LUBRICANT FOR MEDICAL DEVICES - A formulation and method for providing medical devices with a lubricious and non-toxic coating Medical devices having a lubricious, non-toxic coating.12-04-2008
20120323189CATHETER SHAFT WITH IMPROVED MANIFOLD BOND - A catheter shaft with an improved manifold bond and methods for making and using the same. The catheter shaft may include a sleeve disposed, for example, near its proximal end. The sleeve may include a first layer that is attached to the catheter shaft and a second layer to which a hub or manifold may be attached.12-20-2012
20110046575PERCUTANEOUSLY ABSORBABLE PREPARATION, PERCUTANEOUSLY ABSORBABLE PREPARATION HOLDING SHEET, AND PERCUTANEOUSLY ABSORBABLE PREPARATION HOLDING EQUIPMENT - Self-dissolving needle-like or filamentous shape percutaneously absorbable preparations, by which inherently poorly absorbable drugs into the body through the skin is efficiently administered. The preparations are made of at least one material selected from the group consisting of proteins, polysaccharides, polyvinyl alcohols, carboxyvinyl polymers and sodium polyacrylic acids. An active substance contained therein is released in a sustained-release fashion (1) by forming a water-insoluble layer on its surface, (2) by holding the active substance in porous materials, or (3) by imparting a long-acting characteristic to the active substance. The present invention also provides a sheet-like carrier for holding the preparations on at least one of the sides thereof, and a piece of equipment for holding the preparations so as to facilitate the administration of them.02-24-2011
20110238019RESORBABLE INTRA-URETHRAL PROSTHESIS - The device made in a resorbable material intended to be placed in urethra for Treatment of stricture has the shape of a tube (09-29-2011
20120277690DEGRADABLE REMOVABLE IMPLANT FOR THE SUSTAINED RELEASE OF AN ACTIVE COMPOUND - A degradable, removable, pharmaceutical implant for the sustained release of one or more drugs in a subject, wherein the pharmaceutical implant is composed of a tube comprising an outer wall made of a degradable polymer completely surrounding a cavity, wherein the outer wall has a plurality of openings and wherein the cavity contains one or more sets of micro-particles, which micro-particles contain an active agent or a combination of two or more active agents, and wherein the size of the microparticles is selected such that the majority of the microparticles cannot pass through the openings.11-01-2012
20120150131Polymer for Controlling Delivery of Bioactive Agents and Method of Use - A medical device includes a base material and chlorhexidine or a pharmaceutically acceptable salt thereof disposed in the base material sufficient to reduce microbial growth. The base material includes a polymer having a silicone monomer and a urethane monomer.06-14-2012
20110160681Systems, devices, and methods including catheters having light removable coatings based on a sensed condition - Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.06-30-2011
20110160680WIRE GUIDE WITH CANNULA - The present invention generally relates to a medical surgical device and specifically a wire guide for percutaneous placement within a body lumen. The wire guide includes an elongated mandrel having sufficient flexibility and kink resistance and a cannula having a stiffness greater than the mandrel stiffness for sufficient pushability. The mandrel extends through the cannula and has a portion extending distal thereto to form a distal tip of the wire guide. The wire guide can further include a slotted cannula to improve the flexibility of the wire guide at the proximal portion of the wire guide. The slots can be arranged in various patterns for increased flexibility along the longitudinal length of the cannula, as well as increased circumferential flexibility along the wire guide. The mandrel may also have a proximally tapered portion to improve the flexibility of the wire guide at the proximal portion of the wire guide.06-30-2011
20080249482Self catheterization kit - A kit for self-catheterization is disclosed. The kit includes a sealed enclosure including a fastener for fastening the enclosure to an individual and self-catheterization supplies located within the enclosure, wherein the supplies include a catheter, lubrication, gloves and an antimicrobial agent. The kit further includes a separate sealable compartment within the enclosure for receiving drained urine during self-catheterization. In one alternative, the fastener comprises a cord for placement around the individual's neck, wherein the enclosure is coupled to both ends of the cord. In another alternative, the fastener comprises a hook and loop element for attaching the enclosure to the individual's clothing.10-09-2008
20100234816COATED WIRE GUIDE AND METHOD OF MAKING SAME - In at least one embodiment, a method for making a wire guide is provided. The method comprises applying a polymer coating to a proximal section of a FP coated core wire having a FP coating disposed thereon such that the polymer coating overlays at least a portion of the FP coating. The polymer coating is applied to a distal section of the FP coated core wire having an exposed metal portion such that the polymer coating overlays at least a portion of the exposed metal portion. The polymer coating is removed from the proximal portion of the FP coated core wire to form the wire guide having a proximal portion with the FP coating and a distal portion with the polymer coating.09-16-2010
20100234814Method and Subcutaneous Apparatus for Facilitating the Replacement of an Implanted Catheter - A medical apparatus and method of use for implanting a catheter in a patient's body which catheter can be easily positioned, repositioned, and replaced. The apparatus includes an elongate sleeve intended to be subcutaneously implanted. The sleeve comprises a wall surrounding an interior elongate passageway which extends from a sleeve proximal end to a sleeve distal end. The sleeve outer peripheral surface carries a layer of porous material intended to be placed just under the patient's outer skin layer in contact with the dermis to promote tissue ingrowth for anchoring the sleeve and forming an infection resistant barrier. The sleeve passageway includes a sealing nib dimensioned to engage the outer surface of the catheter while permitting the catheter to slide relative to the sleeve. The sealing nib prevents deleterious material from migrating into the patient's body along the catheter outer surface.09-16-2010
20090171303Fixed- or Variable-Length, Wire-Reinforced Catheter and Method of Adaptation - This disclosure relates to a fixed- or variable-length, wire-reinforced catheter for use in a human body or connected to a subcutaneous port implanted in a human body for use under a cyclical internal load and method of adaptation thereof, and more particularly, to a wire-reinforced catheter of increased internal diameter or reduced external diameter of fixed or variable lengths for the optimized transportation of blood under cyclical internal load and without damage.07-02-2009
20080215016Medical Tubes - Medical tubes are well balanced in transparency, flexibility, heat resistance, scratch resistance and rubber elasticity.09-04-2008
20130150809METHODS AND SYSTEMS FOR COATING A MEDICAL DEVICE - An antimicrobial coating system and method are described. In some embodiments, a system may include a composition. The composition may include one or more bridged polycyclic compounds. At least one of the bridged polycyclic compounds may include at least two cyclic groups, and at least two of the cyclic groups may include quaternary ammonium moieties. In some embodiments, a method may include applying an antimicrobial coating to an oral surface, a surface of a construction substrate, a surface of a marine substrate, a surface of a medical device, or a surface of a personal care device. The protective coating may be antimicrobial. A protective coating may include antimicrobial bridged polycyclic compounds. Bridged polycyclic compounds may include quaternary ammonium compounds. Bridged polycyclic compounds based coating systems may impart self-cleaning properties to a surface (e.g., a tooth surface).06-13-2013
20100318040Catheter Locking Solution Having Antimicrobial and Anticoagulation Properties - The present invention includes a catheter locking solution having both antimicrobial and anticoagulant properties including a local anesthetic and a viscosifying agent. The local anesthetic of the present invention may be an amino amide; an amino ester; an aminoacylanilide; an aminoalkyl benzoate; an amino carbonate; an N-phenylamidine compound; an N-aminoalkyl amid; an aminoketone, or combinations and mixtures thereof. In a particular embodiment of the present invention, the local anesthetic is tetracaine or dibucaine.12-16-2010
20120283667Medical Lumen Access Device Assembly Including Medical Lumen Access Device Holder And Method of Use - A medical lumen access device assembly includes a medical lumen access device holder including an elongate tube defining a lumen extending from a proximal opening of the elongate tube to a distal opening of the elongate tube. A check valve is positioned over an opening of the elongate tube and includes a valve member having a biased closed position wherein an internal volume defined by the lumen is fluidly blocked from an exterior of the elongate tube at the opening and an open position defining a fluid path from the exterior to the internal volume through the opening. The medical lumen access device assembly also includes a medical lumen access device disposed at least partially within the lumen and having a proximal segment extending beyond the distal opening. At least a portion of the medical lumen access device includes a hydrophilic coating.11-08-2012
20120283666DRUG ELUTING COCHLEAR IMPLANTS - Drug delivery systems and biocompatible coatings for use with implantable stimulation devices such as cochlear implants have been developed. These drug delivery systems and coatings comprise polyhydroxyalkanoate (PHA) polymers and copolymers. The drug delivery systems may be used to deliver pharmacologically active substances, for example, directly from a cochlear implant to the inner ear. The coatings can impart lubricity to cochlear devices for ease of insertion of the electrodes. In the preferred embodiment, the drug delivery system comprises a polyhydroxyalkanoate polymer, and in the most preferred embodiment, the PHA polymer comprises poly(4-hydroxybutyrate) (P(4HB)) or copolymer thereof. A particularly preferred embodiment is where the silicone sheath of the cochlear implant electrodes has been surface modified, and coated with P(4HB), and the P(4HB) either contains a pharmacologically active substance or has been coated with such a substance.11-08-2012
20130184659LUBRICIOUS EXTRUDED MEDICAL TUBING - A medical tube having improved lubricity is disclosed. The medical tube is produced by extruding a polymer material blended with a lubricity enhancing additive through a resilient die. The polymer material can be medical-grade high-density polyethylene, and the lubricity enhancing additive can be a silicone-based or alloy-based material. The medical tube can include one or more internal elongated protuberances so as to reduce the internal surface area of the medical tube available to generate friction on a guide wire inserted or withdrawn through the medical tube.07-18-2013
20130123715Indwelling catheter probe incorporating proanthocyanidines - An indwelling catheter probe, wherein it incorporates, at its external and/or internal surface, an extract of 05-16-2013
20130123714VESSEL PROTECTION MEMBRANE - A medical device assembly may include an elongated guidewire, an elongated flexible tubular membrane disposed about the guidewire, and a percutaneous medical device, wherein the membrane is configured to permit the percutaneous medical device to pass through the lumen. A method of advancing a medical device through a vessel may include advancing an elongated flexible tubular membrane through the vessel to a treatment site, inserting the medical device into the membrane, and advancing the medical device through the membrane while maintaining the membrane in an axially stationary position relative to the vessel.05-16-2013
20130190701MEDICAL TUBE UNCLOGGING SYSTEM AND RELATED METHOD - A medical tube unclogging system includes a power supply, a reservoir of fluid, a tube for insertion into a lumen of a medical tube having a clog therein, a pump powered by the power supply and connected to the tube for generating a flow of fluid from the reservoir of fluid through the tube, a fitting through which the tube passes having a first opening coupled to the medical tube, a second opening for receiving the tube, and a third opening through which fluid pumped through the tube and into the medical tube, and fragments of the clog can be exhausted. The system may also include a sensor for monitoring a pressure of the fluid flowing through the tube and producing a signal indicative of the pressure, and a controller or processor for receiving the signal from the sensor and adjusting the pump.07-25-2013
20130197455DRUG RELEASING MEDICAL CATHETERS, TUBES, AND DEVICES - The present disclosure relates to medical catheters, tubes, and other medical devices, systems, and methods. The catheter, tube, or other medical device is capable of releasing drugs for extended periods of time. Drugs can be loaded into the wall thereof with a loading solution. The drug in the wall of the device and in the loading solution can be in dynamic equilibrium, yielding stable and easy-to-manufacture products.08-01-2013
20120083750Antimicrobial Luer Adapter - A luer adapter includes a body including an inner surface defining a lumen and first and second ends. Each end is adapted to connect to a medical device. An antimicrobial material is positioned at least on a portion of the inner surface. A barrier is positioned between the lumen and the antimicrobial material and permits the passage of the antimicrobial material therethrough upon exposure to moisture. The barrier may include hydrophilic material.04-05-2012

Patent applications in class With body soluble, antibactericidal or lubricating materials on conduit