Class / Patent application number | Description | Number of patent applications / Date published |
604103010 | Delivering fluid or material through wall of inflated means | 38 |
20080208118 | MULTI-FUNCTION CATHETER AND USE THEREOF - A catheter for delivering an agent to an area of treatment is presented. The catheter includes a catheter body, a balloon assembly coupled to the catheter body, a first lumen, and a second lumen. The balloon assembly has spaced-apart balloons that define an area between the balloons. The first lumen extends along the catheter body to pass an inflation material to the balloons to control an inflation level of the balloons. The second lumen extends along the catheter body and having an outlet in the area between the balloons. There may be a third lumen for bypassing a biological fluid such as blood while the catheter is being used. The method of using this catheter is also presented. The method entails simultaneously inflating the balloons to isolate a treatment area and adding an agent to the treatment area through one of the lumens. | 08-28-2008 |
20080243068 | METHODS AND APPARATUS FOR TREATMENT OF VENOUS INSUFFICIENCY - Methods and apparatus for the treatment of venous insufficiency, such as varicose veins, are described herein utilizing endovenous treatments. Such treatments may include systems to create an initial endovascular injury to the vessel wall utilizing any number of mechanisms, such as chemical, mechanical, electrical, etc. modalities. An implantable device, optionally having a sclerosing agent infused therein, may additionally be implanted along the injured tissue to promote, maintain, and otherwise enhance the tissue inflammation and scarring, thereby remodeling the diseased vessel wall. | 10-02-2008 |
20080281263 | DISTAL PROTECTION DEVICE WITH LOCAL DRUG DELIVERY TO MAINTAIN PATENCY - The present invention provides for a drug delivery mechanism for use with a protection device. The protection device has an expandable filter. The drug delivery mechanism automatically delivers a drug to the filter without requiring the intervention of the operator of the protection device. The drug delivered to the filter facilitates continued filter patency during the medical procedure. | 11-13-2008 |
20080294102 | Balloon Cannulae - A vascular catheter with a circular external diameter, a circular lumen contained within, and an inflatable balloon that overlies a trough in the catheter body such that when the balloon is deflated, the balloon does not protrude beyond the outer circumference of the catheter shaft. The wall of the catheter shaft is thicker along one side than along the remainder of the circumference of the catheter shaft to permit an inflation lumen to be disposed within the thick wall section without increasing the outer diameter of the remaining portion of the circumference. The inflatable balloon is further disposed to maintain the circular lumen of the catheter in the center of flow of the blood vessel in which it is used, maintaining optimal flow. The combination of the circular lumen, circular outer diameter, and recessed balloon trough produces improved hemodynamic flow characteristics within the cannula over existing balloon cannula designs, minimizing flow-related injuries that might cause embolization or vascular dissection. | 11-27-2008 |
20090012468 | DISTAL PROTECTION DEVICE WITH LOCAL DRUG INFUSION BY PHYSICIAN TO MAINTAIN PATENCY - The present invention provides for a local drug delivery mechanism for use with a protection device. An infusing device is used to charge the drug into the catheter lumen toward a distal portion of the lumen having a plurality of drug delivery exit ports. The drug exits the ports into the patient's vascular system and is able to flow toward a filter maintaining the patency of the filter. | 01-08-2009 |
20090018501 | Drug Coated Balloon Catheter - The present invention relates to balloon catheters for treating a luminal system of a patient. Specifically, the invention relates to catheters having a flexible membrane positioned at a distal portion of the catheter, the flexible membrane retained in a substantially unexposed conformation prior to deployment. Preferably the flexible membrane is capable of delivering a therapeutic agent to a localized environment when deployed to an exposed conformation. | 01-15-2009 |
20090076448 | Methods and devices for eluting agents to a vessel - Systems, devices and methods for eluting an agent at a treatment site are disclosed. The devices include an expandable frame and at least one membrane. The membrane may carry an agent to elute at the treatment site. The membrane may allow blood flow at the treatment site during agent delivery. | 03-19-2009 |
20090093758 | Fibroid treatment apparatus and method - Apparatus is provided, including a tube that is passed into a patient's vagina and to penetrate vaginal tissue until a distal tip of the tube is outside of a uterine artery of the patient, but in a vicinity of a portion of the uterine artery that supplies a uterine fibroid. A balloon, disposed at the distal tip, is inflated to cause local squeezing of the portion of the uterine artery to an extent sufficient to occlude the uterine artery. Other embodiments are also described. | 04-09-2009 |
20090171281 | SYSTEMS AND METHODS FOR LOCATING AND CLOSING A TISSUE PUNCTURE - A vascular closure device includes a main body and an expandable portion that can be selectively expanded and contracted. The vascular closure device may be used to close the hole in a wall of a vessel after a medical procedure. For example, the vascular closure device may be used to close the hole in an artery after a medical procedure that required access to the artery. In one embodiment, the expandable portion may be oriented at an oblique angle relative to the main body. This may be desirable in situations where the vessel puncture is oriented at an angle relative to the vessel. Orienting the expandable portion at an oblique angle relative to the main body may help the expandable portion to cover the hole in the wall of the vessel. | 07-02-2009 |
20090171282 | VASCUAR CLOSURE DEVICE HAVING A FLOWABLE SEALING MATERIAL - Various embodiments of a device are shown and disclosed for closing a vascular access puncture site following percutaneous diagnostic or therapeutic interventional procedures. The vascular closure device is configured to safely and accurately deploy a sealing material that undergoes a phase change when deployed inside the tissue tract. The sealing material may be a solid at room temperature and a liquid or gel at body temperature. Also, the sealing material may change from a liquid or gel to a cubic phase when it comes into contact with bodily fluids. | 07-02-2009 |
20090192454 | CATHETER FOR CELL DELIVERY - A cell delivery system and method for delivering cells locally to a tissue, body cavity, or joint is described. The cell delivery system comprises a catheter configured to deliver stem cells in a pressure controlled manner. The catheter may comprise an inner bladder and an outer perforated bladder. The inner bladder may be expanded through the use of a pressure conduit in order to deploy a stent. Cells, such as endothelial cells derived from adipose tissue, may be introduced between the inner and outer bladder. The inner bladder may be further expanded in order to exert pressure on the outer perforated bladder to advance the stems cells though the apertures of the outer bladder. The inner bladder may remain pressurized to hold the outer bladder against the vessel wall, thereby directing the stem cells to specific target sites. The system may be used to deliver stem cells with or without other therapeutic agents. The system may be used with or without a stent. The system may further comprise a pressure gauge that permits measurement and regulation of pressure within the catheter. | 07-30-2009 |
20090264821 | Endolumenal Sealant Delivery Apparatus and Methods - Endolumenally sealing a zone around the puncture and dilation area of a stent-graft fenestration or sealing the juncture between two lumens with an expandable sealant delivery device. In exemplary embodiments, an expandable sealant delivery device includes a catheter mounted balloon, which has a microporous membrane or a plurality of pores suitable for delivering a surgical sealant. | 10-22-2009 |
20090318863 | Functional Balloon With Built in Lubricity or Drug Delivery System - The present invention is directed to expandable medical balloons that have strips of lubricous material along their lengths The expandable medical balloons are formed from extruded preform segments. The preform segments are coextrusions of a first material, which forms the tubular primary material of the preform segments, and a second material, which forms the strips of lubricous material. | 12-24-2009 |
20100056999 | A METHOD AND A CATHETER DEVICE COMPRISING AN INFLATABLE BALLOON FOR THE DYNAMIC REGULATION OF THE VENOUS RETURN TO THE HEART - A hydro-mechanical devices which regulate venous return flow in the human circulatory system includes a combined catheter/cyclic occlusion inflatable balloon to regulate the venous return, which can be adapted to its location space in the inferior vena cava, near the right entrance of atrium, and includes means for retention inside the vessel as well as an ability to modify volume according to patient's needs. | 03-04-2010 |
20100087782 | CATHETER BALLOON HAVING STRETCHABLE INTEGRATED CIRCUITRY AND SENSOR ARRAY - A system, device and method are presented for utilizing stretchable active integrated circuits with inflatable bodies. The invention allows for such operative features to come into direct contact with body structures, such as the inner wall of a lumen. Such direct contact increases accuracy of measurement and delivery of therapy. | 04-08-2010 |
20100211009 | PERFUSION CATHETER HAVING ARRAY OF FUNNEL SHAPED MEMBRANES - An agent delivery catheter configured to deliver an agent to an inner surface of a patient's body lumen wall by forming an array of cells defining agent containment chambers at multiple locations along the catheter's shaft, while minimizing ischemic conditions during the procedure. | 08-19-2010 |
20100249702 | POROUS CATHETER BALLOON AND METHOD OF MAKING SAME - A porous balloon or other catheter structure is formed by creating specific size pores for delivering an agent to a body lumen. The pores can be created by passing matter or energy through the surface of the catheter structure, as by a laser or a projectile. In the case of a laser, the catheter structure can be reversed so that the inner surface becomes the outer surface to convert diverging pores into converging pores. In the case of projectiles, a pore size can be achieved by selecting an appropriate size and shaped projectile to obtain the desired characteristic. Alternatively, a material to make the catheter structure can include impurities that can be removed once the catheter structure is set, leaving pores where the material formed around the impurities. | 09-30-2010 |
20100280452 | MEDICAL DEVICES HAVING MULTIPLE LAYERS - Described herein are medical devices which are configured for implantation or insertion into a subject, preferably a mammalian subject. The medical devices contain one or more multilayer regions, which contain: (a) one or more (typically a plurality of) charged nanoparticle layers and (b) one or more (typically a plurality of) charged polyelectroyte layers. Such multilayers have a number of desirable attributes, including high strength, non-compliance, and flexibility. Also described herein are methods of making such devices. | 11-04-2010 |
20100286608 | DRUG-COATED BALLOON CATHETER AND METHOD FOR THE PRODUCTION THEREOF - The invention relates to a drug-coated balloon catheter and to a method for producing the same. The balloon of the catheter includes (i) a main membrane, and (ii) an asymmetrical polymer membrane which is applied to an outside of the main membrane and into which at least one pharmaceutical active ingredient is introduced. | 11-11-2010 |
20110166516 | BALLOON CATHETERS HAVING A PLURALITY OF NEEDLES FOR THE INJECTION OF ONE OR MORE THERAPEUTIC AGENTS - There are disclosed apparatus and methods for treating tissue by delivering at least one therapeutic agent into the tissue. In one embodiment, the apparatus comprises a catheter ( | 07-07-2011 |
20110190698 | Method and Apparatus for Delivering an Agent to a Kidney - Devices for delivering drugs or other treatment agents locally to the vasculature of a mammal are disclosed. These devices have several related structures and are designed to deliver the drugs to facilitate rapid mixing with the blood flowing past the devices. | 08-04-2011 |
20110245766 | Method and Apparatus for Improving Delivery of an Agent to a Kidney - Methods for more uniformly delivering drugs or other treatment agents locally to the vasculature of a mammal are disclosed. These methods use one or more strategies to facilitate rapid mixing with the blood flowing past a device or otherwise improve the uniformity of drug delivery. Some of these strategies employ medical devices with diffusion members. | 10-06-2011 |
20110264039 | Expandable perfusion balloon - A balloon catheter for dilation of stenotic tissue within a tubular member of the body such as a blood vessel provides fluid flow such as blood flow through the balloon while it is being inflated and after it has been inflated. For valvuloplasty applications or for predilitation prior to a TAVI procedure the balloon is placed across the stenotic aortic valve leaflets and inflated to push the leaflets aside to create a greater blood flow area or allow improved subsequent passage of the large TAVI catheter across the stenotic aortic valve leaflets. As the balloon is inflated in diameter, it is required to reduce in length; this length reduction causes a braided inner tubing to also reduce in length. The braided inner tube is thereby required it to increase in diameter during the balloon inflation and create a suitably large blood flow path through the inner tubing. The continuous perfusion through the inner tubing of the balloon allows greater balloon inflation times, improved valvular dilation, and obviates the need for rapid pacing during the valvuloplasty procedure. | 10-27-2011 |
20110306928 | MEDICATION INFUSION KIT - Embodiments of the present invention include a self-powered infuser with a medicament containing vessel coupled to the infuser capable of exerting sufficient pressure to cause a medicament to flow from the containing vessel, through intravenous tubing, and into a patient's circulatory system. The infuser and vessel may be contained within a sealable kit which may have a separate container for perishable medications such that the medications may be inspected and changed without exposing the remainder of the kit's contents. The infuser may be recyclable or disposable. | 12-15-2011 |
20120109057 | APPARATUS AND METHODS FOR TREATING OBSTRUCTIONS WITHIN BODY LUMENS - An apparatus is provided that is operable in different modes to perform various functions for treating a body lumen. The apparatus includes a shaft including a proximal end, a distal end, a lumen extending therebetween, and a balloon on the distal end having an interior communicating with the lumen. The apparatus includes a valve on the distal end that selectively opens or closes an outlet communicating with the lumen. With the valve open, fluid introduced into the lumen exits the outlet into a body lumen. With the valve closed, fluid introduced into the lumen expands the balloon. The apparatus also includes an actuator for axially compressing the balloon, and a helical member extends between ends of the balloon interior that expands the balloon from a contracted condition to an expanded helical shape when the actuator is activated. | 05-03-2012 |
20120116305 | DRUG DELIVERY MEDICAL DEVICES - Medical devices for delivering a bioactive agent and methods of use thereof are provided. The medical devices include micro-needles integrated within a balloon of a catheter. The balloon can include dimples, cavities or a variable thickness membrane in which the micro-needles are integrated. | 05-10-2012 |
20120123331 | BALLOON CATHETER SYSTEM - A balloon catheter system enables only a target site to be efficiently ablated, ensuring a balloon to be able to be brought into close contact with the target site in conformity to a shape of the target site. The balloon includes a contact portion that contacts the target site and a noncontact portion that does not contact the target site. A membrane thickness of the contact portion is thinner than that of the noncontact portion The target site that is in contact with the thin contact portion is selectively ablated, while the thick noncontact portion is less likely to exhibit a temperature increase. Hence, only the target portion is efficiently ablated. | 05-17-2012 |
20120220933 | Therapeutic Delivery Devices, Systems, and Methods for Multiple Sclerosis, Deep Vein Thrombosis, and Pulmonary Embolism - Methods and devices are disclosed that, in various embodiments and permutations and combinations of inventions, diagnose and treat Multiple Sclerosis, Deep Vein Thrombosis, and/or Pulmonary Embolism or symptoms associated with these maladies. In one series of embodiments, the invention consists of methods and devices for identifying patients whose Multiple Sclerosis, Deep Vein Thrombosis, and/or Pulmonary Embolism or associated symptoms are caused or exacerbated, at least in part, by blockages of one or more of the patient's veins. In some instances, stenoses or other flow limiting structures or lesions in the patient's affected veins are identified. Further, in some instances the nature of such lesions and whether there is a significant disruption of blood pressure, or both, is ascertained. In some embodiments, methods and devices for applying one or more therapies to the blockages in the patient's veins are provided. | 08-30-2012 |
20120226230 | Nested Balloon Catheter for Localized Drug Delivery - A balloon catheter for delivering a therapeutic and/or diagnostic agent to tissue is described including an outer balloon having a wall with an opening therethrough and an inner surface, an inner balloon disposed in the outer balloon, enclosing an inflation chamber and having an outer surface defining a space between the outer surface of the inner balloon and the inner surface of the outer balloon, a catheter having a first lumen in fluid communication with the space between the inner balloon and the outer balloon for supplying the agent thereto, and a second lumen through which fluid is supplied to the inflation chamber for inflating the inner balloon to urge the agent out of the opening in the outer balloon, wherein the outer balloon and/or the inner balloon comprise at least one protrusion for directing the agent. | 09-06-2012 |
20120310159 | LOCALIZED DELIVERY OF DRUG AGENTS - Medical devices including a substrate that are expandable from a compressed state to an expanded state; a coating on the substrate, the coating having a drug agent incorporated therein; and a sheath over the coating. The sheath is expandable from a compressed state to an expanded state and has at least one perforation therein. The medical devices are configured such that when the substrate is in a compressed state, the sheath is also in a compressed state and the perforation is substantially closed. When the substrate is in an expanded state, the sheath is also in an expanded state and the perforation is substantially open. The invention also includes a method of using the medical devices for the controlled, localized delivery of a drug agent to a target location within a mammalian body. | 12-06-2012 |
20130218077 | LOCAL DELIVERY WITH A BALLOON COVERED BY A CAGE - A catheter configured for delivering an agent to a patient's vessel wall is described. The catheter includes an inflatable balloon substantially covered by a expandable cage such that when the inflatable balloon is inflated the expandable cage substantially surrounds an outer surface of the inflated balloon. The inflatable balloon is configured to be deployed within a lumen against a lumen wall and separated from the lumen wall by the expandable cage in an expanded state, and is adapted to provide an agent delivery to a treatment site, and the expandable cage is further collapsible and is removable from said lumen. | 08-22-2013 |
20130237909 | BALLOON CATHETERS HAVING A PLURALITY OF NEEDLES FOR THE INJECTION OF ONE OR MORE THERAPEUTIC AGENTS - There are disclosed apparatus and methods for treating tissue by delivering at least one therapeutic agent into the tissue. In one embodiment, the apparatus comprises a catheter and a balloon member disposed on a distal region of the catheter. A plurality of pockets are disposed on the balloon member, and a plurality of needles are associated with each of the plurality of pockets. The plurality of needles are configured to engage tissue when the balloon is in the inflated state, and further are configured to disperse a therapeutic agent from an associated pocket into the tissue when the balloon is in the inflated state. A first needle of the plurality of needles may comprise a length that is different than a second needle, permitting the delivery of first and second therapeutic agents to different depths within the tissue. | 09-12-2013 |
20130245552 | VASCULAR MEDICAL DEVICES WITH SEALING ELEMENTS AND PROCEDURES FOR THE TREATMENT OF ISOLATED VESSEL SECTIONS - Devices for the isolation of a selected portion of a vessel are described. In some embodiments, the device comprises an introducer sheath and a sealing catheter that are movable relative to each other to create an isolated volume with adjustable size and location. The methods for the treatment of vascular aneurysms using the devices are described. The treatment is achieved through the delivery of an effective amount of stabilization agent to an isolated volume that encompass the aneurysm. The device optionally has an aspiration means to improve the effectiveness of the treatment. | 09-19-2013 |
20130303982 | DRUG ELUTING BALLOON FOR THE TREATMENT OF STENOSIS AND METHOD OF MANUFACTURING THE BALLOON - A drug eluting angioplasty balloon ( | 11-14-2013 |
20140163467 | Enhanced System And Method For Wound Track Navigation And Hemorrhage Control - An internal compression tourniquet catheter system and method for wound track navigation for controlling hemorrhage from wounds. The preferred embodiments include an inflatable member constructed of thin, flexible and puncture resistant material such that when deflated can be wrapped around the catheter shaft, which passes within and has a lumen to inflate it. The inflatable member is of large potential volume enabling full inflation with near zero internal pressure when unconstrained externally. When positioned within a wound track and inflated, the gas or liquid injected into the balloon lumen creates pressure because its expansion is constrained by the tissues of the wound, and that pressure is transmitted directly to the surrounding tissue of the wound track. | 06-12-2014 |
20140296780 | POLYMER COMPOSITE CARBON NANOTUBE MICRONEEDLE DEVICES AND THEIR FABRICATION - Composite CNT microneedle fabrication and finally-constructed delivery device embodiments are described. The microneedles can provide a self-administered, painless alternative to standard hypodermic injection. | 10-02-2014 |
20140336575 | FRONTAL SINUS SPACER - Substance delivering spacer devices may comprise expandable reservoirs that are implantable in paranasal sinuses and other cavities, openings and passageways of the body to maintain patency and to provide sustained local delivery of a therapeutic or diagnostic substance. Delivery apparatus including elongate tubular members as well as shapeable distal portions and atraumatic tips are provided. Also provided are sinus penetrator devices and systems for performing ethmoidotomy procedures or for creating other openings in the walls of paranasal sinuses or other anatomical structures. | 11-13-2014 |
20160045717 | CATHETER BALLOON PROVIDED WITH MICROBOREHOLES AND A METAL MESH - The present invention relates to a balloon catheter having a catheter balloon with micro drillings and a metal mesh and particularly to balloon catheters for the cardiac field for minimizing or preventing restenosis. Active agent solutions may be administered through the micro drillings such as using an injection catheter. | 02-18-2016 |