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Material introduced or removed through conduit, holder, or implantable reservoir inserted in body

Subclass of:

604 - Surgery


604048000 - Treating material introduced into or removed from body orifice, or inserted or removed subcutaneously other than by diffusing through skin

Patent class list (only not empty are listed)

Deeper subclasses:

Class / Patent application numberDescriptionNumber of patent applications / Date published
604181000 Means moved by person to inject or remove fluent material to or from body inserted conduit, holder, or reservoir 1119
604264000 Body inserted tubular conduit structure (e.g., needles, cannulas, nozzles, trocars, catheters, etc.) 1080
604131000 Treating material forced into or out of body by self-acting fluid pressure, motor-driven, or mechanical energy storing means (e.g., pressure infusion or aspiration, etc.) 701
604960010 Having means inflated in body (e.g., inflatable nozzle, dilator, balloon catheter, occluder, etc.) 530
604164010 Body piercer, obturator rod, or stylet axially movable within body entering conduit while latter is disposed in body 503
604174000 Means for securing conduit to body 428
604246000 Means for controlling material flow to or from body, or metering a predetermined dose or amount 274
604950010 Conduit with self-propelled or remote control means 202
604110000 Having means for preventing reuse of device 163
604113000 Having means for cooling or heating body, treating or collected material or device 80
604173000 Injection or aspiration device having plural body entering conduits 80
604263000 Removable cover or protector for body inserted conduit 77
604288010 Implantable reservoir having access port implanted under skin 60
604122000 Having means for eliminating and/or preventing injection of air into body 59
604111000 Having means for indicating device is defective , used, or tampered with 56
604117000 Having structure for controlling depth of insertion of body piercer 49
604257000 Liquid reservoir with body inserted nozzle or feed conduit connected therewith 37
604118000 Having means for varying, regulating, indicating, or limiting injection pressure or aspirating suction 36
604244000 Means broken, cut, pierced, or torn to permit material flow to body 35
604116000 Having means for locating or identifying point where body is to be pierced (e.g., apertured body fitting template, etc.) 34
604171000 Body entering conduit axially movable within flexible protective sheath facilitating sterile insertion into body duct 33
604285000 Treating material insert retained in body orifice 21
604158000 Body entering conduit axially movable within body piercing conduit while former is disposed in the body 20
604104000 Having means expanding body orifice or canal (e.g., dilator, retaining means, etc.) 18
604112000 Having means for desensitizing skin 9
604115000 Having means for protruding skin to facilitate piercing it 8
604156000 Conduit forced into body by self-acting fluid pressure, motor-driven, or mechanical energy storing means 8
604288040 Implantable reservoir having inlet or outlet 7
604940010 Dual nozzles for insertion into paired body orifices (e.g., nasal passages, etc.) 5
20110288476Systems and methods for nasal lavage - A nasal lavage device includes a source of saline solution, an effluent receptacle, and a nasal interface for engaging the nostrils of a user of the device. A fluid passageway is disposed to communicate the source of saline solution with the effluent receptacle through the nasal cavity of the user. The nasal interface and fluid passageways are included within a removable cartridge for communicating the saline relative to the nostrils in a first direction. A second cartridge can be inserted to communicate the flow in a second direction. The interface includes nasal pillows that form a seal against the user's nostrils.11-24-2011
20090062733Nasal Insert Device - Inter-nasal delivery devices are disclosed. The inter-nasal delivery devices can include a first nasal element and a second nasal element that are configured to be inserted into adjacent nostrils. In one embodiment, the nasal elements can have a tubular shape. In one embodiment, a sinus relief composition that emits vapors that are to be inhaled by the user can be positioned on the inside surfaces of the nasal elements. Sinus relief composition can be applied to the inside surface without block an open passageway through each nostril. In an alternative embodiment, a pharmaceutically active compound can be applied to exterior surfaces of the nasal elements for absorption through nasal tissue. In still another embodiment, the nasal elements can have a panel-like shape as opposed to a tubular shape.03-05-2009
20120078173Systems and methods for nasal irrigation - Systems and methods for nasal irrigation are provided in which a nasal irrigation device includes a source of saline, an effluent receptacle, a nasal interface, a vacuum source, a fluid passageway to communicate the source of saline with the effluent receptacle through the nasal interface and a nasal cavity of the user, and a switch and valve assembly for selectively controlling the vacuum source and flow of the saline solution through the fluid passageway. The saline source is disposed relative to the device to provide gravitational inducement of saline to the nasal interface in engagement to the device user's nostrils. A combination of the gravitational inducement and the relative vacuum from the effluent receptacle generates a fluid flow for irrigating, cleansing and massaging the nasal cavity and ostia of a user. The entire device is assembled as a hand-held device for convenient lifting and disposal against the user's nostrils.03-29-2012
20100152653Systems and methods for nasal lavage - A nasal lavage device includes a source of saline solution, an effluent receptacle, and a nasal interface for engaging the nostrils of a user of the device. A fluid passageway is disposed to communicate the source of saline solution with the effluent receptacle through the nasal cavity of the user. The nasal interface and fluid passageways are included within a removable cartridge for communicating the saline relative to the nostrils in a first direction. A second cartridge can be inserted to communicate the flow in a second direction. The interface includes nasal pillows that form a seal against the user's nostrils.06-17-2010
20130158475Devices for Delivering a Medicament and Connector for Same - A method and device for delivering medicament such as for ameliorating pain in a patient from an injector superiorly and/or laterally and/or anteriorly towards the sphenopalatine ganglion (SPG). A device for delivering a medicament to a patient in need thereof includes (a) an injector containing a first end configured to remain outside a nasal passage of the patient and a second end configured for entry into the nasal passage of the patient; and (b) an introducer configured for engagement with a nostril of the patient and containing a passageway configured for slidably receiving the injector. The injector is moveable between a storage position preceding the engagement and an engaging position pursuant to the engagement. The device may further include a locking connection assembly that is useful in other devices.06-20-2013
20130030361COATED MEDICAL IMPLANT - The present invention relates to a coated medical implant wherein the coating comprises an amorphous Me oxide layer or an (Al, Me) oxide layer deposited by physical vapor deposition, and wherein Me can be one or more of the elements of Ti, Si, Cr, Hf, Zr, Ta or Nb. The PVD layer does not have any bioactive/osseointegrating properties at temperatures below 45° C. This makes it easy to remove the implant after it has being inserted in an animal or human body, e.g. when used for fixating fractures. The coating may further comprise a calcium phosphate layer, preferably a hydroxyapatite layer, which is grown on the PVD layer using a biomimetic process. The coating may be loaded with a releasable agent such as a pharmaceutical agent, an ion or a bio molecule. The present invention also relates to a method for forming the coated medical implant.01-31-2013
20130030360Implantable Devices Including A Mesh And A Pivotable Film - The present disclosure relates to implantable medical devices which include at least one mesh and at least one film pivotably attached to the mesh.01-31-2013
20100160857Hand-Held Electronically Controlled Injection Device For Injecting Liquid Medications - A medication delivery device includes a housing, a door coupled to the housing and moveable between a closed position and an open position. The door permits insertion of a medication container, containing liquid medication, into the housing in the open position. A door opening mechanism is coupled to the door. A push member is axially moveable between a retracted position and a non-retracted position and located external to the medication container. The push member enters the medication container and pushes the liquid medication out of the medication container. A lock mechanism is coupled to the door opening mechanism and prevents opening of the door when the push member is in the non-retracted position inside the medication container, wherein the lock mechanism automatically unlocks the door opening mechanism when the push member is in the retracted position.06-24-2010
20110196295DEVICE AND METHOD FOR INTRA-BRONCHIAL PROVISION OF A THERAPEUTIC AGENT - The present invention includes an intra-bronchial device, system, and method for providing a therapeutic agent to a patient. A device includes a flow control member for placement in an air passageway communicating with a lung portion and when deployed in the air passageway inhibits a therapeutic agent distal of the control member from moving proximal of the control member, and includes the therapeutic agent associated with the flow control member. The control member may inhibit movement of the therapeutic agent by limiting airflow, and may include a one-way valve limiting exhalation of air from the lung portion. The control member may include a flexible membrane impervious to air flow, or a separator arranged to inhibit the movement of the therapeutic agent. The control member may include at least one anchor, and the anchor may be releasable from the air passageway for removal of the intra-bronchial device.08-11-2011
20090177150Low Friction Systems and Devices - Disclosed herein are compositions and systems having a low coefficient of friction. The low friction system comprises a first surface and a second surface, where the first surface comprises (i) a polycarbonate and a first additive, or (ii) a poly-butylene terephthalate and a second additive; and the second surface comprises a polyoxymethylene and a third additive. The low friction compositions and systems are valuable for producing devices, such as medical devices.07-09-2009
20100042045STERILE APPLIANCE DELIVERY DEVICE FOR ENDOSCOPIC PROCEDURES - A surgical device comprising a container and a tether used for delivering a sterile appliance into a body cavity during endoscopic procedures. Once positioned in the body cavity, a force is applied to the container through the tether. The force opens the container and releases the sterile appliance into the body cavity. In various embodiments, gas or liquid may be used to open the container.02-18-2010
20130046235Devices and methods for recording information on a subject's body - Embodiments disclosed herein relate to methods, devices, and computer systems thereof for visibly or non-visibly indicating a subject has received a medical treatment. In certain embodiments, a subject receives an information mark in conjunction with a medical treatment. In certain embodiments, the information mark includes unique information relating to the subject. In certain embodiments, devices, computer systems, and methods relate to reading an information mark on a subject, and optionally determining if further medical treatment of the subject is warranted. In certain embodiments, receipt of an information mark entitles a subject to a reward.02-21-2013
20130090597USE OF MODIFIED HOLLOW FIBER MATERIALS FOR REMOVING EXOTOXINS PRODUCED BY ESCHERICHIA COLI FROM LIQUIDS AND METHODS FOR TREATING CONCOMITANT DISEASES - The present invention relates to chemically modified hollow fiber materials for extracorporeally removing exotoxins produced by pathogenic Escherichia coli from protein containing liquids, particularly from blood or plasma, as well as the use in treating patients suffering from diseases which, for example, are caused by enterohemorrhagic 04-11-2013
20110009817INTRAVENOUS FLUID MONITORING - Apparatus, systems and methods related to monitoring intravenous fluids during administration to a subject are disclosed. These apparatus, systems and methods provide near real-time monitoring of the identity of one or more components of an intravenous fluid.01-13-2011
20090270799FLUID INJECTION DEVICE - A fluid injection device includes: a fluid injection unit having; a fluid chamber body in which a fixed face, a diaphragm facing the fixed face, a fluid chamber having a space surrounded by a side wall continuing the fixed face and the diaphragm, and an inlet channel tube and an outlet channel tube communicating with the fluid chamber are integrally molded; an actuator in close contact with the diaphragm; and a lid body holding the fluid chamber body, wherein inner surfaces of respective connecting parts of the fixed face, the side wall, and the diaphragm are rounded in molding, and a volume of the fluid chamber is reduced by the diaphragm, and a pulsating fluid is injected from a nozzle opening provided in an end direction of the outlet channel tube.10-29-2009
20130066265INFUSION PUMP ASSEMBLY - An infusion pump assembly includes a locking tab and a pump barrel inside a pump barrel housing, the pump barrel accommodates a reservoir assembly. The reservoir assembly includes a reservoir and a plunger rod. The infusion pump assembly also includes a locking disc at a terminus of the pump barrel. The locking disc includes a clearance hole for the plunger rod. The locking disc also includes at least one locking tab notch in close proximity with the locking tab. The locking tab is in moveable engagement with the locking tab notch, and the reservoir moves the locking tab from a locked position to an unlocked position when the plunger rod is inserted through clearance hole. The locking disc rotates upon torque being applied to the reservoir assembly, the locking disc rotating from a non-loaded position to a loaded position with respect to the plunger rod and a drive screw.03-14-2013
20110021983Method and Apparatus for Patient-Controlled Medical Therapeutics - An apparatus and associated methods are provided to authenticate a patient based on a biometric identifier of the patient before a prescribed dose of medical therapeutic, such as analgesics or other medication, are dispensed to the patient. Authentication takes places by pressing a button and scanning the patient's fingerprint and recording data corresponding to the fingerprint into memory. To receive the medical therapeutic, the patient can have his or her fingerprint read and compared to the stored fingerprint. If there is a match and the programmed limitations are met (e.g., a time interval has elapsed since the last dose), then the medical therapeutic is automatically dispensed to the patient. The system may be integrated with a new patient-controlled medical therapeutic device or the system may be added to an already existing device. Other features and advantages of the example embodiments are described.01-27-2011
20120116302RESERVOIR FILLING SYSTEMS AND METHODS - A reservoir may be filled with fluidic media in a first type of environment, a plunger head may be placed within the reservoir in the first type of environment, and a casing that may be configured to envelop at least a portion of a plunger arm operatively connected to the plunger head may be attached adjacent to at least a portion of the reservoir in a second type of environment. A reservoir may be provided having a first and second portion for respectively containing fluidic media, the second portion may be adapted to be removable, the reservoir may be selectively filled with a first volume or a second volume of fluidic media, a seal member may be placed in the reservoir, and the second portion may be removed in a case where the reservoir contains the first volume of fluidic media.05-10-2012
20090234277DELIVERY SYSTEM - A covering for delivering a substance or material to a surgical site is provided. The covering, with substance provided therein, may be referred to as a delivery system. Generally, the covering may be a single or multi-compartment structure capable of at least partially retaining a substance provided therein until the covering is placed at a surgical site. Upon placement, the covering may facilitate transfer of the substance or surrounding materials. For example, the substance may be released (actively or passively) to the surgical site. The covering may participate in, control, or otherwise adjust, the release of the substance.09-17-2009
20080294101Body-Insertable Apparatus and Manufacturing Method Thereof - A body-insertable apparatus which can make the volume smaller by simplifying a mechanism taking in or throwing out predetermined fluid is realized. The body-insertable apparatus has a configuration having, in a housing, a balloon member, a communication adjusting mechanism, a control circuit, and a power source part and forms a storage chamber by the balloon member and an outer circumferential member (sheet holding substrate and part of the housing) covering the outer surface of the balloon member. In the body-insertable apparatus, a first communication pipe communicated with the inner space of the balloon member and a second communication pipe communicated with the outer space are formed. The communication adjusting mechanism communicates the first communication pipe with the second communication pipe based on an electric current output from the control circuit. The inner space of the balloon member is communicated with the outside of the body-insertable apparatus. The outside fluid is flowed into the storage chamber via an inlet with the contracting operation of the balloon member.11-27-2008
20110106006IMPLANTABLE DEVICE FOR LONG-TERM DELIVERY OF DRUGS - A device for sustained delivery of a poorly water soluble drug is described. A drug reservoir within the device, when in operation, contains an aqueous suspension of the drug mixed with a suspension of an excipient that, in one embodiment, generates acidic groups for a sustained period of time to maintain a desired pH in the aqueous suspension that in turn provides a constant concentration of a soluble form of the drug.05-05-2011
20110301535MICROFLUIDIC CONTROL SYSTEMS - The present invention relates to microfluidic devices. In particular, the present invention relates to microfluidic devices for performing spatio-temporal operations and applications thereof.12-08-2011
20120109055Disposal Chain Supply Systems Method And Apparatus - This patent application teaches methods and apparatus of an efficient disposal chain system which includes a process of receiving fluid enclosing containers, transforming said containers into collection containers by integrating said containers into vacuum canister collection systems. Such a collection system includes a remote vacuum source configured to draw a vacuum force away from said container and towards said container. Such a vacuum source is configured to draw room air. Such a force is configured to draw waste materials along a path towards said collection container. A transformation of said containers includes deriving said containers from supply chains and transforming said containers into said collection systems at least in part by supporting said containers inside said canisters from below utilizing various configurations of measurement stands, said stands configured to support and accommodate various sizes, types and shapes of said containers.05-03-2012
20110082421Receptor-Based Blood Detoxification System - The invention discloses compositions of matter and methods of using such compositions to detoxify blood and blood products. The invention as particular use in the treatment of diabetes, Alzheimer's disease, hemodialysis associated amyloidosis, and cardiovascular complications.04-07-2011
20090012466Terminal Sterilization of Prefilled Containers - A method for inhibiting adverse reaction of the contents of a prefilled container during a radiation sterilization procedure is disclosed. In the method, a container which is made of a material including a radiation stable polyolefin is prefilled with a medium prior to being subjected to a gamma irradiation sterilization treatment. By using a radiation stable polyolefin material as the container, such as a polyolefin with a radiation stabilizer additive, and by prefilling the container prior to the gamma irradiation treatment, the container can be effectively sterilized without adversely affecting its contents.01-08-2009
20100125243APPARATUS AND METHODS FOR SUPPORT OF A MEMBRANE FILTER IN A MEDICAL INFUSION SYSTEM - A removable clamp, for supporting a membrane filter in a medical infusion system, includes connected and opposing walls. A locking feature, which may be connected to an end of one of the walls, engages and disengages a terminal end of the other wall. The filter may be inserted between the opposing walls of the clamp, and an inner surface of each of the opposing walls may be secured against corresponding major surfaces of the inserted filter, by only pressing at least one of the opposing walls of the clamp toward the other of the opposing walls.05-20-2010
20090306586LATERALLY-EXPANDABLE ACCESS CANNULA FOR ACCESSING THE INTERIOR OF A HIP JOINT - A laterally-expandable access cannula comprising: 12-10-2009
20120109054DEVICES WITH AN ERODIBLE SURFACE FOR DELIVERING AT LEAST ONE ACTIVE AGENT TO TISSUE OVER A PROLONGED PERIOD OF TIME - A device is disclosed for delivering an active agent to target tissue at a site that includes a bodily fluid. The device includes a body that has an erodible member that releases the active agent over a prescribed period of time.05-03-2012
20110270168RELEASING DEVICE FOR ADMINISTERING A BIO-ACTIVE AGENT - A releasing device for administering a bio-active agent to a human, animal, or plant is described herein. The device comprises a core of a solid organic matrix, in which a bio-active agent is contained. A metallic layer surrounds the core to form an outer shell, and at least one aperture is present in the metallic layer for controlled release of the bio-active agent to the patient. Optionally, a third, polymeric, ceramic or organo-ceramic layer is provided, and may be loaded by bioactive agent as well.11-03-2011
20120271230Fibroid Treatment System and Method - Various embodiments of a fibroid treatment system and method are provided. Embodiments are adapted to treat fibroids utilizing by blocking or impeding blood flow through the uterine artery to prevent growth of the fibroid. Additionally, drugs or therapeutic agents can be included to further shrink or starve off the fibroid to provide a secondary mode of action.10-25-2012
20090299279OPTICAL DETERMINATION OF THE POSITION OF THE STOPPER IN GLASS AMPOULES - This invention relates to a method for determining the stopper position of a medicament cartridge in a medical apparatus by means of a light source and photosensitive sensor surface.12-03-2009
20130218075DEVICE FOR IRRADIATING AN INTERNAL BODY SURFACE - An implantable apparatus for internal treatment of body cavities and damaged vessels using electromagnetic radiation having an implantable light source is operationally connected to an implantable illuminating surface. The implantable light source and implantable illuminating surface are of materials, which are compatible with implantation in a human subject, and possessed of an expanded, deployed configuration and compact, undeployed configuration suitable for laparoscopic insertion within a body cavity for application, when deployed, to an outer, periadventitial surface of an internal vessel or surface of an organ. The apparatus also has a control unit, which control unit regulates the activation of said light source and is optionally located remotely from the implantable light source and illuminating surface.08-22-2013
20120296271WIRELESS REMOTE NEUROSTIMULATOR - A therapy system includes a therapy module implantable within a mammalian body that provides a given therapy and a control module implantable within the mammalian body that effects the therapy provided by the therapy module. The control module is physically separate from the therapy module.11-22-2012
20090082721Systems and methods for applying a selected treatment agent into contact with tissue to treat sphincter dysfunction - Systems and methods apply a selected treatment agent or agents into contact with tissue at or in the region of a dysfunctional sphincter (in the case of GERD, fecal incontinence, or other dysfunctional sphincter disorders) to affect improved sphincter barrier function and/or to disrupt abnormal nerve pathways. The treatment agent can include at least one cytokine and/or at least one tissue bulking agent and/or at least one vanilloid compound to evoke a desired tissue response. The systems and methods can be used a primary treatment modality, or applied as a supplementary treatment before, during or after a primary intervention.03-26-2009
20120197188METHODS AND APPARATUS FOR DRUG MODELING AND DISPLAYING DRUG MODELS - Drug delivery models, displays, and systems may be configured to provide a clinician with readily intuitive information about the effects of one or more drugs on a subject. Interactive features may be included to provide a subject-specific model of the expected or predicted effects of one or more drugs on the subject. Additionally, interactive features that effect drug delivery to the subject may also be included. Drug delivery models, displays, and systems may be used in teaching, in advance of treatment, during treatment, or following treatment.08-02-2012
20110144575METHOD AND APPARATUS FOR MINIMIZING POST-INFARCT VENTRICULAR REMODELING - A cardiac rhythm management device for in which pre-excitation pacing is applied to one or more sites in proximity to an infarcted region of the ventricular myocardium. Such pacing servers to either prevent or minimize post-infarct remodeling.06-16-2011
20090209906SELF-SEALING DEVICE AND METHOD FOR DELIVERY OF A THERAPEUTIC AGENT THROUGH A PNEUMOSTOMA - A pneumostoma management system includes a pneumostoma management device for maintaining the patency of a pneumostoma and a drug delivery device for pneumostoma care. The drug delivery device may be used to introduce therapeutic agents into the pneumostoma for direct treatment of the pneumostoma, treatment of the lung by way of collateral ventilation, and/or treatment of non-lung tissues by diffusion into the bloodstream. The drug delivery device includes a therapeutic agent dispenser for supplying a therapeutic agent and a propellant at positive pressure, an outlet and a connector for correctly positioning the outlet relative to a pneumostoma management device. The drug delivery device includes a self-centering and self-sealing connector for engaging the pneumostoma management device.08-20-2009
20080262421RETRACTABLE FLUID COLLECTION DEVICE - Retractable medical device including a body having an open back end and a front end. A movable member is arranged within the body. The movable member has a back end and a front end. A needle holding member is arranged in an area of the front end of the movable member. A spring is structured and arranged to move the needle holding member to a retracted position within the movable member when the movable member experiences at least one of: the front end of the movable member is caused to expand generally radially; the back end of the movable member is caused to contract generally radially; the front end of the movable member is caused to expand generally radially when the back end of the movable member is caused to contract generally radially; and axial movement caused by a cap closing off the back end of the body which engages a tapered surface of the back end of the movable member. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way.10-23-2008
20120197189METHOD FOR PRODUCING AUTONOMOUSLY CONTRACTING CARDIAC MUSCLE CELLS FROM ADULT STEM CELLS, IN PARTICULAR HUMAN ADULT STEM CELLS - A method for producing autonomously contractile heart muscle cells by cultivating and differentiating stem cells obtained from differentiated exocrine gland tissue of an organism is described. Various uses of the heart muscle cells, in particular in regenerative medicine, are also described.08-02-2012
20100331775IMPLANTABLE SELF-POWERED BIODEGRADABLE MEDICAL DEVICE TO TREAT OR PREVENT REPERFUSION INJURY - In one embodiment, the present disclosure provides a biodegradable, self-powered medical device for preventing or reducing reperfusion injury, comprising a galvanic cell, the galvanic cell comprising: a first biodegradable electrode member; and a second biodegradable electrode member comprising a biodegradable conductive polymer and an electrode-releasable therapeutic agent, wherein the galvanic cell generates an electric force sufficient to cause the electrode-releasable therapeutic agent to be released from the biodegradable conductive polymer and elute to a target location. The device may further include a reservoir material containing a burst-release therapeutic agent.12-30-2010
20100069832Intelligent medical device system dynamics for biological network regulation - The intelligent medical device (iMD) system coordinates the dynamics of hardware and software components in a self-organizing autonomous system. The iMD system uses advanced modeling and metaheuristics to solve complex optimization problems involving the customization of medical therapies. The system uses evolvable hardware and reprogrammable features to coordinate the diagnostic and therapeutic functions of the iMDs.03-18-2010
20110098640VISUAL INDICATION OF RUPTURE OF DRUG RESERVOIR - The present disclosure relates to methods for visualizing the opening of a drug reservoir of an implantable medical device. In particular, the present disclosure provides methods for observing the release or exposure of contents from a drug reservoir of a medical device placed within the vitreous of an eye of a subject. The methods include implanting a drug delivery device within an anatomy of a subject. The drug device includes a plurality of reservoirs, each loaded with a therapeutic agent and a marker. Furthermore, the drug delivery device comprises a plurality of barrier layers for separating the contents of one of the plurality of reservoirs from the anatomy. The method further includes irradiating at least one of the plurality of barrier layers such that at least one of the plurality of reservoirs is breached, thereby triggering release of the therapeutic agent and the marker from the device. By visually detecting release of the marker into the anatomy, release of the therapeutic agent into the anatomy is verified.04-28-2011
20110071468Systems and methods for applying a selected treatment agent into contact with tissue to treat sphincter dysfunction - Systems and methods apply a selected treatment agent or agents into contact with tissue at or in the region of a dysfunctional sphincter (in the case of GERD, fecal incontinence, or other dysfunctional sphincter disorders) to affect improved sphincter barrier function and/or to disrupt abnormal nerve pathways. The treatment agent can include at least one cytokine and/or at least one tissue bulking agent and/or at least one vanilloid compound to evoke a desired tissue response. The systems and methods can be used a primary treatment modality, or applied as a supplementary treatment before; during or after a primary intervention.03-24-2011
20110071467PROBE FOR FLUID LEAK DETECTION WITH MULTIPLE LAYERS - A disposable medical probe for detecting a leak of physiological fluid comprising: a support layer, a conductive layer on top of the support layer, the conductive layer comprising two conducting electrodes both placed exclusively on each side of a longitudinal axis, a hydrophilic layer on top of at least a part of the conductive layer, where the conductive layer defines two zones: a proximal zone where two proximal electrode parts being are placed parallel to each other and being spaced apart by a distance d, and a distal zone where two distal electrode parts are symmetrical with respect to said longitudinal axis and are spaced apart from each other by a gap e greater than said distance d.03-24-2011
20120277670BURR HOLE CAP ASSEMBLY WITH THERAPY DELIVERY MEMBER ORIENTATION FEATURE - In some examples, a burr hole cap assembly includes one or more markers that indicate a rotational orientation of a therapy delivery member relative to the burr hole cap assembly, where the therapy delivery member extends through an opening defined by the burr hole cap assembly. In addition, in some examples, the burr hole cap assembly includes a feature that indicates the rotational orientation of the therapy delivery member after the therapy delivery member is implanted in the patient. The feature can include the one or more markers in some examples.11-01-2012
20110152759USE OF BIOMARKERS AND THERAPEUTIC AGENTS WITH SURGICAL DEVICES - Biomarkers are collected and used to determine biological propensities of a patient, to determine the efficacy of medical devices, to select and administer therapeutic agents, to select medical devices, to make adjustments to medical devices, and/or to adjust surgical techniques. An apparatus includes a port to draw a biological fluid (e.g., a mist) from a surgical site. The apparatus includes a sensor having a cantilevered beam. The beam includes substances selected to attract certain biomarkers as the fluid is communicated across the beam. The same apparatus or another apparatus is used to administer a therapeutic agent based at least in part on collected biomarker data. The therapeutic agent delivery apparatus may include a device that is also used to create a wound at a surgical site. For instance, a harmonic surgical instrument may be used to both collect biomarkers and administer a therapeutic agent (e.g., gene therapy using sonoporation).06-23-2011
20080214998Perfusion Device and Method - A perfusion device and method is provided. In one embodiment, the device includes a container having a first internal chamber configured to hold the material; a port for introducing the liquid into the chamber; a vent for releasing gas and liquid from the chamber; and a means for sealing the vent to allow a vacuum to be drawn on the first chamber The material may be biomaterial, such as a bone graft material in any form. In one embodiment, the container is a syringe that defines the internal material chamber and includes an end cap and a plunger The vent may be formed by a venting passageway in plunger and/or cap in some embodiments. In one embodiment, the vacuum may be created by a medical syringe coupled to the container, and which in some embodiments may also be used to deliver the liquid into the container The liquid may be bone marrow aspirate in some embodiments.09-04-2008
20100324481ULTRASOUND PUMPING APPARATUS FOR USE WITH THE HUMAN BODY - An apparatus utilizing ultrasonic vibrations to force the movement of protrusions to supply a liquid stream with sufficient velocity as to penetrate deep into treatment areas including body lumens, body cavities, and poorly perfused tissues at a pressure not harmful to the treatment area into which the liquid stream is injected is presented. The apparatus comprises an ultrasound horn with a dampening grommet attached to its distal end and an internal chamber. Within the internal chamber of the horn are protrusions extending into the chamber. Liquid to be expelled from the horn enters the internal chamber of the horn through at least one channel passing through a wall of the horn and leading into the chamber. After passing through the horn's internal chamber the liquid exits the horn by passing through a channel originating in the front wall of the chamber.12-23-2010
20120209173MATERIAL REMOVAL CATHETER AND METHOD - A catheter device and methods useable to extract material from a body conduit, e.g., a blood vessel, are provided. The catheter comprises a flexible catheter advanceable into the body conduit, an opening in a wall of the catheter in fluid communication with a material collection chamber, and a controllably arcuate segment near the distal tip of the catheter and the opening. The catheter may include a sliding member, located within a lumen of the catheter, used to move the material entering the catheter through the arcuate segment opening, into the material collection chamber and away from said opening. The catheter may include a single mechanism utilized to both generate a vacuum to cause material to enter the catheter at the arcuate segment opening and also cause the sliding member to travel, inside the catheter, moving material away from the opening and into the material collection chamber.08-16-2012
20110202000ANTI-AMYLOID BETA ANTIBODIES CONJUGATED TO SIALIC ACID-CONTAINING MOLECULES - Antibody complexes including anti-Aβ antibodies conjugated with a sialic acid-containing molecule show improved bioavailability with no significant adverse effects on binding to amyloid beta.08-18-2011
20100016791RESERVOIR BARRIER LAYER SYSTEMS AND METHODS - A system for delivering fluidic media may include a reservoir disposed within a housing, the reservoir having at least one wall bordering an interior volume for containing fluidic media, the wall being made of a material comprising a cyclic olefin copolymer, the wall for substantially preventing light from passing through the material of the wall. Fluidic media contained in the interior volume may be expelled through a fluid conduit.01-21-2010
20110112475IMPLANTABLE DELIVERY DEVICE - The invention relates to delivery devices and methods for providing more uniform delivery of agents such as drugs. In some embodiments, a delivery device is provided made of one or more implantable materials having predetermined agent-permeable and agent-impermeable regions and a reservoir containing one or more active agents, either alone or in an acceptable composition, as well as methods of administering one or more agents using such a device. Also provided are methods of equilibrating such devices, so that a steady state of agent delivery can be achieved at or soon after introduction of the device to its intended location of use. Methods of use of such devices to deliver an agent are also provided.05-12-2011
20120226226DEVICES, SYSTEMS AND METHODS FOR MEDICAMENT DELIVERY - An apparatus includes a label configured to be coupled to a medicament delivery device. The label includes a first surface and a second surface. The first surface is configured to be coupled to an outer surface of the medicament delivery device. The second surface includes a textual indicia. The label further includes an electronic circuit system configured to output an electronic signal.09-06-2012
20110125090OPHTHALMIC DRUG DELIVERY SYSTEM AND METHOD - An ocular device comprising a biodegradable, and absorbable body configured in a shape for implanting 05-26-2011
20100130922FLUID CONNECTION ASSEMBLY WITH LOCKING MECHANISM - In general, this disclosure relates to techniques for implementation and use of a fluid connection assembly, having a locking mechanism, which may be connected to a medical fluid injection device. An example fluid connection assembly includes at least one fluid connector, a mating mechanism coupled to the at least one fluid connector and configured to connect the at least one fluid connector to a medical fluid injection device, and a locking mechanism coupled to the mating mechanism and movable into a locked position or an unlocked position. In this example, the fluid connection assembly becomes affirmatively coupled with the medical fluid injection device when the locking mechanism is in the locked position, and the fluid connection assembly becomes removably decoupled from the medical fluid injection device when the locking mechanism is in the unlocked position.05-27-2010
20130023823IMPLANTABLE THERAPEUTIC DEVICE AND METHODS OF MAKING - The subject invention pertains to an implantable therapeutic device for treating diabetes and methods of making. Upon implantation, the present device secretes insulin in response to blood glucose levels, exquisitely regulates blood glucose levels, reduces hyperglycemia, and includes β-cell regeneration in the host. It is useful for treating or ameliorating diabetes or diabetic conditions of a subject, including but not limited to, type 1 diabetes mellitus, hyperglycemia, impaired glucose tolerance, insulin deficiency, elevated glucose levels, and insulin resistance.01-24-2013
20130096496LONG TERM DRUG DELIVERY DEVICES WITH POLYURETHANE BASED POLYMERS AND THEIR MANUFACTURE - This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects comprises: 04-18-2013
20130102959Implantable Film/Mesh Composite - The present disclosure relates to implantable medical devices which include at least one mesh and at least one film attached to the mesh along different portions of the mesh creating at least one aperture between the mesh and the film.04-25-2013
20100286607PATIENT STATUS SENSOR - Embodiments of a patient status sensor can be applied to a patient or trauma victim to provide a quick visual and/or audible indication of the patient's vital signs (e.g., respiration, heart rate, or other vital signs). Certain embodiments are configured as an adhesive patch that includes electrodes for measuring heart rate (and respiration in some implementations), a processor configured to perform calculations for determining one or more vital signs using information from the electrodes, and audible or visual indicators to communicate information about vital signs or patient status to a medical attendant. Certain embodiments include an access opening for providing intraosseous delivery of fluids to bone marrow (e.g., through sternal or long bone) and can be integrated or used with an intraosseous delivery system. Certain embodiments include wired or wireless components to communicate vital signs or patient status to an external monitoring device.11-11-2010
20100292638HEMOSTASIS SEAL - A hemostasis seal configured for use in a splittable hemostasis valve, hub, or introducer sheath to permit passage of a medical device therethrough. The seal provides a substantially fluid-tight seal around the medical device without causing excessive frictional resistance that would otherwise unduly restrict movement of the medical device through the seal. In one embodiment, the seal includes first and second resilient seal portions each having a contoured mating surface to provide a first fluid seal with respect to the medical device. The seal also may include one or more projecting portions and one or more mating receiving portions which interact to provide a second fluid seal with respect to the medical device.11-18-2010
20130190687IMPLANTABLE MEDICAL DEVICES HAVING DOUBLE WALLED MICROSPHERES - An implantable medical device including at least one double-walled microsphere containing an active agent, and a biodegradable polymer layer containing the at least one double-walled microsphere.07-25-2013
20130197431DRUG RELEASING COATINGS FOR MEDICAL DEVICES - The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent, an antioxidant, and an additive. In certain embodiments, the additive has a hydrophilic part and a drug affinity part, wherein the drug affinity part is at least one of a hydrophobic part, a part that has an affinity to the therapeutic agent by hydrogen bonding, and a part that has an affinity to the therapeutic agent by van der Waals interactions. In some embodiments, the additive is a liquid. In other embodiments, the additive is at least one of a surfactant and a chemical compound, and the chemical compound has one or more hydroxyl, amino, carbonyl, carboxyl, acid, amide or ester groups.08-01-2013

Patent applications in class Material introduced or removed through conduit, holder, or implantable reservoir inserted in body

Patent applications in all subclasses Material introduced or removed through conduit, holder, or implantable reservoir inserted in body