Class / Patent application number | Description | Number of patent applications / Date published |
604517000 | To or from the urogenital system | 26 |
20080281291 | Drainage/irrigation urethral catheter - A urethral catheter comprises an elongate tubular shaft having an open proximal end, a sealed distal end a single lumen therein that extends between the proximal and distal ends. A proximal portion of the shaft has a first outer diameter and a distal portion of the shaft has a second outer diameter smaller than the first outer diameter. A plurality of openings are provided in the distal shaft portion. The plurality of openings communicate between an outer surface of the shaft and the single lumen and extend longitudinally from a point near the distal end toward the proximal end. The plurality of openings are located along one side of the shaft and are oriented in a common plane that bisects a longitudinal axis of the shaft. The openings most distant from the distal end of the shaft have a diameter that is smaller than that of the openings closest to the distal end of the shaft. | 11-13-2008 |
20090149833 | Implantable Drug Delivery Device and Methods for Treatment of the Bladder and Other Body Vesicles or Lumens - An implantable medical device is provided for controlled drug delivery within the bladder, or other body vesicle. The device may include at least one drug reservoir component comprising a drug; and a vesicle retention frame which comprises an elastic wire having a first end, an opposing second end, and an intermediate region therebetween, wherein the drug reservoir component is attached to the intermediate region of the vesicle retention frame. The retention frame prevents accidental voiding of the device from the bladder, and it preferably has a spring constant selected for the device to effectively stay in the bladder during urination while minimizing the irritation of the bladder. | 06-11-2009 |
20090171317 | Self-Catheterization Device To Administes Compounds To The Bladder - Devices and methods for self catheterization and for instilling fluid into the bladder are disclosed. A catheter device is provided for inserting into the urethra of an individual by the subject him or herself for the purpose of instilling a therapeutic compound into the bladder. The catheter assembly includes a catheter that has an opening near the tip, a valve mechanism, and a reservoir at the opposite end from the tip. The catheter may be provided with separate channels for draining the bladder and instilling a therapeutic compound into the bladder. Methods for self catheterization and self-administration of a therapeutic compound into the bladder by a patient are disclosed. | 07-02-2009 |
20090240234 | CATHETER WITH BIOLOGIC ADHESIVE INJECTION PORTS AND METHOD OF INJECTING BIOLOGIC ADHESIVE THEREWITH - A catheter and method for draining a bladder and injecting a two part biologic adhesive is provided. The catheter has a tubular body extending between proximal and distal ends. A balloon is located adjacent the distal end with a first port extending between the proximal end and the balloon providing for inflation an deflation of the balloon. A second port extends substantially between the proximal end and the distal end for drainage. A pair of ports separate from one another and from the first and second ports extend between the proximal end and the balloon. The pair of ports are each arranged in fluid communication with separate openings located between the balloon and the proximal end to provide separate fluid flow paths for the separate components of the two part biologic adhesive between the proximal end and the openings. | 09-24-2009 |
20090259213 | INJECTION TUBE FOR JET INJECTION DEVICE - A non-metal, polymeric tubular device for delivering a therapeutic fluid to a treatment site within a patient. The non-metal, polymeric tubular device can be fabricated using suitable high strength polymers and in some versions can be reinforced through the inclusion of reinforcement materials or braiding. The non-metal, polymeric tubular device can be fabricated so as to have a burst strength exceeding at least about 2,000 psi. The non-metal, polymeric tubular device can be fabricated so as to have distention properties, wherein an orifice or jet port located at a distal end of the polymeric tubular device retains its shape and/or size without suffering swelling that can have a detrimental impact on a fluid jet used to deliver the therapeutic fluid at the treatment site. | 10-15-2009 |
20100152704 | Method for Intravesical Drug Delivery - Implant devices for intravesical administration and local drug delivery. The device has a body which includes a hollow tube formed of a biocompatible material; at least one reservoir in the tube which contains a drug; and one or more apertures through which the drug can be released. The device is configured for minimally invasive insertion into a body cavity, such as the bladder. The hollow tube may be elastomeric to permit the device to be elastically deformed from its initial shape into an elongated shape for passage through a catheter, where following such passage the device can return to or toward its initial shape to facilitate retention of the device in the body cavity. The body may have a narrow, elongated shape effective to permit insertion of the drug delivery device through a catheter without necessarily deforming the body, yet include flexible projections which effect retention within the body cavity. | 06-17-2010 |
20110015614 | NEEDLELESS INJECTION DEVICE COMPONENTS, SYSTEMS, AND METHODS - Described are needleless injection systems and methods that involve features including one or more of a tissue tensioner and a fitting that includes or attaches to a shaft, exemplary embodiments including: an elastic sleeve sized to fit under tension about the distal end of a flexible scope, such as an endoscope; a non-metal, polymeric tube-like device being optionally attached to the elastic sleeve for delivering a therapeutic fluid to a treatment site within a patient wherein the elastic sleeve may include an integral balloon (tissue tensioner) feature that can be used to position the injection orifice of the tube-like device proximate a treatment area. | 01-20-2011 |
20110152839 | Implantable Device with Intravesical Tolerability and Methods of Treatment - Intravesical devices are provided that are wholly deployable within the bladder of a patient in need of treatment and are well tolerated by the patient. The device may include an elastic body having a retention shape having (i) dimensions that provide intravesical mobility and that prevent voiding of the medical device through the urethra, and (ii) dimensions, buoyancy, or both, that exclude the medical device from entering the orifices of the ureters. The elastic body may exert a maximum acting force less than 1 N when compressed to a shape with a maximum dimension in any dimension of 3 cm. The device may include a drug for controlled release within the bladder, for treatment of the bladder or a regional tissue. Methods of treatment are also provided that include selecting a patient in need of treatment in the bladder where tolerability of the treatment is a primary concern. | 06-23-2011 |
20120089121 | Implantable Drug Delivery Device with Bladder Retention Feature - Implantable devices and methods for controlled drug delivery are provided. The device includes a device structure deformable between a retention shape and a low profile shape for deployment in the bladder of a patient and has a drug reservoir lumen in which a drug formulation is housed. The device also includes a buoyancy retention portion, which includes a volume of entrapped air or a gas-generating or effervescent powder Which will generate a volume of entrapped air following contact with urine in the bladder. The buoyancy retention portion may include a water permeable and/or biodegradable wall, which can release the entrapped air following drug release, to cause the device to sink into the bladder neck to facilitate device expulsion without the need for a device retrieval medical procedure. | 04-12-2012 |
20120089122 | TIME-SELECTIVE BIORESORBABLE OR COLLAPSIBLE DRUG DELIVERY SYSTEMS AND METHODS - Implantable medical devices and treatment methods are provided, particularly for use in the bladder. The device is configured for retention in the bladder for at least a portion of the drug delivery period and includes at least one biodegradable component such that following a biodegradation at a selected time, the retention function is lost and the device or portions thereof are resorbed and/or excreted. The method may include deploying into the bladder of a patient a device having a device structure housing a drug formulation comprising at a drug; releasing drug from the device structure into the bladder; and then, changing the composition of urine in the bladder, e.g., by altering the pH, to trigger degradation of at least part of the device structure to enable the device structure or parts thereof to be excreted from the bladder. | 04-12-2012 |
20120203203 | IMPLANTABLE DEVICE FOR CONTROLLED DISSOLUTION AND DIFFUSION OF LOW SOLUBILITY DRUG - Implantable drug delivery devices are provided that are deformable between a relatively straightened shape suitable for deployment and a retention shape suited to retain the device within the bladder or other body cavity. While in the body cavity, the devices release drug from solid drug units housed in the devices. The devices are designed to house the solid drug units in a way that exposes one or more sides of the solid drug units to the fluid at the in vivo site of deployment. Methods for using the devices for administering drug and making the devices also are provided. | 08-09-2012 |
20130138083 | Catheter Devices and Techniques - This application describes example antimicrobial compositions that may be used alone or in combination with catheters and catheter insertion sites. According to another aspect, the application describes catheters which may employ one or more protection devices, such as cleaning caps, protective caps or both. | 05-30-2013 |
20130144265 | SURGICAL INSTRUMENT FOR INJECTING A DRUG INTO PROSTATE TISSUE - Method and surgical instrument for treating prostate tissue including a surgical instrument having a main body, a needle deployment port, a needle, first and second handles and a lockout release mechanism to limit needle extension. Additionally, a kit includes the surgical instrument, together with a cystoscope, and optionally a syringe and reservoir of ethanol. The method includes needle-less injection and visualizing the ethanol injection by delivering both an echogenic agent and ethanol either by needle or needle-less injection or by providing an ultrasonically visible marker near the tip of the ethanol delivery cannula. The method also includes extending the needle transversely of the instrument housing using a link assembly. | 06-06-2013 |
20130253476 | BLADDER DRUG ELUTING DEVICE - A drug delivery system that can be deployed from a catheter and retained within the bladder for delivery of treatment drug solutions over a period of time. The delivery system includes an inflatable or expandable delivery element that can be collapsed within the catheter tip for navigation into the bladder before being inflated or expanded within the bladder. The inflated or expanded delivery element can engage the bladder walls or sized to be too large to be passed from the bladder such that the delivery element is retained within the bladder after inflation or expansion to administer a treatment drug solution over an extended period of time. | 09-26-2013 |
20130253477 | BLADDER WALL DRUG DELIVERY SYSTEM - A catheter based drug delivery system for minimally invasive delivery of treatment drugs into a bladder wall. The catheter system can include a delivery tip for deforming the bladder wall before forming jets of drug solution that penetrate the bladder wall for needleless delivery of the treatment drugs directly to the diseased tissue. The delivery tip can also have graduated markings for providing visual indicators of the relative depth of the delivery tip in the bladder wall and the alignment of the formed jets with the particular layers of the bladder wall. | 09-26-2013 |
20130289529 | IMPLANT WITH HIGH VAPOR PRESSURE MEDIUM - An implant delivery system can be configured to deliver an inflatable implant into a bladder via a urethra. The delivery system can comprise an elongate tubular body, an inflation tube and an implant decoupler. The tubular body can comprise a central lumen configured to hold an inflatable implant in an initial un-inflated state for delivery of the implant into the bladder. A method of use can include passing a distal tip of the elongate tubular body into the bladder. The implant can be inflated and released into the bladder. | 10-31-2013 |
20140100551 | FLUSHING DEVICE AND A CATHETER KIT COMPRISING A FLUSHING DEVICE - A flushing device ( | 04-10-2014 |
20140221981 | IMPLANTABLE DEVICE WITH INTRAVESICAL TOLERABILITY AND METHODS OF TREATMENT - Intravesical devices are provided that are wholly deployable within the bladder of a patient in need of treatment and are well tolerated by the patient. The device may include an elastic body having a retention shape having (i) dimensions that provide intravesical mobility and that prevent voiding of the medical device through the urethra, and (ii) dimensions, buoyancy, or both, that exclude the medical device from entering the orifices of the ureters. The elastic body may exert a maximum acting force less than 1N when compressed to a shape with a maximum dimension in any dimension of 3 cm. The device may include a drug for controlled release within the bladder, for treatment of the bladder or a regional tissue. Methods of treatment are also provided that include selecting a patient in need of treatment in the bladder where tolerability of the treatment is a primary concern. | 08-07-2014 |
20140276634 | Access sheath - Disclosed is an assembly of parts for an endourological procedure including a tubular sheath and an introducer, the tubular sheath being removably mounted on the introducer. The tubular sheath includes a first and a second lumen of which the second lumen is openable to shift a guidewire from a position inside the second lumen to a position outside and next to the tubular sheath. Disclosed are also access sheaths and a method of performing an endourological procedure. | 09-18-2014 |
20140276635 | Access sheath - Disclosed is an assembly of parts for an endourological procedure, including a tubular sheath and an introducer, the tubular sheath being removably mounted on the introducer. The introducer comprises a security channel that is openable to shift a guidewire from a position inside the security channel to a position outside and next to the tubular sheath. Disclosed are also access sheaths and a method of performing an endourological procedure. | 09-18-2014 |
20140276636 | DRUG DELIVERY DEVICES WITH DRUG-PERMEABLE COMPONENT AND METHODS - Implantable drug delivery devices include a housing having a closed drug reservoir lumen bounded by a first wall structure and a hydrophilic second wall structure, and a drug contained in the drug reservoir lumen, wherein the first wall structure is impermeable to the drug and the second wall structure is permeable to the drug. Methods of providing controlled release of drug to a patient include deploying a drug delivery device in the patient releasing a drug from the drug reservoir lumen via diffusion through the second wall structure. | 09-18-2014 |
20150018802 | CATHETERIZATION APPARATUS AND METHODS THEREOF - A containing catheter for facilitating sequential treatment operations therethrough, is provided. The containing catheter comprises a median portion comprising an elongated, substantially tubular member, and a distal portion, comprising a distal stiff member. A catheterization apparatus is provided, comprising the containing catheter and an elongated inner catheter insertable into the containing catheter. A method of catheterization is provided, comprising providing the containing catheter, stiffening a portion of the containing catheter and inserting the stiffened containing catheter into a body conduit of a patient. | 01-15-2015 |
20150360011 | BLADDER DRUG ELUTING DEVICE - A drug delivery system that can be deployed from a catheter and retained within the bladder for delivery of treatment drug solutions over a period of time. The delivery system includes an inflatable or expandable delivery element that can be collapsed within the catheter tip for navigation into the bladder before being inflated or expanded within the bladder. The inflated or expanded delivery element can engage the bladder walls or sized to be too large to be passed from the bladder such that the delivery element is retained within the bladder after inflation or expansion to administer a treatment drug solution over an extended period of time. | 12-17-2015 |
20160008271 | DRUG DELIVERY DEVICES AND METHODS FOR DRUG DELIVERY | 01-14-2016 |
20160089014 | MEDICAL DEVICES AND RELATED METHODS OF USE - A medical device may include an insertion portion longitudinally extending between a proximal end and a distal end. The insertion portion may define a channel extending therethrough. The medical device may further include a handle coupled to the proximal end of the insertion portion. The handle may further include an irrigation port in fluid communication with the channel and coupled to a source of irrigation fluid. Additionally, the handle may include an actuator and a pressurizer. Manipulation of the actuator may be configured to actuate the pressurizer to urge irrigation fluid distally through the channel. | 03-31-2016 |
20160193456 | Methods for Intravesical Drug Delivery and Methods and Systems for Loading Devices with Drug Tablets | 07-07-2016 |