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Subclass of:

604 - Surgery

604019000 - MEANS FOR INTRODUCING OR REMOVING MATERIAL FROM BODY FOR THERAPEUTIC PURPOSES (E.G., MEDICATING, IRRIGATING, ASPIRATING, ETC.)

604048000 - Treating material introduced into or removed from body orifice, or inserted or removed subcutaneously other than by diffusing through skin

Patent class list (only not empty are listed)

Deeper subclasses:

Class / Patent application numberDescriptionNumber of patent applications / Date published
604506000 Therapeutic material introduced or removed through a piercing conduit (e.g., trocar) inserted into body 838
604503000 Therapeutic material introduced or removed in response to a sensed body condition 171
604514000 Therapeutic material introduced or removed from natural body orifice 167
604522000 Introduction of biologically derived compounds (i.e., growth hormones or blood products) including cells 77
604518000 Liquid therapeutic material administered with solid or second liquid 65
604501000 Enhanced absorption of therapeutic material internally using iontophoretic treatment 43
604521000 Therapeutic material to facilitate ocular treatment 12
604502000 Therapeutic material introduced by subcutaneous implant (e.g., peritoneal injectors) 10
Entries
DocumentTitleDate
20110184376LONG TERM DRUG DELIVERY DEVICES WITH POLYURETHANE-BASED POLYMERS AND THEIR MANUFACTURE - This invention is related to the use of polyurethane-based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs.07-28-2011
20130085470METHOD FOR PRESSURE-INDEPENDENT, REFILLABLE DRUG INFUSION DEVICE - Described is drug infusion device with one or more check valves for inhibiting the unintentional discharge of medication from a cartridge. The device includes a chamber capable of receiving a cartridge of medication in a fluid form and one or more novel check valves for ensuring the drug is not unintentionally released due to pressure differentials between the cartridge and the ambient pressure outside of the drug infusion device.04-04-2013
20130030406Textured Dilatation Balloon and Methods - The present disclosure provides a textured dilatation balloon that includes a balloon body having a proximal end, a distal end, and at least one indentation in the balloon body in an un-inflated state, wherein the balloon body comprises a continuous polymer tube with an external surface having at least one therapeutic agent disposed within the at least one indentation.01-31-2013
20130030408MRI SURGICAL SYSTEMS INCLUDING MRI-COMPATIBLE SURGICAL CANNULAE FOR TRANSFERRING A SUBSTANCE TO AND/OR FROM A PATIENT - A cannula for transferring a substance to and/or from a patient includes a tubular support sleeve and a transfer tube. The support sleeve includes a rigid tubular member defining a lumen extending from a proximal end to a distal end of the tubular member. The transfer tube is positioned in the lumen and extends beyond each of the proximal end and the distal end of the tubular member. The tubular member includes a rigid, MRI-compatible material.01-31-2013
20130030407Fluidic components, systems, and methods for use in ophthalmic surgeries - Fluidic components, systems, and methods for use in ophthalmic surgeries are disclosed. In some embodiments, a fluidics cassette for use with an ophthalmic surgical console system is provided. The fluidics cassette includes a housing, a fluid passageway extending through the housing, a membrane positioned in fluid communication with the fluid passageway such that a fluid passing through the fluid passageway contacts the membrane, and an opening extending at least partially through the housing such that the opening is in communication with the membrane and is configured to be coupled to a vacuum source. When the vacuum source is coupled to the opening, fluid passing through the passageway is subjected to the vacuum generated by the vacuum source through the membrane to remove dissolved gasses from the fluid.01-31-2013
20130030405INFRARED REFLECTIVE AIR-IN-LINE SENSOR SYSTEM - Air-in-line sensor systems and methods of using same are provided. In a general embodiment, the present disclosure provides an adapter including first and second cylindrical portions defining a fluid flow channel, the first cylindrical portion comprising two adjacent wedge-shaped protrusions. Each wedge-shaped protrusion is infrared transmittive and defines an outer surface and an inner surface. In another embodiment, an air-in-line sensor device includes a tube and an infrared reflective sensor having an infrared light emitter and an infrared light detector. The infrared light emitter and the infrared light detector are positioned at or near an adapter so that an infrared light can be transmitted to the adapter and at least a portion of the infrared light reflected off the adapter can be detected by the infrared light detector.01-31-2013
20100160892IMPLANTABLE SUCTION CUP COMPOSITES AND IMPLANTS COMPRISING SAME - Described herein are implantable composites, kits comprising the composites, implant devices comprising the composites, and methods of making and using same, including point of use methods.06-24-2010
20120179131IV PUMP ADAPTED FOR GENERIC TUBING - A system and method of accurately pumping a fluid using tubing of variable inner diameter and material is disclosed. The disclosed pump comprises a pumping mechanism configured to compress and release a portion of a flexible tube to cause fluid to flow along the flexible tube, a gauging apparatus, and a vacuum apparatus. The gauging apparatus is configured to determine the inner diameter of the flexible tube, which value is used in calibrating the pumping rate of the pump. The vacuum apparatus is configured to reduce the ambient pressure in a volume surrounding the portion of the flexible tube, thereby causing the flexible tube to fully expand to its original outside diameter when the flexible tube is released by the pumping mechanism.07-12-2012
20100114060System and method for controlling an implantable medical device subject to magnetic field or radio frequency exposure - A system for controlling an implantable medical device (e.g., a drug delivery device) susceptible to malfunctioning during exposure to a magnetic field and/or Radio Frequency field (e.g., during a magnetic resonance imaging procedure) and a method for operating the same. Exposure of the implantable device to the magnetic field and/or the Radio Frequency field is detected using the sensing device. When the detected magnetic field and/or Radio Frequency field exceeds a corresponding predetermined threshold level, an input signal is generated at the microcontroller. In response to the generated input signal, the microcontroller automatically triggers (i) a safety mode enabling a predetermined safety mode operation that alters some operation, without ceasing all operation, of the implantable medical device and/or (ii) after expiration of a predetermined safety mode time interval when the at least one field being detected falls below its corresponding predetermined threshold level or a predetermined period of time elapses, a self testing mode enabling a predetermined self testing operation to verify proper operation of the implantable medical device. Preferably, both the safety and self testing modes are automatically triggered.05-06-2010
20100114059SYSTEM AND METHOD FOR DELIVERY OF BIOLOGIC AGENTS - A delivery system for delivering a therapeutic agent to a patient includes a catheter, a stop feature, a container and a bar. The catheter has a proximal end and a distal end and includes a body defining a lumen that extends to the distal end of the catheter. The stop feature is in proximity to the distal end of the catheter. The container is configured to house the therapeutic agent and is insertable and slidably disposable in the lumen of the catheter. The container is also configured to engage the stop feature of the catheter. The bar is slidably disposable in the lumen of the catheter. Sliding of the bar distally in the lumen forces the therapeutic agent out of the container and out of the lumen when the container is engaged with the stop feature. The stop feature is configured to inhibit the container from exiting the lumen.05-06-2010
20120245555Blood tube section for extracorporeally carrying blood, extracorporeal blood circuit, treatment apparatus as well as methods - The present invention relates to a blood tube section for extracorporeally carrying blood during a blood treatment of a patient, wherein the blood tube section comprises at least one device for conveying blood, a drug solution or a liquid mixture within the blood tube section by deforming the tube diameter and sliding along an area of the blood tube section. The present invention further relates to an extracorporeal blood circuit, a treatment apparatus as well as methods for conveying blood, a drug solution or a liquid mixture and for supplying and/or administering and/or transporting an active substance.09-27-2012
20120245554Micro-Infusion System - Infusion systems according to the present invention provide a medical fluid infusion system operable at a relatively wide range of flow rates while simultaneously maintaining a high degree of accuracy and predictability through employing specific flow path architecture, flow path dimensional ranges, and pump control parameters, such as voltage, frequency, voltage rise time, pump size and quantity, and controlled restriction of the fluid flow path. Automatic recognition of restrictive elements is employed to facilitate the ease of use of different restrictive elements with a single infusion system and improve patient safety.09-27-2012
20130085468CATHETER WITH BODY WALL SEPARATOR - A catheter comprising a body wall separator for preventing the occlusion of catheter openings by body tissues when the catheter is placed in the body of a subject. The inventive catheter provides enhanced flow of fluids to and from the body. Methods of making and using the catheter, for drainage purposes for example, are also within the scope of the invention.04-04-2013
20100004621CHARGING MECHANISM FOR A NEEDLE FREE INJECTOR - The present invention provides a needle-free injector for delivering a medicament under pressure into an animal or human, the injector having a charging mechanism comprising a threaded shaft/nut member combination. The injection device is of the type that includes an actuating device comprising: a gas tight chamber; a piston and rod assembly slidably received in the chamber and movable between a forward position and a rearward position; a gas charge in the chamber for urging the piston and rod assembly to the forward position; a mechanism for moving said piston and rod assembly against said gas charge into the rearward position; and a trigger for releasably retaining the piston and rod assembly in the rearward position. Also provided is a method and kit for using the device including the charging mechanism to administer a liquid through the skin of an animal or human.01-07-2010
20130085469TAUROLIDINE FORMULATIONS AND DELIVERY: THERAPEUTIC TREATMENTS AND ANTIMICROBIAL PROTECTION AGAINST BACTERIAL BIOFILM FORMATION - Treating of localized bacterial infection, comprising locally applying Taurolidine to the infection. A device for insertion into the body, the device comprising Taurolidine to render the device infection resistant. A medication for treating bacterial infections, comprising Taurolidine carried by one of: gels, liquid, thixotropic gels, colloidal mixtures, dispensal suspensions, injectable polymers, or a microparticle. A method for treating blood, comprising: removing blood from the body; treating the blood with Taurolidine; and returning the treated blood.04-04-2013
20130079745METHODS AND SYSTEMS FOR GLUCOSE REGULATION - Various methods and apparatus for treating a condition associated with impaired glucose regulation in a subject comprising in one embodiment, applying a neural conduction block to a target nerve at a blocking site with the neural conduction block selected to at least partially block nerve pulses. In another embodiment, combinations of down-regulating and or up-regulating with or without pharmaceutical agents are used to treat impaired glucose regulation. In other embodiments, up-regulation or down-regulation of various nerves, such as the vagus and its branches, and the splanchnic is used to modify the production of GLP-1 and GIP, thereby controlling glucose levels. In yet further embodiments, combinations of down-regulating and or up-regulating with or without pharmaceutical agents are used to modify the production of GLP-1 and GIP, to treat impaired glucose regulation.03-28-2013
20100036360STENT GRAFT DELIVERY SYSTEM - A system for treating an aneurysm comprises an elongate flexible shaft and an expandable member. An expandable scaffold is disposed over the expandable member and may be expanded from a collapsed configuration to an expanded configuration. A double-walled filling structure is disposed over the scaffold and has an outer wall and an inner wall. The filling structure is adapted to be filled with a hardenable fluid filing medium so that the outer wall conforms to an inside surface of the aneurysm and the inner wall forms a substantially tubular lumen to provide a path for blood flow. In the expanded configuration the scaffold engages the inner wall of the filling structure. A tether is releasably coupled with the filling structure and the flexible shaft thereby constraining axial movement of the structures relative to each other.02-11-2010
20100145300METHODS AND APPARATUS FOR TRANSLATING A CONTINUOUS-DELIVERY DELIVERY PROFILE INTO A PLURALITY OF PERIODIC BOLUS DELIVERIES - Methods and apparatus for translating a continuous-delivery delivery profile into a plurality of periodic bolus deliveries.06-10-2010
20100145299Implantable Pump for Drug Delivery to Treat Erectile Dysfunction - An implantable pump (06-10-2010
20130035662INJECTABLE DRUG DELIVERY ARRANGEMENT WITH CONTROLLED DELIVERY CANNULA POSITION RELATIVE TO POINT OF DELIVERY - A cannula for administration of a medicine to a target location includes a tube with at least one nodule disposed along the circumferential surface and spaced at a defined distance from the distal end of the tube. An arrangement for delivery of a medicine to a target location includes the cannula and a pump fluidly coupled to the cannula. The distal end of the cannula may be inserted into a target location until the nodule reaches a surface that limits a depth of penetration before delivery of the medication.02-07-2013
20130035663Anticoagulant-Free Dialysis Systems And Methods - An extracorporeal blood treatment system includes means for withdrawing blood from a patient, and means for transporting the blood through a calcium trap. The calcium trap includes a substrate having an immobilized species, the species being adapted to reduce the calcium concentration in the blood to a concentration that prevents blood clotting in the extracorporeal blood treatment system, thereby producing calcium-depleted blood. The extracorporeal blood treatment system also includes means for treating the calcium-depleted blood downstream of the calcium trap by an extracorporeal blood treatment device, thereby producing treated calcium-depleted blood, means for infusing calcium into the treated calcium-depleted blood downstream of the extracorporeal blood treatment device to add calcium to the treated calcium-depleted blood, and means for returning treated blood back to the patient.02-07-2013
20130035660MULTIDIRECTIONAL MICROFLUIDIC DRUG DELIVERY DEVICES WITH CONFORMABLE BALLOONS - The methods, systems, and devices disclosed herein generally involve convection-enhanced delivery of drugs to a target region within a patient. Microfluidic catheter devices are disclosed that are particularly suitable for targeted delivery of drugs via convection, including devices capable of multi-directional drug delivery, devices that control fluid pressure and velocity using the venturi effect, and devices that include conformable balloons. Methods of treating various diseases using such devices are also disclosed, including methods of treating cerebral and spinal cavernous malformations, cavernomas, and hemangiomas, methods of treating neurological diseases, methods of treatment using multiple microfluidic delivery devices, methods of treating hearing disorders, methods of spinal drug delivery using microfluidic devices, and methods of delivering stem cells and therapeutics during fetal surgery. Methods of manufacturing such devices are also disclosed.02-07-2013
20130035661FLUID DELIVERY DEVICES AND METHODS OF USE FOR COLLAPSIBLE FLUID CONTAINERS - The present invention recognizes that there exits a need for a device and method to extrude fluid from a collapsible fluid bag in and uncomplicated manner using pressure, preferably to prevent or reduce the introduction of air into the fluid. A first aspect of the present invention is a medical device for administering fluid to a subject from a flexible fluid container. A second aspect of the present invention is a method of administering a fluid to a subject using a device of the present invention.02-07-2013
20130035659INFUSION PUMP WITH INDEPENDENTLY CONTROLLABLE VALVES AND LOW POWER OPERATION AND METHODS THEREOF - An infusion pump, including: a specially programmed microprocessor; a drip chamber for connection to a source of fluid and to an output tubing; a pumping section including a plurality of fingers and a first actuator, controllable using the microprocessor, for sequentially displacing the plurality of finger to compress a first portion of the output tubing to displace fluid from the drip chamber through the output tubing; an inlet valve disposed between the drip chamber and the pumping section and arranged to compress the output tubing to restrict or block flow through the output tubing; and a second actuator, controllable using the microprocessor, for opening or closing the inlet valve independent of the displacement of the plurality of fingers; or for operating the inlet valve to control a rate of flow of fluid from the drip chamber to the portion of the output tubing.02-07-2013
20130041342INSULIN PUMP AND METHODS FOR OPERATING THE INSULIN PUMP - A device and method for delivering insulin to a patient is disclosed. The method includes receiving an amount of insulin to deliver to a patient and beginning delivery of the insulin to the patient. The method further includes monitoring the delivery of the insulin to determine whether the insulin pump is able to deliver the entire amount of insulin and maintaining a timer until the insulin pump recommences the delivery of the insulin. The method includes comparing an amount of time indicated by the timer to a threshold. The method further includes generating a first insulin delivery record indicating that a first amount of insulin was delivered when the amount of time indicated by the timer is less than the threshold and a second insulin record indicating that a second amount of insulin was delivered when the amount of time indicated by the timer is greater than the threshold.02-14-2013
20120265165Tissue Expander - This invention relates to a tissue expander for use in medical, veterinary and dental applications. The tissue expander comprises a self-inflating polymer network and a biodegradable polymer having a non-degraded state and a degraded state which in the non-degraded state constrains the inflation of the self-inflating polymer network and in the degraded state allows inflation of the self-inflating polymer network. In a preferred embodiment, the self-inflating polymer network and the biodegradable polymer form an interpenetrating polymer network or a semi-interpenetrating polymer network. Alternatively or in addition, the self-inflating polymer network forms a core and the biodegradable polymer forms coating which partially or fully surrounds the core.10-18-2012
20100042067EMBOLIZATION PARTICLES AND METHOD FOR MAKING SAME - In at least one embodiment of the present invention, a method for making embolization particles for occluding fluid flow through a body vessel is provided. The method comprises positioning an elongated body of biocompatible material relative to a cutting device. The elongated body is defined by extrusion of a body cross-section along a longitudinal axis. The elongated body is cut with a cutting device at a plurality of locations along the longitudinal axis to form the embolization particles such that each of the embolization particles has a particle cross-section that corresponds to the body cross-section.02-18-2010
20110196335DEVICES AND METHODS FOR AGENT-ASSISTED MEDICAL PROCEDURES - Various embodiments of bulking or cushioning agents or material and related medical devices and methods are disclosed. For example, a method of performing a medical procedure in a tract of a body may include injecting a material in a liquid phase proximate a target site between a first tissue layer and a second tissue layer, allowing the material to transition from the liquid phase to the gel phase in response to a raise in temperature of the material to approximately at or above the predetermined temperature, and performing a surgical procedure on the target site. The material may have the liquid phase at temperatures below a predetermined temperature and a gel phase at temperatures approximately at or above the predetermined temperature.08-11-2011
20100106130METHOD FOR TREATING OBESITY BY EXTRACTING FOOD - The present invention is directed to an apparatus and method for treating obesity. An artificial obstruction is introduced into the patient's gastrointestinal tract, and a tube is positioned that passes through a patient's abdominal wall into the upper digestive system of the patient. The patient is allowed to carry out his/her everyday affairs including ingesting food. After the patient has ingested food, the food is extracted by pumping it out of the upper digestive system through the tube. The present invention is less invasive than current surgical procedures for reducing weight and allows patients to live a normal and active lifestyle without experiencing adverse side effects.04-29-2010
20100106131METHOD FOR TREATING OBESITY BY EXTRACTING FOOD - The present invention is directed to an apparatus and method for treating obesity. A tube is positioned that passes through a patient's abdominal wall into the upper digestive system of the patient. The patient is allowed to carry out his/her everyday affairs including ingesting food. After the patient has ingested food, the food is extracted by pumping it out of the upper digestive system through the tube. The present invention is less invasive than current surgical procedures for reducing weight and allows patients to live a normal and active lifestyle without experiencing adverse side effects.04-29-2010
20090149829Ophthalmic fluid delivery system - A method of safely delivering an ophthalmic fluid to an eye, the method including targeting the eye with an ophthalmic fluid misting device and activating an ultrasonic generator to deliver the ophthalmic fluid from the ophthalmic fluid misting device across a space between the misting device and the eye. The method further including maintaining a momentum of the ophthalmic fluid that is insufficient to trigger at least one of the ocular blink reflex and the lacrimation reflex of the eye.06-11-2009
20090124994MINIATURE DRUG DELIVERY PUMP WITH A PIEZOELECTRIC DRIVE SYSTEM - A drug delivery pump which uses a piezoelectric drive system to advance a small syringe piston to deliver a liquid drug and a method thereof are disclosed. The present invention has a cost and size advantage compared to traditional pumps and is a very compact and potentially disposable pump device design.05-14-2009
20130046278Internal Dry Powder Delivery System and Method Thereof - An internal dry powder delivery system through a working channel of an endoscopic cannula for directly applying the powder form medication to an internal tissue/organ site, includes an elongated tubular delivery channel and a powder supply device for producing pressurized gas mixing with the dry powder for feeding to form a mixture of dry powder and pressurized gas delivering to an internal tissue/organ site through the delivery channel via endoscopic cannula. It ensures a smooth powder release by preventing liquid from accumulation at the tip of the delivery channel and offers physicians a new powder form drug delivery method via endoscope. Also, it offers new minimal invasive application by directly and precisely applying the powder format drug to the internal sites of human gastrointestinal organ via endoscope to achieve hemostasis, anti-inflammation, anti-ulcer and anti-tumor treatment, etc.02-21-2013
20130046277DEVICE AND METHOD FOR THE AUTOMATIC INITIATION OF AN INJECTION - A system and method to automatically initiate an injection procedure of a medicament into a patient. In the system, a delivery assembly includes an injector for infusing the medicament into the patient. Further, the system includes a monitor for detecting a parameter characteristic of the procedure, for instance, a pressure indicative of a partial vacuum between the injector and the injection site, a pressure exerted by the patient against the delivery assembly, a conductance, a capacitance, or an optical blood reading. Also, the system includes a timer for determining compliance of the parameter within a predetermined range during a first time interval. In response to the timer, an actuator initiates the injection procedure at the expiration of the first time interval. Further, the actuator may stop the injection procedure if the parameter is outside the predetermined range during a second time interval.02-21-2013
20130046276Dispensing Fluid from an Infusion Pump System - Some embodiments of an infusion pump device may include a drive system that accurately and incrementally dispenses fluid from the pump device in a controlled manner. Particular embodiments of the drive system may include a rotational motor that is coupled to a string member, which is used to adjust a pawl relative to a ratchet body. In such circumstances, the drive system can provide a reliable and compact infusion pump device that accurately dispenses the desired volume of fluid.02-21-2013
20130046275MATERIAL AND METHOD FOR TREATING INTERNAL CAVITIES - A hydrophilic biocompatible sustained-release material is disclosed. The material comprises amounts of Pluronic F-127, PEG-400, HPMC and water, effective to produce a composition of sufficiently low viscosity at room temperature to be injectable into an internal body cavity via a tube inserted within a urinary catheter. At body temperature, the material exhibits a much higher viscosity and will stably adhere to the internal surface of a body cavity. As the material dissolves, a therapeutic agent incorporated therein is slowly released to the body cavity, while the material itself is excreted from the body.02-21-2013
20130046274METHOD OF CONTROLLED DELIVERY USING SUB-MICRON-SCALE MACHINES - A method for controlled delivery of a substance into a body includes administering a plurality of containment vessels into the body, in which each of the plurality of containment vessels includes a quantity of the substance loaded therein prior to the administering; and providing a time-varying magnetic field such that the plurality of containment vessels are exposed thereto to cause a release of at least a portion of the substance from the plurality of containment vessels. Each of the plurality of containment vessels has an average outer diameter less than about 1 μm.02-21-2013
20110004188DRUG DELIVERY SYSTEM WITH WIRELESS MONITOR - A portable drug delivery system (01-06-2011
20090312743Perivascular Leak Repair System - The perivascular leak repair system, and method of using the same, of the present invention provides a sealant reservoir 12-17-2009
20130090624RECAPTURE SHEATH - In some embodiments, a recapturing sheath comprises an elongate shaft having a proximal end and a distal end. The shaft defines a lumen therein. The distal end comprises a flare and a slit. A first portion of said flare overlaps a second portion of said flare.04-11-2013
20090105685Two Stage Jet Injection Device - A jet injection device comprises a medical jet unit (04-23-2009
20090093786METHOD FOR DETECTING THE OCCLUSION OF A TUBING FOR A DEVICE FOR ADMINISTERING PHYSIOLOGICAL LIQUIDS - The invention relates to a self-parameterizable method for detecting occlusion and pulling out of a tubing for ad-ministering, by enteral route, physiological liquids and to a device for carrying out said method. The inventive device comprises, in essence: a pump (04-09-2009
20130072897METHOD AND SYSTEM FOR DETERMINING INFORMATION RELATED TO A DRUG RESERVOIR - A method and system for detecting information related to a drug reservoir. The method includes transmitting energy at a coded material disposed on a drug reservoir, where the energy has at least one predefined characteristic. The coded material identifies information related to the drug reservoir. The coded material modifies the energy and emits the modified energy to a receiver. The method further includes receiving at the receiver the modified energy. The method further includes determining information related to the drug reservoir based on the modified energy as the drug reservoir is loaded into a drug delivery device.03-21-2013
20130072898METHOD AND SYSTEM FOR SUSTAINED-RELEASE OF SCLEROSING AGENT - Methods and systems for treating pleural disease comprising a providing a low dosage of a sclerosing agent over a period of time. Certain examples include catheter with a sclerosing agent that is inserted into the pleural space. The sclerosing agent is released in a sustained-release manner over a period of time to achieve diffuse pleurodesis of the pleural layers.03-21-2013
20130072896MODULAR SPACER DEVICE FOR THE TREATMENT OF INFECTIONS OF PROSTHESIS OF HUMAN LIMBS - A spacer device for the two-stage treatment of infections of the prosthesis of the human limbs, made of biologically compatible material adapted to be added and/or which can be added with pharmaceutical products, active and/or therapeutic ingredients, includes a first portion adapted to be fixed to a corresponding bone bed, and a second portion adapted to be inserted in a corresponding articular area of the patient, said first portion and said second portion being connected through adjustable joining means. The device includes mutual coupling surfaces respectively provided in said first portion and said second portion coated with said biologically compatible material. A method for locking the first portion to the second portion is also provided.03-21-2013
20110015611Aspiration prevention mechanism - A patient angle sensor is employed in conjunction with gastric feeding devices to shut off or to reverse the flow of fluid in the tube when the angle of a bed ridden patient becomes sufficient to allow gastric juices to percolate up through the esophagus and into the patient's lungs. In this way incidents of aspirational pneumonia in hospitalized patients is significantly reduced or eliminated.01-20-2011
20110015610MEDICAL FLUID CASSETTES AND RELATED SYSTEMS AND METHODS - A medical fluid delivery cassette configured for use with a medical fluid pumping system and related systems and methods. The medical fluid delivery cassette includes a base and a membrane that together define a fluid pump chamber. The medical fluid delivery cassette further includes a member configured to apply an outward force to an inner surface of the membrane.01-20-2011
20130060226TUBING SET HAVING A GATE FOR THE CONNECTION OF VIALS - The present invention refers to a tubing set suitable for use in co-operation with a medical liquid delivery device. The tubing set comprises: a delivery tube suitable for supplying a medical liquid or blood to a patient; and a vial gate for the connection of vials containing drugs to be delivered into the medical liquid or blood. The vial gate comprises a delivery lumen, suitable for delivering the drug from the vial to the delivery tube; and a vent lumen, suitable for providing a replacement fluid from a location inside the tubing set to the inside of the vial in order to replace the delivered drug. The vial gate according to the invention further comprises at least one one-way valve placed along said vent lumen or said delivery lumen.03-07-2013
20130060224Fluid Intake and Content Management System - A system for managing the fluid intake of a person is disclosed. The system consists of multiple containers of various volumes, a common lid configured to incorporate a flow control valve, multiple flow control valves having varying flow rates, a date indicator ring incorporated circumferentially on said containers, a content indicator disposed on said lid, a chiller insert, and an optional slip on handle. The user selects a container based on the fluid needs of a person and a flow control valve based on the drinking ability of the person. The user fills the container with a drinkable fluid, and indicates the nature of the contents with the content indicator and the date of filling with the date indicator ring. The chiller insert allows the user to cool the contents without the possibility of dilution as with standard ice cubes.03-07-2013
20130060225PORTABLE INFUSION PUMP AND MEDIA PLAYER - Some embodiments of a portable infusion pump system can be configured to deliver medicine (e.g., insulin or the like) to a user and to deliver media content to a user. The media content can include, for example, MP3 music and other audio/video data stored in a memory device in the portable system. Thus, in particular embodiments, the portable infusion pump system can serve a dual purpose of providing medication and entertainment for the user from a compact and unobtrusive device.03-07-2013
20120310205Medical Pump Providing Customizable Programming Permissions - A method and apparatus for delivering intravenous drugs to a patient provides for remote loading and programming of IV pumps that may be shipped in a loaded and programmed configuration to a remote site for use with the patient. A special carrier may be provided for pneumatic delivery of the preloaded pump. Password enabled customizing of pump features according to specific user's need may be provided to prevent undesired changing of the pump parameters at the remote site.12-06-2012
20090270834DRUG DELIVERY DEVICE - The invention refers to an electrically actuated, needle-free injection device. The main field of application is drug delivery. The device is based on a piezoelectric actuator (10-29-2009
20090270833Software Features for Medical Infusion Pump - Various software features useable in a medical infusion pump are disclosed. In certain aspects, localized alarm and message handling systems are disclosed. In other aspects, variable intensity alarms are disclosed. In further aspects, cost tracking systems and methods for medical infusion pumps are disclosed. In still further aspects, methods and systems implementing a variable delay of pressure decay in a medical infusion pump are disclosed. In other aspects, methods and systems implementing a timed intermittent bolus by pressure are disclosed.10-29-2009
20120226259Devices, Systems and Methods for Adjusting Fluid Delivery Parameters - Devices, systems and methods for adjusting fluid delivery based on past or historical fluid delivery data and/or personal parameters of a user are disclosed. Devices, and corresponding systems and methods, may comprise a dispensing unit configured to deliver a fluid from a reservoir into the body of a user and a processor having instructions operating thereon to retrieve data relating to one or more time windows from a memory, assess a correction delivery for the one or more time windows based on the data, determine a new CIR value for the one or more time windows if the correction delivery regularly follows a meal bolus and/or determine a new basal delivery profile for the one or more time windows if the correction delivery regularly precedes a meal bolus.09-06-2012
20120226257Deep Vein Thrombosis Therapeutic Methods Using Therapeutic Delivery Devices and Systems - Methods and devices are disclosed that, in various embodiments and permutations and combinations of inventions, diagnose and treat Deep Vein Thrombosis or associated symptoms. In one series of embodiments, the invention consists of methods and devices for identifying patients whose Deep Vein Thrombosis or associated symptoms are caused or exacerbated, at least in part, by blockages of one or more of the patient's internal peripheral veins. In some instances, stenoses or other flow limiting structures or lesions in the patient's affected veins are identified. Further, in some instances the nature of such lesions and whether there is a significant disruption of blood pressure, or both, is ascertained. In some embodiments, methods and devices for applying one or more therapies to the blockages in the patient's peripheral veins are provided.09-06-2012
20130165899DOSING UNIT, AMBULATORY INFUSION DEVICE COMPRISING DOSING UNIT AND METHOD FOR OPERATING A DOSING UNIT - A dosing unit for an ambulatory infusion device and a method of operation are disclosed. The dosing unit includes a stationary member, a movable member, and a plunger. The movable member and the stationary member, together, make a charging valve and a discharging valve. The plunger is located, at least in part, in a metering cavity of the movable member and the movable member is adapted to selectively couple and decouple a driving unit, such that, by operating the driving unit with the movable member being coupled with the driving unit, the movable member moves with the plunger to maintain a position of the plunger relative to the movable member along a displacement axis, and by operating the driving unit with the movable member being decoupled from the driving unit, the plunger is displaced while the position of the movable member is maintained.06-27-2013
20130066295POLYMERIC IMPLANT DELIVERY SYSTEM - Delivery systems for a polymeric tubular implant, kits that include such delivery systems, and methods of treating patients by implanting tubular implants using the delivery systems. The delivery systems include an inner shaft, an expandable member slidably disposed about the inner shaft and configured to receive the tubular implant, and a tubular outer shaft disposed about the inner shaft.03-14-2013
20110022025Medical device having capacitive coupling communication and energy harvesting - Provided is a wearable, self-contained drug infusion or medical device capable of communicating with a host controller or other external devices via a personal area network (PAN). The medical device utilizes a PAN transceiver for communication with other devices in contact with a user's body, such as a physiological sensor or host controller, by propagating a current across the user's body via capacitive coupling. The wearable nature of the medical device and the low power requirements of the PAN communication system enable the medical device to utilize alternative energy harvesting techniques for powering the device. The medical device preferably utilizes thermal, kinetic and other energy harvesting techniques for capturing energy from the user and the environment during normal use of the medical device. A system power distribution unit is provided for managing the harvested energy and selectively supplying power to the medical device during system operation.01-27-2011
20120116346HYPERTHERMIA INDUCED DEPOSITION OF ELASTIN FIBERS - Methods for inducing the deposition of elastin at a tissue site by exposing the tissue to hyperthermia is described herein.05-10-2012
20100087795SELF-LEARNING DRUG DELIVERY SYSTEM - Self-learning process for automatically adjusting a dosage of a substance administered to a person by a drug delivery device, a drug delivery device, wherein a dosage of a substance is adjusted by such a self-learning process and a drug delivery system comprising such a drug delivery device. Pain is experienced differently at certain times of day due to the origin causing the symptoms. Therefore, the medication providing pain relief should also be adjusted accordingly. The invention is to anticipate the pain experience and to deliver pain relief medication in such a way that Quality of Life is improved by appropriate timing of the right amount of medication and by appropriate timing of turning off the medication to reduce side effects.04-08-2010
20120238997SYSTEM AND METHOD FOR CONTROLLING ADMINISTRATION OF MEDICAL FLUID - A system for controlling administration of medical fluid includes a fluid passageway to which is attached a first flow regulator, a second flow regulator, and a flow detector. The system also includes a controller for controlling the first and second flow regulators in response to a measurement taken by the flow detector of fluid movement in the fluid passageway. The first flow regulator, such as a pump, is configured to maintain fluid movement at flow values greater than an unrestricted flow value. The second flow regulator, such as a variable adjustable valve, is configured to maintain fluid movement at a flow value less than the unrestricted flow value. A method of controlling administration of medical fluid includes obtaining a target flow value, moving fluid through the disposable assembly, taking a measurement of fluid movement in the disposable assembly, and actuating a flow regulating apparatus.09-20-2012
20120238995Medicament Dispensing Devices and Methods - A medicament dispensing device including a substantially rigid carpule body which has a dispensing end and an actuation end opposite the dispensing end. The carpule body is substantially tubular and thus defines a carpule bore. The device further includes a plunger operatively disposed within the carpule bore having a plunger actuator near the actuation end of the carpule body and a plunger tip opposite the plunger actuator. The plunger tip and an orifice at the dispensing end of the carpule bore define a medicament volume which may be loaded with a medicament selected to achieve specific therapeutic goals. The carpule body may also include a wound depth scale. The depth scale is typically associated with the dispensing end of the carpule body. Similarly, the medicament dispensing device may include a dosage scale. Also disclosed are methods of dispensing medicaments.09-20-2012
20080294141MULTIPLE ROBOTIC INJECTIONS OF IMMUNOSUPPRESSIVE DRUGS BASED ON SCANNED IMAGE - A system for delivering an immunosuppressive drug to a transplanted organ within a body may include an injection system having an injector configured to inject an immunosuppressive drug into the transplanted organ, and a robotic system configured to position the injector at one or more injection locations within the body. A method of delivering an immunosuppressive drug to a transplanted organ within a body may include injecting the immunosuppressive drug into one or more locations within the transplanted organ so as to suppress white cell infiltration into the transplanted organ without affecting white cell activity at locations outside of the transplanted organ.11-27-2008
20110028937AUTOMATED FLUID FLOW CONTROL SYSTEM - A system for controlled delivery of medicinal fluid includes a fluid pathway assembly defining a fluid pathway and including means for calculating a first calculated fluid flow rate using gas laws. The fluid pathway assembly has an inline flow sensor element received within the fluid pathway movable in response to fluid flowing in the fluid pathway. A flow control device is removably attached to the fluid pathway assembly and has a sensor for sensing a position of the inline flow sensor element in the fluid pathway, the position of the inline flow sensor element being representative of a second calculated fluid flow rate. The fluid pathway assembly includes a variable flow resistor adjustable to regulate a rate of fluid flow in the fluid pathway assembly. A drive mechanism attached to the flow control device is operably coupled to the variable flow resistor when the flow control device is attached to the fluid pathway assembly. The variable flow resistor is adjustable by the drive mechanism to achieve a target flow rate when the first calculated flow rate and/or the second calculated flow rate differs from the target flow rate.02-03-2011
20120271273MEDICAL FLUID AUTOCONNECTION AND AUTOIDENTIFICATION METHOD - A medical fluid autoconnection method includes: enabling acceptance a pierceable connector that is capable of fluidly communicating with a source of medical fluid into a moveable holder; temporarily fixing a spike to a medical fluid pumping machine; automatically detecting whether the pierceable connector has been placed into the moveable holder; if the pierceable connector is sensed as being placed in the moveable holder, moving the holder so that the spike pierces the pierceable connector; and enabling medical fluid to be pumped from the source through the connected spiked and connector.10-25-2012
20100094247BIFURCATED BALLOON & STENT DELIVERY SYSTEM - A bifurcated balloon for in vivo use, comprises: a proximal hollow tubular element, two bifurcating hollow tubular elements extending distally from a distal end of the proximal hollow tubular element, each of the two elements comprising: a first distal tubular element guidable into a first branch of a vessel bifurcation, and a second distal tubular element guidable into a second branch of the vessel bifurcation. The bifurcated balloon further comprises a longitudinal chamber extending from a distal end of the first distal tubular element, and a first substantially longitudinal guidewire channel passing through the longitudinal chamber, the first guidewire channel having two ends of which a first end passes through a proximal portion of the longitudinal chamber.04-15-2010
20090306621Vial transfer convenience IV kits and methods - Convenience kits designed to provide for closed, but selectable liquid transfer from a vial to a variety of IV containers and medical syringes. In particular, a kit for fully enclosing a vial for safety in hazardous drug transfer is disclosed. Generally, the kits contain unitized parts wherever reasonable to limit makes and breaks. Further, pathway determining kits provide selectable pathways for purging connections wish flushing solution where makes and breaks are made between various fluid pathway involved parts such that, when disconnections are made, flush solution is resident at the exposed interface. Also disclosed is a 3-way valve as part of a closed, switchable pathway controlling subsystem by which pathways are selected for reconstituting dry medicine in a vial, displacing a measured dose of liquid from a vial, exchanging gas into the vial for displaced liquid, delivering the measured dose to an IV container.12-10-2009
20120065616Ultrathin Multilayered Films for Controlled Release of Anionic Reagents - Multilayered films, particularly ultrathin multilayered films comprising cationic polymers which are useful for controlled release of anionic species, particularly for controlled release of nucleic acids. The multilayer films herein are useful for temporal controlled released of anionic species, particularly one or more anionic peptides, proteins, nucleic acids or other anionic biological agents. In one aspect, the invention relates to multilayer films which release anionic species (anions) with separate and/or distinct release profiles, particularly wherein the anions are one or more anionic peptides, proteins or nucleic acids or other anionic biological agents.03-15-2012
20100152699Nanochanneled Device and Related Methods - A nanochannel delivery device and method of manufacturing and use. The nanochannel delivery device comprises an inlet, an outlet, and a nanochannel. The nanochannel may be oriented parallel to the primary plane of the nanochannel delivery device. The inlet and outlet may be in direct fluid communication with the nanochannel.06-17-2010
20100249746DRUG DELIVERY SYSTEM FOR ACCELERATED SUBCUTANEOUS ABSORPTION - A method for accelerating subcutaneous absorption of a fluid or drug into the systemic circulation of a specific targeted tissue. A first drug operative to produce local capillary vasodilatation and/or increase the rate of bulk flow of solution through the interstitial space is mixed with a fluid. The fluid may contain a crystalloid solution or a dilute solution of a pharmacologic drug required for a routine or emergency therapeutic treatment for a patient. The first drug is substantially non-toxic to the patient. The fluid mixed with the first drug is then delivered subcutaneously or into deeper tissues of the patient, by use of a hyperdermic needle or infiltration cannula. As the capillaries are dilated, the fluid is efficiently absorbed and circulated systemically.09-30-2010
20100268188DRUG DELIVERY CUFF - Embodiments provide a drug delivery cuff including a drug reservoir. In an embodiment, an integrated drug pump may be provided. A drug delivery cuff in accordance with an embodiment may be placed around any suitable vascular graft (e.g., ePTFE) or directly around any natural tissue conduit (e.g., perivascularly), at any position along the graft/conduit or overlapping a graft and conduit, either at the time of graft surgical placement or separate therefrom.10-21-2010
20090306622Devices, systems, and methods for reshaping a heat valve annulus - Devices, systems, and methods employ an implant that is sized and configured to attach to the annulus of a dysfunctional heart valve annulus. In use, the implant extends across the major axis of the annulus above and/or along the valve annulus. The implant reshapes the major axis dimension and/or other surrounding anatomic structures. The implant restores to the heart valve annulus and leaflets a more functional anatomic shape and tension. The more functional anatomic shape and tension are conducive to coaptation of the leaflets during systole, which, in turn, reduces regurgitation. The implant improves function to the valve, without surgically cinching, resecting, and/or fixing in position large portions of a dilated annulus, or without the surgical fixation of ring-like structures.12-10-2009
20110301565MEDICAL BALLOONS HAVING A SHEATH DESIGNED TO FACILITATE RELEASE OF THERAPEUTIC AGENT - Medical devices that comprise an elongate balloon and a sheath positioned around the balloon. The sheath is designed to facilitate the delivery of therapeutic agent. In one embodiment, the sheath has a non-circular shape (e.g., a square shape or polygonal shape). In some cases, the sheath has reservoirs at the corners with a therapeutic agent contained in the reservoirs. In another embodiment, the sheath has an area that undergoes shear strain when the balloon is expanded. The shear strain in the sheath facilitates the release of therapeutic agent. In another embodiment, the sheath has a chamber for containing a therapeutic agent. When the balloon expands, the chamber becomes compressed and causes the therapeutic agent to flow out of the chamber.12-08-2011
20110301567Pump Set with Secure Loading Features and Related Methods Therefor - A pump set for use in a liquid delivery pump of the type for delivering liquid to a patient, having an infrared radiation detector for detecting infrared radiation, and providing an indication that the pump set is properly loaded on the pump. The pump set comprises a conduit for the liquid and a safety interlock member which is carried by the conduit. The safety interlock member is formed of a material that transmits infrared radiation and blocks visible light12-08-2011
20110301566Cartridge connection method for precise delivery of liquid - A mobile medical pump has a tubular cartridge unit with a first end having an interface to an infusion line and a second, open end having a first engagement interface, with a piston inserted in the cartridge and engaging an inner diameter of the cartridge, such that translation of the piston within the cartridge will draw in or expel liquid to or from the cartridge, a case housing having an opening for inserting the cartridge and an internal second engagement interface at a depth that, with a cartridge fully inserted and the first and second engagement interfaces joined, an infusion line may be connected to the first end external to the case, and a piston rod within the case housing, the piston rod having a permanent magnet at a first end with a planar surface orthogonal to a longitudinal axis of the piston rod, and a threaded opening at an opposite end engaging a rotatable translation screw driven by a translation drive system including an electric motor. With the piston rod set at a preprogrammed position, inserting a charged cartridge into the case to engage the first and second engagement interfaces, causes the magnet end of the piston rod to securely contact a steel plate embedded in the piston, such that translation of the piston rod by the translation drive system will expel liquid from the cartridge, and holding the piston rod motionless will hold the piston motionless, preventing any discharge of liquid from the cartridge.12-08-2011
20120109101SYSTEM FOR ACCESS INTO BODILY CAVITY - An assembly and method for percutaneous placement of a catheter comprising an elongated hollow catheter having a distal end and a reduced cross-section portion at a proximal end thereof. An introducer needle is slidably mounted over said catheter. The introducer needle has an elongated slit adapted to slide over the reduced cross-section portion to separate the needle from the catheter. A syringe may be attached to the proximal end of the catheter. Also, a valve may be attached to the catheter to permit easy collection of fluid.05-03-2012
20120109098Applicator Tips Having Mixing Ball - Applicator tips in accordance with the present disclosure include a body portion and dispensing tip. The body portion includes a proximal end having an inlet adapted for fluid communication with a fluid source, a distal end including an opening, and a mixing chamber disposed therebetween. The mixing chamber includes at least one mixing ball and at least one biologically active agent disposed therein. The dispensing tip defines a lumen therethrough. The lumen is in fluid communication with the opening of the distal end of the body portion and includes an outlet for passage of a fluid therethrough.05-03-2012
20110288521INTRADERMAL INJECTOR AND USES THEREOF - The invention provides for a needle-free or needle-less intradermal injection device that is capable of delivering an agent of interest to only the intradermal space. The intradermal device can deliver lower volumes of an agent than commonly used with present devices. In one aspect of the invention, the intradermal device is useful for delivering one or more agents to the intradermal space for eliciting immune responses particular to the dermal layer. In other aspects of the invention, the intradermal device is useful for delivering one or more agents to the intradermal space for treating, delaying development of delaying the progression of preventing, and/or ameliorating symptoms of various diseases, disease states, and conditions.11-24-2011
20110288523Digital Syringe With Compensation Control - A syringe for performing a medical procedure includes a pressure sensor, a volume sensor, and a compensation circuit. The volume sensor measures a volume of a flowable material that is dispensed from the syringe, the pressure sensor measures a pressure being applied to the flowable material, and the compensation circuit calculates a delivered volume of the flowable material by accounting for system compliance (expansion) as the pressure is increased. By compensating for system compliance in this manner, a syringe can be used in high pressure procedures while still providing accurately controllable material delivery.11-24-2011
20110288522APPARATUS AND METHODS FOR DETACHING AN EXPANDABLE MEMBER FROM A MEDICAL DEVICE - A medical implant device includes a shaft, an expandable member coupled to the distal end portion of the shaft, a sleeve and a detachment mechanism. The expandable member is configured to move between a collapsed configuration and an expanded configuration, and can be used to deliver a medicament, a therapeutic substance and/or a structural member into the body. The sleeve is coupled to the distal end portion of the shaft, and is configured to move relative to the shaft between a first position and a second position. The sleeve is configured to be disposed about the expandable member when in the first position and disposed apart from the expandable member when in the second position. The detachment mechanism is coupled to the distal end portion of the shaft, and is configured to detach the expandable member from the shaft when the sleeve is in the second position.11-24-2011
20090157038Poultry vaccination apparatus and method - An apparatus for providing multiple vaccinations of poultry simultaneously is described. A neck injection, breast injection, two wing injections, and an eye mist or drop may be performed in one operation. The apparatus holds the bird in position for precise location of injections, thereby reducing wasted vaccine. The risk of injury to the bird during the process is minimized by greatly reducing the manual handling of the bird during vaccination. Vaccination costs are also reduced by the reduction of labor otherwise required in this process.06-18-2009
20090312741BIORESORBABLE COMPOSITION AND A MEDICAL DEVICE COMPRISING SAID COMPOSITION - The invention provides a bioresorbable composition comprising a mixture of at least one polymer and capsules, which capsules comprise an inner part which is encapsulated by a shell which shell is at least partly decomposable by application of an external stimulation source. The invention also relates to a medical device comprising said composition.12-17-2009
20110295227SHOCKWAVE VALVULOPLASTY CATHETER SYSTEM - A valvuloplasty system comprises a balloon adapted to be placed adjacent leaflets of a valve. The balloon is inflatable with a liquid. The system further includes a shock wave generator within the balloon that produces shock waves. The shock waves propagate through the liquid and impinge upon the valve to decalcify and open the valve.12-01-2011
20100069878Intracavitary Radiation System - A system is provided for use in brachytherapy where a central tube permits passage of a radioactive source therethrough to deliver a prescribed dosage of radiation. One or more balloons are coaxially positioned around the central tube. At least one balloon includes one or more peripheral tubes extending along at least a portion of the balloon. The peripheral tube is also attached to the high dose rate brachytherapy unit in order to permit passage of a radioactive source therethrough.03-18-2010
20120191060LOW PROFILE ACTUATOR AND IMPROVED METHOD OF CAREGIVER CONTROLLED ADMINISTRATION OF THERAPEUTICS - A polymer actuator, power supply and method of using the activation are described.07-26-2012
20120191059CASSETTES AND METHODS OF USING SAME - The present disclosure provides cassettes and methods of using same for the delivery of fluids to a patient using fluid delivery systems. In a general embodiment, the cassettes of the present disclosure include a flexible tube, a housing having a recessed area and first and second ends for holding the flexible tube, and at least two additional components including, for example, different sensors, false reading components for sensors, anti-flow valve means, insertion guides, directional indicators, latch mechanisms, kink-prevention notches, etc. Such additional components provide the cassettes of the present disclosure with several advantages including, for example, quality control, efficiency of use, cost effectiveness, and safety of use.07-26-2012
20100036361SYSTEM AND METHOD FOR DELIVERING MULTIPLE IMPLANTS INTO LUNG PASSAGEWAYS - A system for delivering multiple implants into lung passageways is disclosed. The system comprises a catheter configured to receive and store a plurality of expandable implants, and an actuatable delivery tool coupled to the proximal end of the catheter. The system expels an implant of the plurality of implants with each actuation of the delivery tool. The delivery tool comprises a plunger element which extends through the catheter from the proximal to the distal end and allows the delivery tool to mechanically communicate with the implants. In one embodiment, the system comprises a spring-loaded slidable element, and a user compresses the slidable element to actuate the delivery tool. In another embodiment, the system comprises a rotation rod, and the user moves the rotation rod in a distal direction to actuate the delivery tool.02-11-2010
20110202032DRUG-DELIVERY PUMPS WITH DYNAMIC, ADAPTIVE CONTROL - In various embodiments, actuation of a drug-delivery pump is controlled based on a change in a condition of the pump.08-18-2011
20100204675CATHETER ASSEMBLY AND COMPONENTS THEREOF - Catheter assemblies are generally discussed herein with particular discussions extended to catheter assemblies having a tip protector, a valve, a valve opener, and optionally a needle wiper. The valve opener is disposed inside a catheter hub and is configured to be pushed by an IV set luer connector to open a valve following successful catheterization to pass fluids or other solutions through the catheter. A tip protector is incorporated to block the needle tip and prevent the same from accidental needle stick. A wiper is optionally included to wipe blood deposits on the needle when the same is retracted from the catheter.08-12-2010
20110196336VISCOUS FORMULATIONS AND THEIR USE IN NEEDLE-FREE INJECTION - Formulations are described that are viscous and will benefit from needle-free delivery at high driving pressures. Conventional delivery of these viscous formulations by hypodermic syringes is inconvenient as well as painful. Formulations include those which have a viscosity of about 5 cS or more at about 20° C. and which can have 0.5 ml or more administered by a needle-free injector in about 0.1 second±0.02 seconds.08-11-2011
20120065615NEEDLE-FREE INJECTORS AND DESIGN PARAMETERS THEREOF THAT OPTIMIZE INJECTION PERFORMANCE - A needle free injector system and a method for delivering a formulation using this system are disclosed. The method comprises actuating a needle free injector to pressurize a liquid formulation and force the formulation through an orifice in a skin puncture phase followed by injection of the formulation during a delivery phase. The skin puncture phase is defined by a pressure profile vs. time curve after actuation which has a main pressure peak with a maximum pressure. The delivery phase occurs at a lower pressure than the maximum pressure of the main peak pressure. The device may have one or more orifices and pressurizing the formulation during the puncture phase and delivery phase to extrude the formulation through each orifice is structured so as to improve characteristics of needle free delivery.03-15-2012
20100121306COLLAPSIBLE RESERVOIR FOR USE WITH A DELIVERY DEVICE - Disclosed is a therapeutic fluid reservoir to be used with an ambulatory portable infusion device. The reservoir includes a pliable shell defining a varying inner volume that varies based on the volume of therapeutic fluid held inside the reservoir, the varying inner volume having a predetermined maximum volume for containing a corresponding volume of therapeutic fluid and an outlet port for communicating fluid from the reservoir to a patient, the varying inner volume decreasing upon therapeutic fluid being communicated through the outlet port. Upon the reservoir reaching the predetermined maximum volume when being filled with therapeutic fluid, any therapeutic fluid in excess of the predetermined maximum volume driven into the reservoir causes a substantially corresponding amount of therapeutic fluid to exit out of the reservoir via the outlet port and/or at least one other port provided in the pliable shell.05-13-2010
20120095435DELIVERY OF A SOLID BODY AND/OR A FLUID USING A LINEAR LORENTZ-FORCE ACTUATED NEEDLE-FREE JET INJECTION SYSTEM - A method for transferring a solid body across a surface of a biological body includes (i) applying an electrical input to a controllable electromagnetic actuator; (ii) producing with the electromagnetic actuator a mechanical force corresponding to the electrical input; and (iii) applying the mechanical force to a reservoir coupled at one end to a nozzle, the mechanical force producing a pressure within the reservoir, a magnitude of the pressure varying with the mechanical force and causing ejection of a fluid from the reservoir to drive the solid body into the biological body. A method for delivering a substance to a target body includes (i) positioning a needle-free injector proximate to a surface of the target body; (ii) injecting the substance into the target body; and (iii) while injecting, moving the needle-free injector along the surface, thereby sweeping the surface.04-19-2012
20110270218DRUG DELIVERY DEVICE - A drug delivery device having a housing containing a gas generator controlled by an electronic controller. The gas generator generates gas into a reciprocable chamber, whereby reciprocation of the chamber causes a lever to reciprocate a pawl, and this action causes a ratchet to The device may also be provided with manually control for delivering a bolus dose of drug when necessary.11-03-2011
20120109100Operating A Portable Medical Device - Some embodiments of a portable medical device, such as an infusion pump, can receive an external reference signal (e.g., a radio, cellular and/or satellite signal) to provide an automatic time-setting and maintenance operation. In these circumstances, the medical device can maintain accurate time and date information even in the event of a power interruption, a time-zone change and/or an internal clock error, for example. In this manner, the portable medical device provides safe operation and added convenience to the user.05-03-2012
20120109099IMPLANTABLE MEDICAL PUMP DIAGNOSTICS - A method of detecting a fault condition within an implantable medical pump comprises delivering therapeutic fluid using a medical pump comprising an actuation mechanism configured to be energized to provide a pump stroke, detecting a property associated with energizing the actuation mechanism, and determining whether the property associated with energizing the actuation mechanism indicates that a fault condition exists with the medical pump.05-03-2012
20100030185Remote controller for substance delivery system - Embodiments of a system including a remotely controlled substance delivery device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, a delivery device or related device may be placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. The concentration of a substance in the fluid to be delivered may be modified by a remote control signal. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used.02-04-2010
20110172632METHOD OF DELIVERING A BIPHOSPHONATE AND/OR STRONTIUM RANELATE BELOW THE SURFACE OF A BONE - A method for delivering a bisphosphonate and/or strontium ranelate below the surface of a bone using a mechanical force. The method includes the steps of combining a bisphosphonate and/or strontium ranelate with a carrier to form a delivery composition and delivering an effective amount of the delivery composition below the surface of the bone with a mechanical force. Also provided is a method for strengthening a portion of a bone. This method includes the step of delivering an effective amount of a bisphosphonate and/or strontium ranelate below the surface of a portion of a bone with a mechanical force.07-14-2011
20090182302Method and apparatus for pressurizing a body cavity for diagnostic and rehabilitative purposes - A method and apparatus for both the diagnostic measurement and therapeutic treatment of a body cavity. According to one form of the method of the invention, a fluid (liquid or gas) under pressure is introduced into a selected body cavity while monitoring the pressure or flow of the fluid (liquid or gas) into the cavity. Following pressurization of the body cavity, fluid (liquid or gas) inflow and outflow data is collected and analyzed. The data collected is used to draw various conclusions about the biomechanical properties of the body cavity and the organ in which it is present, and also to draw conclusions about presence or absence of disease as well as the character of disease. According to another method of the invention, a fluid (liquid or gas) is controllably infused into the body cavity to controllably expand the body cavity for purposes of therapeutic treatment.07-16-2009
20090287179Devices, systems, and methods for reshaping a heart valve annulus, including the use of magnetic tools - Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools.11-19-2009
20110270214ELECTRONICALLY ASSISTED DRUG DELIVERY DEVICE - The present invention relates to electronically assisted drug delivery devices (11-03-2011
20080208161Application of procedure through natural orifice - The application of the procedure through a natural orifice of the present invention includes the steps of: inserting a flexible endoscope through the natural orifice to the alimentary tract; incising the close-contact portion of the alimentary tract and the gall bladder under a guidance of a device for identifying the positional relationship from the alimentary tract side and forming an puncture; extracting stones in the gall bladder from the body; and removing the endoscope after completing the procedure.08-28-2008
20110270213TUBE BRACKET FOR FLUID APPARATUS - A bracket is provided. In an embodiment, the bracket comprises a first seat and a second seat. The first seat is sized to retain a first fluid implement. The second seat is sized to retain a second fluid implement from the bracket. The second seat includes a top opening, a side opening and a front concave portion. The second seat is configured to prevent inadvertent removal of the second fluid implement from the bracket. A fluid delivery apparatus including the bracket, as well as a method for delivering fluid, such as medical fluids including nutritional fluids, and industrial fluids through the delivery apparatus is also provided.11-03-2011
20090281517SYSTEM AND METHOD FOR REPAIRING AN INTERVERTEBRAL DISC - Systems for minimally invasive disc augmentation include an anulus augmentation component and, optionally, a nucleus augmentation component. Both are suited for minimally invasive deployment. The anulus augmentation component shields weakened regions of the anulus fibrosis and/or resists escape of natural nucleus pulposus and/or the nucleus augmentation component. Methods and deployment devices are also disclosed. Systems and methods for closing a defect in the anulus are also provided.11-12-2009
20120271274TUBING SET HAVING A GATE FOR THE CONNECTION OF VIALS - The present invention refers to a tubing set (10-25-2012
20090287180DISPOSABLE PUMP RESERVOIR AND RELATED METHODS - A device comprises a reusable and a disposable comprising at least one first chamber holding a flow material and a second chamber holding a gas. The disposable is removable from the reusable and maintains sterility when removed from the reusable. Flow metering device provide safety and allow for variably stroke frequency thereby modulating flow rate.11-19-2009
20090287178Interosmolar fluid removal - There are many medical situations that require removal of fluid from a patient. There are many ways to remove the fluid but many of these situations have not been solved. Herein, inventions are disclosed that generate osmotic pressure that can be used to remove these fluids very effectively, a technique which requires no harsh suction or pumping. One embodiment involves implanting a reservoir that has a semipermeable membrane sidewall. The reservoir contains trapped osmotic solutes that can not pass out through the membrane. But fluid from the patient can flow in. The osmotic pressure from the trapped solutes in the reservoir draws fluid from the patient across the semipermeable membrane and into the device. In some versions, the membrane can be changed as desired during the lifetime of the device by pulling the membrane out through the implanted device and putting a new one back in.11-19-2009
20090299327INFLATABLE MEDICAL DEVICES - Inflatable medical devices and methods for making and using the same are disclosed. The inflatable medical devices can be medical balloons. The balloons can be configured to have a through-lumen or no through-lumen and a wide variety of geometries. The device can have a high-strength, non-compliant, fiber-reinforced, multi-layered wall. The inflatable medical device can be used for angioplasty, kyphoplasty, percutaneous aortic valve replacement, or other procedures described herein.12-03-2009
20110202033COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF CARDIAC ISCHEMIC INJURY - Disclosed herein are compositions and methods for the treatment and/or prevention of pathological conditions associated with ischemia/reperfusion injury and/or hypoxic injury of myocardial cell or tissue.08-18-2011
20110270216METHOD AND APPARATUS FOR COMPENSATING FOR INJECTION MEDIA VISCOSITY IN A PRESSURIZED DRUG INJECTION SYSTEM - A needleless injection system is provided to deliver therapeutic fluids to an internal treatment site in a patient, where the system is pressurized and is capable of compensating for differences in injection media viscosity and mechanical system characteristics. In one aspect, a needleless therapeutic fluid injection system is provided that includes modular, interchangeable components. In particular, the system includes a console that generally includes the electronic and/or hydraulic control components for the system, an injection chamber, and a shaft or catheter tube.11-03-2011
20110270212PHARMACOKINETIC CONTROL FOR OPTIMIZED INTERFERON DELIVERY - Methods and devices for treating patients having chronic hepatitis C infection so as to eradicate detectable HCV-RNA and/or inhibit the emergence of a drug resistant HCV variant are disclosed. Certain methods of the invention involve the use of a continuous infusion pump in a multiphasic combination therapy using a therapeutically effective amount of a small molecule inhibitor such as ribavirin and a therapeutically effective amount of interferon-α.11-03-2011
20090275913DEVICES, APPARATUS, AND METHODS FOR BILATERAL APPROACH TO DISC AUGMENTATION - A method of augmenting a nucleus pulposus of an intervertebral disc comprises forming a first opening in an annulus of the intervertebral disc and forming a second opening in the annulus of the intervertebral disc. The method further comprises providing a space creation instrument including an expandable spacing device and introducing the spacing device through the first opening and into the nucleus pulposus. The method further comprises introducing a material delivery instrument through the second opening and into the nucleus pulposus and expanding the spacing device to create a space within the nucleus pulposus. The method also comprises injecting a biocompatible material from the material delivery instrument and into the space within the nucleus pulposus.11-05-2009
20110208153FORMULATIONS AND METHODS FOR NUTRIENT DELIVERY - The present disclosure provides formulations and methods for delivering water-soluble and lipid-soluble nutrients for preventing or correcting nutrient deficiencies to subjects requiring small-volume nutritional support, such as preterm infants. The formulations may comprise an emulsion of docosahexaenoic acid (DHA) stabilized by a protein emulsifier, such as α-lactalbumin, and may further comprise other valuable nutrients, such as arachidonic acid (ARA), arginine, glutamine, arginyl-glutamine dipeptide and/or alanyl-glutamine dipeptide. The formulation is useful, for example, for correcting nutritional deficiencies by increasing a subject's intake of nutrients such as ω-3 or ω-6 long-chain polyunsaturated acids, proteins, peptides, vitamins, minerals, other fatty acids, and/or essential amino acids. The nutritional formulation is suitable for enteral delivery and small-volume delivery via nasogastric tube, intragastric feeding, transpyloric administration and/or any other means of administration that result in the introduction of the nutritional formulation into the digestive tract of a subject.08-25-2011
20120296310INSULIN PUMP HAVING MISSED MEAL BOLUS ALARM - A pump for delivering insulin to a user. The pump comprises a pump mechanism and a meal-bolus program module. The meal-bolus program module is programmed to control the pump mechanism to deliver a meal bolus. An alarm program module is in data communication with the alarm, the timer, and the meal-bolus program module. The alarm module is programmed to generate an alarm signal when the meal-bolus program module does not control the pump mechanism to deliver a meal bolus within a predetermined period of time.11-22-2012
20110144618SHEATH INTRODUCTION APPARATUS AND METHOD - The present disclosure relates to a sheath system for enabling access through an opening in the body of a patient is provided. The sheath system includes a dilation assembly having a radially expandable tubular sheath defining a lumen having a first cross-sectional area when in a non-expanded condition, and a handle assembly operatively coupled to a proximal end of tubular sheath, the handle assembly defining an aperture formed therein, and a first thread defined on the handle in the aperture thereof. The sheath system further includes an expansion assembly including a tubular member defining a lumen having a second cross-sectional area which is larger than the first cross-sectional area of the tubular sheath of the dilation assembly and having an outer surface defining a second thread, the second thread being arranged for engaging the first thread.06-16-2011
20080287907Systems and methods for introducing and applying a bandage structure within a body lumen or hollow body organ - Systems and methods provide intraluminal delivery of a bandage structure within a body lumen or hollow body organ.11-20-2008
20130218124MYOCARDIAL DRUG DELIVERY APPARATUS AND METHOD - Embodiments provide apparatus and methods for delivering solid form drug (SFD) to various locations in the body. In one embodiment, the invention provides an apparatus for treatment of arrhythmia comprising a drug delivery member (DDM) coupled to a drug storage device (DSD). The DSD is configured to store and advance SFD (e.g., drug pellets) through the DDM to a target tissue site (TTS) in or on the heart. A drug advancement member may be used to advance the SFD through the DSD. A capture chamber (CC) may be coupled to the DDM. and is configured to be positioned on a heart surface and allow SFD to dissolve to deliver a drug solution to the heart. The DSD can be implanted subcutaneously e.g., in the pectoral area. Embodiments of the apparatus can be used to store and deliver SFD to the heart or other TTS over an extended period of years.08-22-2013
20080287906EXTRAVASCULAR SYSTEM VENTING - A vascular access device may form part of an extravascular system and function as an adapter including a gas permeable vent. A method of venting a medical device may include providing a vascular access device as part of an extravascular system, providing a gas permeable vent within the vascular access device, venting gas from the system through the vent, and closing the vent.11-20-2008
20080306465Adjustable Length Catheter - An adjustable length catheter device, a kit and a method of providing the adjustable length catheter device to a patient are provided. The catheter device includes an elongate shaft having a proximal portion, a distal portion, a first lumen and a second lumen extending at least partially therethrough. The catheter device further includes a manifold operably connected to the shaft. The manifold is configured to longitudinally move along the shaft towards the distal portion for separating the proximal portion of the shaft into a first proximal shaft portion including the first lumen and a second proximal shaft portion including the second lumen.12-11-2008
20110004190APPARATUS AND METHOD FOR PREVENTING FREE FLOW IN AN INFUSION LINE - An apparatus and method for preventing free flow through an infusion set utilizes an occluder disposed within the infusion set to selectively prevent flow therethrough. The occluder may be responsive to a pressure differential within the infusion set or may respond to compression of the infusion set. The occluder may also be configured to allow flow when the infusion set adjacent the occluder is moved sideways relative to the occluder or maintained at an angle relative to the occluder. When a pair of occluders are used in sequence, an in-line pump may be formed.01-06-2011
20090030397BARRIERS AND METHODS FOR PRESSURE MEASUREMENT CATHETERS - Methods and apparatus of the present invention provide viscoelastic barrier materials for use as barriers in devices such as pressure measurement catheters. Improved barrier materials sometimes include at least one barrier material precursor combined with an amount of a softener. In other embodiments, two barrier material precursor components are combined without a softener to provide a fully cross-linked barrier material having certain softness characteristics. In various embodiments, a softener may be dimethyl silicone oil and may be combined with a barrier material precursor in an amount of between about 25% and about 45% by weight, relative to the final barrier material. Once a viscoelastic barrier material is prepared, it may be placed in a pressure transmission catheter or similar device, for example by injecting the gel into a lumen of the catheter via a syringe. Barrier materials of the present invention have one or more advantageous properties, such as a desired softness, full cross-linking, resistance to washout from a catheter, enhanced stability and/or the like.01-29-2009
20110208154DOSING DEVICE FOR AN INFUSION SYSTEM AND METHOD THEREOF - A dosing device for an infusion system comprises a dosing unit having a variable volume and at least one opening in fluid connection with the variable volume, through which opening the variable volume can be filled with a substance or the substance can be dispensed from the variable volume. The dosing device is operable in a first state for filling the substance from a supply conduit, in a second state for preventing filling and dispensing, or in a third state for dispensing through a dispensing conduit. No direct fluid connection exists between the supply conduit and the dispensing conduit at any time. Methods for dosing a substance with the dosing device.08-25-2011
20110224642SYRINGE WITH FLOW CONTROL VALVES AND ASSOCIATED METHODS - The present invention includes syringes with valves. The valves control communication between the interior of a barrel of the syringe and the exterior of the barrel. In syringes that include two valves, the valves may be oriented opposite one another, such that one of the valves may enable fluid to flow into the interior of the barrel of the syringe while preventing fluid from flowing in the opposite direction, while the other valve may enable fluid to flow out of the interior of the barrel while preventing fluid from flowing in the opposite direction. Alternatively, a syringe may include a single valve, which is carried at or near a distal end of its plunger. Methods for using such syringes, including, but not limited to, manual pulsed aspiration methods and manual pulsed delivery methods are also disclosed.09-15-2011
20100004622METHOD EMPLOYING A DRAINAGE CATHETER ASSEMBLY FOR DELIVERING A CATHETER TO A BODY - A method for employing a pre-assembled drainage catheter assembly for the insertion of a drainage catheter percutaneously. The assembly includes a trocar, a cannula, a catheter stiffener, and a catheter. The drainage catheter assembly is operated between a pre-assembled condition, a first step condition and a second step condition. In the first step insertion the trocar and cannula are inserted into a patient's body for obtaining a specimen fluid before the catheter is inserted. In the second step the catheter is inserted for collecting fluid.01-07-2010
20090005754Distal wire stop having adjustable handle - A method and apparatus for releasably securing a wire guide to an elongate medical device for introduction into a work site with the bodily lumen of a patient. An elongate engagement member is configured to engage the wire guide while it is coupled to the elongate medical device and is configured so as to prevent relative movement between the wire guide and the elongate medical device. The elongate engagement member includes an adjustable handle assembly for adjusting the relative position of the distal end of the elongate engagement member relative to the elongate medical device.01-01-2009
20110224645TREATING INFLAMMATORY CONDITIONS - An apheresis column loaded with a solid support comprises one or more chemokines, in particular biotinylated chemokines, immobilized directly or indirectly on the support, in particular on a support carrying streptavidin. Also disclosed are uses of the column and the support and a method of depleting cells, in particular leukocytes, from the peripheral blood of a person suffering from an inflammatory condition such as Inflammatory Bowel Disease (IBD).09-15-2011
20110224643PRE-FILL SYRINGE - A pre-fill syringe with a receiver tube (09-15-2011
20090326508METHOD AND APPARATUS FOR DELIVERING OXYGEN AND/OR OTHER GASES AND/OR PHARMACOLOGICAL AGENTS TO TISSUE - A system comprising: 12-31-2009
20130218125Implantable Devices Including A Mesh And A Perforated Film - The present disclosure relates to implantable medical devices which include at least one mesh and at least one perforated film positioned on the mesh, wherein a portion of the film is positionable away the mesh to allow direct treatment of the contacting mesh tissue and the distal wound or incision site.08-22-2013
20120095434METHODS AND DEVICES FOR PERICARDIAL ACCESS - Devices and methods for accessing the pericardial space of a heart are described here. Access devices may generally comprise a tissue-engaging member, a tissue-piercing member, and a guide element. The access device may be introduced to the surface of a pericardium, where the tissue-engaging member may be deployed to engage a portion of the pericardium without engaging the epicardial surface of the heart. Once the access device has engaged the pericardium, the device may manipulate the pericardium to increase the distance between a portion of the pericardium and the epicardial surface of the heart. Once a sufficient space has been created, the tissue-piercing member may be advanced to pierce the pericardium and enter the pericardial space. The guide element may then be introduced into the pericardial space to provide an access pathway to the heart for other devices.04-19-2012
20090318886MEDICAL DEVICE - An implantable medical device can be configured to directly or indirectly release nitric oxide during its insertion in a patient. Such a device can reduce the amount of time required for implantation as well as reduce or prevent damage to the region surrounding the implanted device.12-24-2009
20090299326ENDOVASCULAR ANEURYSM TREATMENT DEVICE AND METHOD - An self-expanding frame is mounted on the distal end of a shaft. The frame is sized and configured so that it can be inserted into the cavity of an aneurysm. Suction is applied to the interior of the aneurysm through the shaft or through another catheter, and the wall of the aneurysm is collapsed onto the exterior surface of the frame. The frame is then collapsed upon further suction being applied to the interior of the aneurysm, which collapses the aneurysm wall with it. The frame folds down on itself, carrying with it the aneurysm wall. The frame is detachable from the shaft and can be left in the collapsed aneurysm.12-03-2009
20090198209FLUID MANIFOLD CONTROL DEVICE - A manifold is disclosed which includes a manifold body that defines a main lumen, a primary injection line and a port. A check valve system is also provided which permits flow from the primary injection line to the main lumen while selectively preventing back flow from the main lumen to the primary injection line and, simultaneously, permitting flow from the port to the primary injection line while preventing back flow from the primary injection line to the port.08-06-2009
20090082753NEEDLE FREE INJECTOR WITH DOSE ADJUSTMENT ASSEMBLY - A needle-free injector with a mechanism to adjust the volume of liquid administered is provided. The injector includes a power base, a fluid path having a plunger to force substances from a cavity defined within the fluid path, and a dose adjustment assembly for adjustably positioning the fluid path relative to the power base to adjust the volume of substance administered to the subject.03-26-2009
20120078220CATHETER ASSEMBLY - Devices and methods are provided to conduct fluid away from or deliver fluid to an area of a treatment site of a patient's body. In one aspect of the invention, a catheter includes a terminal end with a fluid exchange portion. The terminal end may further include a diffuser. The terminal end may further include a barrier.03-29-2012
20120078219Syringe Assembly - A syringe assembly includes a syringe body having an internal fluid reservoir and a fluid contained within the fluid reservoir and defining a fluid outlet adjacent the distal end thereof, a plunger at least partially disposed within the syringe body and having a plunger rod and a distal plunger head and being adapted for longitudinal movement from an initial retracted position to an actuated advanced position and a dispensing element disposed within the internal fluid reservoir of the syringe body and distal of the plunger head. The dispensing element is dimensioned and arranged to cooperate with the plunger head to permit engagement and advancing movement of the dispensing element during corresponding movement of the plunger head without effecting a coupling relationship with the plunger head whereby the plunger is movable toward the retracted position without causing corresponding movement of the dispensing element.03-29-2012
20120078218MODULAR INFUSION SYSTEM - A pump is disclosed that comprises a primary control unit comprising a first processor and one or more modular pumping units removably docked to the primary control unit. Each modular pumping unit comprises a pumping mechanism and a second processor configured to control the pumping mechanism and communicate with the first processor. The modular pumping unit is configured to manipulate a portion of a fluid delivery set to pump a fluid. The first processor and the second processor are configured to exchange one or more operating parameters when the modular pumping unit is docked to the primary control unit. The modular pumping unit is configured to pump the fluid after being undocked.03-29-2012
20120078217INFUSION PUMPS - Ambulatory infusion pumps, pump assemblies, cartridges, baseplates, cannulas, insertion tools, and related components as well as combinations thereof and related methods.03-29-2012
20120078216INFUSION PUMPS - Ambulatory infusion pumps, pump assemblies, cartridges, baseplates, cannulas, insertion tools, and related components as well as combinations thereof and related methods.03-29-2012
20080262467Blood Flow Bypass Catheters and Methods for the Delivery of Medium to the Vasculature and Body Ducts - A catheterization device that may be designed by use of an adaptive genetic algorithm computational fluid dynamics approach, as well as other Global Optimization methods that may include simulated annealing, multistart and interval methods, con-tinuous branch and bound methods, evolutionary algorithms, and tabu search and scatter search methods, as well as other available Global Optimization methods that is able to maximize/optimize the dwell time of an infused agent in the vicinity of a vascular lesion. The device may have an internal by-pass channel that allows the blood upstream of the lesion to continue its pulsatile flow through the vessel in the part of it occluded by the lesion, while simultaneously allowing the disbursement and maximal dwell time of an antithrombolytic or other diagnostic or therapeutic agent needed to treat the lesion. Different embodiments of the catheterization device are disclosed and indications for the use of these devices in the treatment of vascular diseases are discussed.10-23-2008
20110144617MEMS DEVICE AND METHOD FOR DELIVERY OF THERAPEUTIC AGENTS - Embodiments of an implantable device for delivering a therapeutic agent to a patient include a reservoir configured to contain a liquid comprising the therapeutic agent, a cannula in fluid communication with the reservoir, and means for forcing fluid from the reservoir into the cannula. Circuitry for controlling the means for forcing fluid from the reservoir into the cannula may be included.06-16-2011
20110144616INFUSION PUMP SYSTEM WITH DISPOSABLE CARTRIDGE HAVING PRESSURE VENTING AND PRESSURE FEEDBACK - Embodiments are directed to portable infusion devices, systems, and methods of using the same for dispensing materials. In some cases, the devices, systems and methods may be used for infusing a material such as medicament, e.g., insulin, into a body in need thereof.06-16-2011
20110144615METHOD AND DEVICE FOR MICRO-DOSING A LIQUID - Methods and devices for micro-dosing a liquid are disclosed herein. According to one embodiment, a method for a time controlled micro-dosing of a liquid from a liquid reservoir includes: receiving the liquid reservoir with a structure wherein the structure is portable; securing the liquid reservoir to the structure; connecting a second end of a drive unit to a piston disposed within the liquid reservoir; activating a drive motor; displacing the drive unit with respect to the structure towards the piston in an axial direction with the drive motor; moving the piston axially within the liquid reservoir; and micro-dosing the liquid from the liquid reservoir.06-16-2011
20090209936ASPIRATOR AND METHOD FOR PNEUMOSTOMA MANAGEMENT - A method for treating a pneumostoma by applying suction to the pneumostoma in order to remove solid or liquid discharge. A pneumostoma aspirator including a bulb or syringe is used to apply negative pressure to a tube which enters the pneumostoma. The pneumostoma aspirator may be used in conjunction with a pneumostoma management device. Alternatively, the pneumostoma aspirator may be used after the pneumostoma management device has been removed. The pneumostoma aspirator may also be used to introduce irrigation fluid into the pneumostoma and/or remove irrigation fluid and discharge from the pneumostoma.08-20-2009
20090157039INJECTION DEVICE AND AMPOULE UNIT - The invention relates to an injection device for the needle-free injection of a medium. Said injection device comprises an injector device and an ampoule unit, said ampoule unit comprising a base (06-18-2009
20090240230Intradermal Needles Injection Device - A needle-less fluid injection device, including, a nozzle head with an injection hole for accepting a dose of fluid to be injected into the skin of a patient, a fluid capsule that is connected to said nozzle head and provides the nozzle head with one or more doses of fluid for injection, an injection head for mounting the fluid capsule and the nozzle head; including a first mechanism for releasing a dose of fluid from the fluid capsule to the nozzle and a second mechanism for injecting the dose of fluid from the nozzle into the skin of a patient.09-24-2009
20090192485SNARE DEVICE - An apparatus and method for removing an object from a tubular vessel are disclosed. The apparatus includes an expandable catheter and a plurality of wires configured to snare an object within a tubular vessel. A distal end of the expandable catheter may be manipulable between a first configuration wherein an opening thereon has a first diameter, and a second configuration wherein the opening has a second diameter which is larger than the first diameter. The apparatus may further include an inner catheter within its lumen, the inner catheter being extendable from the expandable catheter's lumen. The apparatus may additionally or alternatively include an outer catheter having a lumen from which the expandable catheter may be expanded.07-30-2009
20090247982Medical Device Mechanical Pump - A medical device pump with a housing with a compartment for removably receiving a cartridge containing a therapeutic agent, a conduit configured to operatively provide a fluid flow path for therapeutic agent to exit from the cartridge, a user activated delivery button, a trigger mechanism, and a mechanical pump mechanism. The trigger mechanism, user activated delivery button and mechanical pump mechanism of the medical device pump are configured such that the trigger mechanism is activated by a user fully activating the user activated delivery button. Moreover, such full activation generates mechanical power employed by, and sufficient for, the mechanical pump mechanism to pump a predetermined volume of therapeutic agent from the cartridge and through the fluid flow path.10-01-2009
20100274215FLUSHING SOLUTION - A flushing solution is described which is suitable for use in surgical, in particular ophthalmological, operations and which contains a non-Newtonian fluid. The use of such a flushing solution is also described.10-28-2010
20100160891ELASTIC IMPLANTABLE COMPOSITES AND IMPLANTS COMPRISING SAME - Described herein are implantable composites, kits comprising the composites, implant devices comprising the composites, and methods of making and using same, including point of use methods.06-24-2010
20110060308METHODS AND IMPLANTS FOR INDUCING SATIETY IN THE TREATMENT OF OBESITY - A method for inducing satiety using the steps of inserting an elongated device into a patient through a natural orifice and into a stomach of the patient, placing a distal end of the elongated device adjacent a treatment site within the stomach, and delivering at least one space occupying member through the elongated device adjacent the treatment site and implanting the at least one space occupying member between the submucosal and muscularis layers at the target site.03-10-2011
20100191215PRESSURE PULSE ACTUATING DEVICE FOR DELIVERY SYSTEMS - A system and method for delivering medicament to tissue, using a pulse pressure source and optional pre-pressuring. Optionally, the delivery system is modular and/or adjustable for various applications. Optionally, the treated tissue is a blood vessel wall. Optionally, the delivery system is mechanical.07-29-2010
20100217228Convection-Enhanced Delivery Catheter with Removable Stiffening Member and Method for Using Same - A catheter for delivering an agent to targeted tissue of a mammalian body including a first elongate tubular member having a proximal opening and a distal end wall. A second elongate tubular member having a portion extends through first elongate tubular member and has a distal end extending beyond the end wall. The first and second tubular members form an annular cavity within the first tubular member. A stiffening member has at least a portion disposed within the annular cavity for facilitating accurate placement of the distal end relative to the targeted tissue in the mammalian body and is removeable from the annular cavity after such placement without removal of the second elongate tubular member from the mammalian body. A method is provided.08-26-2010
20100204673OBESITY CONTROLLING METHOD - A method of controlling obesity by injecting bio-compatible bulking material into the pyloric sphincter area of the stomach. The injection of this material bulks the pyloric sphincter, retarding stomach emptying and producing a feeling of satiation in the patient. The method may be supplemental and augmented by inducing flacid paralysis of the stomach by injecting botulinum toxin into the muscle tissue of the antrum or fundus of the stomach.08-12-2010
20100228224SURGICAL FLUID MANAGEMENT SYSTEM CONTROL AND DEFICIT MONITORING - Surgical fluid management systems and methods of operating surgical fluid management systems which may provide one or more functions associated with suction, irrigation, distention, deficit monitoring, infusion, fluid warming, and the like. Some example embodiments may include infra-red lamps arranged to heat fluid flowing through a disposable cartridge. Some example embodiments may provide a three-dimensional fluid path through the cartridge and/or multi-stage heating capabilities. Some example fluid management systems may be selectable between pressure control and flow control modes.09-09-2010
20100228222SURGICAL FLUID MANAGEMENT SYSTEM WITH PRESSURE AND/OR FLOW CONTROL - Surgical fluid management systems and methods of operating surgical fluid management systems which may provide one or more functions associated with suction, irrigation, distention, deficit monitoring, infusion, fluid warming, and the like. Some example embodiments may include infra-red lamps arranged to heat fluid flowing through a disposable cartridge. Some example embodiments may provide a three-dimensional fluid path through the cartridge and/or multi-stage heating capabilities. Some example fluid management systems may be selectable between pressure control and flow control modes.09-09-2010
20100228223SURGICAL FLUID MANAGEMENT SYSTEM HEATER ASSEMBLY AND CARTRIDGE - Surgical fluid management systems and methods of operating surgical fluid management systems which may provide one or more functions associated with suction, irrigation, distention, deficit monitoring, infusion, fluid warming, and the like. Some example embodiments may include infra-red lamps arranged to heat fluid flowing through a disposable cartridge. Some example embodiments may provide a three-dimensional fluid path through the cartridge and/or multi-stage heating capabilities. Some example fluid management systems may be selectable between pressure control and flow control modes.09-09-2010
20100228221DEVICES, SYSTEMS, AND METHODS FOR OBTAINING BIOPSY TISSUE SAMPLES - Devices, systems, and methods for accessing tissue in a minimally invasive manner and taking a biopsy tissue sample therefrom are disclosed. At least some of the embodiments disclosed herein enable a tissue sample to be taken from the external surface of the heart in a non-invasive manner. In addition, various disclosed embodiments provide devices, systems and methods for accessing the pericardial space through the interior of the heart and engaging the epicardial surface and removing a tissue sample therefrom for diagnostic purposes through the use of suction.09-09-2010
20100217229BUBBLE FREE-SELF PRIMED IV SET - A bubble free, self-priming IV set for use in the administration of liquids that includes a drip chamber comprising a chamber inlet and a chamber outlet, a bubble isolation device disposed within the drip chamber that prevents air bubbles from exiting the chamber outlet, a tube having an inlet end coupled to the chamber outlet of the drip chamber and an outlet end, and an end plug that includes an air vent. The end plug may be coupled to the outlet end of the tube and is a flow restrictor so that when a liquid is moving through the tube, the velocity of the liquid flow is controlled such that the front of the liquid does not trap bubbles in the tube.08-26-2010
20120130339Multi-Dose Drug Delivery Device and Method - Drug delivery devices and methods are provided. The device included two or more housing units connected together end-to-end in a fixed, linear orientation, the exterior surfaces of the connected housing units defining a sidewall of the device; discrete drug dose units disposed within the housing units; degradable timing members connected to the housing units and separating the discrete dose units from one another; first and second end pieces defining opposed ends of the device such that the discrete dose units are located between the first and second end pieces within each of the housing units, wherein the device is configured to release in vivo a first of the discrete dose units following rupture of the first or second end piece, and subsequently to release in vivo a second of the discrete dose units following rupture of the degradable timing member separating the first discrete dose unit from the second discrete dose unit.05-24-2012
20120130338DIAPHRAGM PRESSURE POD FOR MEDICAL FLUIDS - A tubular medical fluid flow set comprises a pressure sensing chamber connected in flow-through relation to fluid flow tubing of the set. The pressure sensing chamber defines a movable, flexible, impermeable diaphragm dividing the chamber into two separate compartments. The fluid flow tubing communicates with one of the compartments and is isolated from the other of the compartments. A port is carried on the chamber, the port having a seal therein, and communicating with the other of the compartments. Thus, the other of the compartments is hermetically sealed until the port is opened for connection with a pressure measuring device, to keep the flexible diaphragm in a desired, initial position prior to opening of the seal.05-24-2012
20090076477Automatic Liquid Injection System and Method - A power assisted method and injector device for controllably delivering to patients a dispersion medicament or diagnostically active agent, the homogeneity of which is preserved throughout delivery. Diagnostically active agents disclosed are gas microbubble suspensions useful in ultrasonic diagnostic imaging and liposomal formulations in which liposome vesicles are loaded with iodinated compounds.03-19-2009
20090076476SYSTEMS AND METHODS EMPLOYING FORCE SENSING FOR MAPPING INTRA-BODY TISSUE - A medical instrument system includes a controller and a guide instrument coupled to an instrument driver, the instrument driver configured to manipulate a distal end portion of the guide instrument in response to control signals generated by the controller. A force sensor is associated with the guide instrument or with a working instrument carried by the guide instrument, and generates force signals responsive to a force applied to a respective distal end portion of the guide instrument or working instrument. A position determining system generates position data indicative of a position of the respective guide or working instrument distal end portion associated with the force sensor, and a processor operatively coupled to the force sensor and position determining system processes respective force signals and position data to generate and display a geometric rendering of an internal body tissue surface based on sensed forces applied to the respective instrument distal end portion as the guide instrument is maneuvered within an interior region of a body containing the body surface.03-19-2009
20090076478CATHETER FOR UNIFORM DELIVERY OF MEDICATION - A catheter is provided for uniform distribution of fluid medication within an anatomical region. One embodiment of the catheter is compromised of an elongated, proximal tube defining a lumen and an elongated, distal tube having a closed end. The distal tube is constructed from a bio-absorbable material and also defines a lumen, which communicates with the lumen of the proximal tube. In one embodiment, at least a portion of the distal tube defines a porous side wall that permits fluid within the lumen to pass through the portion of the distal tube. In another embodiment, the proximal tube and the distal tube overlap one another and are secured to one another at the overlapping surfaces.03-19-2009
20110112504Operating an Infusion Pump System - Some embodiments of a medical infusion pump system include a pump device having a cap device that mates with a pump housing to retain a medicine cartridge therein. In addition to retaining the medicine cartridge in the pump housing, the cap device may perform a number of preparatory functions or safety functions. In addition or in the alternative, some embodiments of the pump device may include a drive system that advances a piston rod to dispense medicine to the patient in a safe and energy efficient manner.05-12-2011
20100152698ANTI-THROMBOGENIC CATHETER AND METHOD - A medical catheter assembly is provided including an inner catheter member, where that inner catheter member includes a plurality of inner catheter lumens, and an outer sheath with at least one patent sheath lumen. The inner catheter is slidably disposed through a length of the at least one patent sheath lumen in a manner providing a substantially sealing contact between an exterior surface of the inner catheter and an inward surface of the at least one patent sheath lumen. A first of the plurality of inner catheter lumens includes a plurality of apertures to the exterior surface of the inner catheter, and a second of the plurality of inner catheter lumens includes at least one distal end-tip opening. A method of using the assembly is also provided.06-17-2010
20100222766INVENTORY SPARING CATHETER SYSTEMS AND METHODS - Some embodiments relate to a catheter system having a changeable or adjustable working length. The catheter system can comprise a proximal end, a distal end, and a first axial lumen configured to receive a guidewire formed through at least a portion of the catheter body. A first opening can be formed through a portion of the catheter body and be in communication with the first lumen. The sheath can be rotatable, axially movable, or otherwise changeable from at least a first position to a second position, wherein the sheath can substantially cover the first opening in the catheter body in the first position, and can substantially expose the first opening in the catheter body in the second position.09-02-2010
20100222764Intracranial Catheter and Methods of Use - A catheter assembly for intracranial treatment of a subject that includes an outer tube that may be connected to an infusion or osmotic pump and delivered through a bendable catheter to the target brain site of the subject. The assembly facilitates regular accurate placement of drug or compound delivery at the tissue region without additional contact and minimizes trauma to the subject.09-02-2010
20100222765CORRECTION FACTOR TESTING USING FREQUENT BLOOD GLUCOSE INPUT - An apparatus comprises receiving a user prompt in a blood glucose (BG) management device to start a determination of an effective correction factor, receiving sampled blood glucose data of a patient obtained during a specified time duration, including a time duration after delivery of an initial insulin correction bolus, determining the effective correction factor using the BG management device according to a determined decrease in the blood glucose level of the patient and an amount of insulin in the initial insulin correction bolus, and cancelling the determination of the effective correction factor if a blood glucose level of the patient is outside of a specified range of blood glucose levels.09-02-2010
20120143167Methods For Improved Cryo-Chemotherapy Tissue Ablation - The current invention relates to a process for increasing the efficacy of cancerous disease inhibiting therapeutic agents delivered to a treatment region of a tissue structure, such as a tumor. The multi-step procedure takes advantage of the resulting thermal stress response occurring as a result of exposure to the cold. Coordinating the thermal related stress response with the timing of cancerous disease inhibiting agent action provides a unique therapeutic regiment to treat tumors which provides a maximized effect on the tumor, protects normal cells, and activates local pro-inflammatory cells.06-07-2012
20100198186DUAL-LUMEN CATHETER FOR MEDICAL DEVICE DELIVERY SYSTEMS - A catheter assembly having a dual lumen proximal tubular portion including a guidewire lumen and an inflation lumen and a single lumen distal tubular portion that receives the guidewire and can additionally receive fluid. The catheter assembly includes flow passages in allow fluid to flow from the interior of the catheter to the exterior.08-05-2010
20120245553INTRAGASTRIC VOLUME OCCUPYING DEVICE WITH ACTIVE AGENTS - An implantable intragastric volume occupying device system is provided which generally includes a volume occupying device and an active agent, for example, a metabolic agent or satiety inducing agent. The volume occupying device may be structured to contain the agent and permit controlled release of the agent to the patient while the volume occupying device is positioned within the patient's stomach. Methods for treating obesity are also provided which include positioning a volume occupying device in the stomach of a patient and administering a satiety inducing agent to the patient while the volume occupying device is positioned in the stomach. In one embodiment, the active agent may be contained in a reservoir and dispensed to a portion of the patient's body.09-27-2012
20090204099Cervical dilating and ripening catheter system and method - A cervical dilating and ripening catheter system includes an elongated tube having a first end and a second end, and a first expandable portion affixed to the second end of the elongated tube. The system also includes a second expandable portion disposed between the first expandable portion and the first end of the elongated tube. The system further includes means for distributing a cervical ripening medication to the cervix.08-13-2009
20090112177Implantable Device And Method for Delivering Drug Depots To A Site Beneath the Skin - An implantable device and method is provided for anchoring a drug depot to a site beneath the skin of a patient, the device and method comprising a head, a shaft and a tip, the head having a recess and/or at least one projection arranged to be engaged by an implantation tool, the shaft having an outer surface that engages the site in a manner that holds the device at the site beneath the skin, the head or shaft having means for attaching the drug depot thereto, and the tip disposed on the shaft opposite the head and capable of insertion into the site beneath the skin of the patient.04-30-2009
20130131626INFLATION CUFF WITH TRANSIENT-RESISTANT OVER-PRESSURE PREVENTOR - A catheter system (05-23-2013
20130131627Device for Passively Removing a Target Component from Blood or Lymph of a Vertebrate Subject - Devices, systems, and methods are described herein for controlling or modulating the levels of one or more target components in the blood and/or lymph of a vertebrate subject. Devices and systems are provided that include a body defining at least one lumen configured for fluid flow; at least one controllable flow barrier to fluid flow into the at least one lumen; at least one first reservoir disposed within the body and configured to include one or more bifunctional tags, wherein the one or more bifunctional tags are configured to selectively bind to one or more target components in one or more of blood fluid or lymph fluid of a vertebrate subject; at least one treatment region disposed within the at least one lumen; and at least one second reservoir disposed in the at least one treatment region and configured to include one or more reactive components, wherein the one or more reactive components are configured to sequester the one or more bifunctional tags when bound to the one or more target components.05-23-2013
20090069786Medical apparatus and method for facilitating the management of long term tunneled conduits - A method and apparatus for facilitating the management of indwelling conduits to avoid and/or treat infections associated with long term implantation. A sleeve carrying a layer of porous material on its outer surface is percutaneous implanted to place the layer of porous material just under the patient's outer skin in contact with the patient's dermis where it functions to promote soft tissue ingrowth. A catheter passes through the sleeve passageway and along an interior body path to an interior destination site, e.g., an opening into a vein, i.e., venotomy site. Within about 3-6 weeks after implantation, the patient's dermal tissue integrates sufficiently with the sleeve porous material to physically anchor the sleeve and create an infection resistant barrier. Further, a tunnel, characterized by an epithelialized capsule, typically forms around the catheter along the interior body path extending to the interior destination site. After sufficient integration of the patient's soft tissue into the porous layer, the sleeve passageway can be used to pass various procedural tools to the tunnel and interior destination site without disturbing the tissue integrating barrier.03-12-2009
20090069785User Profile Backup System For an Infusion Pump Device - Some embodiments of an infusion pump system can include a controller device that communicates with a pump device, the pump device having a memory device. The controller device can be configured to record controller-related data, such as user profile data on the memory device of the pump device. This user profile data that is stored in the memory of the pump device can serves as a data backup system that permits the user to program a new controller device in a situation where the original controller device is lost or damaged. In addition or in the alternative, the controller device can be configured to receive controller-related data, such as software update programs or backup controller data, from the memory device of the pump device.03-12-2009
20090069784Controlled Adjustment of Medicine Dispensation from an Infusion Pump Device - Some embodiments of an infusion pump system can incorporate an accelerometer or other motion sensor to detect the user's activity level. If the user's activity level indicates that he or she is exercising or otherwise at an elevated level, the infusion pump device can be configured to automatically adjust the dispensation rate of a medicine such as insulin. Accordingly, an insulin delivery rate can be corrected to account for a user's activity level (e.g., an elevated activity level during exercise or the like).03-12-2009
20110172634INJECTION SYSTEMS - The invention in general relates to various injection systems and devices that can be used, for example, in needleless injection systems for human, and for domestic and farm animals. In certain embodiments, the invention provides an injection system comprising: an injector defining a first cavity in fluid communication with an orifice configured for needleless injection; a housing defining a second cavity, the housing different than the injector; a first movable member between the first cavity and the second cavity, wherein the first movable member is configured to transfer a fluid from the second cavity to the first cavity; and wherein the first movable member is configured to be substantially stationary until the first movable member is moved by a propellant.07-14-2011
20110172633THERAPY SYNCHRONIZATION - A system employing multiple implantable therapy delivery devices may be configured to provide coordinated or synchronized therapy by allowing the devices to communicate with each other, directly or indirectly. Fault tolerance or redundancy may be incorporated into the system to allow for correction of failed devices in real time or pseudo real time.07-14-2011
20110172631NEEDLELESS INJECTION DEVICE COMPONENTS, SYSTEMS, AND METHODS - A high-pressure fluid injection system, which includes a rechargeable injection chamber with a proximal end, a distal end, and an internal opening extending from the proximal end to the distal end, a plunger slideably engaged with the internal opening of the injection chamber, an injection tube extending from the distal end of the injection chamber and in fluidic communication with the internal opening of the injection chamber, and a check valve between the proximal and distal ends of the injection chamber. The internal opening includes a high-pressure zone adjacent to the check valve and having a first diameter, and a low-pressure zone proximal to the high-pressure zone and having a second diameter that is larger than the first diameter.07-14-2011
20130138075VARIABLE FLOW CONTROL DEVICE, SYSTEM AND METHOD - A device, system and method are provided for controlling the rate of infusion of fluids during infusion therapy using non-electric infusion devices. Rotation of a flow regulator dial causes an orifice connected to the inlet to modify its position relative to a particular one or more orifices or groove portions, the characteristics of which provide a certain flow rate characteristic. The regulator allows for the infusion pump to infuse at a rate that may be varied during use by the user.05-30-2013
20130138076DRUG DELIVERY METHOD - A drug delivery device mainly has a housing, which can be easily held and operated. The housing has one end formed with an adjustment seat capable of adjusting a range distance, and the other end connected to a gas pressure control source for providing mainstream and substream gas pressures. Disposed in the housing are a drug delivery pressuring tube, an embedded drug-can connecting seat or an external drug-can connecting seat, a replaceable drug-can container and a gas communication tube. According to this design, the minor liquid drug can be controlled, the drug-can can be replaced and the continuous quantitative injection of drug can be made. Also, all damaged or dirty members of the invention may be disassembled, cleaned or replaced.05-30-2013
20130138077INFUSION CATHETER AND METHODS - An infusion catheter includes an elongate catheter body having a longitudinally extending fluid supply passage, and a plurality of stellate side ports for infusing a treatment fluid from the fluid supply passage into a body lumen of a passage. Each of the stellate side ports is defined by sets of at least three convergent leaves having an attached basal edge, a terminal tip, and first and second free edges extending between the attached basal edge and the terminal tip. Making an infusion catheter includes forming a plurality of stellate side ports in fluid communication with a fluid supply passage of an elongate catheter body, each of the stellate side ports being defined by a set of at least three convergent leaves, and setting an infusion length of the infusion catheter during the forming step via spacing the stellate side ports between proximal and distal ends of the elongate catheter body.05-30-2013
20090036867Medication Delivery Device Applying A Collapsible Reservoir - The present invention relates to a medication delivery device comprising pump means and a reservoir adapted for containing a medicament. The pump means is adapted to transfer the medicament from the reservoir to an outlet arrangement, said outlet arrangement being adapted to be operatively connected to an associated hypodermic needle. The pumps means is adapted to deliver a set dose of medicament during one or more pump strokes, wherein the stroke volume(s) of said one or more pump strokes is variable. The present invention further relates to a method for adjusting stroke volumes to a set dose of medicament.02-05-2009
20130144249ADHESIVE DELIVERY DEVICES, SYSTEMS AND METHODS - Devices, systems and methods are disclosed for delivering adhesive material to a patient site. A delivery device includes a housing and a nozzle. Adhesive material exits the end of the nozzle such as to adhesively attach tissue to tissue or a material or device to tissue.06-06-2013
20130144252NEEDLESS MICROPROTRUSION ELASTOPLAST SYSTEM - A needleless microprotrusion system for infusion of a medicament into a patient includes a plurality of microprotrusions having a length sufficient to penetrate a stratum corneum of the patient. A chemodenervating agent is disposed for delivery by the microprotrusions and a substrate is provided for supporting the microprotrusions and conforming the microprotrusions to a patient's fossa axilaaris in order to enable uniform penetration of the microprotrusions into the corneum.06-06-2013
20100331809CONFORMABLE STENTS AND METHODS FOR MAKING - Materials and methods for making conformable stents. The stents can be generated by, for example, injecting a fluid into a scaffold on the outer surface of an angioplasty balloon inflated at the site of a stenosis, and allowing the fluid to harden or set, thus generating a stent that can remain in the vessel at the site of stenosis.12-30-2010
20100331807TREATMENT OF MOVEMENT DISORDERS BY BRAIN STIMULATION - Systems for treating a movement disorder include a system control unit configured to be implanted at least partially within a patient and to generate at least one stimulus in accordance with one or more stimulation parameters adjusted to treat the movement disorder. The systems further include a programmable memory unit in communication with the system control unit and programmed to store the one or more stimulation parameters to at least partially define the stimulus such that the stimulus is configured to treat the movement disorder. A means for applying the stimulus to one or more stimulation sites within the patient is operably connected to the system control unit.12-30-2010
20100331808Dispenser and Method for Storing and Dispensing Sterile Product - A dispenser is provided for the delivery of controlled, metered amounts of any of numerous different substances to humans or animals, such as medicaments, pharmaceuticals, cosmetics, and food products, or to deliver materials that may react upon exposure to air, such as glue. Means are provided in the dispenser to effect controlled delivery of a pre-determined amount of the substance contained in the dispenser. A one-way valve is provided to hermetically seal the portion of the dispenser containing the substance to be dispensed.12-30-2010
20100331806DRIVE MECHANISM FOR A DRUG DELIVERY DEVICE - A dose setting mechanism for a drug delivery device is disclosed. The mechanism comprises an outer housing and an inner housing having an external groove. The inner housing guides a driver having either a blocking or locking member disposed inside the driver that can lock a flexible tab to an internal groove during dose delivery in the inner housing such that the driver follows the path of the groove and to advance a spindle to move a cartridge bung. A dial sleeve is disposed between the outer and inner housing and is rotatably engaged with the inner housing.12-30-2010
20100198187VENTED DISPENSING DEVICE AND METHOD - Disclosed is a fluid dispensing device that includes at least one reservoir to hold the therapeutic fluid, at least one other unit requiring communication with ambient air, at least partly, to operate, and at least one housing defining an interior to retain the at least one reservoir and the at least one other unit. The at least one housing has at least one vent port formed on one or more of its walls. The at least one vent port is adapted to direct or communicate air to maintain pressure equilibrium between the air pressure in the interior of the at least one housing and the ambient air pressure outside the at least one housing, and provide communication with the ambient air to the at least one other unit requiring air to enable operation of the at least one other unit.08-05-2010
20100262116SYSTEMS AND METHODS FOR PATIENT CARDIOVASCULAR AND RESPIRATORY MANAGEMENT - An information display and control system that enables a fast and easy understanding and management of the status of the patient's cardiovascular and ventilation systems is disclosed. The system can control administration and management of a patient's medication and fluids. The display is organized by goals related to management of patient's cardiovascular system, ventilation system, and medications and fluids administration and management. Such goals include hemodynamics, oxygenation, CO10-14-2010
20110009846MODULAR EXTERNAL INFUSION DEVICE - A modular external infusion device that controls the rate a fluid is infused into an individual's body, which includes a first module and a second module. More particularly, the first module may be a pumping module that delivers a fluid, such as a medication, to a patient while the second module may be a programming module that allows a user to select pump flow commands. The second module is removably attachable to the first module.01-13-2011
20110130741SENSORS FOR DETECTING GAS IN, AND PRESSURE OF, A LIQUID - A sensor comprises a body having a channel adapted to receive a hose, the channel comprising opposed fixed walls, a transmitter in one of said walls and a receiver in the opposed wall, and a pressure sensor disposed between the opposed walls.06-02-2011
20110130742DISPOSABLE INFUSION DEVICE FILLING APPARATUS AND METHOD - An infusion system includes a disposable wearable infusion device and a filler device. The disposable infusion device has a body arranged to be adhered to a patient's skin and a reservoir for holding a liquid medicant to be infused into the patient. The filler device is arranged to detachably receive the infusion device body and to transfer a volume of the liquid medicant to the infusion device reservoir. The filler device may be part of a service device arranged to detachably receive the infusion device and which also includes a cannula driver and a cannula for providing the infusion device with a cannula and deploying the cannula to beneath a patient's skin.06-02-2011
20110034900DEVICES AND METHODS FOR IMPROVING ACCURACY OF FLUID DELIVERY - Devices and methods for delivering therapeutic fluid to a patient's body are described. The devices may comprise a dispensing unit having a reservoir, a driving mechanism having a movable member for delivering therapeutic fluid to a patient's body, at least one sensor for sensing a relative position of the movable member and generating a signal, and a processor for controlling the driving mechanism to deliver an amount of therapeutic fluid that compensates for a change in the flow of the therapeutic fluid occurring during fluid delivery. The methods may be implemented by operating the driving mechanism, receiving a signal based on the position of the movable member, determining an amount of therapeutic fluid to deliver, and controlling the driving mechanism to deliver an amount of fluid that compensates for a change in flow occurring during fluid delivery.02-10-2011
20110040278DEVICE AND METHOD FOR FABRICATING CELLULARIZED IMPLANTS WITH A PREDETERMINED ARCHITECTURE AT THE POINT OF CARE - In some embodiments, a method of repairing damaged tissue may include an implant system and method for preparing and using said implant. In some embodiments, a method of repairing damaged tissue may include injecting a first portion of biological material through a first opening in fluid communication with a first end of at least two first channels. In some embodiments, the method may include injecting a second portion of biological material through a third opening in fluid communication with a first end of a sheath. At least a portion of the first channels may be positionable in at least a portion of the sheath. The method may include coupling at least a portion of the sheath and/or at least a portion of at least one of the first channels to at least a portion of a damaged tissue in a human.02-17-2011
20110112503CHEMISTRODE, A PLUG-BASED MICROFLUIDIC DEVICE AND METHOD FOR STIMULATION AND SAMPLING WITH HIGH TEMPORAL, SPATIAL, AND CHEMICAL RESOLUTION - A method for sampling and/or introducing a matter to an environment comprises introducing a first array of plugs through a first microchannel of a device into an exchange region of the device in which mass transport between the environment and the plug fluid of at least one plug in the first array of plugs occurs and a second array of plugs is formed. The exchange region is in fluid communication with the first microchannel. The method further comprises directing the second array of plugs into a second microchannel downstream of and in fluid communication with the exchange region.05-12-2011
20110087188High Flow Volume Nasal Irrigation Device and Method for Alternating Pulsatile and Continuous Fluid Flow - A high flow volume nasal irrigation device for alternating pulsatile and continuous fluid flow includes a tube comprising a free end and a housing at a second end adjoined to a cap with a coaxial cap nipple. A valve assembly inside the housing comprises a disk-like valve and a plurality of housing standoffs configured to stop the valve but allow a fluid flow in the housing and out the nipple. A cylindrical elastic valve seat is adjoined to the cap nipple and forms a gap with the valve on the standoffs. A spring opposes the valve moving toward the valve seat from the standoffs and assists in returning the valve from the seat to the standoffs and thus with the valve seat creates a periodic pulsatile fluid flow in the nipple in response to a chamber pressure which exceeds a critical chamber threshold.04-14-2011
20110087187HYDROPHOBIC DEAERATION MEMBRANE - An optimized deaeration membrane has a biocompatible coating composition. Methods for preparing the membrane and the use of the membrane in medical devices for separating air from liquid that are administered to a living subject, e. g., blood processing devices used in dialysis and the like, are also described.04-14-2011
20090076475METHOD AND APPARATUS FOR DELIVERING THERAPEUTIC OXYGEN TREATMENTS - The present invention provides an applicator for directing a flow of medically pure, therapeutic gas onto a selected portion of the body of a patient. The applicator receives the flow of medically pure, therapeutic gas, such as oxygen, from a source, via a conduit coupled to the source and to the applicator. The applicator can be an adhesive bandage having an inlet for receiving the flow of gas, and one or more outlets for directing the flow of gas. The applicator can also be a mask, patch or similar article configured to be applied to the skin of a patient and connected to a source of medically pure, therapeutic gas via a conduit. The applicator can also having other therapeutic materials impregnated therein. The applicator can also be configured to deliver other therapeutic substances introduced into the flow of gas.03-19-2009
20110213329Modular Fluid Delivery Device with Quick-Release / Connect Mechanism for Drive Screw - Fluid delivery devices and means for engaging components therein are described. The devices may include a plunger positioned within a reservoir and connected to a non-rotating drive screw and a drive nut capable of engagement with the drive screw, where, upon engagement of the drive nut with the drive screw, rotation of the drive nut linearly displaces the drive screw. The devices may also be skin-securable and comprise a reusable part and a disposable part wherein, upon connection of the reusable part and the disposable part, the drive screw engages with the drive nut such that rotation of a motor and/or one or more gears results in rotation of the drive nut and linear displacement of the drive screw.09-01-2011
20100217227METHOD AND APPARATUS FOR DELIVERING OXYGEN AND/OR OTHER GASES AND/OR PHARMACOLOGICAL AGENTS TO TISSUE AND MEDICAL WIRE FOR USE WITHIN THE BODY - A system comprising: a hollow tube having a distal end, a proximal end, and a lumen extending between the distal end and the proximal end; at least a portion of the tube comprising a porous membrane; and a gas-rich perfluorocarbon solution incorporated in the porous membrane; wherein the porous membrane has a porosity in the range of 0.001-200 microns, in order that: (i) the gas-rich perfluorocarbon solution is effectively incorporated into the porous membrane; and (ii) when the porous membrane is positioned in blood, the gas-rich perfluorocarbon solution elutes out of the porous membrane, in aggregations small enough to prevent the creation of embolisms in the blood, with the elution of the gas-rich perfluorocarbon solution into the blood varying between minutes and several hours, depending on the temperature and the hemodynamics of the blood.08-26-2010
20110087186DEVICE FOR ADMINISTERING A FLUID PRODUCT - An administering device for a fluid product includes a product receptacle that accommodates the product to be administered, a fluid reservoir for a driving fluid, a driving means, a product chamber, and a fluid connection. The product receptacle includes an opening at a forward end and a product stopper at a rear end. The driving means acts upon the fluid reservoir, the pressure chamber adjoins the product stopper while the fluid connection is located between the fluid reservoir and the pressure chamber, and the driving means acts upon the fluid reservoir in such a way that the pressure chamber is impinged upon by pressure which affects the product stopper and the product is discharged from the product receptacle.04-14-2011
20110137281Drug delivery device - A drug delivery device mainly has a housing, which can be easily held and operated. The housing has one end formed with an adjustment seat capable of adjusting a range distance, and the other end connected to a gas pressure control source for providing mainstream and substream gas pressures. Disposed in the housing are a drug delivery pressuring tube, an embedded drug-can connecting seat or an external drug-can connecting seat, a replaceable drug-can container and a gas communication tube. According to this design, the minor liquid drug can be controlled, the drug-can can be replaced and the continuous quantitative injection of drug can be made. Also, all damaged or dirty members of the invention may be disassembled, cleaned or replaced.06-09-2011
20110245798Method of Treating Parkinson's Disease in Humans by Convection-Enhanced Infusion of Glial Cell-Line Derived Neurotrophic Factor to the Putamen - A method of treating Parkinson's disease in humans is disclosed, wherein glial cell-line derive neurotrophic factor (GDNF) is chronically administered directly to one or both putamen of a human in need of treatment thereof via convection-enhanced infusion using at least one implantable pump and at least one catheter. In one aspect of the present invention the GDNF is infused directly into one or both putamen through one or more indwelling intraparenchymal mutitiport brain catheters connected to one or moreimplantable pumps wherein the flow rate is pulsed.10-06-2011
20090048574Modular external infusion device - A modular external infusion device that controls the rate a fluid is infused into an individual's body, which includes a first module and a second module. More particularly, the first module may be a pumping module that delivers a fluid, such as a medication, to a patient while the second module may be a programming module that allows a user to select pump flow commands. The second module is removably attachable to the first module.02-19-2009
20100069877APPARATUS AND METHOD TO DISPENSE HPC-BASED VISCOUS LIQUIDS INTO POROUS SUBSTRATES, E.G., CONTINUOUS WEB-BASED PROCESS - Systems and methods are provided for dispensing compositions comprising sols, sol-forming compounds, or highly viscous compositions into porous substrates. In some embodiments, the porous substrates are elements of transdermal delivery devices. In some embodiments, the highly viscous compositions comprise alkylcellulose ethers, or derivatives thereof, in particular, hydroxypropyl cellulose. Such may be useful in continuous web-based manufacturing processes.03-18-2010
20110178497Focused dosimetry device and methods associated therewith07-21-2011
20110178495Internal dry powder delivery system and method thereof - An internal dry powder delivery system through a working channel of an endoscopic cannula for directly applying the powder form medication to an internal tissue/organ site, includes an elongated tubular delivery channel and a powder supply device for producing pressurized gas mixing with the dry powder for feeding to form a mixture of dry powder and pressurized gas delivering to an internal tissue/organ site through the delivery channel via endoscopic cannula. It ensures a smooth powder release by preventing liquid from accumulation at the tip of the delivery channel and offers physicians a new powder form drug delivery method via endoscope. Also, it offers new minimal invasive application by directly and precisely applying the powder format drug to the internal sites of human gastrointestinal organ via endoscope to achieve hemostasis, anti-inflammation, anti-ulcer and anti-tumor treatment, etc.07-21-2011
20100057037Agent Delivery Catheters - An agent delivery catheter that includes an anti-whipping feature, improved assembly of distal parts and/or accuracy/repeatability of needle delivery to a target tissue. Additional features include fitting a catheter with a pneumatic delivery device for delivery of a therapeutic agent without using a needle.03-04-2010
20100057038Device and Method Employing Shape Memory Alloy - A system for the metering and delivery of small discrete volumes of liquid is comprised of a small or minimal number of inexpensive components. One such component is a movable member, such as a miniature precision reciprocating displacement pump head, which is driven by an actuator that comprises a shape memory alloy material. The operating mechanism of the system is of little or minimal complexity. The system facilitates the precise metering and delivery of the small discrete volumes of liquid. Potential applications for the system include subcutaneous, long-term, automated drug delivery, for example, the delivery of insulin to a person with diabetes. In such an application, the small, simple and inexpensive nature of the invention would allow for its use as both a portable and a disposable system.03-04-2010
20110098672BALLOON CATHETER AND METHODS FOR PERICARDIOCENTESIS AND PERCUTANEOUS PERICARDIOTOMY - The present subject matter describes a balloon catheter and methods of using the balloon catheter. The balloon catheter is particularly useful for pericardiocentesis and percutaneous pericardiotomy.04-28-2011
20110152828DOSAGE CONTROL FOR DRUG DELIVERY SYSTEM - A method for delivering intravenous drugs to a patient comprising programming a drug delivery system, including a controller and an infusion pump, with a maintenance rate or a loading dose for a drug and causing the drug delivery system to (a) calculate a loading dose based on the maintenance rate or a maintenance rate based on the loading dose, (b) administer the loading dose of the drug to the patient to rapidly achieve a desired level of effect, and (c) administer the drug at a first maintenance rate to maintain the level of effect.06-23-2011
20110152826Infusion Pump - Infusion pumps according to the present invention maximize fluid throughput while minimizing vaporization of gas by employing specific flow path architecture, flow path dimensional ranges, and voltage and frequency ranges for activation of piezoelectric bodies.06-23-2011
20110152823THROMBUS REMOVAL DEVICE AND SYSTEM - Devices and methods for removing a thrombus (clot) from a vascular structure of a living subject. An embodiment of a thrombus removal device comprises first and second annular members, the first annular member being adapted to slide over a guidewire placed in a vascular structure, the second annular member being coupled to the first annular member and having a suction flow path therethrough, the first annular member having an expandable mesh structure disposed at a distal portion thereof, the mesh structure being deployable to an expanded configuration by movement of an actuating element extending along the second annular member. An embodiment of a thrombus removal method comprises advancing the device to position the mesh structure downstream of the thrombus by sliding the first annular member over the guidewire, applying a suction force to the suction flow path of the second annular member, deploying the mesh structure, and retracting the device to cause the mesh structure to engage the thrombus.06-23-2011
20110251581NEEDLE-LESS INJECTOR AND METHOD OF FLUID DELIVERY - A needle-less injector device for delivering a dose of fluid intradermally, subcutaneously or intramuscularly to an animal or human. The device includes an inner housing having opposed ends. A syringe is disposed in one end of the inner housing. The syringe includes a nozzle for delivering a dose of fluid held within the syringe. A plunger is movably disposed within the syringe. A spring powered hammer is movably disposed within the inner housing. The hammer cooperates with the plunger to drive the dose of medicament from the nozzle. An injection delivery spring for powering the hammer is positioned and compressed between the other end of the inner housing and the spring powered hammer. An outer housing slideably supports the inner housing. A skin tensioning spring is mounted between the inner housing and the outer housing, the skin tensioning spring biasing the nozzle of the syringe against the animal or human. A trigger mechanism is disposed in the outer housing, the trigger mechanism cooperating with the spring powered hammer to release the injection delivery spring, wherein the size of the injection delivery spring and the length of the hammer dictate the amount of dose delivered and whether the dose is delivered intradermally, subcutaneously or intramuscularly to an animal or human.10-13-2011
20110251579SYSTEMS AND METHODS FOR INFUSION OF FLUIDS USING STORED POTENTIAL ENERGY AND A VARIABLE FLOW RESISTOR - Systems and methods for infusion of fluids using stored potential energy and a variable flow resistor. In one aspect of the present disclosure, there is provided an infusion device that includes a plunger situated within a vessel so as to define a chamber within which a volume of fluid can be accommodated between a downstream surface of the plunger and the vessel. The infusion device further includes an outflow path through which the fluid in the chamber can be dispensed upon displacement of the plunger by a force acting thereon. A variable flow resistor is situated within the outflow path and is configured to allow a substantially constant fluid flow rate from the vessel to be maintained as the force acting on the plunger decreases.10-13-2011
20110098673FLUID FLOW CONTROL SYSTEM HAVING CAPILLARY FLUID FLOW RESTRICTOR - A fluid flow rate control system and method comprises a capillary tube having a proximal end that projects into a chamber with a cross-sectional area that is larger than or equal to the fluid supply tube's cross-sectional area. The inner cross-sectional area of the capillary tube is configured less than the inner cross-sectional area of the chamber. The chamber has a volume large enough to slow the fluid conducted to it by the upstream fluid line to permit contaminants to fall out of solution. In another aspect, a sleeve is used to mount the capillary tube into the chamber. The sleeve provides a mounting surface for tube segments from the pump and downstream of the capillary restrictor.04-28-2011
20110098671Over-The-WIre Balloon Catheter for Efficient Targeted Cell Delivery - A method for delivering a therapeutic substance to a treatment site within a body lumen includes advancing a balloon catheter to the treatment site. A balloon of the balloon catheter is inflated and while the balloon is inflated, a primer that coats the treatment site and attracts the therapeutic substance thereto is delivered through a first fluid delivery lumen of the balloon catheter. The balloon of the balloon catheter is deflated for a predetermined period of time. The balloon of the balloon catheter is reinflated and while the balloon is reinflated, the therapeutic substance is delivered through a second fluid delivery lumen of the balloon catheter. The primer improves adherence of the therapeutic substance to the treatment site.04-28-2011
20110082438ANTI-FREE-FLOW MECHANISM FOR ENTERAL FEEDING PUMPS - An anti-free-flow mechanism includes an occluder mechanism which is disposed along a segment of tubing. The occluder mechanism is normally in a biased closed position, but may be moved into an open position by moving an engagement member into engagement with the tubing segment to deform the tubing segment and open a flow channel. Unless force is applied to keep the engagement member in contact with the tubing segment, the tubing will return to the first, closed position.04-07-2011
20110152825PRESSURE MONITORING IN A MODULAR ADMINISTERING DEVICE - An administering device for administering a fluid product through the use of pressure, the device being modular, including a base unit and a cartridge, the base unit containing driving components and the cartridge adapted to be connected detachably to the base unit, wherein the cartridge has a fluid reservoir and a pressure monitoring device having a pressure sensor and a transfer device operably coupled to the pressure sensor, wherein the pressure monitoring device can be activated by an externally applied, alternating electromagnetic field, whereby data can be read, without contact, using the fluid pressure. In one embodiment, the pressure sensor contains a snap disk and the transfer device is an RFID transponder, wherein the base unit comprises a pressure reading device, which is constructed for producing a corresponding alternating electromagnetic field and, depending on the response to the alternating field, for determining a fluid pressure-dependent property of the transfer device.06-23-2011
20110077615Pen Needle Tip - A needle tip assembly includes a needle tip, a needle tip cover structured and arranged to facilitate installation of the needle tip onto at least one of a pen needle, a pre-loaded syringe, and an injection device, and a slot arranged on a sidewall of a body of the needle tip. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way.03-31-2011
20110077614DEVICE AND METHOD FOR PATIENT ACTIVATED BOLUS ADMINISTRATION - A device and method to accept a setting of a maximum volume of a drug that is introduced into a subcutaneous channel upon a patient's direction, while retaining a pre-designated flow of the drug to the channel over an extended period after accounting for such maximum volume.03-31-2011
20110060309Implantable Device for Controlled Drug Delivery - Implantable devices and methods for delivery of lidocaine or other drugs to a patient are provided. In one embodiment, the device includes a first drug portion which has a first drug housing which contains a first drug formulation in a solid form which includes a pharmaceutically acceptable salt of lidocaine; and a second drug portion which includes a second drug housing which contains a second drug formulation which includes lidocaine base. In another embodiment, the device includes a drug reservoir component which has an elastic tube having at least one lumen bounded by a porous sidewall having an open-cell structure, a closed-cell structure, or a combination thereof; and a drug formulation contained within the at least one lumen, wherein the device is deformable between a low-profile deployment shape and a relatively expanded retention shape.03-10-2011
20110251582LOCALIZED DELIVERY OF DRUG AGENTS - Medical devices including a substrate that are expandable from a compressed state to an expanded state; a coating on the substrate, the coating having a drug agent incorporated therein; and a sheath over the coating. The sheath is expandable from a compressed state to an expanded state and has at least one perforation therein. The medical devices are configured such that when the substrate is in a compressed state, the sheath is also in a compressed state and the perforation is substantially closed. When the substrate is in an expanded state, the sheath is also in an expanded state and the perforation is substantially open. The invention also includes a method of using the medical devices for the controlled, localized delivery of a drug agent to a target location within a mammalian body.10-13-2011
20120302989TWO-STAGE RECONSTITUTING INJECTOR - An injector (11-29-2012
20120302988MEDICAL INFUSION PUMP WITH POWER SOURCE VOLTAGE LOGGING AND METHOD FOR LOGGING A POWER SOURCE VOLTAGE IN A MEDICAL INFUSION PUMP - A medical infusion pump and a method for logging a power source voltage of a medical infusion pump are disclosed. The medical pump may include a power source, a processor, and a voltage supervisor which responds if a voltage (VDD) drops to a response voltage level which is above a reset voltage level of the processor. When the voltage supervisor responds, the processor start logging the voltage (Vbat) of the power source in a memory, thus generating a voltage log. The memory maintains the logged data when the power supply by the power source is interrupted, thus enabling retrospective analysis of the voltage log.11-29-2012
20120302987Device, Kit And Method For Closure Of A Body Lumen Puncture - A medical device and method for closure of a puncture in a body lumen are disclosed. The device has an aggregate (11-29-2012
20110257624NEEDLELESS INJECTOR - A needleless injector has a syringe body having an opening at one end, a piston housed within the syringe body for urging a liquid within the syringe body through the opening and a ram for driving the piston. A shock absorbing component is provided for reducing an initial transfer of force from the ram to the piston. The initial rate of pressure increase on the liquid is reduced, thereby controlling the rate of collapse of gas bubbles in the liquid.10-20-2011
20110257622Intravascular Tissue Disruption - Disrupting tissue and devices and systems for disrupting tissue. The disclosure describes ways to deliver moieties to a target tissue, where the target tissue in general is not at the point of introduction, in such a way that minimal damage is produced in the tissue at the point of introduction. In some embodiments this is accomplished by jetting fluid at high velocity into the target tissue. The disclosure further describes novel agents deliverable in such systems for use in remodeling tissues. Some of these agents comprise a liquid while others do not. Additionally, although not specifically described in detail much of the disclosure may additionally be used in the delivery of therapeutic drugs.10-20-2011
20110251578Sub-mucosal agent delivery apparatus,system and method - An agent delivery apparatus for administering a pharmacological agent formulation to a sub-mucosal compartment of a body organ, comprising injector means having an internal formulation chamber that is adapted to receive and contain the pharmacological agent formulation therein and an elongated agent delivery member having a first end that is in communication with the internal formulation chamber and a delivery nozzle end, the injector means including force generating means that is adapted to generate sufficient force to expel the pharmacological agent formulation from the injector means and into and through the agent delivery member, and out of the delivery nozzle end of the elongated agent delivery member with a delivery pressure in the range of approximately 10-13-2011
20110178496METHOD OF PREVENTING INADVERTENT INTERCONNECTION IN MEDICAL SYSTEMS USING ADAPTER - A method of preventing inadvertent interconnection between a first medical system and a second medical system utilizes a luer fitting connector/adapter that acts as a modified-to-standard size converter piece. The adapter may complete a fluid tight medical system. The adapter may have one end having at least one non-standard sized luer fitting dimension. The non-standard end of the adapter may sealingly interconnect with a luer fitting member having a corresponding non-standard sized dimension. As a result, the adapter and luer fitting member may be directly interconnected with one another while remaining incompatible with standard sized luer fittings. Using the adapter may facilitate preventing the inadvertent direct interconnection of standard sized luer fitting members intended for different purposes, such as the delivery of a feed paste or a medication to a desired location within a patient. The adapter may be directly or indirectly interconnected with a syringe nozzle to facilitate flushing the medical system or a portion thereof.07-21-2011
20120123384Dispensing Fluid from an Infusion Pump System - Some embodiments of a medical infusion pump system include a pump device having a flexible pushrod that can adjust from a curved configuration to a generally straight configuration. The flexible pushrod is part of a drive system of the pump device so that the flexible pushrod can be controllably and incrementally advanced toward a medicine reservoir to incrementally dispense the medicine therein. In particular embodiments, the flexible pushrod may comprise an anti-rotation mechanism, an anti-torsion mechanism, or a combination thereof.05-17-2012
20110046600DEVICES, SYSTEMS, AND RELATED METHODS FOR DELIVERY OF FLUID TO TISSUE - Described are devices useful to inject fluid to tissue without the use of a needle, and related methods; the devices include one or a combination of features such as ejection orifices, distal end control features, or combinations of these; the systems can include a fluid delivery system having an injector source and an access device; the access device can comprise a minimally invasive, tubular delivery lumen such as a catheter or endoscope; the tube-like device further includes one or more apposing jets that are selectively fired to force the injection orifice of the tube-like device against the target tissue; selective firing can include a continuous firing during the injection to improve the efficiency of the treatment.02-24-2011
20120277717LIMITING PRESSURE IN AN IMPLANTED CATHETER - A method includes receiving data regarding a catheter being used with the infusion device. The catheter has a lumen operably coupled to a reservoir of the infusion device and is configured to deliver fluid from the infusion device to a target location of a patient. The method further includes infusing fluid from the reservoir into the lumen of the catheter at a first rate and monitoring pressure via a pressure sensor in communication with the lumen of the catheter. Monitoring the pressure includes acquiring pressure data from the pressure sensor at a first frequency. The method also includes (i) determining whether the monitored pressure exceeds a first threshold, wherein the first threshold is based on the data regarding the catheter; and (ii) decreasing the rate at which the fluid is delivered from the reservoir into the catheter if the monitored pressure is determined to exceed the threshold.11-01-2012
20090312742DRUG-DELIVERY PUMPS AND METHODS OF MANUFACTURE - Embodiments of an implantable electrolytic pump include a first expandable diaphragm and a second flexible diaphragm, and first and second chambers each for containing a fluid, wherein the first expandable diaphragm separates the first and second chambers and provides a fluid barrier therebetween, and the second chamber is formed between the first expandable diaphragm and the second flexible diaphragms. The pump may further include electrolysis electrodes within the first chamber for causing generation of a gas therein and to thereby expand the expandable diaphragm so that fluid is forced from the second chamber into a cannula.12-17-2009
20120203195SYRINGE PUMP RAPID OCCLUSION DETECTION SYSTEM - An apparatus, method and program product detects an occlusion in a fluid line by determining if a relationship between force measurements departs from an expected relationship.08-09-2012
20110152824INFUSION PUMP SYSTEM WITH DISPOSABLE CARTRIDGE HAVING PRESSURE VENTING AND PRESSURE FEEDBACK - Embodiments are directed to portable infusion devices, systems, and methods of using the same for dispensing materials. In some cases, the devices, systems and methods may be used for infusing a material such as medicament, e.g., insulin, into a body in need thereof.06-23-2011
20090143759Methods, Devices, Kits and Systems for Defunctionalizing the Cystic Duct - The application discloses devices, systems, kits and methods for treating biliary disease. Devices comprise, for example, a component configurable for deployment between within a cystic duct of a patient which has a proximal end and a distal end. In some embodiments, a lumen may also extend therethrough.06-04-2009
20090143760Methods, Devices, Kits and Systems for Defunctionalizing the Gallbladder - The application discloses devices, systems, kits and methods for treating biliary disease. Device comprise, for example, a component configured for deployment to a lumen of a gallbladder or gallbladder duct which has a proximal end and a distal end with a lumen extending therethrough and a fluid or gas delivery apparatus at its distal end.06-04-2009
20110213328Methods and Systems for Treatment of Neurological Diseases of the Central Nervous System - The present invention is directed to methods and systems for the treatment of inborn genetic errors or other defects that cause deficiencies of active enzymes or proteins within the cells of the central nervous system. Such methods and systems generally comprise an implantable catheter system designed for the chronic delivery of specially formulated proteins to intrathecal, intracerebroventricular, and/or intraparenchymal regions of the central nervous system. The invention has application in the neuropathic aspects of the broad category of lysosomal storage diseases. These genetic based diseases are the result of insufficient enzyme activity to catabolize specific substances, which thereby accumulate in the cellular lysosomes.09-01-2011
20110257623IMPLANTABLE MEDICAL DEVICES HAVING MICROPOROUS SURFACE LAYERS AND METHOD FOR REDUCING FOREIGN BODY RESPONSE TO THE SAME - This disclosure provides implantable devices coated with microporous surface layers with macrotopographic features that improve bio-integration at the interface of the implantable devices and the surrounding tissue.10-20-2011
20110257625INFUSION SYSTEM PROGRAMMABLE IN FLEX MODE - A drug infusion system capable of delivering a fluid medication to a patient under direction of a medical professional continually at a basal rate and at an interval rate in each of a plurality of time slots over a specified period of time. The total dose of the fluid medication to be delivered to the patient over the period of time based on the basal rate and the interval rate for each of the plurality of time slots is determined, compared the total dose against a maximum dose. The basal rate is adjusted, if necessary, so that the total dose does not exceed the maximum dose.10-20-2011
20120277716DETECTING AND RESPONDING TO SOFTWARE AND HARDWARE ANOMALIES IN A FLUID DELIVERY SYSTEM - A total dose of a therapeutic agent to be delivered to a patient by an infusion device over a total period of time is automatically divided into a plurality of unit doses to be delivered to the patient over a plurality of unit periods of time. The infusion device is automatically programmed to deliver one of the unit doses of the therapeutic agent to the patient over its respective unit period of time, after which the one unit dose is delivered, and a determination is made of whether an error occurred in delivering the one unit dose to the patient. Delivery of the total dose of the therapeutic agent to the patient may include iteratively automatically programming the infusion device to deliver successive unit doses upon determining that no error occurred in delivering a previous unit dose to the patient. Accordingly, the risk of improperly dosing the patient with the therapeutic agent in an event of a software or hardware anomaly within the infusion device is prevented or reduced.11-01-2012
20110054438STENT DELIVERY AT A BIFURCATION, SYSTEMS AND METHODS - The present invention provides systems and methods for delivery of a stent or scaffold at a blood vessel or body lumen bifurcation. A method can include positioning a scaffold at a bifurcation of a main lumen into first and second branch lumens using a first expansion catheter, inflating a main balloon of the catheter to expand the proximal portion of the scaffold, positioning a second expansion system, and expanding the distal portion of the scaffold on a generally distal side of the bifurcation.03-03-2011
20110082439Portable Infusion Pump and Media Player - Some embodiments of a portable infusion pump system can be configured to deliver medicine (e.g., insulin or the like) to a user and to deliver media content to a user. The media content can include, for example, MP3 music and other audio/video data stored in a memory device in the portable system. Thus, in particular embodiments, the portable infusion pump system can serve a dual purpose of providing medication and entertainment for the user from a compact and unobtrusive device.04-07-2011
20100292668METHOD AND APPARATUS FOR DELIVERY OF A THERAPEUTIC AGENT WITH AN EXPANDABLE MEDICAL DEVICE - Described herein is a medical device that has a collapsed configuration and an expanded configuration wherein one or more polymeric network layers are applied to the substrate and microparticles embedded in the polymeric network. The polymeric network layer or layers is/are configured to retain the microparticles when the device is in a collapsed configuration and to release the microparticles when the device is in an expanded configuration. Methods for delivering a therapeutic agent using the device and making the device are also disclosed.11-18-2010
20110118694Device, A System and a Method for Identification/Authentication of Parts of a Medical Device - Disclosed is a dispensing system. The dispensing system includes a dispensing unit to dispense therapeutic fluid, and a validation mechanism to enable operation of the dispensing unit based, at least in part, on a determination of whether operation of the dispensing device is authorized.05-19-2011
20110125129Medical device with adjustable tissue ingrowth cuff - Methods and apparatus are disclosed for making and using adjustable epidermal tissue ingrowth cuff and catheter assemblies for transcutaneous placement to provide periodic or continuous external access for medical purposes to an interior body region of a patent who requires such medical treatment over an extended period of time.05-26-2011
20120150143Infusion monitoring device, system and method - A system for automatically monitoring an infusion in a patient receiving an infusion from a fluid source, the system including: an infusion monitoring device comprising: a fluid valve, disposed in a fluid connection between the fluid source and the patient, and operable for preventing or allowing the flow of fluid from the fluid source to the patient; a variable volume chamber, fluidly coupled between the fluid valve and the patient, for allowing the creation of a pressure differential between the variable volume chamber and the patient; and a fluid inspection window, disposed in the fluid connection between the variable volume chamber and the patient, for allowing a view of fluid drawn from the patient into the infusion monitoring device when the fluid valve is closed and the variable volume chamber creates a negative pressure differential between the variable volume chamber and the patient.06-14-2012
20100324527DRUG DELIVERY DOSE SETTING MECHANISM WITH VARIABLE MAXIMUM DOSE - A method and system for proving a drug delivery device having a variable dose. The drug delivery device comprising a first tubular member and a second tubular member rotatably coupled to the first tubular member. A maximum stop component is operatively coupled to the first and second tubular member such that the maximum stop component is movable from a first position to a second position. The first position defines a first maximum dose that may be set by a user of said drug delivery device and the second position defines a second maximum dose that may be set by the user of said drug delivery device.12-23-2010
20100179507Syringe and method of use - A syringe and a method of using the syringe are disclosed. The syringe includes a longitudinal body having proximal and distal ends and including an aperture between the proximal and distal ends. An injectable material, such as an adhesive bone cement, may be loaded into the body of the syringe through the aperture. After the injectable material is inserted, the aperture may be closed by covering the aperture with an aperture cover. The aperture cover may be configured to slide into a position covering the aperture, or the aperture cover may be placed in a position covering the aperture, such as by pivoting about a hinge. After the aperture is closed, the injectable material may be dispensed from the distal end of the syringe body by depressing a plunger. Depressing the plunger may initiate the closing of the aperture, or the aperture may be closed independently of plunger movement.07-15-2010
20090171312System And Method For Remotely Operating A Peristaltic Pump - A method of storing on a remote storage device protocol information for a drug for administration via a peristaltic pump is disclosed. A communications path between the peristaltic pump and the remote storage device is provided. The protocol information for the drug is entered into the peristaltic pump. The protocol information is transferred from the peristaltic pump to the remote storage device. The protocol information for the drug is stored on the remote storage device. History information may be retrieved from the peristaltic pump. A user request is received requesting retrieval of history information from the peristaltic pump. A pump request is formatted to retrieve history information. The pump request to receive history information is transmitted to the peristaltic pump. The history information is received from the peristaltic pump. The history information is displayed and stored.07-02-2009
20110137283PROCESS FOR OBTAINING HIGH EFFICIENCY HUMAN ALBUMIN FOR USE IN DETOXIFICATION THERAPY - A process for purifying and collecting albumin from plasma and plasma fractions involves diafiltration of an albumin-containing plasma fraction; stabilizing the resulting albumin fraction with sodium chloride and an amino acid in the absence of any added fatty acid; pasteurizing the stabilized albumin fraction; and diafiltering the pasteurized fraction to remove, along other things, stabilizers. In one embodiment, the amino acid stabilizing agent is acetyl tryptophan. The resulting albumin has at least about 80% albumin binding capacity relative to natural plasma albumin, and is storage stable for about 30 months at 30° C.06-09-2011
20110137282METHOD AND APPARATUS FOR CURVING A CATHETER - An apparatus and method for curving a catheter after deployment include a catheter having a primary lumen, a secondary lumen, and a resilient fiber contained within the secondary lumen. The resilient fiber and the secondary lumen have corresponding, preformed curve shapes when the catheter is in a straight, unstressed condition. The resilient fiber is slidable within the secondary lumen to create a desired curve shape in the catheter as the curved portion of the resilient fiber slides into an originally straight portion of the secondary lumen. In another embodiment, the preformed curve shape of the resilient fiber is held in a straight condition within a stiff, marker ring segment of the catheter until after the catheter is deployed. Once deployed, the resilient fiber is slid out of the marker ring segment, and the preformed curve shape of the resilient fiber creates a corresponding curve shape in the catheter.06-09-2011
20100198188Devices and Methods for Metering Insoluble Active Agent Particles - Embodiments of the present disclosure relate to devices for delivering a predetermined amount of an active agent to a subject by inclusion of a detector configured to detect the number of insoluble active agent particles in a fluid flowing by the detector. A controller is operably connected to the detector and configured to determine the amount of the active agent to be delivered to the subject based on the number of insoluble active agent particles flowing by the detector. Also provided are methods of using the subject devices for delivering a predetermined amount of an active agent to a subject.08-05-2010
20110184378TREATMENT INSTRUMENT AND TREATMENT METHOD - A procedure of positioning a treatment part at various sites on an organ is facilitated, and the positioning thereof can be stably maintained for treatment with accurate positioning. A treatment instrument includes a rigid rod-shaped insertion section having a treatment part at a distal end thereof and a manipulating section secured to a proximal end of the insertion section and gripped and manipulated by an operator. The insertion section includes a main body extending in a straight line, a first curved portion disposed at a distal end of the main body and curved in one direction with respect to the main body, and a second curved portion disposed on a distal side of the first curved portion and curved in a direction opposite to the direction in which the first curved portion is curved. The treatment part is inclined with respect to the longitudinal axis of the main body.07-28-2011
20120209239PATCH-SIZED FLUID DELIVERY SYSTEMS AND METHODS - A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.08-16-2012
20120150142Drug Eluting Balloons with Ability for Double Treatment - In embodiments, medical devices, such as balloon catheters, can deliver a biologically active material to body tissue of a patient. The medical device includes a sponge delivery layer which can deliver multiple doses of one or more therapeutic agents to the body tissue. The medical device can further include a drug reservoir, which can supply the delivery layer with one or more therapeutic agents.06-14-2012
20100191214MORE EASILY USABLE ADMINISTERING APPARATUS - An administering device for liquid medicine including a basal rate selection switch for adjusting a basal rate, a bolus button encompassing an adjusting wheel for adjusting a bolus dose, and a trigger button for triggering administering of said dose, wherein the trigger button is centrally disposed in the adjusting wheel and the bolus button is arranged at an angle on the housing to make it easier to manipulate it, and wherein, to increase operational safety, a bolus is administered only when a specific sequence of states of the bolus button have been achieved and/or followed. In some embodiments, the bolus button may be additionally used for acknowledging alerts and/or, in some embodiments, a pillow-type, cushioning cover allows the device to be comfortably used also when sleeping. The invention encompasses a method of using an administering device, wherein during operation of the device, a basal rate selection switch is covered by a locking mechanism which locks a cartridge and an adapter for a catheter on a base unit.07-29-2010
20110264070DEVICE FOR INFUSION OF PRESCRIPTION MEDICINES OR TREATMENTS - An infusion assembly is provided having a first outlet conduit adapted to be in fluid communication with a delivery site of a patient. The assembly further includes at least first and second fluid inlet conduits adapted to be in fluid communication with at least a first and second fluid reservoir, and an infusion switching device, including a housing and an internal valve assembly. The internal valve assembly is adapted for selective manipulation by a patient or caregiver. The valve assembly includes an off-setting, and first infusion setting, for initiating an infusion of a first fluid from a first fluid reservoir to a delivery site, and a second infusion setting for initiating an infusion of a second fluid from a second fluid reservoir to a delivery site.10-27-2011
20110152827DRUG DELIVERY PUMP DRIVE USING LINEAR PIEZOELECTRIC MOTOR - A drug delivery pump drive which uses a linear piezoelectric motor to advance a syringe piston to deliver a liquid drug and a method thereof are disclosed. The pump drive, provided in a drug delivery pump, provides silent operation and very low energy consumption compared to electric motor-based drives. The small size of the motor helps also to reduce overall size of the pump drive and the resulting drug deliver pump.06-23-2011
20100030183Method of treating vascular disease at a bifurcated vessel using a coated balloon - Disclosed is a method for delivery of at least one therapeutic agent from an angioplasty balloon for treating vascular disease at a bifurcated vessel. The invention also relates to the method of loading the beneficial agents onto the balloon and the device, as well as the method of delivery of the agents from separate surfaces. The invention also relates to a method of loading multiple beneficial agents onto the balloon surfaces02-04-2010
20100030184SPINAL PLATFORM AND METHOD FOR DELIVERING A THERAPEUTIC AGENT TO A SPINAL CORD TARGET - A spinal platform for delivering a therapeutic agent to a spinal cord target includes a brace member for attachment to a plurality of bony structures surrounding at least a portion of the spinal cord target, a carriage member operatively coupled to and movable along the brace member, and a universal joint for adjusting the coronal or sagittal angle of a surgical instrument. The brace member includes at least one longitudinal rail and a plurality of attachment members. The plurality of attachment members is operably connected to the at least one longitudinal rail. The at least one longitudinal rail includes a proximal end portion, a distal end portion, and a middle portion extending between the proximal and distal end portions. The universal joint is seated within a portion of the carriage member and is capable of delivering the therapeutic agent to the spinal cord target.02-04-2010
20100022987MEDICATION DELIVERY SYSTEM - A medication delivery system includes an array of cartridge-receiving ports, a medication receiving fluid conduit, and a plurality of dispensing elements. Each port includes a fluid channel terminating at a fluid outlet and is configured to receive one of a plurality of cartridges that each contain a bolus volume of medication. The medication-receiving fluid conduit is fluidically coupled to the fluid outlet of each cartridge-receiving port at a first region and to a system outlet conduit at a second region (which in turn can be coupled to a patient catheter line). Each dispensing element corresponds to a single cartridge-receiving port so that, upon activation of the dispensing element, at least a portion of the bolus volume of medication flows through the fluid outlet of each cartridge-receiving port into the medication-receiving fluid conduit. Related apparatus, systems, and methods are also disclosed.01-28-2010
20120150141DIALYSIS MACHINE, A MANIFOLD FOR THE DIALYSIS MACHINE AND PROCESS - The present invention relates to a dialysis machine for the purification of blood, a manifold for the dialysis machine as well as to a process for the regeneration of the dialysis bath. It is an object of the present invention to provide a dialysis machine, a manifold for the dialysis machine as well a process which facilitates the administration of medical preparations during a dialysis procedure. In order to solve the object, a dialysis machine according to the present invention comprises tubes (06-14-2012
20110218515Methods for Treating Acute Myocardial Infarctions and Associated Disorders - The invention relates to methods of treating patients who have suffered an acute myocardial infarction (AMI) with a therapeutic that has anti-fibrotic effects, for example, pirfenidone and analogs thereof.09-08-2011
20110218516Methods and Devices for Programmable Delivery of Microdoses of Liquid Drugs - Devices of this invention include replaceable cartridges for delivery of doses of fluids. Cartridges having a fluid supply reservoir comprising an expandable element are designed to be connected with non-disposable actuating module supplied with a sensor, a mechanism to apply a force to the fluid, thereby forcing a predetermined dose out of the reservoir, and a processor providing control outputs from a sensor system according to preprogrammed instructions. Methods of this invention include delivery of microdoses of fluids using devices of this invention.09-08-2011
20110218514AUTOMATIC RELAY PUMP SYSTEM AND METHOD - An automatic pump relay system includes controllers coupled to drivers for sequentially discharging fluid from a plurality of medication containers into a coupler having a reflux barrier from which fluid is administered to a patient. The internal fluid pressure of the coupler is determined by a pressure sensing device or devices that provide signals to the controllers that, based at least on the sensor signals, cause the drivers to operate in reverse and forward directions so as to rapidly decrease and raise the fluid pressure within the coupler during a relay from an empty syringe to a filled syringe, thereby avoiding bolus formation and an interruption in infusion therapy. Independently operable syringes pumps are contemplated to be connected in relay fashion to form a modular system. An associated method is also disclosed wherein a fluid administration pressure is stored for use as a reference during a syringe changeover.09-08-2011
20110218513Biologics Delivery System - A system for harvesting, preparing, and delivering biological materials or other therapeutic agents is disclosed. The system is adaptable to a variety of biological materials or other therapeutic agents. The system is adaptable for minimally invasive procedures where access may be limited. The system includes provisions for delivering biological materials or other therapeutic agents along a curved path. The system is adaptable to maximize the delivered quantity of biological materials or other therapeutic agents, thus minimizing waste.09-08-2011
20110218512ENHANCED ANTIVIRAL THERAPY METHODS AND DEVICES - Embodiments of the present invention relate to enhanced antiviral therapy methods, devices, and kits for treating viral infections. The disclosed enhanced antiviral therapy methods, devices, and kits enhance the efficacy of an antiviral therapy by administering a lectin affinity hemodialysis treatment to an individual suffering from viral infection in combination with the antiviral therapy.09-08-2011
20100016827NEEDLE-FREE INJECTOR DEVICE WITH AUTOLOADING CAPABILITY - A needle-free transdermal transport device includes a chamber (01-21-2010
20130012916DELIVERY OF IMMUNOGLOBULIN VARIABLE DOMAINS AND CONSTRUCTS THEREOF - The present invention relates to formulations and methods for administering therapeutic molecules comprising immunoglobulin variable domains using needle-free delivery devices.01-10-2013
20130012917Power Management Techniques for an Infusion Pump System - Some embodiments of an infusion pump system can employ a number of power management techniques to avoid using substantially excessive power during operation of the pump drive system. Thus, the infusion pump system can draw upon the energy supply in an efficient manner that extends the useful life on the power supply. Furthermore, the infusion pump system can be configured estimate an amount of power remaining to operate the pump system without the requirement of directly detecting the remaining charge on power supply device (e.g., without detecting the remaining charge on a battery). As such, the infusion pump system can readily inform a user of a particular estimated amount of time remaining for medicine dispensing operations.01-10-2013
20130012913INJECTABLE CROSS-LINKED HYDROGELS FOR BIOMATERIAL APPLICATIONS - An injectable hydrogel composition comprising: water; and poly(vinyl alcohol) chemically cross-linked with a second polymer to form a cross-linked resin, wherein the second polymer is selected from the group consisting of: a polyhydric alcohol compound, a polyvalent epoxy compound, a polyvalent amine compound, a dialdehyde compound, a diisocyanate compound, and mixtures thereof, wherein the cross-linked resin has a degree of cross-linking of from about 0.0001 mol/mL to about 0.002 mol/mL, and wherein the hydrogel is flowable when heated above its melting point.01-10-2013
20130012914WASTE BALANCING FOR EXTRACORPOREAL BLOOD TREATMENT SYSTEMS - One or more waste balancing systems may be used in a fluid circulating system for medical use. The fluid circulating system may be part of a blood treatment system for a patient suffering renal failure. A waste balancing system may include a pressure element operable to maintain a constant fluid pressure created by the combined weight of waste removed from a patient and replacement fluid for providing to a patient. Multiple evaluation characteristics or control parameters may be evaluated or controlled for safety and accuracy. At least part of the waste balancing system may be incorporated into a disposable cartridge.01-10-2013
20090118695MEDICAL DEVICE FOR ADMINISTERING A SOLUTION - Medical device for administering a solution, said device comprising pumping means, a reservoir, means of communication between said reservoir and said pumping means, and a line for connecting the medical device to a patient, characterized in that it comprises means for determining the physical/chemical characteristics of the solution as a function of time by means of a mathematical model that takes account of the permeability of the reservoir walls as a function of time and the temperature of the solution.05-07-2009
20100262115NANOPARTICLES FOR CANCER SONODYNAMIC AND PHOTODYNAMIC THERAPY - The present invention is directed to nanoparticles comprising a cancer therapeutic, pharmaceutical compositions comprising same, and methods for using same for drug delivery and ultrasound or light-based treatment of cancer.10-14-2010
20120041412BIODEGRADABLE PROTRUSIONS ON INFLATABLE DEVICE - A medical device for insertion and expansion in a body passageway. The medical device includes an inflatable device such as a balloon that is designed to be inflated and deflated while positioned in the body passageway. The inflatable device is inflatable by inserting a fluid in an internal cavity of the inflatable device. The inflatable device includes an outer surface that has a surface structure or micro-surface structure which is designed to at least partially penetrate into an inner wall of the body passageway when the inflatable device is inflated.02-16-2012
20120041415MEDICATION DELIVERY SYSTEM AND MONITOR - Systems and methods for the delivery and monitoring of a medication, such as insulin, to a recipient are provided. An exemplary feature-rich system comprises an infusion pump with a control system for controlling medication delivery by the infusion pump and a bolus estimator for estimating an appropriate amount of medication for delivery by the control system with the infusion pump. Estimating the appropriate amount of medication for delivery is based upon one or more settings which each vary according to a setting profile. In other embodiments, the control system comprises a suspend function for temporarily suspending medication delivery by the infusion pump, an alarm profile function for programming a variable alarm volume of the alarm and a simplified menu for controlling the dual wave bolus delivery function.02-16-2012
20110112502NEEDLELESS DEVICE FOR DELIVERY OF AN AGENT THROUGH A BIOLOGICAL BARRIER - A needleless device (05-12-2011
20120041414MEDICATION DELIVERY SYSTEM AND MONITOR - Systems and methods for the delivery and monitoring of a medication, such as insulin, to a recipient are provided. An exemplary feature-rich system comprises an infusion pump with a control system for controlling medication delivery by the infusion pump and a bolus estimator for estimating an appropriate amount of medication for delivery by the control system with the infusion pump. Estimating the appropriate amount of medication for delivery is based upon one or more settings which each vary according to a setting profile. In other embodiments, the control system comprises a suspend function for temporarily suspending medication delivery by the infusion pump, an alarm profile function for programming a variable alarm volume of the alarm and a simplified menu for controlling the dual wave bolus delivery function.02-16-2012
20120041413PORTABLE INFUSION MANAGEMENT APPARATUS AND METHOD - A portable infusion apparatus and method are provided for controlling the delivery of medicinal fluid to a patient.02-16-2012
20120041411LOW PROFILE GUIDING CATHETER FOR NEUROVASCULAR APPLICATIONS - A low profile guiding catheter has a non-round shape for use in delivery of multiple microcatheters for treatment of neurovascular defects, such as for treatment of aneurysms. The low profile guiding catheter includes torque transmittal guidance walls that are flexible linearly but not circumferentially, and that are neither collapsible nor kinkable.02-16-2012
20130197469APPARATUS, SYSTEM AND METHOD FOR ADMINISTRATION OF A SUBSTANCE - The present disclosure relates to an infusion control valve adapted to be actuated by a valve actuator. The present disclosure further relates to an infusion valve actuator adapted to actuate an infusion control valve upon being triggered by an authentication unit. Furthermore, the present disclosure relates to methods for the administration of a substance.08-01-2013
20090312740Balloon Inflation Device - One embodiment provides a method implemented by a powered inflation device to prepare a balloon catheter for use during a medical procedure. In this embodiment, the method includes drawing an amount of medical fluid from a fluid reservoir into the inflation device during a first motorized operation of the inflation device, removing an amount of air from the balloon catheter during a second motorized operation of the inflation device, and injecting the amount of medical fluid from the inflation device into the balloon catheter during a third motorized operation of the inflation device to inflate a balloon located at a distal end of the balloon catheter The powered inflation device may be a stand-alone device in one embodiment. In one embodiment, the powered inflation device is coupled to an angiographic injector system. When it is coupled to an angiographic injector system, the balloon inflation device and the injector system may be controlled by a common control panel, or console, in one embodiment.12-17-2009
20120046640Coating Comprising An Elastin-Based Copolymer - The present invention is directed to medical devices including coatings. The coatings include a topcoat which includes a copolymer comprising a block of an elastin pentapeptide. The topcoat is over a layer of poly(vinyl alcohol) on a hydrophobic coating or over a porous coating comprising pores or depots that include a bioactive agent.02-23-2012
20120046638Method of inducing a CTL response - Disclosed herein are methods for inducing an immunological CTL response to an antigen by sustained, regular delivery of the antigen to a mammal so that the antigen reaches the lymphatic system. Antigen is delivered at a level sufficient to induce an immunologic CTL response in a mammal and the level of the antigen in the mammal's lymphatic system is maintained over time sufficient to maintain the immunologic CTL response. Also disclosed is an article of manufacture for delivering an antigen that induces a CTL response in an animal.02-23-2012
20120004636HEMOSTATIC FIBROUS MATERIAL - This disclosure relates to devices for promoting the clotting of blood in human beings or animals, or hemostatic devices. These devices may comprise a fibrous material or materials comprising one or more fibers such as a gauze or a cloth. Some of the fibers in these materials or devices may comprise a macromolecular material and a hemostatic hemostatic additive material such as kaolin or another clay.01-05-2012
20120310204Method and System for Alerting as to Potential for Bolus Condition - A method of alerting a user to a potential unintended bolus delivery includes delivering fluid to a patient along a first fluid flow path. The method also includes transmitting a signal prior to initiation of a change in fluid delivery to the patient along a second fluid flow path connected to the first fluid flow path upstream of the patient, and detecting the signal. The method further includes actuating an alarm to alert the user to a potential unintended bolus delivery if the signal is detected. A system for carrying out the method is also provided.12-06-2012
20120209240PATCH-SIZED FLUID DELIVERY SYSTEMS AND METHODS - A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.08-16-2012
20120209241MEDICAL FLUID DELIVERY DEVICE PROGRAMMING - In some aspects, systems, devices, and techniques for programming a medical fluid delivery device are described. In one example, the disclosure relates to a system including a medical fluid delivery device configured to deliver a therapeutic agent to a patient, and a processor. The processor may be configured to receive a proposed therapy dosing program that defines a fluid therapy for delivery to a patient via a medical fluid delivery device for a first period of time, determine a total dosage over a second period of time, where the second period of time at least partially overlaps the first period of time, and compare the total dosage over the second period of time to a reference dosage.08-16-2012
20120010589LOCAL DELIVERY OF THERAPEUTIC AGENT TO HEART VALVES - The present invention relates to implantable medical devices and methods that employ these medical devices to treat heart valves. In one embodiment, a medical device is provided comprising a body. The body may have a portion thereof including therapeutic agent and can be configured to support the device proximate a heart valve. Methods in accordance with embodiments of the present invention may also include providing a medical device having a body with at least a portion thereof including a therapeutic agent. These methods may also include positioning the medical device in a location proximate to a downstream surface of the heart valve and securing the device. The therapeutic agent released may then be delivered to the heart valve.01-12-2012
20110166546METHODS AND SYSTEMS FOR STIMULATING A MOTOR CORTEX OF THE BRAIN TO TREAT A MEDICAL CONDITION - Methods of treating a medical condition include applying at least one stimulus to a motor cortex within a brain of a patient with an implanted system control unit in accordance with one or more stimulation parameters. Systems for treating a medical condition include a system control unit implanted within the patient that is configured to apply at least one stimulus to a motor cortex within a brain of a patient in accordance with one or more stimulation parameters.07-07-2011
20110166544INFUSION PUMP SYSTEM WITH DISPOSABLE CARTRIDGE HAVING PRESSURE VENTING AND PRESSURE FEEDBACK - Embodiments are directed to portable infusion devices, systems, and methods of using the same for dispensing materials. In some cases, the devices, systems and methods may be used for infusing a material such as medicament, e.g., insulin, into a body in need thereof.07-07-2011
20110166545APOPTOSIS-INDUCING AGENT FOR PROSTATE CANCER CELLS - According to the present invention, an apoptosis-inducing agent for prostate cancer comprising REIC/Dkk-3 DNA or an REIC/Dkk-3 protein, and a therapeutic agent for prostate cancer and an agent for inhibiting prostate cancer metastasis that comprise such apoptosis-inducing agent are provided.07-07-2011
20120016336TREATMENT OF MOOD AND/OR ANXIETY DISORDERS BY ELECTRICAL BRAIN STIMULATION AND/OR DRUG INFUSION - A system and method for introducing one or more stimulating drugs and/or applying electrical stimulation to the brain to treat mood and/or anxiety disorders uses an implantable system control unit (SCU), specifically an implantable signal/pulse generator (IPG) or microstimulator with one or more electrodes in the case of electrical stimulation, and an implantable pump with one or more catheters in the case of drug infusion. In cases requiring both electrical and drug stimulation, one or more SCUs are used. Alternatively and preferably, when needed, an SCU provides both electrical stimulation and one or more stimulating drugs. In a preferred embodiment, the system is capable of open- and closed-loop operation. In closed-loop operation, at least one SCU includes a sensor, and the sensed condition is used to adjust stimulation parameters.01-19-2012
20120016335METHOD AND SYSTEM FOR TREATING BLADDER CONDITIONS - A method of treating a bladder condition is provided. The method is effected by circulating a volume of heated fluid through a urinary bladder of a subject in need and gradually increasing the volume of fluid up to a predetermined fluid volume and or pressure.01-19-2012
20120209242METHOD FOR ALLEVIATING CONDITION OF SPINAL CANAL STENOSIS BY LOCAL ADMINISTRATION OF MEDICINE - Disclosed herein is a method for alleviating the condition of spinal canal stenosis, including: transluminally placing a catheter in a lumbar artery, iliolumbar artery or lateral sacral artery at the proximity of a narrowed area of a spinal canal; and injecting a vasodilator into the artery via the catheter.08-16-2012
20120022496Dispensing Fluid from an Infusion Pump System - Some embodiments of a medical infusion pump system include a pump device having a cap device that mates with a pump housing to retain a medicine cartridge therein. In addition to retaining the medicine cartridge in the pump housing, the cap device may perform a number of preparatory functions or safety functions. In addition or in the alternative, some embodiments of the pump device may include a drive system that advances a piston rod to dispense medicine to the patient in a safe and energy efficient manner.01-26-2012
20120022495Molds For In Situ Forming Materials - An applicator for use in tissue repair is provided. The applicator includes a base configured to dispense a material and an applicator tip operably connected to the base. The applicator tip includes a body having a distal end configured to engage a tissue defect and a mold disposed about the body configured to engage tissue about the tissue defect. The mold is configured to be selectively positioned about the distal end of the body between at least a first position and a second position to deposit material to form at least a first layer and a second layer. Also provided are applicator tips, methods and kits for tissue repair.01-26-2012
20120022494MATRIX INFUSION PUMP AND DISPOSABLE SET - A matrix infusion cassette for use with an intravenous (IV) pump is disclosed. The matrix infusion cassette includes a body configured to attach to the IV pump, the body having one or more inlet ports, an outlet port, and a plurality of pumping chambers, and a plurality of fluid conduits connecting the inlet ports to at least one pumping chamber, interconnecting the pumping chambers, and connecting at least one pumping chamber to the outlet port.01-26-2012
20120059349IMPLANTABLE DRUG DELIVERY DEVICES - The invention relates generally to implantable drug delivery devices. Devices having a single drug chamber configuration, a divided drug chamber configuration and a compact dual-drug configuration are described. The devices have features to prevent clogging of the dispensing catheter and the creation of a local vacuum caused by the dispensing of the drug fluid. Also provided are features of a failsafe refilling process, automatic refill notification, and performance verification process. The divided drug chamber configuration enables frequent or continuous minute doses. A dual-drug chamber configuration uses self-locking refill containers to prevent mismatching between refill containers and drug chambers.03-08-2012
20110071490SYSTEM AND PROCEDURE FOR PLACING A MEDICAL DEVICE PROXIMATE AN OSTIAL LESION USING A CATHETER ASSEMBLY - A catheter system and method 03-24-2011
20120059350SYSTEM AND METHOD FOR PUMPING INTRAVENOUS FLUID - An intravenous fluid pump (IV) contains a disposable part including a fluid chamber having a resilient top membrane and a non-disposable part including a piston abutting a resilient membrane and a vacuum chamber fitted on top of the resilient top membrane. An external pump is used to create vacuum in the vacuum chamber, resulting in the resilient top membrane being held taut. The flow rate through the pump is relatively independent of changes in the pressure of IV fluid on the upstream and the downstream due to changes in the relative elevation of the fluid reservoir and the patient with respect to the fluid pump.03-08-2012
20120059347PLUNGER CONTROL DEVICE FOR A SYRINGE AND ASSOCIATED METHOD - An apparatus and associated method are provided for controlling the plunging action of a syringe. A plunger control device includes an attachment member adapted to fixedly engage a syringe barrel. A translating member is slideably engaged with the attachment member. The translating member includes an elongate guide member slideably engaged with the attachment member such that the translating member is slideable with respect thereto between a proximal end and a distal end of the elongate guide member. The translating member further includes a plunger attachment portion disposed about the distal end of the elongate guide member and adapted to receive a portion of a syringe plunger for coupling thereto. The translating member further includes an engagement member extending from the proximal end of the elongate guide member so as to be spaced-apart from the syringe barrel when the attachment member is engaged with the syringe barrel.03-08-2012
20120157962NEEDLE-FREE INJECTOR - A needle-free injector is disclosed, the injector comprising a nozzle assembly disposed at a front end of the needle-free injector, wherein the nozzle assembly comprises a piston within a nozzle and adapted to extract and contain a volume of fluid to be injected. The injector also comprises a power house adapted to exert an injection force on the piston to inject the fluid from the nozzle. The injector further comprises a release system, wherein the release system comprises a locking member adapted to move between a locked position and an unlocked position, and a releasing member adapted to move the locking member from the locked position to the unlocked position upon exertion of an unlocking force on the releasing member by a user during operation. While the locking member is in unlocked position, the user can activate the power house by exerting a counter force on the injector. The unlocking force and the counter force are in the same direction as the injection force. A method of releasing a needle-free injector is also disclosed.06-21-2012
20120065613Methods and Systems for Interbody Implant and Bone Graft Delivery - A bone graft system for providing bone graft material to a site of interest includes a multiple unit bone graft material loading device and a conduit. The multiple unit bone graft material loading device is configured to accept a plurality of pre-formed bone graft material units and includes a plurality chambers configured to accept a pre-formed bone graft unit. The conduit includes a first opening and second opening. The first opening is operably connected with the multiple unit bone graft material loading device to accept bone graft material from the multiple unit bone graft material loading device. The second opening is configured to deliver bone graft material to a site of interest.03-15-2012
20110092949IMMUNOISOLATION PATCH SYSTEM FOR CELLULAR TRANSPLANTATION - An immunoisolation patch system, and particularly a patch system comprising multiple immunoisolation microcapsules, each encapsulating biological material such as cells for transplantation, which can be used in the prophylactic and therapeutic treatment of disease in large animals and humans without the need for immunosuppression.04-21-2011
20110092948Remotely Activated Piezoelectric Pump for Delivery of Biological Agents to the Intervertebral Disc and Spine - The present disclosure describes a remotely activated piezoelectric pump for delivery of biological agents to the intervertebral disc and spine in order to achieve spinal fusion. A spinal pump is implanted on the vertebrae of a patient and a spinal cage is inserted in between two adjacent vertebrae after removal of the vertebrae disc. A piezoelectric motor drives the pump and pushes osteogenetic agent through the spinal cage and into a sponge disposed within the cage. The pump is charged by an external removable induction belt worn by the patient. Delivery duration and delivery frequency may be changed before implantation of the spine pump according to the specific needs of the patient. The current device employs a mathematical model that enables the regulation as well as attenuation of the bone fusion process by extending and generalizing the model to enhance and optimize the delivery of osteogenetic agent in a regulated manner.04-21-2011
20120209243FLUID DELIVERY SYSTEM - The disclosure is directed to a fluid delivery device and a removable cartridge system, and methods of use thereof.08-16-2012
20120065614POLYIONIC TRANSITIONAL METAL PHOSPHORESCENT COMPLEX/POLYMER HYBRID SYSTEMS FOR BIOIMAGING AND SENSING APPLICATIONS - A new technique to stabilize transition metal phosphors in a wide variety of stimuli-sensitive polymers and gels is disclosed herein. Other than stabilization in stimuli sensitive/biocompatible matrix some of these transition metal based phosphors are also shown to act as phosphorescent crosslinkers that physically or chemically crosslink polymeric chains to form micro/nanoparticles. The microspheres/nanospheres of the present invention show decreased size and photoluminescence enhancement with particularly high sensitization at physiological pH and temperature. The so formed phosphorescent micro/nanospheres are useful for biological or environmental applications including biological labeling, imaging, and optical sensing. The techniques in the present invention enable usage of imaging agents and sensors at very low concentrations and also minimize or eliminate the usage of toxic chemical crosslinkers typically used to synthesize polymeric micro/nanoparticles.03-15-2012
20120065612CATHETER ASSEMBLY - A catheter assembly is disclosed having a catheter adapter and a needle hub. The catheter adapter has an inner lumen with a septum located within the inner lumen. An introducer needle is inserted through the inner lumen. A septum activator also located within the inner lumen, such that a distal end of the septum activator contacts the septum. The septum activator has an internal cavity and a cavity seal forming a surface of the internal cavity.03-15-2012
20120157961DEVICE AND METHOD FOR DETECTING CHEMICAL AND BIOLOGICAL AGENTS - A device and method capable of sensing the presence of biochem agents, and preferably also capable of delivering precise amounts of one or more antidotes to treat a victim exposed to the agents. The device includes a freestanding tube portion having an internal passage containing a substance selective to a chemical or biological agent so that matter accumulates within the freestanding tube portion when a fluid drawn through the tube portion contains the agent. When vibrated at resonance, the resonant frequency of the tube portion is indicative of the accumulation of matter and thereby the presence of the agent to which the substance is selective. The device then preferably delivers precise amounts of one or more appropriate antidotes to treat the victim. The device is a sufficiently small and lightweight unit to permit being carried by an individual.06-21-2012
20110066133INTRACRANIAL CATHETER - A catheter having an outer profile which is formed such that a path length along an outer surface of the catheter is greater than the corresponding length of the catheter, and to a method for determining the shape of a catheter, and wherein the elasticity and/or conductivity of the tissue into which the catheter is to be introduced is taken into account in order to determine the outer profile of the catheter.03-17-2011
20110066132Internal dry powder delivery system and method thereof - An internal dry powder delivery system through a working channel of an endoscopic cannula for directly applying the powder form medication to an internal tissue/organ site, includes an elongated tubular delivery channel and a powder supply device for producing pressurized gas mixing with the dry powder for feeding to form a mixture of dry powder and pressurized gas delivering to an internal tissue/organ site through the delivery channel via endoscopic cannula. It ensures a smooth powder release by preventing liquid from accumulation at the tip of the delivery channel and offers physicians a new powder form drug delivery method via endoscope. Also, it offers new minimal invasive application by directly and precisely applying the powder format drug to the internal sites of human gastrointestinal organ via endoscope to achieve hemostasis, anti-inflammation, anti-ulcer and anti-tumor treatment, etc.03-17-2011
20110106048FLUID FLOW CONTROL SYSTEM HAVING CAPILLARY FLUID FLOW RESTRICTOR - A fluid flow rate control system and method comprises a capillary tube having a proximal end that projects into a chamber with a cross-sectional area that is larger than or equal to the fluid supply tube's cross-sectional area. The inner cross-sectional area of the capillary tube is configured less than the inner cross-sectional area of the chamber. The chamber has a volume large enough to slow the fluid conducted to it by the upstream fluid line to permit contaminants to fall out of solution. In another aspect, a sleeve is used to mount the capillary tube into the chamber. The sleeve provides a mounting surface for tube segments from the pump and downstream of the capillary restrictor.05-05-2011
20110106047METHODS, DEVICES, AND SYSTEMS FOR PARALLEL CONTROL OF INFUSION DEVICE - A tubing set is disclosed that includes a first line having first and second ends, a bag spike at the first end configured for connection to a source of infusate, and a connector at the second end configured for connection to a blood line. The first line can have a pumping portion for engagement with an infusate pump. The tubing set can also include a second line having first and second ends, the second line first end being attached to the first line between the first line pumping portion and the first line second end and the second line second end being configured for connection to the first line between the first line first end and the first line pumping portion. The tubing set can further include a check valve located in the second line, the check valve having a predetermined cracking pressure of at least 200 mm Hg. The second line second end can be configured for connection to the first line by a dual lumen spike such that when a container is connected to the dual lumen spike, a bypass loop is formed that permits a flow from a second end side of the pumping portion to the first end side of the pumping portion. The first line can include a spike septum at the first end thereof.05-05-2011
20100094246LONG-TERM FEED - ELDERLY - The present invention provides methods of providing long-term and tube-fed nutrition to patients requiring same. More specifically, the present invention provides methods and compositions for providing long-term nutrition to an elderly patient.04-15-2010
20100094250ROTATING STENT DELIVERY SYSTEM FOR SIDE BRANCH ACCESS AND PROTECTION AND METHOD OF USING SAME - A system for treatment of a vessel bifurcation and its method of use comprises a catheter having a catheter shaft, a portion of which is characterized as an axle about which a rotatable assembly is disposed and rotatable thereabout. The system employs a series of lumens, openings and/or ports to provide a balloon mounted on the rotatable assembly with fluid communication to the catheter shaft.04-15-2010
20100094249WOUND TREATMENT APPARATUS AND METHODS - An wound treatment device includes a housing and a treatment tip. The housing retains a volume of treatment fluid. The treatment tip includes a recess, a peripheral edge surrounding the recess, and a fluid channel in view of communication with the recess and the volume of treatment fluid. The recess may be sized to enclose at least a portion of a wound such as an acne member on a person's skin. The recess is sized to retain a volume of the wound treatment fluid when the peripheral edge is sealingly engaged with a skin surface surrounding at least a portion of the wound.04-15-2010
20100094248MULTI-WINDOW GUIDE TUNNEL - Described herein are devices and methods for delivering implants that comprise multiple coupled anchors. The anchors are secured to tissue using a multi-opening guide tunnel that is configured to releasably retain one or more portions of the implant located between two of the anchors. The releasable retention of one or more intervening portions of the implant maintains the position of the implant and the guide tunnel until the implant is secured to the tissue. The multi-opening guide tunnel permits securement of the multiple anchors without requiring repositioning of the guide tunnel for each anchor.04-15-2010
20120123383VESTIBULAR STIMULATOR - A method for providing relief from Meniere's disease, includes reversibly disabling vestibular function following detection of an attack of Meniere's disease following detection of an attack of Meniere's disease.05-17-2012
20090131904INTERNAL THREADS IN TUBING - Embodiments of the present invention provide an internally threaded tube of virtually limitless length that can be easily and reliably constructed. In one aspect, the invention provides an internally threaded tube that includes a tube casing and a coil. A ratio of the length of the tube casing to the inner diameter of the tube casing can be greater than 5:1. The coil can be positioned coaxially within the tube casing. In this position, the coil can exert a radially outward force on the inner surface of the tube casing, which can aid in bonding. A portion of the coil can be specially adapted to be bonded to the tube casing. Methods of creating internally threaded tubes and methods of spirally delivering surgical components with internally threaded tubes are also disclosed.05-21-2009
20120165780MONITORING THE OPERATING HEALTH OF A FORCE SENSOR IN A FLUID INFUSION DEVICE - A device for delivering fluid to a user includes a housing, a drive motor assembly in the housing, a force sensor, and an electronics module. The drive motor assembly regulates delivery of fluid by actuating a piston of a fluid reservoir, and the force sensor generates output levels in response to force imparted thereto during, for example, fluid delivery operations. The electronics module processes the output levels of the force sensor to assess the operating health of the force sensor, to check for occlusions in the fluid delivery path, and to monitor the seating status of the fluid reservoir.06-28-2012
20120165781TARGETED APHERESIS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS - This invention uses “targeted apheresis” to treat rheumatoid arthritis patients. “Targeted Apheresis” is a process whereby the RF and immune complexes responsible for causing the disease symptoms are selectively removed from the blood by passing the blood through a cartridge containing immobilized IgG. The RF and immune complexes are bound out and the cleaned blood is returned to the patient Removal of circulating RF and immune complexes will ameliorate the symptoms of rheumatoid arthritis.06-28-2012
20120215200PRECISION FLUID DELIVERY SYSTEMS - A precision syringe (08-23-2012
20120215199METHODS AND APPARATUSES FOR DETECTING OCCLUSIONS IN AN AMBULATORY INFUSION PUMP - An improved pump, reservoir and reservoir piston are provided for controlled delivery of fluids. A motor is operably coupled to a drive member, such as a drive screw, which is adapted to advance a plunger slide in response to operation of the motor. The plunger slide is removably coupled to the piston. Methods, systems, and articles of manufacture for automatically detecting an occlusion in a medication infusion pump are provided. The electrical current to an infusion pump may be measured. Based on measurements of one or more variables, such as force, the infusion pump detects whether there is an occlusion in the system. The methods of detecting occlusions may be dynamic.08-23-2012
20120215198APPARATUS AND SYSTEM FOR ADMINISTERING MEDICATION - A method and apparatus for administering medication. The method and apparatus includes providing a treatment tube having a wall with an exterior surface and a central lumen. The treatment tube also includes at least one hollow tubular channel disposed within the wall of the treatment tube. Medication is delivered supplied to the hollow tubular channel and delivered through the wall of the treatment tube to the exterior surface of the treatment tube.08-23-2012
20100204672SYSTEM AND METHOD FOR TREATING ISCHEMIC STROKE - A thromboembolic removal system for treating ischemic stroke, including a guide and occlusion catheter, an aspiration catheter, an aspiration pump, and a thromboembolic separator. During aspiration of thromboembolic material through the aspiration catheter, the separator element is advanced from and retracted into the catheter lumen to break up or prevent clogs or flow restrictions formed by the thromboembolic material. Longitudinal channels in the separator allow aspiration through the aspiration catheter to continue even when the separator is disposed in the aspiration catheter lumen.08-12-2010
20100204674Magnetically-Controllable Delivery System for Therapeutic Agents - A magnetic delivery system for delivering a magnetizable particle to a location in a body, the device includes a magnetizable object implanted in the body, wherein the magnetizable object includes a plurality of segments distributed throughout the magnetizable object and wherein the segments are configured to provide a magnetic gradient for attracting the magnetizable particle and an external source of a magnetic field capable of (i) magnetizing the magnetizable particle and (ii) increasing a degree of magnetization of the magnetizable object and thereby creating the magnetic gradient. A drug delivery system including the magnetic delivery system and a magnetizable particle associated with a therapeutic agent and/or a cell. A cell delivery system based on the magnetic delivery system and a magnetizable particle associated with a cell. A method of using the magnetic delivery system for delivery of a therapeutic agent and/or a cell to a targeted location in a body.08-12-2010
20120136333CLOSURE FOR CONTAINERS - Closures for containers and methods for using same are provided. In a general embodiment, the present disclosure provides a closure having a top portion (05-31-2012
20120136334Delivery of Two or More Medicaments Through a Single Dose Selection and Dispense Interface - An injection system for co-delivery of two medicaments (05-31-2012
20110184377METHOD FOR REMOVING CYTOKINES FROM BLOOD WITH SURFACE IMMOBILIZED POLYSACCHARIDES - The present invention is directed to a method for removing cytokines and/or pathogens from blood or blood serum (blood) by contacting the blood with a solid, essentially non micro-porous substrate which has been surface treated with heparin, heparan sulfate and/or other molecules or chemical groups (the adsorbent media or media) having a binding affinity for the cytokine or pathogen(s) to be removed (the adsorbates), and wherein the size of the interstitial channels within said media is balanced with the amount of media surface area and the surface concentration of binding sites on the media in order to provide adequate adsorptive capacity while also allowing relatively high flow rates of blood through the adsorbent media.07-28-2011
20110184375MARKER SEQUENCE FOR NEURODEGENERATIVE DISEASES AND THE USE THEREOF - The present invention relates to new marker sequences for neurodegenerative diseases and the diagnostic use thereof together with a method for screening of potential active substances for neurodegenerative diseases by means of these marker sequences. Furthermore, the invention relates to a diagnostic device containing such marker sequences for neurodegenerative diseases, in particular a protein biochip and the use thereof.07-28-2011
20110184374Peristaltic Pump and Cassette - A cassette for use with a peristaltic pump. The cassette having a body having an exterior. Additionally, the cassette has a sheet attached to the body forming at least one fluid channel. The fluid channel being generally arcuate and projecting outwardly from the exterior of the body. The fluid channel having at least one outlet port for receiving a liquid. Furthermore, the cassette has a liquid trap in fluid communication with and extending at least in part in an upward direction from the at least one outlet port.07-28-2011
20120083761METHODS FOR SELECTIVE ERADICATION OF METASTASIZING CANCER CELLS EX VIVO USING MULTIDOMAIN BIOTAGS - A method for treating cancer in a subject is provided, the method comprising administering to the subject an effective dose of a multidomain biotag that targets one or more cancer cells; establishing a vascular access in the subject; connecting the vascular access to a tube to establish an extracorporeal circulation of a bodily fluid; and exposing the extracorporeal circulation to one or more doses of radiation, killing biotag-targeted cancer cells.04-05-2012
20120083760Flushing a Fluid Line From a Medical Pump - A method and medical pump to perform a flushing procedure are provided. The medical pump is configured to execute the flushing procedure subsequent to an infusion procedure, the flushing procedure and infusion procedure lacking a specified relationship between each other until after performance of the infusion procedure. The method comprises performing an infusion procedure of a medicament with the medical pump and automatically querying in human detectable form whether to execute a flushing procedure in response to conclusion of the infusion procedure.04-05-2012
20120083759Contactless fluid pumping method and apparatus - A fluid pump apparatus for pumping a fluid from a fluid source to a fluid output comprises a first portion, such as a durable portion, and a second portion, such as a disposable portion. The first portion includes a fluid chamber having a wall and an internal cavity, an input port and an output port. A membrane forms a portion of the wall. The first portion further includes a magneto-sensitive element coupled to the membrane. The second portion comprises an actuator configured to contactlessly induce a reciprocating movement of the membrane by application of a time-varying magnetic field to the magneto-sensitive element, thereby facilitating pumping of the fluid through the fluid chamber.04-05-2012
20120172831Methods of Delivering a Health Care Active by Administering Personal Health Care Articles Comprising a Filament - A method of delivering a health care active having the steps of administering to a mammal in need of a health benefit or a treatment for a health condition a personal health care article and consuming the article. The article contains one or more filaments that contain a backbone material, a health care active and optionally aesthetic agents, extensional aids, plasticizers, and crosslinking agents.07-05-2012
20120172832INDEPENDENTLY-MANUFACTURED DRUG DELIVERY MODULE AND CORRESPONDING RECEPTACLE IN AN IMPLANTABLE MEDICAL DEVICE - A drug delivery system for an implantable medical device and methods for making and using the same. Embodiments include a housing of an implantable component of the medical device and one or more at least quasi-solid drug-delivery modules that retain an at least quasi-solid state if not a solid state. The drug-delivery modules and component housing are physically distinct, and as such, may be manufactured independently of each other. The independently-manufacturable drug delivery modules each carry a drug, while the component housing has an exterior surface with one or more recesses formed therein. Associated module(s) and recess(es) are correspondingly dimensioned so that each module may be securely retained within an associated recess via, for example, an interference fit such as by physical interlocking or by friction fit. When so retained in a housing recess, the drug-delivery module and surrounding exterior surface of the housing form a contiguous component surface.07-05-2012
20100049162Mediastinoscopy access, sampling, and visualization kit featuring toroidal balloons and exotracheal method of using - The present invention provides various systems, a kit, and a method for improving access to, sampling within, and visualization of areas within the mediastinal cavity for assisting a surgeon in performing a mediastinoscopy procedure. The access system includes one or more preferably toroidal balloons that can be expanded to dilate and protect the inner walls of a bodily conduit. Instruments pass through hollow spaces within the expanded toroidal balloons. The proximally positioned balloons are expanded first and the unexpanded balloons to be positioned distally are passed through them and subsequently expanded. The sampling system includes an instrument with a rounded head having two or more jaws and a slit therein at the distal end of an elongated tubular body. The visualization system includes a 360° camera that can be positioned from proximal to distal a target site and can also do a U-turn about its axis of extension.02-25-2010
20120179134NEEDLELESS PERMANENT MAKEUP AND TATTOO DEVICE - The present invention relates to methods and compositions for the needleless administration of permanent makeup and tattoos. In particular, the present invention relates to hypodermic injectors for use in delivering pigment or other desired substances to targeted layers of the skin, avoiding needlestick injuries and transmission of disease to the treated subject.07-12-2012
20120179133DIALYSIS MACHINE HAVING MULTI-INPUT VOLTAGE CAPABLE HEATER - A method for heating medical fluid with different supply voltages comprising: configuring first, second and third switches in electrical communication with first and second power lines, the switches configured such that (i) in a first switch state first and second heater elements are placed in series, solely via a closing of the first switch, for operation with a first supply voltage applied to the first and second power lines, and (ii) in a second switch state the first and second heater elements are placed in parallel, via the second and third switches, for operation with a second supply voltage applied to the first and second power lines, and configuring a control element to automatically set the switches in the first or the second switch state based upon a signal sent to the control element indicative of the first or the second supply voltage.07-12-2012
20120179132SYSTEM AND METHOD FOR DIFFERENTIATING CONTAINERS IN MEDICATION DELIVERY - The present invention relates to a fluid delivery system that comprises a fluid container having a chamber structured to hold a fluid therein and a delivery device operable to control delivery of a fluid from the chamber of the fluid container. The fluid container includes a geometric mating member extending from an outer surface thereof. The delivery device includes a geometric mating receptacle structured to mate with at least a portion of the geometric mating member of the fluid container to verify compatibility of the fluid container with the delivery device. Alternatively or additionally, the fluid container may include a first data fixture component and the delivery device may include a second data fixture component that cooperates with the first data fixture component of the fluid container to verify compatibility of the fluid container with the delivery device.07-12-2012
20120179130INTEGRATED INFUSION PUMP AND CONTAINER - An integrated pump module is disclosed that includes a rigid housing having a fluid outlet, a fluid reservoir within the housing, and a pumping segment coupled between the fluid reservoir and the fluid outlet. The pumping segment is configured to cause fluid to flow from the fluid reservoir to the fluid outlet.07-12-2012
20100274216METHOD AND SYSTEM FOR MEASURING FLOW AT PATIENT UTILIZING DIFFERENTIAL FORCE SENSOR - A fluid delivery system and method for measuring flow at a patient utilizing a differential force sensor in order to precisely control the flow of fluid at very low flow rates. The system includes a fluid line through which a fluid is conveyed to the patient, and a flow controller that selectively varies a rate of flow of the fluid through the fluid line. The differential force sensor can be mounted very close to a point of entry of the fluid into the patient's body. An onboard communications device is controllably coupled to the flow controller and to the force sensor, responds to an output signal, and provides a feedback to the flow controller in a closed-loop process. The system can pump the fluid at a higher frequency until the flow rate is actually reached at the patient and then adjust to the flow rate needed to ensure patient health.10-28-2010
20120253313ASPIRATION CATHETERS FOR THROMBUS REMOVAL - Systems for less invasive medical procedures comprise a filter device mounted on an integrated guiding structure and an aspiration catheter. These components can be used together or separately, and the system can be used with other medical devices that are designed for less invasive procedures, such as procedures in a patient's vasculature. The catheter can have a radiopaque band that is held in place under metal wire embedded within the polymer forming the tube of the catheter. In some embodiments, the aspiration catheter has a small diameter distal portion that can access into small diameter vessels in which the distal portion has a smaller average diameter than the remaining tube of the catheter.10-04-2012
20120259308Goal-directed fluid therapy - A method includes setting a hydration goal and administering a diuretic to the patient to induce increased urine flow and collecting urine expelled by the patient. The amount of urine expelled by the patient is determined based on the collected urine. The patient is infused with fluid from a fluid source. The amount of fluid infused into the patient is determined. Diuresis is induced by automatically and continuously adjusting the amount of fluid infused into the patient from the fluid source to meet the hydration goal based on the set hydration goal, the determined amount of urine expelled by the patient and the fluid infused.10-11-2012
20120226258DEVICE AND METHOD FOR ELIMINATING BIOLOGICALLY HARMFUL SUBSTANCES FROM BODILY FLUIDS - A device for purification of blood, blood substitutes or solutions for the introduction into the human and/or animal blood circulation and for gas exchange in blood, blood substitutes or solutions for the introduction into the human and/or animal blood circulation, includes at least one gas permeable membrane and a carrier, coated with substances for adsorptive removal of toxins of biological and chemical synthetic origin, their metabolites and degradation products present in blood, blood substitutes or solutions for the introduction into the human and/or animal blood circulation, a use of the aforementioned device and a process for gentle and simultaneous removal of toxins of biological and chemical synthetic origin, their metabolites and degradation products present in blood, blood substitutes or solutions for the introduction into the human and/or animal blood circulation and for enrichment of blood, blood substitutes or solutions for the introduction into the human and/or animal blood circulation with oxygen.09-06-2012
20120232517Dose Display Mechanism for a Drug Delivery Device - This invention relates to a dose display mechanism for a drug delivery device that allows the user to select multiple doses of an injectable drug and for the dispensing of the set dosage of the drug and applying said drug to a patient, preferably by injection.09-13-2012
20100185172DIAGNOSTIC CATHETERS, GUIDE CATHETERS, VISUALIZATION DEVICES AND CHORD MANIPULATION DEVICES, AND RELATED KITS AND METHODS - Described herein are devices, methods and kits for assessing and/or enhancing the accessibility of a subvalvular space of a heart, accessing the subvalvular space of the heart (e.g., to provide access for one or more other devices), and/or positioning one or more devices in the subvalvular space of the heart. The devices described herein may, for example, comprise catheters that may be used to manipulate one or more chordae tendineae, diagnostic catheters having different sizes and/or shapes (e.g., different curvatures), guide catheters having different sizes and/or shapes (e.g., different curvatures), and visualization catheters. In some variations, the devices, methods, and/or kits may be used to visualize a target site, such as a subannular groove of a heart valve. In certain variations, the devices, methods, and/or kits may be used to manipulate chordae tendineae to provide additional space in a ventricle of a heart (e.g., enhancing the accessibility of the ventricle).07-22-2010
20110004189SYSTEM AND METHOD FOR PROVIDING OPTIMAL CONCENTRATIONS FOR MEDICATION INFUSIONS - Techniques for medical infusions include determining a first infusion rate for administering a first medication to a patient. A fluid load is determined based at least in part on the first infusion rate. It is determined whether the fluid load exceeds a predetermined threshold based on a fluid maintenance rate. If it is determined that the fluid load exceeds the predetermined threshold, then an action is caused to inhibit administering the first medication to the patient at the first infusion rate.01-06-2011
20110004187Drug Delivery Methods And Related Products - This disclosure relates to drug delivery methods and related products. In some aspects, a method includes selecting a drug vial combination by comparing a prescribed drug dosage to a dosing schedule, and delivering substantially all of the first drug from each of the selected drug vials to a patient by operating a pump of a drug delivery device to which the drug vials are connected.01-06-2011
20110004186FLUID DELIVERY SYSTEMS AND METHODS HAVING WIRELESS COMMUNICATION - A fluid delivery system includes a disposable portion and a non-disposable portion configured to communicate with each other wirelessly. The disposable portion includes electrical elements such as one or more sensors configured to be in sensing proximity of fluid, a processor, a memory and a transceiver. The transceiver is configured to receive radio frequency energy from a transmitter located on the non-disposable portion and power the electrical elements on the disposable portion. The non-disposable portion wirelessly controls the disposable portion during a fluid delivery session by programming operational parameters and monitoring fluid delivery measurements over the wireless communication link.01-06-2011
20120238996METHODS OF TREATING CARDIAC ARRHYTHMIA - Methods and apparatus of embodiments of the invention are adapted to treat tissue inside a patient's body. Aspects of the invention can be used in a wide variety of applications, but certain embodiments provide minimally invasive alternatives for treating atrial fibrillation by delivering a tissue-damaging agent to selected areas of the heart. One exemplary embodiment of the invention provides a method of treating cardiac arrhythmia. This method includes positioning a distal tissue-contacting portion of a body in surface contact with a tissue surface of cardiac tissue; detecting the surface contact between the tissue-contacting portion and the tissue surface; and thereafter, injecting a tissue-ablating agent into the cardiac tissue through the tissue-contacting portion of the body.09-20-2012
20120238991Pump Activated Pinch Clamp - A system for controlling flow of a fluid in a tube with a controlling device includes a pinch clamp. The pinch clamp has a first leg, a second leg, a connecting region there between, a pinching region, and a first part of a quick release connector. The first leg and the second leg are both connected to the connecting region. Whether the pinching region is in an open position or in a closed position is determined by spacing between the first leg and the second leg. The first leg includes the first part of the quick release connector. The first part of the quick release connector includes an element for quickly mounting the pinch clamp to the controlling device and for quickly dismounting the pinch clamp from the controlling device.09-20-2012
20120238998Octanoate-reduced Human Albumin - A method is described that improves the transport properties of albumin produced on an industrial scale, wherein the albumin is mixed, during the production process, with substances that saturate the binding points on the albumin. Furthermore, pasteurized and then octanoate-reduced human albumin and therapeutic uses of such albumin is described. Such albumin may be useful in detoxifying human plasma, e.g. for the intravenous treatment of acute or chronic liver diseases, and as a dialysate in extracorporeal liver dialysis.09-20-2012
20120238994TWO-PIECE INJECTABLE DRUG DELIVERY DEVICE WITH HEAT-CURED SEAL - The invention provides a drug delivery device for latanoprost or latanoprost acid. The device has a core of latanoprost or latanoprost acid which is surrounded by an internal and external sheath. The external sheath has a first cap that is permeable to latanoprost or latanoprost acid. The first cap may comprise polyvinyl alcohol (PVA), and the PVA may be heat cured. In certain aspects, there are one or more additional caps on the ends of the sheaths formed from one or more polymers. In certain aspects, one or more portions of the drug delivery device is substantially impermeable to latanoprost or latanoprost acid. In certain aspects, the latanoprost or latanoprost acid elutes through the first cap into a biological environment. The invention further provides methods for manufacturing the drug delivery device.09-20-2012
20120238993TWO-PIECE INJECTABLE DRUG DELIVERY DEVICE WITH HEAT-CURED SEAL - The invention provides a drug delivery device for one or more drugs. The device has a drug core which is surrounded by an internal and external sheath. The external sheath has a first cap that is permeable to at least one drug in the core. The first cap may comprise polyvinyl alcohol (PVA), and the PVA may be heat cured. In certain aspects, there are one or more additional caps on the ends of the sheaths formed from one or more polymers. In certain aspects, one or more portions of the drug delivery device are substantially impermeable to one or more drugs in the drug core. In certain aspects, the drug elutes through the first cap into a biological environment. The invention further provides methods for manufacturing the drug delivery device.09-20-2012
20120238992ANCHORING APPARATUS AND METHODS FOR USE - An apparatus for securing an implantable lead within tissue of a patient includes a base adapted to be secured to a patient's skull adjacent a craniotomy. The base has an upper surface and a lower surface with a central passage therebetween. The central passage is adapted to receive the implantable lead therethrough. The apparatus also has a cover that is releasably coupled to the base so as to substantially cover the central passage and capture the implantable lead therebetween. A first rotating member is also coupled with the base and the first member is rotationally movable so as to meet and engage the implantable lead at a plurality of positions within the central passage.09-20-2012
20120265164FLOW RESTRICTOR FOR MEDICAL DEVICES - This relates to fluid delivery devices and methods and, more particularly, to implantable fluid delivery devices and methods of use. A flow restrictor for medical devices is described with particularly useful properties.10-18-2012
20120323213THERMO-CHEMICAL MEDICAL DEVICE FOR MANIPULATION OF TISSUE - The present invention provides a medical device for manipulation of tissue of a patient. The medical device comprises a shaft having a proximal section extending to a distal section that has a closed distal end portion. The shaft has a plurality of lumens formed therein including a first lumen and a second lumen. The first lumen is for distally advancing a first reactant through the proximal section. The second lumen is for distally advancing a second reactant through the proximal section. Positioned longitudinally within the shaft and distally from the first and second lumens is a mixing element. The mixing element is in fluid communication with the first and second lumens. The mixing element has a series of baffles for mixing the first and second reactants together producing a reaction product to heat the closed distal end portion of the shaft for manipulation of the tissue.12-20-2012
20120323211Coated Balloons for Blood Vessel Stabilization - A coated balloon device for stabilizing a section of a blood vessel in a living subject is disclosed. The coating layer of the coated balloon comprises a phenolic compound having a plurality of phenolic groups connected to form a hydrophobic core with peripheral phenolic hydroxyl groups. The coating layer of the coated balloon may contain a hydrophilic polymer to facilitate the release of the phenolic compound. The balloon in general is made of a compliant polymer for atraumatic contact with the blood vessel. In some embodiments, the coating of the coated balloon device further comprises a hydrophilic undercoat layer between the balloon and the coating layer. In some embodiments, the coated balloon device further comprises a sacrificial top coating that dissolves upon delivery into the section of the blood vessel and comprises a hydrophilic composition including sugar, sugar derivatives, or a combination thereof.12-20-2012
20120323212DISTRIBUTED MEDICATION DELIVERY SYSTEM AND METHOD HAVING AUTONOMOUS DELIVERY DEVICES - A pump operations module having a base function includes only base function programming in the module itself but is configured to receive advanced delivery programs in a buffer for execution autonomously. An advanced interface module (AIM) is used to prepare advanced delivery programs and upload them to one or more delivery modules as well as monitor the performance of those modules. However, the advanced interface module does not control the execution of those advanced delivery programs by the pump operations modules. The AIM includes a touch screen and access to drug libraries. The AIM will generate graphical slide controls on the touch screen with the minimum and maximum values on the touch screen for the user to create an advanced delivery program for upload, to greatly lessen the risk of errors. Support for PK applications is provided.12-20-2012
20120271271NEONATAL FLUID TUBING HEATER - A heating system for warming nutritional liquid fed to a neonate or preterm infant may comprise a control module and a heater. The heating system is portable so that the heating system is not connected to a syringe pump or other device used to feed the neonate. The heater of the heating system is mounted to the tube that is used to feed the neonate. The heater is positioned along the tube in close proximity to the neonate so that a temperature drop of the nutritional liquid after the nutritional liquid exits the heater and reaches the neonate is negligible. The heater raises the temperature of the nutritional liquid to a target desired temperature (e.g., body temperature of the mother and neonate or to a temperature above the temperature of the mother and neonate) so that the neonate may consume warm nutritional fluid. Once the nutritional liquid reaches the neonate, the nutritional liquid is at about the body temperature of the mother or neonate or at least above room temperature.10-25-2012
20120271272DEVICE FOR OCULAR ACCESS - The present invention provides devices to access the suprachoroidal space or sub-retinal space in an eye via a minimally invasive transconjunctival approach. The devices may also be used after a partial dissection, for example after dissection of the outer scleral layer of the eye, and using the device within the dissection to access the suprachoroidal space or the sub-retinal space.10-25-2012
20090318887ENTERAL FEEDING PUMP SYSTEM - An enteral pump system for delivering medical fluids unidirectionally includes a disposable fluid delivery set having a repeatable compression portion and an enteral feeding pump. The repeatable compression portion is helically coiled around a central axis to define a cylindrical shape. The compression portion is configured to pump a large volume of medical fluids per stroke. The compressing portion includes at least two adjacent tubing walls joined around the central axis for repeatable compression. The enteral feeding pump is configured to repeatedly and reliably compress the compression portion of the fluid delivery set along the central axis. In operation, the compression portion is repeatably compressed without distortion along the central axis by the enteral feeding pump to flow unidirectionally through the fluid delivery set.12-24-2009
20110238034Method and Apparatus for Guiding an External Needle to an Implantable Device - A support tool for a supply assembly delivers a functional fluid to an implantable medical device. The supply assembly defines a supply axis. The support tool includes a support member defining an opening. The opening has a support axis, and the opening is configured to receive the supply assembly. The support member includes a three dimensionally contoured nesting surface that conforms to a corresponding three dimensionally contoured surface of the supply assembly. The corresponding surface of the supply assembly nests against the nesting surface to support the supply assembly such that the supply axis remains substantially fixed relative to and aligned with the support axis.09-29-2011
20110238035TREATMENT OF OBESITY AND/OR TYPE II DIABETES BY STIMULATION OF THE PITUITARY GLAND - Methods of treating obesity and/or type II diabetes include applying at least one stimulus to the pituitary gland of a patient with an implanted stimulator in accordance with one or more stimulation parameters. The at least one stimulus is configured to treat obesity and/or type II diabetes. Systems for treating obesity and/or type II diabetes include a stimulator configured to apply at least one stimulus to the pituitary gland of a patient in accordance with one or more stimulation parameters. The at least one stimulus is configured to treat obesity and/or type II diabetes.09-29-2011
20110238032MULTIPLE DRUG INFUSION SYSTEM AND METHOD - A drug infusion system includes an infusion pump; an input device; and a processor, the input device and processor configured to allow an operator to make a selection that specifies a combination of a plurality of drugs to be delivered to a patient, the input device and processor further configured to allow the operator to enter the weight of the patient, at least one of the plurality of drugs delivered based on the entered weight of the patient.09-29-2011
20100234826Medicament Dispensing Devices and Methods - A medicament dispensing device including a substantially rigid carpule body which has a dispensing end and an actuation end opposite the dispensing end. The carpule body is substantially tubular and thus defines a carpule bore. The device further includes a plunger operatively disposed within the carpule bore having a plunger actuator near the actuation end of the carpule body and a plunger tip opposite the plunger actuator. The plunger tip and an orifice at the dispensing end of the carpule bore define a medicament volume which may be loaded with a medicament selected to achieve specific therapeutic goals. The carpule body may also include a wound depth scale. The depth scale is typically associated with the dispensing end of the carpule body. Similarly, the medicament dispensing device may include a dosage scale. Also disclosed are methods of dispensing medicaments.09-16-2010
20120277720SELECTIVE CYTOPHERESIS DEVICES AND RELATED METHODS THEREOF - The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.11-01-2012
20120277719COATING COMPOSITIONS, METHODS AND COATED DEVICES - The present disclosure provides, am ng other things, a coated device comprising: a porous substrate; a film coating at least part of the substrate, which film comprises a multilayer unit comprising a first layer and a second layer adjacent to the first layer, wherein the first layer comprises a first polymeric material and at least first interacting moiety, wherein the second layer comprises a second polymeric material and at least second interacting moiety, and wherein the interacting moieties on adjacent layers interact with one another so that the adjacent layers are associated with each other into the film; and an agent for delivery associated with the coated device, such that decomposition of one or more layers of the film results in release of the agent.11-01-2012
20120277718PIVOTING RING SEAL - The instant invention provides for a pivoting ring that can be used as a seal for an inflatable member. The pivoting ring seal offers a mechanical action which acts to tighten with increasing inflation and/or expansion of an inflatable member. As the inflatable member increases in pressure and/or size, one side of the ring is lifted and pivots around a fulcrum in the middle of the ring seal causing the opposite side of the ring seal to decrease in diameter. The pivot ring causes the opposite part of the seal to tighten about an inner member allowing for a higher-pressure seal. In addition to a higher pressure seal, the working length of the inflatable member can be adjusted by moving the ring along the length of the inflatable member.11-01-2012
20120277721SURGICAL INSTRUMENT FOR INJECTING A DRUG INTO PROSTATE TISSUE - A needleless injector including a body at a proximal end, a shaft extending distally from the body, at least one injection orifice at a distal end of the shaft in fluid communication with a fluid chamber at the proximal end, a pressure source in communication with the fluid chamber, and a tissue tensioner located at the distal end of the shaft proximal to the injection orifice, wherein the distal end including the tissue tensioner and injection orifice is positionable within a urethral lumen so that when the tissue tensioner is deployed, tissue of the urethra is tensioned at a location for injection of fluid from the injection orifice into the tissue of the urethra.11-01-2012
20110251580POWDER DELIVERY DEVICE - A device for the topical dispensing of a powder, typically a powder medicament, comprises, or is adapted to be coupled to, a powder receptacle and a gasflow generator. The gasflow generator is adapted, in use, to cause gas to flow through the device, which further comprises an agitator by which the powder and/or the powder receptacle can be mechanically agitated. Actuation of the gasflow generator, which causes gas to flow through the device and to entrain powder from the powder receptacle, thereby to dispense powder from the device, is accompanied by actuation of the agitator, causing the powder receptacle to be mechanically agitated, thereby facilitating the release of powder from the powder receptacle.10-13-2011
20110270215 COMPOSITION COMPRISING NOR-ADRENALINE AND A NET INHIBITOR FOR ADMINISTERING TO A BRAIN-DEAD, HEART-BEATING POTENTIAL ORGAN DONOR - A composition, an infusion solution, a method for treatment, and a kit for intravascular administration for treatment of a brain-dead, heart-beating, respirated, potential organ donor. The composition has a non-adrenaline and NET inhibitor for noradrenaline. The NET inhibitor may be cocaine or an analogue thereof or a tricyclic antidepressant. The composition may in addition include adrenaline, hydrocortisone, thyroxin, insulin, triiodotyronine, dopamine, a vasopressor agent, such as desmopressin, and methylprednisolone. The ratio between the NET inhibitor and nor-adrenaline is about 1:1. The composition may be dissolved in pure water, Ringer's acetate solution or physiological sodium chloride solution. The composition is infused in such an amount as to maintain a mean arterial pressure of about 60 mmHg. The composition may be infused by a pump at a rate of about 1.7 ml/hour decreasing dose-dependent to about 0.4 ml/hour after 24 hours.11-03-2011
20120089114INJECTION METHODS USING A SERVO-CONTROLLED NEEDLE-FREE INJECTOR - A method for injecting a substance through a biological body surface includes providing a needle-free transdermal transport device configured to inject the substance through the surface. The substance is injected into the biological body with the transport device while a parameter of the injection is sensed and a servo-controller is used to dynamically adjust at least one injection characteristic based on the sensed parameter. The substance is injected for (i) a first time period during which a first portion of a volume of the substance is injected at a first injection pressure, and (ii) a second time period during which a remainder of the volume of the substance is injected at a second injection pressure. A viscosity of the substance may be determined, and a pressure calculated for injecting the substance based on the viscosity. The substance may be injected with the transport device by using the calculated pressure.04-12-2012
20120089113INTRAOCULAR DRUG DELIVERY DEVICE AND ASSOCIATED METHODS - Devices, systems, and methods for delivery of an active agent into the eye of a subject can include an ocular active agent delivery device (04-12-2012
20120095436Methods and Apparatus for Translating a Continuous-Delivery Delivery Profile Into a Plurality of Periodic Bolus Deliveries - Methods and apparatus for translating a continuous-delivery delivery profile into a plurality of periodic bolus deliveries.04-19-2012
20120095433INFUSION SYSTEM USING OPTICAL IMAGER FOR CONTROLLING FLOW AND METHOD THEREOF - An infusion pump, including: a microprocessor; a drip chamber; a drip tube with an end in the drip chamber; and an illumination system: with a light source for transmitting light through the drip chamber to a drop of fluid suspended from the drip tube; and for controlling illumination properties of the light transmitted to the drop. The pump includes an optical system for: receiving light transmitted through the drop; and transmitting, to the microprocessor, data regarding the received light. The microprocessor: generates, using the data, an image of the drop; locates, using the image, an outer edge of the drop to define a boundary of the drop; integrates an area enclosed by the boundary; and calculates a volume of revolution for the drop with respect to an axis for the drop that intersects the end of the drip tube, assuming symmetry of the drop with respect to the axis.04-19-2012
20120095432CATHETER AND METHOD OF INSERTION - A balloon catheter system includes a tube and a dilator detachable from the tube after the tube is inserted into a cavity in the patient. The cavity may be filled with gas or liquid to expand the viscera surrounding the cavity and the guidewire may be inserted using a trochar, for example. The tube includes one or more lumen to expandable balloons that are inflatable by fluid inserted through the lumen and into the balloon or balloons, which are formed by elastic film sealed on opposite ends to the external diameter of the tube. The dilator is held in place during insertion, such as by a stainless steel shaft and a sheath portion of the dilator extending over the end of the tube being inserted into the cavity. A portion of the sheath may extend over and protect the balloon. A retractor net may be used to capture and remove the dilator or the dilator may be designed as a bioabsorbable or digestible material or of a material that passes safely through the digestive tract of a patient.04-19-2012
20120330270Dispensing Fluid from an Infusion Pump System - Some embodiments of an infusion pump system include a drive system that advances a piston rod to dispense medicine to a user. Moreover, the drive system can be configured to reliably dose selected amounts of medicine to the user while also reducing the likelihood of inadvertent dispensing of medicine in response to impacts or pressure changes exerted upon the infusion pump system.12-27-2012
20120330273IMPLANTABLE MEDICAL DEVICE WITH TIME FOR THERAPEUTIC OUTPUT REPLENISHMENT DETERMINATION AND METHOD THEREFORE - An implantable medical device for producing a variable therapeutic output to a patient. A therapeutic output delivery module requires replenishment following delivery of a predetermined amount of the therapeutic output. A calculator is responsive to a measure of an amount of the therapeutic output actually delivered to the patient for determining a parameter representative of a time at which the therapeutic output delivery module of the implantable medical device should be replenished with the therapeutic substance based at least in part upon the amount obtained from the measure. A method determines a parameter representative of a time at which a therapeutic output module of an implantable medical device should be replenished following delivery of a predetermined amount of therapeutic output. An amount of the therapeutic output actually delivered to the patient is measured. The parameter is calculated based at least in part upon the amount obtained in the measuring step.12-27-2012
20120330272SELF-CONTAINED PORTABLE APPARATUS FOR ADMINISTRATION OF A DRUG SOLUTION - A self-contained portable apparatus for administration of a drug solution includes a housing having an enclosure for receiving a flexible pouch containing a drug solution, the output of which is connectable to a conduit for delivering the drug solution to a recipient. A pressurization system is arranged for providing a constant and controllable gas pressure to the housing in order to obtain a controllable delivery of the drug solution. The pressurization system includes a pressure source for delivering positive pressure gas; a pressure accumulation tank connected to the source and the second chamber; a one-way valve arranged between the pressure source and the pressure accumulation tank; and a mechanical pressure regulator arranged between the pressure accumulation tank and the housing. Hereby, an extremely stable and well controllable output pressure and output flow is obtainable.12-27-2012
20120330271Method and Apparatus for the Containment of a Surgical Site - An apparatus for the containment of a surgical site includes an enclosure, with at least one port, securely coupled to the surgical site and a source of pressurized fluid in fluid communication with the enclosure via the at least one port providing pressurized fluid to the surgical site. The pressurized fluid establishes a hemostatic equilibrium within the enclosure by reducing blood egress through injuries in blood vessels at the surgical site thereby preventing bleeding at the surgical site. A method for the containment of a surgical site includes securely coupling an enclosure to a surgical site; fluidly coupling a source of pressurized fluid to the enclosure; and continuously providing pressurized fluid to the enclosure from the source of pressurized fluid and draining fluid from the enclosure. The pressurized fluid establishes a hemostatic equilibrium within the enclosure.12-27-2012
20110295228MINIMALLY INVASIVE MEDICAL DEVICE AND METHOD FOR DELIVERY OF THERAPEUTIC OR DIAGNOSTIC AGENTS INTO A VESSEL WALL - The invention relates to minimally invasive device for delivering therapeutic or diagnostic agents into a vessel wall. The device includes an introducer tube, a tubular member having a proximal end, a distal end, and a first lumen extending therebetween, the tubular member being slidably disposed within the introducer tube; a plurality of hollow delivery struts, each delivery strut adapted to pierce through inner most layers of the vessel wall and each comprising at least one exit port and at least one stopper to prevent the delivery strut from piercing through the outer most layers of the vessel wall. The delivery struts are disposed on the distal end of the tubular member and are in fluid communication with the first lumen. The invention also relates to methods of delivering the device of this invention and methods of treating conditions or diseases of body lumens.12-01-2011
20110319863MULTI-RESERVOIR IMPLANTABLE PUMP WITH VARIABLE FLOW RATE CAPABILITIES - A multiple reservoir or chambered implantable pumps is disclosed. The pump according to the present invention is particularly useful in allowing for multiple constant flow rates to be provided from an otherwise constant flow implantable pump. The pump is also useful in allowing for housing of multiple active substances. A multiple reservoir implantable pump is also disclosed, which has at least one chamber capable of providing a constant flow rate and at least one chamber capable of being utilized for patient controlled injections. Methods of providing active substances to patients utilizing such pumps are also disclosed.12-29-2011
20110319862DELIVERY DEVICE AND METHOD - A device for automatically delivering a basal flow of a medication to a patient while also permitting manual control over bolus delivery of the medication is disclosed. The device is configured to permit bolus delivery to occur precedent, concurrent with, or subsequent to the basal delivery. A method for performing the same is also disclosed.12-29-2011
20110319861MEDICAL DEVICE MECHANICAL PUMP - A medical device pump with a housing with a compartment for removably receiving a cartridge containing a therapeutic agent, a conduit configured to operatively provide a fluid flow path for therapeutic agent to exit from the cartridge, a user activated delivery button, a trigger mechanism, and a mechanical pump mechanism. The trigger mechanism, user activated delivery button and mechanical pump mechanism of the medical device pump are configured such that the trigger mechanism is activated by a user fully activating the user activated delivery button. Moreover, such full activation generates mechanical power employed by, and sufficient for, the mechanical pump mechanism to pump a predetermined volume of therapeutic agent from the cartridge and through the fluid flow path.12-29-2011
20110319860INTRADERMAL INJECTION DEVICE - Embodiments herein relate to the field of injections, for instance needle-free injections, and more specifically, to methods and apparatus for spring-driven intramuscular and intradermal injections. Provided in some embodiments are needle-free injectors adapted to deliver intradermal injections, as well as vial adaptors that are adapted to function as spacers when used with a needle-free injection device.12-29-2011
20110319859Medical Valve with Fluid Volume Alteration - A medical valve has an open mode that permits fluid flow, and a closed mode that prevents fluid flow. To that end, the medical valve has a housing having an inlet and an outlet, and a resilient member within the housing. The resilient member has a body portion with a free state when undeformed by external mechanical forces and a deformed state when the valve is in the closed mode. The body portion is formed to return toward the free state as the valve transitions from the closed mode to the open mode and defining at least part of a fluid path through the valve.12-29-2011
20120101472MULTI-CHAMBER CELLULAR MIXING AND DELIVERY SYSTEM AND METHOD - A multi-chamber injection and treatment system includes a first chamber, a second chamber, a mixing element, and a needle portion. The first chamber is generally adapted to receive and advance various cells, while the second chamber is adapted to receive and advance adipose tissue, and can blend or reduce the size of the adipose tissue. The mixing element combines the constituents of the chambers and is in communication with the needle portion for driving the cellular mixture into a target tissue site, such as the mid-corpora of the male penis.04-26-2012
20120101471SELF-POWERED INFUSION DEVICE AND METHOD OF USE - A medical device system is provided here which has a disposable pump member capable of delivering fluid at a high pressure and a controlled rate. The disposable pump member has an internal power source that provides an energy source for a drivable pump used during treatment. Additionally, a method is provided herein for infusing, injecting, or delivering an intended fluid into a body vessel at a high pressure and a controlled rate.04-26-2012
20120289928Medical Tubing Installation Detection - This disclosure relates to medical tubing installation detection. In certain aspects, a method is performed by a data processing apparatus. The method includes detecting that a tube is incorrectly installed on a drug delivery device by providing an instruction for a motor of the drug delivery device to pump a drug and receiving, after a period of time has passed since providing the instruction for the motor of the drug delivery device to pump the drug, a signal from a fluid detector connected to the tube, the signal indicating an absence of fluid in the tube.11-15-2012
20100185173METHOD AND KIT FOR DELIVERY OF BRACHYTHERAPY TO A SUBJECT - The present invention provides a kit for delivering catheter brachytherapy to a subject comprising a medical balloon catheter (07-22-2010
20130012915CONNECTING SYSTEM THROUGH WHICH FLUID FLOWS FOR USE IN MEDICINE AND MEDICAL TECHNOLOGY - A connecting system for components through which fluid flows for medicine and medical technology, in particular infusion or transfusion tubes, selector valves, multi-way distributors, injection equipment such as needles, accesses or the like, and combinations thereof, comprising a female tubular receptacle, which comprises an inner receiving section and an outer first fixing section, and/or a male tubular plug element for reception in the female receiving section and an outer second fixing section, which cooperates with the first fixing section for fixing the connecting system. The surfaces of the connecting system that come in contact with the fluid are produced at least in some sections from amorphous copolyester. Use of amorphous copolyester for producing a corresponding connecting system.01-10-2013
20120150140SEMI-RIGID PARTIALLY COLLAPSIBLE BOTTLES - Partially collapsible bottles (06-14-2012
20130018355METHOD AND DEVICE FOR REMOTE MONITORING AND CONTROL OF MEDICAL FLUID MANAGEMENT DEVICES - The invention relates to the field of medical fluid management devices, in particular dialysis machines. The object of the invention is to design methods and devices, such that the monitoring and control of medical fluid management devices from a remote site are possible. To do so, the screen content of the output device of a fluid management device is transmitted at least partially to an output device of a remote control unit. The screen content optionally has user interfaces, which can be selected on the remote control device and lead to changes in the control of the transmitting medical fluid management device.01-17-2013
20110160694Nanotubes as Mitochondrial Uncouplers - A method of uncoupling mitochondria in a subject including administering nanotubes to the subject in a therapeutically effective amount, wherein the nanotubes are self-rectifying is provided. A method of decreasing reactive oxygen species and decreasing detrimental loading of Ca06-30-2011
20130023849METHODS AND SYSTEMS FOR REDUCING VIRAL LOAD OF HEPATITIS C VIRUS IN HEMODIALYSIS PATIENTS - The present technology relates to methods and systems for the removal of pathogens and fragments thereof in hemodialysis patients. In particular, methods and systems are described where lectins can be used to remove the Hepatitis C virus and fragments thereof in hemodialysis patients, and to provide a sustained reduction in viral load.01-24-2013
20130023848INFUSION PUMP ASSEMBLY HAVING A REVERSE ROTATION PREVENTION SYSTEM AND METHOD FOR OPERATING THE SAME - A system and method for preventing an undesirable reverse rotation of an infusion pump assembly. The infusion pump motor includes a roller assembly, a coil, a rotor, a rotor position sensor, and a controller. The rotor is in communication with the coil, and the rotor is rotationally coupled to a roller assembly. If the pump is in not pumping, then the system monitors for reverse rotation of the pump, and if reverse rotation of the pump is detected, energizes the coil in a manner that holds the rotor in place. The system may also activate an indicator if reverse rotation is detected.01-24-2013
20130172846DEVICES, SYSTEMS, AND METHODS FOR EXCAVATING CANCER CELLS - Methods, devices, and systems are provided for guiding tumor movement, particularly in vivo for treatment of patients. The method may include implanting into a tissue site where tumor cells are present a device having one or more surface structures or substrates, such as aligned nanofibers, which provide physical guidance cues for directing the migration of the tumor cells from the first tissue location to a selected second location, for tumor cell extraction or death. The devices and systems may include a cytotoxic agent for contacting tumor cells migrated via the substrate. All or a portion of the at least one substrate may include one or more biochemical cues, such as a coating of laminin or another protein, which may be provided in a concentration gradient to facilitate uni-directional tumor cell migration.07-04-2013
20080255536Methods and apparatuses for treating tonsils - Methods and apparatuses include applying a biting force to a bite-piece, the biting force is applied by a user's teeth, wherein the bite-piece is held inside of the user's mouth. Closing the mouth and the biting force suppress the user's gag reflex and the user's Tonsils and adjacent Throat structures can be treated by spraying fluid onto the Tonsil or manipulating the surface of the Tonsil and related structures. The Tonsils can be cleaned thereby.10-16-2008
20130150819Sub-mucosal agent delivery apparatus,system and method - An agent delivery apparatus for administering a pharmacological agent formulation to a sub-mucosal compartment of a body organ, comprising injector means having an internal formulation chamber that is adapted to receive and contain the pharmacological agent formulation therein and an elongated agent delivery member having a first end that is in communication with the internal formulation chamber and a delivery nozzle end, the injector means including force generating means that is adapted to generate sufficient force to expel the pharmacological agent formulation from the injector means and into and through the agent delivery member, and out of the delivery nozzle end of the elongated agent delivery member with a delivery pressure in the range of approximately 06-13-2013
20130150820NEEDLE-FREE INTRADERMAL INJECTION DEVICE - A needle-free injection device suitable for delivering a therapeutic substance into the intradermal space of a patient. The needle-free injection device includes a main spring which can be compressed using one or more handles attached to the device to place the needle-free injection device into an armed configuration. Device embodiments may optionally include an injector tube and associated apparatus which may be moved relative to other device structures when the injector is pressed against the skin of a patient with sufficient force. The disclosed operational switches and release mechanisms cooperate to prevent injection unless the device is properly positioned for an injection. Needle-free injection systems and methods of operating a needle-free injection device are also disclosed.06-13-2013
20130150821MULTICHANNEL INFUSION SYSTEM FOR RENAL REPLACEMENT THERAPY - A multichannel infusion system for use with a hemofilter includes first and second measurement devices that measure the weight of a replacement fluid in a first receptacle and an ultrafiltrate in a second receptacle, a first pumping module configured to accept a first desired flow rate and deliver the replacement fluid from the first receptacle to the hemofilter at the accepted first desired flow rate, a second pumping module configured to accept a second desired flow rate and remove the ultrafiltrate from the hemofilter to the second receptacle at the accepted second desired flow rate, and a control system in communication with the first and second measurement units and the first and second pumping modules. The control system is configured to adjust the first and second desired flow rates based on the measurements made by the first and second measurement devices.06-13-2013
20080221547Medicine Bottle Configuration and Method of Using Same - A medicine bottle assembly includes a medicine bottle having a storage cavity and an outlet port, with the outlet port disposed on an exterior of the bottle and in fluid communication with the storage cavity. Liquid medicament is disposed in the storage cavity and defines a current fluid level. The outlet port is advantageously disposed entirely below the current fluid level and oriented generally upward. The outlet port is operative to selectively allow flow of the medicament out of the bottle. The assembly may further include a needless syringe having an angled tip. The exterior of the bottle may include a recess disposed above the outlet port, with the recess adapted to receive and retain the syringe. The recess is advantageously aligned with the outlet port. Other aspects and methods are also disclosed.09-11-2008
20080215031Pelvic balloon tamponade - An implantable device is provided for controlling hemorrhage in a body cavity, comprising an expandable balloon and a conduit for supplying a physiologically compatible fluid to inflate the balloon. When the balloon tamponade device is implanted or inserted into the body cavity, it is inflated with a physiologically suitable fluid, so that the balloon generally conforms to the body cavity and exerts compressive force against the walls, tissues or structures of the body cavity to control hemorrhage. The balloon may have a deforming means to limit expansion of the balloon in a direction to facilitate expansion of the balloon in another direction. The device may have additional tubes within the conduit, or a plurality of separate lumens within the conduit or tubes to allow drainage and irrigation to the body cavity. There is also provided a cuff for attachment of an external traction to the balloon tamponade, to facilitate the compressive effect of the device. In a preferred embodiment, there is provided a dual balloon tamponade in which two balloons are axially spaced along the conduit, providing a means to control hemorrhage from two distinct body cavities, such as a uterus and a vagina. There is also provided a method to control hemorrhage in a body cavity by implantation or insertion of the balloon tamponade, inflating the balloon with a fluid to a sufficient pressure and retaining the fluid pressure within the balloon for a sufficient period of time to determine whether hemorrhage has been controlled. A kit comprising the balloon tamponade apparatus is also provided.09-04-2008
20110270217Skin Retention Device for a Medical Jet Injection Kit - A skin retention device 11-03-2011
20130138074Infusion Pump and Method Which Inhibits Unintended Tubing Withdrawal - A delivery tube is inhibited from unintended withdrawal from an infusion pump which has an internal occlusion clamp that clamps the delivery tube to prevent the free flow of fluid through the tube, by overlapping a blocking lip from a compression edge of the occlusion clamp with a restraint surface of an anvil against which the tubing is compressed and by overlapping a blocking projection from the restraint surface with the compression edge. Inhibition is also achieved by positioning an obstruction protrusion adjacent to the compression edge and the blocking lip to resist the application of exterior physical force to force the occlusion clamp from an occluding position to a non-occluding position.05-30-2013
20130123742Method of a Pharmaceutical Delivery System for Use Within a Joint Replacement - Methods and apparatus of providing a joint replacement parts with a pharmaceutical delivery system is provided. The pharmaceutical delivery system is placed within the joint replacement parts to provide, over a period of time, sustained release of a controlled concentration of pharmaceuticals within the joint space of the joint replacement and to produce a local or systemic physiological of pharmacological effect.05-16-2013
20130131629NANOCHANNELED DEVICE AND RELATED METHODS - Apparatus and methods of delivering a therapeutic agent using an implant comprising a nanochannel delivery device.05-23-2013
20130144250IMPLANTABLE DRUG DELIVERY COMPOSITIONS AND METHODS OF TREATMENT THEREOF - A method of treatment, such as treating an estrogen-related disorder or a psychotic disorder, by implanting a reservoir-based drug delivery composition into a subject to systemically deliver a therapeutically effective amount of an active pharmaceutical ingredient (such as an aromatase inhibitor or risperidone) to the subject for a long period of time (e.g., one month or one year). The drug delivery composition may include a rate-controlling excipient (e.g., an elastomeric polymer) defining a reservoir containing at least one discrete solid dosage form (e.g., one or more pellets), which includes an active pharmaceutical ingredient and optionally, a sorption enhancer.06-06-2013
20130144251RENAL NEUROMODULATION METHODS AND DEVICES FOR TREATMENT OF POLYCYSTIC KIDNEY DISEASE - Methods for treating polycystic kidney disease with therapeutic renal neuromodulation and associated systems and methods are disclosed herein. One aspect of the present technology is directed to methods that at least partially inhibit sympathetic neural activity in nerves proximate a renal artery of a kidney of a patient. One or more measurable physiological parameter corresponding to the polycystic kidney disease can thereby be reduced. Moreover, central sympathetic drive in the patient can be reduced in a manner that treats the patient for the polycystic kidney disease. Renal sympathetic nerve activity can be modulated along the afferent and/or efferent pathway. The modulation can be achieved, for example, using an intravascularly positioned catheter carrying a neuromodulation assembly, e.g., a neuromodulation assembly configured to cryotherapeutically cool the renal nerve or to deliver an energy field to the renal nerve.06-06-2013
20130144253CATHETER ELECTRICAL CONNECTOR ASSEMBLY - A catheter includes a catheter sheath, and a handle. The handle includes an electrical connector its proximal end for connecting the catheter to standard electrical devices such as a typical monitoring device. The catheter handle houses an electrical connector assembly. The electrical connector assembly includes a first connector member to which electrical conductors of a catheter sheath are connected and a second connector member, which is further connected to the connector integrated at the proximal end of the catheter handle. The first connector member is received in a socket of the second connector member in a clip-in manner.06-06-2013
20130131628DEVICE AND METHOD FOR SUSTAINED RELEASE OF THERAPEUTIC AGENT - Devices and methods for administering a therapeutic agent, comprising an implantable delivery device. Exemplary embodiments comprise a reservoir in fluid communication with a channeled member, and a solid matter therapeutic agent disposed within the reservoir.05-23-2013
20080200896Device and Method for Treating a Blood Vessel - Device and method for treating a vessel including for example the insertion of a catheter toward a target destination using a guidewire. The catheter may include for example a proximal balloon, being shaped to enable the formation of for example a funnel shape when infated, and a distal balloon. The target destination, for example, a thrombosis, chronic total occlusion or myocardial infarction area may be substantially enclosed by the proximal balloon and the distal balloon.08-21-2008
20110224644Dosing Unit, Ambulatory Infusion Device Comprising Dosing Unit and Method For Operating A Dosing Unit - A dosing unit for an ambulatory infusion device and a method of operation are disclosed. The dosing unit includes a stationary member, a movable member, and a plunger. The movable member and the stationary member, together, make a charging valve and a discharging valve. The plunger is located, at least in part, in a metering cavity of the movable member and the movable member is adapted to selectively couple and decouple a driving unit, such that, by operating the driving unit with the movable member being coupled with the driving unit, the movable member moves with the plunger to maintain a position of the plunger relative to the movable member along a displacement axis, and by operating the driving unit with the movable member being decoupled from the driving unit, the plunger is displaced while the position of the movable member is maintained.09-15-2011
20110224641Magnetic conductive recipient - A magnetic conductive recipient comprising: magnetic field via magnetized water. This process provides means for drug delivery in a molecular state, control of blood circulation, control of internal and/or external cell organism functions, including MWRI (magnetic water resonance imaging).09-15-2011
20100286651Multiple Segmented Peristaltic Pump and Cassette - In various embodiments, a surgical cassette, configured to engage peristaltic pump rollers, may include two or more pump segments between a sheet and a substrate coupled to the sheet. The two or more pump segments on the cassette may produce additional flow (e.g., approximately twice the flow for two segments as opposed to one) than if the cassette had only one pump segment engaging the roller. Further, in some embodiments, the two or more pump segments and rollers on the roller head may be configured to provide a flow profile in which a peak of a pulse from a first pump segment is at least partially out of phase with a peak of a pulse from the second pump segment. The combined resultant flow may then have a flow profile with pulsation amplitudes that are smaller than the individual pump segment pulsation amplitudes.11-11-2010
20100286650Medical Fluid Container - A medical fluid container is disclosed that comprises a single reservoir of fluid impermeable material having a fluid impermeable barrier dividing the reservoir into at least first and second fluid-holding compartments. A valve is selectively movable to allow flow of fluid from the compartments. A method of dispensing medical fluids from a medical fluid container is also disclosed.11-11-2010
20110276024Treatment Fluid Delivery Method, And Turbulator For Promoting Uptake Of A Treatment Agent - A turbulator for promoting mixing of fluids passing through a body lumen includes an elongate flow perturbing component and an elongate shape controlling component freely slidable within the flow perturbing component. The turbulator is adjustable from a low profile, lumen access configuration to a deployed configuration via sliding the shape controlling component within the flow perturbing component. Adjusting the turbulator within a body lumen of a patient induces turbulence within a flow of fluid passing through the body lumen to increase mixing of a treatment fluid with the body fluid by way of the induced turbulence.11-10-2011
20110276023Apparatus and Methods for Accessing the Lymphatic System - Systems and methods are provided for performing a medical procedure within a patient's body that involves a thoracic duct including an ostium communicating with the patient's venous system. A distal end of a catheter is introduced through the patient's venous system into a body lumen adjacent the ostium of the thoracic duct. An expandable member on the distal end of the tubular may be expanded adjacent the ostium, e.g., within the body lumen or the thoracic duct itself, and used to isolate the thoracic duct from the body lumen, whereupon a medical procedure may be performed via the thoracic duct. For example, lymphatic fluid may be removed from the thoracic duct through a lumen of the tubular member and/or one or more agents may be introduced into the thoracic duct through the tubular member.11-10-2011
20110276022Catheter, Fluid Conveying Method, And Percutaneous Procedure - A catheter includes an elongate catheter body having an outer surface with a non-uniform contour and including a plurality of maximum surface elevation points and a plurality of minimum surface elevation points defining a non-uniform elevation profile relative to a longitudinal axis of the catheter body. The outer surface further includes a fluid transfer interface which includes the plurality of minimum surface elevation points and a plurality of porous surface areas, and a tissue contact interface which includes the plurality of maximum surface elevation points and a plurality of nonporous surface areas. The tissue contact interface inhibits external occlusion of the fluid transfer interface during transferring fluid between a fluid lumen defined by the elongate catheter body, and an intraluminal space such as an intravascular space within a patient.11-10-2011
20110238033DIABETES THERAPY DEVICE ENABLING SHIFTING OF PARAMETER PROFILES - A diabetes therapy device is disclosed herein, which includes a profile memory storing a parameter profile and a dedicated reference time mark. The parameter profile defines at least one parameter that is associated with insulin administration as a function of time for a generally circadian chronobiological cycle. The reference time mark indicates the beginning of the circadian chronobiological cycle and initializes a running time. Insulin amounts to be administered are determined as a function of the running time in accordance with a current matching of the parameter profile. A modified matching based on the reference time mark and an upcoming trigger time is computed and is time-shifted from the current matching, wherein the modified matching is applied by making the modified matching the current matching, such that future insulin amounts to be administered are determined in accordance with the modified matching.09-29-2011
20090177180USER INTERFACE IMPROVEMENTS FOR MEDICAL DEVICES - A method and system is disclosed for operating a medical device with or without a cassette in place. A method is disclosed for adding additional VTBI to an ongoing infusion without stopping the infusion and with maintaining the infusion parameters. A method and system is disclosed for changing the CCA without having to interrupt or completely stop an ongoing infusion. Quick titration buttons are provided to allow improved navigation between various delivery display screens.07-09-2009
20100292669METHOD AND APPARATUS FOR IN SITU DRUG DELIVERY DURING DISTRACTION OSTEOGENESIS - A device and technique for the performance of distraction osteogenesis of bone with controlled drug delivery using a bead chain consisting of two bands and a series of drug delivery capsules placed in a precise manner such that the relative motion of the bone segments brings the wires, pins, or screws into contact with the capsules and divides them. This action sequentially delivers the drug to the distraction zone throughout the distraction osteogenesis process.11-18-2010
20120259310Medicine Dispensing Device - Some embodiments of a wearable, disposable medicine dispensing device may include a piston rod that is advanced to dispense medicine from the device. A rotational motor may be coupled to a drive mechanism so as to carry out a certain number of revolutions and thereby displace the piston rod by a desired distance. Such a device can be used in a method of dispensing liquid medicine.10-11-2012
20120259309Kidney protection method - A method of driving a toxin through a patient's kidneys, the method includes administering a diuretic to the patient to induce increased urine flow and collecting urine expelled by the patient. The amount of urine expelled by the patient is determined based on the collected urine. The patient is infused with fluid from a fluid source. Diuresis is induced by automatically adjusting the amount of fluid infused into the patient from the fluid source based on the determined amount of urine expelled by the patient to at least balance the amount of urine expelled by the patient with the amount of fluid infused into the patient to drive the toxin out of the patient's kidneys.10-11-2012
20100318059ROBOTIC DEVICES WITH AGENT DELIVERY COMPONENTS AND RELATED METHODS - Various robotic devices and related medical procedures are disclosed herein. Each of the various robotic devices have an agent delivery component. The devices include mobile robotic devices and fixed base robotic devices as disclosed herein. The agent delivery component can have at least one agent reservoir and a discharge component in fluidic communication with the at least one reservoir.12-16-2010
20120283693Antiseptic Cap with Antiseptic - A syringe assembly including: (1) a syringe barrel defining a chamber; (2) a plunger mounted in the chamber and moveable with respect to the barrel; and (3) a cap assembly containing a cap and an absorbent material is removably attached to the plunger.11-08-2012
20120283692MESH BASED FLUID DELIVERY PROSTHESIS AND METHOD OF USE - A fluid delivery system is used for the treatment of subcutaneous hernia sites and includes a bioabsorbable polymer fabric mesh layer and a bioabsorbable and permeable bladder attached to the upper side of the fabric mesh layer. Fluid from the bladder is diffused through pores communicating between the bladder and the fabric mesh layer so as to be dispersed to underlying tissue.11-08-2012
20120283691AUTOMATED PRESSURE LIMIT SETTING METHOD AND APPARATUS - A method of infusing a fluid includes receiving values of one or more infusion parameters for an infusion of a fluid. Based on the received infusion parameter values, an occlusion pressure threshold for the infusion of the fluid is automatically calculated. During the infusion, a fluid pressure value is sensed. An indication is provided responsive to whether a value of the sensed fluid pressure is greater than the occlusion pressure threshold.11-08-2012
20130158501Device for the dosed dispensing of a fluidic medium - A device for the dosed dispensing of a medium (e.g., therapeutic and/or diagnostic agent) for an insulin pump is proposed. The device comprises a transporting and transferring container, a measuring element, and an adjusting element for influencing a dispensing of the medium by way of a connection to an interior space. The transporting and transferring container has a reservoir for receiving the medium. The reservoir is closed by a displaceable element. The displaceable element is movably mounted in relation to the reservoir. A relative positioning of the displaceable element in relation to the reservoir determines the interior space of the reservoir available for receiving the medium. The measuring element senses the relative positioning of the displaceable element in relation to the reservoir. The measuring element and the adjusting element interact so that the dispensing of the medium is influenced by the relative positioning sensed by the measuring element.06-20-2013
20110282318DEVICES, SYSTEMS AND RELATED METHODS FOR DELIVERY OF FLUID TO TISSUE - Described are devices useful to inject fluid to tissue without the use of a needle, and related methods; the devices include one or a combination of features such as ejection orifices (11-17-2011
20110282319Catheter and guide tube for intracerebral application - A catheter for use in neurosurgery, and a method of positioning neurosurgical apparatus. The catheter has a fine tube arranged for insertion into the brain parenchyma of a patient with an external diameter of not more than 1.0 mm. The catheter and method may be used in stereotactically targeting treatment of abnormalities of brain function, and for the infusion of therapeutic agents directly into the brain parenchyma. This is advantageous when a therapeutic agent would have widespread unwanted effects which could be avoided by confining the delivery to the malfunctioning or damaged brain tissue.11-17-2011
20130123743MEDICAL TUBING DETECTION AND MANAGEMENT - A system for medical tubing detection and management could include an infusion manifold housing having at least one fluid channel therethrough. At least one fluid input port could be provided in the infusion manifold housing and could be configured to connect fluidically to illuminated medical tubing and communicate with the at least one fluid channel through the infusion manifold housing. A fluid output port could be provided in the infusion manifold housing and be configured to be in fluidic communication with the at least one fluid channel through the infusion manifold housing. At least one photosensor could be provided in the infusion manifold housing and be configured to receive light from the illuminated medical tubing; and the fluid output port could be configured to connect fluidically to fluid output tubing.05-16-2013
20110295226DELIVERY DEVICE FOR DELIVERING BIOACTIVE AGENTS TO INTERNAL TISSUE IN A BODY - A device and method for administering a bioactive agent to internal tissue in a body, by introducing a balloon in a deflated condition into the body, inflating the balloon, introducing the bioactive agent into the balloon at the time of, after, or before the inflation of the balloon, and delivering the bioactive agent from the balloon to the tissue.12-01-2011
20110313393Implantable Device and Method for Delivering Drug Depots to a Site Beneath the Skin - An implantable device and method is provided for anchoring a drug depot to a site beneath the skin of a patient, the device and method comprising a head, a shaft and a tip, the head having a recess and/or at least one projection arranged to be engaged by an implantation tool, the shaft having an outer surface that engages the site in a manner that holds the device at the site beneath the skin, the head or shaft having means for attaching the drug depot thereto, and the tip disposed on the shaft opposite the head and capable of insertion into the site beneath the skin of the patient.12-22-2011
20110313392STEERABLE EPIDURAL CATHETER - A steerable catheter device which can be steered to locations within the epidural space, as well as methods of use and manufacture are disclosed. The steerable catheter provides a site-specific drug delivery system for accessing the epidural space. The catheter devices includes a steerable wire or a liner extending from a proximal end of the catheter to the catheter's distal end. Forces applied to the wire or the liner cause the distal end to deflect and/or rotate to reach a targeted epidural site.12-22-2011
20110313391Infusion set with anesthetic compound - An exemplary insulin infusion set that further provides one or more set elements including the hub, hub adhesive, fluid line tubeset, connectors, catheters and insertion needles which can be impregnated with, coated with, or otherwise configured to contain and administer an anesthetic at the insertion and set placement locations to minimize user discomfort and the risk of complications associated with the use of infusion sets. To do so, the system and method provides steps for mixing at a step (12-22-2011
20110313390METHOD AND/OR SYSTEM FOR CLOSED-LOOP CONTROL OF GLUCOSE TO A TREATMENT RANGE - Subject matter disclosed herein relates to monitoring and/or controlling blood glucose levels in patients. In particular, one or more substances may be delivered to a patient at a particular infusion rate while the patient's estimated glucose level is within a predetermined range. A different insulin infusion rate may then be applied if the patient's estimated blood glucose level deviates outside of the predetermined range.12-22-2011
20130190714MULTI-LAYERED TUBING - Tubing comprising an inner layer, an outer layer and a middle layer, wherein the inner layer comprises a polyethylene, the outer layer comprises a thermoplastic polyurethane and the middle layer comprises an ethylene ethyl acrylate copolymer or an ethylene methyl acrylate copolymer or an anhydride grafted ethylene methyl acrylate copolymer, a copolymer of two or more of the acrylate copolymers or a mixture of two or more thereof.07-25-2013
20120029468INFUSION PUMP SYSTEM WITH DISPOSABLE CARTRIDGE HAVING PRESSURE VENTING AND PRESSURE FEEDBACK - Embodiments are directed to portable infusion devices, systems, and methods of using the same for dispensing materials. In some cases, the devices, systems and methods may be used for infusing a material such as medicament, e.g., insulin, into a body in need thereof.02-02-2012
20120029467METHOD OF IMPLANTING A SPINAL CORD STIMULATOR LEAD FOR NEUROSTIMULATION HAVING A FLUID-DELIVERY LUMEN AND/OR A DISTENSIBLE BALLOON - A method of implanting a spinal cord stimulator lead in the epidural space of a human or animal subject. The method includes expanding a distensible balloon, which is positioned around a distal end of the shaft and in fluid communication with a lumen, to clear a tissue obstruction during the implantation. Preferably, the balloon expands radially outwardly from at least a portion of the shaft's distal end. The method can also include discharging a pressurized fluid, axially through a lumen in the spinal cord stimulator lead, directly to a tissue obstruction during the implantation.02-02-2012
20120029466DRAINAGE DEVICES AND METHODS FOR USE - Devices and methods for draining excess lymph fluid are disclosed. The device can be fixed to the blood vessel adjacent to the thoracic duct. The device can have a port for withdrawing lymph fluid exiting the thoracic duct. The device can have a cannula and/or subcutaneous port to draw the lymph fluid away from the thoracic duct and reduce hemostatic pressure in the lymphatic system.02-02-2012
20120029465Blunt Needle Safety Drug Delivery System - Drug delivery devices having non-luer connections and adapters and adaption connectors for providing non-luer connections to drug delivery devices are provided. An exemplary drug delivery device for use with a catheter connection includes a blunt needle component with a non-luer connection and a filter component with a non-luer connection, wherein the non-luer connections of the blunt needle component and filter component are incompatible with standard luer fitting and intravenous route-accessing devices. In one or more embodiments, an adapter having a non-luer connection at one end and a luer connector is provided for use with blunt needle components and filter components wherein one of the blunt needle component and the filter component includes a luer connection and the other of the blunt needle component and the filter component includes a non-luer connection. Methods of delivering liquid medication to a catheter are also provided.02-02-2012
20130197468Device for Intramyocardial Delivery - Methods and apparatuses for delivery of biologically active material and/or sensors to a target organ or system. The apparatuses allow for specific, controlled delivery of the biologically active material and targeted placement of sensors. The apparatuses may be fabricated from cellular and/or acellular biological active components to promote integration of sensors into tissue and achieve appropriate release of biologically active molecules. The apparatuses may be fabricated from plasma-containing materials or other biopolymers such that the apparatus will resorbed into the tissue following insertion. The biologically active cellular or acellular component may be incorporated into that material may then serve as the source of the therapeutic biologically active component. The apparatus may take the form of a screw, though numerous shapes arc contemplated. The delivery methods and apparatuses of the present invention may be employed in a wide variety of physiological and medical situations, with cardiac implementations being particularly appropriate.08-01-2013
20130197470Adaptable Perioperative Cell-Salvage System and Methods and Disposable Units for Same - A blood-collection system configured to permit selection of either collection and disposal of shed blood from a patient or collection and processing of shed blood for autologous transfusion back to the patient includes an automated blood-processing machine. The system may also include a blood-collection reservoir, a separation chamber, and a fluid conduit. The blood-collection reservoir may be engageable with the blood-processing machine so that the machine can identify and report the presence of blood in the reservoir. The separation chamber may also be engageable with the blood processing machine. The fluid conduit may be configured to selectively join the reservoir to the separation chamber by a quick-connect coupling.08-01-2013
20130197472Low Profile Instrument Immobilizer - This document discusses, among other things, examples of a low profile instrument immobilizer and means for positioning the same. In one example, the low profile instrument immobilizer grasps, secures, and immobilizes an electrode or other instrument that extends through a burr hole in a skull to a target location in a patient's brain.08-01-2013
20130197471FLUID MANAGEMENT SYSTEM - Fluid management system and method of operating a fluid management system which may provide one or more functions associated with suction, irrigation, distention, deficit monitoring, infusion, fluid warming, and the like. The fluid management system may be selectable between pressure control and flow control modes.08-01-2013
20120035582METHODS AND SYSTEMS FOR HANDLING OR DELIVERING MATERIALS FOR NATURAL ORIFICE SURGERY - The embodiments disclosed herein relate to various medical systems, including systems that can be used in conjunction with medical devices used in endoscopic surgery. Certain embodiments include various material handling devices that can transport materials between the inside and the outside of an endoscopic surgery patient.02-09-2012
20120035581Infusion Pump and Slide Clamp Apparatus and Method - An infusion pump for metering fluid flow through an delivery tube of an infusion tubing set has an internal occlusion clamp which clamps the delivery tube to prevent the free flow of fluid through the tube when access to the delivery tube in the infusion pump is possible. To release the delivery tube from the infusion pump, a slide clamp is manually used to release the occlusion clamp to an open, non-occluding position while simultaneously occluding the delivery tube to prevent the free flow of fluid.02-09-2012
20120046639MICROFLUIDIC FREE INTERFACE DIFFUSION TECHNIQUES - A static fluid and a second fluid are placed into contact along a microfluidic free interface and allowed to mix by diffusion without convective flow across the interface. In accordance with one embodiment of the present invention, the fluids are static and initially positioned on either side of a closed valve structure in a microfluidic channel having a width that is tightly constrained in at least one dimension. The valve is then opened, and no-slip layers at the sides of the microfluidic channel suppress convective mixing between the two fluids along the resulting interface. Applications for microfluidic free interfaces in accordance with embodiments of the present invention include, but are not limited to, protein crystallization studies, protein solubility studies, determination of properties of fluidics systems, and a variety of biological assays such as diffusive immunoassays, substrate turnover assays, and competitive binding assays.02-23-2012
20130102993LIPOSOME COMPRISING ELASTIN-LIKE POLYPEPTIDE AND TUMOR CELL TARGETING MATERIAL AND USE THEREOF - A liposome including an elastin-like polypeptide (ELP) and a tumor cell targeting material, a pharmaceutical composition including the liposome, and a method of delivering an active agent to a target site using the liposome.04-25-2013
20120059348Method and Apparatus For Setting A Basal Rate Profile For An Insulin Pump - Methods for setting a basal rate profile for an insulin pump, wherein the basal rate profile defines a basal rate delivery for a selected time interval and has a pre-defined number of profile segments each of which define the basal rate delivery for a subset of the selected time interval, include providing a curve representing the basal rate as a continuous function of time as an input for an input unit and generating the basal rate profile from the curve by a calculation unit by assigning curve values at selected time instances to the pre-defined number of profile segments.03-08-2012
20130204223ENDOSCOPIC SURGERY INSTRUMENTATION - An embodiment of the invention includes a quantum fluid flow management apparatus which controls and facilitates delivery of liquid and/or air to the surgical site during a surgical procedure via a trumpet valve, various restriction (crimping) devices, and a network of tubing for selectively passing air or fluid through to the surgical site. The trumpet valve allows for selective control of air or fluid or both or neither. Additionally the flow management apparatus controls the application and suction of fluids from the surgical site which may be used in cooperation with the injection of a fluid such as water to irrigate the surgical site to remove body fluids, debrided material or the like.08-08-2013
20120071853ENTERAL SYRINGE - The present invention is an enteral syringe that can include an elongated body having a hollow cavity therein and at least one vent extending from the hollow cavity to an outside surface of the syringe body. The elongated body can have a first non-circular cross-section. The enteral syringe can also have a plunger operable to selectively travel within the hollow cavity. The plunger can additionally have a second non-circular cross-section that substantially mirrors the first non-circular cross-section. The enteral syringe can additionally have at least one support feature for hanging the syringe from a support structure.03-22-2012
20130211370Medicine Delivery Device - The invention relates to an apparatus comprising a first piezoelectric actuator comprising a shaft, the first piezoelectric actuator being configured to generate a reciprocating movement of the shaft for rotating a piston at least unidirectionally; the piston comprising a stopper being configured to deliver a medicine from a medicine container; and a clutch in contact with the piston; the clutch being configured to translate the rotational movement of the piston into a translational movement of the piston in a forward direction for delivering the medicine from the medicine container; and the clutch being configured to enable a backward movement of the piston in case a force applied to the piston in a backward direction exceeds a predefined value. The invention further relates to a method for delivering medicine and enabling refilling of a medicine container of the apparatus.08-15-2013
20130211368MICROFABRICATED NANOPORE DEVICE FOR SUSTAINED RELEASE OF THERAPEUTIC AGENT - A drug delivery device that includes a capsule for implantation into the body; the capsule further includes a reservoir for containing a substance such as a therapeutic agent, at least one port for allowing the substance to diffuse from or otherwise exit the reservoir, and a nanopore membrane in communication with the capsule at or near the exit port for controlling the rate of diffusion of the substance from the exit port. The device also includes an optional screen for providing structural stability to the nanopore membrane and for keeping the pores of the nanopore membrane clear. One embodiment of the drug delivery device includes an osmotic engine internal to the device for creating fluid flow through the device.08-15-2013
20130211369ANTIBIOTIC DELIVERY SYSTEM AND METHOD FOR TREATING AN INFECTED SYNOVIAL JOINT DURING RE-IMPLANTATION OF AN ORTHOPEDIC PROSTHESIS - An antibiotic delivery system including an intramedullary stem that is adapted to be removably mounted into a medullary canal of a bone. The stem includes a body having an inlet adapted to be in fluid communication with a source of liquid-borne antibiotic and a plurality of outlets disposed along the stem. A channel extends between the inlet and the plurality of outlets for delivering a fluid-borne antibiotic from the inlet to the plurality of outlets so as to distribute the antibiotic along the medullary canal in a controlled fashion. A method of treating an infected joint during a two-stage re-implantation of an orthopedic implant is also disclosed.08-15-2013

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