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With means for cutting, scarifying, or vibrating (e.g., ultrasonic, etc.) tissue

Subclass of:

604 - Surgery

604019000 - MEANS FOR INTRODUCING OR REMOVING MATERIAL FROM BODY FOR THERAPEUTIC PURPOSES (E.G., MEDICATING, IRRIGATING, ASPIRATING, ETC.)

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DocumentTitleDate
20110201995Weighted Infusion Sleeve - An irrigation sleeve for a phacoemulsification needle is constructed with a non-uniform distribution of mass. When the sleeve is used with torsional phacoemulsification apparatus the sleeve adds to the eccentric motion of the needle, adding efficiency to the phacoemulsification process. In one embodiment, weights are implanted in the sleeve. In another embodiment the sleeve is molded with concentrations of sleeve material at selected locations in the sleeve.08-18-2011
20110208115Composition Comprising Gas-Filled Microcapsules For Ultrasound Mediated Delivery - Composition comprising gas filled microcapsules and a bioactive agent, useful for an ultrasound-mediated delivery of said bioactive agent. The microcapsules comprise a relatively stiff shell of polymeric or lipid material and have in particular a resistance to a mechanical index of at least 0.15, while the bioactive agent is substantially unbound to the shell of the microcapsules. The composition of the invention is particularly suitable for effectively delivering a genetic material into a cell, upon exposure of the composition to a level of acoustic pressure capable of destroying a portion of the microcapsules and releasing the gas contained therein.08-25-2011
20120172785CASSETTE PRISM FOR FLUID LEVEL DETECTION - A surgical cassette has rigid walls for collecting aspirated tissue and fluid and for operable communication with a fluid level detection system of a surgical console, in which the surgical cassette is placed. The surgical cassette has an interior volume, defined by the rigid walls, to hold the aspirated tissue and fluid. A plurality of prisms are formed on an interior of at least one rigid wall, at a location, such that the prisms are in operable communication with the fluid level detection system, when the surgical cassette is placed in the surgical console. An exterior of the rigid wall corresponding to the location of the plurality of prisms is coplanar with an exterior of the rigid wall not corresponding to the location of the plurality of prisms.07-05-2012
20110190690INDEPENDENT SURGICAL CENTER - A biological tissue cutting and fluid aspiration system provides a plurality of surgical instruments operable independent of an external control console. In some embodiments, each surgical instrument may include all sensors and controls directly applicable to the surgical instrument, and may be used independently. In some embodiments, instruments communicate status information to each other, and adjust operating parameters based on the communications.08-04-2011
20110196287METHODS OF USING ULTRASONICALLY POWERED SURGICAL INSTRUMENTS WITH ROTATABLE CUTTING IMPLEMENTS - In one general aspect, various embodiments are directed to methods for treating tissue within an aqueous environment. Various methods may include introducing a cutting implement of a surgical instrument into the aqueous environment. The cutting implement may have at least one cutting surface thereon and at least one ultrasonic portion thereon and be selectively rotatable within a hollow sheath. The methods may include rotating or rotatably oscillating the cutting implement within the hollow sheath for tissue cutting purposes. The cutting implement may also be retained in a position wherein the ultrasonic portion of the cutting implement may be applied to tissue and then have ultrasonic motion applied thereto.08-11-2011
20110196286ULTRASONICALLY POWERED SURGICAL INSTRUMENTS WITH ROTATING CUTTING IMPLEMENT - In one general aspect, various embodiments are directed to an ultrasonic surgical instrument that comprises a handpiece housing that rotatably supports an ultrasonic transducer assembly therein that may be selectively rotated by various motor configurations. Various slip ring arrangements are disclosed for supplying ultrasonic electrical signals and motor drive signals from a control system. Various forms of blade and cutting implements are disclosed for attachment to the ultrasonic transducer assembly such that such implements may be selectively rotatable within a hollow outer sheath. Vacuum may be applied to the cutting implement or through the outer sheath to draw tissue through an opening in the sheath and into contact with the cutting implement.08-11-2011
20130211316METHOD AND APPARATUS FOR TREATMENT OF INTRACRANIAL HEMORRHAGES - An ultrasound catheter with fluid delivery lumens, fluid evacuation lumens and a light source is used for the treatment of intracerebral hemorrhages. After the catheter is inserted into a blood clot in the brain, a lytic drug can be delivered to the blood clot via the fluid delivery lumens while applying ultrasonic energy to the treatment site. As the blood clot is dissolved, the liquefied blood clot can be removed by evacuation through the fluid evacuation lumens.08-15-2013
20130079702SURGICAL FLUID MANAGEMENT SYSTEMS AND METHODS - A surgical fluid management system delivers fluid for distending a uterine cavity to allow cutting and extraction of uterine fibroid tissue, polyps and other abnormal uterine tissue. The system comprises a fluid source, fluid deliver lines, one or more pumps, and a filter for re-circulating the distension fluid between the source and the uterine cavity. A controller can monitor fluid retention by the patient.03-28-2013
20100145259THROMBECTOMY AND SOFT DEBRIS REMOVAL DEVICE - A device suitable for removing material from a living being is provided, featuring an infusate pump, and an aspiration pump, both powered by a motor. The aspiration pump and infusate pump preferably feature a helical pumping mechanism, and operate at a high rate of rotation, thereby ensuring adequate pumping performance and flexibility. Additionally, a narrow crossing profile is maintained, ensuring that the device may reach more tortuous regions of the vasculature. In one embodiment, the system comprises a wire-guided mono-rail catheter with a working head mounted on a flexible portion of the catheter that can laterally displace away from the guide wire to facilitate thrombus removal. The working head may be operated to separate and move away from the guide wire to come within a closer proximity of the obstructive material to more effectively remove it from the vessel.06-10-2010
20100145258SYSTEMS AND METHODS FOR ELIMINATING POST-EXCITATION VIBRATION IN OPHTHALMIC SURGICAL HANDPIECES - A method of eliminating post-excitation vibration provided from a surgical handpiece to a patient's eye during ophthalmic surgery. The surgical handpiece includes an ultrasonic vibration structure for generating vibration and a needle for transmitting the vibration into the patients eye. The method includes exciting the ultrasonic vibration structure and thereby causing the needle to vibrate for emulsifying tissue in the patient's eye, ceasing the excitation of the crystal structure, and generating a brake signal to restrain the vibration of the needle, upon ceasing the excitation of the crystal structure, thereby reducing the vibration provided to the patient's eye after excitation of the crystal structure has ceased.06-10-2010
20090187135ULTRASONIC SYRINGE - The present invention relates to an ultrasonic syringe for delivery and withdrawal of fluids from a human and/or animal patient. The ultrasonic syringe apparatus comprises a generator, a movable ultrasound transducer, a barrel, an ultrasound transducer tip, a radiation surface, an orifice located at the front end of the barrel, and a syringe head. The apparatus may further comprise a channel, a valve located on the distal end of the channel, and an orifice within the side wall which enables fluids to be delivered into the barrel. Ultrasonic waves emitting from the radiation surface induce vibrations within the fluids, sonicating the fluids, thereby eliminating the pain and discomfort associated with receiving injections, reducing and/or eliminating the force required to administer the injection, decreasing delivery time of the fluids into the body, and delivering ultrasonic energy to the tissue via the sonicated fluids.07-23-2009
20080294089Dendritic Polymers for Use in Acoustically Mediated Intracellular Drug Delivery in vivo - Targeted therapeutic delivery systems comprising specially-designed nanocarriers for intracellular therapeutic delivery, mediated by acoustic energy, for use either in vivo or in vitro are detailed. Nanocarriers comprised substantially of dendritic biopolymers and other species and compounds; are used to treat a variety of diseases in humans and other species, such as cancer, opthalmological, pulmonary, urinary or other pathologies. Methods for preparing the targeted therapeutic delivery systems are also embodied, which comprise processing a solution comprising biopolymers or other species and components, with or without targeting moieties, adding said biopolymers and other compounds to a solution containing one or more therapeutic agents, stabilizing or not stabilizing said nanocarriers, adding one or more contrast agents, resulting in a targeted therapeutic delivery system. Preferred therapeutics for use with the present invention include nucleic acids, proteins, peptides, and other therapeutic macromolecules.11-27-2008
20090171267RHEOLYTIC THROMBECTOMY CATHETER WITH SELF-INFLATING PROXIMAL BALLOON WITH DRUG INFUSION CAPABILITIES - The present disclosure involves a rheolytic thrombectomy catheter with a self-inflating proximal balloon having drug infusion capabilities. A self-inflating balloon having a plurality of outflow orifices located about the peripheral circumference thereof is located proximal to an inflow gap or orifices and a fluid jet emanator and which balloon is inflated and expanded by internal operating pressures to uniformly space and position the outflow orifices of the self-inflating balloon in close proximity to or in intimate contact with the thrombus or walls of the blood vessel. Devices of the present disclosure can be used for the purposes of thrombectomies, embolectomies, thrombus or vessel dilation and for the delivery of drugs to a thrombus or vessel site.07-02-2009
20130041311METHODS, DEVICES, AND SYSTEMS FOR ON-DEMAND ULTRASOUND-TRIGGERED DRUG DELIVERY - Injectable or implantable drug delivery systems providing on-demand ultrasound-triggered drug release and methods for controlling the release of drug in a patient are provided herein. The on-demand drug delivery systems contain a drug depot and a drug encapsulated in an encapsulating material, where the encapsulating material is different from the depot. In the preferred embodiment, the depot also contains microbubbles that encapsulate one or more gases. The microbubbles enhance the drug release when ultrasound is applied compared to the same system in the absence of microbubbles. In a preferred embodiment, the drug delivery system, contains an encapsulating material, preferably liposomes, a drug to be delivered, microbubbles, and at least two hydrogel-forming precursor components. Following injection or implantation, the patient can control the time, location and dosage released by administering ultrasound.02-14-2013
20090156983RHEOLYTIC THROMBECTOMY CATHETER WITH SELF-INFLATING DISTAL BALLOON - The devices of the present disclosure are rheolytic thrombectomy catheters with a self-inflating distal balloon. A self-inflating balloon is located distal to an inflow gap or orifice and distal to a fluid jet emanator, which self-inflating balloon is inflated and expanded by the utilization of internal operating forces consisting of forwardly directed high velocity fluid jet streams and/or entrained thrombus particulate therein. The self-inflating balloon, when inflated, impinges on the wall of the blood vessel to isolate sections of the blood vessel distal and proximal to the inflated balloon in order to prevent flow of thrombus particulate, fluids and the like distal to the self-inflating balloon and to provide a stagnant nonflow region proximal to the self-inflating balloon. The devices of the present disclosure also provide for a uniform spacing of the catheter tube with respect to the thrombus and/or wall of the blood vessel.06-18-2009
20090156982Transdermal treatment device and method - A treatment device for treating a medical condition comprises a composition selected for its ability to treat the medical condition, the composition being formulated for transdermal delivery. A portable container is provided which comprises a body for accommodating the composition in a sealed arrangement, a frangible seal on the container which can be ruptured to enable discharge of the composition from the body, and an application component on the container for facilitating transdermal delivery of the composition.06-18-2009
20100106078METHOD OF CONTROLLING A RELEASE OF A MATERIAL CARRIED BY ULTRASOUND SENSITIVE PARTICLES - This invention relates to a method and an apparatus of controlling a release of a material carried by ultrasound sensitive particles, the release being caused by irradiating the ultrasound sensitive particles with an ultrasonic pulse having acoustic properties selected so as to interact with the ultrasound sensitive particles and thus causing the release of the material. The ultrasound sensitive particles comprise sub-groups of ultrasound sensitive particles, the ultrasound sensitive particles within the same sub-group having their respective acoustic property causing each respective sub-group to interact independently with the sound wave.04-29-2010
20090124960Monitoring Thermal Conditions To Vary Operation of an Ultrasonic Needle Tip of a Surgical Instrument - A method and apparatus to operate a surgical instrument in response to a thermal condition being detected that warrants curtailment of further operation. When the thermal condition is reached, command signals are generated that cause a needle of the surgical instrument to either have its vibrational speed slowed, have its vibrational movement stopped, or have it withdrawn from its relative position. The detection is of infrared radiation wavelengths and is carried out with either a thermal imaging device of a thermal recognition device. A corresponding temperature of the detected infrared radiation wavelengths is compared to a critical temperature to determine whether the thermal condition has been reached.05-14-2009
20090124959DEVICE FOR TRANSDERMAL DRUG DELIVERY AND METHOD OF OPERATING SUCH A DEVICE - The present invention relates to a device (05-14-2009
20120184896CATHETER ACCESS AND CONTROL DEVICE AND METHOD OF USING SAME - The present application discloses a handle configured to receive a catheter. The handle comprises a port that communicates with a lumen of the catheter and a mechanism is provided that moves the end of the catheter for positioning. The guide wire traverses a reservoir located in the handle. In particular, the handle comprises an enclosure with a conduit and a reservoir, where the conduit extends through the enclosure from the left side to the right side and the reservoir space has a curved or concave base. The bottom side and top side of the handle converge into a tapered point on the left side.07-19-2012
20130046231COATING FORMULATIONS FOR SCORING OR CUTTING BALLOON CATHETERS - The present invention is related to scoring or cutting balloon catheters carrying at least on a portion of their surface at least one oxidation-insensitive drug or oxidation-insensitive polymer-free drug preparation and at least one lipophilic antioxidant at a ratio of 3-100% by weight of the at least one lipophilic antioxidant in relation to 100% by weight of the drug, wherein the at least one oxidation-insensitive drug is selected of taxanes, thalidomide, statins, corticoids and lipophilic derivatives of corticoids, and the at least one lipophilic antioxidant is selected of nordihydroguaiaretic acid, resveratrol and propyl gallate.02-21-2013
20130046230ULTRASOUND-ASSISTED CONVECTION ENHANCED DELIVERY OF COMPOUNDS IN VIVO WITH A TRANSDUCER CANNULA ASSEMBLY - A method for convection-enhanced delivery (CED) of compounds and an apparatus for use with the method are provided. The apparatus, an ultrasound transducer cannula assembly (TCA) apparatus, can be used for the delivery of a compound to a target in the body such as a cells, tissue or organ in a healthy or diseased state. The ultrasound TCA apparatus comprises a transducer cannula assembly (TCA) and an ultrasound system to enhance penetration of molecules in the target. The ultrasound system may be portable and pocket-sized. The inclusion of ultrasound in the apparatus improves the distribution volume of material four to six times over a convection-enhanced delivery system without ultrasound. Since the targeting can be more focused, less compound is needed, thus lowering the potential for harmful effects to the host and host cells.02-21-2013
20130046228Stacked Multi-Disk Ophthalmic Pump - The present disclosure relates to a stacked multi-disk pump for the pumping of ocular fluid and/or tissue during ophthalmic surgery. The stacked multi-disk pump includes an inlet port, a stacked multi-disk assembly, a fluid chamber, a central hub, a motor, and an outlet port. The motor and the hub induce the multi-disk assembly to rotate. As the multi-disk assembly rotates, the fluid is propelled into the inlet port, progresses axially, circumferentially, and radially through the stacked multi-disk assembly, and flows out the outlet port. The pump may be incorporated, for example, into the handpiece of an ophthalmic surgical instrument or a surgical console.02-21-2013
20130046229SYSTEMS AND METHODS FOR OPENING OF A TISSUE BARRIER - Systems and methods for opening a tissue to a target value using microbubbles are disclosed herein. In an embodiment of a method for opening a tissue to a target value using microbubbles, a region of the tissue is targeted for opening, an acoustic parameter corresponding to the target value is determined, and an ultrasound beam is applied to the target region at the acoustic parameter such that the tissue at the target region is opened to the target value with the microbubbles. The acoustic parameter can be selected to control an acoustic cavitation event and, in some embodiments, controlling an acoustic cavitation event can include controlling a location, number and/or magnitude of acoustic cavitation events.02-21-2013
20090043248Removable multi-channel applicator nozzle - The invention provides a multi-channel applicator nozzle.02-12-2009
20090312691MICRO NEEDLE ROLLER ASSEMBLY - The present invention provides a micro needle roller assembly comprising a roller head including an external cylindrical member having a plurality of micro needles mounted on a surface thereof and an internal member placed in the external member and supported to the external member by supporting piece; and a handling member coupled to the internal member for rotating the internal member of the roller head; the micro needles, the external cylindrical member and the internal member being made of polymer resin.12-17-2009
20110009808Multi needle apparatus for treating total volume of skin lesions by intralesional injection method - Viral warts are penetrated with a multiple solid needle apparatus which applies a bleomycin medication to the total volume of the wart. The disclosed method and apparatus provides a one step or two step procedure to quickly and efficiently penetrate all parts of a wart and evenly apply the bleomycin into the wart. Multiple solid needles are uniformly and symmetrically spaced and secured within a base unit. A syringe is used to press the base unit into a wart as well to deliver the bleomycin solution.01-13-2011
20090306583Method of Operating An Ultrasound Handpiece - A method of operating an ultrasonic handpiece by pulsing the power supplied to the handpiece and varying the type of vibration during the power pulse.12-10-2009
20090306582SCORING CATHETER AND METHOD FOR TREATING DISEASED HEART VALVES - The present invention provides a valvuloplasty catheter which has a scoring element at its distal part to score stenotic, calcified heart valves in radial direction and to make the single valve flaps/leaflets work again. In addition to this, the device could comprise an attached balloon to post-dilate the valve after the scoring procedure. To reduce a future recalcification, the scoring element and/or the balloon have a pharmacologic coating on their outer surface.12-10-2009
20090306580Wound treatment apparatus and method - An apparatus for cleansing wounds in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are moved by a device (which may be a single pump or two pumps) for moving fluid through a flow path which passes through the dressing and a means for providing simultaneous aspiration and irrigation of the wound. The apparatus also comprises means to apply high frequency vibrational energy, e.g. ultrasound, to the wound bed. The former removes materials deleterious to wound healing, while distributing materials that are beneficial in promoting wound healing over the wound bed. The latter promotes healing. The dressing and a method of treatment using the apparatus.12-10-2009
20090306581CONTROLLING A PHACOEMULSIFICATION SYSTEM BASED ON REAL-TIME ANALYSIS OF IMAGE DATA - A design for dynamically adjusting parameters applied to a surgical instrument, such as an ocular surgical instrument, is presented. The method includes detecting surgical events from image data collected by a surgical microscope focused on an ocular surgical procedure, establishing a desired response for each detected surgical event, delivering the desired response to the ocular surgical instrument as a set of software instructions, and altering the surgical procedure based on the desired response received as the set of software instructions.12-10-2009
20090093750PROBE TIP AND INFUSION SLEEVE FOR USE WITH OPHTHALMOLOGICAL SURGERY - A phacoemulsification probe includes a first portion for interconnecting the probe with a phacoemulsification machine. A probe tip has a first end connected with the first portion and a second end curved up to a predetermined angle. The probe tip defines a channel therein for aspirating material through the probe tip from a surgical region.04-09-2009
20130072857MEDICAL TOOL FOR REDUCED PENETRATION FORCE WITH FEEDBACK MEANS - A medical device for reducing the force necessary to penetrate living being tissue using a variety of reciprocating motion actuators, including piezoelectric, voice coil, solenoids, pneumatics or fluidics. The reciprocating actuator drives a penetrating member, such as a needle, through the tissue at a reduced force while the device detects the passage of the penetrating member through the tissue. Upon passage of the penetrating member through the tissue, electrical power to the reciprocating actuator is automatically terminated. One exemplary method for detecting this passage is via a fluid-containing syringe that is coupled to a channel within the penetrating member. Once the penetrating member tip has passed through the living tissue, the fluid within the syringe no longer experiences any pressure and a plunger within the syringe displaces indicating passage of the penetrating member tip. This motion can provide direct tactile feedback to an operator of the medical device or can automatically open a switch providing electrical power to the medical device. Alternatively, a pressure transducer can also monitor the pressure within the penetrating member channel and automatically activate the switch to cut off the electrical power.03-21-2013
20130072855APPARATUS FOR TREATING AN ORGAN AND RELATED METHODS OF USE - Embodiments of the disclosure may include a method of treatment. The method of treatment may include advancing a medical device to a wall of an organ having a plurality of layers of tissue. The medical device may include an elongate tube having a proximal end and a distal end, a lumen extending therebetween, and an injector disposed within the lumen. The injector may be configured to deliver a substance to a location between first and second layers of tissue of the plurality of layers of tissue within the organ wall. In addition, the method may further include delivering the substance to the location, wherein, when delivered, the substance is configured to spatially separate a portion of the first and second layers of the tissue.03-21-2013
20130072856MEDICAL TOOL FOR REDUCED PENETRATION FORCE WITH FEEDBACK MEANS - A medical device for reducing the force necessary to penetrate living being tissue using a variety of reciprocating motion actuators, including piezoelectric, voice coil, solenoids, pneumatics or fluidics. The reciprocating actuator drives a penetrating member, such as a needle, through the tissue at a reduced force while the device detects the passage of the penetrating member through the tissue. Upon passage of the penetrating member through the tissue, electrical power to the reciprocating actuator is automatically terminated. One exemplary method for detecting this passage is via a fluid-containing syringe that is coupled to a channel within the penetrating member. Once the penetrating member tip has passed through the living tissue, the fluid within the syringe no longer experiences any pressure and a plunger within the syringe displaces indicating passage of the penetrating member tip. This motion can provide direct tactile feedback to an operator of the medical device or can automatically open a switch providing electrical power to the medical device. Alternatively, a pressure transducer can also monitor the pressure within the penetrating member channel and automatically activate the switch to cut off the electrical power.03-21-2013
20130072854MICROBUBBLE COMPLEXES AND METHODS OF USE - The present invention relates to a microbubble complex comprising a microbubble having an outer shell comprising a mixture of native and denatured albumin encapsulating a perfluorocarbon gas, a therapeutic agent, a bifunctional linker having one end attached to the therapeutic agent and the other attached to a ligand and wherein the ligand is bound to the other shell of the microbubble through hydrophobic interactions. Also included are methods for delivering the aforementioned microbubble complex to a tissue target.03-21-2013
20130072853SYSTEMS AND METHODS FOR CONTROLLING VACUUM WITHIN PHACOEMULSIFICATION SYSTEMS - The invention relates to systems and methods for controlling vacuum within phacoemulsification systems. The phacoemulsification system may include a handpiece having a needle. The needle is coupled to a power source configured to cause the needle to be ultrasonically vibrated during operation and an aspiration source. The system further includes a footpedal that defines a first position and a second position. The system also includes a computer program product operatively coupled to the handpiece and the footpedal, the computer program product having a computer-usable medium having a sequence of instructions which, when executed by a processor, causes said processor to execute a process that controls power from the power source and vacuum from the aspiration source applied to the handpiece. The process includes the steps of providing a vacuum at a first level to the handpiece when the footpedal is at the first position; providing power to the handpiece when the footpedal is at the second position; and reducing the vacuum to a second level when the footpedal transitions from the first position to the second position.03-21-2013
20090192440Shaped Phacoemulsification Needle Tips - Phacoemulsification needle tips have indentations formed thereon to allow the needles to be used with torsional motion phaco handpieces and with phaco handpieces producing linear or longitudinal motion.07-30-2009
20110015564Direct Stream Hydrodynamic Catheter System - A direct stream hydrodynamic catheter system is provided for the removal of thrombus, lesions and the like including provisions for the infusion of drugs, lysing fluids and the like into a blood vessel. Physician controlled high powered direct fluid jet streams emanate from a fluid jet emanator in the form of robust radially directed fluid jet streams to impinge upon and ablate difficult and strong thrombus or lesions within a blood vessel. Effluent aspiration is controlled by an exhaust regulator in the form of a roller pump, but effluent removal can be assistingly influenced by the fluid pressure associated with the radially directed fluid jet streams.01-20-2011
20110015563Method Of Controlling A Surgical System Based On A Rate Of Change Of An Operating Parameter - A surgical system that is able to sense the onset of an occlusion or other surgical event as well as when an occlusion breaks. To help avoid overheating of the tip, the system of the present invention predicts the temperature of the eye using irrigation flow rate and reduces the power to the handpiece automatically if an overheating situation is predicted. Alternatively or in addition, the system of the present invention monitors the power drawn by the handpiece, which is indicative of the cutting load on the tip, and automatically adjusts the power or stroke of the tip to compensate for increased loads on the tip.01-20-2011
20110015562Composite Irrigation/Aspiration Needle With Ball Tip - An irrigation/aspiration needle has a rigid needle body over which an elastomeric sleeve is fitted. The elastomeric sleeve terminates in a smooth, relatively soft, rounded tip through which a passageway extends, communicating with a passageway in the sleeve which, in turn, communicates with passageways in the needle body and needle mount, forming a liquid flow path through the needle. The softness of the elastomeric sleeve and, particularly, the sleeve tip protects delicate eye tissue when the needle is used for aspiration from or irrigation of the eye during surgery.01-20-2011
20110015561Phacoemulsification Needle - A phacoemulsification needle having a hollow passageway terminates in a straight needle tip formed off-axis from the passageway, allowing the needle tip to move eccentrically when the needle is subjected to torsional or longitudinal vibratory motion. The tip may be flared or may be coextensive with the needle body. The aspiration passageway formed through the needle body may be formed off-axis from the needle body axis. The tip may also be angled with respect to the needle body. The inner and outer surfaces of the needle tip are roughened, as by sandblasting, to enhance the cutting effect of the tip when used with a non-longitudinal handpiece. The lip of each needle tip is polished to a high degree of smoothness and the edges of the tip are rounded to lessen the incidence of snags or cuts.01-20-2011
20090287142ULTRASONIC TREATMENT APPARATUS - There is provided an ultrasonic treatment apparatus, which may treat a part of the body to be treated without use of a medical agent. The ultrasonic treatment apparatus comprises a treatment vessel (11-19-2009
20090270793Priming a Microsurgical System - A microsurgical system capable of priming its aspiration circuit using a pressurized gas source, a pressurized infusion fluid source, an aspiration chamber fluidly coupled to the pressurized gas source and the pressurized infusion fluid source, and a computer.10-29-2009
20090270792MICROPROTRUSION ARRAYS AND METHODS FOR USING SAME TO DELIVER SUBSTANCES INTO TISSUE - Improved microprotrusion abrasion devices having fluid retaining or directing patterns, and specific design parameters and method for delivery of substances into the skin. Various configurations of such devices are disclosed, including domed, channeled, patterned and stepped.10-29-2009
20090270791Benign prostatic hyperplasia surgical system featuring mechanical coring probe with live aspiration - The invention comprises an atherectomy probe for mechanically cutting core prostatic tissue to alleviate the condition of benign prostatic hyperplasia (BPH) or for use in orthopedic procedures. The blade shapes and lengths are adaptable but in a preferred embodiment the device includes an end-cutting bur tip. The cutting motion may be one of: guillotine (incising between two parallel edges), radial reciprocating (changing radial directions and cuts between two horizontal edges), circular (continuously radial in one direction), and end-cutting, etc. The power source used to drive the blade may be one of: pneumatic, hydraulic, manual mechanical, electrical, solar, etc. The probe also includes several channels that may be used for providing live aspiration and removal of severed tissue and fluids, as well as insufflation of gases and optionally, pharmaceuticals and/or a secondary therapy. The instrument is designed for use in open, endoscopic, and minimally invasive transurethral or transperineal surgical procedures.10-29-2009
20090270790Device, methods, and control for sonic guidance of molecules and other material utilizing time-reversal acoustics - Acoustic waves exhibit a a streaming force that pushes objects along the direction of sound propagation. Precise motions require well-focused beams. The technique of time-reversal acoustics (TRA) overcomes beam distortions introduced by propagation along irregular paths to focus sound without knowledge of the medium properties. TRA requires a small receiver to be placed at a point of desired focus. The invention disclosed refines TRA by introducing data matching schemes to extend the points of focus beyond the location points of the receivers. With as few as two receivers, a large region can be manipulated with well-focused acoustic beams and with no receiver at a desired point of focus. Applications are described in drug delivery in medicine; environmental fluid contaminant control; and in oil exploration, for retrieving oil stuck in underground pockets.10-29-2009
20090270789SUCTION DOME FOR ATRAUMATICALLY GRASPING OR MANIPULATING TISSUE - The present invention provides a suction dome for atraumatically grasping, manipulating, and/or extracting tissues. The suction dome may be used with a surgical instrument having a suction channel. Such instruments include, for example: forceps, laparoscopes, endoscopes, bronchoscopes, and catheters. The suction dome comprises an outer wall non-permeable membrane and a tissue-engaging permeable membrane base. The non-permeable membrane may be supported by a plurality of expanding arms and defines a chamber in communication with the suction channel of the instrument.10-29-2009
20130066257Design of Interventional Cutting Balloon with Enhanced API Delivery Capability - A medical balloon assembly including an inflatable balloon and at least one cutting element extending from the balloon is disclosed. The inflatable balloon includes an outer wall facing outward and an inner wall facing outward. The cutting element comprises a plurality of openings therein including a first opening and a second opening. The first opening is closed off by a portion of the outer wall. The cutting element further includes a passageway extending from the first opening to the second opening. The passageway is defined by the cutting element and the portion of the outer wall which closes off the passageway. The passageway may contain a therapeutic agent.03-14-2013
20110021975Devices and methods for minimally invasive access to sinuses and treatment of sinusitis - The present invention provides minimally invasive devices and methods for accessing the sinuses and their surrounding structures for surgery and other treatments. The anterior ethmoid and maxillary sinuses are accessed and treated under minimal anesthesia with little or no postoperative limitation of activity or adverse symptoms. Direct visual verification of the sinuses and their natural ostia is utilized. Other paranasal sinuses may be treated by this method as well. The sinuses, in particular the maxillary and anterior ethmoid, are accessed via a direct anterior to posterior axis and the natural ostia of those sinuses is directly visualized for placement of a guide-free dilator, in the desired location within the natural ostia. That access to the maxillary ostium is accomplished by the anterior transuncinate “keyhole” approach in which a hole is punched in the uncinate process with the described devices according to the described methods. The properly placed dilator is expanded to allow drainage of the inflamed sinus and then withdrawn. An analogous ethmoid bulla “keyhole” approach and subsequent dilation are used for the anterior ethmoid sinus ostia. Pharmaceutical agents may be placed at desired locations in the sinuses using the same access technique.01-27-2011
20130102955APPARATUS AND METHOD FOR PERFORMING PHACOEMULSIFICATION - An apparatus provides mechanical energy to vibrate a tip. The tip preferably formed of multiple prongs positioned approximately circumferentially (either symmetrically or asymmetrically) around an orifice. The tip is designed to emulsify a cataractous lens and to collect the resulting detritus through an aspiration aperture. An irrigating aperture is provided at a point spaced away from the tip and forms a plume or river of irrigating fluid that less directly confronts lens detritus at the needle tip and therefore collects this detritus in a more efficient and salutary manner as it flows to the aspiration aperture, said plume extend around the prongs. The prongs can be driven at either subsonic frequencies or ultrasonic frequencies.04-25-2013
20090254020ULTRASONIC METHOD FOR ESTABLISHING AND MAINTAINING A LIQUID SUSPENSION DELIVERY SYSTEM THAT PREVENTS THE DISPERSED PARTICLES FROM PRECIPITATING OUT OF SUSPENSION - The present invention relates generally to a method and apparatus for applying wave energy of an ultrasonic frequency to agitate particles in a sample. The agitated sample is then delivered via a syringe or a resonating syringe plunger attachment of an applicator. More particularly, the present invention relates to establishing and maintaining a liquid suspension delivery system that prevents dispersed particles from precipitating out of suspension while the sample is delivered through to various applicators, such as resonating syringe plungers.10-08-2009
20090247937METHOD AND APPARATUS FOR THE ULTRASONIC CLEANING OF BIOFILM COATED SURFACES - To treat body surfaces, such as the sinuses, which are coated with biofilms, the surface is irrigated and suctioned with a fluid which may contain a biocide or other chemical agent for disrupting the biofilm while ultrasonic energy is applied to either the fluid barrier formed over the biofilm or a body surface proximal to the biofilm. Action of the fluid enhanced by the ultrasonic energy tends to remove sections of biofilm which are suctioned out of the site. An electrical field may also be applied to the biofilm to enhance the disruptive action. Apparatus for practicing this method to treat chronic rhinosinusitis comprises an elongated tube adapted to be inserted into sinus cavities through the nose or mouth. The tube includes a first lumen which feeds an irrigating fluid containing biocides and/or biofilm-disruptive chemicals to the treatment site and a second lumen which suctions fluid from the site. An ultrasound horn extends through the tube and its distal end introduces ultrasonic energy into the fluid layer overlying the biofilm. Alternatively, an ultrasound probe may be applied to an adjacent body surface, such as the face over a sinus cavity. In an alternative embodiment, the tube includes a pair of electrodes which establish an electric field across the biofilm, accelerating degradation.10-01-2009
20120116290GILLED PHACOEMULSIFICATION IRRIGATION SLEEVE - A phacoemulsification irrigation sleeve includes an elongated, resilient, tubular body section configured to surround a portion of a shaft of a phacoemulsification needle, the tubular body section having a distal end and a proximal end, and an inner surface and an outer surface. An enlarged section formed on the proximal end of the tubular body portion surrounds a hub of the phacoemulsification needle and connects the irrigation sleeve to a phacoemulsification handpiece. The irrigation sleeve further comprises at least one slitted irrigation port formed adjacent to the distal end of the body section and configured to splay in response to a drop in pressure between the inner surface and the outer surface.05-10-2012
20120116289SHOCKWAVE VALVULOPLASTY DEVICE WITH GUIDEWIRE AND DEBRIS BASKET - A valvuloplasty system comprises a balloon adapted to be placed adjacent leaflets of a valve. The balloon is inflatable with a liquid. The system further includes a shock wave generator within the balloon that produces shock waves. The shock waves propagate through the liquid and impinge upon the valve to decalcify and open the valve. The balloon is carried on a catheter that includes a guidewire lumen. The system further includes a debris collecting basket carried on the catheter proximal to the balloon.05-10-2012
20090234274Retractable Tip For Vitrectomy tool - A probe for a vitrectomy tool is provided having a vitreous cutter tube having a blunt tip at a distal end and adapted to be coupled at a proximal end to a handpiece of a vitrectomy tool; a retractable outer trocar tube surrounding the vitreous cutter tube having an open distal end with a sharpened edge; and a retraction mechanism coupled to a proximal end of the outer trocar for selectively extending and retracting the outer trocar tube between a first extended position wherein the sharpened edge of the outer trocar is extended beyond the blunt tip of the vitreous cutter tube to facilitate insertion into the eye and a second retracted position wherein the sharpened edge of the outer trocar is retracted behind the blunt tip of the vitreous cutter tube to facilitate safe operation of the probe. A vitrectomy tool for removing material from an eye of a patient is provided having a housing having a proximal end and a distal end and a probe coupled to the proximal end of the housing.09-17-2009
20080294088Biodegradable Tissue Cutting Device, A Kit And A Method For Treatment Of Disorders In The Heart Rhythm Regulation System - A tissue cutting device is disclosed, which is structured and arranged to be inserted through the vascular system into a body vessel adjacent to the heart and/or into the heart, and to be subsequently subjected to a change of shape in order to penetrate into the heart tissue. The tissue cutting device may thus be used for treating disorders to the heart rhythm regulation system. A kit of tissue cutting devices provides a plurality of devices for creating a lesion pattern for treating such disorders. The tissue cutting device is of a biodegradable material, such as hydrolytically degradable material or an enzymatically degradable material.11-27-2008
20080294087Systems and Methods for Transverse Phacoemulisification - The invention is generally directed to phacoemulsification systems and methods, and more particularly to systems and methods for providing transverse phacoemulsification. In accordance with one embodiment, a phacoemulsification system is provided having a handpiece with a needle, wherein the phacoemulsification system is configured to vibrate the distal end of the needle in both an effective transverse direction and an effective longitudinal direction when power, having a single effective operating frequency is applied to the handpiece.11-27-2008
20110028887WATER JET SURGICAL INSTRUMENT - A water jet surgical instrument including a supply line for supplying a cutting fluid and a discharge nozzle for forming and discharging a fluid jet, wherein the fluid jet has a predetermined spread angle and/or a predetermined emergence energy. A jet shaping device is arranged relative to the discharge nozzle such that the fluid jet is able to be adjusted by the jet shaping device with regard to the spread angle and/or emergence energy thereof.02-03-2011
20120232465ULTRASOUND CATHETER AND METHODS FOR MAKING AND USING SAME - Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and, in some embodiments, a guidewire tube extending through the lumen. A distal head for disrupting occlusions is coupled with the distal end of the ultrasound transmission member and is positioned adjacent the distal end of the catheter body. Some embodiments include improved features such as a bend in the catheter body for enhancing positioning and/or advancement of the catheter.09-13-2012
20110282272CRYOTREATMENT DEVICE AND METHOD - Devices and methods for cooling vessel walls to inhibit restenosis in conjunction with medical procedures such as coronary artery angioplasty. Stenosed vessel walls can be cooled prior to angioplasty, after angioplasty, or both. The invention is believed to inhibit restenosis through cooling to a temperature near freezing, preferably without causing substantial vessel wall cell death. One catheter device includes a distal tube region having coolant delivery holes radially and longitudinally distributed along the distal region. In some devices, holes spray coolant directly onto the vessel walls, with the coolant absorbed into the blood stream. In other embodiments, a balloon or envelope is interposed between the coolant and the vessel walls and the coolant returned out of the catheter through a coolant return lumen. Some direct spray devices include an occlusion device to restrict blood flow past the region being cooled. Pressure, temperature, and ultrasonic probes are included in some cooling catheters. Pressure control valves are included in some devices to regulate balloon interior pressure within acceptable limits. In applications using liquid carbon dioxide as coolant, the balloon interior pressure can be maintained above the triple point of carbon dioxide to inhibit dry ice formation. Some cooling catheters are coiled perfusion catheters supporting longer cooling periods by allowing perfusing blood flow simultaneously with vessel wall cooling. One coiled catheter is biased to assume a coiled shape when unconstrained and can be introduced into the body in a relatively straight shape, having a stiffening wire inserted through the coil strands.11-17-2011
20110282271INFILTRATION CANNULA - An infiltration cannula and method of using the infiltration cannula during an infiltration procedure are disclosed herein. The infiltration cannula has a flexible cannula and a hub. The cannula has a proximal end and a distal end. The cannula also has a plurality of apertures disposed in a pattern about the distal end. The apertures are configured to infiltrate fluid into the subcutaneous or muscle tissue of a patient. The hub is configured to be held by a person performing the infiltration procedure. The hub has a first end and an opposing second end. The first end is attached to the proximal end of the flexible cannula and the second end includes a connector configured to connect to an input source for receiving the fluid to be infiltrated into the subcutaneous tissue of the patient. The fluid flows from the connector, through the hub and into the cannula.11-17-2011
20080319375Materials, Methods, and Systems for Cavitation-mediated Ultrasonic Drug Delivery in vivo - Materials, methods, and systems for targeted and non-targeted therapeutic delivery in vivo utilizing cavitation-mediated ultrasonic drug delivery are described. Noninvasive sonic energy being applied to the patient in a controlled fashion at the treatment area results in controlled acoustic cavitation at said region, and cell and tissue specific drug delivery. Microbubbles, both in the form of contrast agents, and/or other active agents infused into the patient, and/or bubbles formed from previous ultrasound exposure, allow for predictable cavitation thresholds, requiring much lower incident ultrasound intensities for permeating tissue. Further, methods and systems are provided that result in more spatially regular areas of controlled tissue permeability upon treatment, limiting cytotoxicity and sonolysis, and maximizing intracellular drug delivery. Moreover, by using pulsed cavitation-mediated ultrasonic drug delivery as described by the present teachings, a large number of parameters are created, which provided the appropriate monitoring and feedback mechanisms are present, allow the use of a diversity of parameter optimizations and control systems for customizing the methods and systems for a given application. Preferred therapeutics for use with the present invention include nucleic acids, proteins, peptides, and other therapeutic macromolecules.12-25-2008
20110034860MICRO-NEEDLE ARRAY AND METHOD OF USE THEREOF - A micro-needle array is provided that may be used to deliver a bioactive agent to a therapeutic target. The micro-needle array preferably includes a substrate, a plurality of micro-needles integral with the substrate, and a bioactive agent. At least one micro-needle preferably includes a top surface, a bottom surface, a side surface, and a cavity defined by an inner surface. The bioactive agent may be disposed on the substrate and the plurality of micro-needles. The at least one micro-needle may further include a slit connecting the cavity to an aperture, the slit extending from the top surface to the bottom surface.02-10-2011
20110137235ULTRASONIC CANCER THERAPY ACCELERATOR - Provided is an ultrasonic cancer therapy accelerator comprising titanium oxide-metal complex particles showing a long-lasting antitumor effect imparted thereto while sustaining the dispersibility and catalytic activity thereof which are obtained by dispersing titanium oxide-metal complex particles in an aqueous solvent with the use of a water-soluble polymer and modifying the same with molecules containing a low-valent transition metal via linker molecules having been bound thereto without denaturing the water-soluble polymer. To the titanium oxide surface of titanium oxide-metal complex particles which have been dispersed in an aqueous solvent with the use of a water-soluble polymer, linker molecules are bound via at least one functional group selected from the group consisting of carboxyl, amino, diol, salicylate and phosphate groups followed by the modification with low-valent transition metal-containing molecules via the linker molecules. Thus, an ultrasonic cancer therapy accelerator, which comprises titanium oxide-metal complex particles showing a long-lasting antitumor effect imparted thereto while sustaining the dispersibility and catalytic activity thereof, can be provided. This ultrasonic cancer therapy accelerator, which accumulates in an affected area, can be used as a drug for therapy combined with ultrasonic irradiation.06-09-2011
20090062724SYSTEM AND APPARATUS FOR SONODYNAMIC THERAPY - The present invention relates to diffuse ultrasound along with chemical agents to treat tissue, called sonodynamic therapy (SDT), and a system for treatment using SDT that comprises a whole body ensonification apparatus and control system. The whole body ensonification may reduce the chances of missing desired tissue that may not be easily detectable or may be found throughout the body. The apparatus has a plurality of diffuse ultrasound transducers for ensonifying at least part of a chamber filled with fluid and designed to accommodate a body for treatment. The person may be treated with sono-sensitive chemical agents, which may be activated when ensonified by the apparatus.03-05-2009
20100249693CASSETTE CAPTURE MECHANISM - The present invention pertains to a cassette capture mechanism for uniting a cassette with a console to prevent jamming or damage to the console and/or cassette. The cassette capture mechanism comprises a cassette receptacle, an axial translation linkage, a first sensor apparatus, and a second sensor apparatus. The cassette receptacle is configured to couple with a cassette having a positioning surface. The axial translation linkage is configured to couple the cassette with the cassette receptacle. The first sensor apparatus is configured to detect alignment of the cassette in a horizontal plane with respect to the cassette receptacle when the cassette is initially coupled with the cassette receptacle; and the second sensor apparatus is configured to detect activation of the first sensor apparatus and detect alignment of the cassette in a vertical plane with respect to the cassette receptacle.09-30-2010
20100030132APPARATUS AND METHOD FOR WOUND, CAVITY, AND BONE TREATMENT - The present invention provides a treatment apparatus. The apparatus contains a reservoir or generator for a treatment solution, a mechanism for delivering the treatment solution to a wound site, and a mechanism for applying the solution to a wound, tissue, bone or surgical cavity for treatment. The apparatus may apply the solution (e.g., a solution containing hypohalous acid) with, for example, an occlusive wound dressing, pulsative lavage device, hydrotherapy, hydrosurgical device, and/or ultrasound. A waste container may be operably connected to the apparatus for collecting waste from the wound by run-off, or by applying negative pressure (e.g. a vacuum). Because the apparatus of the invention can optionally be portable or mobile, the invention is suitable for use in hospitals and nursing homes, as well as for home wound care. The invention also provides a method for treating a wound (or other area needing treatment), and/or for reducing wound bioburden, by supplying a hypochlorous acid solution to the site, such as a wound colonized or infected with drug resistant bacteria, before, during, or after negative pressure wound therapy.02-04-2010
20110288473Vacuum Sense Control For Phaco Pulse Shaping - A method and apparatus for precisely controlling particle movement relative to a phacoemulsification needle tip is provided. The design monitors actual vacuum present and calculates a pulse shape amplitude waveform proportional to the amount of measured vacuum. An increase in vacuum indicates that the handpiece/needle is becoming occluded by a large particle. The present design determines whether additional power is required to bump or move a large particle away from the needle tip. The present design may employ a control loop that senses and continuously monitors vacuum. The design may dynamically vary the amount of ultrasonic energy delivered to the surgical area in response to the observed actual vacuum, and can actively vary the amount of power delivered to the surgical area based on the size of the particle and the resultant vacuum realized.11-24-2011
20110288471METHOD AND APPARATUS FOR PERFORMING INJECTIONS WHILE VIBRATING THE SKIN - An apparatus is provided for performing an injection, the apparatus including a front end, a vibrator mechanism selectively vibrating the front end during an injection and a syringe holder holding a syringe during an injection through the front end while the front end is vibrated.11-24-2011
20110288470GRAPHICAL USER INTERFACE FOR PHACOEMULSIFICATION SURGICAL SYSTEM - A graphical user interface for use in phacoemulsification surgical systems that allows a user to select different pulse modes by touching portions of the display screen. The user interface includes first and second display elements. One display element includes a representation of the on-time of the pulses, and the other display element includes a representation of the off-time. The representations show how the on-time and off-time change relative to a position of a controller, such as a foot pedal. The representation show a constant time, or that a time increases or decreases as the foot pedal is pressed. To select a pulse mode, a user can scroll through different pulse representations by touching the screen at the display elements. The selected pulse mode can be continuous, pulse, burst, or a combination or derivation thereof.11-24-2011
20110295191Infusion Pressure Monitoring System - An infusion pressure monitoring system for a phacoemulsification or vitrectomy machine to be operated by a health care provider includes an irrigation path configured to carry an irrigation solution to a surgical site and a fluid sensor configured to detect a fluid parameter in the irrigation path. An input device receives a variable fluid flow command from the health care provider commanding an irrigation fluid flow through the irrigation path at a flow rate corresponding to the command. A controller communicates with both the fluid sensor and the input device. The controller determines an expected fluid pressure value and a dynamically variable threshold pressure value based upon the variable fluid flow command.12-01-2011
20110295193OPHTHALMIC SURGERY KITS FOR PRIMING TUBES FOR OPHTHALMIC SURGICAL PROCEDURES - An ophthalmic surgery kit includes a priming vessel defining a reservoir for holding a fluid, an auxiliary aspiration channel, an irrigation channel, a handpiece channel, and an ophthalmic surgical handpiece retained by the handpiece channel. The ophthalmic surgical handpiece includes a tip disposed within the reservoir. An auxiliary aspiration tube 12-01-2011
20110295192HOLLOW NEEDLE FOR AN OPHTHALMIC SURGICAL INSTRUMENT - A hollow needle for an ophthalmic surgical instrument for the in-vivo fragmentation of organic lenses by way of ultrasound, comprising a connecting region (12-01-2011
20110288472BLADDER CANCER TREATMENT AND METHODS - Therapeutic compositions comprising an indoloquinone compound and various bladder cancer treatments and methods are disclosed. More specifically, bladder cancer treatments include the intravesical administration of apaziquone immediately following transurethral resection. Also disclosed are therapeutic compositions comprising an indoloquinone compound and a formulation vehicle. The formulation vehicle improves the solubility and stability of the indoloquinone compound. Additionally, the coating compositions can include coating agents that provide better adhesion of the coating composition to the bladder wall during intravesical delivery of the coating composition.11-24-2011
20100069828SYSTEMS AND METHODS FOR TRANSVERSE PHACOEMULSIFICATION - The invention is generally directed to phacoemulsification handpiece for providing transverse phacoemulsification. In accordance with one embodiment, a phacoemulsification handpiece is provided having a needle, wherein the handpiece is configured to vibrate the distal end of the needle in a transverse direction power is applied to the handpiece.03-18-2010
20120191034Infusion Sleeve With Leakage Control - An irrigation sleeve for a phacoemulsification needle has a collar to limit leakage of irrigating liquid in a direction forward of the sleeve when the sleeve is positioned on the needle. In one embodiment the sleeve and needle have mating grooves and ridges. In another embodiment an O-ring embedded in the sleeve forms a seal against the needle body.07-26-2012
20090281478VIBRATORY TROCAR - Devices and methods are provided for removing fluid from a trocar or from surgical instruments passed therethrough, and for preventing such fluid from accumulating. For example, an exemplary method for removing fluid from a trocar can include positioning a trocar to extend into a body cavity and vibrating the trocar to prevent fluid in the trocar from being deposited on surgical instruments passed therethrough. In one embodiment, the trocar can be selectively vibrated by activating a foot pedal or remote control, or according to an output of a sensor.11-12-2009
20110264032METHOD AND APPARATUS FOR THE ULTRASONIC CLEANING OF BIOFILM COATED SURFACES - To treat body surfaces, such as the sinuses, which are coated with biofilms, the surface is irrigated and suctioned with a fluid which may contain a biocide or other chemical agent for disrupting the biofilm while ultrasonic energy is applied to either the fluid barrier formed over the biofilm or a body surface proximal to the biofilm. Action of the fluid enhanced by the ultrasonic energy tends to remove sections of biofilm which are suctioned out of the site. An electrical field may also be applied to the biofilm to enhance the disruptive action. Apparatus for practicing this method to treat chronic rhinosinusitis comprises an elongated tube adapted to be inserted into sinus cavities through the nose or mouth. The tube includes a first lumen which feeds an irrigating fluid containing biocides and/or biofilm-disruptive chemicals to the treatment site and a second lumen which suctions fluid from the site. An ultrasound horn extends through the tube and its distal end introduces ultrasonic energy into the fluid layer overlying the biofilm. Alternatively, an ultrasound probe may be applied to an adjacent body surface, such as the face over a sinus cavity. In an alternative embodiment, the tube includes a pair of electrodes which establish an electric field across the biofilm, accelerating degradation.10-27-2011
20090312693SYSTEM AND METHOD FOR DELIVERING ENERGY TO TISSUE - Systems and methods for noninvasive skin treatment and deep tissue tightening are disclosed. An exemplary method and treatment system are configured for controlled thermal energy delivery to treat subdermal regions of the skin. First, specific control parameters such as power, skin temperature, and ultrasound frequency are chosen so as to provide localized delivery of ultrasound to a region of interest. Then, ultrasound energy is delivered at a frequency, depth, distribution, timing, and energy density to achieve the desired therapeutic effect.12-17-2009
20100114010VACUUM SENSE CONTROL FOR PHACO PULSE SHAPING - A method and apparatus for precisely controlling particle movement relative to a phacoemulsification needle tip is provided. The design monitors actual vacuum present and calculates a pulse shape amplitude waveform proportional to the amount of measured vacuum. An increase in vacuum indicates that the handpiece/needle is becoming occluded by a large particle. The present design determines whether additional power is required to bump or move a large particle away from the needle tip. The present design may employ a control loop that senses and continuously monitors vacuum. The design may dynamically vary the amount of ultrasonic energy delivered to the surgical area in response to the observed actual vacuum, and can actively vary the amount of power delivered to the surgical area based on the size of the particle and the resultant vacuum realized.05-06-2010
20100114009VACUUM SENSE CONTROL FOR PHACO PULSE SHAPING - A method and apparatus for precisely controlling particle movement relative to a phacoemulsification needle tip is provided. The design monitors actual vacuum present and calculates a pulse shape amplitude waveform proportional to the amount of measured vacuum. An increase in vacuum indicates that the handpiece/needle is becoming occluded by a large particle. The present design determines whether additional power is required to bump or move a large particle away from the needle tip. The present design may employ a control loop that senses and continuously monitors vacuum. The design may dynamically vary the amount of ultrasonic energy delivered to the surgical area in response to the observed actual vacuum, and can actively vary the amount of power delivered to the surgical area based on the size of the particle and the resultant vacuum realized.05-06-2010
20090312692SHEAR STRESS ULTRASONIC HORN FOR ULTRASONIC SURGICAL ASPIRATION - An ultrasonic horn for use with an ultrasonic surgical hand piece including a resonator comprises a contacting annulus having a plurality of angled lands. The lands are alternated around the annulus such that adjacent lands have opposite angles. As a result of the adjacent angled lands, a shear stress field is developed in contacted tissue due to the promotion of refracted longitudinal ultrasonic waves propagating in different directions at the interface to the coupled tissue. The shear stress field enhances the fragmentation and removal rate of fibrous, elastic, and tenacious tissue. The horn is hollow permitting suction to be applied to the tissue for controlling tissue contact with the lands.12-17-2009
20110270154APPARATUS AND METHOD FOR REDUCING PAIN DURING SKIN PUNCTURING PROCEDURES - A handheld instrument for minimizing pain during administration by injection of a liquid, such as, an anesthetic that has a main body, a vibration unit mounted in the main body when initiated to cause the main body to vibrate, and a detachable tip cantilever mounted on the main body to vibrate with it, the tip having a free end characterized by a bifurcation to form two spaced projections defining a space between them, whereby the spaced projections can be placed in proximity to, adjacent to and bracketing a preselected injection site on a human or animal and the tissue at said preselected injection site and vibrated while an injection is given.11-03-2011
20110125082MULTI-FUNCTIONAL SECOND INSTRUMENT FOR CATARACT REMOVAL - Apparatus for the removal of lens tissue includes a first instrument for inserting into a lens capsule and removing a cataract therein, the first instrument including a lumen for aspiration of cataract tissue and irrigation fluid from the lens capsule and manipulate the cataract until cataract is removed. The second instrument includes an irrigation port for introducing the irrigation fluid into the lens capsule.05-26-2011
20100268152Method and apparatus for ultrasound assisted local delivery of drugs and biomarkers - The current invention provides an ultrasound-assisted delivery device, that includes a focused ultrasound transducer having an ultrasound focal point, a real-time imaging device having an imaging focal point, and a therapeutic delivery device, where the transducer and the imaging device are integrated with the delivery device, and the ultrasound focal point coincides with the imaging focal point, where the delivery device and transducer are disposed to provide an unobstructed imaging path for the real-time imaging device. The invention further includes a scanning optical or laser beam having a focal point disposed to sweep across the target, where the delivery device is disposed to deliver an optical contrast material to the target, and the scanning focal point coincides with the ultrasound and imaging focal points, where the target or the optical contrast material react to the scanning beam to generate at least one interface signal.10-21-2010
20080281254Independent Surgical Center - A biological tissue cutting and fluid aspiration system provides a plurality of surgical instruments operable independent of an external control console. In some embodiments, each surgical instrument may include all sensors and controls directly applicable to the surgical instrument, and may be used independently. In some embodiments, instruments communicate status information to each other, and adjust operating parameters based on the communications.11-13-2008
20110137234METHODS FOR ESTABLISHING SUPPLEMENTAL BLOOD FLOW IN THE CIRCULATORY SYSTEM - A blood circulation assist system comprising an inflow cannula having a lumen and an insertion device configured to be received therein and to facilitate insertion of a portion of the inflow cannula into a heart chamber. The insertion device includes a shaft having distal and proximal end portions and a plurality of lumens. A first lumen is configured to receive a guidewire and a second lumen is configured to receive a pressurized fluid. A tip connected to the distal end portion of the shaft is configured for insertion into the heart chamber. The tip has a hollow interior communicating with the first shaft lumen. An inflatable member is coupled to the distal end portion of the shaft and includes a hollow interior in fluid communication with the second shaft lumen. The inflatable member is movable between deflated and inflated configurations for releasably securing the insertion device to the inflow cannula.06-09-2011
20090082715System and Method For Actuation of A Vitreous Cutter - Embodiments of systems and methods disclosed herein regard simplifying and improving the performance and reliability of pneumatic actuators operable to actuate surgical cutters or shears. Various embodiments include systems and methods for vitreous cutting apparatuses utilizing self-valving vitreous cutters that actuate at a frequency based on the properties of the vitreous cutter.03-26-2009
20110201996NASAL VENTILATION SYSTEM AND METHOD OF USING SAME - An apparatus for creating an accessory maxillary ostium for purposes of ventilation, irrigation, or procedural work within the maxillary antrum. An introducer having a ventilation tube and grommet is provided to create and then provide access through the accessory maxillary ostium. An irrigation catheter may be advanced through the ventilation tube in order to irrigate or express the contents of the sinus cavities. A secondary irrigation catheter or a balloon catheter may be advanced through an outer irrigation catheter, deeply into the sinus cavity, in order to irrigate or express the contents of the sinus cavities. Moreover, the balloon catheter may alternatively or additionally be employed to for dilation of the natural ostium. Still further, a device for delivering drugs, fluids or the like, may be coupled to the ventilation tube for delivery of same.08-18-2011
20080208109TREATMENT OF VASCULAR OCCLUSIONS USING ULTRASONIC ENERGY AND MICROBUBBLES - In one embodiment of the present invention, a method of treating a vascular occlusion located at a treatment site within a patient's vasculature comprises positioning an ultrasound catheter at the treatment site. The method further comprises delivering a microbubble therapeutic compound from the ultrasound catheter to the vascular occlusion during a first treatment phase. The method further comprises pausing the delivery of the microbubble therapeutic compound and delivering ultrasonic energy from the ultrasound catheter to the vascular occlusion during a second treatment phase while the delivery of microbubble therapeutic compound remains paused.08-28-2008
20100100032CHEST DRAINAGE AND APPARATUS FOR THE INSERTION THEREOF - An apparatus for the introduction of a drainage tube into a patient's chest cavity, comprising a housing having a distal end, a proximal end, and a longitudinal axis; a scalpel operable in a protruding position between a closed position in which the cutting portions are adjacent one another and adapted to make an incision in the dermis of the patient, and an open position in which the cutting portions are spaced from one another forming a scalpel passage along the longitudinal axis between the cutting portions. The apparatus further comprising a trocar comprising first and second trocar portions, each extending along the length of the trocar; the trocar being operable between an closed position wherein the first and second trocar portions are substantially adjacent one another, and a closed position in which the first and second trocar portions are spaced from one another and adapted for the introduction of the drainage tube therethrough.04-22-2010
20090275879METHOD FOR TREATING SUBCUTANEOUS TISSUES - An apparatus and method for treating subcutaneous tissues using acoustic waves in the range of low acoustic pressure ultrasound waves is disclosed. The method includes injections of enhancing agents, wherein disruption of subcutaneous tissues and subcutaneous cavitational bioeffects are produced by ultrasound waves having a power that will not produce tissue cavitation in the absence of the enhancing agents. The apparatus and method of use is useful for treatment of subcutaneous abnormalities including cellulite, lipomas, and tumors.11-05-2009
20090281479PNEUMATIC VITREOTOME - A vitreotomy device comprises a body extended by a cannula. The cannula has a closed distal end; it includes a window in its side wall close to said distal end. It houses a needle driven with reciprocating motion and capable of periodically closing said window. The device further comprises suction means connected to the needle, and a double-acting cylinder provided with a moving piston for controlling the movement of said needle. In said device, the needle is driven with reciprocating motion in translation in said cannula; said piston of the double-acting cylinder is secured directly to said needle; as a result, its movements enable the needle to be moved into a first position in which said needle closes said window, and a second position in which the needle leaves said window open. The device makes it possible to control very accurately the lengths of time for which the end of the cannula is open and closed.11-12-2009
20090287143Small Gauge Mechanical Tissue Cutter/Aspirator Probe For Glaucoma Surgery - A small gauge mechanical tissue cutter/aspirator probe useful for removing the trabecular meshwork of a human eye has a generally cylindrical outer cannula, an inner cannula that reciprocates in the outer cannula, a port located near or at the distal end of the outer cannula on a side or tip of the outer cannula, and a guide with a distal surface located on the distal end of the outer cannula. A distance between the distal surface of the guide and the port is approximately equal to the distance between the back wall of Schlemm's canal and the trabecular meshwork.11-19-2009
20120271222ULTRASOUND BASED COSMETIC THERAPY METHOD AND APPARATUS - A waveguide couples an acoustic source (such as an ultrasound transducer) to a cosmetic product (such as a liquid or gel-based skin care product) applied to the skin. In one representative embodiment, a distal surface of the waveguide is placed in contact with a relatively thin layer of skin care product that has been applied to the skin. Alternatively, the thin layer can be applied to the distal face of the waveguide, and then the waveguide placed on the skin. The cosmetic product may be formulated such that when ultrasound energy is directed into the cosmetic product via the waveguide, microspheres in the cosmetic product oscillate and increase the permeability of the skin to active beneficial agents included in the cosmetic product.10-25-2012
20120271221DELIVERY DEVICES AND METHODS WITH COLLIMATED GAS STREAM AND PARTICLE SOURCE - Delivery devices, methods and systems are provided for the delivery of particles into a biological tissue. The device includes a gas source comprising a gas or capable of selectively producing a gas; a first particle source comprising a first plurality of particles; a first collimator fluidly connected with the gas source and adapted to form a collimated stream of the first plurality of particles entrained in the gas. The device also includes a tissue-interfacing surface adapted to interface with a surface of the tissue and orient the first collimator with the tissue such that the collimated stream of the first plurality of particles will penetrate the tissue in a direction substantially perpendicular to the surface of the tissue.10-25-2012
20080275379Ultrasonic tip for sinus membrane elevation - An ultrasonic tip (11-06-2008
20100286594Device for Treating Hardened Lesions and Method of Use Thereof - A balloon catheter is provided that may be used to dilate hardened regions of a stenosis on a vessel wall. The balloon catheter is provided with cutting elements that extend along a surface of a balloon. At least one bioactive is present, either on the cutting element, within the interior of the balloon, within the material of the balloon or on an outside surface of the balloon. The bioactive is delivered to the vessel wall upon dilation of the balloon.11-11-2010
20120035531ON-DEMAND AND REVERSIBLE DRUG RELEASE BY EXTERNAL CUE - The invention provides a method to release drugs from a polymer matrix upon demand without degrading the matrix. By applying ultrasound to a self-healable polymer matrix in physiological environment, compounds of both low-molecular and high-molecular weights encapsulated in the matrix are delivered at controlled rates, while the integrity and stiffness of the matrix are unaffected.02-09-2012
20110270155DEVICE FOR RENDERING INJECTABLE DERMIS - Volume filling and/or augmentation are improved by harvesting live dermis from a donor and processing the dermis for re-injection into the donor. A variety of kits, tools, and methods are described for harvesting, processing, and using injectable dermis in volume filling procedures.11-03-2011
20090048558INJECTABLE DERMIS - Volume filling and/or augmentation are improved by harvesting live dermis from a donor and processing the dermis for re-injection into the donor. A variety of kits, tools, and methods are described for harvesting, processing, and using injectable dermis in volume filling procedures.02-19-2009
20080269667Handpiece for Ultrasonic Electro-Medical Apparatuses - The proposed handpiece (10-30-2008
20080281253Method of Operating an Ultrasound Handpiece - A method employing a handpiece having at least one set of piezoelectric elements polarized to produce longitudinal motion when excited at the relevant resonant frequency. The piezoelectric crystals are connected to an ultrasonic horn to which a cutting tip is attached. The horn and/or the cutting tip contains a plurality of diagonal slits or grooves. The slits or grooves produce optimized torsional movement in the cutting tip when the piezoelectric crystals are excited at a second resonant frequency. When in torsional mode, material may clog the cutting tip. The present method includes the step of providing a pulse of longitudinal movement of the tip when clogging is detected.11-13-2008
20080281255METHODS AND SYSTEMS FOR MODULATING MEDICANTS USING ACOUSTIC ENERGY - This invention provides methods and systems uniquely capable of enhancing medicant delivery and/or effectiveness through the use of energy to predictably disrupt membranes and mechanically and thermally modulate cells and tissues. In exemplary embodiments, the methods and systems disclosed herein are capable of modulating multiple layers of tissue. In an exemplary embodiment, the energy is acoustic energy (e.g., ultrasound). In other exemplary embodiments, the energy is photon based energy (e.g., IPL, LED, laser, white light, etc.), or other energy forms, such radio frequency electric currents, or various combinations of acoustic energy, electromagnetic energy and other energy forms or energy absorbers such as cooling. Medicants can be first introduced to the region of interest by diffusion, circulation, and/or injection. An exemplary system for enhancing medicant delivery and/or effectiveness comprises a control system, a probe, and a display or indicator system. Imaging and/or monitoring may alternatively be coupled and/or co-housed with an ultrasound system contemplated by the present invention.11-13-2008
20080287860SURGICAL NAVIGATION SYSTEM WITH A TRACKABLE ULTRASOUND CATHETER - A surgical navigation system including an ultrasound catheter is disclosed herein. The ultrasound catheter includes a flexible catheter housing defining a distal end, a transducer array disposed at least partially within the catheter housing, and a motor coupled with the transducer array. The motor is configured to rotate the transducer array in order to image a three-dimensional volume. The ultrasound catheter also includes a tracking element adapted to provide an estimate of a position and/or orientation of the distal end of the catheter housing. The tracking element is disposed within the catheter housing and immediately adjacent to the distal end.11-20-2008
20100036312APPARATUS AND METHODS FOR REMOVING OBSTRUCTIVE MATERIAL FROM BODY LUMENS - An apparatus is provided for removing material within a body lumen that includes a catheter including a proximal end, a distal end for introduction into a body lumen, and an aspiration lumen extending therebetween; a guide member extending from the distal end and terminating in a distal tip, the guide member comprising a track adjacent a track lumen extending from the distal tip into the aspiration lumen; and an obstruction clearing device deployable from the guide member and retractable along the track. In addition or alternatively, the apparatus includes a cutting head reciprocable within the aspiration lumen adjacent the distal end for macerating material being aspirated into the aspiration lumen.02-11-2010
20100298763SURGICAL MICRO-BURRING INSTRUMENT AND METHOD OF PERFORMING SINUS SURGERY - A surgical micro-burring instrument including an outer tubular member coaxially maintaining an inner tubular member. The outer tubular member defines a proximal section, a distal section, and a central lumen extending from the proximal section to the distal section. The distal section forms a pocket and an elevator tip. The pocket has a bottom wall and an opposed upper opening. The elevator tip extends distal the pocket. The inner tubular member forms a bur received within the pocket. Upon final assembly, at least a portion of the bur is exposed relative to the outer tubular member via the upper opening of the pocket. The elevator tip is configured to facilitate lifting of soft tissue, such as mucosa, while positioning the bur, via the pocket, in an appropriate location for cutting contacted harder tissue, such as turbinate bone or septal bone/cartilage.11-25-2010
20080221506SMALL VESSEL ULTRASOUND CATHTER - An ultrasound catheter adapted for accessing small vessels in the distal anatomy is disclosed. The ultrasound catheter comprises an elongate tubular body formed with a delivery lumen. The flexibility and dimensions of the tubular body allow access to the distal anatomy by advancement over the guidewire. An ultrasound radiating member is provided along the distal end portion of the tubular body for emitting ultrasound energy at a treatment site. A drug solution may also be delivered through the delivery lumen and out an exit port to the treatment site.09-11-2008
20110208114CUTTING NEEDLE TIP FOR SURGICAL INSTRUMENT08-25-2011
20110208113Directed Cell-Based Therapy Using Microbubble Tagged Cells - The disclosed technology describes compositions and methods useful for providing cell based therapy. For example, one embodiment of cell based therapy involves the regeneration of injured tissue and/or promoting wound healing. Certain embodiments provide improved therapeutic compositions using microbubbles by delivering biological progenitor cells to the injured tissues. The administration of the microbubbles is directed by acoustic radiation forces that interact with embodiments of microbubbles comprising an acoustically active gas. As such, a high efficiency of progenitor cell delivery to injured tissue is realized. One advantage of this technique over targeted delivery of pharmaceutical compounds, is that the delivered progenitors cells may be derived from the patient (i.e., personalized therapy), thereby avoiding side effects, allergic reactions, and overall problems associated with refractive drug responses.08-25-2011
20090182260Dual-passage surgical device - A medical device for performing a surgical procedure is described. The medical device comprises a housing having a sidewall extending along a longitudinal axis. A primary passage in the housing extends from an open proximal housing end to a hypodermic needle at a distal end. A secondary passage extends from the open proximal housing end to a distal opening in the housing sidewall adjacent to the hypodermic needle. The secondary passage provides for administering a medicine to the surgical site through the distal opening in the housing sidewall without removing the needle device from the body. That way, the primary passage enables a surgeon to administer a first drug or medicine to a surgical site during a surgical procedure. If needed, the surgeon can administer a second drug or medicine to the surgical site through the secondary passage.07-16-2009
20090143716METHODS AND SYSTEMS FOR REPAIRING AN INTERVERTEBRAL DISC USING A TRANSCORPORAL APPROACH - The invention includes a system and methods for performing surgery on a spinal disc. The system includes an implantable bone plate with an access port to accommodate a bone cutting device, a spinal repair device insertable through the access port of the bone plate configured to occupy a surgically-formed vertebral channel from an anterior surface of the host vertebral body to a site central to an end plate of the host vertebral body, a trajectory control sleeve engageable to the bone plate to direct the trajectory of a cutting device, and a cutting device engageable within the trajectory control sleeve. Methods are directed to forming a vertebral channel and restoring the vertebral body and disc with devices that both repair the bone and the disc.06-04-2009
20090187136ULTRASONIC SYRINGE METHOD - The present invention relates to an ultrasonic syringe and method of use for delivery and withdrawal of fluids from a human and/or animal patient. The ultrasonic syringe apparatus comprises a generator, a movable ultrasound transducer, a barrel, an ultrasound transducer tip, a radiation surface, an orifice located at the front end of the barrel, and a syringe head. The apparatus may further comprise a channel, a valve located on the distal end of the channel, and an orifice within the side wall which enables fluids to be delivered into the barrel. Ultrasonic waves emitting from the radiation surface induce vibrations within the fluids, sonicating the fluids, thereby eliminating the pain and discomfort associated with receiving injections, reducing and/or eliminating the force required to administer the injection, decreasing delivery time of the fluids into the body, and delivering ultrasonic energy to the tissue via the sonicated fluids.07-23-2009
20090177140Method of Stimulating the Body - A method for driving moisturizing substances and/or cosmetic active ingredients into the skin of the human body has skin brought into contact with the substances and/or active ingredients and a compression element applied thereto. Then, the tissue is subsequently set into oscillation. The compression element may be formed by compression bandages or compression wraps. The tissue may be set into oscillation in that the person locates himself on a vibrating support, or that the muscles of the person are stimulated by way of electro-stimulation.07-09-2009
20090187137ULTRASOUND PULSE SHAPING - In one embodiment of the present invention, an ultrasound catheter system comprising a catheter having at least one ultrasonic element; and a control system configured to generate power parameters to drive the ultrasonic element to generate ultrasonic energy is provided. The control system is configured to provide an ultrasonic pulse with a high pressure gradient with respect to time and/or distance. In another embodiment, a method of enhancing delivery of a therapeutic compound comprising delivering the therapeutic compound to a treatment site in a patient; and exposing the treatment site to an ultrasonic energy generated by an oscillating electrical signal pattern having a rise or fall rate greater than an sinusoidal pattern for the same amplitude and frequency is provided.07-23-2009
20090143717Device For Suction-Assisted Lipectomy And Method Of Using Same - A device is described which allows simultaneous application of suction or vacuum for evacuation of fat with application of energy to the fat inside an opening in a cannula. A pair of electrodes is situated within the cavity of the cannula just under the surface of cannula tip opening(s) or as part of the walls of such openings. The electrodes are spaced to allow coagulation of fat entering the cannula. Irrigation may be applied in a continuous or discontinuous or intermittent stream within the cannula to cool the tip and facilitate removal of suctioned tissue and prevent buildup of debris on electrodes. A method for using the cannula to remove adipose tissue or fat destroyed by the energy application through the use of suction with mechanical motion of the cannula, with energy application and optionally with the use of irrigation is also disclosed.06-04-2009
20080319376METHOD AND APPARATUS FOR TREATMENT OF INTRACRANIAL HEMORRHAGES - An ultrasound catheter with fluid delivery lumens, fluid evacuation lumens and a light source is used for the treatment of intracerebral hemorrhages. After the catheter is inserted into a blood clot in the brain, a lytic drug can be delivered to the blood clot via the fluid delivery lumens while applying ultrasonic energy to the treatment site. As the blood clot is dissolved, the liquefied blood clot can be removed by evacuation through the fluid evacuation lumens.12-25-2008
20090326440Piezotome for maxillary sinus operation - A piezotome operation unit for lifting a maxillary sinus at a position of placement of an implant upon lifting the maxillary sinus, which forms and enlarges the vertical hole with ease in a remaining bone of the maxillary sinus though vertical approaching, and upon forming a lateral window below a malar bone through lateral approaching, prevents a maxillary membrane from becoming damaged, thereby ensuring continuous, safe lifting so that the operating time is shortened and the efficiency of the operation is maximized.12-31-2009
20090326441Ultrasonic Enhanced Microneedles - The invention provides an injection device for injecting a substance into a subject. The device comprises an injector and an enhancer for enhancing the rate of penetration of the substance into the subject. The injector comprises a microneedle support and at least one microneedle extending from a first surface of said support. The or each microneedle has a fluid channel extending through the microneedle and through the support. The fluid channel of the or each microneedle has an inlet aperture in a second surface of the support and an outlet aperture in the microneedle.12-31-2009
20090209900DEVICE AND METHOD FOR OPENING VASCULAR OBSTRUCTIONS - The present invention is directed to a device and method for opening obstructed body internal passages and for sensing and characterizing tissues and substances being in contact with the device of the invention. In general, the device of the present invention comprises a catheter tube capable of inducing vibrations in a guidewire contained therein, wherein said vibrations of the guidewire are utilized for opening a passage through an occlusion. The in-vivo vibrations may be induced by means of a magnetic field actuating means (08-20-2009
20090024076Nozzle for ultrasound wound treatment - A nozzle for ultrasound wound treatment comprising a main body with proximal and distal ends, a reservoir and valve. The proximal end of the nozzle being removably attached to an ultrasound transducer. The distal end of the nozzle being marginally close and coaxial to the free distal end of the ultrasound transducer. The body of the nozzle connected with liquid reservoir, which holds the wound treatment solution and delivers same to the free end of ultrasound tip directly or through a tube. The nozzle is provided with valve for controlling flow rate of wound treatment solution. The nozzle can mix different liquids or a liquid with a gas and deliver same to the wound surface.01-22-2009
20080306432CUTTING APPARATUS WITH ULTRASONIC TRANSDUCER - A cutting apparatus includes a blade mount supporting a first ultrasonic transducer for imparting ultrasonic vibrations to a cutting blade. The blade mount includes an annular flange having a grip surface on an outer circumferential side surface thereof for gripping the cutting blade, a first ultrasonic transducer housing portion for housing the first ultrasonic transducer, and a hollow cylindrical mount boss having a fitting hole fitting over the spindle. The annular flange has a plurality of through holes defined therein between the first ultrasonic transducer housing portion and the mount boss. A blade grip flange has a fitting hole fitted over the mount boss, a grip surface on an outer circumferential side surface thereof for gripping the cutting blade, a second ultrasonic transducer housing portion for housing a second ultrasonic transducer, and a plurality of through holes defined therein between the second ultrasonic transducer housing portion and the fitting hole.12-11-2008
20090082717Dermal micro-organs, methods and apparatuses for producing and using the same - Embodiments of the present invention provide Dermal Micro-organs (DMOs), methods and apparatuses for producing the same. Some embodiments of the invention provide a DMO including a plurality of dermal components, which substantially retain the micro-architecture and three dimensional structure of the dermal tissue from which they are derived, having dimensions selected so as to allow passive diffusion of adequate nutrients and gases to cells of the DMO and diffusion of cellular waste out of the cells so as to minimize cellular toxicity and concomitant death due to insufficient nutrition and accumulation of waste in the DMO. Some embodiments of the invention provide methods and apparatuses for harvesting the DMO. An apparatus for harvesting the DMO may include, according to some exemplary embodiments, a support configuration to support a skin-related tissue structure from which the DMO is to be harvested, and a cutting tool able to separate the DMO from the skin-related tissue structure. Other embodiments are described and claimed.03-26-2009
20090192442APPARATUS AND METHOD FOR TREATING THE SKIN - A device for treating the skin comprises a handpiece assembly having a distal end and a proximal end, a cartridge comprising an interior cavity and a tip on the distal end of the handpiece assembly. The handpiece assembly includes a fluid delivery conduit and a waste conduit. In addition, the cartridge is coupled to the handpiece assembly with the interior cavity of the cartridge being in fluid communication with the fluid delivery conduit. Further, the tip is configured to contact the skin. The tip comprises a peripheral lip, a first opening in fluid communication with the fluid delivery conduit, a second opening in fluid communication with the waste conduit and an abrasive element. The first opening, the second opening and the abrasive element of the tip are generally positioned within the peripheral lip.07-30-2009
20110144567Phacoemulsification Hand Piece With Integrated Aspiration Pump and Cartridge - An ophthalmic surgical hand piece comprises a driver coupled to a horn. The horn is coupled to a needle. An aspiration pump is integral with the hand piece and is located close to the needle. The aspiration pump comprises a motor coupled to a shaft. A removable cartridge comprises a length of flexible tubing held by a tubing holder. The length of flexible tubing is located between the shaft and the tubing holder. The removable cartridge comprises a section of an aspiration line.06-16-2011
20090192441Liposuction system - A surgical tool such as a liposuction cannula is equipped with a sensor at the tool tip. The sensor continuously analyzes the type of tissue in contact with the tip based on the electrical properties of the tissue. When encountering a tissue type that should not be disturbed, the action of the surgical tool is stopped automatically. When used for liposuction, the cannula is mechanically decoupled from the handle when the wrong type of tissue is detected thus minimizing the inertia of the part that needs to be stopped. Besides electrical sensing, other sensors, such as mechanical or ultrasonic, can be used at the tip of the surgical tool or cannula to differentiate between tissue types07-30-2009
20110230818CUTTING BALLOON AND PROCESS - A method of preparing a cutting balloon comprises the steps of providing a balloon body having an exterior surface, an unexpanded state and an expanded state; and engaging at least one blade to the exterior surface when the balloon body is in the unexpanded state.09-22-2011
20090182261Fluid Ejecting Apparatus, Surgical Operation Instrument - A fluid ejecting apparatus includes: a fluid ejecting unit that ejects fluid from a fluid ejecting opening in pulses by reducing the capacity of a fluid chamber by a diaphragm; an inlet channel that supplies the fluid to the fluid chamber; and a check valve formed on the diaphragm and disposed between the inlet channel and the fluid chamber, in which the check valve closes the inlet channel when the capacity of the fluid chamber is reduced, and the check valve is bent when the capacity of the fluid chamber is expanded from the reduced state to open the inlet channel.07-16-2009
20120078165ELEMENT FOR IMPLANTATION WITH MEDICAL DEVICE - A therapeutic agent eluting element includes an elongate body member and one or more therapeutic agents elutable from the body member. The elongate body member is configured to be implanted subcutaneously along side of a therapy delivery element. The elongate body member may be formed from a polymeric material, and the agent eluting element may consist essentially of the body member and the one or more therapeutic agents. The therapeutic agent eluting element may be a part of a system or kit that includes a therapy delivery element and a tunneling tool, such as a dilator, sheath, catheter passer, or the like.03-29-2012
20120078164MEDICAL TOOL FOR REDUCED PENETRATION FORCE - A medical device is provided having reduced penetration force. The device includes a body having a central hollow channel and a piezoelectric transducer received within and secured to the body. The piezoelectric transducer has a hollow portion concentric with the central hollow channel. A tubular member is associated with and in communication with the piezoelectric transducer. The tubular member has at least one open end formed concentric with the central hollow channel and the hollow portion of the piezoelectric transducer, wherein the transducer is adapted for vibrating at a frequency to produce an oscillating displacement of the tubular member.03-29-2012
20090204061METHOD AND APPARATUS FOR TREATING CELLULITE - A device and a method for treating cellulite is disclosed. An oscillation therapy device includes a body, a motor, a drive shaft powered by the motor, and a contact surface coupled to the drive shaft, which may be substantially enclosed in a covering adapted to frictionally engage human skin. The motor and drive shaft drive the contact surface to impart an oscillating motion to the contact surface and to skin in contact with the surface.08-13-2009
20090221955ABLATIVE ULTRASONIC-CRYOGENIC METHODS - An ablative apparatus and associated methods that can be used to treat atrial fibrillation and other cardiac arryhythmias by ablating cardiac tissue is disclosed. When the distal end of the apparatus reaches the tissue to be ablated, an ablation probe driven by a transducer is vibrated. Scratching the tissue with abrasive members, the vibrating ablation probe is capable of mechanically ablating tissues. This mechanical ablation may be utilized to penetrate epicardial fat, thereby exposing the underlying myocardium. The ablative apparatus may then be used subject the exposed myocardium to mechanical ablation, cryoablation, ultrasonic ablation, and/or any combination thereof.09-03-2009
20120197181Device for inoculating a veterinary product into a poultry bird's wing - The invention pertains to a device for inoculating at least one veterinary product into at least one poultry bird, said inoculating having to be performed on the wing-web membrane situated in the front part of the wing and extending between the radius and the humerus of the wing, characterized in that the device comprises: 08-02-2012
20090247936STREAMLINED ULTRASONIC DEVICE AND METHOD OF USE - A phacoemulsification device that features an applicator tip as in a cutting tip for insertion into an eye and into contact with a cataract. The device includes a shaft having a phacoemulsification movement generator connector end at a proximal location and an applicator tip supporting end at a distal end, and the shaft further includes a shaft section that extends in a region positioned between the proximal and distal ends of the shaft, and the shaft section having a convoluted exposed surface which includes longitudinally extending projections and longitudinally extending valleys arranged in sequence about the circumference of the shaft section. The projections are formed in an exemplary embodiment as to be free of any edges as in, for example, an embodiment that includes projections and valleys that have smooth sloped curving walls in cross section and which smooth sloped curving walls include a plurality of mirror image S-shaped regions extending from a maximum radial extension region of a first projection, down to a maximum depth valley region of a first valley and up to a maximum radial projection of a second projection, with the valley region being positioned between respective first and second projections.10-01-2009
20090192439DEVICES, SYSTEMS AND METHODS FOR TREATING BENIGN PROSTATIC HYPERPLASIA AND OTHER CONDITIONS - Devices, systems and methods for compressing, cutting, incising, reconfiguring, remodeling, attaching, repositioning, supporting, dislocating or altering the composition of tissues or anatomical structures to alter their positional or force relationship to other tissues or anatomical structures. In some applications, the invention may be used to used to improve patency or fluid flow through a body lumen or cavity (e.g., to limit constriction of the urethra by an enlarged prostate gland).07-30-2009
20100160851Gilled phacoemulsification irrigation sleeve - A phacoemulsification irrigation sleeve includes an elongated, resilient, tubular body section configured to surround a portion of a shaft of a phacoemulsification needle, the tubular body section having a distal end and a proximal end, and an inner surface and an outer surface. An enlarged section formed on the proximal end of the tubular body portion surrounds a hub of the phacoemulsification needle and connects the irrigation sleeve to a phacoemulsification handpiece. The irrigation sleeve further comprises at least one slitted irrigation port formed adjacent to the distal end of the body section and configured to splay in response to a drop in pressure between the inner surface and the outer surface.06-24-2010
20100262070ULTRASONIC MEDICINE PASTE - An ultrasonic medicine paste for transdermally permeating a medicine to a body and the manufacture method thereof. The medicine paste includes an adhesive layer (10-14-2010
20100191176SUBRETINAL ACCESS DEVICE - The invention provides surgical devices that provide access to the sub-retinal space using delicate traction to hold the sensory retina to create and maintain a patent sub-retinal space of sufficient size to introduce and perform treatments on the eye. Such treatments may include the introduction of illumination or imaging agents or tools, surgical tools, the infusion of pharmaceutical or biological agents, and the placement of grafts, transplants or implants and the closure of the site through the delivery of a sealant.07-29-2010
20110060271CREATING, DIRECTING AND STEERING REGIONS OF INTENSITY OF WAVE PROPAGATION IN INHOMOGENEOUS MEDIA - Known time reversal methods consist of three steps which may be listed as (i) the recording of signals and (ii) the time reversing of the recorded signals, and (iii) the transmission of the time-reversed signals. The first and third steps of the above process are retained, but the second step is modified. The empirical signal is transformed to fit mathematical forms taught by the mathematics of singularity and catastrophe theory that ensure a structural stability to the waveforms that will be received, when the time reversed signals are transmitted again. This structural stability ensures robustness of the waveform and the predominant direction of the flux of energy of the waveform, and improves controllability of the location of the high magnitude regions of the energy flux despite limited knowledge of the exact properties of the medium. Applications to drug delivery in the brain, and geophysical applications are envisaged.03-10-2011
20110060270Microporation of Tissue for Delivery Of Bioactive Agents - A method of enhancing the permeability of a biological membrane, including the skin or mucosa of an animal or the outer layer of a plant to a permeant is described utilizing microporation of selected depth and optionally one or more of sonic, electromagnetic, mechanical and thermal energy and a chemical enhancer. Microporation is accomplished to form a micropore of selected depth in the biological membrane and the porated site is contacted with the permeant. Additional permeation enhancement measures may be applied to the site to enhance both the flux rate of the permeant into the organism through the micropores as well as into targeted tissues within the organism.03-10-2011
20110130710TREATMENT OF ABNORMAL OR EXCESSIVE SCARS - Methods, compounds, compositions, kits and articles of manufacture comprising anti-connexin polynucleotides for prevention and/or treatment of abnormal scars, including keloid scars, hypertrophic scars, atrophic scars, and widespread scars.06-02-2011
20110112466Extended Point Phacoemulsification Tip - In various embodiments, a phacoemulsification tip may be configured with a proximal end configured to be secured to a phacoemulsification hand piece and a distal end shaped as a five-sided polygon with five corners. In some embodiments, at least two of the five corners of the five-sided polygon may form a right angle and one of the five corners may form a dominant point spaced further from an axis of rotation of the five-sided polygon than any of the other four corners. For example, the distal end may be shaped in a home base configuration. The displacement of the dominant point from the axis of rotation may improve cutting and/or improve the removal of lens material. In some embodiments, the dominant point may form a sharper edge than at least one of the other four corners (e.g., the other four corners may be rounded).05-12-2011
20130218068THERAPEUTICS RESERVOIR - A method and system of forming at least one therapeutic reservoir in a target tissue by trapping therapeutics in at least a portion of said target tissue by selectively applying energy to said target tissue. Optionally, trapping comprises preventing said therapeutics in said target tissue from being carried away by a circulation. The system can include a catheter with both an ultrasonic element and a drug delivery port, optionally connected to control circuitry.08-22-2013
20110130711HAIR GROWTH TREATMENT - The present disclosure provides methods and systems for increasing hair growth in subjects in need thereof due to male- or female-pattern hair loss, pathological hair loss, or hair loss after injury. By any use of any appropriate mechanical, electromagnetic, or chemical means, the present disclosure pertains to the segmentation of hair follicles into two or more disunited subunits in order to form new follicles from the respective subunits. In contrast with known techniques for bisecting hair follicles and as described more fully herein, the present methods and systems permit the bisection of single follicles or populations of follicles with a high degree of efficiency, and thereby represent an effective treatment option for those in need of increased hair growth.06-02-2011
20090318851LEAKAGE-RESISTANT TISSUE TREATMENT APPARATUS AND METHODS OF USING SUCH TISSUE TREATMENT APPARATUS - Apparatus and methods for treating skin conditions that deliver high frequency energy to a patient's tissue. The apparatus has a treatment tip configured to be removably connected with a handpiece, a conduit inside the handpiece, and a flow control valve inside the handpiece. The treatment tip has an electrode configured to deliver the high frequency energy to a region of the tissue. A lumen of the conduit is configured to transfer a heat transfer fluid from the handpiece to a flow passageway in the treatment tip. When the treatment tip is removed from the handpiece, the flow control valve is configured to occlude the lumen of the conduit for reducing leakage of the heat transfer fluid from the handpiece.12-24-2009
20090318853ULTRASOUND BASED COSMETIC THERAPY METHOD AND APPARATUS - A waveguide couples an acoustic source (such as an ultrasound transducer) to a custom cosmetic product (e.g., a liquid or gel-based skin care product) applied to the skin. In one exemplary embodiment, a distal surface of the waveguide is placed in contact with a relatively thin layer of skin care product that has been applied to the skin. Alternatively, the thin layer can be applied to the distal face of the waveguide, and then the waveguide placed on the skin. The custom cosmetic product has been formulated such that when ultrasound energy is directed into the custom cosmetic product via the waveguide, bubbles included or formed in the custom cosmetic product oscillate, and increase the permeability of the skin to active beneficial agents included in the custom cosmetic product.12-24-2009
20090318852ULTRASOUND BASED COSMETIC THERAPY METHOD AND APPARATUS - A waveguide couples an acoustic source (such as an ultrasound transducer) to a custom cosmetic product (e.g., a liquid or gel-based skin care product) applied to the skin. In one exemplary embodiment, a distal surface of the waveguide is placed in contact with a relatively thin layer of skin care product that has been applied to the skin. Alternatively, the thin layer can be applied to the distal face of the waveguide, and then the waveguide placed on the skin. The custom cosmetic product has been formulated such that when ultrasound energy is directed into the custom cosmetic product via the waveguide, bubbles included or formed in the custom cosmetic product oscillate, and increase the permeability of the skin to active beneficial agents included in the custom cosmetic product.12-24-2009
20090112150CAVITATION ENHANCED TREATMENT THROUGH LOCAL DELIVERY - A method is disclosed to administer to a patient in need thereof a therapeutically effective amount of one or more therapeutic agents. The method provides a patient comprising a blood vessel, supplies a therapeutic agent comprising a plurality of gas-filled microspheres, and supplies a catheter comprising a proximal end, a distal end, and an infusion length disposed adjacent the distal end, where that infusion length is formed to include an infusion pattern comprising a plurality of apertures extending therethrough. The method catheterizes the blood vessel using the catheter, prepares an aqueous mixture comprising the first therapeutic agent, disposes that aqueous mixture in a container, interconnects the container to the proximal end of said catheter, and administers the aqueous mixture into the blood vessel through the plurality of apertures extending through the catheter.04-30-2009
20080249460DUAL-SIDED PADDLE FOR USE WITH VIBRATIONAL ENERGY UNDER 1000 HERTZ FOR DERMATOLOGICAL TREATMENT - A treatment paddle is used with a system for dermatological treatment of an individual's skin area. The treatment paddle consists of a first dermatological treatment surface having a sufficiently abrasive side for vibratory removal of an outer skin area of an individual. A second dermatological treatment surface located on an opposite side of the first dermatological treatment surface has a side specifically adapted for the vibratory infusion of a cream, lotion or other dermatological aid into the underlying skin area of said individual. A stem defines first and second ends. The first end of the stem is integrated with the first and second dermatological surfaces and the second end of the stem is adapted for connecting to a vibrational unit to receive vibrational energy therefrom.10-09-2008
20130131578Ophthalmic System and a Computer Program Product - The invention relates to an ophthalmic system for controlling an infusion liquid pressure at a distal end of an ophthalmic irrigation device penetrating an eye and being connected to an irrigation line for feeding the device with an infusion liquid. The system comprises a processor that is arranged for estimating a compensation pressure for compensating an internal pressure loss in the eye due to surgical acts in the eye. The estimation result is used for dynamically adjusting, in response to the estimated compensation pressure, the pressure of the irrigation liquid in the irrigation line. The estimation step is based on a configuration and/or actual operation of an ophthalmic surgical device performing the surgical acts in the eye.05-23-2013
20110112467Systems and methods for improving image-guided tissue ablation - The cryosurgical kit and method of use relates to the combined use of biodegradable, imageable, drug(s) carriers, vectors or microcapsules deposited into a target tissue region inside a body and the controlled cooling of the target tissue region. A minimally invasive method of treatment that applies a cooling device to a selected tissue region, uses a vibrating resonant frequency delivery device to inject drug(s) carriers (microcapsules) containing therapeutic and contrast agents into tissue region(s) submitted to cooling temperatures, successive real-time imaging of the microcapsule deposition and later detection of the progressive degradation of microcapsules with ultrasound imaging which provides estimation of sustained release rates and for planning re-dosing regimens. The thermosensitive microcapsules preferably contain ethiodol, a contrast agent for Ultrasound and/or X-Ray imaging, and cytotoxic drug (s).05-12-2011
20090069742Electronic Module for Mechanical Medication Delivery Devices - The present invention relates to a method for monitoring the operation of a medication delivery device. In particular, the present invention relates to a method comprising the steps of arranging an electronic module in the vicinity of the medication delivery device, detecting, using the electronic module, measurable signals generated in response to an action occurring within the associated medication delivery device, and storing, using storage means of the electronic module, information associated with or representing the measured signals. The present invention further relates to an electronic module capable of performing the above-mentioned method.03-12-2009
20090069741Methods And Devices For Fractional Ablation Of Tissue For Substance Delivery - Methods and devices for ablating portions of a tissue volume with electromagnetic radiation (EMR) to produce lattices of EMR-treated ablation islets in the tissue are disclosed, including lattices of micro-holes, micro-grooves, and other structures. Also, methods and devices for using the ablated islets are disclosed, including to deliver chromophores, filler, drugs and other substances to the tissue volume.03-12-2009
20110172590Infusion Sleeve With Distendable Port - An infusion sleeve for use with a phacoemulsification needle has a hollow body with an open end by which the sleeve is attachable to a handpiece and an open tip through which a phacoemulsification needle is passed. Irrigating liquid is directed from the handpiece through the sleeve. At least one discharge ports is formed in the sleeve to provide increased flow of irrigating liquid into the eye. The port or ports may differ in size, shape and positioning on the sleeve. At least one such port has a slit extending therefrom cutting through the sleeve and adapted to distend or open up under certain flow conditions, effectively increasing the cross-sectional area of the port available for flow. When flow conditions return to normal the slit returns to its “closed” position. Another such port is formed as a flap which opens and closes responsive to the flow of the irrigating liquid.07-14-2011
20110172589Surgical instrument having an integrated local anesthetic delivery system - A surgical instrument includes a handle portion having a distal end, a proximal end, and a substantially hollow body defining a valve chamber therein; a curved incising tube partially housed within the handle portion adjacent the handle portion proximal end, extending a predetermined distance from the handle portion, and in fluid communication with the valve chamber; a local anesthetic inlet tube partially housed within the handle portion adjacent the handle portion distal end, extending a predetermined distance from the handle portion, and in fluid communication with the valve chamber; a local anesthetic delivery actuator disposed on the handle portion, whereby the local anesthetic delivery actuator is selectively operative between opened and closed valve chamber positions.07-14-2011
20110172588Phacoemulsification Needle - A phacoemulsification needle having a central, hollow passageway terminates in a straight, enlarged needle tip formed off-axis from the passageway, allowing the needle tip to move eccentrically when the needle is subjected to torsional vibratory motion.07-14-2011
20100331763ULTRASOUND CATHETER WITH EMBEDDED CONDUCTORS - An ultrasound catheter comprises an elongate tubular body is disclosed. The elongate tubular body has a proximal region and a distal region opposite the proximal region. The tubular body defines a central lumen having a central lumen surface that is electrically conductive. The ultrasound catheter further comprises an elongate, hollow inner core extending through the central lumen and has an inner core outer surface that is electrically conductive. The ultrasound catheter further comprises an ultrasound radiating member positioned within the distal region of the tubular body and between the tubular body and the inner core, such that the tubular body conductive surface and the inner core conductive surface are both in electrical contact with the ultrasound radiating member. The ultrasound catheter further comprises an insulating sleeve positioned between the tubular body and the inner core in a region proximal to the ultrasound radiating member.12-30-2010
20100331764Controlling A Phacoemulsification Surgical System By Transitioning Between Pulse and Burst Modes - Methods of manipulating pulses of ultrasonic energy for use with an ophthalmic surgical device.12-30-2010
20110040238INTERVENTIONAL CATHETER ASSEMBLIES INCORPORATING GUIDE WIRE BRAKE AND MANAGEMENT SYSTEMS - Interventional catheter assemblies that operate over a guide wire and incorporate guide wire management systems are disclosed. Specifically, a guide wire buffer zone is provided between a proximal end of the interventional catheter and the guide wire clamp that accommodates variable lengths of exposed guide wire in an unrestrained condition when the guide wire is clamped, allowing the distal end of the operating catheter to be advanced and retracted over the distal end of the guide wire without repositioning and reclamping the proximal end of the guide wire. The configuration of the guide wire buffer zone may be adjusted prior to or during an intervention based on the anticipated range of axial motion of the catheter and operating head relative to the guide wire.02-17-2011
20110046542APPARATUS AND METHODS FOR CLOT DISSOLUTION - Clot disruption and dissolution are achieved using a catheter having the ability to infuse a thrombolytic agent, aspirate clot and fluid, and allow passage of a guidewire. Optionally, the catheter may also include a mechanical agitator for further disrupt clot in the presence of the thrombolytic agent. A flow resistor in the catheter provides for infusion and/or aspiration to be concentrated primarily at a clot treatment area in a blood vessel while also providing optional infusion and/or aspiration distal to the treatment area. In some embodiments, infusion, aspiration and guidewire passage occur through a common lumen. The thrombolytic agent, such as tPA, streptokinase, or urokinase, is directly released into the clot at the point where the agitator is engaging the clot. In this way, the thrombolytic activity of the agent is enhanced and the dissolution of the clot is improved.02-24-2011
20110046541Phacoemulsification Needle Tip with Interior Step - A phacoemulsification needle is provided for use with a high-frequency phacoemulsification handpiece with the needle tip having a land formed on the interior of the tip proximate the tip opening, creating a “stepped” configuration.02-24-2011
20110245758TOPICAL ANESTHETIC AND ANTISEPTIC DISPENSING DEVICE - Embodiments of the present invention provide a topical anesthetic and antiseptic dispensing device article of manufacture. In an embodiment of the invention, the article of manufacture includes a penetrating instrument including an elongated body with first and second distal end such that at least one of the distal ends includes a penetrating edge. By way of example, the penetrating instrument can be a syringe, an IV catheter needle assembly, a pressurized tube holder configured with a needle for blood draw, or a scalpel, to name a few possibilities. The article of manufacture also includes a container coupled to the elongated body of the penetrating instrument. The container provides at least one chamber. Finally, the article of manufacture includes a nozzle connected to the container and configured to dispense pressurized content of the container responsive to activating a trigger communicating with the nozzle.10-06-2011
20110245757METHOD FOR TREATING CHRONIC WOUNDS WITH AN EXTRACELLULAR POLYMERIC SUBSTANCE SOLVATING SYSTEM - Chronic wounds may be treated by debriding necrotic and other devitalized tissue from the wound, and applying to the wound an extracellular polymeric substance solvating system comprising a metal ion sequestering agent, surfactant and buffering agent. The solvating system disrupts biofilms which may be present in the wound and aids or enables the resumption of normal healing.10-06-2011
20110087157Use of Pressure Waves for Stimulation, Proliferation, Differentiation and Post-Implantation Viability of Stem Cells - Stem cells are proliferated with the application of acoustic pressure waves, including cambium cells of periosteum treated in-vivo with acoustic pressure waves. Following harvesting and viability assessment of in-vivo or in-vitro proliferated stem cells, acoustic pressure waves are applied to enhance in-vivo or in-vitro differentiation either before or after implantation of the stems cells to an organism. Acoustic pressure waves also stimulate an implantation site to enhance viability and to grow desired tissue.04-14-2011
20110087156APPLICATION OF A SYSTEM PARAMETER AS A METHOD AND MECHANISM FOR CONTROLLING EYE CHAMBER STABILITY - A controller for a phacoemulsification system having a handpiece; an irrigation fluid source configured to supply an irrigation fluid to the eye; an aspiration source configured to aspirate the irrigation fluid from the eye through the handpiece; and a controller comprising a duration timer configured to provide a duration of an occlusion, the controller configured to: sense a value of an occlusion indicating parameter corresponding to an occlusion of the handpiece; measure a time since the occlusion of the handpiece; and control the aspiration source to the handpiece based at least in part on the measured time since the occlusion. The occlusion indicating_parameter may be a vacuum level, an irrigation flow rate, and/or an aspiration flow rate.04-14-2011
20090082716Linear to Torsional Converter for Phaco Handpieces - A linear-to-torsional converter changes the linear motion imparted by a phaco handpiece to torsional or rotational motion. The converter attaches to the needle mount of a conventional linear handpiece. A lock can be used to defeat the torsional motion and restore linear motion without requiring the converter to be removed from the handpiece. Alternatively the converter can be built into a handpiece.03-26-2009
20110087158APPARATUS HAVING A FIBROUS SKIN-CONTACTABLE ELEMENT CONTAINING AN AGENT - The invention features an apparatus for delivering mechanical energy to an expanse of skin, wherein the apparatus includes: (a) a skin-contactable element having a skin-contactable surface, wherein the skin-contactable element includes an agent selected from the group consisting of a benefit agent, an apparatus-enhancing agent, and combinations thereof; (b) a motor; and (c) a transfer member for transferring mechanical energy from the motor to the skin-contactable element in order to provide periodic motion to the skin-contactable surface; wherein the agent is configured to release from the skin contactable element to the expanse of skin upon contacting the skin-contactable surface with the expanse of skin.04-14-2011
20110105999Coextensive Tubing System for Phacoemulsification Handpieces - An irrigation and aspiration tubing system for use with surgical handpieces and irrigation fluid supplies has a flexible tube with first and second lumens formed integrally along its length, with a first lumen used for transporting irrigation fluid to the handpiece and a second lumen used for aspiration of fluid and emulsified particles from a surgical site. The cross-sectional area of the first lumen is selected to provide a cross-sectional area available for fluid flow in excess of the cross-sectional area of a standard surgical irrigation tubes. The system also includes at least one adaptor to allow the tubing to be attached to known surgical handpieces. Preferably, a second adaptor is also provided allowing attachment to sources of irrigating fluid and aspiration vacuum. One said lumen is formed integral with either the interior or exterior surface of the flexible tube.05-05-2011
20100069827Pre-Surgical Prophylactic Administration of Antibiotics and Therapeutic Agents - Antibiotics are administered in a surgical site subcutaneously via a small or stab incision in the surgical field. Transcutaneous ultrasonic vibrations are applied across the surgical field, which is then opened in the usual manner, to thereby provide a surgical field which contains a vastly higher and more effective level of antibiotic. At the same time the underlying tissue is hydrated.03-18-2010
20090216180METHODS AND DEVICES FOR CUTTING TISSUE - A catheter is provided, which includes a cutting element having one or more raised elements. The cutting element has a cup-shaped surface at the distal end that may be smooth and continuous except for the raised elements.08-27-2009
20090216179Deflector Shield For Use With Multiple Wound Care Devices - This invention discloses deflector shields to protect an operator from splashing from the use of hand-held ultrasound wound care devices. The deflector shield is for use with an ultrasound generator, ultrasound tip with a radiation surface and a fluid to serve as a coupling medium between the radiation surface and wound surface. The deflector shield is used to protect the operator from splashing fluid and removed tissue. The deflector shield consists of a hub portion and conical portion. The deflector shield is preferably transparent, disposable and easily installed. The deflector shield is preferably useable on several hand-held ultrasound wound care devices.08-27-2009
20090216178Method And Apparatus For Preventing Localized Stasis Of Cerebrospinal Fluid - A system and method for treating, inhibiting or ameliorating Alzheimer's disease in a patient, comprising one or more transducers operatively connected to a power source for radiating vibrational or acoustical energy to the maxilla of the patient, wherein the energy is sufficient to radiate through the paranasal sinuses of the patient to the base of the patient's skull to assist in cerebrospinal fluid clearance and inhibit localized stasis of cerebrospinal fluid in the brain.08-27-2009
20100130914Method Of Controlling A Surgical System Based On Irrigation Flow - A surgical system that is able to sense the onset of an occlusion or other surgical event as well as the instant an occlusion breaks. To help avoid overheating of the tip, the system determines a temperature of an eye using irrigation flow rate and reduces the power to the handpiece automatically if an overheating situation is predicted. Alternatively or in addition, the system monitors the power drawn by the handpiece, which is indicative of the cutting load on the tip, and automatically adjusts the power or stroke of the tip to compensate for increased loads on the tip.05-27-2010
20110082415DEVICES, SYSTEMS AND METHODS FOR TREATING THE SKIN USING TIME-RELEASE SUBSTANCES - According to some embodiments, a microdermabrasion device for treating skin comprises a handpiece assembly having a distal end and a proximal end. The handpiece assembly includes at least one delivery conduit and at least one waste conduit. The microdermabrasion device additionally comprises a tip configured to be positioned along the distal end of the handpiece assembly, wherein the tip is adapted to contact skin surface. In several embodiments, the tip comprises a lip, a first opening in fluid communication with the fluid delivery conduit and a second opening in fluid communication with the waste conduit. In one embodiment, the device includes one or more abrasive elements positioned along a distal end of the tip, wherein the abrasive elements are configured to selectively remove skin as the tip is moved relative to a skin surface. In some embodiments, the delivery conduit is configured to selectively deliver at least one time-release material to the skin surface being treated.04-07-2011
20110251547TRANSFECTION WITH MAGNETIC NANOPARTICLES AND ULTRASOUND - The invention includes a magnetic nanoparticle molecular delivery vehicle to be used for transfection and delivery of therapeutic molecules across cell membranes and to specific sites in the body, using magnetic forces and ultrasound.10-13-2011
20110251546MEDICAMENT MICRODEVICE DELIVERY SYSTEM, CARTRIDGE AND METHOD OF USE - A method and device for intradermal delivery of a reconstituted medicament. The device includes a chamber, which is in fluid communication with a microdevice, e.g. microabrader or one or more microneedles. A cartridge containing the medicament may be located within said chamber. At least one burstable membrane retains a medicament within the housing. The method involves the steps of positioning the device at a delivery site on the skin of a patient and intradermally administering the medicament by dispensing a diluent from a diluent source an through inlet port to rupture the membranes, reconstitute the medicament and deliver the reconstituted medicament through the microdevice to the dermal region of the skin.10-13-2011
20110098633ULTRASONIC TIP FOR SINUS MEMBRANE ELEVATION - Method for lifting a sinus membrane located between a sinus and a maxilla that involves the drilling of a hole of a given diameter in the maxilla reaching the sinus membrane, and includes introducing in the hole an ultrasonic tip having a distal part including a ring-shaped part of increasing cross-section and a distal end formed by a flat area extending generally perpendicular to the longitudinal axis of the distal part. The flat area of the distal part has a distal side facing away from the proximal part and is bordered by a rounding, the ring shaped part being larger than the body of the tip but closely corresponding to the diameter of the hole. The tip includes an internal irrigation channel emerging on the distal side of the flat area. While the tip is within the hole, the tip is advanced towards the membrane while ultrasound vibrations are fed to the tip and irrigation fluid is supplied to the internal irrigation channel. This creates a cavitation effect in the irrigation fluid between the tip and the membrane and a lifting force that gently detaches and elevates the sinus membrane without requiring a direct contact between the membrane and the distal part of the tip.04-28-2011
20110077583System and method for pulsed ultrasonic power delivery employing cavitational effects - A method and apparatus for delivering energy during a surgical procedure such as phacoemulsification is provided. The method and apparatus include delivering energy during a surgical procedure, including applying energy at a level and for a time period sufficient to induce transient cavitation, and reducing applied energy after applying energy during a second nonzero lower energy period.03-31-2011
20120065578Phacoemulsification Hand Piece with Two Independent Transducers - An ophthalmic surgical hand piece has a horn and two transducers. The horn has a central axis. A flange having a generally flat surface is coupled to the horn. The flange extends radially from the horn and generally perpendicular to the central axis. A first ear having a generally flat surface is coupled to the horn. The first ear extends from the horn such that the generally flat surface of the first ear is generally perpendicular to the generally flat surface of the flange. A first transducer is held against the flange, and a second transducer held against the ear.03-15-2012
20110071460System and method for modulated surgical procedure irrigation and aspiration - A method and apparatus for performing modulated fluid delivery and aspiration during a surgical procedure such as phacoemulsification is provided. The method and apparatus include delivering fluid and/or aspirating fluid in a modulated or pulsed manner during a surgical procedure, including applying fluid and/or aspirating fluid in connection with ultrasonic energy at a level and for a time period sufficient to induce transient cavitation. Fluid may be applied and/or aspirated at a timing sequence and duty cycle similar to or different from application of ultrasonic energy delivery.03-24-2011
20120203164DEVICE AND METHOD FOR DRUG DELIVERY TO A TARGETED SKIN LAYER - The present invention relates to a device and method for the controlled delivery of a drug to a targeted layer of the skin in a human or animal subject. In particular, the present invention relates to such a device, system and method for selective drug delivery to the cutaneous or subcutaneous layer of skin to enhances the effectiveness of the drug delivery.08-09-2012
20120302941PHACOEMULSIFICATION SYSTEMS AND ASSOCIATED USER-INTERFACES AND METHODS - Phacoemulsification systems and associated user interfaces and methods for use in ophthalmic surgery are disclosed. In some embodiments, a touch screen display of an ophthalmic surgical console provides a graphical user interface that allows a user to both visualize and control various operating parameters of the surgical console and associated subsystems. The controllable operating parameters include, without limitation, aspiration flow rates, IV pole height, vacuum limit pressures, minimum ultrasound power, maximum ultrasound power, on-time, off-time, and/or other values associated with the operating parameters of the ophthalmic surgical console.11-29-2012
20110257588Skin treatment and drug delivery device - A new minimally invasive surgical approach is proposed that contemplates a method and apparatus for tightening lax skin without visible scarring via a device in various surgical procedures such as plastic surgery procedures. In some embodiments, the device is a single use disposable instrument. This approach circumvents surgically related scarring and the clinical variability of electromagnetic heating of the skin and performs small multiple pixilated resections of skin as a minimally invasive alternative to large Plastic surgical resections of skin. This approach can also be employed in areas of the body that are currently off limits to plastic surgery due to the visibility of the surgical scar. In addition, the approach can perform a skin grafting operation by harvesting the transected incisions of skin from a tissue site of a donor onto a skin defect site of a recipient with reduced scarring of the patient's donor site.10-20-2011
20110178457DEVICE FOR REDUCING PRESSURE VARIATIONS IN AN ASPIRATION BRANCH, AND SURGICAL SYSTEM - The invention relates to a device for reducing pressure variations in a fluid flowing in an aspiration branch of a surgical system, which pressure variations are generated by a pump that delivers in a non-continuous manner in the active operating state, with a diffuser arrangement which is arranged, in the aspiration branch, upstream of the pump in the direction of flow of the fluid. The invention also relates to a surgical system, in particular an ophthalmic microsurgical system for lens surgery.07-21-2011
20100069826PLAQUE LIBERATING DEVICE - A device and method for liberating plaque from a lumen after a medical procedure has been formed. The device includes a catheter having a first expandable member and a second expandable member.03-18-2010
20100004586Ultrasound Handpiece - A handpiece having at least one set of piezoelectric elements polarized to produce longitudinal motion when excited at the relevant resonant frequency. The piezoelectric crystals are connected to an ultrasonic horn to which a cutting tip is attached. The horn and/or the cutting tip contains a plurality of diagonal slits or grooves. The slits or grooves produce optimized torsional movement in the cutting tip when the piezoelectric crystals are excited at a second resonant frequency.01-07-2010
20100004585Ultrasonic Handpiece - A handpiece having a single set of piezoelectric elements polarized to produce longitudinal motion when excited at the relevant resonant frequency. The piezoelectric crystals are connected to an ultrasonic horn to which a cutting tip is attached. The horn and/or the cutting tip contains a plurality of diagonal slits or grooves. The slits or grooves produce optimized torsional movement in the cutting tip when the piezoelectric crystals are excited at a second resonant frequency. Preferably, the two drive frequencies are not coincident, but provided in non-overlapping pulses.01-07-2010
20100198136Chlorine Dioxide Treatment for Biological Tissue - Methods, compositions, devices, and systems for administration to a biological tissue of a composition comprising a chlorine dioxide source are provided.08-05-2010
20120203163CATHETER FOR USE IN REVASCULARIZATION PROCEDURES AND METHOD OF USING SAME - A method of removing vascular blockage includes providing a catheter system comprising an outer catheter with a serrated cutting element at its distal end, a bypass catheter, and a guidewire. In the catheter system, the bypass catheter is slidably disposed within the outer catheter. The method includes positioning a distal portion of the catheter system at a proximal end of an occlusion located within a vessel and moving the bypass catheter through the occlusion so that a medicated treatment solution may be delivered through the bypass catheter to an area of the brain or other tissue served by the vessel blocked by the occlusion. Both during and after the delivery of medicated treatment solution to the blocked part of the vessel with the bypass catheter, the physician may engage the occlusion with the cutting element by moving the outer catheter in a clockwise/counterclockwise or forward/backward direction within the outer catheter, cutting and then removing at least a portion of the occlusion from the vessel.08-09-2012
20080275378METHOD AND APPARATUS FOR THE FORMATION OF MULTIPLE MICROCONDUITS - Disclosed is an apparatus that creates a number of microconduits, i.e., small holes in the stratum corneum, the outermost layer of human skin tissue, to provide a pathway therethrough, which can be used, for example, for transdermal drug delivery.11-06-2008
20110166504PHACO THERMAL CONTROL APPARATUS AND METHOD - Control apparatus for an ultrasonic phacoemulsification handpiece utilizes flow rates and temperature measurements as well as power provided to a handpiece for calculating a matrix of power level duty cycle combination that would not generate sufficient heat to create a burn in eye tissue and either prevent operation of handpiece in the matrix or alert a surgeon of such use.07-07-2011
20110054386VIBRATING ANESTHESIA DEVICE - The hand-held vibration anesthesia tool of the present invention includes a housing in which a battery, vibratory motor, switch and light source are enclosed. A switch turns the motor and light on and off. A tip extends from the housing for touching a patient's skin. When the motor is actuated, vibrations are transmitted through the tip to the skin to create an anesthetized zone. The light defines a target for the needle or other treatment adjacent the tip.03-03-2011
20110054385OPHTHALMOSURGICAL SYSTEM - The disclosure relates to an ophthalmosurgical system that includes a first irrigation fluid source. The system also includes a first irrigation fluid line connected to the first irrigation fluid source at a first end and open at the other end. The system further includes an aspiration fluid line, by which fluid can be removed from the ocular lens. In addition, the system includes a suction pump, to which the aspiration fluid line is connected, and a second irrigation fluid source, to which a second irrigation fluid line is connected. The second irrigation fluid line is connected to the first irrigation fluid line at a coupling site. The system also includes a first valve, which is disposed between the first end of the first irrigation fluid line and the coupling site, and a second valve, which is disposed between the second irrigation fluid source and the coupling site.03-03-2011
20110054384Sonic Device for Use in Capsule of Eye - This invention relates to an improved procedure for polishing the interior of the lens capsule after the lens is removed. The procedure includes removing the phacoemulsification instrument from the eye after the lens and cortex material have been removed and then placing a novel sonic tip over or within the needle portion of the instrument. The tip portion of the instrument is then reinserted into the lens capsule with a lower ultrasonic energy level. The sonic tip is then placed in close proximity or in direct contact with the interior surface of the lens capsule to remove any remaining small particles of the cortex or other cells.03-03-2011
20110021976METHOD AND DEVICE FOR TISSUE REMOVAL AND FOR DELIVERY OF A THERAPEUTIC AGENT OR BULKING AGENT - According to an aspect of the present invention, a medical device is provided, which comprises the following: (a) a hollow elongate body (e.g., a elongate cylinder, such as a needle) having distal and proximal ends; and (b) a rotatable member comprising a tissue morselizer and an elongate shaft (e.g., an auger-like tissue-drilling bit). In the devices of the present invention, the elongate shaft is disposed within the hollow elongate body and cooperates with the hollow elongate body to (i) advance material (e.g., morselated tissue) toward the proximal end of the hollow elongate body when the shaft is rotated in a first direction, and (ii) advance material (e.g., a therapeutic agent and/or a bulking agent) toward the distal end of the hollow elongate body when the shaft is rotated in a second direction that is opposite the first direction. According to another aspect of the invention a method of treatment is provided that comprises: (a) inserting the a medical device like that above into the tissue of a patient; (b) morselizing and removing tissue from within the patient while rotating the shaft in a first direction, thereby creating a void within the patient; and (c) introducing a therapeutic agent and/or a bulking agent into the void.01-27-2011
20100292632Transdermal Micro-Patch - A transdermal micro-patch for use with living tissue is provided. The micro-patch includes a first membrane, a reservoir, a micro-pump, flextensional transducers, a microelectronics circuit, and an optional sensor. The first membrane is permeable to allow the passage of fluid in either a unidirectional or bidirectional fashion. The reservoir is a container-like element capable of storing a fluid removed from or communicated into the tissue. The micro-pump facilitates transport of the fluid between the reservoir and first membrane. The flextensional transducers generate ultrasonic waves which are separately communicated into the tissue to transport fluid between the first membrane and tissue. Ultrasonic waves could interact to enhance the performance of the micro-patch. The microelectronics circuit controls both flextensional transducers and the micro-pump. The sensor could be embedded within the micro-patch to monitor temperature, pressure, or flow rate so as to avoid damage or irritation to the tissue.11-18-2010
20110137233VACUUM SURGE SUPPRESSOR FOR SURGICAL ASPIRATION SYSTEMS - An apparatus and method to suppress vacuum surges in a surgical aspiration system is disclosed and claimed. A vacuum surge suppressor includes a first fluid path for coupling to a surgical instrument, and a filter attached to the first fluid path. A flow restrictor is coupled to the filter with the filter disposed upstream of the flow restrictor. The vacuum surge suppressor also includes a second fluid path for coupling to a vacuum pump. The second fluid path is connected to the flow restrictor and disposed downstream of the flow restrictor. The second fluid path defines a path internal pressure. A third fluid path is coupled to the filter and is connected to the second fluid path, bypassing the flow restrictor. A valve in the third fluid path obstructs flow in the third fluid path in response to the path internal pressure.06-09-2011
20110137232Thermal Management Algorithm For Phacoemulsification System - A control system for managing power supplied to a phacoemulsification hand piece includes a power source that provides power to the hand piece and a controller that controls the power source. The controller calculates a thermal value based on irrigation fluid flow and a power level and decreases the power level in proportion to the calculated thermal value when the calculated thermal value exceeds a threshold thermal value. Irrigation fluid flow can be calculated from irrigation fluid pressure.06-09-2011
20100305496FLOW LIMITER FOR A FLUID FLOWING IN AN ASPIRATION BRANCH OF A SURGICAL SYSTEM, AND SURGICAL SYSTEM - The invention relates to a flow limiter (12-02-2010
20100324471Systems and Methods for Delivering Drugs to Selected Locations Within the Body - A transvascular system for delivering a drug to a tissue region from a blood vessel includes a catheter having a distal portion with puncturing, orientation, drug delivery, and imaging elements. The puncturing element is deployable for penetrating the vessel wall to access the tissue region. The orientation element has a predetermined relationship with the puncturing element, the imaging element detecting the location of the orientation element with respect to the tissue region to orient the puncturing element. The catheter is percutaneously introduced into the vessel, the puncturing element is oriented towards the tissue region, the puncturing element is deployed to access the tissue region, and the drug is delivered to the tissue region. An ablation device may also be deployed to create a cavity or fluid reservoir in the tissue region for receiving the drug therein, or an indwelling catheter may be advanced into and left in the tissue region.12-23-2010
20100324472DELIVERY AND ADMINISTRATION OF COMPOSITIONS USING INTERVENTIONAL CATHETERS - Systems and methods for delivery of therapeutic and/or diagnostic compositions to an interventional site having diseased or newly treated tissue are provided. Integrated interventional catheter systems incorporating surfaces coated with a therapeutic composition, or tissue penetration members for scoring or disrupting tissue prior to or during administration of a therapeutic composition are provided. Infusion of therapeutic composition(s) may also be provided.12-23-2010
20120029423Intraocular Pressure Control - An improved method of controlling intraocular pressure with a microsurgical system using measured flow rate.02-02-2012
20110137231Phacoemulsification Hand Piece With Integrated Aspiration Pump - An ophthalmic surgical hand piece comprises a driver coupled to a horn. The horn is coupled to a needle. An aspiration pump is integral with the hand piece and is located close to the needle. A rigid length of aspiration line is located between the aspiration pump and the needle. An optional pressure sensor is located between the aspiration pump and the needle as well.06-09-2011
20090171266COMBINATION THERAPY - There is provided a method for producing lysis of adipose tissue that includes applying focused ultrasonic energy to the adipose tissue and applying at least one additional therapeutic procedure to said adipose tissue or surrounding tissue. There is further provided a system for combination therapy for producing lysis of adipose tissue that includes a transducer adapted to apply focused ultrasonic energy to said adipose tissue and at least one additional unit adapted to provide a therapeutic procedure to said adipose tissue or surrounding tissue(s).07-02-2009
20100121258LATERAL INTRAVASCULAR EXCISION/INCISION DEVICES - Various cutting devices and systems are described that excise and/or incise tissue from a target site. For example, the wall of an artery and/or adventitial to the artery wall from inside the artery. According to embodiments of the invention, a lateral incision catheter device configured to be introduced intra-luminally to a pre-selected site in the body is provided, generally including a rotating first catheter, including a proximal end, a distal end and lumen positioned therebetween; a first shell to a first rotating catheter and having a cutting surface; a second shell attached to a second catheter, whereby rotation of the first rotating catheter causes the first shell to rotate with respect to the second shell so as to permit the cutting surface to cut tissue at the pre-selected site. According to embodiments of the invention, a lateral sliding incising/excising device configured to be introduced intra-luminally to a pre-selected site generally including a catheter, a lateral sliding cup including a cutting surface and at least one inflatable balloon attached to the outside of the cup and configured to push the cup laterally toward the target site.05-13-2010
20100121257CAPACITIVE FLUID LEVEL SENSING - A capacitive fluid level sensing arrangement for use in a medical device is provided. The arrangement includes at least one pair of conductive plates configured to increase and decrease the amount of electric charge stored in relation to the level of fluid within a fluid maintaining device, such as a reservoir. The conductive plates are electrically connected to a medical device and are configured to measure the charge stored between the plates and thus sense the fluid level. The electric circuit may communicate the measurement to an instrument host arrangement for operating a pump configured to remove fluid from the reservoir and move the fluid to a collector when the level exceeds a preset upper level amount. The instrument host arrangement may stop operating the pump when the fluid level is reduced to a preset lower level amount.05-13-2010
20100191178TISSUE REMOVAL DEVICES, SYSTEMS AND METHODS - A tissue removal device includes a cannula that can aspirate tissue, and a thermal element located at a tip of the cannula that can apply localized heat to the tissue to be aspirated. The tissue removal device may also include a device for applying a vacuum in the cannula, which may be configured for applying vacuum pulses according to a controlled pulse rate and vacuum level. The tissue removal device may also include a device for applying the heat at the tip according to a controllable pulse rate and power level.07-29-2010
20100280435AUTOMATICALLY SWITCHING DIFFERENT ASPIRATION LEVELS AND/OR PUMPS TO AN OCULAR PROBE - Methods and apparatuses for automatically switching different aspiration levels to an ocular probe are disclosed herein. The probe may be a phacoemulsification probe. A first aspiration level, supplied by a first pump, may be applied to the probe simultaneously with ultrasonic energy. A second aspiration level, supplied by a second pump, may be automatically switched from the first aspiration level. Control feed back of the pumps may be varied according to set thresholds.11-04-2010
20110218483METHOD FOR USING MICROELECTROMECHANICAL SYSTEMS TO GENERATE MOVEMENT IN A PHACOEMULSIFICATION HANDPIECE - The present invention relates to a phacoemulsification handpiece, comprising a needle and a microelectromechanical system (MEMS) device, wherein the needle is coupled with the MEMS device. The phacoemulsification handpiece may further comprise a horn, wherein the horn is coupled with the needle and the MEMS device. The MEMS device is capable of generating movement of the needle in at least one direction, wherein at least one direction is selected from the group consisting of transversal, torsional, and longitudinal. The present invention also relates to a method of generating movement, comprising providing a phacoemulsification handpiece, wherein the handpiece comprises a needle and one or more MEMS devices; applying a voltage or current to the one or more MEMS devices, wherein the MEMS devices are coupled with the needle; and moving the needle in at least one direction. The present invention also relates to a vitrectomy cutter comprising one or more MEMS devices.09-08-2011
20100016784POSITIONABLE MEDICAL SYSTEM FOR POSITIONING MEDICAL COMPONENTS ON OR WITHIN A BODY - Devices, systems and methods relating to delivery systems suitable for positioning various medical components within a patient's body and, more specifically, to delivery systems designed to cooperate with certain therapeutic and diagnostic devices.01-21-2010
20100016786DEVICES, METHODS, AND KITS FOR FORMING TRACTS IN TISSUE - Described here are methods and devices for forming tracts in tissue. Some of the devices comprise an elongate member, a suction member coupled to a distal portion of the elongate member, and a tissue-piercing member slidably housed within the elongate member for forming a tract in tissue. Other devices comprise more than one suction member. Methods for forming tracts in tissue are also described here. In some methods, a device is advanced adjacent tissue, where the device comprises one or more suction members and a tissue-piercing member. Suction is applied so that the tissue is drawn against the one or more suction members, and a tissue-piercing member is advanced in a first direction through the drawn tissue to form a tract in or through the tissue. Kits incorporating one or more of the devices described here, in conjunction with one or more tools or the like, are also described here.01-21-2010
20100016785Suction catheter and suction-catheter system - Provided is a suction catheter including: a catheter main body made of a flexible lengthy body having a lumen inside; a leading-end case portion positioned at a leading-end portion of the catheter main body and including an opening for retrieving an object; and object cutting means partially exposed through the opening and movable in the axial direction within the leading-end case portion. The object cutting means includes a cutting portion exposed through the opening portion, and a power receiving portion driving the cutting portion when receiving power from outside. A leading-end side of the suction catheter is inserted into a blood vessel while a base-end portion of the suction catheter is connected to a suction apparatus. An object sticking to the internal wall of the blood vessel is cut off by operating the object cutting means in the opening of the leading-end case portion while the lumen is vacuumed. The cut-off object is immediately sucked in and retrieved.01-21-2010
20090292238PAEONIFLORIN PREPARATIONS AND USES THEREOF FOR FAT REDUCTION - Disclosed are methods and preparations useful for reducing fat at a targeted area(s) on a human. The preparations comprise as an active ingredient an adipolysis enhancing (i.e., fat-melting) amount of an active ingredient, paeoniflorin (PF). The preparations may be provided as an injectable preparation or as a topically applied preparation, such as in the form of a crème or lotion. In topical preparations, the active ingredient paeoniflorin may be contained within nanospheres, such as albumin nanospheres. The PF-containing preparations may also include a permeant, such as azone. The method may be accompanied by the application of ultrasound to the area being treated prior to, during or after, or prior to, during, and after application of the paeoniflorin preparation to an area of the body in which fat reduction is desired. By way of example, the methods and preparations are effective for reducing targeted fat deposits at various anatomical sites of the body, such as the midsection (“love handles”), jowls, hips, arms, thighs and buttocks area.11-26-2009
20100292631Control flow device - The present invention relates to a flow control device for phacoemulsification procedures. The flow control device is valve which limits the vacuum surge that can occur when an occlusion in the phacoemulsification aspiration line is dislodged. The flow control device comprises; a body; a chamber formed therein; at least one inlet in communication with the chamber; and at least one outlet in communication with the chamber; wherein the chamber has at least a first portion and at least a second portion that are substantially divided by a member where the member has at least one restricted flow passage, and wherein the member is adapted to adjust a flow rate through the body by adjusting a flow resistance through the body responsive to the flow rate through the restricted flow passage within the device.11-18-2010
20100121259DEVICE AND SYSTEM FOR SKIN TREATMENT - A device, system and method for removing pigment from the skin through the application of fluid and vibrations to the skin.05-13-2010
20080312581Peptosomes for Use in Acoustically Mediated Intracellular Drug Delivery in vivo - Targeted therapeutic delivery systems comprising specially designed nanocarriers for intracellular therapeutic delivery, mediated by acoustic energy, for use either in vivo or in vitro, are described. Nanocarriers comprised of substantially peptosomes, and mixtures thereof, are used to treat a variety of diseases in humans and other species, such as cancer, opthalmological, pulmonary, urinary or other pathologies. Methods for preparing the targeted therapeutic delivery systems are also embodied, which comprise processing a solution comprised of biopolymers or other species and components, with or without targeting moieties, adding said biopolymers and other compounds to a solution containing one or more therapeutic agents, stabilizing or not stabilizing said nanocarriers, adding one or more contrast agents, and resulting in a targeted therapeutic delivery system. Preferred therapeutics for use with the present invention include nucleic acids, proteins, peptides, and other therapeutic macromolecules.12-18-2008
20100160852VARIABLE FREQUENCY PHACOEMULSIFICATION HANDPIECE - A phacoemulsification system includes a phacoemulsification handpiece having a horn coupled to a transducer configured to convert alternating current into mechanical oscillation of the horn. The phacoemulsification handpiece further includes a phacoemulsification needle attached to the horn. The phacoemulsification needle vibrates by oscillation of the horn, to provide for mechanical cutting of tissue and inducing cavitation proximate a tip of the phacoemulsification needle. The phacoemulsification system further includes a control system with associated drive circuitry in connection with the transducer of the phacoemulsification handpiece. The control system is configured to adjust an operating frequency of the transducer to increase or decrease a mechanical cutting performance and a cavitational-induced performance of the phacoemulsification needle.06-24-2010
20090247935Bioadhesive Applicator for ENT Surgery - The present disclosure relates to an electrosurgical suction coagulator and includes a housing having an elongated electrode and a fluid applicator. The elongated electrode includes distal and proximal ends and is adapted to connect to an energy source, for example, an electrosurgical generator. The proximal end of the elongated electrode is configured to operably couple to a distal end of the housing. Further, the distal end of the elongated electrode is configured to apply energy to tissue. The elongated electrode also includes a lumen defined therethrough, that is operably coupled to a vacuum source. The fluid applicator assembly is operably coupled to the elongated electrode and includes a container defining a reservoir. The reservoir is configured to contain a bioadhesive therein. The selectively dispensable from the container to deliver the bioadhesive to a surgical site.10-01-2009
20080275380SONIC ENDOVENOUS CATHETER - A device and method to improve the ultrasound visibility of a catheter placed inside the body is described. The catheter is sonically vibrated by an external driver device that transmits the acoustic vibration down the catheter and inside the body. An ultrasound transducer is used to pick up the ultrasound vibrations directly or detects the sonic vibrations using a Doppler mode ultrasound machine.11-06-2008
20130012868Vacuum Level Control of Power For Phacoemulsification Hand Piece - The present invention comprises a method of operating an ophthalmic surgical hand piece, providing a series of power pulses to the hand piece, each of the series of power pulses having a first portion that produces torsional movement of a cutting tip and a second portion that produces longitudinal movement of the cutting tip; measuring vacuum pressure; altering the duration of the first portion as vacuum pressure increases; and altering the duration of the second portion as vacuum pressure increases.01-10-2013
20110004150Transdermal Delivery Using Encapsulated Agent Activated by Ultrasound and or Heat - A method for delivery of substance through at least one dermal layer, by providing a substance in microcapsules at a predetermined size, within a medium (01-06-2011
20100191177DEVICE FOR ASPIRATING FLUIDS - Surgical devices are provided for aspiration of the subretinal fluid (SRF) of the eye in a retinal detachment that allows re-apposition of the sensory retina to the underlying RPE. The device is connected to a vacuum source, introduced into the posterior chamber through a sclerostomy port and placed against the detached retinal tissue. The device pulls on and captures the surface of the sensory retina, causing a micro needle to pierce through the tissue. As the sensory retina is captured and held in place by the vacuum, a protected pocket is created and the tissue is prevented from folding onto itself and occluding the micro needle tip.07-29-2010
20120041358One-Hand Device for Ophthalmic Surgery - A one-hand device for an ocular irrigation and aspiration has a tube (02-16-2012
20080243047ULTRASOUND WOUND CARE DEVICE - The present invention relates to a method of treating wounds by applying ultrasonic energy to a wound to inactivate, destroy, and/or remove infectious agents, and/or deliver a coupling medium to debride, cleanse, and/or sterilize the wound. The device of the present invention comprises an ultrasound generator, an ultrasound transducer, a transducer tip at the distal end of the ultrasound transducer, and a radiation surface tilted with respect to the longitudinal axis of the transducer tip. Ultrasonic waves emanating from the tilted radiation surface of the present invention may travel through the air directly to the wound, and/or may be applied to the wound through a coupling medium.10-02-2008
20120041359SYSTEMS AND METHODS FOR MIXING THERAPEUTIC AGENTS BEFORE AND/OR DURING ADMINISTRATION - The invention provides systems and methods for mixing of therapeutic agents before and/or during the localized application of the therapeutic agents. Most preferably, the present invention provides systems and methods for mixing of therapeutic agents before and/or during administration of the agents within a biological lumen. Various embodiments of the present invention comprise systems and methods for inducing a mixing state in the therapeutic agents, thereby inducing and/or maintaining homogeneity of the agents before and/or during localized delivery.02-16-2012
20120041360SYSTEMS AND METHODS FOR POWER AND FLOW RATE CONTROL - The invention is generally directed to systems and methods for fluid control, and more particularly to systems and methods for power and flow rate control for aspiration. In accordance with one embodiment, an aspiration system includes an aspiration line having distal and proximal ends and an aspiration port defined in the distal end; a fluid transport device operatively coupled to the proximal end of the aspiration line; and a flow restrictor operatively coupled to the aspiration line in between the fluid transport device and the aspiration port. To measure occlusion within the line, first and second pressure sensors are utilized, the first sensor being operatively coupled to the aspiration line between the port and the restrictor and the second sensor being operatively coupled to the aspiration line between the restrictor and the fluid transport device. The pressure differential between the two sensors can provide an indication of the onset, presence, and/or elimination of an occlusion.02-16-2012
20100069825SYSTEM AND METHOD FOR CONTROLLING A TRANSVERSE PHACOEMULSIFICATION SYSTEM USING SENSED DATA - A method and system for use in an ocular surgical procedure is provided. The design includes a handpiece having an ultrasonically vibrating tip operational within a plurality of operating modes including a first operating mode and a sensing device, such as a vacuum pressure sensor. A controller is connected to the handpiece and sensing device and is configured to receive data from the sensing device and adjust at least one operational parameter (time/duty cycle of operation, power during operation) associated with the first operating mode and adjust at least one parameter associated with another operating mode based on the data received from the sensing device. Operational modes may include multiple longitudinal or non-longitudinal modes (torsional, transversal, etc.) or combinations of longitudinal and/or non-longitudinal modes.03-18-2010
20120046601Methods for delivering novel cell and cell-based compositions - The invention is directed to methods for delivering cells or cytokine-containing solutions into body tissue using ultrasound (sonoporation). Such methods utilize novel compositions including Amnion-derived Multipotent Progenitor cells (herein referred to as AMP cells) and Amnion-derived Cellular Cytokine Solution (herein referred to as ACCS), each alone or in combination with each other and/or other agents and/or other treatment modalities.02-23-2012
20120046600HIGH-SPEED ROTATIONAL ATHERECTOMY SYSTEM, DEVICE AND METHOD FOR LOCALIZED APPLICATION OF THERAPEUTIC AGENTS TO A BIOLOGICAL CONDUIT - The invention provides a system, device and method for localized application of therapeutic agents within a biological conduit. A preferred biological conduit comprises a blood vessel. A preferred device comprises a high-speed rotational atherectomy device having, in various embodiments, a flexible, elongate non-rotatable therapeutic agent delivery sheath having a lumen therethrough and a flexible, elongated, rotatable, drive shaft with at least one flexible eccentric enlarged abrading head disposed within lumen of the delivery sheath. The operator may actuate a controlled amount or dose of one or more therapeutic agents to release from the distal end of the delivery sheath lumen during high-speed rotation of the drive shaft. The therapeutic agent(s) is thus released into a turbulent fluidic environment resulting from high-speed rotation and orbital motion of the eccentric abrading head, which aids to drivingly urge the therapeutic agent(s) radially through the boundary layer of fluid flow in the conduit and into the target region of the conduit wall.02-23-2012
20120046599THERAPEUTIC AGENT DELIVERY SYSTEM, DEVICE AND METHOD FOR LOCALIZED APPLICATION OF THERAPEUTIC SUBSTANCES TO A BIOLOGICAL CONDUIT - The invention provides a system, device and method for localized application of therapeutic substances within a biological conduit after the lumen wall has been scored by an eccentric scoring head. One embodiment comprises radial scoring with the eccentric scoring head, with a therapeutic agent coated balloon inflated distal to the scoring and dragged proximally through the scoring. Another embodiment comprises inflation of two anchor balloons on either side of scoring with subsequent inflation of a therapeutic agent coated balloon therebetween which causes the distance between anchor balloons to increase, thus stretching the scoring crevices while applying the agent therein with subsequent closure of crevices on deflation of anchor and application balloons. Another embodiment comprises an inflated anchor balloon with a threaded scoring device wherein the scoring members are coated with agent and rotation of the threaded device enables travel in the proximal direction away from anchor balloon.02-23-2012
20120004592COMPOSITIONS FOR SOLUBILIZING TISSUE - Tissue solubilizing compositions are provided. The compositions comprise 3-(decyl dimethyl ammonio) propane sulfonate and polyethylene glycol dodecyl ether, such as tetraethylene glycol dodecyl ether. The compositions may be useful to solubilize tissue, including skin, mucosal membrane, and other tissue. The compositions may be further useful to preserve and recover analytes contained within the solubilized skin, mucosal membrane, and other tissue.01-05-2012
20120004596Catheter for Use in Revascularization Procedures and Method of Using Same - A method of removing vascular blockage includes providing a catheter system. comprising an outer catheter, a cutting catheter having a serrated distal end, a bypass catheter, and a guidewire. In the catheter system, the bypass catheter is slidably disposed within the cutting catheter and the outer catheter. The method includes positioning a distal end of the catheter system at a proximal end of an occlusion located within a vessel and moving the bypass catheter through the occlusion so that a medicated treatment solution may be delivered through the bypass catheter to an area of the brain or other tissue served by the vessel blocked by the occlusion. Both during and after the delivery of medicated treatment solution to the blocked part of the vessel with the bypass catheter, the physician may engage the occlusion with the cutting catheter by moving the cutting catheter in a clockwise/counterclockwise or forward/backward direction within the outer catheter, cutting and then removing at least a portion of the occlusion from the vessel.01-05-2012
20120004597MEDICAL DEVICE FOR INJECTING FLUID INTO A BODY - The medical device (01-05-2012
20120004595DEVICES AND METHODS FOR CUTTING AND EVACUATING TISSUE - Various medical devices and methods for cutting and/or evacuating tissue are provided. The devices and methods may utilize a reciprocating mechanism or motor powered by suction from a vacuum source. The medical devices and methods may be used on tissue in various regions of a patient's body and for treating various conditions, e.g., for performing a polypectomy or discectomy.01-05-2012
20120004594METHODS OF TREATING DEGENERATIVE BONE CONDITIONS - Methods and articles of manufacture for treating patients with degenerative bone are provided. The methods are useful to improve bone quality in a localized area of a degenerative bone (e.g., osteopenic or osteoporotic bone), such as by improving BMD to be substantially similar to BMD in an average, healthy individual at the age of peak BMD. The methods can comprise forming a void in a localized area of the degenerative bone and filling the void with a bone regenerative material that causes generation of new, healthy, natural bone material. The articles of manufacture can comprise kits formed of various materials useful in the inventive methods for improving bone quality.01-05-2012
20120004593ANTISEPTIC BASED ON BISPYRIDINIUM ALKANES - An antimicrobially effective composition includes a) at least 0.15% by weight of bispyridinium alkane, b) at least 3.5% by weight of humectant and c) water. Upon dilution with water, the composition produces a solution with an osmolality of from 230 to 350 mOsmol/kg and is free from surfactant. It is used as an antiseptic and is suitable for use in a method for the disinfection of injured or uninjured skin of a human being or animal, preference being given to use in the case of newborns, in particular those born prematurely.01-05-2012
20120109045Encapsulation of Microbubbles Within the Aqueous Core of Microcapsules - The present invention includes a construct that comprises at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention also includes a pharmaceutical composition comprising a construct comprising at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention further includes a method of imaging a tissue or organ in a subject, a method of delivering a therapeutic cargo to a tissue or organ in a subject, and a method of treating a disease or disorder in a subject.05-03-2012
20120109044PREVENTION OF MYOCARDIAL INFRACTION INDUCED VENTRICULAR EXPANSION AND REMODELING - A method for direct therapeutic treatment of myocardial tissue in a localized region of a heart having a pathological condition. The method includes identifying a target region of the myocardium and applying material directly and substantially only to at least a portion of the myocardial tissue of the target region. The material applied results in a physically modification the mechanical properties, including stiffness, of said tissue. Various devices and modes of practicing the method are disclosed for stiffening, restraining and constraining myocardial tissue for the treatment of conditions including myocardial infarction or mitral valve regurgitation.05-03-2012
20080319374Post-occlusion chamber collapse canceling system for a surgical apparatus and method of use - A post-occlusion chamber collapse canceling system for a surgical apparatus that detects the breaking of occlusions by tissue fragments in the distal end of the aspiration path and produces a response consisting in a transitory blockage of the distal end the aspiration path to terminate the chamber collapse and a transitory venting of the aspiration line to relieve the vacuum, in a way that post-occlusion chamber collapses are cancelled.12-25-2008
20120310146SYSTEMS AND METHODS FOR VITRECTOMY - A system for conducting a vitrectomy includes: a gas source; a vitrector including a cutting mechanism that opens and closes according to a pressure at the vitrector; and a pulse-generating system receiving gas from the gas source and generating pulses at the vitrector. The pulses cause the pressure at the vitrector to vary according to a cycle, and the varying pressure at the vitrector causes the cutting mechanism of the vitrector to open and close. At a first time in the cycle, the pulse-generating system, raises the pressure at the vitrector to a maximum pressure. At a second time in the cycle, the pulse-generating system reduces the pressure at the vitrector to a minimum pressure that is greater than ambient, the pressure at the vitrector being maintained at least at the minimum pressure. The difference between the maximum pressure and minimum pressure is minimized to reduce gas consumption.12-06-2012
20120010560Modulated pulsed ultrasound power delivery system and method - A method and apparatus for delivering energy during a surgical procedure such as phacoemulsification is provided. The method and apparatus include applying energy during at least one pulsed energy on period, typically sufficient or intended to rapidly induce and beneficially employ transient cavitation. Applying energy during the pulsed energy on period comprises applying energy during a first high energy period, and applying energy during a second nonzero lower energy period.01-12-2012
20110166505PHACO THERMAL CONTROL APPARATUS AND METHOD - Control apparatus for an ultrasonic phacoemulsification handpiece utilizes flow rates and temperature measurements as well as power provided to a handpiece for calculating a matrix of power level duty cycle combination that would not generate sufficient heat to create a burn in eye tissue and either prevent operation of handpiece in the matrix or alert a surgeon of such use.07-07-2011
20110166503SYSTEM AND METHOD OF BONE PROCESSING - A system and method of processing bone is disclosed. A tissue separator is utilized to separate tissue comprising at least one of muscle, periosteum and connective tissue from bone in a safe, sterile and efficient manner. In one aspect, the particle reducer can include an impeller positioned with respect to a cutting surface on a drum. At least one of the impeller and the drum is rotated by a power source such that harvested tissue frictionally engages the cutting surface. In another aspect, a source of pressurized fluid can be directed at tissue to separate bone from non-bone tissue.07-07-2011
20110166502Apparatus and Method for Phacoemulsification - Apparatus and methods for phacoemulsification combine a phacoemulsification needle having an offset feature with a handpiece capable of producing longitudinal motion to create a hybrid phacoemulsification effect that is more efficient than conventional longitudinal handpiece-needle combinations and has been demonstrated under certain conditions to be more efficient than needles used with handpieces providing torsional motion. The phacoemulsification needle is of the type having a hollow passageway that terminates in a straight needle tip formed off-axis from the passageway, allowing the needle tip to move eccentrically when the needle is subjected to torsional or longitudinal vibratory motion. The tip may be flared or may be coextensive with the needle body. The tip may also be angled with respect to the needle body. The aspiration passageway formed through the needle body may be positioned or shaped to be off-axis from the needle body axis.07-07-2011
20120016292 APPARATUS, ARTICLE AND METHOD FOR REDUCING PAIN DURING SKIN PUNCTURING PROCEDURES - An instrument, article and method are provided for minimizing pain during administration by injection of a liquid, such as, an anesthetic. The instrument has a forward end. A lightpipe mounted freely for vibration projects out of the forward end. The article, a single use tip, is composed of a tip sleeve removably mounted on the forward end of the instrument and a tip member removably mounted on the projecting lightpipe to vibrate a preselected injection site on a human or animal. The tip sleeve and tip member are covered by an elastic overmold that enables the tip member to vibrate freely with respect to the tip sleeve and light from the lightpipe to illuminate the injection site. A vibration unit mounted in the instrument is coupled to the lightpipe. The method is carried out by imparting vibrations and illumination via the lightpipe to the tip member.01-19-2012
20100191179VASCULAR ACCESS PORTS AND RELATED METHODS - Ports for accessing a vessels within a patient include passageways that can guide needles or other access devices directly into the vessels. The ports can be implanted subcutaneously within a patient. Some ports may be used in the creation and use of vascular access buttonholes.07-29-2010
20120022435REMOVABLE TIPS FOR SKIN TREATMENT SYSTEMS - An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.01-26-2012
20120022434DISPOSABLE HANDHELD PHACOMORCELLATION DEVICE - Disposable handheld phacomorcellation devices and methods for removing lens fragments from an eye of a patient are disclosed. In one embodiment, the phacomorcellation device includes a stationary outer tubular cutting member and a rotatable inner cutting member positioned within the stationary outer tubular cutting member. The outer tubular cutting member and the rotatable inner cutting member each include at least one cutting port having at least one cutting edge. The at least one cutting edge of the outer tubular cutting member and the at least one cutting edge of the inner cutting member cooperate to form a bird beak cutting structure as the inner cutting member rotates with respect to the outer cutting member. The cutting port of the outer tubular cutting member can be substantially closed during rotation of the inner cutting member, thereby preventing lens fragments from floating toward a posterior region of the eye.01-26-2012
20110082414Ultrasound-enhanced stenosis therapy - Apparatus and methods for enhancing vascular stenosis therapy involve applying ultrasound energy to delivery of a therapeutic agent to enhance vessel wall penetration of the agent in an area of stenosis. In some embodiments, ultrasound energy and therapeutic agent application may be combined with angioplasty techniques and/or with blood flow protection devices to prevent dissipation of the therapeutic agent from the treatment site.04-07-2011
20120059310VIBRATION INDUCED IN VIVO SUBSTANCE TARGETING - A method for aggregating a substance in a localized region within a body of an animal comprises applying a vibration pattern that causes aggregation of the substance to the localized region within the body of the animal, introducing the substance and aggregating the substance in the localized region based upon application of the vibration pattern. The substance, which may be a drug, fluorescent dye, conjugate of the two or a smart probe, may aggregate to bone, specifically to the lumbar region of the spine. About two to about four times more substance may aggregate in the localized region of the body relative to a control where no vibration pattern is applied.03-08-2012
20120059309Fluid Delivery and Treatment Device and Method of Use - A medical device system is provided herein which has an elongated, flexible hollow member with an expandable infusion segment attached at the most distal end of the device. The device has a plurality of fluid infusion ports on the expandable infusion segment for delivering an intended fluid to a target site in a body lumen. Additionally, a method is provided herein for infusing an intended fluid to a target site within a body lumen.03-08-2012
20120157906VITRECTOMY PROBE WITH ADJUSTABLE CUTTER PORT SIZE - Vitrectomy probes and system related thereto are disclosed herein. The disclosure describes various example vitrectomy probes having an adjustable cutting port size. Various example features are described for adjusting the size of the cutting port. Further, the disclosure provides examples for adjusting the size of the cutter port while the vitrectomy probe is in operation.06-21-2012
20110092886MULTIPLE FREQUENCY PHACOEMULSIFICATION NEEDLE DRIVER - A system for performing an ocular surgical procedure is provided. The system includes a multiple frequency signal source, a configurable tuned output filter connected to the multiple frequency signal source, and a multiple frequency ultrasonic handpiece. The multiple frequency signal source operates at a first frequency and is configured to drive the configurable filter and the multiple frequency ultrasonic handpiece at the first frequency. The multiple frequency signal source operates at a second frequency and is configured to drive the configurable filter and the multiple frequency ultrasonic handpiece at the second frequency, and the design addresses third harmonic frequency issues for the multiple frequency ultrasonic handpiece. Switchable passive components, such as inductors, resistors, and/or capacitors may be employed in the configurable tuned output circuit, or alternately multiple similar circuits may be employed. Alternately, a multi-tap transformer may be provided.04-21-2011
20110092885Phacoemulsification Needle Tip With Bumps - A phacoemulsification needle has at least one grouping of surface protuberances formed on the tip inner surface, outer surface, or both. The protuberance groupings comprise three-dimensional protuberances of varying selected geometric shapes positioned proximate the lip of the phacoemulsification needle tip and provide surfaces to increase the efficacy of the phacoemulsification process.04-21-2011
20110092889THERAPEUTIC DEVICE - A device for treating a passage in a body part, said device having a flexible elongate body comprising a leading segment that is inserted into an opening to the passage and passed therethrough until it exits the passage and a cleaning segment that follows the leading segment through the passage and debrides the passage as it is forced therethrough.04-21-2011
20110092888ROTATIONAL ALIGNMENT OF FLUID DELIVERY DEVICE - A device configured for use in an ocular surgical procedure is provided. The device, such as a sleeve or a needle, includes a proximal portion, a distal portion including at least one fluid opening formed at a predetermined orientation, and at least one visual marking provided at the proximal portion at a predetermined marking orientation relative to said predetermined orientation. The visual marking or markings provide a visual indication of orientation of the fluid opening when the device is employed in the ocular surgical procedure.04-21-2011
20110092887METHOD FOR PROGRAMMING FOOT PEDAL SETTINGS AND CONTROLLING PERFORMANCE THROUGH FOOT PEDAL VARIATION - The present invention pertains to programming a foot pedal and switches located therewith that is used with a medical device and/or medical device system. A user may select any switch or directional movement available on the foot pedal for programming by activating the switch and/or moving a treadle located on the foot pedal or by selecting a foot pedal feature on a display. The programming options available for the selected switch or directional movement are displayed on the display screen. Using the foot pedal, the display screen, voice command or combinations thereof, the user can navigate through different options to select one or more options and confirm the chosen option(s) for the particular switch or directional movement. The control and feel of the movement of the treadle and/or switch provides the user with the ability to program custom settings that suit the user's foot position(s) and/or particular style of surgery.04-21-2011
20100152646Intravitreal injection device and method - A coordinated cutting and spreading mechanism within a syringe dilator sub-assembly is applied to an eye surface during an intravitreal injection to provide an access window free of the conjunctival layer and through which an injection needle can be inserted. The system and method comprises a dilator sub-assembly including both the cutting and spreading mechanism and the intravitreal injection needle, for use with a conventional syringe. The dilator sub-assembly includes a number of projections to secure points of the surface of the conjunctival layer, a cutting member to incise the conjunctival layer, and at least one deflectable projection to move during the intravitreal injection, spreading the incision, and creating a window opening in the conjunctival layer through which the intravitreal injection needle then enters. Upon removal of the device from the injection site, the deflectable projection is released and the window opening in the conjunctival layer is closed.06-17-2010
20120071812Methods and Systems for Submucosal Implantation of a Device for Diagnosis and Treatment with a Therapeutic Agent - Instruments, systems, implants, and methods are provided for performing submucosal medical procedures in a desired area of the digestive tract using endoscopy. Instruments include a safe access needle injection instrument, a submucosal tunneling instrument, a submucosal dissection instrument, and a mucosal resection device. A submucosal implant device for diagnosing and treating disorders of the body may be implanted. A passive submucosal implant device may take the form of a drug delivery depot in which a therapeutic agent within the depot elutes from the depot according to a predetermined elution profile. An active submucosal implant device may take the form of a drug delivery device that incorporates a self-contained diagnostic system to determine the appropriate delivery time and dosage of a therapeutic agent to be administered.03-22-2012
20120157909VITRECTOMY PROBE WITH ADJUSTABLE CUTTER PORT SIZE - Vitrectomy probes and system related thereto are disclosed herein. The disclosure describes various example vitrectomy probes having an adjustable cutting port size. Various example features are described for adjusting the size of the cutting port. Further, the disclosure provides examples for adjusting the size of the cutter port while the vitrectomy probe is in operation. Some implementations disclosed herein include a piezoelectric element operable to adjust a position of a stroke limiter to define a size of the cutter port.06-21-2012
20120157908VITRECTOMY PROBE WITH ADJUSTABLE CUTTER PORT SIZE - Vitrectomy probes and system related thereto are disclosed herein. The disclosure describes various example vitrectomy probes having an adjustable cutting port size. Various example features are described for adjusting the size of the cutting port. Further, the disclosure provides examples for adjusting the size of the cutter port while the vitrectomy probe is in operation.06-21-2012
20120157907VITRECTOMY PROBE WITH ADJUSTABLE CUTTER PORT SIZE - Vitrectomy probes and system related thereto are disclosed herein. The disclosure describes various example vitrectomy probes having an adjustable cutting port size. Various example features are described for adjusting the size of the cutting port. Further, the disclosure provides examples for adjusting the size of the cutter port while the vitrectomy probe is in operation.06-21-2012
20100241060SURGICAL DEVICES AND METHODS - Surgical devices and methods are described. The devices are for implanting fluidic material in a patient's eye and comprise a nozzle and a housing having a slide and a bellows. The bellows is adapted to undergo compression or decompression. The surgical procedures make use of the surgical devices and include a tissue translocation surgical procedure, a retinal implantation surgical procedure, and a corneal transplantation surgical procedure.09-23-2010
20100094199System and method for modulated surgical procedure irrigation and aspiration - A method and apparatus for performing modulated fluid delivery and aspiration during a surgical procedure such as phacoemulsification is provided. The method and apparatus include delivering fluid and/or aspirating fluid in a modulated or pulsed manner during a surgical procedure, including applying fluid and/or aspirating fluid in connection with ultrasonic energy at a level and for a time period sufficient to induce transient cavitation. Fluid may be applied and/or aspirated at a timing sequence and duty cycle similar to or different from application of ultrasonic energy delivery.04-15-2010
20100094198SYSTEMS AND METHODS FOR TIGHTENING OPHTHALMIC SURGICAL NEEDLES - An ophthalmic surgery system includes a pump for generating fluid flow during ophthalmic surgery, a handpiece interface for providing control of a surgical handpiece, and a power wrench assembly for coupling to an ophthalmic surgical needle. The power wrench assembly is configured to rotate the ophthalmic surgical needle relative to the surgical handpiece until torque applied to the ophthalmic surgical needle is within a desired torque range.04-15-2010
20120123320APPARATUS AND METHOD FOR TREATING BODY TISSUES WITH ELECTRICITY OR MEDICAMENTS - A therapeutic device and therapeutic method for delivering electrical energy or medicament to a body tissue or organ utilizing ultrasonic vibration to cause a device implanted in the body tissue or organ to be treated to discharge and electrical current or medicament to the target area.05-17-2012
20120123321Ultrasonic dispersion of compositions in tissue - Therapeutic agents, diagnostic agents and other compositions can be effectively delivered to target tissues using ultrasonic dispersion. For example, a therapeutic agent in solution may be injected subcutaneously in the vicinity of a target tissue in a patient. External ultrasound is used to disperse the therapeutic agent in the target tissue. The disclosed methods provide increased concentrations of therapeutic agents in tissue relative to traditional delivery methods, thereby improving therapeutic outcomes while reducing costs. In addition the methods can be used to deliver effective concentrations of therapeutic agents to tissues with limited blood supply.05-17-2012
20120165724HYDRAULIC VITRECTOMY PROBE - Hydraulic vitrectomy probes and methods and systems associated therewith are discussed. Example hydraulic vitrectomy probes may include a pressure multiplier that is operable to output a hydraulic pressure at a multiple of a received pneumatic pressure. Because of the incompressible nature of liquid, hydraulic vitrectomy probes are, among other things, more responsive, may be operated at higher cutting rates, provide improved patient safety, and have a form factor (e.g., size and/or shape) that may be more easily maneuvered by a surgeon.06-28-2012
20120165725DISSECTION HANDPIECE WITH ASPIRATION MEANS FOR REDUCING THE APPEARANCE OF CELLULITE - A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece. The device and method cut the fibrous structures under the skin that cause cellulite at an angle substantially parallel to the surface of the skin and replace these structures with a non-cellulite forming structure by deploying a highly fibrous mesh through a single needle hole to create a highly fibrous layer directly or through wound healing processes. A tool is provided to aspirate excess fluid and tissue from the treatment area.06-28-2012
20120220925REDUCED-PRESSURE TREATMENT SYSTEMS AND METHODS EMPLOYING DEBRIDEMENT MECHANISMS - Reduced-pressure treatment systems and methods are disclosed that employ debridement mechanisms to remove unwanted tissue. In one instance, a reduced-pressure treatment system for treating a tissue site on a patient includes a manifold member for distributing reduced pressure to the tissue site, a support member for disposing proximate the tissue site and the manifold, and a debridement mechanism coupled to the support member. The debridement mechanism is for debriding the tissue site. The system further includes a sealing drape for placing over the tissue site and manifold member. The sealing drape is operable to form a fluid seal over the tissue site and manifold member. The system also includes a reduced-pressure subsystem for delivering a reduced pressure to the sealing drape. The system may further include a chemical-debridement subsystem. Other systems, manifolds, and methods are disclosed.08-30-2012
20120316490SURGICAL SYSTEM FOR DAMPENING VIBRATIONS BETWEEN A CANNULA AND A SURGICAL INSTRUMENT - A surgical system 12-13-2012
20100204643Ultrasound-assisted drug-delivery method and system based on time reversal acoustics - An ultrasound beacon is incorporated into a needle of a drug delivery system utilizing high intensity ultrasound energy during certain cancer treatments. The beacon is configured to generate a electrical feedback signal in response to an initial ultrasound signal sent by an ultrasound transmitter. The electrical feedback signal is then sent along two electrical conductors of the needle and further over a cable back to the electronic unit. The feedback signal is then used to generate high intensity focused ultrasound using time-reversal acoustics principles. Therapeutic application of the system of the invention includes applying high intensity focused ultrasound at the site of drug delivery to enhance local tissue uptake of injected medication.08-12-2010
20100204642CATHETER WITH MULTIPLE ULTRASOUND RADIATING MEMBERS - A method of delivery ultrasonic energy and a therapeutic compound to a treatment site and an ultrasonic catheter system are disclosed. The method comprises providing a catheter with a plurality of ultrasound radiating members, wherein the plurality of ultrasound radiating members are allocated into electrical groups comprising more than one ultrasound radiating member. The method further comprises independently driving each group of ultrasonic radiating members, and delivering the therapeutic compound through the catheter to the treatment site.08-12-2010
20100204641Apparatus for Applying Wound Treatment Material Using Tissue-Penetrating Needles - A surgical apparatus is provided including a disposable loading unit selectively operatively engagable within a distal end of a first half-section; and a wound treatment material applicator assembly for delivering wound treatment material to the target surgical site. The disposable loading unit includes a cartridge; a plurality of deployable needles supported within the cartridge, wherein each needle includes a lumen extending therethrough and at least one hole formed in an outer periphery thereof; and an actuation member translatably disposed within the cartridge for delivering a driving force to each needle to deploy the needles from the cartridge. The applicator assembly includes a first and second reservoir supported on the distal end of a respective first and second half-section; and a source of wound treatment material in fluid communication with each reservoir.08-12-2010
20110184337Methods and devices for denervation - Various delivery devices are described to deliver an agent locally to the renal nerves. The delivery devices are positioned in the renal artery and penetrate into the wall of the renal artery to deliver the agent to the renal nerves. The delivery devices may be used to deliver the agent according to longitudinal position, radial position, and depth of the renal nerves relative to the renal artery. In addition, various methods are described to denervate, modulate, or otherwise affect the renal nerves and other neural tissue. Also, various agents are described to denerve, modulate, or otherwise affect the renal nerves and other neural tissue.07-28-2011
20120083728PHACOEMULSIFICATION HAND PIECE WITH INTEGRATED ASPIRATION PUMP - An ophthalmic surgical hand piece comprises a driver coupled to a horn. The horn is coupled to a needle. An aspiration pump is integral with the hand piece and is located close to the needle. A rigid length of aspiration line is located between the aspiration pump and the needle. An optional pressure sensor is located between the aspiration pump and the needle as well.04-05-2012
20120083727DRUG DELIVERY BLADE AND METHODS FOR DELIVERING A DRUG DEPOT TO A TARGET SITE - A drug delivery blade for delivering a drug depot to a treatment site in a patient is disclosed. The drug delivery blade includes a shaft defining a longitudinal axis of the blade, a lumen that extends longitudinally from a proximal end of the shaft to a distal end of the shaft, a first beveled cut that forms a sharpened tip at the distal end of the shaft, and a flared portion near the distal end of the shaft. The flared portion of the blade includes two radially-extending blade segments having sharpened leading edges that allow the drug delivery blade to cut tissue when the blade is advanced toward a treatment site. Methods of using the drug delivery blade are also disclosed.04-05-2012
20120172786MULTI-SLEEVED SURGICAL ULTRASONIC VIBRATING TOOL SUITED FOR PHACOEMULSIFICATION IN A MANNER THAT PREVENTS THERMAL INJURY TO OCULAR TISSUE - A multi-sleeve handpiece for performing phacoemulsification with a vibratory, ported needle and for cooling an exterior of an incision. The vibratory, ported needle breaks up and aspirates broken eye tissue. The handpiece has at least one inner sleeve that guides irrigation fluid to the eye and/or reduces friction between the vibrating tool and the surrounding rigid sleeve or tissues. The handpiece has an outer, cooling sleeve that is concentric with the inner sleeve and the needle and whose distal end has peak and valley formations. The cooling sleeve is collapsible to engage incision tissue with the peak formations and allow the cooling fluid to flow across the valley formations to cool the tissue via heat transfer.07-05-2012
20120220924REDUCED-PRESSURE TREATMENT SYSTEMS AND METHODS EMPLOYING DEBRIDEMENT MECHANISMS - Reduced-pressure treatment systems and methods are disclosed that employ debridement mechanisms to remove unwanted tissue. In one instance, a reduced-pressure treatment system for treating a tissue site on a patient includes a manifold member for distributing reduced pressure to the tissue site, a support member for disposing proximate the tissue site and the manifold, and a debridement mechanism coupled to the support member. The debridement mechanism is for debriding the tissue site. The system further includes a sealing drape for placing over the tissue site and manifold member. The sealing drape is operable to form a fluid seal over the tissue site and manifold member. The system also includes a reduced-pressure subsystem for delivering a reduced pressure to the sealing drape. The system may further include a chemical-debridement subsystem. Other systems, manifolds, and methods are disclosed.08-30-2012
20120172787DRUG DELIVERY MEDICAL DEVICE - Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on the substrate, wherein the coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one active biological agent and optionally, one or more pharmaceutical carrying agents; wherein substantially all of pharmaceutical agent and/or active biological agent remains within the coating and on the substrate until the implantable device is deployed at an intervention site inside the body of a subject and wherein upon deployment of the medical device in the body of the subject a portion of the pharmaceutical agent and/or active biological agent is delivered at the intervention site along with at least a portion of the polymer and/or a at least a portion of the pharmaceutical carrying agents.07-05-2012
20120215157Device, Methods, and Control for Sonic Guidance of Molecules and Other Material Utilizing Time-Reversal Acoustics - The present invention provides for a method of controlling mass movement of fluid material within a field of interest comprising using time reversal acoustic focusing. The time reversal acoustic focusing can be is used for simultaneous spatial and temporal focusing of acoustic energy to control the duration of localization and/or direction of movement of material within tissue or liquid within tissue. Both delivery of material and persistence with respect to target locations can be enhanced by focusing of sonic waveforms or transmissions towards targeted areas in a field of interest, such as within a patient.08-23-2012
20100049118DRUG INJECTING DEVICE - There is provided a drug injecting device including a drug feeding unit (02-25-2010
20100022945IMPLANTABLE DRUG DELIVERY SYSTEM - An implantable medicament delivery device includes a core body which further includes a single basin or multiple smaller basins for containing a drug or a medicament. Each basin is covered by a screen. The implantable drug delivery device is placed within the body of an animal, and the drug is allowed to diffuse through the holes in the screen to provide treatment of a disease or condition.01-28-2010
20100022944METHOD AND APPARATUS FOR TREATING AN ACUTE MYOCARDIAL INFARCTION - A method and apparatus for treating an acute myocardial infarction is provided. The apparatus comprises an ultrasound catheter that can be inserted into the esophagus to deliver ultrasound energy to the heart and coronary vasculature. The ultrasound energy can enhance the effect of an intravenously administered thrombolytic drug on a blood clot within the coronary vasculature. The ultrasound catheter can have a means for promoting acoustic coupling with the esophagus and a means for preventing or reducing aspiration of fluids into the lungs.01-28-2010
20100022943Hydrodynamic Thrombectomy Catheter - A catheter apparatus for removing an obstruction within a body lumen includes an elongate tubular shaft defining a lumen and a flexible membrane that fluidly seals the distal end of the tubular shaft. At least one cutter member is attached to and distally extends from the flexible membrane. An actuating mechanism is operatively connected to a proximal end of the tubular shaft. The actuating mechanism displaces a fluid disposed within the lumen of the tubular shaft in such a manner that the fluid oscillates the flexible membrane and the cutter member attached thereto. Accordingly, the catheter apparatus uses pulsatile fluid flow through the tubular shaft to transmit energy from the driving mechanical at the proximal end of the catheter apparatus to the flexible membrane at the distal end of the catheter apparatus. The transmitted energy causes the cutting member to oscillate and break up a target blood clot.01-28-2010
20110098634TOPICAL ANESTHETIC AND ANTISEPTIC DISPENSING DEVICE - Embodiments of the present invention provide a topical anesthetic and antiseptic dispensing device article of manufacture. In an embodiment of the invention, the article of manufacture includes a penetrating instrument including an elongated body with first and second distal end such that at least one of the distal ends includes a penetrating edge. By way of example, the penetrating instrument can be a syringe, an IV catheter needle assembly, a pressurized tube holder configured with a needle for blood draw, or a scalpel, to name a few possibilities. The article of manufacture further includes an attachment connector to couple the container to the housing of the penetrating instrument, where the attachment connector includes a circular connector body and a connector arm, the connector arm affixed to a spray housing of the dispensing device. The container provides at least one chamber. Finally, the article of manufacture includes a nozzle connected to the container and configured to dispense pressurized content of the container responsive to activating a trigger assembly communicating with the nozzle.04-28-2011
20100010420SYSTEM AND METHOD FOR TREATING SUBCUTANEOUS TISSUES - An apparatus and method for treating subcutaneous tissues using acoustic waves in the range of low acoustic pressure ultrasound waves is disclosed. The method includes injections of enhancing agents, wherein disruption of subcutaneous tissues and subcutaneous cavitational bioeffects are produced by ultrasound waves having a power that will not produce tissue cavitation in the absence of the enhancing agents. The apparatus and method of use is useful for treatment of subcutaneous abnormalities including cellulite, lipomas, and tumors.01-14-2010
20100010419Phacoemulssification Needle Tips - A phacoemulsification needle has tip geometries configured to operate efficiently in both the longitudinal and torsional modes. In one variation, the needle tip has a sharpened edge formed on at least a portion of the needle lip. In other variations the lip geopmetry is selected to create cutting surfaces in both the torsional and longitudinal directions.01-14-2010
20100056986REMOVABLE ADAPTER FOR PHACOEMULSIFICATION HANDPIECE HAVING IRRIGATION AND ASPIRATION FLUID PATHS - Current phacoemulsification handpieces require rigorous cleaning after each procedure because the aspiration and irrigation pathways for fluids are integral to the handpiece. According to the present invention, a removable horn extension and nosecone may be used with a phacoemulsification handpiece to allow for disposable fluid pathways exterior to the handpiece. This will reduce the cleaning time and effort, reduce cross-contamination, and increase the lifespan of the handpiece. Furthermore, the current invention allows different horn extensions to be used to excite different motions at the tip of the handpiece, depending on the preference of the surgeon.03-04-2010
20120226221VACUUM SENSE CONTROL FOR PHACO PULSE SHAPING - A method and apparatus for precisely controlling particle movement relative to a phacoemulsification needle tip is provided. The design monitors actual vacuum present and calculates a pulse shape amplitude waveform proportional to the amount of measured vacuum. An increase in vacuum indicates that the handpiece/needle is becoming occluded by a large particle. The present design determines whether additional power is required to bump or move a large particle away from the needle tip. The present design may employ a control loop that senses and continuously monitors vacuum. The design may dynamically vary the amount of ultrasonic energy delivered to the surgical area in response to the observed actual vacuum, and can actively vary the amount of power delivered to the surgical area based on the size of the particle and the resultant vacuum realized.09-06-2012
20120226220SHIELDABLE UNIT DOSE MEDICAL NEEDLE ASSEMBLIES - A shieldable unit dose assembly includes a needle holding member, a safety shield member disposed around the needle holding member, and a unit dose needle including a hub which is connected to the needle holding member. The needle holder member includes a male tapering surface and the hub of the unit dose needle includes a female tapering surface for connection therebetween. The unit dose needle includes a solid elongated unit dose needle having a patient end for containing and administering a unit dose of a vaccine. The telescoping safety shield member is disposed around the needle holding member, and is axially movable from a non-shielding position surrounding at least a portion of the needle holding member to a telescoped shielding position encompassing the patient end of the unit dose needle. The safety shield member may be locked into the shielding position.09-06-2012
20090018489METHOD OF TREATING WOUNDS BY CREATING A THERAPEUTIC COMBINATION WITH ULTRASONIC WAVES - A method of treating infected wounds utilizing ultrasonic vibrations to mix different materials together as to create a therapeutic combination is disclosed. The materials are mixed by passing them through an ultrasound horn vibrating in resonance, having an internal chamber. As the materials pass through the internal chamber, ultrasonic vibrations emanating from and/or echoing off the various walls of the chamber mix the materials into a potentially therapeutic combination. Ultrasonic vibrations emanating from the radiation surface of the horn may be used to spray the created therapeutic combination onto the area of the body to be treated.01-15-2009
20090018488Method of Priming a Surgical System - A method of priming a surgical system that includes pulling a very high vacuum and then cycling fluid through the system as a fluid pulse. These steps can be repeated a number of times to help ensure that residual entrained air is removed from the system.01-15-2009
20090018490Retractable ultrasonic endoscopic aspirator - A surgical instrument comprising a sleeve, a electro-mechanical transducer containing a hollow passage for producing mechanical vibrations in response to a magnetic field, an ultrasonic horn mechanically connected to the transducer, containing a hollow passage communicating with that in the transducer, for amplifying the produced vibration such that dissection of biological tissue is produced and a tip having a hollow passage, mechanically connected to the horn and whose passage communicates with that in the horn, for contacting such tissue, connection of the passage to a source of vacuum and a sheath connected to the instrument and surrounding the tip and horn, with a connection to a source of irrigating fluid and a structure for mounting the transducer and horn within the sleeve permitting retracting and extension of the transducer and horn within and with respect to the sheath. The transducer, horn and tip are immersed in the irrigating solution. The instrument may also include a telescope for viewing the tissue contacting site and provision for electrifying the tip with electro-cauterizing current as well as provision for the use of endo-laser fulguration of the site.01-15-2009
20120232466Ophthalmosurgical Measuring Device - An ophthalmosurgical measuring device (09-13-2012
20080300531Single infusion port apparatus and method for phacoemulsification - A phacoemulsification apparatus having a single infusion port oriented toward the posterior of the eyeball and away from the cornea may be used in a process for removing cataracts in patients suffering from Fuch's Dystrophy. A method for using a phacoemulsification apparatus having a single infusion port oriented toward the posterior of the eyeball and away from the cornea to remove cataracts in patients suffering from Fuch's Dystrophy is also described.12-04-2008
20110004149PHACOEMULSIFICATION HOOK TIP - In various embodiments, a phacoemulsification cutting tip with a straight shaft and an angled portion off of the straight shaft may include a hook on the angled portion to move an axis of rotation of the cutting tip closer to alignment with an extended centerline of the shaft. The cutting tip may be configured to torsionally rotate back and forth on an axis perpendicular to a centerline of the shaft (e.g., rotation around a y-axis). In some embodiments, lateral vibrations (e.g., side to side along an x-axis or z-axis perpendicular to the y-axis) that result from torsional rotation around the y-axis in a cutting tip without the hook may be reduced through use of the hook to balance the otherwise eccentrically weighted hook.01-06-2011
20120238946ULTRASOUND CATHETER AND METHODS FOR MAKING AND USING SAME - Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and, in some embodiments, a guidewire tube extending through the lumen. A distal head for disrupting occlusions is coupled with the distal end of the ultrasound transmission member and is positioned adjacent the distal end of the catheter body. Some embodiments include improved features such as a bend in the catheter body for enhancing positioning and/or advancement of the catheter.09-20-2012
20120265123Central Nervous System Drain - The invention provides a method and apparatus for maintaining central nervous system drain patency. Ultrasound energy delivered through the drain dissolves the hemorrhage and debris occluding the drain lumen and ports.10-18-2012
20120330221TISSUE PROSTHESIS AND METHOD OF, AND EQUIPMENT FOR, FORMING A TISSUE PROSTHESIS - A tissue prosthesis 12-27-2012
20110046543METHOD AND DEVICE FOR VEIN ABLATION - A method for collapsing a target vein in a patient. The method comprises providing an intravascular irritation element having a plurality of mechanical irritating objects, inserting the intravascular irritation element into a venous lumen of a target vein, and irritating the target vein by moving the plurality of mechanical irritating objects in contact with the inner surface thereof, thereby triggering a collapse of said target vein.02-24-2011
20120271223Central Nervous System Drain - The invention provides a method and apparatus for maintaining central nervous system drain patency. Ultrasound energy delivered through the drain dissolves the hemorrhage and debris occluding the drain lumen and ports.10-25-2012
20120323166PHACOEMULSIFICATION IRRIGATION SLEEVE WITH AN ALIGNMENT MARK - A phacoemulsification irrigation sleeve 12-20-2012
20110160645Cryo Activated Drug Delivery and Cutting Balloons - Physical property changes in materials between body temperature and a cryotreatment temperature are used to benefit auxiliary functional structures on a cryotherapy device. The auxiliary functional structures may be drug delivery coatings, cutting balloon blades, balloon stiffeners or force concentrators.06-30-2011
20110238003METHOD FOR SYSTEMIC DRUG DELIVERY THROUGH THE NAIL - A method for systemically delivering a pharmaceutical composition to a human or animal, said method comprising forming an orifice in a nail of a human or animal by means of a laser-based device and applying a pharmaceutical composition in the orifice, wherein said method provides a controlled release of the pharmaceutical composition.09-29-2011
20120089082SHEATH FOR USE WITH AN ULTRASOUND ELEMENT - An apparatus for delivering ultrasound energy and a drug solution to a treatment site in a vessel is disclosed. The apparatus includes an elongate, hollow sheath having a distal opening and an energy delivery section at least partially constructed from a material that transmits ultrasound energy. The apparatus also includes a drug delivery lumen positioned along at least a portion of the sheath, the drug delivery lumen having at least one drug delivery port within the energy delivery section. The apparatus further includes an elongate body having an ultrasound element, the elongate body configured to be movably positioned within the sheath, such that ultrasonic energy can be transmitted from the ultrasound element through the energy delivery section.04-12-2012
20120089081Piezoelectric element driver - The invention teaches a palm-held massage device which includes a driver that drives one or more massage elements which provides massage vibrations in one or more ultrasonic and subsonic frequencies, a controller that provides commands to the driver, a signal generator that provides frequency references to the driver, a power supply coupled to a contactless charger, and a specimen dispensing system.04-12-2012
20120089080TISSUE REMOVAL DEVICES, SYSTEMS AND METHODS - A tissue removal device includes a cannula that can aspirate tissue under a vacuum applied in the cannula, and a hermetically sealed fluid regulator in fluid communication with the cannula that generates vacuum pulses according to a controllable pulse rate and flow rate. The tissue removal device may also have a vacuum conduit having two or more conduit sections where the inner diameter of an upstream conduit section is smaller than the inner diameter of a succeeding conduit section. A device is also provided for applying an elastic membrane to an open end of the cannula to allow a user to remove any remaining cortical material after cataract material has first been removed from the eye by vacuum pressure applied in the cannula.04-12-2012
20120089079Ultrasonic device with integrated specimen dispenser - This application teaches a novel ultrasonic skin care device with a built-in specimen containment and a dispensing mechanism to enable easy application of the specimen for hygiene operation of the device for skin beautification purpose. The device provides portability for usage anywhere and anytime and provides a flexibility of multi-purpose skin care treatment with a unique design of multiple specimen containment structures.04-12-2012
20110282270Instrument for Debriding Tissue and Applying Therapeutic Cells - A tissue treatment device comprises a housing having a chamber that receives a treatment fluid mixture of tissue morsels and a scaffold material. A debriding shaft including a plurality of cutters is coupled with the housing. The debriding shaft extends proximally within the chamber and extends distally from the end of the housing. The debriding shaft is inserted within a treatment site such as a fistula tract and is rotated and reciprocated such that the debriding shaft removes tissue cells along the site. The site is flushed with saline or other irrigating fluid followed by application of the treatment fluid mixture. The chamber of the housing comprises agitators positioned adjacent the debriding shaft. The treatment fluid mixture passes through the chamber of the housing along and between the outer surface of the debriding shaft and the agitators for thorough mixing before exiting the device at the treatment site.11-17-2011
20110319812SYSTEM AND METHOD FOR PAIN REDUCTION DURING SKIN PUNCTURE AND BREAKABLE TIP THEREFOR - An instrument, article and method are provided for minimizing pain during administration by injection of a liquid, such as, an anesthetic. The instrument has a forward end. A lightpipe mounted freely for vibration projects out of the forward end. The article, a single use tip, is composed of a tip sleeve removably mounted on the forward end of the instrument and a tip member removably mounted on the projecting lightpipe to vibrate a preselected injection site on a human or animal. The tip sleeve and tip member are covered by an elastic overmold that enables the tip member to vibrate freely with respect to the tip sleeve and light from the lightpipe to illuminate the injection site. The overmold of the single use tip is torn during removal of the single use tip from the instrument.12-29-2011
20110319811COMBINATION THERAPY WITH CRYOSURGERY AND LOW DOSAGE STRENGTH IMIQUIMOD TO TREAT ACTINIC KERATOSIS - The present invention is directed to the use of complementary or combination lesion-directed therapy, such as cryosurgery, and field-directed therapy, such as low dose imiquimod topical therapy with short durations, in combination to treat actinic keratosis (“AK”). In carrying out the present invention, the lesion-directed and field-directed therapies may be applied sequentially or concomitantly, in accordance with the present invention. The novel complementary or combination AK therapy contemplated by the present invention: (1) significantly improves clearance of cryosurgery-treated Aks; (2) treats subclinical AK lesions; (3) treats those visible AK lesions in excess of that cryosurgery can actually treat in a single treatment due to, e.g., patient tolerance, provider treatment limits and/or cryosurgery cost to the patient; and (4) enhances sustained clearance overall, as compared to mono AK lesion-directed therapy.12-29-2011
20110319810Curved Infusion Sleeve - An infusion sleeve, infusion sleeve assembly, and method of making the same are disclosed. An exemplary infusion sleeve assembly may include a tubular body and a tip inserted into the body. The tubular body may include an insertion end and an attachment end. The insertion end may define a tip aperture and a first fluid aperture adjacent the tip aperture, while the attachment end may be configured to be secured to a surgical tool for fluid exchange therewith. The tubular body includes a curved portion between the insertion end and attachment end such that a first axis of the insertion end is angled relative to a second axis of the attachment end. Further, the tubular body may define a substantially smooth surface throughout the curved portion.12-29-2011
20120330223ENERGY BASED HYPERHIDROSIS TREATMENT - A method and system for energy-based (e.g., ultrasound treatment and/or other modalities) of sweat glands are provided. An exemplary method and system for targeted treatment of sweat glands can be configured in various manners, such as through use of therapy only, therapy and monitoring, imaging and therapy, or therapy, imaging, and monitoring, and/or through use of focused, unfocused, or defocused ultrasound (or other energy) through control of various spatial and temporal parameters. As a result, ablative energy can be deposited at the particular depth at which the aberrant sweat gland population is located below the skin surface.12-27-2012
20120330222METHODS FOR TREATMENT OF HYPERHIDROSIS - Methods for ultrasound treatment of hyperhidrosis are provided. Various methods and systems for targeted treatment of sweat glands can be configured in various manners, such as through use of therapy only, therapy and monitoring, imaging and therapy, or therapy, imaging, and monitoring, and/or through use of focused, unfocused, or defocused ultrasound through control of various spatial and temporal parameters. As a result, thermal and/or ablative energy can be deposited at the particular depth at which the sweat gland population is located below the skin surface. Ultrasound and non-ultrasound treatments for hyperhidrosis are provided.12-27-2012
20120330220COLLECTION AND FILTRATION VIA SUCTION OF BIOLOGICAL MATERIAL DURING SURGICAL PROCEDURE - A method for collecting and filtering biological material from blood and other fluids during a surgical procedure includes: attaching a first cover including a suction port and an intake port to a collection trap; attaching a suction source to the suction port; attaching an instrument to the intake port, through which blood and tissue are suctioned and received into the collection trap; filing the collection trap with blood and tissue; removing the collection trap from the first cover; attaching a second cover to the collection trap in place of the first cover, the second cover including a suction port and a plunger, the plunger including a press head having a screen portion permitting blood and other fluids to pass; attaching a suction source to the suction port of the second cover; separating the blood from the tissue by deploying the plunger; and drawing off the blood through the suction port.12-27-2012
20120289889ULTRASOUND SYSTEM - A catheter system for delivering ultrasonic energy to a treatment site within a body lumen, the catheter comprises a tubular body having a proximal end, a distal end and an energy delivery section positioned between the proximal end and the distal end and a plurality of ultrasound radiating members in the energy delivery section. The plurality of ultrasound radiating members are allocated into electrical groups comprising more than one ultrasound radiating member. Members of one electrical group are spatially interdigitated with members of another electrical group.11-15-2012
20100168649MICROVASCULAR OBSTRUCTION DETECTION AND THERAPY - A method of detecting and treating a microvascular obstruction is provided. In one embodiment, a catheter is provided for both detecting the microvascular obstruction and treating or removing the obstruction.07-01-2010
20100168648System and method for transfetal (amnion-chorion) membranes transport - The invention provides a system and method for trans-fetal membranes transport. A source of ultrasound sonication is used to deliver ultrasound sonication to fetal membranes to enhance the permeability of the fetal membranes of a gestational sac. In one embodiment, a device is used to collect substances transported from the interior of the gestational sac to the exterior of the gestational sac, such as amniotic or coelomic fluid. In another embodiment a device is used to deliver one or more substances, such as a drug, to an external surface of the fetal membranes.07-01-2010
20100130915APPLICATION OF VACUUM AS A METHOD AND MECHANISM FOR CONTROLLING EYE CHAMBER STABILITY - A phacoemulsification system for operating a surgical handpiece having a handpiece; an irrigation fluid source for supplying irrigation fluid to the eye; an aspiration source coupled to the handpiece in order to aspirate the irrigation fluid from the eye through the handpiece; and a controller for controlling a vacuum in the handpiece, the controller comprising: a sensor for sensing the vacuum in the handpiece; an occlusion parameter, the occlusion parameter being a vacuum level corresponding to an occlusion of the handpiece or a flow rate corresponding to an occlusion of the handpiece; a maximum allowable vacuum level in the handpiece, the maximum allowable vacuum level having at least a first predetermined level; and a trigger value that is set based in part on the occlusion parameter.05-27-2010
20110160647Angioplasty Balloon Catheter with Active Delivery Medicament(s) Using Ultrasonic Means - The present disclosure relates to active drug eluting angioplasty balloon which utilizes ultrasonic energy to facilitate the release of the bioactive drug thereby avoids many of the drawbacks of prior art drug eluting devices.06-30-2011
20110160646MICRO-BURST ULTRASONIC POWER DELIVERY - Phacoemulsification apparatus includes a phacoemulsification handpiece having a needle and an electrical system for ultrasonically vibrating said needle along with a power source for providing pulsed electrical power to the handpiece electrical system. Irrigation fluid is provided to the handpiece needle and aspirating fluid is removed from the handpiece needle. A determination of a voltage current phase relationship of the provided electrical power is made and in response thereto a control system varies a power level duty cycle provided to the handpiece electrical system from the power source and/or modify the aspiration flow rate. In addition, a separate input enables manual control of pulse amplitude. The control system provides a pulsed electrical power of less than 20 millisecond pulse duration.06-30-2011
20130023817COATING FORMULATIONS FOR SCORING OR CUTTING BALLOON CATHETERS - The present invention is related to scoring or cutting balloon catheters carrying at least on a portion of their surface at least one drug or drug preparation and at least one lipophilic antioxidant at a ratio of 3-100% by weight of the at least one lipophilic antioxidant in relation to 100% by weight of the drug, wherein a combination of the at least one drug being a limus drug and the at least one lipophilic antioxidant being butylated hydroxytoluene is excluded.01-24-2013
20080243049Biodegradable Triblock Copolymers for Use in Acoustically Mediated Intracellular Drug Delivery in vivo - Targeted therapeutic delivery systems comprising specially designed nanocarriers for intracellular therapeutic delivery, mediated by acoustic energy, for use either in vivo or in vitro, are described. Nanocarriers comprised of substantially biodegradable triblock copolymers, and mixtures thereof, are used to treat a variety of diseases in humans and other species, such as cancer, opthalmological, pulmonary, urinary or other pathologies. Methods for preparing the targeted therapeutic delivery systems are also embodied, which comprise processing a solution comprised of biopolymers or other species and components, with or without targeting moieties, adding said biopolymers and other compounds to a solution containing one or more therapeutic agents, stabilizing or not stabilizing said nanocarriers, adding one or more contrast agents, and resulting in a targeted therapeutic delivery system. Preferred therapeutics for use with the present invention include nucleic acids, proteins, peptides, and other therapeutic macromolecules.10-02-2008
20080243048ULTRASOUND WOUND CARE METHOD - The present invention relates to a method of treating wounds by applying ultrasonic energy to a wound to inactivate, destroy, and/or remove infectious agents, and/or deliver a coupling medium to debride, cleanse, and/or sterilize the wound. The method of the present invention comprises the steps of placing the wound in front of the ultrasound emitting surface in near field, activating the ultrasound transducer, generating ultrasonic energy, emitting ultrasonic waves from ultrasound emitting surface, allowing ozone to be created in the near field, applying ozone to the wound, introducing a coupling medium to the ultrasound emitting surface of the wound device, sonicating the coupling medium, and applying the coupling medium to a wound.10-02-2008
20110264031ULTRASOUND THERAPY SYSTEM - In one embodiment of the present invention, a system for treating an occlusion within a patient's vasculature with ultrasonic energy comprises a catheter configured to be passed through the patient's vasculature such that a portion of the catheter is positioned at an intravascular treatment site. The system further comprises an ultrasound radiating member, an ultrasound signal generator configured to supply a drive signal to the ultrasound radiating member, an infusion pump configured to pump a therapeutic compound into the fluid delivery lumen so as to cause the therapeutic compound to be delivered to the treatment site and a controller configured to control the ultrasound signal generator and the infusion pump.10-27-2011
20130178789Monitoring Thermal Conditions To Vary Operation of an Ultrasonic Needle Tip of a Surgical Instrument - A method and apparatus to operate a surgical instrument in response to a thermal condition being detected that warrants curtailment of further operation. When the thermal condition is reached, command signals are generated that cause a needle of the surgical instrument to either have its vibrational speed slowed, have its vibrational movement stopped, or have it withdrawn from its relative position. The detection is of infrared radiation wavelengths and is carried out with either a thermal imaging device or a thermal recognition device. A corresponding temperature of the detected infrared radiation wavelengths is compared to a critical temperature to determine whether the thermal condition has been reached.07-11-2013
20080221505Expandable Blade Device for Stabilizing Compression Fractures - A medical device and method of using the device to reinforce and stabilize a compressed tissue is disclosed. The medical device is inserted into the tissue, typically a vertebral bone, cuts the tissue inside, and then a binding cement is injected into the pulped tissue without removing the tissue. The medical device is designed to disrupt and pulp the tissue without exerting a compressive force against the walls by using thin blades that buckle away from the core, and by rotating the blades while expanding/contracting the blades at the same time.09-11-2008
20130096488METHODS FOR USING ULTRASOUND FOR ENHANCING EFFICIENCY AND TARGETING OF INTRANASAL ADMINISTRATION OF THERAPEUTIC COMPOUNDS TO THE CENTRAL NERVOUS SYSTEM - The present invention is directed to methods for reducing systemic absorption of therapeutic compounds or agents while enhancing efficiency of delivery and targeting of intranasal administration of such compounds or agents to the central nervous system. More specifically, use of ultrasound technology in conjunction with intranasal delivery of a therapeutic compound, or pharmaceutical composition, wherein the intranasal delivery is preferably to the upper one third of a patient's nasal cavity, thereby reducing therapeutic compound or agent absorption into the blood. At the same time, the present invention results in reducing the delivery of therapeutic compounds and/or agents to the peripheral tissues, increases therapeutic delivery of the compounds and/or agents to the central nervous system generally, and increases targeting of the therapeutics and/or agents to specific target regions within the central nervous system.04-18-2013
20130096487DEVICE FOR APPLYING MEDICAL FLUID TO AN AREA AND FOR CUTTING WITHIN THE AREA - A device for applying medical fluid to an area and for cutting within the area is provided. The device includes an inlet port, a fluid flow channel, an outlet and a blade. The inlet port is configured for receiving the medical fluid into the device. The fluid flow channel is configured for the fluid to flow through the device. A first end of the fluid flow channel is connected to the inlet port. An outlet is configured for the fluid to come out of the device. The outlet is positioned at a second end of the fluid flow channel. The blade is configured for cutting within the area.04-18-2013
20130102956HOLLOW NEEDLE - The present invention is a hollow needle for attachment to a syringe, through which a liquid can be delivered to the stratum granulosum and/or beneath the epidermis, preferably to an area consisting from the stratum granulosum (included) to reticular dermis (included) and more preferably beneath the papillary dermis during a cosmetic procedure, the needle comprising a distal tip and including a lateral aperture adjacent to the distal tip, wherein the liquid exits the needle via the lateral aperture, and wherein the needle is flexible. Apparatus comprising a needle of the invention and a syringe, and a method of use thereof, is also provided.04-25-2013
20130123680FLUID MANAGEMENT SYSTEM FOR USE IN A MEDICAL PROCEDURE - An apparatus and method for controlling fluid flow provided by an apparatus to a patient's eye during a surgical procedure. The method includes automatically adjusting an irrigation fluid source to a predetermined height during the surgical procedure using the apparatus, receiving a request either that the irrigation fluid source be moved to a different height from the predetermined height or that a manual adjustment mode be entered, and ceasing automatic adjusting and requiring manual adjustment of the height of the irrigation fluid source until the surgical procedure is completed or an indication received to resume automatic height adjustment of the irrigation fluid source. As an alternative, fluid flow rate or intraocular pressure may be maintained, and the design may include making adjustments to default values in other modes based on the adjustment made.05-16-2013
20090149801METHOD OF INDUCING TRANSVERSE MOTION IN LANGEVIN TYPE TRANSDUCERS USING SPLIT ELECTRODING OF CERAMIC ELEMENTS - A Langevin transducer horn uses split electroding or selective electroding of transducer elements and phase relationships of the voltages applied thereto to determine the relative longitudinal and flexural/transverse motion induced in the tip of the horn.06-11-2009
20100280434AUTOMATICALLY PULSING DIFFERENT ASPIRATION LEVELS TO AN OCULAR PROBE - Methods and systems for automatically pulsing different aspiration levels to an ocular probe are disclosed. The probe may be a phacoemulsification probe. A first aspiration level, supplied by a first pump, may be applied to the probe simultaneously with ultrasonic energy. A second aspiration level, supplied by a second pump, may be automatically switched from the first aspiration level, and applied to the probe in a pulsed manner.11-04-2010
20080208108TREATMENT APPARATUS FOR OPERATION - A treatment apparatus for operation is configured to operate in a plurality of output modes. A hand piece is provided with a probe configured to supply a high-frequency current, and an ultrasonic transducer which is connected to the probe and activates ultrasonically the probe. A high frequency driving circuit supplies a high-frequency current to the probe. An ultrasonic transducer driving circuit drives the ultrasonic transducer. An operation switch selects a first output mode and a second output mode. A controller controls a high-frequency output from the high frequency driving circuit and an ultrasonic output from the ultrasonic transducer driving circuit, to operate the treatment apparatus for operation in an output mode selected by the operation switch.08-28-2008
20080200863DEVICES AND METHODS FOR SELECTIVELY LYSING CELLS - A system comprising: a container containing a measured amount of a solution including at least one of a vasoconstrictor, a surfactant, and an anesthetic, the solution comprising a liquid and at least one of a gas and a fluid; a needle array in fluid connection with the container, the needle array including at least one needle.08-21-2008
20080200862Method To Administer Stem Cells In Combination With One Or More Acoustically Active Materials And Ultrasound Energy - The invention comprises a method to administer stem cells to a patient in need thereof. The method provides acoustically active material, stem cells, and an ultrasound energy emitting device. The method administers the acoustically active material to the patient, administers the stem cells to the patient, and administers ultrasound energy to the patient using the ultrasound emitting device.08-21-2008
20100286593BALLOON CATHETER WITH CUTTING FEATURES AND METHODS FOR USE - Apparatus and methods are provided for treating a lesion within a body lumen using a catheter including a balloon on its distal end that includes a plurality of raised structures that extend outwardly from the balloon membrane. In one embodiment, the raised structures are provided in pairs that are spaced apart from one another about the circumference of the balloon, and each pair includes two raised structures that are spaced relatively closely together compared to the distance the two raised structures are spaced apart from adjacent pairs. Optionally, the membrane between the two raised structures of each pair may be relatively thinner than the membrane between spaced apart pairs such that the distance between the raised structures in each pair increases as the balloon is expanded within a lesion.11-11-2010
20120283625METHOD FOR TREATMENT OF ETHMOIDS - A method of treating diseased ethmoid sinuses in a patient with a therapeutic agent includes providing an injection device comprising an elongate member having a proximal end, a distal tip or end, and a lumen extending between the distal tip and the proximal end, the proximal end being operatively coupled to a source of the therapeutic agent. The distal tip of the injection device is inserted at least partially within an interior portion of an ethmoid air cell. The therapeutic agent is then injected into the interior portion of the ethmoid air cell using the injection device, the therapeutic agent being delivered via the lumen in the elongate member.11-08-2012
20120283624Drug Eluting Device and Method of Use Thereof - One aspect provides a balloon catheter including a cutting element having a reservoir. In one embodiment, the reservoir includes a bioactive. Another aspect provides a method for using the balloon catheter for treating a patient by breaking hardened plague on the vessel wall and dilating the vessel. In one embodiment, the bioactive is delivered to the vessel wall.11-08-2012
20110313346CATHETER FOR ASPIRATING, FRAGMENTING AND REMOVING EXTRACTABLE MATERIAL FROM BLOOD VESSELS - The invention relates to a catheter for aspirating, fragmenting and removing extractable material from hollow bodies, in particular thrombi and emboli from blood vessels, with a working head, which is arranged at the distal end of the catheter, is axially displaceable along a guide wire, independently thereof, and comprises at least one lateral opening. The catheter comprises a flexible feed screw which has a distal end and a proximal end and which can be rotated at a speed of rotation by means of a rotary drive of a drive unit remote from the working head. A flexible tube which surrounds the feed screw and is connected to the working head removes the material or the detached thrombi and emboli fragments. The feed screw is designed as a shearing cutting tool which cooperates with the opening in the working head in order to size-reduce and remove the materials or aspirated and/or detached thrombi and emboli which penetrate between the peripheral edges of the feed screw and edges of the openings. A thrust bearing is arranged between the distal end of the feed screw and the working head so as to axially support the feed screw, and is designed as a disc which can be rotated by the feed screw during operation.12-22-2011
20110313345ULTRASONIC DEVICE FOR HARVESTING ADIPOSE TISSUE - Described are embodiments of methods and devices for removing adipose tissue from a surgical site or location in a patient's body. The embodiments include a device that is used for infiltration, ultrasound, and aspiration of the surgical site. The device includes a cannula which serves to provide infiltration, conduct ultrasonic energy from an ultrasound generating device, and also provide a conduit for aspiration to a fluid system used for infiltration and collection of fluids. Embodiments provide for a fixed amount of infiltration fluid to be injected into the surgical site in specific ratio with the amount of lipoaspirate to be removed. The fixed amount of ultrasonic energy, both in amplitude and time, is delivered to the surgical site commensurate with the amount of infiltration and aspiration. The device also includes, in embodiments, a guide that limits the depth to which the cannula can be inserted into a patient.12-22-2011
20110313344Method for treating refractive errors and vision disorders of an eye - A method for treating refractive errors and vision disorders of an eye includes fixing a suction ring to an eye, applanating a cornea of the eye, guiding a blade into the cornea with a guiding mechanism, creating a pocket inside the cornea by guiding the blade inside the cornea, removing the blade from the cornea and removing the suction ring from the eye.12-22-2011
20110313343Phacoemulsification Fluidics System Having a Single Pump Head - A phacoemulsification fluidics system for irrigating and aspirating a surgical site includes a sterile solution reservoir, an irrigation path configured to extend from the sterile solution reservoir to the surgical site, and an aspiration path configured to extend from the surgical site. The system also includes a single flow control pump head associated with both the irrigation path and the aspiration path. The flow control pump head is arranged within the system to simultaneously pressurize the irrigation path in a manner that drives the irrigation fluid to the surgical site and pressurize the aspiration path in a manner that vacuums waste fluid from the surgical site.12-22-2011
20120029422SYSTEM AND METHOD FOR PAIN REDUCTION DURING SKIN PUNCTURE AND BREAKABLE TIP THEREFOR - An instrument, article and method are provided for minimizing pain during administration by injection of a liquid, such as, an anesthetic. The instrument has a forward end. A rod or lightpipe mounted freely for vibration projects out of the forward end. The article, a single use tip, is composed of a tip sleeve removably mounted on the forward end of the instrument and a tip member removably mounted on the projecting rod or lightpipe to vibrate a preselected injection site on a human or animal. The tip sleeve and tip member are covered by an elastic overmold that enables the tip member to vibrate freely with respect to the tip sleeve and light from the lightpipe to illuminate the injection site. The overmold of the single use tip is torn during removal of the single use tip from the instrument.02-02-2012
20120029421MEDICAL DELIVERY SYSTEMS AND APPARATUS - A catheter proximal section is preferably formed from a relatively soft part and a relatively rigid part, and includes a proximal terminal end that defines a perimeter of an opening into a lumen of the catheter. The proximal section may further include a feature for interlocking engagement with an accessory tool. An inner surface of each of the relatively soft and rigid parts may be located opposite one another, on either side of the catheter lumen. The relatively soft and rigid parts may be included in a sealing assembly that further includes an attachment feature for removable connection of the assembly to the proximal section catheter.02-02-2012
20120296264Method of Controlling a Surgical System Based on a Load on the Cutting Tip of a Handpiece - A surgical system that is able to sense the onset of an occlusion or other surgical event as well as the instant an occlusion breaks. To help avoid overheating of the tip, the system determines an approximate temperature of the eye using an irrigation flow rate and reduces the power to the handpiece automatically if an overheating situation is predicted. Alternatively or in addition, the system monitors the power drawn by the handpiece, which is indicative of the cutting load on the tip, and automatically adjusts the power or stroke of the tip to compensate for increased loads on the tip.11-22-2012
20090259168Bandage - Sticky bandage (SB) for a topical treatment providing for massaging while applying cosmetic agents or drugs to a skin of a user is provided. The SB consists of a vibrating member and a layered SB base. The SB is electrically powered either by an internal battery or from an external source. The proximal layer (that is closer to the skin) of the SB base includes the active substances and is optionally replaceable. The vibrating member consists of piezoelectric ceramics, arrays of electromagnets, or miniature electric motor and programmable activation logic. Optionally the battery or the connector providing for electrical powering and an activation switch are installed in a separate housing that is electrically connected to the SB. An electrical safety circuit is provided to prevent an accidental activation of the vibrating member.10-15-2009
20130204179Methods and Systems for Delivering Substances Into Luminal Walls - Angioplasty and other dilatation devices are provided with scoring elements which incorporate a drug to be delivered to a body lumen, typically a blood vessel. The non-cutting scoring elements have drugs and other active substances coated over a portion thereof or incorporated within internal structure of the element so that the drug is released into the luminal wall closely associated diseased regions of the body lumen as the non-cutting scoring structure is radially expanded into the wall.08-08-2013
20120095389ULTRASOUND CATHETER FOR PROVIDING A THERAPEUTIC EFFECT TO A VESSEL OF A BODY - The invention relates to a catheter system. The system comprises a catheter body having a chamber containing a low acoustic impedance medium. The catheter body includes an elongated body with an external surface and an ultrasound transducer having an external side between a first end and a second end. The ultrasound transducer is positioned over the external surface of the elongated body such that the first end is adjacent to the chamber.04-19-2012
20130211315Near Quadrant Glaucoma Treatment Method - A method of treating glaucoma is described. The method includes creating an incision at or near the limbus of an eye and treating glaucoma by inserting a treatment probe through the incision to act on an eye structure adjacent to or near the incision.08-15-2013
20130211317Device, A Kit And A Method For Treatment Of Disorders In The Heart Rhythm Regulation System - A tissue lesion creating device is structured and arranged to be inserted through the vascular system into a body vessel adjacent the heart and to be subsequently subjected to a change of shape in order to penetrate into the heart tissue. The tissue lesion creating device may thus be used for treating disorders to the heart rhythm regulation system. A kit of devices provides a plurality of devices for creating a lesion pattern for treating such disorders.08-15-2013

Patent applications in class With means for cutting, scarifying, or vibrating (e.g., ultrasonic, etc.) tissue