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Ultrasonic

Subclass of:

601 - Surgery: kinesitherapy

601001000 - KINESITHERAPY

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Class / Patent application numberDescriptionNumber of patent applications / Date published
601003000 Hyperthermia 95
Entries
DocumentTitleDate
20100063423ULTRASONIC BATH TO INCREASE TISSUE PERFUSION - The present invention describes a method of using an ultrasonic bath to enhance tissue perfusion, enhance the development of collateral blood vessels and/or enhance collateral circulation in an extremity in need thereof. Also described is an ultrasonic bath adapted to hold media and to permit the immersion of an extremity and comprising one or more ultrasonic transducers to generate and transmit ultrasonic energy to the extremity or the inventive method03-11-2010
20130072825APPARATUS AND METHODS FOR THE DESTRUCTION OF ADIPOSE TISSUE - Methods and apparatus are described for modifying unwanted tissue for cosmetic reasons. The methods provide a non-invasive manner to perform body contouring by destroying adipose tissue while simultaneously causing collagen contraction in a single procedure so that as destroyed tissue is removed from a treatment volume, the volume shrinks gradually to maintain the skin tone of the treatment area. The procedure may involve multiple treatments to the same treatment area or location.03-21-2013
20110201974TREATMENT OF VASCULAR OCCLUSIONS USING ULTRASONIC ENERGY AND MICROBUBBLES - In one embodiment of the present invention, a method of treating a vascular occlusion located at a treatment site within a patient's vasculature comprises positioning an ultrasound catheter at the treatment site. The method further comprises delivering a microbubble-therapeutic compound from the ultrasound catheter to the vascular occlusion during a first treatment phase. The method further comprising 08-18-2011
20130030329APPARATUS AND METHODS FOR FRICTION REDUCTION - An apparatus, system and methods thereof for generating an acoustic lubrication effect along a surface of an in-dwelling medical device that is in contact with a vital tissue in a subject are provided. The vibrations comprise: Hz range cylindrical surface vibrations; or kHz range surface acoustic wave (SAW) vibrations; or a combination thereof. The vibrations create an acoustic lubrication effect that may reduce pain or discomfort in a subject when the apparatus is used with an indwelling medical device. The vibrations may enhance tactile sensation when the medical device is a shoe pad.01-31-2013
20130030328Ultrasonic Dissection System - An ultrasonic surgical system is provided. The ultrasonic surgical system includes an ultrasonic instrument that is configured to ultrasonically treat tissue. An ultrasonic generator configured to provide ultrasonic energy to the ultrasonic instrument provides an indication to a user that a specific outcome has been achieved. The indication is output via a device selected from an audio activation end-tone device, a visual activation end-tone device or a tactile activation end-tone device. The ultrasonic generator includes an end-tone outcome indicator module that includes memory having one or more data look up tables that is accessible by a microprocessor associated with the ultrasonic generator.01-31-2013
20090069725ENHANCED ULTRASOUND PLATFORM - An enhanced ultrasound housing and enhanced ultrasound platform facilitates a technician-friendly layout by providing a beneficial ergonomic layout. Control switches may also be configured to provide convenient implementation of ultrasound techniques. Further, an enhanced ultrasound housing and enhanced ultrasound platform provides physical protection to the device. Physical protection may come in the form of an exoskeletal member, or from a covering which inhibits liquid penetration.03-12-2009
20100010394Noninvasively low-frequency ultrasonic apparatus for the brain therapy - Ultrasonic energy has been proven that at suitable frequency range (670-kHz to 2-MHz), ultrasound can be focused to a specific target, and the concentrated energy has sufficient high acoustic pressure so that capable of inducing localized blood-brain barrier (BBB) disruption, which has an important implication on noninvasively delivering drug into brain.01-14-2010
20100094179Optimized Diffraction Zone for Ultrasound Therapy - A system and method for ultrasound therapy may include a transducer configured to deliver an ultrasound wave to tissue. Means for manipulating the diffraction pattern alter the transition point between the near field and far field.04-15-2010
20110196267ULTRASOUND NEUROMODULATION OF THE OCCIPUT - Disclosed are methods and systems for non-invasive neuromodulation of the occipital nerves using ultrasound transducers to treat migraine and cluster headaches in their multiple variations as well other pain and tension conditions. Treatment may be unilateral or bilateral.08-11-2011
20110196266HANDPIECE FOR ULTRASONIC MEDICAL DEVICES - Described are embodiments including methods and devices for venting a handpiece of a medical device. These embodiments provide a vent for the handpiece. A porous membrane is positioned over an opening of the vent to allow gas, including steam, to enter and escape from the handpiece and prevent liquids from entering the handpiece. Other embodiments include methods and devices for holding an ultrasonic driver assembly within a handpiece and preventing the ultrasonic driver assembly from rotating within the handpiece. These embodiments include positioning the ultrasonic driver assembly such that the ultrasonic driver assembly is held in place at a node of the ultrasonic driver assembly and an anti-rotation mechanism is also located at the node.08-11-2011
20110196265FREQUENCY MODULATED ULTRASONIC THERAPEUTIC APPARATUS FOR BONE FRACTURE AND METHOD FOR GENERATING FREQUENCY MODULATED ULTRASONIC WAVE - A frequency modulated ultrasonic therapeutic apparatus for bone fractures and a method for generating frequency modulated ultrasonic waves are revealed. The frequency modulated ultrasonic therapeutic apparatus includes a control interface, a control unit, a waveform generator circuit and a transducer. The control interface is used to set a plurality of parameters. The control unit coupled to the control interface generates a control signal according to those parameters. The waveform generator circuit is coupled to the control unit and is generating a waveform signal according to the control signal. The transducer converts the waveform signal and produces an ultrasonic wave. The present invention provides different parameters for modulating a frequency of ultrasonic waves. Ultrasonic waves with different frequencies are used to treat bone fractures during the bone healing process of living animals. Thus the fracture healing is speeded up and the recovery time is reduced.08-11-2011
20130211292ULTRASOUND EMISSION ELEMENT - There is provided in accordance with an exemplary embodiment of the invention an ultrasound catheter for intrabody medical therapy comprising; an element adapted to emit ultrasound energy; at least two electrodes configured to apply a voltage across at least some volume of the element; and a gas bubble containment area adapted to retain the gas bubble when in blood.08-15-2013
20130085419Transducer/Waveguide Engagement Mechanisms for Ultrasonic Surgical Instruments - An ultrasonic surgical instrument includes a transducer assembly having a distal engagement member and configured to supply ultrasonic energy. A waveguide defines a longitudinal axis and has a proximal engagement member configured to threadingly engage the distal engagement member. The waveguide is configured to transmit the ultrasonic energy therealong to a distal end thereof for treating tissue. A torque member is coupled to the transducer assembly and is disposed about the longitudinal axis. The torque member is selectively rotatable about the longitudinal axis and relative to the waveguide to threadingly engage the transducer assembly and the waveguide to one another. The torque member includes a plurality of fingers pivotably coupled thereto and movable between a closed position and an open position. In the open position, each finger extends substantially perpendicularly from the longitudinal axis to define a moment arm that facilitates the engagement of the transducer assembly and the waveguide.04-04-2013
20100076352APPARATUS USING FOCUSED ULTRASOUND WAVE BY CONTROLLING ELECTRONIC SIGNALS AND USING METHOD THEREOF - The present invention relates to an extracorporeal High Intensity Focused Ultrasound (HIFU) necrosis apparatus through the control of an electronic signal, including oscillation elements for generating ultrasonic beams, an ultrasonic oscillator array having the oscillation elements fixed on a plane and oriented toward a life, delay circuits respectively connected to the oscillation elements for delaying ultrasonic oscillation by a delay time, and control means for controlling the delay time so that the ultrasonic beams are focused, and a method of employing the same. According to the present invention, waved surfaces with a variety of directions and curvatures can be formed using several oscillation elements and several delay circuits disposed on a plane, and a focus can be formed at any desired place. Accordingly, there are advantages in that installation is convenient, and a tissue, such as tumor, which is a target tissue, can be necrotized without damage to normal tissues necrosis. Further, there is no damage to normal tissues other than a target tissue. Accordingly, there are advantages in that a recovery speed of a patient can quicken, a symptom after recovery can be mitigated, and so on.03-25-2010
20100076349Spider Vein Treatment Apparatus - A medical ultrasound apparatus and associated methods of use is disclosed enabling a relatively non-invasive or minimally invasive method to treat skin or tissue. The apparatus is constructed from an ultrasound tip mechanically coupled to a shaft. The shaft is mechanical coupled to an ultrasound transducer driven by an ultrasound generator. The ultrasound tip possesses at least one radial surface, a cavity, or some other form of a hollowed out area, within at least one of the radial surfaces, and a non-metallic sheath covering portions of the tip so that only the sheath and not the tip would normally contact the patient's skin. The disclosed method of treating spider, reticular or small varicose veins with the apparatus can be practiced by contacting the sheath with the patient's epidermal skin layers and delivering ultrasonic energy released from the various surfaces of the vibrating tip to the skin and/or tissue through direct contact and/or with a coupling fluid focused from a cavity.03-25-2010
20100076350Methods for Treatment of Spider Veins - A medical ultrasound apparatus and associated methods of use is disclosed enabling a relatively non-invasive or minimally invasive method to treat skin or tissue. The apparatus is constructed from an ultrasound tip mechanically coupled to a shaft. The shaft is mechanical coupled to an ultrasound transducer driven by an ultrasound generator. The ultrasound tip possesses at least one radial surface, a cavity, or some other form of a hollowed out area, within at least one of the radial surfaces, and a non-metallic sheath covering portions of the tip so that only the sheath and not the tip would normally contact the patient's skin. The disclosed method of treating spider, reticular or small varicose veins with the apparatus can be practiced by contacting the sheath with the patient's epidermal skin layers and delivering ultrasonic energy released from the various surfaces of the vibrating tip to the skin and/or tissue through direct contact and/or with a coupling fluid focused from a cavity.03-25-2010
20120245494METHODS FOR TREATMENT USING ULTRASONIC ENERGY - In some examples, nerves surrounding arteries or leading to organs are targeted with energy sources to correct or modulate physiologic processes. In some examples, different types of energy sources are utilized singly or combined with one another. In some examples, bioactive agents or devices activated by the energy sources are delivered to the region of interest and the energy is enhanced by such agents or the agents are enhanced by the energy sources.09-27-2012
20120245493ULTRASOUND NEUROMODULATION TREATMENT OF ADDICTION - Disclosed are methods and systems and methods for non-invasive neuromodulation using ultrasound to treat addiction. The neuromodulation can produce acute or long-term effects. The latter occur through Long-Term Depression (LTD) and Long-Term Potentiation (LTP) via training. Included is control of direction of the energy emission, intensity, frequency, pulse duration, and phase/intensity relationships to targeting and accomplishing up regulation and/or down regulation.09-27-2012
20130079682ULTRASOUND-NEUROMODULATION TECHNIQUES FOR CONTROL OF PERMEABILITY OF THE BLOOD-BRAIN BARRIER - Disclosed are methods and systems and methods employing non-invasive ultrasound-neuromodulation techniques to control the permeability of the blood-brain barrier. For example, such an alteration can permit increased penetration of a medication to increase its therapeutic effect. The neuromodulation can produce acute or long-term effects. The latter occur through Long-Term Depression (LTD) and Long-Term Potentiation (LTP) via training. Included is control of direction of the energy emission, intensity, frequency (carrier and/or neuromodulation frequency), pulse duration, firing pattern, and phase/intensity relationships for beam steering and focusing on targets and accomplishing up-regulation and/or down-regulation.03-28-2013
20130079681FOCUSED ULTRASOUND THERAPY APPARATUS AND FOCAL POINT CONTROLLING METHOD THEREOF - A focal point controlling method and a focused ultrasound therapy apparatus may be used in the treatment and removal of a lesion in a noninvasive surgical procedure by focusing ultrasonic waves. A focal point may be controlled by acquiring tissue characteristic information including physical characteristic values affecting propagation of an ultrasonic wave from a pre-diagnostic image that is a medical image obtained by capturing tissues on a path through which the ultrasonic wave propagates from a position from which the ultrasonic wave is generated to a target position on which a focal point is desired to be formed. The position at which the focal point is formed may be controlled by using the acquired tissue characteristic information.03-28-2013
20100036291OPTIMIZATION AND FEEDBACK CONTROL OF HIFU POWER DEPOSITION THROUGH THE FREQUENCY ANALYSIS OF BACKSCATTERED HIFU SIGNALS - A system and method for dynamically adjusting the energy of HIFU signals delivered to a patient, and/or to aid in visualizing the likely degree and location of HIFU effects on patient tissue. The system transmits a HIFU signal into a patient and receives echoes therefrom. The echo signals are analyzed to determine the energy of the signals in a first range, such as at one or more harmonics and/or sub-harmonics of the fundamental frequency of the HIFU signal, and energy of the echo signals in a second range such as at the fundamental frequency of the HIFU signal. Based on the comparison, the energy and/or focus of the HIFU signals delivered to the patient is adjusted. An image of the compared echo signal powers in two or more frequency ranges may also be displayed for a user or used to adjust the focus point of the HIFU signals.02-11-2010
20130041292Customizable Haptic Assisted Robot Procedure System with Catalog of Specialized Diagnostic Tips - In accordance with the present disclosure, a system and method for using a remote control to control an electrosurgical instrument, where the remote controlled (RC) electrosurgical instrument has a universal coupling mechanism to allow switching between an interchangeable catalog of diagnostic tools. A controller within the base of the RC electrosurgical instrument identifies the type of disposable tip attached to the base. The controller, then, activates necessary features for use with the identified tip and deactivates any unnecessary features. A surgeon uses a remote with at least one momementum sensor to control the RC electrosurgical instrument 02-14-2013
20130041293LESION GENERATION THROUGH BONE USING HISTOTRIPSY THERAPY WITHOUT ABERRATION CORRECTION - A medical imaging and therapy device is provided that may include any of a number of features. The device may include a Histotripsy transducer, a generator and controller configured to deliver Histotripsy energy from the transducer to target tissue, and an imaging system. In some embodiments, a method of treating tissue with Histotripsy energy comprises positioning a focus of a histotripsy transducer on a target tissue, delivering histotripsy energy from the histotripsy transducer through a bone aberrator, forming a histotripsy bubble cloud on the focus, and preventing the formation of secondary histotripsy bubble clouds without implementing an aberration correction algorithm.02-14-2013
20100100014Non-Thermal Acoustic Tissue Modification - A methodology and system for modifying tissue including an acoustic transducer assembly (04-22-2010
20100042019APPARATUS AND METHODS FOR THE DESTRUCTION OF ADIPOSE TISSUE - Methods and apparatus are described for modifying unwanted tissue for cosmetic reasons. The methods provide a non-invasive manner to perform body contouring by destroying adipose tissue while simultaneously causing collagen contraction in a single procedure so that as destroyed tissue is removed from a treatment volume, the volume shrinks gradually to maintain the skin tone of the treatment area. The procedure may involve multiple treatments to the same treatment area or location.02-18-2010
20100042018DEVICE FOR TREATING CELLULITE AND FATTY MASSES02-18-2010
20090156969Method and equipment to induce osteogenesis in a bone region of a patient - Apparatus and method to induce osteogenesis in a bone region of a patient, by which at least one beam of ultrasounds is generated, focused and directed toward a bone region of a patient, such that the beam focus is matched with a specific point of the bone region. The ultrasound beam hits the bone region with an intensity and for a duration such to cause a hematoma and/or local inflammation and/or a series of micro-fractures in the target bone region, thereby activating a mechanism of osteogenesis.06-18-2009
20090005712SYSTEM AND METHOD FOR CONTROLLING A TRANSVERSE PHACOEMULSIFICATION SYSTEM WITH A FOOTPEDAL - A method and system for controlling an ultrasonically driven handpiece employable in an ocular surgical procedure is provided. The method includes operating the ultrasonically driven handpiece in a first tip displacement mode, such as a longitudinal mode according to a first set of operational parameters, and enabling a user to alter the ultrasonically driven handpiece to employ a second tip displacement mode, such as a transversal or torsional mode, using a second set of operational parameters. Enabling the user to alter performance of the handpiece comprises the user being enabled to dynamically select operational parameters for the first tip displacement mode relative to the second tip displacement mode by using, for example, a switching apparatus such as a footpedal.01-01-2009
20090131838Method and system for the enhancement and monitoring of the healing process of bones - The present invention relates to a method and a system to therapeutically treat bone fractures, nonunions, deformities and also to monitor their healing process using ultrasound waves.05-21-2009
20120109021RENAL DENERVATION CATHETER EMPLOYING ACOUSTIC WAVE GENERATOR ARRANGEMENT - A transducer supported by a positioning arrangement is placed within a renal artery at a desired location that is a predetermined distance from a reflector equal to an odd number of quarter wavelengths of acoustic energy emitted by the transducer. The positioning arrangement is actuated to transition from a low-profile introduction configuration to a deployed configuration within the renal artery thereby stabilizing the transducer at a desired location. Acoustic energy is emitted by the transducer so that it propagates axially along an outer surface of the target vessel to impinge the reflector, which can be biological or artificial. The emitted energy builds up to resonance at a point of reflection defined by a location of the reflector, and the amount of energy build up is sufficient to ablate perivascular renal nerves in the vicinity of the reflector.05-03-2012
20100094177SYSTEMS AND METHODS FOR SYNCHRONIZING ULTRASOUND TREATMENT OF THRYOID AND PARATHYROID WITH MOVEMENTS OF PATIENTS - A treatment device and methods for HIFU treatment of thyroid and parathyroid disorders are provided. The treatment device comprises the first sensor for detecting swallowing motion and the second sensor for tracking the motion of the thyroid and parathyroid tissue with ultrasound imaging. Thus, the treatment device allows for safe and non-invasive use of HIFU on thyroid and parathyroid tissue of patients by synchronizing HIFU pulse delivery with patient swallowing and/or directing the applicator of HIFU energy to follow the appropriate tissue when the patient moves.04-15-2010
20120184879MEDICAL DEVICE WITH TEMPERATURE SENSOR - A medical device includes at least one ultrasound transducer, at least one temperature sensor, at least one driver circuit, and at least one processing device. The temperature sensor is configured to detect a temperature at or adjacent a surface of the ultrasound transducer that emits ultrasound during operation of the ultrasound transducer. The driver circuit is coupled to the ultrasound transducer. The processing device is configured to (i) determine whether the temperature detected by the temperature sensor meets a defined condition, (ii) control the driver circuit such that the ultrasound transducer produces ultrasound with therapeutic properties if the determination indicates that the temperature meets the defined condition and (iii) control the driver circuit such that the ultrasound transducer does not produce ultrasound if the determination indicates that the temperature does not meet the defined condition.07-19-2012
20100010395ULTRASOUND EMITTING SYSTEM AND ULTRASOUND TREATMENT MACHINE COMPRISING SAID SYSTEM - An ultrasound emission system comprising a substantially cylindrical body and, inside said body: a piezoelectric assembly for producing ultrasound along the axial direction of said body, a sonotrode assembly, a prestress ring, and further comprising electrical power supply and control means; said piezoelectric assembly being constituted by a stack of layers of piezoelectric material, each layer being provided with excitation electrodes and presenting thickness lying in the range 20 μm to 100 μm. The system, generally fitted with a cannula enabling the ultrasound treatment to be applied to a determined area, can itself be incorporated in such a manner as to make an ultrasound treatment machine serving in particular to perform phacoemulsification.01-14-2010
20130046208ULTRASOUND DEVICE FOR TREATMENT OF INTERVERTEBRAL DISC TISSUE - An ultrasound device and method for the treatment of intervertebral disc tissue for remediation of back pain. An applicator comprises a catheter and/or needle with a distal tip including one or more ultrasound transducer crystals. The crystals produce high-powered ultrasound energy that is transmitted and absorbed in the disc tissue. The resulting temperature elevation of the disc tissue shrinks the collagen fibers in the surrounding tissue, and/or destroying small nerves that may have invaded and innervated the surrounding degenerated tissue, and can provide increased structural integrity and disc support for the fragmented nucleus pulposus to relieve pressure on the spinal nerves.02-21-2013
20130046207APPARATUSES AND SYSTEMS FOR GENERATING HIGH-FREQUENCY SHOCKWAVES, AND METHODS OF USE - Apparatuses and methods for generating therapeutic shock waves. Some embodiments comprise: an acoustic-wave generator configured to emit acoustic waves having at least one frequency between 1 MHz and 1000 MHz; a shock wave housing coupled to the acoustic-wave generator; and a shock wave medium disposed in the shock wave housing; where the apparatus is configured such that if the acoustic-wave generator emits acoustic waves then at least some portion of the acoustic waves will travel through the shock wave medium and form one or more shock waves.02-21-2013
20090254007PRESSURE PULSE/SHOCK WAVE THERAPY METHODS AND AN APPARATUS FOR CONDUCTING THE THERAPEUTIC METHODS - The method of stimulating a substance is disclosed. The method has the steps of activating an acoustic shock wave generator or source to emit acoustic shock waves; and subjecting the substance to the acoustic shock waves stimulating said substance wherein the substance is positioned within a path of the emitted shock waves and away from a geometric focal volume or point of the emitted shock waves. In one embodiment the emitted shock waves are divergent or near planar. In another embodiment the emitted shock waves are convergent having a geometric focal volume of point at a distance of at least X from the source, the method further comprising positioning the substance at a distance less than the distance X from the source. The substance is a tissue having cells. The tissue can be an organ of a mammal. The mammal may be a human or an animal. The organ may be a heart, a brain, skin, a liver or a kidney or any other organ. The tissue may be muscle, cartilage, tendon, bone, teeth or gums. The tissue may be a part of the vascular system, a part of the nervous system, a part of the urinary or reproductive system, a part of the lymph node or pituitary systems, a part of the ocular system or a part of a skeletal system.10-08-2009
20130090577ULTRASONIC SURGICAL INSTRUMENT WITH MODULAR END EFFECTOR - A surgical instrument having a transmission assembly, a transducer, and a handle assembly is configured for coupling the transmission assembly to the handle assembly using a locking mechanism. The locking mechanism is operable to restrict the rotational movement of an actuator coupling member and the transducer relative to the handle assembly. The locking mechanism may also be operable to lock a trigger of the handle assembly in a first position. An inner tubular actuating member of the transmission assembly may be threadably attachable to the actuator coupling member or the actuator coupling member may include a latching mechanism to couple to a flared portion of the inner tubular actuating member. A waveguide of the transmission assembly may also be threadably attachable to the transducer. In one alternative, the trigger may be configured to operate the locking mechanism, either in the first position or when pivoted distally to a third position.04-11-2013
20130090576SURGICAL INSTRUMENT WITH ULTRASONIC WAVEGUIDE DEFINING A FLUID LUMEN - A surgical system comprises an ultrasonic surgical instrument and a conduit. The conduit may be coupled with a vacuum source and/or a fluid source. The instrument comprises an ultrasonic transducer, a waveguide, and an end effector. The waveguide extends fully through the transducer, such that a distal end of the waveguide is distal to the distal end of the transducer and such that a proximal end of the waveguide is proximal to the proximal end of the transducer. The waveguide is operable to transmit ultrasonic vibrations from the transducer to the end effector. The waveguide defines a lumen in fluid communication with the conduit. The lumen is also in fluid communication with the end effector. The end effector may thus be used to deliver one or more of ultrasonic energy, suction, and/or fluid to a surgical site, in any suitable sequence or simultaneously.04-11-2013
20130090579Pulsed Cavitational Therapeutic Ultrasound With Dithering - Cavitation memory effects occur when remnants of cavitation bubbles (nuclei) persist in the host medium and act as seeds for subsequent events. In pulsed cavitational ultrasound therapy, or histotripsy, this effect may cause cavitation to repeatedly occur at these seeded locations within a target volume, producing inhomogeneous tissue fractionation or requiring an excess number of pulses to completely homogenize the target volume. Cavitation memory can be removed with a dithering technique. The spatial-temporal memory effect of micro-bubbles can be defeated by (1) passive temporal dithering, (2) active dithering, or (3) use of therapy pulses above the de novo threshold.04-11-2013
20130090578DEVICE AND METHODS FOR RENAL NERVE MODULATION - Systems for nerve modulation are disclosed. An example system may include a first elongate element having a distal end and a proximal end and having at least one transducer disposed adjacent the distal end. The transducer may be an ultrasound transducer. Activation of the transducer may radiate acoustic energy from in two directions simultaneously.04-11-2013
20130090575SURGICAL INSTRUMENT WITH TRANSDUCER CARRIER ASSEMBLY - A surgical instrument includes an ultrasonic transducer, a body, and a transducer carrier assembly. The ultrasonic transducer is operable to deliver energy through the surgical instrument to a surgical site. The body is operable to house the ultrasonic transducer. The transducer carrier assembly is in communication with the body and the ultrasonic transducer. The transducer carrier assembly is operable to enable the translation and/or the rotation of the ultrasonic transducer within the body.04-11-2013
20090306552ULTRASONIC MEDICAL APPARATUS - The present invention solves the issue of bacterial infection by medical devices such as intracorporeal indwelling catheters. The present invention relates to an ultrasonic medical apparatus including a medical device (titanium oxide coated medical device 12-10-2009
20090306551CONTROLLING ACOUSTIC MODES IN TISSUE HEALING APPLICATIONS - A modal converter assembly [12-10-2009
20090306550Ultrasonic Endometrial Cryoablation Method - The present invention relates to an ultrasound assisted cryogenic surgical instrument, more particularly, to methods and devices utilizing ultrasound energy for treatment of the endometrium to control heavy uterine bleeding (menorrhagia) or other conditions. The device of the present invention comprises an ultrasound generator, an ultrasound transducer, a transducer tip at the distal end of the ultrasound transducer, and a radiation surface. Ultrasonic radiation is directed into the tissue being ablated. A cryogenic solution is circulated through the ultrasound tip to transfer thermal energy away from the tissue to freeze the tissue being ablated by providing a synergistic effect with the ultrasonic radiation.12-10-2009
20090306549Methods and Apparatus for Configuring an Ablation Source of a Catheter - Embodiments of the invention relate to a catheter having an ultrasound energy emitting region that is both rotatable about and slidable along the shaft of the catheter. One embodiment is directed to a catheter comprising an ultrasound transducer coupled to the shaft, and at least one actuator coupled to the handle and the ultrasound transducer that is adapted to move the ultra-sound transducer both longitudinally along the shaft and circumferentially about the shaft. Another embodiment of the invention is directed to a catheter comprising an ultrasound transducer coupled to the shaft, and at least one actuator that is adapted to move the sheath both longitudinally along the shaft and circumferentially about the shaft to orient a window of the sheath in a desired position.12-10-2009
20090093737ULTRASOUND APPARATUS WITH TREATMENT LENS - An ultrasound apparatus comprising an ultrasound transducer having a geometric focus; an acoustic lens assembly acoustically coupled to the ultrasound transducer; wherein the acoustic lens assembly includes a focal layer that serves to increase relative acoustic pressure in a treatment region proximal to the transducer's geometric focus.04-09-2009
20130072824ULTRASOUND CATHETER FOR DISRUPTING BLOOD VESSEL OBSTRUCTIONS - Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, an ultrasound catheter includes an elongate flexible catheter body with one or more lumens. An ultrasound transmission member or wire extends longitudinally through the catheter body lumen and, in many embodiments, a guide wire tube also extends through the same lumen. A distal head is fixed to or otherwise mechanically coupled with the distal end of the ultrasound transmission member or wire and is positioned adjacent the distal end of the catheter body. Although the distal end of the catheter body overlaps the distal head, the distal head is not directly affixed to the distal end of the catheter body. Thus, the distal tip may move freely, relative to the distal end of the catheter body when ultrasonic energy is applied through the ultrasound transmission member. Such a freely floating distal head enhances the efficiency of an ultrasound catheter, enabling the catheter to ablate calcific occlusions and increasing the useful life of the ultrasound transmission member and catheter.03-21-2013
20110060253ULTRASONIC CATHETER WITH AXIAL ENERGY FIELD - A catheter system for delivering ultrasonic energy to a treatment site within a body lumen comprises a tubular body. The tubular body has a proximal end, a distal end and an energy delivery section positioned between the proximal end and the distal end. The catheter further comprises an inner core configured for insertion into the tubular body. The inner core comprises a first ultrasound radiating member axially separated from a second ultrasound radiating member by an intermediate flexible joint region. The inner core further comprises an electrically conductive portion configured to allow a voltage difference to be applied to at least one of the ultrasound radiating members. The inner core further comprises a high impedance cap positioned proximal to at least one of the ultrasound radiating members.03-10-2011
20130060169MEDICAL APPARATUS - A treatment apparatus includes an ultrasonic vibration source, an ultrasonic treatment portion which is configured to treat living tissue by ultrasonic vibration transmitted from the ultrasonic vibration source, and a micrograin feeder which is configured to supply liquid containing micrograins to between the ultrasonic treatment portion and the living tissue. Whole micrograins within the micrograin-containing solution has a grain size equal to or smaller than an amplitude of the ultrasonic vibration.03-07-2013
20110015548METHODS AND APPARATUS FOR TREATMENT OF OBESITY - Method and apparatus for treating obesity by use of transesophageal delivery of energy to interrupt the function of vagal nerves.01-20-2011
20100063422ULTRASOUND THERAPY TRANSDUCER HEAD AND ULTRASOUND THERAPY SYSTEM INCORPORATING THE SAME - An ultrasound therapy transducer head comprises an ultrasound source emitting ultrasonic radiation, the ultrasound source comprising a plurality of transducer elements, integrated driving electronics coupled to the transducer elements, the electronics generating at least one output ultrasound waveform and driving at least some of the transducer elements independently based on the at least one output ultrasound waveform and temperature control structure providing cooling for the electronics.03-11-2010
20090270771SURGICAL INSTRUMENT - A surgical instrument is provided including: an ultrasonic transducer for generating ultrasonic vibration; an ultrasonic probe for transmitting the ultrasonic vibration generated by the ultrasonic transducer to a distal end portion; a grasping member capable of grasping a living tissue as an object to be treated between the grasping member and a distal end portion of the ultrasonic probe by moving between positions close to and distant from the distal end portion of the ultrasonic probe; a conductive member configured of a conductive material for supplying high-frequency current to the living tissue, the conductive member being provided to the grasping member; and a non-conductive member configured of a non-conductive material and formed in a shape for blocking a contact between the conductive member and the ultrasonic probe and exposing a part of one surface of the conductive member on the ultrasonic probe side, the non-conductive member being provided to the grasping member so as to be located between the conductive member and the ultrasonic probe, thereby allowing high-frequency current to be effectively conducted to a living tissue.10-29-2009
20090088667SURGICAL OPERATING APPARATUS - A surgical tool includes a sheath, a probe body, a distal end portion and a proximal end portion. A probe distal end portion is provided at the distal end portion of the probe body, a jaw is rotatably supported on the distal end portion of the sheath and is engaged with the probe distal end portion. A first tubular member a fits on the proximal end portion of the sheath and extends rearward. It has an elongated slit and extends in an axial direction of the sheath. A second tubular member fits in a rear end portion of the first tubular member. A tubular driving member is slidably inserted in the sheath and rotates the jaw. A coupling member including a projection body passes through the second tubular member, includes an engaging portion which is engaged in the slit of the first tubular member.04-02-2009
20130066239ULTRASOUND NEUROMODULATION OF THE BRAIN, NERVE ROOTS, AND PERIPHERAL NERVES - Disclosed are methods and systems for non-invasive ultrasound neuromodulation of superficial cortex of the brain or stimulation of nerve roots or peripheral nerves. Such stimulation is used for such purposes as determination of motor threshold, demonstrating whether connectivity to peripheral nerves or motor neurons exists and performing nerve conduction-speed studies. Neuromodulation of the brain allows treatment of conditions such as depression via stimulating superficial neural structures that have connections to deeper involved centers. Imaging is optional.03-14-2013
20130066240ULTRASOUND TRANSDUCER FOR SELECTIVELY GENERATING ULTRASOUND WAVES AND HEAT - In order to provide heating means for an ultrasonic application setup, adapted for heating a sample (03-14-2013
20130066238High-frequency operation apparatus and operation apparatus - A high-frequency operation apparatus includes a grasping portion for grasping a treatment target living tissue, an electrode for supplying a high-frequency current to the living tissue, a high-frequency current supplying section that generates the high-frequency current necessary for treatment, a cable section that transmits the high-frequency current, an impedance measuring section for measuring an impedance value of the living tissue, a detecting section that detects that the impedance value reaches an impedance threshold at a time when moisture in the living tissue starts to evaporate, a measuring section that measures an output time of the high-frequency current after the detection, a storing section that stores a set time, and an output control section that performs control for stopping an output when the output time of the high-frequency current reaches the stored set time.03-14-2013
20130066237METHODS AND DEVICES FOR INFLAMMATION TREATMENT - Methods and devices are disclosed for controlled mediation and/or improvement of inflammation, inflammation associated with pain, and pain by delivering non-ablative thermal tissue damage to portions of a region of tissue including a volume of inflamed tissue, thereby activating the immune systems pain relief response to the tissue damage.03-14-2013
20120116270Ultrasonic Therapy Apparatus - An ultrasonic therapy apparatus having an oscillator connected to an electric power supplying unit through a cord and an elongated apparatus main body through which the cord passes in the longitudinal direction and holding the oscillator at a front end portion of the apparatus main body, in which the apparatus main body includes a base member having a holding unit that holds the oscillator and an accommodating groove that accommodates the cord, and a cover member that covers the accommodating groove, the base member and the cover member are separably locked by a front end locking portion provided in front of the front end portion and a base end locking portion provided at a base end portion of the apparatus main body.05-10-2012
20120116268Switched Resonant Ultrasonic Power Amplifier System - A switched resonant power amplifier system for ultrasonic transducers is disclosed. The system includes an amplifier that receives and processes a driver output signal for generating a drive signal that is provided to an ultrasonic device for controlling output of the ultrasonic device. An output control circuit receives and processes a signal related to a feedback signal generated by the ultrasonic device and a divider reference signal, and generates a compensated clock signal that is adjusted for at least one of phase and frequency differences between the received feedback signal and the divider reference signal. A compensated drive circuit receives and processes the compensated clock signal for generating the divider reference signal, and for generating the driver output signal.05-10-2012
20120116262CAM DRIVEN COUPLING BETWEEN ULTRASONIC TRANSDUCER AND WAVEGUIDE IN SURGICAL INSTRUMENT - A surgical instrument includes a body assembly, a waveguide, a transducer, and a coupling assembly. In some versions the coupling assembly translates the transducer to couple the transducer to the waveguide. For instance, a gear having arcuate troughs may engage pins on the transducer and/or waveguide to mate the transducer to waveguide. A pawl may selectively engage and prevent rotation of the gear. Alternatively, lever arms may cam the transducer into the waveguide. The lever arms may selectively couple to a casing to prevent decoupling of the transducer and waveguide. In another configuration, a locking tab can be slid and locked into a slot to couple the transducer and waveguide. Further still, levers with self-locking pins may engage and couple the transducer to the waveguide. In another version, a rotatable body portion may engage a tab on the transducer to rotate and couple the transducer to the waveguide.05-10-2012
20120116261SURGICAL INSTRUMENT WITH SLIP RING ASSEMBLY TO POWER ULTRASONIC TRANSDUCER - A surgical instrument includes a rotatable electrical coupling assembly having a first part and a second part that electrically couple and rotate relative to each other. The second part is carried by and rotates with a tube collar coupled to a transducer. A portion of the transducer is inserted through an aperture of the second part, but does not contact the second part. The first part of the assembly may electrically couple to the second part via pogo pins, brush contacts, or ball bearings. Alternatively, the first part may comprise conductive channels formed in the casing. The second part may comprise a rotatable drum with a conductive trace. In some versions, one or more components may comprise MID components. In another version, the rotatable electrical coupling assembly comprises a rotatable PC board and brush contact. Further still, a circuit board may be provided with the transducer inside a transducer casing.05-10-2012
20120116260SURGICAL INSTRUMENT WITH MOTORIZED ATTACHMENT FEATURE - An apparatus comprises an instrument body and transmission assembly. The instrument body comprises a motor, a switch, and an energy source (e.g., an ultrasonic transducer). The transmission assembly comprises an end effector, a transmission feature (e.g., an acoustic waveguide), and a switch engagement feature. The end effector includes an active feature (e.g., a harmonic blade) in communication with the energy source. The switch engagement feature is operable to mechanically couple the energy source with the transmission feature in response to the switch engagement feature triggering the switch. A yoke of the instrument body is configured to selectively engage a translating member of the transmission assembly. A release switch is operable to selectively disengage the yoke from the translating member.05-10-2012
20090254005ULTRASOUND ASSISTED TISSUE WELDING DEVICE - The present invention relates to ultrasound assisted tissue welding, more particularly, to a method and device utilizing ultrasound energy for effective closure and sealing of surgical incisions or other wounds. The device of the present invention comprises an ultrasound generator, an ultrasound transducer, a transducer tip at the distal end of the ultrasound transducer, and a radiation surface. A web such as gauze is placed over the incision. In an embodiment, the device may be used to bring the edges of the tissue to be sealed together as the device applies energy to the tissues. Ultrasonic waves emanating from the radiation surface pass through the web and seal the incision creating a continuous seam. The device may be used with or without additional adhesive materials or therapeutic agents.10-08-2009
20120232433ULTRASOUND NEUROMODULATION TREATMENT OF TINNITUS - Disclosed are methods and systems and methods for non-invasive neuromodulation using ultrasound to treat tinnitus. The neuromodulation can produce acute or long-term effects. The latter occur through Long-Term Depression (LTD) via training Included is control of direction of the energy emission, intensity, frequency, pulse duration, and phase/intensity relationships to targeting and accomplishing up regulation and/or down regulation.09-13-2012
20130165821Mechanical Wound Therapy for Sub-Atmospheric Wound Care System - A mechanical wound therapy (MWT) system includes a connection for a vacuum source, which is routed through an airtight covering to a porous material positioned over the wound. The porous material may be a tubing network interspaced by a netting material constructed of biologically inert or bioabsorbable material. Alternatively, the porous material may be a layered unified dressing in which layers of mesh, netting or thin perforated film are separated and fixedly attached to functional elements of the dressing (e.g., irrigation tubing) or spacers. The vacuum and irrigation systems may be completely separated. An airtight sealing layer or foldable adhesive sealing layer may seal the dressing and facilitate sealing the dressing to the wound margins. Additional modular devices such as a wound approximating system, positive pressure bladders and adjuvant therapy modules as well as enhanced monitoring technology can be added to synergistically increase the capabilities of each dressing.06-27-2013
20130165822METHODS FOR THERMALLY-INDUCED RENAL NEUROMODULATION - Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters of the neural fibers, of non-target tissue, or of the thermal energy delivery element, may be monitored via one or more sensors for controlling the thermally-induced neuromodulation. In some embodiments, protective elements may be provided to reduce a degree of thermal damage induced in the non-target tissues.06-27-2013
20100087758LAMINATED ULTRASONIC WAVEGUIDES FABRICATED FROM SHEET STOCK - A laminated ultrasonic waveguide and a method of fabrication thereof which comprises stamping at least two pieces of sheet stock to form stamped parts of the laminated ultrasonic waveguide. The stamped parts are then laminated together to form a laminated ultrasonic waveguide for transferring ultrasonic acoustic energy along a longitudinal axis of the laminated ultrasonic waveguide. In several disclosed embodiments, the laminated ultrasonic waveguide is part of an ultrasonic surgical instrument having an active tip end-effector which is placed in contact with tissue of a patient to couple ultrasonic energy transferred along the laminated ultrasonic waveguide to the tissue. The stamped pieces of sheet stock can also be stamped to form one or more channels extending along the length of the laminated ultrasonic waveguide. The laminated ultrasonic waveguide can also define a connector at a proximal end thereof to transfer ultrasonic energy into the laminated ultrasonic waveguide. In different embodiments, the laminated ultrasonic waveguide comprises first and second (and third or more) stamped pieces of sheet stock which are laminated together.04-08-2010
20120238919NERVE TREATMENT SYSTEM - In some examples, nerves surrounding arteries or leading to organs are targeted with energy sources to correct or modulate physiologic processes. In some examples, different types of energy sources are utilized singly or combined with one another. In some examples, bioactive agents or devices activated by the energy sources are delivered to the region of interest and the energy is enhanced by such agents or the agents are enhanced by the energy sources.09-20-2012
20120238917COMBINATION ULTRASOUND-PHOTOTHERAPY TRANSDUCER - A soundhead of a treatment device is provided that enables a volume of tissue located beneath the soundhead to simultaneously receive ultrasound and light stimulation. According to one embodiment, the soundhead includes an ultrasound transducer, a light source, and a faceplate extending across a face of the transducer for providing a tissue contacting and ultrasound energy coupling surface of the soundhead. The faceplate is transparent or translucent to the light generated by the light source. Alternate embodiments including externally mounted light sources are also disclosed.09-20-2012
20120238916ULTRASOUND CATHETER AND METHODS FOR MAKING AND USING SAME - Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and, in some embodiments, a guidewire tube extending through the lumen. A distal head for disrupting occlusions is coupled with the distal end of the ultrasound transmission member and is positioned adjacent the distal end of the catheter body. Some embodiments include improved features such as a bend in the catheter body for enhancing positioning and/or advancement of the catheter.09-20-2012
20120238915SOUND WAVE TREATMENT PLATFORM AND SOUND WAVE TREATMENT METHOD - A sound wave treatment platform is provided. The sound wave treatment platform includes a sound wave emitting module, a control module and a supporting component for receiving and supporting the sound wave emitting module. The sound wave emitting module includes a plurality of sound wave emitting devices for emitting non-focused sound waves. A sound wave treatment method is also provided. The sound wave treatment method includes the step of administering non-focused sound waves to a subject, wherein the non-focused sound waves are produced by a plurality of sound wave emitting devices.09-20-2012
20090131837Ultrasound Device - A method an apparatus for healing bone fractures comprises applying an ultrasound signal to a target site. The ultrasound signal comprises a generally uniform distribution of constructive interference positions in the target site.05-21-2009
20110282249REFLECTANCE-FACILITATED ULTRASOUND TREATMENT - Apparatus is provided that includes an ultrasound ablation system, which includes a reflection-facilitation element, configured to be placed at an extramyocardial site of a subject, and to provide an extramyocardial reflective region. The system further includes an ultrasound tool, which comprises at least one ultrasound transducer configured to be positioned within a heart chamber of the subject, and to ablate myocardial tissue by applying ultrasound energy to the myocardial tissue such that at least a portion of the transmitted energy is reflected by the reflective region onto the myocardial tissue. Other embodiments are also described.11-17-2011
20090088669Vacuum Disruption Apparatus With Triple Variable Intersecting Ultrasonic Beams - A vacuum disruption apparatus with triple variable intersecting ultrasonic beams, capable of disrupting a great number of cells efficiently without chemical loading. The apparatus includes a vacuum disruption vessel for containing and sealing a sample solution having living cells to be disrupted; at least three ultrasonic generation units for emitting ultrasonic beams toward the vacuum disruption vessel; and an ultrasonic modulation unit for varying the intensities and frequencies of ultrasonic from the ultrasonic generation units.04-02-2009
20120232437DEVICE FOR MODULATING PGC-1 EXPRESSION, AND TREATING DEVICE AND TREATING METHOD FOR ISCHEMIC DISEASE - A PGC-1 expression-modulating device (09-13-2012
20130023802APPARATUS AND METHOD FOR DESTRUCTION OF VASCULAR THROMBUS - A device for thrombolytic therapy is provided. The device includes an elongate catheter with a distal end portion and a proximal end portion and a first lumen extending through both distal and proximal end portions. The distal end portion of the catheter includes an echogenic tubular potion that defines or surrounds a portion of the first lumen. An expandable balloon coaxially surrounds the tubular portion. The tubular portion additionally includes a plurality of indentations defined upon an outer surface thereof.01-24-2013
20110301506ULTRASOUND PULSE SHAPING - In one embodiment of the present invention, an ultrasound catheter system comprising a catheter having at least one ultrasonic element; and a control system configured to generate power parameters to drive the ultrasonic element to generate ultrasonic energy is provided. The control system is configured to provide an ultrasonic pulse with a high pressure gradient with respect to time and/or distance. In another embodiment, a method of enhancing delivery of a therapeutic compound comprising delivering the therapeutic compound to a treatment site in a patient; and exposing the treatment site to an ultrasonic energy generated by an oscillating electrical signal pattern having a rise or fall rate greater than an sinusoidal pattern for the same amplitude and frequency is provided.12-08-2011
20100249669ULTRASONIC TREATMENT OF ADIPOSE TISSUE AT MULTIPLE DEPTHS - Methods and apparatus (09-30-2010
20100249668ULTRASONIC TRANSDUCER - An ultrasonic transducer has at least two sets of transducer units, with all the transducer units in each set having the same focus position and the transducer units in the different sets having different focus positions. Since the focus points of the sets of ultrasonic transducer units are distributed in a relatively large spatial range, the range of ultrasonic therapy can be increased even within the narrow and limited space of magnetic resonance imaging equipment.09-30-2010
20110288452SURGICAL INSTRUMENTS - A surgical device. The surgical device may comprise a transducer configured to provide vibrations along a longitudinal axis and an end effector coupled to the transducer and extending from the transducer along the longitudinal axis. The surgical device also may comprise a lower jaw extending parallel to the end effector. The lower jaw may comprise a clamp face extending toward the longitudinal axis. Also, the lower jaw may be slidable relative to the end effector to bring the clamp face toward a distal end of the end effector.11-24-2011
20090221938Method and Apparatus for Treatment of Adipose Tissue - The invention provides methods and apparatuses (09-03-2009
20110301508TRANSURETHRAL ULTRASOUND PROBE FOR TREATMENT OF PROSTATE12-08-2011
20110301507METHOD OF TREATING AN OCULAR PATHOLOGY BY APPLYING ULTRASOUND TO THE TRABECULAR MESHWORK AND DEVICE THEREOF - A phacoemulsificator for the removal of lens tissue, said phacoemulsificator comprising: 12-08-2011
20100331743APPARATUS AND METHOD FOR AN ULTRASONIC MEDICAL DEVICE OPERATING IN TORSIONAL AND TRANSVERSE MODES - The present invention provides an apparatus and a method for an ultrasonic medical device operating in a torsional mode and a transverse mode. An ultrasonic probe of the ultrasonic medical device is placed in communication with a biological material. An ultrasonic energy source is activated to produce an electrical signal that drives a transducer to produce a torsional vibration of the ultrasonic probe. The torsional vibration produces a component of force in a transverse direction relative to a longitudinal axis of the ultrasonic probe, thereby exciting a transverse vibration along the longitudinal axis causing the ultrasonic probe to undergo both a torsional vibration and a transverse vibration. The torsional vibration and the transverse vibration cause cavitation in a medium surrounding the ultrasonic probe to ablate the biological material.12-30-2010
20120010542ULTRASONIC FAT REDUCTION AND BODY SHAPING MACHINE - The invention discloses an ultrasonic fat reduction and body shaping machine that includes a treatment head (01-12-2012
20120010540SURGICAL APPARATUS - A surgical apparatus includes an output mode switching section configured to selectively switch an output mode of a power supply main body, that can output the energy to a probe and a jaw, in accordance with a moving state of a movable member. The output mode switching section is configured to switch the output mode such that a bipolar mode in which the probe and the jaw are driven as high-frequency electrodes is set when the jaw is in a closed state with respect to the probe and a single output mode in which the energy is output from only the probe is set when the jaw is in an open state with respect to the probe.01-12-2012
20110288449Method of lysing a thrombus - A thrombolytic method of dissipating a thrombus by an application of ultrasound of a frequency in a diagnostic range in combination with a microbubble contrast agent.11-24-2011
20110288451MEDICAL APPARATUS AND SURGICAL TREATMENT INSTRUMENT - A medical apparatus has a first device, a second device, a cable, a connection signal output portion and a main body apparatus. The first device includes a grasping portion, a probe connected to the grasping portion and capable of transmitting at least one of an ultrasound vibration and a high-frequency current, and a treatment portion provided at a distal end portion of the probe and for transmitting at least one of the ultrasound vibration and the high-frequency current transmitted by the probe, to living tissue. A second device includes a jaw member for holding living tissue between the treatment portion and the jaw member, a movable handle for holding the living tissue by moving the jaw member toward the treatment portion, and a recessed portion for being attachably and detachably engaged with the first device. The connection signal output portion outputs a connection signal indicating that the first device is connected to the recessed portion of the second device. The main body apparatus controls output of a drive signal for supplying at least one of an ultrasound vibration and a high-frequency current to the first device.11-24-2011
20110288450Time-Reversed Mirroring Electro-Magnetic Acoustic Treatment System - A time-reversal mirroring electromagnetic acoustic treatment system is disclosed where electro-magnetic signals are directed to a region of interest in or on a patient. The EM signals induce an internally sourced acoustic signal due to variations in conductivity of the target tissue. Acoustic data representative of the induced acoustic signal are collected and analyzed to develop a model of a measured conductivity topology representing the conductivity topology of the target tissue. Measured parameters associated with the measured conductivity topology and derived from the acoustic data can be used to generate a time-reversed mirror acoustic treatment signal that can be used to apply a therapeutic treatment to a target tissue within the region of interest.11-24-2011
20110295160SYSTEMS AND METHODS FOR MODULATING PRESSURE WAVE THERAPY - A processor-controlled, energy-based therapy apparatus includes a device configured to provide therapeutic energy to a patient and a processor that controls the output of the device. The output of the device is based on output profiles programmed into the processor. The output profiles include a therapeutic energy output profile and a ramp-up energy profile. The therapeutic energy output profile includes a desired target energy level and a therapeutic duration for controlling the output of the device during a therapeutic period. The ramp-up energy output profile includes an initial treatment energy level and a ramp-up duration for controlling the output of the device during a ramp-up period. The energy output specified by the ramp-up energy output profile incrementally increases over the ramp-up duration as a function of the desired target energy level and the ramp-up duration.12-01-2011
20120191019APPARATUS AND METHODS FOR NON-INVASIVE BODY CONTOURING - Methods and devices for applying high intensity focused ultrasound to modulate collagen in animal tissue (such as to disrupt collagen fibrils in a mammal, such as a human), particularly to enhance the aesthetic appearance of skin, and/or to otherwise improve skin conditions.07-26-2012
20120191018METHOD AND DEVICE FOR TREATING OSTEOARTHRITIS NONINVASIVELY - Methods and devices are provided for OA treatment of an affected area or joint. In one embodiment, the method may involve identifying a treatment site of the joint, and providing at least one transducer module at the treatment site. The at least one transducer module may be in operative communication with a signal generator module, and may include transducer(s) for delivering ultrasound signals. The method may also; involve stimulating (a) bone remodeling, (b) bone cells and associated; precursors, and/or (c) pericytes with the ultrasound signals delivered to the treatment site at a user-selected intensity.07-26-2012
20110201973ULTRASOUND COMPATIBLE RADIOFREQUENCY ABLATION ELECTRODE - Embodiments of the present invention are directed to an ultrasound compatible ablation electrode for use in ultrasound imaging guidance of ablation therapy using RF or the like. In one embodiment, an ultrasound compatible ablation catheter comprises a catheter body having a distal end and an ultrasonic transducer directing ultrasonic beams for imaging a target; and an ablation electrode connected to the catheter body, the ablation electrode having a plastic shell and a metallic coating on the plastic shell which are disposed in a path of the ultrasonic beams of the ultrasonic transducer between the ultrasonic transducer and the target, the metallic coating of the ablation electrode to be energized for ablation.08-18-2011
20090099486Ultrasonically Gas-Charged Reaction Accelerator - An apparatus comprises an ultrasound intensifier having an air/gas inlet, and a high powered non-contact ultrasound transducer, the ultrasound transducer directing ultrasound energy into the intensifier and methods of using the apparatus to increase the physical and/or chemical reactivity of a liquid or surface.04-16-2009
20090099483APPARATUS AND METHOD FOR ULTRASOUND TREATMENT - A transducer for generating an intensity pattern of ultrasound comprising: a plurality of elements independently excitable to radiate acoustic energy; and a controller that simultaneously excites some of the elements while leaving at least one element dormant and changes which element is dormant to change the intensity pattern.04-16-2009
20090005713Method and Device for Using Vibroacoustical Stimulation to Treat Target Tissue Areas of Living Organisms - A method and device for using topically applied acoustical vibrations to treat diseases and conditions in living organisms. This approach is non-invasive, and more specifically does not involve introducing chemicals or physically invading the organisms. One or more acoustical transducers are placed directly on the skin of the organism in certain locations, and specific vibration profiles designed to treat specific diseases and conditions are applied to the organism through the transducers. The treatment includes the regular application of various vibration pulse profiles that generally include sequences of pulses in which each pulse has a duration in the range of 0.5 to 10 seconds, is separated by rest periods in the range of 0.1 to 3 seconds, is modulated with an oscillatory signal in the frequency range of 1 Hz to 1,500 Hz, and has a pulse amplitude in the range of range from about 20 to 5000 microns.01-01-2009
20110130687Safety detection method for ultrasonic treatment device - A detection method for an ultrasonic treatment device is disclosed. A current value presently flowing through an output circuit of the ultrasonic treatment device is detected when a probe of the ultrasonic treatment device is in contact with a surface of a user's skin. Whether or not the change in the current values maintains within a predetermined current error range is determined, and whether or not a sampling holding time during which the change in the current values maintains within the current error range exceeds a predetermined time reference value is also determined. When the probe is determined to be under abnormal conditions according to the current error range, time reference value and the upper limit value of working time, the probe is stopped from generating ultrasonic energy, thereby lowering the risks for the user and preventing the user from injuries.06-02-2011
20100113983UTILIZING ULTRASOUND TO DISRUPT PATHOGENS - Provided are systems and/or methods that treat illnesses and conditions using ultrasound tuned to a resonant frequency of a target material with the assistance of computer processing. The ultrasound tuned to the resonance frequency of a target material destroys the target material without harming healthy material that surrounds the target material. A resonance frequency database can be employed to ensure that local healthy material surrounding a target has a natural resonance frequency dissimilar enough from the tuned resonance frequency.05-06-2010
20090149781Biomedical used multiple-channel hemispherical focused ultrasound phased array apparatus - The invention is to a biomedical used multiple-channel hemispherical focused ultrasound phased array apparatus. The invention comprises of a graphic user interface, digital multiple channel phase control kernel, multiple channel driving system, and impedance matching module, power feedback device, as well as the hemispherical low-frequency ultrasound phased array. The invention also serves as a good platform reference to develop a focused ultrasound system in the assisted brain drug delivery application.06-11-2009
20110264012COMPLIANT COUPLANT WITH LIQUID RESERVOIR FOR TRANSDUCER - An elastomeric pad structure coupled to an ultrasonic transducer provides excellent coupling and transmission for extradermal applications without requiring the glycerin gel couplant typically used for such applications. The material and shape of the face of the pad structure traps a small amount of liquid between the pad and the skin, providing an effective couplant not requiring further containment, rewetting, or clean-up. The elastomeric pad be releasably coupled to the ultrasonic transducer, and the various illustrative embodiments for coupling include the use of clips, adhesives, an adapter ring having a lip or grooves, a ring having pins for engaging holes in the elastomeric pad and the transducer, and a sleeve which employs pressure or friction to retain the elastomeric pad to the transducer. Uses for the system and method include extradermal applications such as ultrasonic bone growth stimulation through a window cut in a bone fracture cast.10-27-2011
20100087759APPARATUS AND METHOD FOR AN ULTRASONIC MEDICAL DEVICE WITH VARIABLE FREQUENCY DRIVE - An apparatus and method for an ultrasonic medical device with a variable frequency drive for ablating a biological material comprises an ultrasonic probe having a proximal end, a distal end and a longitudinal axis therebetween; a transducer that drives the ultrasonic probe over a variable frequency range, creating a transverse ultrasonic vibration along at least a portion of the longitudinal axis of the ultrasonic probe; a coupling engaging the proximal end of the ultrasonic probe to a distal end of the transducer; and an ultrasonic energy source engaged to the transducer that produces an ultrasonic energy, wherein driving the ultrasonic probe over the variable frequency range allows for the ultrasonic energy to propagate around a bend of the ultrasonic probe to ablate the biological material in communication with the ultrasonic probe.04-08-2010
20100268127Ultrasound Medical Systems and Related Methods - Ultrasound medical systems and related methods are described.10-21-2010
20090275864SURGICAL OPERATING APPARATUS - A surgical operating apparatus includes an ultrasonic transducer which generates ultrasonic vibration, a transducer cover including a storing section which stores the ultrasonic transducer, an electric contact portion provided on an outer peripheral surface of a distal end portion of the transducer cover, and an insulative projection portion which is provided at a distal end portion of the transducer cover and projects more radially outward than an outer peripheral surface of the electric contact portion.11-05-2009
20090275863SURGICAL TREATMENT APPARATUS - A handpiece of a surgical treatment apparatus includes a vibrating portion having an axial length being a length corresponding to one wavelength or above of the ultrasonic vibration, the vibrating portion includes a vibration generating portion formed on a proximal-end side of the vibrating portion and having an axial length being a length corresponding to a quarter wavelength of the ultrasonic vibration and an outside diameter, and a vibration transmitting portion formed on a distal-end side of the vibrating portion and having an axial length being a length corresponding to a three-quarter wavelength or above of the ultrasonic vibration, the vibration transmitting portion includes a reduced diameter portion arranged on the proximal-end side of the vibration transmitting portion, and an extending portion arranged on the distal-end side of the vibration transmitting portion and having an outside diameter smaller than the outside diameter of the vibration generating portion, and the operating portion is arranged in an accommodation space formed on a radially outer side of the extending portion along the extending portion in the handpiece.11-05-2009
20090198156ULTRASOUND MEDICAL TREATMENT SYSTEM AND METHOD - An ultrasound medical treatment system includes an ultrasound medical treatment transducer and a controller. Methods of the invention so control the medical treatment transducer. In one arrangement, the controller movingly controls the medical treatment transducer to emit ultrasound to thermally ablate patient tissue: 1) for a plurality of predetermined time intervals each associated with the medical treatment transducer movingly disposed at a different one of an equal number of predetermined positions, wherein a next-in-time time interval is associated with a position which is spatially non-adjacent to a position associated with a present-in-time time interval; or 2) for a predetermined time interval during which the transducer is continuously moved. In another arrangement, the transducer has an array of transducer elements and the controller activates different non-overlapping groups or different overlapping groups of transducer elements at different times.08-06-2009
20120109023SYSTEMS AND METHODS TO TARGET BLOOD VESSEL ADVENTITIA WITH TRANSCUTANEOUS FOCUSED ULTRASOUND - Systems and methods for maintaining the alignment of a therapeutic ultrasound applicator to a target site are described. Overlapping ultrasound signals are sent to a target tissue site and the echo detected. An algorithm is described for detecting tissue movement relative to the applicator based on comparison of the echo with a previously stored echo.05-03-2012
20120109022METHOD AND APPARATUS FOR ALTERING ACTIVITY OF TISSUE LAYERS - The present invention concerns ultrasonic methods and devices for altering activity of layers of natural--or of artificial tissues and organs, and for altering activity of particular components within said layers, while minimizing alterations in neighboring layers located deeper to—or outer to—treated layer. It is carried out by focused or non focused irradiation at certain angles and preferably via cooling medium, so to at least partially create surface waves propagating in the appropriate layers, and altering their activity, while leaving the other layers essentially intact. System can allow also monitoring of beam location and of effect. The device can be constructed for either superficial treatment, or minimal invasive treatment, or layered tissues and organs. It can be used as stand alone or add on device in cosmetic and clinical applications.05-03-2012
20100324458Ultrasound treatment system - An ultrasound treatment system comprises an ultrasonic transducer, a handpiece, a probe, a sheath, a clamping member, an operation unit, an operating member, a suction base, and a perfusion base. The ultrasonic transducer generates ultrasonic vibrations. The handpiece has the ultrasonic transducer incorporated therein. The probe is connected to the ultrasonic transducer for transmitting ultrasonic vibrations to a distal member realizing a stationary portion that is a treatment portion for treating a living tissue. The sheath serves as a protecting member for shielding the probe. The clamping member is opposed to the distal member at the distal end of the sheath for clamping a living tissue in cooperation with the distal member. The operation unit is manipulated for clamping a living tissue with the clamping member and distal member or freeing the living tissue therefrom.12-23-2010
20120109020METHODS FOR MODIFYING NEURAL TRANSMISSION PATTERNS - The invention generally relates to methods for modifying neural transmission patterns. In certain embodiments, methods of the invention involve noninvasively applying a first type of energy to a region of neural tissue, noninvasively applying a second type of energy to the region of tissue, such that the combined effect modifies a neural transmission pattern between cells of the neural tissue.05-03-2012
20120109019APPARATUS AND METHOD FOR ULTRASONIC SPINE TREATMENT - The present invention relates to an apparatus for therapeutically treating bone structure using ultrasound, and more particularly, the present invention relates to an apparatus with an attachment structure for treating bone injuries or a variety of musculoskeletal injuries and/or problems.05-03-2012
20120109018ENERGETIC MODULATION OF NERVES - A system for applying high intensity ultrasound energy to a nerve surrounding an artery of a patient includes a piezoelectric array comprising a plurality of ultrasound elements, a controller configured to individually control a phasing of each of the ultrasound elements, a platform on which the ultrasound elements are coupled, wherein the platform is configured to support at least a part of the patient, a programmable generator configured to generate an output power for at least one of the ultrasound elements, and a programmable processor configured to process a signal transmitted from one of the ultrasound elements and reflected back from tissue, and determine a tissue characteristic based on the reflected signal.05-03-2012
20110270136EFFICIENT ULTRASOUND FOCUSING - Ultrasound focusing may be improved by combining knowledge of the target tissue and/or focusing arrangement with focus measurements.11-03-2011
20100081971TREATMENT PLANNING SYSTEMS AND METHODS FOR BODY CONTOURING APPLICATIONS - Methods and system for treatment planning for non- and minimally-invasive alteration of body adipose tissue for reduction and contouring of body fat are described herein. Treatment plans can be generated by capturing current body part data (e.g., positioning, contour/shape, thickness of adipose tissue, etc.), determining desired outcome of treatment (e.g., percent reduction of adipose tissue thickness, degree of contour change, etc.), and determining treatment parameters to achieve desired results. Algorithms can be used to determine best-fit treatment parameters to use in treatment sessions. In some embodiments, the system can provide a predictive end-result image for communication to patient and/or for determining alteration of desired outcome. In various embodiments, real-time monitoring of feedback data can be used to determine treatment plan efficacy. Additional algorithms can provide real-time comparison of feedback data to anticipated feedback data, and can be used to change treatment parameters in real-time to achieve desired effects.04-01-2010
20090259150Device and Method for Detecting and Treating Lesions - A device for treating tissue comprises an enlongate probe and a light delivery unit illuminating a target area with light within a first wavelength band selected to enhance identification of target tissue in combination with an ultrasound crystal mounted at a distal end of the probe, the crystal being stimulated to treat target tissue identified using the light delivery unit.10-15-2009
20090281464Medical treatment system including an ancillary medical treatment apparatus with an associated data storage medium - A medical treatment system includes an electronic controller with a medical treatment apparatus, a data reader, an ancillary treatment apparatus used with the electronic medical treatment apparatus and a data storage medium associated with the ancillary treatment apparatus. The controller is configured to receive information from the data storage medium, and to control the medical treatment apparatus with medical treatment parameters compatible with the desired medical treatment and the ancillary treatment apparatus.11-12-2009
20090099482Ultrasonic Cerebral Infarction Therapeutic Apparatus - An ultrasonic cerebral infarction therapeutic apparatus that does not produce side effects of destruction of brain cells, occurrence of intracerebral hemorrhage, destruction of nerve cells, etc. by avoiding formation of a standing wave by interference between an irradiated beam of an ultrasonic wave irradiated to the inside of the cranium and its reflected beam. An ultrasonic probe cap is constructed by arranging a plurality of laminated small transducers each made up of a PVDF film, a PZT ceramic, or the like in a mosaic-like pattern or in other form on the inside of the cap and one or more transducers are selected and activated according to a thrombus position. As a high frequency for actuating a transducer, a continuous sinusoidal wave, a burst wave, or a pulse wave shall be used so that no standing wave may be produced inside the cranium.04-16-2009
20090281463THERAPY APPARATUS WITH SEQUENTIAL FUNCTIONING - A therapy apparatus for treating tissues by emission of focused ultrasound waves, includes a probe having a transducer formed by ultrasound elements distributed in several categories (N11-12-2009
20080281236Devices and methodologies useful in body aesthetics - A methodology and system for lysis or induction of apoptosis in cellulite and fat including directing ultrasonic energy at a multiplicity of target volumes within the region, which target volumes contain cellulite and fat, thereby to selectively lyse or induce apoptosis in the cellulite and fat in the target volumes and generally not lyse or not induce apoptosis in non-cellulite and non-fat tissue in the target volumes and computerized tracking of the multiplicity of target volumes notwithstanding movement of the body.11-13-2008
20090299235Ultrasonic Endometrial Cryoablation Device - The present invention relates to an ultrasound assisted cryogenic surgical instrument, more particularly, to methods and devices utilizing ultrasound energy for treatment of the endometrium to control heavy uterine bleeding (menorrhagia) or other conditions. The device of the present invention comprises an ultrasound generator, an ultrasound transducer, a transducer tip at the distal end of the ultrasound transducer, and a radiation surface. Ultrasonic radiation is directed into the tissue being ablated. A cryogenic solution, is circulated through the ultrasound tip to transfer thermal energy away from the tissue to freeze the tissue being ablated by providing a synergistic effect with the ultrasonic radiation.12-03-2009
20090299234FAT REMOVER - A fat remover is disclosed, which comprises an upper main body including a plurality of connection terminals, a lower main body including an upper plate having a plurality of female rivets transmitting ultrasonic signals and low-frequency signals by contact with the connection terminals, a cup body having an opened bottom surface, a rubber plate interposed between the upper plate and the cup body, and a second lower plate inserted in the bottom surface of the cup body, and a skin contact sensor protruded on an inner lower part of the lower main body together with the ultrasonic vibration plate and the low-frequency vibration plate. Accordingly, the fat remover separately has the ultrasonic vibration plate and the low-frequency vibration plate, and performs fat removal after confirming a close contact between the skin and the vibration plates by the skin contact sensor, by applying stimulus to the skin contacting the vibration plates.12-03-2009
20120296239Destruction of Vessel Walls for Energy-Based Vessel Sealing Enhancement - An end effector assembly for use with an electrosurgical instrument is provided. The end effector assembly includes a pair of opposing jaw members configured to grasp tissue therebetween, at least one jaw member adapted to connect to a source of electrosurgical energy to seal tissue disposed between jaw members during a sealing process. At least one of the jaw members includes an activator configured to selectively impart mechanical perturbations to the at least one jaw member during the sealing process.11-22-2012
20110270138ULTRASOUND MACRO-PULSE AND MICRO-PULSE SHAPES FOR NEUROMODULATION - Disclosed are methods and systems for non-invasive ultrasound stimulation of neural structures, whether the central nervous systems (such as the brain), nerve roots, or peripheral nerves using macro- and micro-pulse shaping. Which macro-pulse and micro-pulse shapes are most effect depends on the target. This can be assessed either by functional results (e.g., doing motor cortex stimulation and seeing which macro- and micro-pulse shape combination causes the greatest motor response) or by imaging (e.g., PET of fMRI) results.11-03-2011
20110270137METHOD AND SYSTEM FOR TREATING SKIN TISSUE - A device for treating a skin tissue is disclosed. The device comprises a device body having an anterior compartment and being formed with at least one suction port, and an ultrasound unit configured for generating an ultrasound wave into the anterior compartment. When an under pressure is formed in the suction port, the skin tissue is drawn by vacuum into the anterior compartment and irradiated by the ultrasound wave to form a focal spot optionally and preferably at a distance of from about 0.2 mm to about 4 mm below an external surface of the skin tissue.11-03-2011
20080275370APPARATUS AND METHOD FOR TREATING VISUAL DISORDERS - In one embodiment, an apparatus includes an elongate body having a proximal end and a distal end and an ultrasound transducer coupled to the distal end of the elongate body. A cooling member is coupled to the ultrasound transducer. The cooling member and/or the ultrasound transducer is configured to directly contact an outer surface of an eye such that ultrasound energy can be applied to a targeted portion of the eye. A method includes disposing a medical device such that a distal end of the medical device is in contact with an outer surface of an eye. The medical device includes an elongate body and an ultrasound transducer coupled to a distal end of the elongate body. Ultrasound energy is applied to a targeted portion of the eye while the medical device is disposed in contact with the outer surface of the eye to reshape the cornea of the eye.11-06-2008
20110208095METHOD FOR MODIFYING GLOMERULAR PERMEABILITY AND FUNCTION WITH FOCUSED ULTRASOUND - A method for noninvasively changing the permeability of a region of a subject that includes a desired tissue is provided. More specifically, low-power focused ultrasound (FUS) is employed to alter the permeability of the glomerulus so as to alter the glomerular ultrafiltration coefficient. By employing FUS after administering a microbubble contrast agent to a subject, glomerular filtration is temporarily increased and the clearance of larger molecules, which are normally not filtered by the kidney, is allowed. This method offers new treatment opportunities for renal disease management.08-25-2011
20100298743THERMALLY-ACTIVATED COUPLING ARRANGEMENTS AND METHODS FOR ATTACHING TOOLS TO ULTRASONIC SURGICAL INSTRUMENTS - An ultrasonic surgical instrument that has a waveguide that protrudes distally from the handpiece and a surgical tool that is configured to be coupled to the waveguide upon application of thermal energy to the waveguide or the surgical tool.11-25-2010
20100137752Medical Apparatus For Treatment Of The Human Or Animal Body By Mechanical Pressure Waves Or Shock Waves - A medical apparatus for treatment of the human or animal body by mechanical pressure waves or shock waves, comprises a device designed to generate the pressure waves or shock waves. The device for generating the pressure waves or shock waves have at least one applicator part which can be subjected to impacts at a proximal end in order to generate the pressure waves or shock waves and, at a distal end, applies the pressure waves or shock waves into the body. The apparatus is additionally designed to generate outside the body, and to apply into the body, at least one further physiological action parameter chosen from the group consisting of electrical current, electro-magnetic waves, in particular light, ultrasound and/or a further mechanical action.06-03-2010
20120296241ULTRASOUND NEUROMODULATION FOR TREATMENT OF AUTISM SPECTRUM DISORDER AND ALZHEIMERS DISEASE AND OTHER DEMENTIAS - Disclosed are methods and systems and methods for non-invasive neuromodulation using ultrasound for the Treatment of Autism Spectrum Disorders and Alzheimer's Disease and other dementias. The neuromodulation can produce acute or long-term effects. The latter occur through Long-Term Depression (LTD) and Long-Term Potentiation (LTP) via training. Included is control of direction of the energy emission, intensity, frequency, pulse duration, firing pattern, and phase/intensity relationships to targeting and accomplishing up regulation and/or down regulation.11-22-2012
20120296240ULTRASOUND EYE BAG TREATMENT - A method is provided comprising placing an energy source coupled to a first support structure, at a first location on skin of an eyelid and placing a second structure at a second location on the skin of the eyelid, the second location being farther from the eye than is the first location. A portion of skin of the eyelid and underlying tissue is held between the first and second structures and treatment energy is transmitted from the energy source, from the first location away from the eye, through the tissue, toward the second location on the skin of the eyelid, while withholding transmission of treatment energy from the second location on the skin of the eyelid, toward the eye, through the portion of tissue, toward the first location on the skin of the eyelid. Other embodiments are also described.11-22-2012
20110208094ULTRASOUND NEUROMODULATION OF THE RETICULAR ACTIVATING SYSTEM - Disclosed are methods and systems and methods for neuromodulation of the Reticular Activating System using ultrasound to produce acute effects or Long-Term Potentiation (LTP) or Long-Term Depression (LTD). Included is control of direction of the energy emission, intensity, pulse duration, frequency, and phase/intensity relationships to targeting and accomplishing up-regulation and/or down-regulation. The invention can be applied for a variety of clinical purposes such as reversibly putting a patient to sleep or waking them up (for example, for the purpose of anesthesia) or reversibly putting a patient into a coma (for example for the purpose of protecting or rehabilitating the brain of the patient after a stroke or head injury).08-25-2011
20100137753SKIN MASSAGE DEVICE - A skin massage device having a handset connected to a machine body. The handset in turn has a chamber closed by a deformable membrane which adheres to a patient's skin by virtue of a vacuum generated in the chamber by a vacuum generating device. The device also has an electronic device for producing a variable vacuum in the chamber to deform the membrane and so lift, fold, compress, and smooth the patient's skin as to perform the massage cycle set by the operator.06-03-2010
20080281237METHODS AND SYSTEMS FOR COUPLING AND FOCUSING ACOUSTIC ENERGY USING A COUPLER MEMBER - An exemplary system for coupling acoustic energy using an encapsulated coupler member comprises a display or indicator, a control system, a probe, and a coupler member. This invention provides a coupler member adjustably configured to perform at least one of (i) providing a standoff, (ii) focusing or defocusing energy, and (iii) coupling energy. An exemplary gel coupler member is configured to hold the shape of a lens geometry. In one aspect of the present invention, gel coupler member comprises water, glycerol, and polyvinyl alcohol, and exhibits an increased desiccation time and shelf life when compared to the prior art. The probe can comprise various probe and/or transducer configurations. In an exemplary embodiment, the probe delivers focused, unfocused, and/or defocused ultrasound energy to the region of interest. Imaging and/or monitoring may alternatively be coupled and/or co-housed with an ultrasound system contemplated by the present invention.11-13-2008
20080287838Switched Resonant Ultrasonic Power Amplifier System - A switched resonant power amplifier system for ultrasonic transducers is disclosed. The system includes an amplifier that receives and processes a driver output signal for generating a drive signal that is provided to an ultrasonic device for controlling output of the ultrasonic device. An output control circuit receives and processes a signal related to a feedback signal generated by the ultrasonic device and a divider reference signal, and generates a compensated clock signal that is adjusted for at least one of phase and frequency differences between the received feedback signal and the divider reference signal. A compensated drive circuit receives and processes the compensated clock signal for generating the divider reference signal, and for generating the driver output signal.11-20-2008
20080312561Mechanical Manipulator for Hifu Transducers - A mechanical manipulator (12-18-2008
20110009779 Method Of Treating An Ocular Pathology By Applying High Intensity Focused Ultrasound and Device Thereof - The present invention relates to a method of treating an ocular pathology by generating high intensity focused ultrasound onto at least one eye's area, said method comprises at least the following steps of: —positioning onto the eye a device capable of directing high intensity focused ultrasound onto at least one annular segment, —and generating high intensity focused ultrasound energy onto said segment to treat at least one annular segment in the eye.01-13-2011
20090264798SYSTEM AND METHOD FOR CONTROLLING ENERGY DELIVERY USING LOCAL HARMONIC MOTION - A system and method for control of energy application to a target location based on a measured localized harmonic motion is disclosed. The system includes a first energy source configured to deliver a beam of energy to a subject to induce mechanical vibration of a desired region, a second energy source configured to deliver a second beam of energy into the desired region, and a receiver configured to receive echo signals from the desired region indicative of reflected energy from the second energy source. The system also includes a computer programmed to analyze at least one of amplitude, phase, and frequency of the vibration of the desired region indicated by the received echo signals, monitor the amplitude, phase, and/or frequency of the vibration in the desired region during application of the beam of energy, detect a change in the amplitude, phase, and/or frequency of the vibration in the desired region and, if the change exceeds a pre-determined size and rate, generate an alert.10-22-2009
20080208084Systems and methods for applying ultrasound energy to increase tissue perfusion and/or vasodilation without substantial deep heating of tissue - Systems and methods apply ultrasound energy to achieve vasodilation and/or to increase tissue perfusion without causing substantial deep tissue heating.08-28-2008
20080287837ULTRASOUND MEDICAL SYSTEM AND METHOD - An ultrasound medical system includes an interstitial end effector. The interstitial end effector is interstitially insertable into patient tissue, includes at least one medical-treatment ultrasound transducer, and includes at least one end-effector-tissue-track ablation device. One method for ultrasonically treating a lesion in a patient includes the steps of obtaining the interstitial end effector and inserting it into the patient creating a tissue track which is surrounded by patient tissue and which ends at the distal end of the inserted interstitial end effector. Other steps include ultrasonically ablating the lesion using the at-least-one medical-treatment ultrasound transducer, using the at-least-one end-effector-tissue-track ablation device to ablate the patient tissue surrounding the tissue track along substantially the entire tissue track, and withdrawing the end effector from the patient.11-20-2008
20080287836Non-invasive ultrasonic body contouring - A methodology and system for lysing adipose tissue including directing ultrasonic energy at a multiplicity of target volumes within the region, which target volumes contain adipose tissue, thereby to selectively lyse the adipose tissue in the target volumes and generally not lyse non-adipose tissue in the target volumes and computerized tracking of the multiplicity of target volumes notwithstanding movement of the body.11-20-2008
20120143098METHOD AND SYSTEM FOR TREATING CELLULITE - A method and system for providing ultrasound treatment to a deep tissue that contains a lower part of dermis and proximal protrusions of fat lobuli into the dermis. The invention delivers ultrasound energy to the region creating a thermal injury and coagulating the proximal protrusions of fat lobuli, whereby eliminating the fat protrusions into the dermis. The invention can also include ultrasound imaging configurations using the same or a separate probe before, after or during the treatment. In addition various therapeutic levels of ultrasound can be used to increase the speed at which fat metabolizes. Additionally the mechanical action of ultrasound physically breaks fat cell clusters and stretches the fibrous bonds. Mechanical action will also enhance lymphatic drainage, stimulating the evacuation of fat decay products.06-07-2012
20120143100EXTENDED DEPTH-OF-FOCUS HIGH INTENSITY ULTRASONIC TRANSDUCER - Compound ultrasonic transducers are disclosed that include multiple transducer elements configured to have overlapping or consecutive depths of focus in an axial direction. Embodiments of such transducers can be composed of a concentric disc- and one or more annular-type elements and each element has a different radius of curvature to produce multiple focal zones (depths-of focus) upon excitation. Exemplary embodiments include a concentric disc- and one annular-type elements, with each element has a different radius of curvature, which are referred to herein as a dual-focus therapeutic ultrasound transducer (DFTUT). Method of directing ultrasonic energy to a target area and thereby aligning ultrasonic focal zones (depths-of focus) are also disclosed. Two or more transducer elements can each be configured to produce a different focal zone at the target area, such as targeted tissue.06-07-2012
20080269648Method for increasing saliva and tear production with ultrasound - A non-invasive apparatus and method for increasing saliva and tear production from the salivary and lacrimal glands with the application of high frequency low intensity ultrasound. An ultrasound transducer coated with connecting gel placed in contact with the facial tissues transmitting 1.5 MHz frequency ultrasound pressure waves into the tissues and into the glands. The time-averaged intensity of the ultrasound pressure waves is typically limited to approximately 30 milliwatts per square centimeter to avoid tissue heating.10-30-2008
20080269649Device and method for preparing a recess in a bone - A punching device for preparing a recess in a bone has a punching tool usable for such a punching device. An implant usable with the punching tool is provided and a method for preparing a recess in a bone are disclosed. The punching device comprises an ultrasonic sonotrode and a punching tool which is fixable to the sonotrode at its proximal extremity. At its distal extremity, the punching tool has a thin-walled portion having a non-rotational symmetric cross-section. By ultrasonic vibration of the punching tool, the thin-walled portion can be forced into a bone thereby preparing a recess of which is not rotationally symmetric. Subsequently, an implant can be held in such recess. Due to its lack of rotational symmetry, the implant may absorb rotational forces around its longitudinal axis.10-30-2008
20090030351Multiple end effectors ultrasonic surgical instruments - A surgical instrument includes a transducer configured to produce vibrations along a longitudinal axis at a predetermined frequency. The transducer includes a first end and a second end. A first resonator portion includes a first end coupled to the first end of the transducer. The first resonator includes a second end adapted to receive a first ultrasonic transmission waveguide. A second resonator portion includes a first end coupled to the second end of the transducer. The second resonator includes a second end adapted to receive a second ultrasonic transmission waveguide.01-29-2009
20090082703Method and apparatus for the treatment of tendon abnormalities - The present disclosure relates to a method of treating abnormalities in a tendon through the use of high intensity therapeutic ultrasound (HITU) energy.03-26-2009
20100274160SWITCHING STRUCTURE AND SURGICAL EQUIPMENT - A switching structure, which controls driving of equipment, includes a handle unit which is provided on the equipment and is held by a user, a switch operation section which is provided on the handle unit and includes a pressure reception portion which is pressed by the user, and a support portion which supports the pressure reception portion such that the pressure reception portion is pivotable about a pivotal center within the handle unit, relative to the handle unit, and also supports the pressure reception portion such that the pressure reception portion can be pushed from a desired direction toward the pivotal center of the pressure reception portion, when the user presses the pressure reception portion.10-28-2010
20120197165APPARATUS AND METHOD FOR MOUNTING A THERAPEUTIC DEVICE - An apparatus for ultrasonically treating an injury in conjunction with an orthopaedic cast is disclosed. The apparatus includes a portable self-contained main operating unit, a support fixture, an ultrasonic transducer treatment head module, and casting material for attaching the support fixture to the orthopaedic cast. The support fixture is configured and adapted for attachment to the orthopaedic cast adjacent an external site corresponding to an internal injury remote from the main operating unit. The support fixture has a body and at least one mesh projection extending from the body. The ultrasonic transducer treatment head module is operatively connected to the main operating unit and detachably engaged with the body of the support fixture. At least a portion of the casting material impregnates the mesh projection to attach the support fixture to the cast.08-02-2012
20090177123Methods for treating inflammatory disorders - The invention provides methods for treating inflammatory disorders by administering low frequency ultrasound energy to decrease the inflammatory response. Exemplary inflammatory disorders are rheumatoid disorders including, but not limited to, rheumatoid arthritis, juvenile arthritis, bursitis, gout, spondylitis, scleroderma, Still's disease, and vasculitis.07-09-2009
20090005710Ultrasonic Equipment for Treatment of Osteoarthritis - The present invention relates to an ultrasonic device for the treatment of arthritis, and more particularly, to an ultrasonic device for the treatment or prevention of degenerative arthritis, which is so structured that it generates ultrasonic waves with an intensity of 200-800 mW/cm2 and applies low-intensity ultrasonic energy of 100-400 mW/cm2 to cartilage cells deep in the skin's dermis. The inventive ultrasonic device comprises: a main control unit including an ultrasonic oscillation control unit allowing the generation of ultrasonic waves with a frequency of 0.1-5 MHz and low intensity of 200-800 mW/cm2; an ultrasonic generator for generating ultrasonic waves according to the control state of the main control unit; an ultrasonic vibrator that vibrates according to ultrasonic waves inputted from the ultrasonic generator; and a probe for transferring ultrasonic vibration to a joint to be treated. The ultrasonic device can induce the regeneration of cartilage tissue by the activation of cartilage tissue, and thus, can fundamentally treat degenerative arthritis.01-01-2009
20080306414Method and Apparatus for Guidance and Application of High Intensity Focused Ultrasound for Control of Bleeding Due to Severed Limbs - An ultrasonic diagnostic and therapy system is described for stopping the bleeding of severely damaged blood vessels or vessels severed in a limb amputation. A cuff (12-11-2008
20110224582METHODS RELATED TO DIVERTING MATERIAL IN BLOOD FLOW AWAY FROM THE HEAD - A system for directing ultrasonic energy through blood flow in the aorta of a patient proximate the origins of the great vessels to the head of the patient to divert material in the blood flow from the origins of the great vessels. The system includes a first device configured for introduction into the cardiovascular system of the patient and positioning proximate the origins of the great vessels to the head of the patient, and at least one ultrasonic energy emitter carried by the first device.09-15-2011
20110230793Treatment of Alopecia with ultrasound - A method for the treatment of alopecia and in particular the problem of male-pattern baldness. By application of controlled ultrasound exposures to specific regions in the skin tissue, a physiological response will develop which causes cells in the hair follicle to increase in number, and/or new follicles to form or multiply in response to controlled damage to existing cells, leading to new hair follicles and/or increased shaft thickness in existing hair follicles resulting in more robust hair growth.09-22-2011
20110230795ULTRASONIC METHOD AND DEVICE FOR WOUND TREATMENT - An apparatus and method are provided for applying a medicament to tissue, and delivering ultrasonic energy from a non-contact distance from the tissue to the medicament and to the tissue, wherein the ultrasonic energy has intensity capable of penetrating the wound tissue to a beneficial depth to provide a therapeutic effect to the tissue, and of sonicating the medicament for causing the medicament to penetrate the tissue to a beneficial depth to provide a therapeutic effect to the tissue.09-22-2011
20110230794ULTRASOUND APPLICATION DEVICE - A high power ultrasound application device (09-22-2011
20090099485ULTRASOUND STANDING WAVE METHOD AND APPARATUS FOR TISSUE TREATMENT - Described herein are devices and methods for treatment of tissue with ultrasound standing waves. Vacuum-based or mechanical clamping resonators are proposed aimed at retaining tissue therewithin and in acoustic contact with ultrasound transducer means such as a single tubular piezotransducer or a pair of plane-parallel transducers. Ultrasound standing wave field is then applied at single or alternating resonance frequencies creating nodal patterns allowing expanding the area of treatment as compared with conventional devices. Real-time feedback is provided to monitor the progression of treatment. Additional device provisions include acoustic gel injector means, vacuum release means, indicator means for treatment completion, etc. This invention is particularly useful for non-invasive skin and adipose tissue treatments.04-16-2009
20120078140Method and Apparatus for Removing Blood Clots and Tissue from the Patient's Head - Methods and apparatus for removing blood clots and tissue from intracranial space of the patient's head using an ultrasound device under visualization guidance to locate, dissolve and remove the blood clots outside the patient's head are provided. One or more pharmacologic agents may be delivered to the treatment area to further facilitate removal of the blood clots or other tissue.03-29-2012
20120078139SURGICAL GENERATOR FOR ULTRASONIC AND ELECTROSURGICAL DEVICES - A generator is disclosed to generate a drive signal to a surgical device. The generator includes an ultrasonic generator module to generate a first drive signal to drive an ultrasonic device, an electrosurgery/radio frequency (RF) generator module to generate a second drive signal to drive an electrosurgical device, and a foot switch coupled to each of the ultrasonic generator module and the electrosurgery/RF generator module. The foot switch is configured to operate in a first mode when the ultrasonic device is coupled to the ultrasonic generator module and the foot switch is configured to operate in a second mode when the electrosurgical device is coupled to the electrosurgery/RF generator module. The generator further includes a user interface to provide feedback in accordance with the operation of any one of the ultrasonic device and the electrosurgical device in accordance with a predetermined algorithm.03-29-2012
20080319356PULSED CAVITATIONAL ULTRASOUND THERAPY - Therapy methods using pulsed cavitational ultrasound therapy can include the subprocesses of initiation, maintenance, therapy, and feedback of the histotripsy process, which involves the creation and maintenance of ensembles of microbubbles and the use of feedback in order to optimize the process based on observed spatial-temporal bubble cloud dynamics. The methods provide for the subdivision or erosion of tissue, liquification of tissue, and/or the enhanced delivery of therapeutic agents. Various feedback mechanisms allow variation of ultrasound parameters and provide control over the pulsed cavitational process, permitting the process to be tuned for a number of applications. Such applications can include specific tissue erosion, bulk tissue homogenization, and delivery of therapeutic agents across barriers.12-25-2008
20090112131BODY SCULPTING DEVICE AND BODY SCULPTING SYSTEM USING THE SAME - A body sculpting device and a body sculpting system are disclosed which can sculpt body areas, such as the abdomen, thighs, arms, etc., by burning fat stored in the body and massage the face and the soles of the feet, according to a use's selection. The body sculpting system includes a control box, a stand, an obesity management unit, and a probe.04-30-2009
20090209885ABLATIVE ULTRASONIC-CRYOGENIC APPARATUS - An ablative apparatus that can be used to treat atrial fibrillation and other cardiac arrhythmias by ablating cardiac tissue is disclosed. When the distal end of the apparatus reaches the tissue to be ablated, an ablation probe driven by a transducer is vibrated. Scratching the tissue with abrasive members, the vibrating ablation probe is capable of mechanically ablating tissues. This mechanical ablation may be utilized to penetrate epicardial fat, thereby exposing the underlying myocardium. The ablative apparatus may then be used subject the exposed myocardium to mechanical ablation, cryoablation, ultrasonic ablation, and/or any combination thereof.08-20-2009
20110144544ULTRASOUND TRANSDUCER ASSEMBLY AND METHODS OF USING - An ultrasound transducer assembly for adjustably directing a beam of ultrasound energy to a region of interest is provided. The ultrasound transducer assembly comprises a therapy transducer, a beam enhancement component that adjusts one or more parameters of the ultrasound beam, wherein the beam enhancement component is in operative association with the therapy transducer, and a component controller operatively coupled to the beam enhancement component for controlling the beam enhancement component.06-16-2011
20120197163PATTERNED CONTROL OF ULTRASOUND FOR NEUROMODULATION - Disclosed are methods and devices for ultrasound-mediated non-invasive deep brain neuromodulation impacting one or a plurality of points in a neural circuit using patterned inputs. These are applicable whether the ultrasound beams intersect at the targets or not. Depending on the application, this can produce short-term effects (as in the treatment of post-surgical pain) or long-term effects in terms of Long-Term Potentiation (LTP) or Long-Term Depression (LTD) to treat indications such as neurologic and psychiatric conditions. The ultrasound transducers are used with control of frequency, firing pattern, and intensity to produce up-regulation or down-regulation.08-02-2012
20090247912EPICARDIAL ABLATION USING FOCUSED ULTRASOUND - Apparatus for treating cardiac arrhythmias includes an ultrasonic ablation device incorporating an ultrasonic emitter (10-01-2009
20090254006ULTRASOUND ASSISTED TISSUE WELDING METHOD - The present invention relates to ultrasound assisted tissue welding, more particularly, to a method and device utilizing ultrasound energy for effective closure and sealing of surgical incisions or other wounds. The device of the present invention comprises an ultrasound generator, an ultrasound transducer, a transducer tip at the distal end of the ultrasound transducer, and a radiation surface. A web such as gauze is placed over the incision. In an embodiment, the device may be used to bring the edges of the tissue to be sealed together as the device applies energy to the tissues. Ultrasonic waves emanating from the radiation surface pass through the web and seal the incision creating a continuous seam. The device may be used with or without additional adhesive materials or therapeutic agents.10-08-2009
20080312562Method and Apparatus for Guidance and Application of High Intensity Focused Ultrasound for Control of Bleeding Due to Severed Limbs - An ultrasonic diagnostic and therapy system is described for stopping the bleeding of severely damaged blood vessels or vessels severed in a limb amputation. A cuff is attached to the stump of the severed limb which contains a diagnostic transducer array and a HIFU transducer. The diagnostic transducer surveys the tissue of the severed limb, searching for a Doppler flow signal. When a Doppler flow signal is detected, the range to and coordinates of the sample volume where the flow was detected are determined, as well as the flow velocity. This information is supplied to a HIFU therapy transducer controller, which controls the HIFU transducer to transmit focused ultrasound to the sample volume of the flow locus, the center of the lumen of a blood vessel. The focused ultrasound heats and coagulates blood in the severed vessel to stem the bleeding. Heat dissipation due to the blood flow is reduced by tracking and continuously heating the same bolus of blood as it flows, or by heating a significant length of the blood vessel instead of a fixed spot in the vessel.12-18-2008
20090318837SYSTEM AND METHODS FOR DESTROYING ADIPOSE TISSUE - Methods and systems for the destruction of adipose tissue are disclosed. A method is provided for creating a surface map corresponding to a volume of adipose tissue for noninvasive treatment, and additional methods are provided for the treatment of the adipose tissue.12-24-2009
20090275865ULTRASOUND TREATMENT CLAMP - The present invention relates to an ultrasound treatment clamp. The ultrasound treatment clamp comprises ultrasound therapy applicators and handles connected to the ultrasound therapy applicators. The handles are clamp-shaped. The two ultrasound therapy applicators with their central axes overlapping each other are mounted face to face on the two clamps of the clamp-shaped handles respectively. A parallel moving mechanism for keeping the two ultrasound therapy applicators in parallel when moving along with clamps is connected between the two clamps. The present invention has a compact structure, a convenient operation, a low treatment cost, a capability of quickly causing a coagulative necrosis of the diseased part. Furthermore, the present invention has an abroad use in treating many kinds of diseases.11-05-2009
20100152625EXTRACORPOREAL ULTRASONIC MEDICAL DEVICE - Ultrasonic devices for preventing microbubbles and/or microparticles from reaching the brain during a PCI or cardiovascular surgery. Devices 06-17-2010
20100152624APPARATUS AND METHOD FOR MOUNTING A THERAPEUTIC DEVICE - An apparatus (06-17-2010
20100160837BROAD-AREA IRRADIATION OF SMALL NEAR-FIELD TARGETS USING ULTRASOUND - An ultrasonic transducer system for treating a portion of tissue. The ultrasonic transducer system includes a frequency generator, an ultrasonic transducer, and a transmitter element. The transducer receives an AC voltage from the frequency generator and produces an ultrasonic energy pulse at an ultrasonic frequency for a pulse width. The transmitter element is coupled to the transducer and is for irradiating a portion of skin tissue. The transmitter element has a chilled surface in contact with the skin tissue and an acoustic aperture for producing a substantially collimated energy beam. The beam has a width greater than 4 mm.06-24-2010
20100185126ULTRASONIC ASSEMBLY WITH ADJUSTABLE FLUID LENS - An ultrasonic assembly suited for attachment to a catheter, e.g. for medical treatment. The ultrasonic assembly includes an adjustable ultrasonic focus mechanism arranged in connection with the ultrasonic transducer to adjust focus of ultrasonic waves generated by the transducer. The ultrasonic focus mechanism includes a fluid focus lens with at least two fluids separated by an interface such that ultrasonic waves are substantially reflected at the interface. At least two electrodes are arranged in connection with the fluid focus lens so as to allow adjustment of the interface shape, e.g. a curvature of the interface, when a voltage is applied to the electrodes. In preferred embodiments the electrodes are arranged so as to allow adjustment of the fluid focus lens in an elevation direction as well as in a radial direction. In simple embodiments with rotational symmetric geometry with the transducer positioned in the centre of the fluid focus lens, ultrasonic waves can be focused in an annular ring. This is e.g. suitable for ablative or coagulative necrotic treatment of human tissue, e.g. for atrial fibrillation treatment. In some embodiments, the assembly has a number of separate individually adjustable fluid focus lens compartments allowing a more detailed control of the ultrasonic focus pattern.07-22-2010
20120143096Cosmetic method for promoting recovery of skin barrier function using sound wave having a specific frequency - The present invention provides a cosmetic method for promoting the recovery of skin barrier function, comprising applying a sound wave having a frequency of 10,000 to 50,000 Hz to the skin.06-07-2012
20110060255THERAPEUTIC ULTRASOUND TRANSDUCER CHIP WITH INTEGRATED ULTRASOUND IMAGER AND METHODS OF MAKING AND USING THE SAME - A therapeutic ultrasound device may include a substrate, at least one high power capacitive micromachined ultrasonic transducer, and at least one imager transducer comprising a capacitive micromachined ultrasonic transducer. The at least one high power capacitive micromachined ultrasonic transducer and the imager transducer may be monolithically integrated on the substrate.03-10-2011
20110060254PORTABLE PHYSIS-STIMULATING DEVICE FOR PROMOTING GROWTH WITH TWO-PHASE ULTRASONIC VIBRATION GENERATORS AND LED ELEMENTS - Disclosed herein is a growth plate stimulation-type portable growth promotion apparatus including two-phase ultrasonic vibration generators and Light Emitting Diode (LED) devices. The ring-shaped two-phase ultrasonic vibration generators have a center hole. Each of the LED devices is provided in the center hole of the each two-phase ultrasonic vibration generator. The two-phase ultrasonic vibration generators includes a ring-shaped vibration stator configured to have a center hole; a first electrode layer provided under the vibration stator; a second electrode layer provided under the first electrode layer; and a piezoelectric ceramic group layer configured to include a first piezoelectric ceramic group for generating an A phase and a second piezoelectric ceramic group for generating a B phase. Growth plates are stimulated using two-phase ultrasound projected from the two-phase ultrasonic vibration generators and light projected from the LED devices.03-10-2011
20090171251ULTRASOUND TREATMENT OF ADIPOSE TISSUE WITH VACUUM FEATURE - There is provided herein, an apparatus for lysing of adipose tissue comprising a transducer adapted to transmit ultrasound to a target area tissue of a subject body; and a vacuum system adapted to suck a surface of the target area tissue into the transducer to facilitate acoustic contact between the surface of the target area tissue and the transducer.07-02-2009
20100016762SYSTEM AND METHOD FOR DELIVERING ENERGY TO TISSUE - An ablation system for treating atrial fibrillation in a patient comprises an elongate shaft having proximal and distal ends, a lumen therebetween and a housing adjacent the distal end of the elongate shaft. An energy source is coupled to the housing and is adapted to deliver energy to a target tissue so as to create a zone of ablation in the target tissue that blocks abnormal electrical activity thereby reducing or eliminating the atrial fibrillation in the patient. A sensor is adjacent the energy source and adapted to detect relative position of the energy source to the target tissue or characteristics of the target tissue. The system also has a reflecting element operably coupled with the energy source and adapted to redirect energy emitted from the energy source in a desired direction or pattern.01-21-2010
20100016763INTRALUMINAL FLUID PROPERTY STATUS SENSING SYSTEM AND METHOD - Implementations of an intraluminal fluid property status sensing system and method locate an acoustic transducer within a lumen of a biological creature to transmit ultrasound through intraluminal fluid to be reflected or otherwise affected by the fluid with subsequent reception by the same transducer. Reflection or interaction of the ultrasound with an intraluminal fluid depends upon one or more properties of the intraluminal fluid so can be used to determine status of such properties.01-21-2010
20120197164ULTRASOUND COUPLANT - The invention relates to the field of absorbent, self-coalescing materials, in particular hydratable polymeric materials, such as cartboxyrmethylchitosan, for use as ultrasound couplants.08-02-2012
20100152626ULTRASONIC TREATMENT OF GLAUCOMA - A method of treating glaucoma is described herein. The method includes the steps of providing an ultrasonic device that emits ultrasonic energy, holding the ultrasonic device at a location external to the trabecular meshwork, transmitting the ultrasonic energy at a frequency to a desired location for a predetermined time, causing biochemical changes to be initiated within the eye that may include triggering a presumed integrin response that initiates biochemical changes typified by but not limited to cytokines, enzymes, macrophage activity and heat shock proteins, and dislodging material built up in the trabecular meshwork.06-17-2010
20100241034ANALYSIS OF REAL TIME BACKSCATTER DATA FOR FAULT SIGNAL GENERATION IN A MEDICAL HIFU DEVICE - A method and system for checking functionality of an ultrasound therapy head. The waveform profile for typical ultrasound reflections for a functional therapy head are stored, and before use of a therapy head, an ultrasound energy burst (09-23-2010
20100228162Apparatus and Method for Tissue Ablation with Near-Field Cooling - A tissue ablation system facilitates lesioning deep tissue while preventing damage to superficial tissue and includes a probe having a distal end portion, at least one transducer carried on the distal end portion, and at least one acoustically transparent heat removal element thermally coupled to a target tissue within the beam path of the transducer. The transducer delivers acoustic energy to the tissue through the heat removal element in order to ablate the tissue; the heat removal element removes sufficient thermal energy from the tissue volume to prevent thermal necrosis in superficial tissue. The heat removal element may be a heat sink or a convective element. An optional temperature sensor provides advisory data to a practitioner and/or is coupled to a feedback control system operable to control delivery of acoustic energy to the tissue and/or a rate of thermal energy removal therefrom.09-09-2010
20100241035SYSTEM AND METHOD FOR ULTRA-HIGH FREQUENCY ULTRASOUND TREATMENT - A non-invasive ultra-high frequency ultrasound treatment method and system are provided. An exemplary method and system comprise a high-frequency ultrasound transducer system configured for providing ultrasound treatment to a patient such that the superficial and/or subcutaneous regions of the patient can be treated. An exemplary high-frequency ultrasound transducer system comprises a control system and a transducer configured to provide treatment to the superficial and/or subcutaneous regions of interest. The high-frequency ultrasound transducer may be configured to operate at higher frequencies and controlled power levels to provide treatment to the superficial and/or subcutaneous regions of interest. For example, higher frequencies within the range from approximately 20 MHz to 500 MHz or more may be utilized.09-23-2010
20090076420METHOD AND DEVICE FOR ADIPOSE TISSUE TREATMENT - A system and method for treatment of adipose tissue. One or more shock waves are generated focused on a region of adipose tissue located between 0.2 and 3 cm below the skin surface.03-19-2009
20110112445Handpiece for Ultrasound Treatments of Human Tissue - A handpiece (05-12-2011
20110112444ADVANCED HANDABLE SKIN CARE DEVICE AND OPERATING METHOD THEREOF - An apparatus for maintaining and supplying stable power to a skin care device comprising a DC-DC converting unit (05-12-2011
20100137751ULTRASONIC OPERATION APPARATUS - An ultrasonic surgical instrument that comprises a handpiece configured to treat living tissue with at least one of an ultrasonic vibration and a high-frequency current, a first generation unit configured to generate a drive current for producing the ultrasonic vibration, a second generation unit configured to generate the high-frequency current, a suction device configured to draw mist produced at the living tissue when the handpiece treats the living tissue with the ultrasonic vibration, and a control unit configured to control the suction device, causing the section device to draw the mist when outputs of both the first generation unit and the second generation unit are detected or when only the output of the first generation unit is detected. The apparatus further comprises a suction tube connected to the suction device, a suction path communicating with the suction tube, and a suction port made in the suction path.06-03-2010
20100222714HAND ACTIVATED ULTRASONIC INSTRUMENT - An ultrasonic surgical clamp coagulator apparatus is configured to effect cutting, coagulation, and clamping of tissue by cooperation of a clamping mechanism of the apparatus with an associated ultrasonic end-effector. The handle of the apparatus is configured to permit hand activation for cutting, coagulation, and clamping of tissue during surgical procedures. In order to promote convenient and efficient use of the apparatus, the fingertip controls are provided directly into the disposal shears handle in a position that allows surgeons to activate the device without repositioning their hand. The two buttons provide independent control of the two power levels available from the generator, matching the two foot pedal configuration of the prior art.09-02-2010
20100222715Methods and apparatus for intracranial ultrasound delivery - A method for delivering ultrasound energy to a patient's intracranial space involves forming at least one hole in the patient's skull, advancing at least one ultrasound delivery device at least partway through the hole(s), and transmitting ultrasound energy from the ultrasound delivery device(s). According to various embodiments, ultrasound delivery devices may be advanced into the epidural space, one or both ventricles and/or an intracerebral space of the patient's brain. In alternative embodiments, one or multiple holes may be formed in the skull, and any number of ultrasound delivery devices may be used. Intracranial ultrasound delivery may be used in diagnostic or therapeutic treatment of ischemic stroke, head trauma, atherosclerosis, perfusion disorders and other acute or chronic neurological conditions.09-02-2010
20100222713TISSUE PAD FOR USE WITH AN ULTRASONIC SURGICAL INSTRUMENT - An ultrasonic clamp coagulator assembly that is configured to permit selective cutting, coagulation and clamping of tissue during surgical procedures. An elongated portion of the instrument can be configured for endoscopic applications and has an outside diameter of less than 6 mm. The construction includes a clamping mechanism, including a clamp arm pivotally mounted at the distal portion of the instrument, which is specifically configured to create a desired level of tissue clamping forces, exceeding 4 pounds when the trigger is fully closed. The clamping mechanism includes a two-piece pad design and pad material that enables the higher tissue clamping forces and a force-limiting mechanism that effectively smooths out abusive tissue forces. The assembly also features hand activation configured to provide an ergonomical grip and operation for the surgeon. Hand switches are placed in the range of the natural swing of the surgeon's thumb, whether gripping the surgical instrument right-handed or left handed.09-02-2010
20130218054SEPARATION DEVICE FOR ULTRASOUND ELEMENT - There is provided in accordance with an exemplary embodiment of the invention a method and for keeping an ultrasound emission element away from a wall of a blood vessel or cavity comprising: inserting a catheter comprising the ultrasound emission element into a blood vessel or body cavity such that the ultrasound emission element is prevented from contacting a wall of the blood vessel or the cavity. There is also provided in accordance with an exemplary embodiment of the invention a device for keeping an ultrasound emission element away from a wall of a blood vessel or lumen.08-22-2013
20110028867APPARATUS AND METHOD FOR NON-INVASIVE DELIVERY AND TRACKING OF FOCUSED ULTRASOUND GENERATED FROM TRANSDUCER - The present invention provides an apparatus for non-invasive delivery of focused ultrasound to a targeted area of a biological tissue, and a method thereof. The apparatus comprises an ultrasound wave generator to provide an amplified modulated waveform, a resonance circuit for tuning the waveform to have a predetermined frequency, an ultrasound transducer for generating a focused beam of the tuned waveform, an applicator supporting the ultrasound transducer, and an ultrasound-tissue coupling bag detachably mounted to the ultrasound transducer.02-03-2011
20120143099SYSTEMS AND METHODS FOR IMPAIRING SMOOTH MUSCLE TISSUE FUNCTION - Systems and methods for impairing smooth muscle tissue function using energy and/or pressure are described herein. The systems and/or methods may be used in some embodiments to target smooth muscle tissue in the bronchial passages.06-07-2012
20120143097TREATMENT OF ATRIAL FIBRILLATION USING HIGH-FREQUENCY PACING AND ABLATION OF RENAL NERVES - A method for the treatment of a patient for the purpose of lowering blood pressure and/or treating cardiac arrhythmias, particularly atrial fibrillation includes the insertion of an ablation catheter into the lumen of a renal artery. The ablation catheter is equipped with an electrode that can stimulate the wall tissue in the renal artery to help identify the location of a renal nerve. High-frequency stimulation of the renal nerve causes a decrease in the blood pressure of the patient thereby indicating that a renal nerve is nearby. The ablation catheter is used to ablate the renal nerve using radiofrequency, ultrasound, microwave energy or cryogenic cooling. An irrigated ablation catheter may be used to decrease damage to cells in the wall of the lumen of the renal artery other than the renal nerve, such as the endothelial cells.06-07-2012
20100081970Apparatus for improving health - An apparatus for improving health includes a therapeutic assembly comprising a control panel, a horizontal central channel, a hollow cylinder rotatably disposed in the channel, a sound reproducing device, a light source adapted to emit colorful light rays, a pulsed low frequency generating unit adapted to generate magnetic resonance, an IR generator, a nano lamp, and an electromagnetic wave generating unit; and a table having a top magnetic massaging bed adapted to move lengthwise with respect to the table to dispose in the cylinder, the magnetic massaging bed being adapted to generate static magnetic fields.04-01-2010
20090177122Methods for treating inflammatory skin disorders - The invention provides methods for treating inflammatory skin disorders by administering low frequency ultrasound energy to decrease the inflammatory response. Exemplary skin disorders that can be treated include acne, rosacea, psoriasis, atopic dermatitis, seborrheic dermatitis, and contact dermatitis.07-09-2009
20110130688BONE INSPECTING SYSTEM, AND LOWER LEG SUPPORTING DEVICE - Provided is a bone inspecting system for placing the lower legs (L) of an examinee (P) on a proximal support block (06-02-2011
20080269647Device for Directing Ultrasound at a Target Region in a Human or Animal Body - The invention relates to a device for directing ultrasound at a target region in a human or animal body, in particular for treating proliferative tissue, comprising imaging means for generating one or more images of the target region in the body that is to be treated; processing means for processing the obtained images; at least one ultrasound transducer arranged for placement in direct proximity of the target region to be treated; and driving means for driving said at least one ultrasound transducer on the basis of signals generated by the processing means. The object of the invention is to provide a device as referred to in the introduction that enables a more precise orientation of the ultrasound transducer relative to the target region. According to the invention, the device is to that end provided with positioning means for orienting the ultrasound transducer in the three-dimensional space relative to the target region.10-30-2008
20090105617Non-invasive quantitative body contouring by high intensive focused ultrasound - An apparatus is invented for breaking adipose tissue involving delivering ultrasonic energy at a multiplicity of target layers of volume under the skin. The delivered ultrasound is focused on the target layers. One or a plurality of ultrasonic focuses scan the target layers. The scanning ultrasonic focuses break the adipose tissue quantitatively, while other non-adipose tissues are generally not broken. The quantitative breaking process of adipose tissue is performed by quantitative feedback information. Another ultrasound of different frequency helps to move the broken adipose tissue away from the targeted volumes in body circulation. An ultrasound transducer assembly has at least one transducer array of high intensity focused ultrasound (HIFU) and at least one transducer of high intensity unfocused ultrasound.04-23-2009
20100204617Ultrasonic probe with acoustic output sensing - An ultrasonic probe comprising a source adapted to output ultrasonic energy, and an acoustic output sensor adapted to sense at least a portion of the ultrasonic energy. The ultrasonic probe may be, for example, part of an ultrasound system further comprising a controller, wherein the acoustic output sensor may be adapted to transmit a signal in response to sensed ultrasonic energy.08-12-2010
20110112446ULTRASONIC TREATMENT APPARATUS AND ULTRASONIC TREATMENT METHOD - Provided is an ultrasonic treatment apparatus which includes a drive signal generating unit (such as a FPGA circuit), a detecting unit (output detecting circuit), a range setting unit (condition setting circuit), and a frequency controller (frequency changing circuit). The drive signal generating unit generates a drive signal of a predetermined oscillating frequency by performing a frequency sweep. The detecting unit detects information on a state of the drive signal. The range setting unit sets a range of frequency sweep based on identification information of an ultrasonic transducer. The frequency controller performs a frequency control in the range of frequency sweep based on the information on the state of the drive signal.05-12-2011
20100312150SYSTEM AND METHOD FOR MEDICAL TREATMENT USING ULTRASOUND - A system and method for medical treatment of tissue using ultrasound. The system comprises a probe having an array of transducer elements, an ultrasound waveform generator adapted to generate at least one electrical ultrasound signal, and a plurality of phase controls, each coupled to the ultrasound waveform generator and adapted to generate from the electrical ultrasound signal a phase-shifted drive signal that is coupled to an associated transducer element. The drive signal is effective to control grating lobe foci emitted by the array. The method employs the system.12-09-2010
20130138017ULTRASOUND GUIDED AUTOMATED WIRELESS DISTRACTION OSTEOGENESIS - A bone distraction device applies guided incremental forces to opposing bone segments for the purpose of generating native bone in an osteotomy site (distraction osteogenesis). The bone distraction device automatically adjusts the rate of the distraction utilizing feedback received from the ultrasound transducer and other sensors, using an adaptive decision algorithm(s). A wireless transmitter allows for remote guidance, feedback and monitoring.05-30-2013
20130138018NERVE TREATMENT SYSTEM - A method of treatment includes delivering an agent into a patient, and providing energy inside the patient so that the energy can interact with the agent to treat a nerve. A system for treatment includes a source of agent for delivery into a patient, and an energy source for providing energy inside the patient so that the energy can interact with the agent to treat a nerve.05-30-2013
20130144192ULTRASOUND NEUROMODULATION TREATMENT OF ANXIETY (INCLUDING PANIC ATTACKS) AND OBSESSIVE-COMPULSIVE DISORDER - Disclosed are methods and systems and methods for non-invasive neuromodulation using ultrasound to treat anxiety (including panic attacks) and Obsessive-Compulsive Disorder. The neuromodulation can produce acute or long-term effects. The latter occur through Long-Term Depression (LTD) and Long-Term Potentiation (LTP) via training. Included is control of direction of the energy emission, intensity, frequency, pulse duration, and phase/intensity relationships to targeting and accomplishing up regulation and/or down regulation.06-06-2013
20130144193HYDROGEL ULTRASOUND COUPLING DEVICE - The present invention relates to an ultrasound coupling device that includes a gel component and a coupling compartment. The present invention also relates to various kits and methods for using the ultrasound coupling device with low-intensity ultrasound transducers and therapy. The present invention also relates to methods of making the ultrasound coupling device of the present invention. The present invention further relates to an array that includes a plurality of ultrasound coupling devices of the present invention, and methods of using the array.06-06-2013
20100331742SURGICAL OPERATING APPARATUS - A surgical operating apparatus includes a probe for outputting energy for performing therapeutic treatment of a living body, a jaw which is openable/closable relative to the probe, and an output mode switching section which selectively switches, in accordance with an open/closed state of the jaw, an output of the surgical operating apparatus between a bipolar mode in which the probe and the jaw are used as high-frequency electrodes, and a probe-only output mode in which the energy is output from only the probe.12-30-2010
20110213279APPARATUS AND METHOD FOR SELECTIVE ULTRASONIC DAMAGE OF ADIPOCYTES - An apparatus and a method for treating adipose tissue located beneath a patient's skin is disclosed herein. In some embodiments, the apparatus includes a sonotrode 140 and an ultrasound transducer 130 operative to induce longitudinal and/or transversal ultrasound vibrations in a least a portion of the sonotrode 140. In some embodiments, the apparatus provides a “cold” or “transverse” mode where ultrasound energy delivered to the patient is primarily energy of transverse ultrasound waves, and a “hot” or “longitudinal” mode where ultrasound energy delivered to the patient is primarily energy of longitudinal ultrasound waves. The longitudinal waves may be useful for ‘pre-heating’ tissue of the patient before delivering the transverse waves.09-01-2011
20110028866Ultrasound Apparatus for Creating and Delivering Therapeutic Solutions - The present invention relates to an ultrasound device and method for treating a wound by creating a therapeutic combination of materials with ultrasonic waves and delivering that combination into the wound bed. The apparatus comprises a horn having an internal chamber including a back wall, a front wall, and at least one side wall, a radiation surface at the horn's distal end, at least one channel opening into the chamber. Within the internal chamber of the horn the healing factor to be delivered to the wound is mixed with a suitable carrying agent to create a therapeutic solution. Affixed to the distal end of the horn is a cavitation chamber capable of deforming downwards that receives the therapeutic solution. The downward deformation of the cavitation chamber applies pressure to the therapeutic solution contained within the chamber pushing the solution into the wound bed.02-03-2011
20110040214IMAGE GUIDED HIGH INTENSITY FOCUSED ULTRASOUND TREATMENT OF NERVES - A method for using high intensity focused ultrasound (HIFU) to treat neurological structures to achieve a desired therapeutic effect. Depending on the dosage of HIFU applied, it can have a reversible or irreversible effect on neural structures. For example, a relatively high dose of HIFU can be used to permanently block nerve function, to provide a non-invasive alternative to severing a nerve to treat severe spasticity. Relatively lower doses of HIFU can be used to reversibly block nerve function, to alleviate pain, to achieve an anesthetic effect, or to achieve a cosmetic effect. Where sensory nerves are not necessary for voluntary function, but are involved in pain associated with tumors or bone cancer, HIFU can be used to non-invasively destroy such sensory nerves to alleviate pain without drugs. Preferably, ultrasound imaging synchronized to the HIFU therapy is used to provide real-time ultrasound image guided HIFU therapy of neural structures.02-17-2011
20110040213Ultrasonic Surgical Apparatus with Silicon Waveguide - Ultrasound surgical apparatus are disclosed, including: medical ultrasound handpieces with proximally mounted ultrasound radiators configured to create a distally-focused beam of ultrasound energy, in combination with distal guide members for control of focal point depth; medical ultrasound handpieces with proximally mounted ultrasound radiators configured to create a distally-focused beam of ultrasound energy, in combination with distal rolling members for manipulability and control of focal point depth; medical ultrasound handpiece assemblies with coupled end effectors providing a probe with a probe dilation region configured to have an average outside diameter that is equal to or greater than the average outside diameter of a probe tip and neck; as well as junctions to an ultrasonically inactive probe sheath; medical ultrasound handpiece assemblies with coupled end effectors having positionable, ultrasonically inactive probe sheath ends slidably operable to both cover and expose at least a probe tip; and ultrasound transducer cores including a transducing structure affixed to a longitudinally elongated, generally planar, single crystal or polycrystalline material waveguide.02-17-2011
20110245734TREATMENT METHODS - The invention generally relates to methods for treating osteoarthritis. In certain embodiments, methods of the invention involve providing stimulation to a subject's central nervous system to modulate a signal sent to or from the subject's joint, thereby treating osteoarthritis.10-06-2011
20110213280DISPOSABLE TRANSDUCER SEAL - A transducer seal designed to seal an open aperture of a transducer housing for a therapeutic ultrasound procedure. The seal has a membrane, a retainer and a mating device for locking in place with the transducer housing. The membrane is essentially transparent to ultrasound energy while being stretched taut about the retainer. The transducer seal may be made in a disposable or re-usable form.09-01-2011
20090088668SURGICAL OPERATING APPARATUS - A surgical operating apparatus includes a sheath having a distal end and a proximal end, a rod-shaped probe main body which is inserted into the sheath and has a distal end and a proximal end, and which is transmitted with ultrasonic vibration, a jaw pivoted to the distal end of the sheath, a probe distal end which is provided at the distal end of the probe main body and meshes with the jaw, and a driving member which is provided with a tubular main body portion which is inserted into the sheath slidably along an axial direction of the sheath and an acting portion which is provided at a distal end of the main body portion and has a connection portion connected to the jaw, for rotating the jaw according to a sliding action of the main body portion, wherein the sheath includes a notched portion for preventing the sheath from contacting the driving member when the connection portion of the driving member with the jaw moves in a direction perpendicular to a sliding direction of the driving member at a rotation time of the jaw.04-02-2009
20100217160Ultrasonic Wave Radiator for Treatment - An ultrasonic wave radiator suitable for a cerebral infarction therapy apparatus that is attached to indeterminate curvilinear surface of the scalp of a patient under therapy and dissolves thrombus inside a cerebral blood vessel by outputting ultrasonic vibrations of a plurality of frequencies or an ultrasonic vibration having a wide frequency band. The ultrasonic transducer 08-26-2010
20100217161Delivery of therapeutic focused energy - A system for delivering ultrasonic focused energy, the system comprising a transducer unit for delivering the ultrasonic focused energy, the transducer unit comprising an interface medium adapted to contact at least a portion of a treatment region in a treatment area, and further comprising an electromagnetic (EM) radiating element adapted to transmit EM radiation towards the interface medium, wherein a reflection of the EM radiation from the interface medium is indicative of an extent of acoustic contact; and an energy processing unit adapted to send electrical energy to the transducer unit.08-26-2010
20090048544Apparatus and method for ultrasound treatment - Apparatus for generating high intensity acoustic beams, the apparatus comprising: a piezoelectric transducer characterized by a plurality of harmonic resonant frequencies of vibration; and at least one driving circuit connected to the transducer that is controllable to excite at least two vibrations of the transducer at different harmonic vibration frequencies of the vibrator, which vibrations generate a high intensity acoustic beam for each of the harmonic frequencies.02-19-2009
20090036802Swing Type High-Intensity Focused Ultrasound Therapeutic Apparatus and Mri Guided High-Intensity Focused Ultrasound Therapeutic System Having Such a Swing Type Apparatus - The present invention belongs to the technical field of ultrasound therapy, and relates to a swing type high-intensity focused ultrasound therapeutic apparatus and an MRI guided high-intensity focused ultrasound therapeutic system having such a swing type apparatus. The swing type high-intensity focused ultrasound therapeutic apparatus comprises an ultrasound transducer and a moving-locating mechanism thereof, wherein said moving-locating mechanism adopts a swing mechanism which is connected to the ultrasound transducer by a supporting rod. The MRI guided therapeutic system comprises this swing type therapeutic apparatus. In the present invention, the ultrasound transducer moves freely in multiple dimensions and the moving-locating mechanism adopts a swing mechanism, so the interference generated by the MRI guided high-intensity focused ultrasound therapeutic system on the MRI apparatus is quite small and thereby the quality of the ultrasound image obtained is good.02-05-2009
20100056962Acoustic Beam Forming in Phased Arrays Including Large Numbers of Transducer Elements - A focused ultrasound system includes a transducer array, a controller for providing drive signals to the transducer array, and a switch. The transducer array includes a plurality of “n” transducer elements, and the controller includes a plurality of “m” output channels providing sets of drive signals having respective phase shift values, “m” being less than “n.” The switch is coupled to the output channels of the controller and to the transducer elements, and is configured for connecting the output channels to respective transducer elements. The controller may assign the transducer elements to respective output channels based upon a size and/or shape of a desired focal zone within the target region, to steer or otherwise move a location of the focal zone, and/or to compensate for tissue aberrations caused by tissue between the transducer array and the focal zone, geometric tolerances and/or impedance variations of the transducer elements.03-04-2010
20110152728Event Driven Configuration of a Surgical System Console - The present disclosure is directed to a user interface for modifying preprogrammed relationships between a plurality of subsystems of a surgical system. The user interface may be presented on a system display screen. It includes one or more selectable triggering events shown on the display screen, with each of the one or more selectable triggering events identifying a subsystem condition that selectively occurs during a surgical procedure performed with the surgical system. The interface also includes a plurality of selectable responses to the one or more selectable triggering events. The selectable responses deviate from the preprogrammed relationships between subsystems of the surgical system.06-23-2011
20090216158ULTRASOUND AND TISSUE REPAIR - Methods of using an ultrasound signal to promote tissue repair by causing cells to form focal adhesions without the involvement of syndecans, in particular syndecan-1, syndecan-4 or PKCα are disclosed.08-27-2009
20090216157ULTRASONIC OPERATING APPARATUS - An ultrasonic treatment instrument is provided with an ultrasonic transducer, a probe portion to which ultrasonic wave outputted from the ultrasonic transducer is transmitted, a sheath portion into which the probe portion is inserted detachably, the sheath portion including at a distal end portion thereof, a grasping member rotatably supported so as to face the probe portion, and a handle portion coupled to a proximal end portion of the sheath portion detachably and operating the grasping member such that the grasping member is opened and closed to the probe portion, where the distal end portion of the probe portion includes a cavitation production portion where the distal end portion of the probe portion has, on a face thereof facing the grasping member, a flat face extending so as to intersect a vibration direction of the ultrasonic vibration, and cavitation is produced by the flat face in a state that a body tissue has been grasped between the grasping member and the distal end portion of the probe portion.08-27-2009
20110251527OPERATION OF PATTERNED ULTRASONIC TRANSDUCERS - A method for lysing fat cells using a multi-element, phased array piezoelectric transducer, the method comprising: providing a multi-element, phased array piezoelectric transducer comprising a single unitary piece of piezoelectric material having a plurality of electrode elements being formed as a segmented conductive layer on at least one surface of the piezoelectric material, each segment of the conductive layer being associated with an individual transducer element; positioning the transducer over a body of a patient, in proximity to a target volume containing fat cells; causing at least some of the transducer elements to emit ultrasound energy by exciting their associated electrode elements with high frequency voltages, the ultrasound energy having a power density at the target volume which is higher than a cavitation threshold; and spatially steering the ultrasound energy across the target volume by controlling the excitation of electrode elements in the time domain, thereby inducing cavitation in fat cells contained in the target volume.10-13-2011
20110251526MULTI-FUNCTIONAL COSMETIC DEVICE USING ULTRASONIC WAVE - Disclosed is a multi-functional cosmetic device using ultrasonic wave which the user can freely use at any pose and that can provide sufficient cosmetic effects by uniformly spraying mist of beauty water/medicine solution to the face. —For this, the multi-functional cosmetic device using ultrasonic wave according to the present invention provides a fine through hole on the upper surface of the nozzle portion in order to keep the solution ejecting out of the vessel and spraying mist of the water/medicine solution even when the device is used upside down so that the user can use the cosmetic device freely at any pose. Also, a mesh having fine pores are installed on the upper portion of the nozzle, a wave spring is installed on the upper surface of the mesh to prevent leaking of liquids from the end of the nozzle by maintaining constant pressure of mesh against the nozzle. By using the multi-functional cosmetic device using ultrasonic wave according to the present invention, the user can use the cosmetic device freely at any pose since a fine through hole is formed on the upper surface of the nozzle portion in order to keep the solution ejecting out of the vessel and spraying mist of the water/medicine solution even when the device is used upside down.10-13-2011
20110098609TISSUE TEMPERATURE INDICATING ELEMENT FOR ULTRASOUND THERAPY - The present invention relates to a hydrogel-containing temperature indicating element for use in ultrasound therapy. The temperature indicating element of the present invention and the therapeutic device and method making use of the same enable in some embodiments an automated adaptation of the power output as a function of the tissue temperature, avoiding therefore overheating or burning of the skin.04-28-2011
20110077557MEDICAL ULTRASOUND DEVICE WITH LIQUID DISPENSING DEVICE COUPLED TO A THERAPY HEAD - A medical ultrasound system. A base unit is included having system electronics, a user interface and ultrasound control electronics. An ultrasound therapy head is in electronic communication with the base unit. The therapy head includes a replaceable, sealed transducer cartridge with a coupling fluid therein. A cooling system is provided for cooling the coupling fluid. A plurality of guide indicators are positioned around the therapy head to align with crossed lines on a patient so as to properly align the therapy head prior to use. The therapy head can provide variable treatments to an area while the therapy head is in contact with a patient.03-31-2011
20110105961METHODS, COMPOSITIONS AND APPARATUSES FOR FACILITATING REGENERATION - Apparatuses, compositions and methods for removing cells which interfere with regenerative processes. The apparatuses, compositions and methods selectively kill partially functional and/or non-functional cells versus functional cells while protecting functional proliferative cells to the extent that, upon removal of the killed cells by disintegration or scavenging, functional cells replace the partially- or non-functional cells.05-05-2011
20110077559ULTRASOUND THERAPY HEAD WITH MOVEMENT CONTROL - A therapy head for use in HIFU procedures is described. The therapy head has an enclosure with a window, an energy applicator and a means of moving the energy applicator within the enclosure. The therapy head uses motors and actuators to move the energy applicator, usually an ultrasound transducer, inside the enclosure. A controller is provided either internally or externally that allows the therapy head to identify and distinguish locations where the therapy head should be to radiate energy into a patient. The controller uses the motors and actuators to move the energy applicator into the desired locations.03-31-2011
20110077555TRANSDUCER CARTRIDGE FOR AN ULTRASOUND THERAPY HEAD - A medical ultrasound system. A base unit is included having system electronics, a user interface and ultrasound control electronics. An ultrasound therapy head is in electronic communication with the base unit. The therapy head includes a replaceable, sealed transducer cartridge with a coupling fluid therein. A cooling system is provided for cooling the coupling fluid. A plurality of guide indicators are positioned around the therapy head to align with crossed lines on a patient so as to properly align the therapy head prior to use. The therapy head can provide variable treatments to an area while the therapy head is in contact with a patient.03-31-2011
20110077556CARTRIDGE FOR USE WITH AN ULTRASOUND THERAPY HEAD - A medical ultrasound system. A base unit is included having system electronics, a user interface and ultrasound control electronics. An ultrasound therapy head is in electronic communication with the base unit. The therapy head includes a replaceable, sealed transducer cartridge with a coupling fluid therein. A cooling system is provided for cooling the coupling fluid. A plurality of guide indicators are positioned around the therapy head to align with crossed lines on a patient so as to properly align the therapy head prior to use. The therapy head can provide variable treatments to an area while the therapy head is in contact with a patient.03-31-2011
20110071440INTERVENTIONAL CATHETERS INCORPORATING ASPIRATION AND/OR INFUSION SYSTEMS - An interventional catheter assembly comprising a catheter for insertion and guidance to a target site in a body lumen or a cavity and an operating head mounted in proximity to a distal end of the catheter and comprising a system for removing obstructive material from the target site is provided. In certain embodiments, the catheter assembly includes at least one aspiration port located proximal to the operating head that communicates with a first sealed lumen for withdrawing fluids and obstructive material from the target site, together with at least one liquid infusion port penetrating the catheter and located proximal to the at least one aspiration port that communicates with a second sealed lumen for supplying fluid to a location in proximity to the target site.03-24-2011
20110251525SYSTEMS AND METHODS FOR TREATING LUNG TISSUE - A system for treating lung tissue includes a tube having a distal end, an anchoring device secured to the tube, the anchoring device configured to anchor at least a portion of the tube against an esophagus, a trachea, or a bronchus; and an ablation device carried within a lumen of the tube.10-13-2011
20120302927METHODS FOR CHARACTERIZING NONLINEAR FIELDS OF A HIGH-INTENSITY FOCUSED ULTRASOUND SOURCE AND ASSOCIATED SYSTEMS AND DEVICES - The present technology is directed to methods for characterizing nonlinear ultrasound fields and associated systems and devices. In several embodiments, for example, a method of calculating output of a high intensity focused ultrasound (HIFU) device comprises treating a target site with a multi-element HIFU array. In some embodiments, the array comprises a generally spherical segment. The method can further include simulating a field of the array by setting a boundary condition for the array. The boundary condition can be set by simplifying at least one geometrical aspect of the generally spherical segment.11-29-2012
20090018473Methods and Apparatus for Testing Disruption of a Vagal Nerve - Method and apparatus for disrupting a gastric vagal nerve in the gastroesophageal region and testing the function and disruption of the vagal nerve. In one example embodiment, a treatment device applies ultrasound at a high energy level, such as high intensity focused ultrasound, to a vagal nerve to disrupt it and then ultrasound at a lower energy level to another portion of the vagal nerve, preferably further from the stomach, so as to stimulate the vagal nerve. Alternative ways to test the function or disruption of the vagal nerve involve using PCP-GABA, a pancreatic polypeptide, pressure changes inside the stomach, the gastric mucusol pH, a dye agent in the stomach, and other tests.01-15-2009
20090018472POWER PARAMETERS FOR ULTRASONIC CATHETER - In one embodiment of the present invention, a method of applying ultrasonic energy to a treatment site within a patient's vasculature comprises positioning an ultrasound radiating member at a treatment site within a patient's vasculature. The method further comprises activating the ultrasound radiating member to produce pulses of ultrasonic energy at a cycle period T≦1 second. The acoustic parameters such as peak power, pulse width, pulse repetition frequency and frequency or any combination of them can be varied non-linearly.01-15-2009
20120277639Flexi-PCB Mounting of Ultrasonic Transducers for Enhanced Dermal and Transdermal Applications - An ultrasound transducer patch (11-01-2012
20120203142Continuous Single Wire Steerable Catheter - A steerable catheter includes a body portion, a flexible catheter body with a proximal end and a distal tip and a continuous steering wire passing through the flexible body from the proximal end to the distal tip and turning back through the flexible body from the distal tip to the proximal end.08-09-2012
20100076351Ultrasonic Therapy System Reducing the Electromagnetic Interference to the Imaging Device - An ultrasonic therapy system capable of reducing the electromagnetic interference to the imaging device includes an imaging device, an ultrasonic therapy device and an electric controlling unit. The ultrasonic therapy device includes an ultrasonic therapy applicator and the movement positioning units thereof. Driving motors for controlling the movement of the ultrasonic therapy applicator are provided in the movement positioning units, wherein the driving motors are disposed outside the area where the electromagnetic wave of the driving motors can interfere with the imaging device, and the driving motors are connected to the ultrasonic therapy applicator through gearing units.03-25-2010
20130165823ULTRASONIC IRRADIATION DEVICE - An ultrasonic irradiation device includes a sound source, a holding member, a first support member and a second support member. The sound source is configured to be placed in a space at least a part of which is covered with a wall surface and emit an ultrasonic wave toward a target area. The holding member is configured to hold the sound source. The first support member is configured to push a first area of the wall surface so that a distance between the sound source and the target area is kept at a predetermined value, the first supporting member being disposed on the holding member. The second support member is configured to push a second area of the wall surface including an area other than the first area so that the sound source is fixed to the wall surface together with the first support member.06-27-2013
20110251524DEVICE FOR ULTRASOUND TREATMENT AND MONITORING TISSUE TREATMENT - Apparatus is provided, including first and second support structures for placement on skin of a subject. At least one of the first and second structures is moveable with respect to the other so as to draw a portion of the skin and underlying tissue of the subject between respective lateral surfaces of the support structures. At least one ultrasound transducer is moveably coupled to the first support structure along an axis of the structure that is not parallel to the lateral surface of the structure. The ultrasound transducer is configured to transmit toward the portion of skin and underlying tissue one or more forms of acoustic radiation energy, including treatment energy. At least one acoustic element is coupled to the second support structure. Other applications are also described.10-13-2011
20110251523SKIN CARE APPARATUS AND METHOD OF SKIN CARE USING THE SAME - The present invention's effective treatment is based on ultrasound, ion delivery and far infrared rays, the beneficial energy of the ions attack the bacteria of the skin and strengthens the capabilities of cellular resistance to increase skin elasticity, reduces visibility of pores and smoothes the skin, Far Infrared Rays improves the circulation of blood vessels and speeds skin metabolism, the ultrasound's micro massage feature strengthens the elasticity of the skin, rendering skin younger and more luminous.10-13-2011
20110178443SYSTEM AND METHODS FOR DESTROYING ADIPOSE TISSUE - Methods and systems for the destruction of adipose tissue are disclosed. A method is provided for creating a surface map corresponding to a volume of adipose tissue for noninvasive treatment, and additional methods are provided for the treatment of the adipose tissue.07-21-2011
20110178442PATIENT FEEDBACK FOR CONTROL OF ULTRASOUND DEEP-BRAIN NEUROMODULATION - Disclosed are methods and systems and methods for patient-feedback control of non-invasive deep brain or superficial neuromodulation using sound impacting one or multiple points in a neural circuit to produce acute effects and, with application in multiple sessions, Long-Term Potentiation (LTP) or Long-Term Depression (LTD) to treat indications such as neurologic and psychiatric conditions. One or more of sonic transducer positioning, intensity, frequency, dynamic sweeps, phase/intensity relationships, and firing patterns are changed through feedback from the patient to optimize patient experience through up-regulation or down regulation. Examples are decreases in acute pain or tremor due to more effective impact on the neural targets.07-21-2011
20110178441METHODS AND DEVICES FOR MODULATING CELLULAR ACTIVITY USING ULTRASOUND - The present invention comprises methods and devices for modulating the activity or activities of living cells, such as cells found in or derived from humans, animals, plants, insects, microorganisms and other organisms. Methods of the present invention comprise use of the application of ultrasound, such as low intensity, low frequency ultrasound, to living cells to affect the cells and modulate the cells' activities. Devices of the present invention comprise one or more components for generating ultrasound waves, such as ultrasonic emitters, transducers or piezoelectric transducers, composite transducers, CMUTs, and which may be provided as single or multiple transducers or in an array configurations. The ultrasound waves may be of any shape, and may be focused or unfocused.07-21-2011
20090005711Systems and methods for opening of the blood-brain barrier of a subject using ultrasound - A system and method for opening the blood-brain barrier in the brain of a subject is disclosed. In some embodiments, a region of the brain of a subject is targeted for opening; and a focused ultrasound beam is applied through the skull of the subject to the targeted region to open the blood-brain barrier in the brain of the subject.01-01-2009
20100100015ULTRASOUND SYSTEMS AND METHODS FOR TREATNG ISCHEMIC LIMBS OR TISSUE AFFECTED BY PERIPHERAL ARTERIAL DISEASE - A method of treating tissue within a body includes aiming an ultrasound transducer towards target tissue, and delivering ultrasound energy towards the target tissue to thereby reduce pain at the target tissue. A method of treating tissue within a body includes aiming an ultrasound transducer towards target tissue, and delivering ultrasound energy towards the target tissue to increase nitric oxide at the target tissue. An ultrasound system includes a first ultrasound transducer for emitting ultrasound energy from outside a patient, and drive circuitry coupled to the first ultrasound transducer, wherein the drive circuitry is configured to generate a drive signal at a frequency that is between 20 kHz and 100 kHz for the first ultrasound transducer.04-22-2010
20090318838Neoplastic cell destruction device and method utilizing low frequency sound waves to disrupt or displace cellular materials - A neoplasm cell destruction device utilizing low frequency sound waves to disrupt or displace cellular materials in neoplastic cells so as to damage and ultimately destruct the neoplastic cells. The device includes a plurality of signal generators, a controller, a plurality of amplifiers, a plurality of transducers, and a target interface. The controller is in electrical communication with, and generates timing and control signals for simultaneously activating, the plurality of signal generators. Each amplifier is in electrical communication with a respective signal generator and amplifies the signal generated by the respective signal generator so as to form an amplified signal. Each transducer is in electrical communication with a respective amplifier and is driven by the amplified signal formed by the respective amplifier. The target interface combines the waveforms formed by the plurality of transducers to form an interference wave that is a low frequency sound wave.12-24-2009
20090312673SYSTEM AND METHOD FOR DELIVERING ENERGY TO TISSUE - Methods and apparatus for treating a patient include an ablation device for treating atrial fibrillation. The device includes a housing having proximal and distal ends, and an energy source adjacent the distal end of the housing. The energy source has an active portion and an inactive portion. The active portion is adapted to deliver energy to tissue when the energy source is energized. This creates a partial or complete zone of ablation in the tissue that blocks abnormal electrical activity, thereby reducing or eliminating atrial fibrillation in the patient. The inactive portion does not emit energy or emits substantially no energy when the energy source is energized.12-17-2009
20120203141METHOD AND APPARATUS FOR REDUCING/SUPPRESSING PAIN IN DIGITS - A therapeutic device and method for blocking pain in a patient's digit includes a ring-like vibratory element adapted to be fitted about the digit temporarily and controller coupled to the ring-like vibratory element for controlling its operation. By applying vibration to the patient's digit, pain transmission is blocked or lessened along the digit, allowing the patient or a caregiver to provide treatment to the digit with reduced pain, such as when a diabetic's finger is to be stuck for drawing blood for a blood sugar measurement). Moreover, if the digit is injured, the present invention can provide pain relief from the injury as well. Further, the invention can be applied to the digit in combination with other pain-reducing therapies, such as the application of ice, the application of topical analgesics, the application of local anesthetics, etc. The controller includes an on/off control switch and a switch for controlling the vibratory frequency. The controller further includes a battery power source for powering the ring-like vibratory element. Also, the ring-like vibratory element includes an electrically-powered vibratory motor and/or a piezoelectric ultrasound transducer for creating vibrations in the digit. The vibratory element includes two vibratory parts, to be positioned on opposite sides of the digit, along the nerve bundles to maximize the blockage of pain.08-09-2012
20090259149POWER SUPPLY APPARATUS FOR OPERATION - A power supply apparatus for operation for outputting power to a surgical instrument includes a resonant frequency detection section for detecting a resonant frequency which minimizes the impedance of the surgical instrument, and an abnormality detection section for detecting whether or not a value of the resonant frequency or a variation amount of the resonant frequency per unit time exceeds a predetermined numerical range or a reference variation value. The predetermined numerical range or the reference variation value is set on the basis of a value and a variation amount of the resonant frequency corresponding to a temperature change of the surgical instrument. By detecting an abnormality in this manner, the surgical instrument can be prevented from being broken.10-15-2009
20090247911Multiple-angle switched high intensity focused ultrasound - A multiple-angle switched high intensity focused ultrasound device having at least two focused ultrasound transducers mounted in a frame so that the focal zones of all transducers intersect. Each of the transducers is independently driven from a radiofrequency (RF) generator. The RF driving signal is switched so that no more than one transducer is operated at a time. This allows shaping the temperature distribution in the target area by overlapping thermal contributions of each transducer.10-01-2009
20080275371Vibrator with a plurality of contact nodes for treatment of myocardial ischemia - A vibrator for use in enhancement of pre-hospital coronary thrombolysis comprising a vibration source operable to generate vibration at a frequency in the range of 1-1000 Hz with at least a pair of oscillatory contacts spaced to enable simultaneous seating to the anatomic left and right of the sternum (such as to match the geometry of the right and left coronary arteries) of a patient in need of coronary thrombolysis. The preferred vibrator is operable to emit vibration in the low frequency sonic range (at least 20 Hz) with an amplitude of about 1 mm-15 mm (and more preferably greater than 2 mm), such as to provide an effective transthoracic tool for acute coronary thrombolysis applications. In a variation, greater than a pair of contacts are utilized to provide oscillatory contact at differing intercostal space levels (in order to maximize vibratory penetration to the heart which is variably situated depending on the patient's anatomy).11-06-2008
20110264013APPARATUS AND METHOD FOR STIMULATION OF BIOLOGICAL TISSUE - An apparatus for generating focused currents in biological tissue is provided. The apparatus comprises an electric source capable of generating an electric field across a region of tissue and means for altering the permittivity of the tissue relative to the electric field, whereby a displacement current is generated. The means for altering the permittivity may be a chemical source, optical source, mechanical source, thermal source, or electromagnetic source.10-27-2011
20110264011MULTI-DIRECTIONAL DEFLECTABLE CATHETER APPARATUSES, SYSTEMS, AND METHODS FOR RENAL NEUROMODULATION - Multi-directional deflectable catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver a thermal element to a renal artery via an intravascular path. Thermally or electrical renal neuromodulation may be achieved via direct and/or via indirect application of thermal and/or electrical energy to heat or cool, or otherwise electrically modulate, neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers.10-27-2011
20110118633ULTRASONIC TREATMENT APPARATUS - An ultrasonic treatment apparatus, for radiation of ultrasonic waves onto a skin surface or inside the body of a person, serves to kill bacteria, viruses, etc. The apparatus includes a treatment vessel; a first ultrasonic generating element disposed at a predetermined location in the treatment vessel; and a vibrator unit movably disposed in the treatment vessel. The vibrator unit includes a housing forming a sealed chamber and serving as an abutment section to abut against a part to be treated, and a second ultrasonic generating element attached to the abutment section and having a hollow section formed on a rear face thereof. Not only a skin surface can be irradiated with ultrasonic waves by driving the first ultrasonic generating element, but also an interior part of the body can be irradiated with the ultrasonic waves by driving the second ultrasonic generating element.05-19-2011
20110118631TORQUE WRENCH AND ULTRASONIC SURGICAL DEVICE - A head portion includes an engaging portion capable of engaging with an engagement portion, a slit formed by cutting a part of a peripheral wall surface of the engaging portion, a protuberance which protrudes inward from the peripheral wall surface of the engaging portion, the protuberance including a slope the height of projection of which gradually increases along the circumference of the peripheral wall and which is oriented in a direction of rotation in a rotating operation, and a stop surface extending in radial directions of the engaging portion. The head portion includes an elastically deformable portion configured to cause at least one of two opposite side portions of the slit to be elastically deformed so that the slit is widened until a preset value is reached by the torque applied from the engaging portion to the engagement portion with the protuberance in mesh with an interlocking portion.05-19-2011
20100210976METHOD AND APPARATUS FOR TREATING TISSUES WITH HIFU - A method for treating a desired volume of tissue using HIFU or other energy modality to ablate a pattern of elemental treatment volumes each having a volume that is greater than that of the focal zone of the HIFU transducer but smaller than the overall volume of the desired treatment volume. In one embodiment, the pattern of elemental treatment volumes are arranged to form a shell which partially or wholly encapsulates the desired volume of tissue, which then necroses in situ due to effects other than direct HIFU damage (including some combination of ischemia, thermal conduction, inflammation, apoptosis, etc.). The necrosed tissue remains in the body and is subsequently resorbed and/or healed via normal body mechanisms.08-19-2010
20100022919Methods of Skin Grafting Using Ultrasound - The present invention provides improved methods for skin grafting using ultrasonic energy.01-28-2010
20110257561ENERGETIC MODULATION OF NERVES - A system for treatment of an autonomic nervous system of a patient includes a focused ultrasound energy source for placement outside the patient, wherein the focused ultrasound energy source is configured to deliver ultrasound energy towards a blood vessel with a surrounding nerve that is a part of the autonomic nervous system inside the patient, and wherein the focused ultrasound energy source is configured to deliver the ultrasound energy based on a position of an indwelling vascular catheter.10-20-2011
20090171249Ultrasound treatment of adipose tissue with vacuum feature - There is provided herein an apparatus for treatment of adipose tissue comprising a transducer for producing and directing acoustic waves at a surface of a subject body and a drawing element for drawing a surface of the subject body into the transducer.07-02-2009
20090171252THERAPY HEAD FOR USE WITH AN ULTRASOUND SYSTEM - Therapy heads and related medical systems having an actuation assembly for controlling the position/orientation of a directional energy applicator in at least two planes are disclosed. A therapy head includes an enclosure, a partition separating a lower compartment from an upper compartment, an aperture in the partition, a control arm extending through the aperture, an actuation assembly positioned within the upper compartment, and a directional energy applicator positioned in the lower compartment for transmitting energy through a window. The control arm includes an upper end disposed within the upper compartment and a lower end disposed within the lower compartment. The actuation assembly is coupled with the upper end of the control arm such that the control arm is movable by the actuation assembly in at least two planes. The directional energy applicator is coupled with the lower end of the control arm.07-02-2009
20090171250ULTRASOUND TREATMENT OF ADIPOSE TISSUE WITH FLUID INJECTION - There is provided herein, an apparatus for lysing of adipose tissue comprising a transducer adapted to transmit ultrasound to a target area tissue of a subject body and a fluid supplying element for automatically supplying a fluid to a contact area on a surface of the target area tissue of the subject body.07-02-2009
20090171248ULTRASOUND TREATMENT OF ADIPOSE TISSUE WITH FLUID INJECTION - There is provided herein an apparatus for treatment of adipose tissue comprising a transducer for producing and directing acoustic waves at a surface of a subject body and a dispenser element for supplying a fluid, through the transducer, to a contact area on the surface of a subject body.07-02-2009
20110077558ULTRASOUND ENDOSCOPIC SYSTEM - Embodiments of the invention include a device having an elongate section extending from a distal end to a proximal end, the elongate section may be configured to be inserted into a cavity of a body. The device may also include an end effector at the distal end of the elongate section. The end effector may have an end face. The end face may include a transducer configured to vibrate in response to an electric current. The elongate section may include a conduit configured to circulate coolant to the end effector.03-31-2011
20110152729VIBRATION GENERATING APPARATUS AND METHOD INTRODUCING HYPERSONIC EFFECT TO ACTIVATE FUNDAMENTAL BRAIN NETWORK AND HEIGHTEN AESTHETIC SENSIBILITY - Means is provided for generating a vibration or a vibration signal, which contains audible range components that are vibration components in the audible frequency range and super-highfrequency components within a range exceeding the audible frequency range up to a predetermined maximum frequency, and which has an autocorrelation order represented by at least either one of a first property and a second property. By applying the vibration or an actual vibration generated from the vibration signal to a human being, a fundamental brain activation effect for activating the fundamental brain network system constituted of a fundamental brain including the brain stem, thalamus and hypothalamus that are regions to bear the fundamental function of the human being and the fundamental brain network of neuronal projection from the fundamental brain to various brain regions is introduced.06-23-2011
20100191157Method for treating skin lesions - A method for treatment of skin lesions is provided using High Intensity Focused Ultrasound (HIFU). The method involves administering HIFU to a targeted skin lesion, wherein the application of the HIFU results in the removal of the targeted skin lesion and also results in the removal of skin lesions that are not directly targeted by the application of HIFU.07-29-2010
20110190669ULTRASONIC TRANSDUCER FOR A METALLIC CAVITY IMPLANTED MEDICAL DEVICE - Implantable medical devices including an ultrasonic transducer and methods of optimizing an ultrasonic transducer of an implantable medical device are disclosed. The implantable medical device can include a housing, an ultrasonic transducer disposed within an interior of the housing, and a limiting structure configured to constrain deformation of the ultrasonic transducer. The limiting structure can include a separate structure coupled to the housing, or can comprise a resonant portion of the housing itself. During operation, the ultrasonic transducer is configured to communicate at a frequency at or near a resonant frequency of the housing.08-04-2011
20110190668ULTRASOUND NEUROMODULATION OF THE SPHENOPALATINE GANGLION - Disclosed are methods and systems for non-invasive neuromodulation of the Sphenopalatine Ganglion and associated neural structures vidian nerve and/or sphenopalatine nerve using an ultrasound transducer to treat migraine and cluster headaches as well as other indications such as neurologic and psychiatric conditions. Treatment may be unilateral or bilateral.08-04-2011
20110201976LAPAROSCOPIC HIFU PROBE - A high-intensity focused ultrasound ablation of tissue using minimally invasive medical procedures is provided.08-18-2011
20110201975ULTRASOUND MEDICAL SYSTEM - An ultrasound medical system includes an ultrasound end effector and at least one non-ultrasound tissue-property-measuring sensor. The ultrasound end effector includes a medical ultrasound transducer assembly having at least one medical-treatment ultrasound transducer. The at-least-one non-ultrasound tissue-property-measuring sensor is supported by the ultrasound end effector and is positionable in contact with patient tissue.08-18-2011
20100022921ULTRASOUND PHASED ARRAYS - Ultrasound transducers are disclosed which focus acoustic energy at various focal locations while minimizing focal spot degradation and the generation of unwanted on-axis or off-axis energy concentrations through using a generally constant f-number at the various focal locations.01-28-2010
20100022920ULTRASOUND CATHETER AND METHODS FOR MAKING AND USING SAME - Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and, in some embodiments, a guidewire tube extending through the lumen. A distal head for disrupting occlusions is coupled with the distal end of the ultrasound transmission member and is positioned adjacent the distal end of the catheter body. Some embodiments include improved features such as a bend in the catheter body for enhancing positioning and/or advancement of the catheter.01-28-2010
20110218464System, Device and Methods of Tissue Treatment for Achieving Tissue Specific Effects - A tissue treatment system and a treatment applicator provide multi-modality treatment of skin, tissue and organ conditions and pathologies using different types of treatment energy, alone or in combination, including radiofrequency (RF) energy and ultrasound energy to achieve multiple and different treatment effects that are tissue-specific and tissue depth-specific. The system and the applicator according to the invention selectively and fractionally and, as an option, nonfractionally, treat one or more tissue zones within a three-dimensional volume of skin or other soft tissue with one or more energy types and precisely target measured treatment energy to specific tissue types, tissue layers and/or specific depths or locations within the volume of skin or tissue. The system and the applicator can also target one or more energy types to treat a specific location or depth within a given tissue layer. The system and the applicator can provide different RF and ultrasound treatment energies that accurately affect the structure or activity of different tissue types, layers and/or depths within a given tissue zone of the skin or tissue volume in accordance with the treatment effects desired in particular tissue layers and/or at particular tissue depths to thereby selectively produce multiple and different treatment impacts.09-08-2011
20100016765INTEGRATED SPECT IMAGING AND ULTRASOUND THERAPY SYSTEM - A method and apparatus for the integration of an ultrasound transducer with a SPECT imaging system is disclosed. The ultrasound transducer allows the delivery of particle-born drug therapies or thermally active therapies at the same site detected with SPECT imaging. The system includes a SPECT imaging subsystem; an ultrasound transducer for producing a signal representative of applied ultrasound and signally coupled to the SPECT imaging subsystem; and co-registering means for co-registering the signal representative of applied ultrasound in a coordinate system of SPECT imaging subsystem. The SPECT subsystem may be replaced with a SPECT/CT combined system to provide morphology that allows for treatment planning. In another embodiment, the ultrasound transducer can be used intermittently with the sequential gathering of SPECT images for tracking time-varying properties of the binding of specific SPECT contrast agents to biomarkers of disease. In this way, the ultrasound and SPECT imaging devices form a novel combination to improve patient care through improved spatial registration, therapy planning, and workflow.01-21-2010
20100016761APPLICATOR FOR SKIN TREATEMENT WITH AUTOMATIC REGULATION OF SKIN PROTRUSION MAGNITUDE - Described is an applicator for RF, ultrasound, and light skin treatment. The applicator allows a protrusion of skin to be formed within a cavity and maintained for a desired time, enables good coupling of the treatment energy with the skin and avoids negative pressure adversely affecting the skin.01-21-2010
20100280419Ultrasonically Assisted Fitness Method and Apparatus - A device for accelerating the loss of regional body fat tissue in an exercising person, which includes a plurality of ultrasonic transducers for emitting ultrasound, and an implement for containing the transducers which is positioned proximate to the regional body fat tissue in the exercising person. The device includes means for controlling the transducers, whereby said ultrasound enhances the loss of the regional body fat tissue in the exercising person when the device is positioned proximate the regional body fat tissue and ultrasound is admitted thereto.11-04-2010
20110118632CARDIAC ABLATION DEVICES - A cardiac ablation device treats atrial fibrillation by directing and focusing ultrasonic waves into a ring-like ablation region (A). The device desirably is steerable and can be moved between a normal disposition, in which the ablation region lies parallel to the wall of the heart for ablating a loop-like lesion, and a canted disposition, in which the ring-like focal region is tilted relative to the wall of the heart, to ablate only a short, substantially linear lesion. The ablation device desirably includes a balloon reflector structure (05-19-2011
20080287835Integrated Ultrasound Therapy Transducer Assembly - The present invention is to provide an integrated ultrasound therapy transducer. It includes a piezoelectric transducer to generate therapy ultrasound, a support to support the piezoelectric transducer, a power amplifying module to drive the piezoelectric transducer. Wherein both the power amplifying module and the piezoelectric transducer are installed within the enclosure of the therapy transducer. The advantages of the integrated ultrasound therapy transducer assembly of the present invention include minimizing ultrasound therapy equipment and to decrease its volume and weight; reducing the electromagnetic interference and radiation greatly; and realizing the consistent performances of the ultrasound therapy equipments in mass productions and making the ultrasound therapy equipments have interchangeability.11-20-2008
20130012839SYSTEM AND METHOD FOR TREATING A THERAPEUTIC SITE - A targeting catheter is used to locate an arteriotomy, such as is formed during a femoral artery catheterization procedure. The targeting catheter includes one or more targeting aids, such as an inflatable balloon or sensor (e.g., Doppler or temperature sensor), to locate the arteriotomy. The targeting aid may be positioned at the arteriotomy. An ultrasonic beacon on the catheter may then be located relative to a therapeutic ultrasonic applicator (e.g., by using acoustic time-of-flight) so that the focus of ultrasonic energy from the applicator can be aligned with the arteriotomy.01-10-2013
20100331741Medical treatment system including an ancillary medical treatment apparatus with an associated data storage medium - A medical treatment system includes an electronic controller with a medical treatment apparatus, a data reader, an ancillary treatment apparatus used with the electronic medical treatment apparatus and a data storage medium associated with the ancillary treatment apparatus. The controller is configured to receive information from the data storage medium, and to control the medical treatment apparatus with medical treatment parameters compatible with the desired medical treatment and the ancillary treatment apparatus.12-30-2010
20110306904ABLATION DEVICES AND RELATED METHODS THEREOF - The present invention relates generally to devices for performing targeted tissue ablation in a subject. In particular, the present invention provides devices configured to deliver energy to a targeted tissue region without causing damage to untargeted tissue.12-15-2011
20100113984Geometrically shaped hydrogel standoffs for coupling high intensity focused ultrasound - In vivo biocompatible hydrogels to couple and transmit high intensity ultrasound for hemostasis and ablation during surgery, the hydrogels having 4-40 wt. % of a polymer comprising acrylates and the balance water. A group of hydrogels based on cross-linked methacrylate one of which is polyethyleneglycol methacrylate, can form rigid, low acoustic attenuation coupling members and are in vivo biocompatible. These coupling members consist of hydrogel formulations having mechanical and acoustic properties such that ultrasound transmission standoff members of various dimensions and structural configurations function as efficient ultrasound transmission media and devices within which the ultrasound beam can be transferred to a focal point at the end of the standoff or in close proximity to it.05-06-2010
20080214964Therapeutic Endocavity Probe Comprising an Image Transducer Integrated Within the Therapy Ultrasonic Transducer - A therapeutic endocavity probe for treating tissues in particular of the prostate by emission of focused ultrasonic waves, including a support forming a guide tube extended by a mounting head for at least one therapy transducer component with an active surface emitting focused ultrasonic waves and having a spherical front of a total surface area in which a surface window is laid out for mounting an imaging transducer. According to the invention, the therapy transducer component has a front face having a total surface area equal to the sum of the active surface area equal to 1,500 mm09-04-2008
20080319355Ischemic stroke therapy - A method for delivering ultrasound energy to a patient's intracranial space includes the steps of forming a hole in a patient's skull, locating an ultrasound transmitter near or into the hole, and transmitting ultrasound from the transmitter into the intracranial space, wherein the Mechanical Index of ultrasound energy traveling through cerebral tissue in the intracranial space is less than 1.0, the power intensity delivered to a target tissue in the intracranial space is greater than 50 mW/cm12-25-2008
20090149782Non-Invasive Neural Stimulation - The present invention is a system for the non-contact stimulation of excitable tissue. A primary purpose is reducing the perception of pain in those people who suffer from persistent pain. Apparatus is described for adjusting the position of the stimulation region.06-11-2009
20110046522Ultrasound Energy Delivery Assembly - In a first embodiment, an ultrasound energy delivery assembly includes a waveguide and a catheter having a capture member. The capture member extends radially inward from an interior surface of the catheter into a lumen of the catheter and is configured to retain the enlarged distal tip so that the enlarged distal tip is temporarily prevented from moving proximally. In a second embodiment, an ultrasound energy delivery assembly includes a waveguide and a sheath covering at least a portion of the waveguide. In a third embodiment, an ultrasound energy delivery assembly includes a waveguide and a dual lumen catheter having a capture member. In a fourth embodiment, an ultrasound energy delivery assembly includes a waveguide and a catheter having a proximal waveguide lumen and a proximal guide wire lumen that merges with the proximal waveguide lumen at their respective distal ends to form a distal lumen. In a fifth embodiment, an ultrasound energy delivery assembly includes a waveguide and a catheter having a helical spring tip disposed over a distal section of the waveguide. In a sixth embodiment, an ultrasound energy delivery assembly includes a waveguide and a catheter extruded from a material such as expanded polytetrafluoroethylene. The catheter includes a braided layer having a multi-wire braided section and a single wire braided section formed from a braid wire from the multi-wire braided section.02-24-2011
20090099484COATING OF POLYURETHANE MEMBRANE - There is provided a vibration delivery system that includes one or more vibrating elements, a vibration focusing element and a protective coating on said focusing element.04-16-2009
20100069797PULSED CAVITATIONAL ULTRASOUND THERAPY - Therapy methods using pulsed cavitational ultrasound therapy can include the subprocesses of initiation, maintenance, therapy, and feedback of the histotripsy process, which involves the creation and maintenance of ensembles of microbubbles and the use of feedback in order to optimize the process based on observed spatial-temporal bubble cloud dynamics. The methods provide for the subdivision or erosion of tissue, liquification of tissue, and the enhanced delivery of therapeutic agents. Various feedback mechanisms allow variation of ultrasound parameters and provide control over the pulsed cavitational process, permitting the process to be tuned for a number of applications. Such applications can include specific tissue erosion, bulk tissue homogenization, and delivery of therapeutic agents across barriers.03-18-2010
20080294072MESOTHERAPY WITH ULTRASOUND - Mesotherapy with ultrasound delivered at 1 to 3 Mhz for five minutes before and five minutes after a phosphatidylcholine-deoxycholate solution is injected into the areas of unwanted fat.11-27-2008
20090171253SYSTEM AND METHOD FOR DERMATOLOGICAL TREATMENT USING ULTRASOUND - An handpiece including an ultrasound transducer is used for dermatological applications such as skin tightening or hair removal. The handpiece is configured to monitor whether a bone of the patient underlies the ultrasound transducer. In a preferred embodiment, the transducer generates a sounding pulse. The reflection of the pulse off the bone is measured. In response to the detection of the bone, the treatment can be modified or halted to protect the bone.07-02-2009
20120059285METHOD AND APPARATUS FOR TREATMENT OF INTRACRANIAL HEMORRHAGES - An ultrasound catheter with a lumen for fluid delivery and fluid evacuation, and an ultrasound source is used for the treatment of intracerebral or intraventricular hemorrhages. After the catheter is inserted into a blood clot, a lytic drug can be delivered to the blood clot via the lumen while applying ultrasonic energy to the treatment site. As the blood clot is dissolved, the liquefied blood clot can be removed by evacuation through the lumen.03-08-2012
20120004580APPARATUS AND METHOD FOR STIMULATION OF BIOLOGICAL TISSUE - An apparatus for generating focused currents in biological tissue is provided. The apparatus comprises an electric source capable of generating an electric field across a region of tissue and means for altering the permittivity of the tissue relative to the electric field, whereby a displacement current is generated. The means for altering the permittivity may be a chemical source, optical source, mechanical source, thermal source, or electromagnetic source.01-05-2012
20120209151SKIN TREATMENT DEVICE WITH AN INTEGRATED SPECIMEN DISPENSER - An electronic skin treatment device with an integrated specimen dispenser is disclosed, with which specimen dispense can be concurrently applied to target skin area while ultrasonic vibrations, mechanical massaging motions, galvanic stimulations, or light illuminations are used and as such a customizable, easier and better skin beautification can be achieved.08-16-2012
20120209150Sub-Aperture Control in High Intensity Focused Ultrasound - Sub-aperture control is provided for high intensity focused ultrasound. Test transmissions are made sequentially from different sub-apertures. The tissue response at the focal regions is determined and used to select sub-apertures. For example, one or more sub-apertures are not used where temperature does not rise above certain threshold or tissue displacement is weak, such as associated with intervening bone or attenuating tissue. Other factors may be used instead or in addition to tissue response at the focal region. Relative proximity of the sub-apertures to a lesion, angular distribution of the sub-apertures, shape or size of the sub-aperture focal regions as compared to the tissue to be treated, or combinations thereof may be used. Once selected, the relative weight for each sub-aperture may be adjusted based on measured tissue response for each sub-aperture, such as to provide more equal treatment contribution from different sub-apertures.08-16-2012
20120010539OPERATION DEVICE AND SURGICAL APPARATUS - An operation device configured to control driving of an apparatus, includes a switch contact point which is provided in a fixed handle, and a switch operation portion which includes a pressure-receiving portion configured to operate the switch contact point between an open state and a closed state in accordance with a pressing state of the pressure-receiving portion. The operation device includes a support portion configured to support the pressure-receiving portion in such a manner that the pressure-receiving portion can incline and move with respect to the fixed handle about an inclination movement center, the support portion being configured to support the pressure-receiving portion in such a manner that the user can press the pressure-receiving portion in a direction where the inclination movement center of the pressure-receiving portion is arranged in a state in which the pressure-receiving portion is inclined and moved and in a neutral position state.01-12-2012
20120010538PRE-COLLAPSED CMUT WITH MECHANICAL COLLAPSE RETENTION - A CMUT transducer cell suitable for use in an ultrasonic CMUT transducer array has a membrane with a first electrode, a substrate with a second electrode, and a cavity between the membrane and the substrate. The CMUT is operated in a precollapsed state by biasing the membrane to a collapsed condition with the floor of the cavity, and a lens is cast over the collapsed membrane. When the lens material has polymerized or is of a sufficient stiffness, the bias voltage is removed and the lens material retains the membrane in the collapsed state.01-12-2012
20120010537IMPROVED ULTRASONIC SURGICAL TOOL - The shaped output is for use with an ultrasonic surgical tool vibratable in torsional mode. The output has a generally cylindrical first waveguide (01-12-2012
20120010541Pulsed Cavitational Ultrasound Therapy - Therapy methods using pulsed cavitational ultrasound therapy can include the subprocesses of initiation, maintenance, therapy, and feedback of the histotripsy process, which involves the creation and maintenance of ensembles of microbubbles and the use of feedback in order to optimize the process based on observed spatial-temporal bubble cloud dynamics. The methods provide for the subdivision or erosion of tissue, liquification of tissue, and/or the enhanced delivery of therapeutic agents. Various feedback mechanisms allow variation of ultrasound parameters and provide control over the pulsed cavitational process, permitting the process to be tuned for a number of applications. Such applications can include specific tissue erosion, bulk tissue homogenization, and delivery of therapeutic agents across barriers.01-12-2012
20110166484ULTRASONIC TREATMENT APPARATUS WITH A PROTECTIVE COVER - An ultrasonic treatment apparatus comprised of: a patient support for supporting a patient, an ultrasound transducer system for ultrasonic treatment of the patient, a region formed in the patient support operable for transmitting ultrasound from the ultrasound transducer system to a treatment zone in the patient, a protective cover for covering the region, and wherein the protective cover is adapted to be removed from the region while the patient is positioned relative to the treatment zone such that the treatment zone is able to receive treatment from the ultrasound transducer system.07-07-2011
20110166483ULTRASONIC CURVED BLADE - An ultrasonic dissection and coagulation system for surgical use is provided. The system includes an ultrasonic instrument, a control module, and a remote actuator. The ultrasonic instrument has a housing and an elongated body portion extending from the housing. An ultrasonic transducer supported within the housing is operatively connected to a cutting jaw by a vibration coupler. The vibration coupler conducts high frequency vibration from the ultrasonic transducer to the cutting jaw. The cutting jaw has a blade surface which is curved downwardly and outwardly in the distal direction with respect to the longitudinal axis of the elongated body portion along its length such that an angle defined by a line drawn tangent to the blade surface and the longitudinal axis of the elongated body portion varies between 5 degrees and 75 degrees. A clamp member having a tissue contact surface is positioned adjacent to the cutting jaw and is movable from an open position in which the tissue contact surface is spaced form the blade surface to a clamped position in which the tissue contact surface is in close juxtaposed alignment with the blade surface to clamp tissue therebetween. The clamp member and the curved cutting jaw combine to enhance contact between tissue and the blade surface of the cutting jaw during cutting. Further, the continuously varying angle of the blade surface with respect to the longitudinal axis of the elongated body portion facilitates selective user control over the application of force on tissue during a cutting or dissecting procedure.07-07-2011
20110166482SYSTEM AND METHOD FOR TRANSVASCULARLY STIMULATING CONTENTS OF THE CAROTID SHEATH - Methods and systems are disclosed for stimulating contents of the carotid sheath using an intravascular pulse generator and lead. The lead carries an energy delivery device such as an electrode, which is anchor within the portion of the internal jugular vein that is disposed within the carotid sheath. The energy delivery device is energized to transvenously direct energy to target contents of the carotid sheath external to the internal jugular vein. Such target contents may include nervous system elements associated with the carotid sinus baroreceptors, the carotid sinus nerve and associated nerve branches, and or the vagus nerve and associated nerve branches. The system may be used to control blood pressure and/or to lower heart rate and may be suitable for treatment of hypertension, heart failure, or other conditions.07-07-2011
20120016272ULTRASOUND CATHETER DEVICES AND METHODS - Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and a distal head coupled with the transmission member and positioned adjacent the distal end of the catheter body for disrupting occlusions. Improved features of ultrasound catheters include prevention of independent rotation of the ultrasound transmission member, a safety anchor for the distal head, a one-piece transmission member/distal head and the like.01-19-2012
20120116269OCCLUSION APPARATUS - Methods, apparatus, and systems for occluding a left atrial appendage are provided. One embodiment includes an elongate body having a tissue apposition member extendably positioned within a lumen of the elongate body to appose tissue of the LAA. An energy emitting device coupled to the elongate body can be used for emitting high intensity focused ultrasound to the tissues to fuse the tissues.05-10-2012
20120116267USER FEEDBACK THROUGH END EFFECTOR OF SURGICAL INSTRUMENT - A surgical instrument includes a handle assembly and a transmission assembly including an end effector. The end effector includes a visual indicator, such as dots disposed on a clamp arm, to emit light from at least one LED disposed between the clamp arm and a clamp pad. The LED is connectable to a power source. An outer sheath of the end effector is extruded to include a first set of electrical conduits. A distal assembly of the end effector includes the clamp arm, clamp pad, LED, and a second set of electrical conduits to mate with the first set of electrical conduits when the distal assembly is snap-fit into the extruded outer sheath. An ultrasonic surgical instrument includes an outer sheath configured to transmit light from an internally housed LED along portions of the outer sheath.05-10-2012
20120116265SURGICAL INSTRUMENT WITH CHARGING DEVICES - A surgical instrument includes a first power source and a second power source. The first power source is configured to deliver power to a surgical instrument at a first rate of discharge. The second power source is configured to deliver power to the first power source at a second rate of discharge. The first power source and the second power source are positioned within the surgical instrument. The first power source and the second power source are further configured to communicate with a control module. The control module may rely on power from the first power source to drive an end effector of the surgical instrument. The end effector may comprise a harmonic/ultrasonic blade, RF electrosurgical electrodes, powered cutting/stapling features, and/or various other types of components.05-10-2012
20120116263GEAR DRIVEN COUPLING BETWEEN ULTRASONIC TRANSDUCER AND WAVEGUIDE IN SURGICAL INSTRUMENT - A surgical instrument is separable into a transducer unit and a lower body portion. The lower body portion includes a waveguide and a casing. The transducer unit includes a transducer and a geared mechanism operable to couple the transducer to the waveguide. In some versions the geared mechanism includes bevel gears coupled to a rack and pinion such that linear motion may be used to rotatably couple a transducer to a waveguide. The rack gear may further include a handle extending out of the transducer unit casing to be actuatable by a user. The rack gear may also be flexible or rigid. In other versions, the bevel gears may be coupled to a threaded shaft that is operable to translate the transducer into the waveguide to form an interference fit. The transducer unit may also include a slide lock mechanism to couple to the casing of the lower body portion.05-10-2012
20120016271METHOD AND GEL COMPOSITION TO PREVENT REFLECTION OF HIFU AT TISSUE-AIR INTERFACE - In order to reduce reflection and heating of a high intensity focused ultrasound (HIFU) beam following a region of interest in tissue to which an HIFU beam was administered, at least two layers of aquasonic gel are applied at a tissue/air interface following the region of interest and the focus in a direction of propagation of the HIFU beam. A first of the two aquasonic gel layers is a foamed aquasonic gel layer, and a second of the two layers is substantially bubble-free aquasonic gel. The layer of foamed aquasonic gel is placed directly adjacent the tissue/air interface, and the layer of substantially bubble-free aquasonic gel is placed over the layer of foamed aquasonic gel, at a side thereof facing away from the tissue/air interface.01-19-2012
20130012838SYSTEMS AND METHODS FOR COUPLING AN ULTRASOUND SOURCE TO TISSUE - Various embodiments provide a system for providing a constant average output of power from an ultrasound source. In some embodiments, the system comprises an ultrasound transducer coupled to a power supply; a controller in communication with the power supply; a chirp function in communication with and operable to monitor the ultrasound transducer; a feedback loop from the chirp function to the controller. In some embodiments, the controller is operable to change a parameter on the transducer based on the feedback to provide a constant average output of power from the ultrasound transducer.01-10-2013
20120022409ENERGETIC MODULATION OF NERVES - A system for applying focused ultrasound energy to a nerve surrounding an artery of a patient includes a piezoelectric array comprising a plurality of piezoelectric elements, a controller configured to control at least a subset of the piezoelectric elements so that at least one of the piezoelectric elements in the subset is in a signal transmitting mode, in a signal sensing mode, or both, a first platform on which the piezoelectric elements are coupled and a second platform, wherein the second platform is configured to support at least a part of the patient, a programmable generator configured to generate output power for one or more of the piezoelectric elements, and a programmable processor configured to process a signal sensed by at least one of the piezoelectric elements.01-26-2012
20110082396Ultrasound-enhanced stenosis therapy - Apparatus and methods are disclosed for vascular stenosis and vulnerable plaque therapies, including enhancing permeability of the vessel wall using ultrasound energy and delivering a therapeutic agent into the arterial wall. Ultrasound energy may also be delivered at frequencies less than 10 MHz and power less than 20 watts using transcutaneous techniques and endovascular methods. Therapeutic agents may be delivered to the treatment area via intravenous and endovascular methods. In some embodiments, ultrasound energy and therapeutic agent application may be combined with angioplasty techniques and with blood flow protection devices.04-07-2011
20110082395MEDICAL THERAPY DEVICE - The medical therapy device includes at least one picture-providing locating device, a treatment device, a patient rest, means for the motorized positioning of at least the treatment device relative to the patient rest, means for control of the therapy device, and a display and operating device. The treatment center of the treatment device may be represented on the display in at least one picture of the locating device on the display, and operating elements are provided, with which the positioning in coordinates of the locating device may be controlled.04-07-2011
20120059289COUPLING ARRANGEMENTS AND METHODS FOR ATTACHING TOOLS TO ULTRASONIC SURGICAL INSTRUMENTS - An ultrasonic surgical instrument that has a waveguide that protrudes distally from the handpiece and a surgical tool that is configured to be coupled to the waveguide upon application of thermal energy to the waveguide or the surgical tool.03-08-2012
20120059288METHOD AND SYSTEM FOR ULTRASOUND TREATMENT WITH A MULTI-DIRECTIONAL TRANSDUCER - A method and system for ultrasound treatment utilizing a multi-directional transducer to facilitate treatment, such as therapy and/or imaging or other tissue parameter monitoring, in two or more directions. In accordance with an exemplary embodiment, a multi-directional transducer comprises at least two transduction elements configured to provide for ultrasound energy, such as radiation, acoustical energy, heat energy, imaging, positional information and/or tissue parameter monitoring signals in two or more directions. The transduction elements can comprise various materials for providing ultrasound energy or radiation, such as piezoelectric materials, with and without matching layers. In addition, the transduction elements can be configured for substantially uniform, focused and/or defocused radiation patterns, as well as for single, multiple-element and/or multiple-element array configurations. In addition, an exemplary multi-directional transducer can comprise multiple elements, either side by side, stacked or in an array.03-08-2012
20120059287ULTRASOUND STIMULATION DEVICES AND TECHNIQUES - Ultrasound stimulation devices and related techniques are disclosed. An ultrasound transducer for generating ultrasound energy is carried by a transducer housing that seals the transducer and may also include a positioning element for positioning the transducer proximate an application area to which generated ultrasound energy is to be applied. The transducer housing may also carry such components as a battery, a wireless receiver, and a controller. The same housing or a separate sensor housing may include an ultrasound sensor that provides feedback to the ultrasound transducer or its controller, illustratively through a wireless transmitter.03-08-2012
20120059286Self-Powered Ablation Catheter for Renal Denervation - An ablation catheter includes a flexible shaft having length sufficient to access a patient's renal artery. An electrode arrangement is provided at the distal end of the shaft. A handle unit includes a housing configured for hand-held manipulation and is coupled to the catheter. A battery and one or both of a high frequency AC generator and ultrasound generator are provided in the housing. The battery serves as the sole source of power for the generator. The generator is configured to generate energy sufficient to ablate perivascular renal nerve tissue using energy stored in the battery. The catheter may be disposable and the housing re-usable. Both the catheter and the housing may be disposable.03-08-2012
20120065553MEDICAL DEVICE - A medical device comprising a hollow probe, ultrasound generation means and suction monitoring means, wherein, in use, suction is applied through the hollow probe and the ultrasound generation means is adjusted in response to a suction flow rate detected by the suction monitoring means. The medical device may also comprise a temperature sensor, in which case the ultrasound generation means is adjusted in response to the temperature detected by the sensor. The medical device may also comprises at least one chuck for reversibly fixing the probe to the body of the device. The medical device may also comprise an integration unit, the body of the device being connected to the integration unit and the integration unit comprising a docking station for at least one battery and means to monitor the operation of the device. Use of the medical device is also claimed.03-15-2012
20120065554Dual Balloon Ablation Catheter with Vessel Deformation Arrangement for Renal Nerve Ablation - A balloon arrangement provided at a distal end of the catheter is configured for deployment within a vessel and comprises a distal balloon and a proximal balloon spaced apart from the distal balloon. An ablation arrangement is provided at the distal end of the catheter and configured to ablate target tissue proximate the vessel. A vessel deformation arrangement comprises at least a portion of the balloon arrangement and is configured to draw a wall segment of the vessel and the target tissue inwardly towards the ablation arrangement. The vessel deformation arrangement may include a port provided in a section of the shaft between the distal and proximal balloons. The port and balloon arrangement are configured to cooperatively draw the wall segment of the vessel and the target tissue inwardly towards the ablation arrangement in response to a negative pressure developed at the port.03-15-2012
20120065551System and Methods of Tissue Microablation Using Fractional Treatment Patterns - An apparatus for treating tissue includes a first energy application device to direct energy at tissue of a patient to cause at least one channel to be formed and a controller to control application of energy from the first energy application device to form the at least one channel. The at least one channel may be in the shape of a spiral-like shape or may be in a flower-like shape. Mechanisms are provided to help open channels formed in the human skin structure. A second energy application source may be used to maintain the channel open after formation. The controller may cause the first energy application device to form a plurality of channels of varying depth, width and distribution over the human skin surface. The apparatus to control the application of energy may be operated using a foot-activated pedal.03-15-2012
20120157888Device for generating an ultrasonic field and method of lypolysis - The invention relates to a device for generating an ultrasonic field having frequencies between 0.9 MHz and 4 MHz in an object, preferably in water or in human tissue, the device comprising a piezo element (06-21-2012
20120116266SURGICAL INSTRUMENT WITH MODULAR END EFFECTOR AND DETECTION FEATURE - An apparatus comprises a handle assembly, a first transmission assembly, and a second transmission assembly. The first transmission assembly is in selective communication with the handle assembly and is operable to deliver energy to a surgical site. The second transmission assembly is in selective communication with the handle assembly and is operable to deliver energy to a surgical site. The first transmission assembly and the second transmission assembly are operable in different modalities, such as ultrasonic and RF electrosurgical modalities, using the same handle assembly.05-10-2012
20120116264SURGICAL INSTRUMENT WITH ULTRASONIC TRANSDUCER HAVING INTEGRAL SWITCHES - An ultrasonic surgical device comprises a handle assembly, a shaft assembly, and a removable transducer module. The transducer module includes a waveguide, a locking mechanism, and an electronics assembly including at least one button. The handle assembly includes a trigger assembly configured to actuate the button(s) of the electronics assembly when the transducer module is coupled with the handle assembly. The shaft assembly engages the waveguide of the transducer module and is disposed at the distal end of the handle assembly. The distal end of the shaft assembly includes a harmonic blade. When assembled with the handle assembly, the transducer module is capable of providing ultrasonic energy to the harmonic blade.05-10-2012
20110092862COUPLING MATERIAL - A solid coupling material for conducting ultrasound from an ultrasound source to a surface, wherein the material maximises contact with the surface and the ultrasound source such that there are minimal or no air gaps in the interface between the surface and the material and in the interface between the ultrasound source and the material.04-21-2011
20110092861ELECTROACOUSTIC TRANSDUCER - An electroacoustic transducer is provided, particularly for use in an apparatus for medical shock-wave treatment. The transducer includes several piezoelements arranged next to one another, which are embedded in a composite mass in a carrier-free manner.04-21-2011
20120071795DERATING METHOD FOR THERAPEUTIC APPLICATIONS OF HIGH INTENSITY FOCUSED ULTRASOUND - Methods of derating a nonlinear ultrasound field and associated systems are disclosed herein. A method of derating a nonlinear ultrasound field in accordance with an embodiment of the present technology can include, for example, calibrating an ultrasound source to a first source voltage (V03-22-2012
20120071794Robotic System for Delivering Energy for Treatment of Skin of a Subject - A robotic system for delivering energy for medical or cosmetic treatment of a region of skin of a subject includes a multi-axis robotic arm mounted on a base and terminating at a holder. An applicator for delivering energy to the skin is mounted in the holder. The holder has at least three range sensors generating outputs of a distance to at least three spaced apart locations on the surface of the skin. A controller associated with the robotic arm and the range sensors processes the outputs from the at least three range sensors to determine an orientation of the holder relative to the skin, and actuates the robotic arm to adjust an orientation of the holder such that an orientation of the applicator relative to the skin is maintained within a predefined range of desired angles.03-22-2012
20120157889MEDICAL DEVICE - A medical device includes a treatment module configured to apply a medical treatment and one or more storage devices storing a device identifier that identifies the medical device. The medical device also includes one or more processing devices configured to control the treatment module to apply a medical treatment, collect compliance information that reflects a patient's compliance with a treatment regimen, access the device identifier from the one or more storage devices, and send the collected compliance information with the accessed device identifier to a server system. The server system is configured to receive the compliance information and the device identifier, determine a patient identifier based on the device identifier, store the compliance information in association with the determined patient identifier, and provide access to the compliance information in response to an inquiry.06-21-2012
20110066084APPARATUS AND METHODS FOR THE DESTRUCTION OF ADIPOSE TISSUE - Methods and apparatus are described for modifying unwanted tissue for cosmetic reasons. The methods provide a non-invasive manner to perform body contouring by destroying adipose tissue while simultaneously causing collagen contraction in a single procedure so that as destroyed tissue is removed from a treatment volume, the volume shrinks gradually to maintain the skin tone of the treatment area.03-17-2011
20110066083Ultrasonic apparatus and method for treating obesity or fat-deposits or for delivering cosmetic or other bodily therapy - A wearable treatment or therapy apparatus for provision of an acoustically enabled or acoustically enhanced treatment or therapy to a patient or treatment subject is provided. Also provided are apparatuses for delivering an acoustic or acoustically-aided therapy or treatment to a patient or treatment-subject.03-17-2011
20110105960Ultrasound-enhanced Stenosis therapy - Apparatus and methods are disclosed for vascular stenosis and vulnerable plaque therapies, including enhancing permeability of the vessel wall using ultrasound energy and delivering a therapeutic agent into the arterial wall. Ultrasound energy may also be delivered at frequencies less than 10 MHz and power less than 20 watts using transcutaneous techniques and endovascular methods. Therapeutic agents may be delivered to the treatment area via intravenous and endovascular methods. In some embodiments, ultrasound energy and therapeutic agent application may be combined with angioplasty techniques and with blood flow protection devices. In some other embodiments, a therapeutic agent may be removed from the body after exposure to the vessel wall to minimize a systemic effect of the therapeutic drug.05-05-2011
20110105958ULTRASOUND APPARATUS AND METHODS FOR MITIGATION OF NEUROLOGICAL DAMAGE - This invention discloses methods and devices using ultrasound energy for use before, during or after surgery for providing a therapeutic effect on nerve tissue. The disclosure describes the use of ultrasound devices consisting of an ultrasound generator, ultrasound transducer and ultrasound horn at least partially enclosed by a shield to enhance neurogenesis on neurons of the central nervous system and other nerve tissue. The shield allows the application of therapeutic levels of ultrasound to nerve tissue to enhance the regeneration of the nerve tissue and mitigate damage to the nerve tissue. The shield serves to protect patient from unwanted contact with portions of the ultrasound horn not being utilized for therapeutic effect. The ultrasound application may be included in devices that have other uses such as a cutting edge for removing tissue.05-05-2011
20110105959Novel Methods for Bone Treatment by Modulating an Arachidonic Acid Metabolic or Signaling Pathway - Methods for promoting osteogenesis to accelerate or enhance bone fracture healing, treat bone defects, and enhance bone formation are disclosed. The methods rely on in vivo or ex vivo modulation of an arachidonic acid metabolic or signaling pathway in general, and, in particular, utilize 5-lipoxygenase inhibitors, leukotriene A4 hydrolase inhibitors, and/or leukotriene B4 receptor antagonists. These molecules can be delivered alone or in combination with one or more agents that inhibit bone resorption, regulate calcium resorption from bone, enhance bone accumulation, enhance bone formation, induce bone formation, impair growth of microorganisms, reduce inflammation, and/or reduce pain.05-05-2011
20100094180APPARATUS FOR TREATING PATIENTS SUFFERING FROM VASCULAR DISEASE BY MEANS OF INFRA,-AUDIBLE-AND ULTRASOUND WAVES - An apparatus treats patients suffering from vascular disease with infra-, audible- and ultrasound waves. The apparatus includes a treating head for emitting sound waves with frequencies ranging from 1 Hz to 100 kHz and feeding introducing the sound waves through a coupling medium into a body portion to be treated, an electronics connected to the treating head for energizing the treating head to emit the sound waves, and a control panel connected to the electronics to choose the electronic waveform of the energizing.04-15-2010
20100094178Systems and Methods for Ultrasound Treatment of Thyroid and Parathyroid - A treatment device and methods for HIFU treatment of thyroid and parathyroid disorders are provided. The treatment method comprises identifying a treatment zone and directing high intensity focused ultrasound energy towards the treatment zone. The treatment device comprises the first sensor for detecting swallowing motion and the second sensor for tracking the motion of the thyroid and parathyroid tissue with ultrasound imaging. Thus, the treatment device allows for safe and non-invasive use of HIFU on thyroid and parathyroid tissue of patients by synchronizing HIFU pulse delivery with patient swallowing and/or directing the applicator of HIFU energy to follow the appropriate tissue when the patient moves.04-15-2010
20120123304MOVING STANDING WAVES - A method of treating a region of tissue with ultrasound, the method comprising: generating a first ultrasound standing wave (USW) pattern at a first frequency in the region; and simultaneously generating a second USW pattern in the region spatially overlapping the first USW pattern at a second frequency different from the first frequency.05-17-2012
20120316473METHODS AND SYSTEMS FOR CONTROLLING AN ULTRASONIC HANDPIECE BASED ON SENSED PRESSURE - A system includes a handpiece configured to generate vibratory energy, and a generator coupled to the handpiece. The generator includes a processing device and a memory device having encoded thereon computer-readable instructions that are executable by the processing device to perform functions including receiving a pressure signal from the handpiece. The pressure signal is indicative of a pressure between the handpiece and a surgical implement. The functions further include determining the pressure between the handpiece and the surgical implement, comparing the pressure to a predetermined pressure range, and transmitting a control signal to the handpiece when the pressure is within the predetermined pressure range.12-13-2012
20120316472ULTRASONIC HANDPIECE - An ultrasonic handpiece includes a horn and a transducer system. The transducer system is configured to detect a first pressure applied to at least a first portion of the transducer system, transmit a signal associated with the first pressure, and generate ultrasonic vibratory energy. The first pressure is associated with a second pressure applied to the horn.12-13-2012
20120123303Minimally Invasive Access for Renal Nerve Ablation - An elongated flexible medical device is inserted into a patient's body via a natural orifice, and advanced through the natural orifice to a location proximate innervated tissue that influences renal sympathetic nerve activity. The medical device can be advanced into a body organ and to a location within the organ proximate the innervated tissue. The organ may comprise an organ of the gastrointestinal tract or urinary tract. The medical device may be advanced through and beyond an access hole in a wall of the organ, and situated at a location proximate the innervated tissue. One or both of imaging and ablation energy is delivered from a distal end of the medical device to the innervated tissue. Innervated renal tissue can be ablated using various forms of energy, including RF energy, ultrasound energy, optical energy, and thermal energy.05-17-2012
20120123302Multiple-Frequency Ultrasonic Phased Array Driving System - An apparatus for sonicating a patient includes an ultrasound array having a plurality of transducers; a driving module for driving said transducers; and a control kernel for causing said driving module to drive said transducers concurrently at two different frequencies.05-17-2012
20100249670HIGH-POWER MULTIPLE-HARMONIC ULTRASOUND TRANSDUCER - A dermatological treatment device that includes an ultrasound transducer and at least one matching layer mechanically interfaced to an output surface of the transducer. The ultrasonic transducer has a fundamental resonant frequency and the at least one matching layer has a thickness about equal to an odd multiple of a quarter-wavelength of the fundamental frequency. A drive circuit applies an electrical power input to the ultrasonic transducer. The electrical power input has a drive frequency that is an odd harmonic of the fundamental resonant frequency of the ultrasonic transducer, and a drive voltage greater than 55 volts. The electrical power input results in an ultrasonic transducer output with a power intensity greater than 150 W/cm09-30-2010
20120232435ULTRASOUND CATHETER AND METHODS FOR MAKING AND USING SAME - Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and, in some embodiments, a guidewire tube extending through the lumen. A distal head for disrupting occlusions is coupled with the distal end of the ultrasound transmission member and is positioned adjacent the distal end of the catheter body. Some embodiments include improved features such as a bend in the catheter body for enhancing positioning and/or advancement of the catheter.09-13-2012
20120130287SELECTIVE REMOVAL OF CELLS HAVING ACCUMULATED AGENTS - A method of treating a condition associate with accumulation of an agent in cells in a patient includes exposing the cells to ultrasound, to selectively kill or induce apoptosis in the cells. The cells include the accumulated agent.05-24-2012
20120130289METHODS FOR RENAL NEUROMODULATION - Methods and apparatus are provided for treating hypertension, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, neuromodulation is applied to neural fibers that contribute to renal function. In some embodiments, such neuromodulation is performed in a bilateral fashion. Bilateral renal neuromodulation may provide enhanced therapeutic effect in some patients as compared to renal neuromodulation performed unilaterally, i.e., as compared to renal neuromodulation performed on neural tissue innervating a single kidney.05-24-2012
20120130288ULTRASOUND-MEDIATED INDUCEMENT, DETECTION, AND ENHANCEMENT OF STABLE CAVITATION - Methods and systems for passively detecting stable cavitation and enhancing stable cavitation during sonothrombolysis are provided. The method of passively detecting stable cavitation includes providing a determined level of ultrasonic energy and detecting a scattered level of ultrasonic energy. The system for inducing and passively detecting stable cavitation includes a dual-element annular transducer array configured to provide a fundamental ultrasonic frequency and to detect an ultrasonic frequency that is a derivative of the fundamental frequency. The method of enhancing stable cavitation includes administering a nucleating agent and a thrombolytic agent to a treatment zone, providing a determined level of ultrasonic energy, and detecting a scattered level of ultrasonic energy.05-24-2012
20120220905METHODS AND PROTOCOLS FOR PROVIDING ARTIFICIALLY INDUCED VIBRATIONS (AIVS) TO MAMMALIAN PATIENTS FOR THERAPEUTIC PURPOSES - The present invention discloses a method of producing therapeutic oscillations useful in treating a mammalian patient comprising steps of: obtaining an artificially induced vibrations device (AIVD) useful for a patients wellness for producing artificially induced vibrations of any of a given frequency, pressure, amplitude, volume and duration according to a protocol; said AIVD comprising: a. plurality of regulators, each of which is adapted to define an AIVD; b. mechanism for producing the protocol of said defined individual AIVs; and, c. effector adapted to introduce said protocol of produced AIVs to impinge in or on at least at least one body portion of a patient; wherein said therapeutic protocol of AIVs comprises two or more different individual time resolved AIVs.08-30-2012
20120215137Apparatus and method for improving blood flow in arterioles and capillaries - Disclosed herein is an apparatus and method which are used to improve blood flow in small vessels such as arterioles and capillaries. Method embodiments of the present invention make use of very high frequency (typically 1 MHZ to 100 MHZ) electrical signals in combination with ultrasonic signals typically falling within the same frequency range, where the frequency of the electrical signals and the ultrasonic signals may be the same or different. The electrical signals and ultrasonic signals are applied to a patient simultaneously, typically at a single contact location which is proximate on the exterior of the body to the arterioles and capillaries where blood flow is impaired.08-23-2012
20100204618ULTRASOUND EQUIPMENT FOR TREATING OF EDEMA AND USE THEREOF - The present invention relates to an ultrasound equipment for treating edema, and more particularly, to an ultrasound equipment to relieve symptoms of edema or repair cellular and tissue edemas by generating 20˜400 mW/cm08-12-2010
20120136280METHOD AND APPARATUS FOR TREATMENT OF ADIPOSE TISSUE - The invention provides methods and apparatuses for the treatment of adipose tissue. The methods comprise application of ultrasound energy to a region of adipose tissue, and the apparatuses comprise at least one source of ultrasound energy configured to direct ultrasound energy through a skin surface into the subcutaneous adipose tissue. In one embodiment, a pressure gradient is created in the region generating relative movement between fat cell constituents having different densities. In another embodiment, a protrusion of skin and underlying adipose tissue containing is formed and ultrasound energy is radiated into the adipose tissue in the protrusion. In another embodiment, an RF electric field is generated inside a region of adipose tissue together with the ultrasound energy.05-31-2012
20120136281PARAMETERS FOR AN ULTRASOUND DEVICE COMPRISING MEANS TO GENERATE HIGH INTENSITY ULTRASOUND BEAM - The present invention relates to a device for treatment of an ocular pathology, the device comprising at least one eye ring (05-31-2012
20120136279ULTRASOUND SURGICAL APPARATUS - An ultrasound surgical apparatus includes: an ultrasound transducer that generates ultrasound vibrations; a driving portion that supplies a driving signal to the ultrasound transducer; a distal end portion that is mechanically coupled with the ultrasound transducer and treats a living tissue through a liquid; a detecting portion that detects a cavitation level signal corresponding to a state of cavitation generated in the liquid by ultrasound vibrations of the distal end portion; and an information acquiring portion that acquires information of the living tissue on the basis of the cavitation level signal.05-31-2012
20120215136MEDICAL DEVICE - A modular medical device includes a core module housing. The core module housing includes a treatment module interface configured to couple to any one of a plurality of treatment modules, and each of the plurality of treatment modules includes a treatment assembly configured to apply a medical treatment. The core housing module contains one or more processing devices coupled to the treatment module interface and configured to determine which particular treatment module, from the plurality of treatment modules, is coupled to the treatment module interface. The one or more processing devices are configured to select, based on the determination, a set of control instructions for the particular treatment module from a plurality of control instructions, and control the particular treatment module using the selected control instructions such that the treatment assembly of the particular treatment module applies the medical treatment for which the treatment assembly is configured.08-23-2012
20110184321HARD TO REACH FRACTURE APPLICATOR STRAP - There may be provided a hard-to-reach fracture applicator strap assembly (07-28-2011
20120083719ULTRASOUND-INTERSECTING BEAMS FOR DEEP-BRAIN NEUROMODULATION - Disclosed are methods and devices for ultrasound-mediated non-invasive deep brain neuromodulation impacting one or a plurality of points in a neural circuit using intersecting ultrasound beams. Depending on the application, this can produce short-term effects (as in the treatment of post-surgical pain) or long-term effects in terms of Long-Term Potentiation (LTP) or Long-Term Depression (LTD) to treat indications such as neurologic and psychiatric conditions. Multiple beams intersect and summate at one or a plurality of targets. The ultrasound transducers are used with control of direction of the energy emission, intensity, frequency (carrier frequency and/or neuromodulation frequency), pulse duration, pulse pattern, and phase/intensity relationships to targeting and accomplishing up-regulation and/or down-regulation.04-05-2012
20120083718Hands-Free Operator-Independent Transcranial Ultrasound Apparatus and Methods - Disclosed is a “hands-free”, autonomously operating, battery-powered apparatus with electronic programmable actuation circuitry for non-invasive ultrasonic treatment of ischemic stroke, microatheromas of the cerebral vasculature, intracranial hypertension, and other cerebrovascular pathologies such as hypoperfusion associated with migraine. The apparatus is provided with registration members to facilitate stereotactic placement of the headset on the skull with respect to target intracranial anatomy. Once fitted in place on the skull and activated, the device does not require clinical intervention during operation; does not need skilled technical adjustment of the waveform patterns; and achieves therapeutic results with power consumption of less than 400 mAmp-hr, thus permitting extended portable operation without external power and eliminating the need for assisted cooling. Using a device of the invention, transcranial ultrasound may be self-administered. The device has application in therapeutic methods, such as methods for treating stroke or migraine, for non-invasively augmenting drug action, and for release or dispersal of endogenous neurovascular mediators.04-05-2012
20120083717Non-Invasive Transcranial Ultrasound Apparatus - Disclosed is an autonomically functioning, battery-powered apparatus for non-invasive delivery of transcranial ultrasound. Insonation is directed by electronic circuitry and programmable instructions in memory and is modulated to achieve stereotemporal modulation of insonation so as to eliminate the need for assisted cooling. The apparatus is provided with registration members to facilitate stereotactic placement of transducer arrays and does not require diagnostic imaging guidance during setup and operation. Insonation is directed by electronic circuitry and programmable instructions in memory and is modulated to achieve stereotemporal modulation of insonation so as to eliminate the need for assisted cooling.04-05-2012
20120172766TREATMENT APPARATUS AND OPERATION SYSTEM - A treatment apparatus of the present invention includes a cavitation generation section that generates cavitations at a treatment target region of a treatment subject; a detection section that detects cavitations that are generated at the treatment target region; and a control section that controls a generation state of cavitations at the treatment target region by controlling a physico-chemical parameter of the treatment target region based on a detection result at the detection section.07-05-2012
20120172765Device and use of a pressure-sound-source for the treatment of fungal diseases - The invention deals with a device and the use of an impulse-sound-source for the treatment of fungal diseases. The treatment of fungal diseases was until recently only possible through fungicides that cause patients strong side effects. The application of acoustic pressure waves in the diseased tissues heals mycoses without causing the mentioned side effects. The sound impulses have a fungicidal effect and ensure the dying off of the fungal colonies.07-05-2012
20100049099METHOD AND SYSTEM FOR POSITIONING AN ENERGY SOURCE - An ablation system for treating atrial fibrillation in a patient comprises an inner shaft having proximal and distal ends as well as a lumen therebetween. A distal tip assembly is adjacent the inner shaft distal end, and the distal tip assembly comprises an energy source and a sensor. The energy source is adapted to deliver energy to a target tissue so as to create a zone of ablation in the target tissue. This blocks abnormal electrical activity and thus reduces or eliminates atrial fibrillation in the patient. The system also has an outer shaft with proximal and distal ends, and a lumen therebetween. The inner shaft is slidably disposed in the outer shaft lumen, and the inner shaft is rotatable, bendable and linearly slidable relative to the outer shaft. The outer shaft is rotatable, bendable and linearly slidable relative to the target tissue.02-25-2010
20100036292OPTIMIZATION AND FEEDBACK CONTROL OF HIFU POWER DEPOSITION THROUGH THE ANALYSIS OF DETECTED SIGNAL CHARACTERISTICS - A system and method for adjusting or selecting the treatment parameters for HIFU signals to treat a target treatment site, and/or to aid in visualizing the likely degree and location of HIFU effects on patient tissue. The system transmits one or more test signals into patient tissue and receives signals created in response to the test signals. The signals are analyzed to determine a response curve of how a characteristic of the signal varies with the one or more test signals. The response curve of the detected signals is used to select a treatment parameter.02-11-2010
20100049101Apparatus and Methods for Delivering Acoustic Energy to Body Tissue - Apparatus for delivering acoustic energy to a target site includes a structure and a transducer secured to the structure, the transducer having a surface configured to be placed on a tissue. The structure comprises a channel located adjacent the transducer, the channel adapted for carrying cooling fluid.02-25-2010
20100049100Systems and methods for applying audible acoustic energy to increase tissue perfusion and/or vasodilation - Systems and methods apply audible acoustic energy to cause vasodilation and/or to increase tissue perfusion.02-25-2010
20100049098Automatic acoustic treatment device - There is provided herein an apparatus for lysing of adipose tissue, comprising a transducer adapted to transmit ultrasound acoustic waves to a target area tissue of a subject body and a controller adapted to automatically trigger the transducer to transmit ultrasound acoustic waves upon receiving indication of said transducer being positioned at a predetermined position (node). There is further provided herein an apparatus for lysing of adipose tissue, comprising a transducer adapted to transmit ultrasound acoustic waves to a target area tissue of a subject body and a positioning element adapted to automatically position the transducer at a predetermined position (node).02-25-2010
20120179073Ischemic Stroke Therapy - A method for delivering ultrasound energy to a patient's intracranial space includes the steps of forming a hole in a patient's skull, locating an ultrasound transmitter near or into the hole, and transmitting ultrasound from the transmitter into the intracranial space, wherein the Mechanical Index of ultrasound energy traveling through cerebral tissue in the intracranial space is less than 1.0, the power intensity delivered to a target tissue in the intracranial space is greater than 50 mW/cm07-12-2012
20100016764Therapeutic Treatment Head, Therapeutic Treatment Appliance, Method of Sequencing Activation Stages for the Head, and Method of Indirectly Determining the Temperature of the Skin - A therapeutic treatment head for treating living tissue (T), the head comprising a casing (01-21-2010
20100010393Treatment of Occlusions by External High Intensity Focused Ultrasound - An apparatus for treating an occlusion in a vessel inside of a patient. The apparatus includes an external high intensity focused ultrasound transducer configured to be positioned outside of the vessel and to emit ultrasonic waves of energy to the occlusion and to detect ultrasonic waves of energy, an internal ultrasound transducer configured to be positioned inside of the vessel at a position adjacent to or inside the occlusion and to emit ultrasonic waves of energy for detection by the external high intensity focused ultrasound transducer, and a controller configured to control the ultrasonic waves of energy emitted by the external high intensity focused ultrasound transducer based on an electrocardiogram of the patient.01-14-2010
20120253237CATHETER WITH MULTIPLE ULTRASOUND RADIATING MEMBERS - A method of delivery ultrasonic energy and a therapeutic compound to a treatment site and an ultrasonic catheter system are disclosed. The ultrasonic catheter system comprises a tubular body having a proximal end, a distal end and a treatment zone located between the distal end and the proximal end, a fluid delivery lumen, at least one ultrasound radiating element positioned in the treatment zone, wiring electrically coupled to the at least one ultrasound radiating element and extending through the tubular body and terminating at a connector, and a control system comprising external circuitry and an isolation pod that is configured to be electrically connected to the connector, the isolation pod being positioned between the tubular body and the external system and comprising an isolation barrier and circuitry for driving the ultrasound radiating element.10-04-2012
20120253238COMPOSITIONS FOR SOLUBILIZING CELLS AND/OR TISSUE - Solubilizing compositions are provided. The compositions comprise at least one zwitterionic surfactant and at least one nonionic surfactant. In one embodiment, the compositions may be useful for solubilizing and remodeling and/or removing tissue on or beneath a patient's skin, optionally in conjunction with the application of energy to a region of interest on the skin. In one embodiment, at least one analyte may be collected and analyzed from the solubilized tissue.10-04-2012
20120253236METHODS AND APPARATUSES FOR DELIVERING EXTERNAL THERAPEUTIC STIMULATION TO ANIMALS AND HUMANS - This invention described herein includes methods and apparatuses for externally delivering therapeutic stimulation to animals and humans to help improve their health, condition and performance. The invention includes various wearable, attachable, and embeddable devices that deliver multiple forms of therapeutic stimulation or vibration such as mechanical, tonal, audio, light, and electrical pulses.10-04-2012
20120316474METHODS AND SYSTEMS FOR CONTROLLING AN ULTRASONIC HANDPIECE BASED ON TUNING SIGNALS - A system includes a handpiece configured to generate vibratory energy and a generator coupled to the handpiece. The generator includes a processing device and a memory device having encoded thereon computer-readable instructions that are executable by the processing device to perform functions including applying a first tuning signal to the handpiece. The first tuning signal has a first variable frequency within a predetermined frequency range. The functions further include detecting a first parameter and a second parameter of the ultrasonic handpiece in response to the first tuning signal, comparing the first parameter to the second parameter, and applying a second tuning signal to the ultrasonic handpiece. The second tuning signal has a second variable frequency within the predetermined frequency range.12-13-2012
20120226200METHODS OF STIMULATING TISSUE BASED UPON FILTERING PROPERTIES OF THE TISSUE - The invention generally relates to methods of stimulating tissue based upon filtering properties of the tissue. In certain aspects, the invention provides methods for stimulating tissue that involve analyzing at least one filtering property of a region of at least one tissue, and providing a dose of energy to the at least one region of tissue based upon results of the analyzing step.09-06-2012
20120259251CONTROLLING ACOUSTIC MODES IN TISSUE HEALING APPLICATIONS - A modal converter assembly for healing tissue, the modal converter assembly comprises a transducer and a body. The transducer is configured to transmit acoustic waves into the tissue from a tissue surface. The body is configured to house the transducer above the tissue surface such that the acoustic waves transmitted into the tissue are transmitted at an oblique angle relative to the tissue surface. The acoustic waves are transferred as shear waves and longitudinal waves to treat a damaged portion of the tissue.10-11-2012
20090048545ULTRASONIC THERAPEUTIC APPARATUS - An ultrasonic therapy device imparts ultrasonic waves to a treatment area in a mouth cavity where an implant treatment has been performed to perform therapy, including: a fitting portion that is fitted and fixed to teeth near the treatment area; a housing that is provided in the fitting portion, is disposed near the treatment area, and in which an opening portion is formed on the side of the treatment area; and an oscillator that is housed in the housing; in which a linear saliva introduction member that is arranged to project outward of the fitting portion or the housing from the opening portion of the housing is provided on the fitting portion or the housing.02-19-2009
20090018471Ultrasonic handpiece - An ultrasonic handpiece is used for augmenting a bone screw. The handpieces comprise a housing, an ultrasonic converter shiftingly accommodated in the housing, and a sonotrode connected to one end of the ultrasonic converter. The sonotrode protrudes from the housing into the bone screw. An adjuster wheel is adjustably connected to the housing. A spring is provided the ends of which are supported by the ultrasonic converter and the adjuster wheel, respectively. The ultrasonic converter is preloaded in the direction away from the adjuster wheel by setting the adjuster wheel, thereby the sonotrode is urged with a selected force into the bone screw and the augmentation material is pressed out of the bone screw and into the bone.01-15-2009
20120259250METHODS OF SOFT TISSUE EMULSIFICATION USING A MECHANISM OF ULTRASONIC ATOMIZATION INSIDE GAS OR VAPOR CAVITIES AND ASSOCIATED SYSTEMS AND DEVICES - The present technology is directed to methods of soft tissue emulsification using a mechanism of ultrasonic atomization inside gas or vapor cavities, and associated systems and devices. In several embodiments, for example, a method of non-invasively treating tissue includes pulsing ultrasound energy from the ultrasound source toward the target site in tissue. The ultrasound source is configured to emit high intensity focused ultrasound (HIFU) waves. The target site comprises a pressure-release interface of a gas or vapor cavity located within the tissue. The method continues by generating shock waves in the tissue to induce a lesion in the tissue at the target site. The method additionally includes characterizing the lesion based on a degree of at least one of a mechanical or thermal ablation of the tissue.10-11-2012
20120232436Method and Apparatus for Treatment of Hypertension Through Percutaneous Ultrasound Renal Denervation - Apparatus and methods for deactivating renal nerves extending along a renal artery of a mammalian subject to treat hypertension and related conditions. An ultrasonic transducer (09-13-2012
20120232434ULTRASOUND CATHETER AND METHODS FOR MAKING AND USING SAME - Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and, in some embodiments, a guidewire tube extending through the lumen. A distal head for disrupting occlusions is coupled with the distal end of the ultrasound transmission member and is positioned adjacent the distal end of the catheter body. Some embodiments include improved features such as a bend in the catheter body for enhancing positioning and/or advancement of the catheter.09-13-2012
20110004128LIGHT IRRADIATION BEAUTY APPLIANCE - A light irradiation cosmetic device (01-06-2011
20110004127Ultrasound treatment system - An ultrasound treatment system comprises an ultrasonic transducer, a handpiece, a probe, a sheath, a clamping member, an operation unit, an operating member, a suction base, and a perfusion base. The ultrasonic transducer generates ultrasonic vibrations. The handpiece has the ultrasonic transducer incorporated therein. The probe is connected to the ultrasonic transducer for transmitting ultrasonic vibrations to a distal member realizing a stationary portion that is a treatment portion for treating a living tissue. The sheath serves as a protecting member for shielding the probe. The clamping member is opposed to the distal member at the distal end of the sheath for clamping a living tissue in cooperation with the distal member. The operation unit is manipulated for clamping a living tissue with the clamping member and distal member or freeing the living tissue therefrom.01-06-2011
20120238918METHODS FOR DELIVERING ENERGY TO MODULATE NEURAL STRUCTURES - In some examples, nerves surrounding arteries or leading to organs are targeted with energy sources to correct or modulate physiologic processes. In some examples, different types of energy sources are utilized singly or combined with one another. In some examples, bioactive agents or devices activated by the energy sources are delivered to the region of interest and the energy is enhanced by such agents or the agents are enhanced by the energy sources.09-20-2012
20120271203POWER PARAMETERS FOR ULTRASONIC CATHETER - An ultrasound catheter system and a method for operating an ultrasonic catheter at a treatment site within a patient's vasculature or tissue are disclosed. The ultrasound catheter system comprises a catheter having at least one ultrasonic element and a control system configured to generate power parameters that drive the at least one ultrasonic element to generate ultrasonic energy. The control system is configured to vary at least one of the power parameters and at least one physiological parameter by repeatedly cycling the power parameter and the physiological parameter through two set of values.10-25-2012
20120265105ULTRASOUND CONSTIPATION RELIEF DEVICE - A therapy device capable of relieving constipation by applying stimulation from a back to a lumbar spine and a vicinity thereof, the device includes: an ultrasound signal oscillation circuit; and a head, which is placeable from the back on at least a region between a third lumbar spine and a fourth lumbar spine, a region between the fourth lumbar spine and a fifth lumbar spine, or any one or two or more of the third lumbar spine, the fourth lumbar spine, and the fifth lumbar spine. The head includes a piezoelectric element, which generates ultrasound capable of being transmitted from the back to the lumbar spine or a region between lumbar spines, and the head is sized to be placeable on the region between the lumbar spines, and is capable of outputting ultrasound vibration having frequency and power capable of stimulating a pressure point or nerve relating to constipation.10-18-2012
20110040212Ultrasonic Surgical Apparatus and Methods for Use Thereof - Ultrasound surgical apparatus are disclosed, including: medical ultrasound handpieces with proximally mounted ultrasound radiators configured to create a distally-focused beam of ultrasound energy, in combination with distal guide members for control of focal point depth; medical ultrasound handpieces with proximally mounted ultrasound radiators configured to create a distally-focused beam of ultrasound energy, in combination with distal rolling members for manipulability and control of focal point depth; medical ultrasound handpiece assemblies with coupled end effectors providing a probe with a probe dilation region configured to have an average outside diameter that is equal to or greater than the average outside diameter of a probe tip and neck; as well as junctions to an ultrasonically inactive probe sheath; medical ultrasound handpiece assemblies with coupled end effectors having positionable, ultrasonically inactive probe sheath ends slidably operable to both cover and expose at least a probe tip; and ultrasound transducer cores including a transducing structure affixed to a longitudinally elongated, generally planar, single crystal or polycrystalline material waveguide.02-17-2011
20110046521Ultra-Sonic and Vibratory Treatment Devices and Methods - An exemplary embodiment provides a hand-held apparatus for treatment of conditions requiring ultra-sonic or vibratory treatment. The apparatus includes a transducer, an electronic tuning circuit and a power source for powering the apparatus. The transducer has a first section axially aligned with the second section. The second section has an outer wall of predetermined thickness surrounding an annular cavity that contains a piezoelectric stack. The electronic tuning circuit is in communication with the piezoelectric stack. The circuit is configured to tune the transducer to a target output frequency. The transducer, electronic tuning circuit and power source are at least partially contained within a common housing that is configured to be grasped by a human hand to administer treatment.02-24-2011
20120271204PHOTOACOUSTIC MEASUREMENT - A method of providing cosmetic treatment of a skin surface of a patient using a photoacoustic system.10-25-2012
20120271202ULTRASONIC THERAPY DEVICE WITH DIFFRACTIVE FOCUSING - A device for selectively treating multiple regions of tissue simultaneously, the device comprising an ultrasound transducer and a plurality of layers. The ultrasound transducer is configured to produce an acoustic wave. The plurality of layers comprises a plurality of cavities, where the plurality of cavities are configured to scatter the acoustic wave and simultaneously produce a plurality of treatment zones at a predetermined distance from the ultrasound transducer.10-25-2012
20120323147ULTRASONIC HIFU TRANSDUCER WITH NON-MAGNETIC CONDUCTIVE VIAS - A high intensity focused ultrasound (HIFU) transducer comprising a piezoelectric array with a layer of piezoelectric material having a patient-facing front surface and a back surface, the front surface comprising a transmitting surface, and a plurality of electrodes located on the front and back surfaces of the piezoelectric material for applying electrical signals to the piezoelectric array. Electrical connections between an electrode on the back surface to an electrode on the front surface of the piezoelectric array are made through non-magnetic conductive vias extending through the layer of piezoelectric material.12-20-2012
20100234773Ultrasonic Therapeutic Means and An Ultrasonic Therapeutic System of Using the Same - An ultrasonic therapeutic means and an ultrasonic therapeutic system including the ultrasonic therapeutic means and guided by an imaging device are provided. The ultrasonic therapeutic means includes an ultrasonic therapeutic applicator (09-16-2010
20110257562METHOD AND APPARATUS EMPLOYING ULTRASOUND ENERGY TO REMODULATE VASCULAR NERVES - Methods and apparatus for treating hypertension and other vessel dilation conditions provide for delivering acoustic energy to a vascular nerve to remodel the tissue and nerves surrounding the vessel. In the case of treating hypertension, a catheter carrying an ultrasonic or other transducer is introduced to the renal vessel, and acoustic energy is delivered to the tissue containing nerves to remodel the tissue and remodulate the nerves.10-20-2011
20120089052Massaging device with multiple ultrasonic transducers - The present invention teaches an ultrasonic device for skin care massage, comprising one or more ultrasonic vibration transmission plates, each of which having a backside and a smooth surface for contacting human skin; and at least two different ultrasonic vibration transducers coupled to a backside of each of the ultrasonic vibration plates. Each of the ultrasonic vibration transducers generates an ultrasonic wave with a unique frequency between 20 kHz to 25 MHz. Each of the ultrasonic vibration transducers has a bottom surface paralleling to the smooth surface. A distance between the bottom surface of any of the ultrasonic vibration transducers to the smooth surface is approximately an integer times of the half wavelength of the ultrasonic wave generated by the ultrasonic vibration transducer.04-12-2012
20120089053METHOD OF APPLYING SHEAR STRESS - An ultrasonic horn for use with an ultrasonic surgical hand piece including a resonator comprises a contacting annulus having a plurality of angled lands. The lands are alternated around the annulus such that adjacent lands have opposite angles. As a result of the adjacent angled lands, a shear stress field is developed in contacted tissue due to the promotion of refracted longitudinal ultrasonic waves propagating in different directions at the interface to the coupled tissue. The shear stress field enhances the fragmentation and removal rate of fibrous, elastic, and tenacious tissue. The horn is hollow permitting suction to be applied to the tissue for controlling tissue contact with the lands.04-12-2012
20120330196Methods and Apparatus for Removing Blood Clots and Tissue from the Patient's Head - Methods and apparatus for removing blood clots and tissue from the intracranial space of a patient's head using a trocar with an ultrasound device and visualization device to locate, dissolve and remove the blood clots outside the patient's head are provided. One or more pharmacologic agents may be delivered to the treatment area to further facilitate removal of the blood clots or other tissue.12-27-2012
20120330195PROBE ADAPTED TO TREAT LIVING TISSUE AND ACTUATION METHOD OF DEVICE - A probe which is configured for a treatment device which is configured to treat a body tissue using ultrasonic vibration, includes a base member which includes a base surface defined by a longitudinal direction and a width direction shorter than the longitudinal direction and which is a vibration-retardation member configured to hardly transmit the ultrasonic vibration, a waveguide main body which has a width smaller than a width of the base surface in a width direction, protrudes with respect to the base surface, and is extended along the longitudinal direction of the base surface, and an end effecter which is provided at a tip end portion of the waveguide main body and which is configured to treat the body tissue by the ultrasonic vibration transmitted through the waveguide main body.12-27-2012
20120330194APPARATUS AND METHOD FOR TREATING TISSUE WITH ULTRASOUND - A treatment apparatus and method are disclosed for applying mechanical ultrasonic vibrations to an area of tissue. The apparatus comprises an applicator movable by an operator over the area of tissue to be treated. Mounted within the applicator are an ultrasonic transducer for generating mechanical vibrations and a sonotrode for transmitting the vibrations generated by the transducer to the tissue to be treated. The apparatus further comprises a sensor for measuring an operating parameter indicative of the efficiency of the acoustic coupling between the sonotrode and the tissue to be treated, and electronic circuitry for generating a signal (e.g. an alarm signal) when the efficiency of the acoustic coupling drops below a threshold.12-27-2012
20120289869DEVICES AND METHODS FOR MODULATING BRAIN ACTIVITY - Devices and methods for brain modulation are provided herein. A device may comprise a body and components for activating the brain. Such components include ultrasound transducers. The devices are used to provide ultrasound waves to brain structures in a subject wearing a device for methods to treat traumatic brain injury, affect postural control, affect wakefulness, attention, and alertness, to provide memory control, to alter cerebrovascular hemodynamics, to minimize stress, and to reinforce behavioral actions.11-15-2012
20130012840SYSTEM AND METHOD FOR ACCELERATING THE RELATIVE PROPORTION OF FAT CATABOLISM - System and method for reducing stored body fats in a treatment region on a body. The system includes an ultrasound apparatus, for transmitting ultrasound waves at the treatment region. The ultrasound waves facilitate the release of triglycerides, fat molecules and toxins from stored fat within the treatment region, achieving the reduction of stored body fats by accelerating the relative proportion of fat catabolism in the treatment region. The treated person may be undergoing a physical exercise substantially concurrently to the ultrasound transmission. Electrical stimulation, such as interferential stimulation, may be applied to the treatment region substantially concurrently to the ultrasound transmission. Pressure may be exerted onto the treatment region substantially concurrently to the ultrasound transmission, such as by kneading a portion of the ultrasound apparatus against the treatment region, or by massaging the treatment region, manually or mechanically with a massaging device.01-10-2013
20100130891Wearable Therapeutic Ultrasound Article - The present invention is directed to a wearable therapeutic article including an ultrasound transducer having a first electrode, a second electrode and a piezoelectric material disposed therebetween, the ultrasound transducer being positioned within a pocket so that, as the user moves, the ultrasound transducer moves to a different position in the pocket.05-27-2010
20130018286SYSTEMS AND METHODS FOR MONITORING AND CONTROLLING ULTRASOUND POWER OUTPUT AND STABILITY - Some embodiments provide a method of providing ultrasound energy having a stable power output. The method can comprise providing ultrasound energy from a ultrasound transducer; determining a power level threshold of the ultrasound energy; monitoring a power level of the ultrasound energy over time of the ultrasound energy; communicating a power level to a controller; adjusting the frequency of the ultrasound energy upon a change in the power level; and maintaining the power level threshold of the ultrasound energy.01-17-2013
20130018285FOCUSED ULTRASOUND THERAPY APPARATUS AND METHOD OF CONTROLLING FOCAL POINTAANM PARK; Jun-hoAACI Hwaseong-siAACO KRAAGP PARK; Jun-ho Hwaseong-si KRAANM LEE; Hyoung-kiAACI Seongnam-siAACO KRAAGP LEE; Hyoung-ki Seongnam-si KRAANM LEE; Ho-taikAACI Yongin-siAACO KRAAGP LEE; Ho-taik Yongin-si KRAANM AHN; Min-suAACI SeoulAACO KRAAGP AHN; Min-su Seoul KRAANM PARK; Ji-youngAACI Yongin-siAACO KRAAGP PARK; Ji-young Yongin-si KR - A method of controlling a focus in a focused ultrasound therapy apparatus, the method including receiving an target area to which ultrasound is radiated to remove a lesion; determining a path through which the focus moves in the target area, depending on a form of the target area; and forming the focus on the determined path and then radiating ultrasound to the target area.01-17-2013
20130018287APPARATUS FOR GENERATING THERAPEUTIC SHOCKWAVES AND APPLICATIONS OF SAME - Apparatuses and methods to generate high frequency shock waves in a controlled manner. The generated shock waves can be delivered to certain cellular structures of a patient for use in medical and/or aesthetic therapeutic applications. The shock waves can be configured to impose sufficient mechanical stress to the targeted cells of the tissue to rupture the targeted cells. Embodiments of the apparatuses and methods of the present invention provide targeted rupturing of specific cells without damaging side effects such as cavitation or thermal degradation of surrounding non-targeted cells.01-17-2013
20100168623ULTRASONIC TREATMENT APPARATUS AND PROGRAM - An ultrasonic treatment apparatus according to the present invention includes: an oscillation unit which selectively oscillates a plurality of ultrasonic signals; a data table which includes a plurality of data rows storing in advance frequency data of the ultrasonic signals, at least one data row among the plurality of data rows storing specific frequency data and other frequency data such that a storage amount of the specific frequency data is larger than that of the other frequency data; an operation unit which select one application data row from the plurality of data rows: a plurality of ultrasonic oscillators which include a plurality of resonance frequencies: a plurality of connectors to which the plurality of ultrasonic oscillators are each connectable; a plurality of switches which are each connected, to the plurality of connectors; and a control unit which, in order to apply an application ultrasonic signal selected based on the application data row among the plurality of ultrasonic signals to one application ultrasonic oscillator among the plurality of ultrasonic oscillators, controls the plurality of switches so as to selectively apply the application ultrasonic signal to an application connector connected to the application ultrasonic oscillator, among the plurality of connectors.07-01-2010
20110160624APPARATUS FOR CREATING A THERAPEUTIC SOLUTION AND DEBRIDEMENT WITH ULTRASOUND ENERGY - An ultrasound surgical apparatus is provided. The apparatus is constructed from a tip mechanically coupled to an ultrasound horn containing an internal chamber. The horn is mechanical coupled to an ultrasound transducer driven by a generator. The ultrasound tip possesses at least one radial surface, a cavity, or some other form of a hollowed out area, within at least one of the radial surfaces, and a sharpened cutting member at the opening of the cavity. The horn contains an internal chamber enabling the creation of therapeutic solution that may serve as or be incorporated into a coupling medium delivered to the cavity of the tip.06-30-2011
20110160623EXTERNAL STIMULATION OF THE SPG - Apparatus is provided for treating a condition of a subject, including an energy transmitter, which is configured to be positioned outside a body of the subject in a vicinity of a site selected from the group consisting of: a sphenopalatine ganglion (SPG), a greater palatine nerve, a lesser palatine nerve, a sphenopalatine nerve, a communicating branch between a maxillary nerve and an SPG, an otic ganglion, an afferent fiber going into the otic ganglion, an efferent fiber going out of the otic ganglion, an infraorbital nerve, a vidian nerve, a greater superficial petrosal nerve, and a lesser deep petrosal nerve. A control unit is configured to drive the energy transmitter to transmit energy to the site, and configure the energy to stimulate the site. Other embodiments are also described.06-30-2011
20110160622PROCESSES AND APPARATUS FOR PREVENTING, DELAYING OR AMELIORATING ONE OR MORE SYMPTOMS OF PRESBYOPIA - The present invention generally relates to an apparatus and processes for preventing or delaying presbyopia. More particularly, the present invention relates to processes and apparatus for ablating epithelial cells in the germinative zone or the pregerminative zone of the crystalline lens of the eye so that onset or progression of presbyopia or one or more symptoms is de-layed or prevented. The present invention also relates to processes and apparatus for promoting formation of suture lines in the crystalline lens of the eye so that onset or progression of presbyopia or one or more symptoms is delayed or prevented. The present invention also relates to processes and apparatus for creating disruptions in the vitreous humor of the eye.06-30-2011
20110160621Methods and apparatus for dissolving intracranial blood clots - A method for dissolving blood clots in a patient's intracranial space using ultrasound energy involves forming at least one hole in the patient's skull, advancing at least one ultrasound delivery device through the hole, and transmitting ultrasound energy from the ultrasound delivery device into blood clots. According to various embodiments, ultrasound delivery devices may be advanced into the epidural space, one or both ventricles and/or an intracerebral space of the patient's brain. Also, one or more pharmacologic agent maybe delivered to the patient intracranial space to further facilitate clot dissolving therapy. Intracranial ultrasound delivery may be used to dissolve intracranial blood clots in relation to ischemic stroke, hemorrhagic stroke, head trauma, atherosclerosis, perfusion disorders and other acute or chronic neurological conditions.06-30-2011
20110160620SYSTEM AND METHOD FOR MINIMALLY INVASIVE TISSUE TREATMENT - Delivering ultrasonic energy to a target musculoskeletal tissue site includes connecting a delivery device to a vacuum source, a fluid source, and a power signal source. The delivery device has a housing portion maintaining an ultrasound transducer and a tip portion having a sleeve and a cannula. The cannula is coupled to the ultrasound transducer and received in the sleeve to define a covered portion and an exposed portion. Ultrasonic energy is generated by sending a power signal from the power signal source to the ultrasound transducer. The ultrasonic energy is transmitted from the ultrasound transducer to the cannula, such that the exposed portion of the cannula delivers ultrasonic energy at a frequency that is pre-selected to debride musculoskeletal tissue upon percutaneous insertion of the tip portion.06-30-2011
20130023801ULTRASONIC TRANSDUCER - An ultrasonic transducer is disclosed, which includes one or a plurality of ultrasonic emitting units. Wavefronts of the ultrasonic waves emitted by the one or the plurality of ultrasonic emitting units are sphere surfaces with uniform radius, and the one or the plurality of ultrasonic emitting units can reflect ultrasound. The one ultrasonic emitting unit is configured to form a spherical resonant cavity, or the plurality of ultrasonic emitting units are configured to form a spherical resonant cavity collectively. An internal cavity of the spherical resonant cavity has a spherical shell shape or a cross-sectional spherical shell shape with a spherical center therein. The ultrasonic waves emitted by the one or the plurality of ultrasonic emitting units are focused on an area in which the spherical center of the spherical resonant cavity is located. The ultrasonic transducer not only can be provided with a large ultrasonic emitting area and a great focusing gain that render the energy of the ultrasonic focus enhanced dramatically, but also can be free from the influence of work frequency of an ultrasonic source.01-24-2013
20080255478ACOUSTIC APPLICATORS FOR CONTROLLED THERMAL MODIFICATION OF TISSUE - An apparatus and method for modifying collagen containing dermal tissue. The apparatus includes a source of ultrasound energy comprised of a plurality of curvilinear ultrasound transducers shaped to direct ultrasound energy to selected skin depths. The transducers have variable curvature, drive frequency, power level and geometries to effect precise control of collagen modification.10-16-2008
20080243035INTERCHANGEABLE HIGH INTENSITY FOCUSED ULTRASOUND TRANSDUCER - An interchangeable transducer for use with an ultrasound medical system having a keyless adaptor and capable of operating in a wet environment. The interchangeable transducer has an adaptor for engaging a medical system, an ultrasound transducer and additional electronics to provide a self-contained insert for easy replacement and usage in a variety of medical applications. A slip ring spacer is also disclosed, the slip ring spacer for use with a pancake slip ring having a base and flange configuration to form one or more channels around each contact ring of the pancake slip ring. The channels provide fluid isolation around each connector to help reduce electronic cross talk and contact corrosion between the connector pads of the slip ring while the slip ring is immersed in a wet environment.10-02-2008
20130178764LARGE AREA BODY SHAPING APPLICATOR - A method and apparatus that affect vacuum to massage a volume of the skin and one or more types of skin treatment energies coupled to the massaged volume to treat the skin and subcutaneous adipose tissue and produce a desired treatment effect. The method and apparatus are based on coupling an array or a number of arrays being an assembly of skin treatment units with each skin treatment unit including a hollow cavity and a number of different energy to skin applying elements operative to receive skin treatment energy from a source of such energy and couple or apply the received energy to a treated segment of skin.07-11-2013
20130178765ULTRASOUND NEUROMODULATION OF SPINAL CORD - Methods and systems for non-invasive neuromodulation of the spinal cord utilize a transducer to deliver pulsed ultrasound energy to up regulate or down regulate neural targets for the treatment of pain and other disease conditions. The systems provide control of direction of the energy emission, intensity, frequency, pulse duration, pulse pattern, mechanical perturbation, and phase/intensity relationships to achieve up regulation and/or down regulation. One embodiment focuses an elongate tubular ultrasound beam which can be aligned with a target region of the spinal cord.07-11-2013
20080221490METHOD AND APPARATUS FOR REPAIR OF INTERVERTEBRAL DISCS - A method of repairing an intervertebral disc of a patient's body includes identifying a target area of the intervertebral disc. An ultrasound generator is placed proximate the target area and outside the patient's body. An area temperature at the target area is monitored. Ultrasonic energy is generated with the ultrasound generator within a predetermined energy range. The ultrasonic energy is adjusted in response to the area temperature exceeding a predetermined temperature range. An apparatus for repairing an intervertebral disc of a patient's body is also provided.09-11-2008
20080221489Personal sonic massage device and method - A personal massage system includes first and second audio transducers mounted in and coupled to a housing in a spaced-apart and opposing fashion. The first and second audio transducers are energized to produce corresponding first and second sonic waves that radiate towards one another and interact between the first and second audio transducers.09-11-2008
20120253239ENERGETIC MODULATION OF NERVES - A system for applying focused ultrasound energy to a nerve surrounding an artery of a patient includes a piezoelectric array comprising a plurality of piezoelectric elements, a controller configured to control at least a subset of the piezoelectric elements so that at least one of the piezoelectric elements in the subset is in a signal transmitting mode, in a signal sensing mode, or both, a first platform on which the piezoelectric elements are coupled and a second platform, wherein the second platform is configured to support at least a part of the patient, a programmable generator configured to generate output power for one or more of the piezoelectric elements, and a programmable processor configured to process a signal sensed by at least one of the piezoelectric elements.10-04-2012
20080214965Removable multi-channel applicator nozzle - The invention provides a multi-channel applicator nozzle.09-04-2008
20130096470ULTRASONIC MEDICAL DEVICE - An ultrasonic medical device can include a transducer, a coupling system, and a waveguide. The coupling system can be configured to attach and adequately torque the waveguide to the transducer for use in a medical procedure. The coupling system can be configured to detach the inner probe from the transducer upon completion of the medical procedure.04-18-2013
20130096468COUPLING FOR SLIP RING ASSEMBLY AND ULTRASONIC TRANSDUCER IN SURGICAL INSTRUMENT - An ultrasonic surgical instrument includes a body such as a handle assembly and an acoustic transmission assembly. The acoustic transmission assembly includes an ultrasonic transducer and an end effector. A mounting ring is positioned on a horn of the transducer. A rotatable drum is positioned distal to the mounting ring. Piezoelectric components of the transducer are positioned proximal to the mounting ring. Electrical conduits extend from the drum to the piezoelectric components and are routed over or through the mounting ring. The drum is coupled with a power source through a slip ring assembly to selectively activate the transducer.04-18-2013
20130096469ULTRASOUND NEUROMODULATION TREATMENT OF OBESITY AND EATING DISORDERS - Disclosed are methods and systems for non-invasive neuromodulation using ultrasound to treat obesity and eating disorders. The neuromodulation can produce acute or long-term effects. The latter occur through Long-Term Depression (LTD) and Long-Term Potentiation (LTP) via training. Included is control of direction of the energy emission, intensity, frequency, pulse duration, pulse pattern, and phase/intensity relationships to targeting and accomplishing up regulation and/or down regulation.04-18-2013
20130102932Imaging Feedback of Histotripsy Treatments with Ultrasound Transient Elastography - Methods and devices for imaging tissue elasticity change as a tool to provide feedback for histotripsy treatments. Tissue lesion elasticity was measured with ultrasound shear wave elastography, where a quasi-planar shear wave was induced by acoustic radiation force generated by the therapeutic array, and tracked with ultrasound imaging at 3000 frames per second. Based on the shear wave velocity calculated from the sequentially captured frames, the Young's modulus in the lesion area was reconstructed. Results showed that the lesions were clearly identified on the elasticity images as an area with decreased elasticity. Lesions produced by histotripsy can be detected with high sensitivity using shear wave elastography. Decrease in the tissue elasticity corresponds well with the morphological and histological change.04-25-2013
20130131558METHOD AND APPARATUS FOR PREVENTING LOCALIZED STASIS OF CEREBROSPINAL FLUID - A system and method for treating, inhibiting or ameliorating Alzheimer's disease in a patient, comprising one or more transducers operatively connected to a power source for radiating vibrational or acoustical energy to the maxilla of the patient, wherein the energy is sufficient to radiate through the paranasal sinuses of the patient to the base of the patient's skull to assist in cerebrospinal fluid clearance and inhibit localized stasis of cerebrospinal fluid in the brain.05-23-2013
20130131559Light And Massage Multi-Therapy Hairbrush - A hairbrush includes a control panel, an interior vibratory element for providing massage therapy and a plurality of LEDs carried by the brush head for providing light therapy at a preselected wavelength selected to be of benefit to the hair and/or scalp. In response to user control input mode selection, the light and massage multi-therapy hairbrush selectively provides phototherapy, massage therapy, and combined massage and phototherapies.05-23-2013
20130131557Selective Destruction of Cancer Cells via Tuned Ultrasound Resonance - Disclosed is a method to use tuned resonant frequency ultrasonic energy for treatment of cancer that selectively destroys neoplastic cells while leaving surrounding healthy tissue minimally affected.05-23-2013
20100280420SYSTEM AND METHOD FOR VARIABLE DEPTH ULTRASOUND TREATMENT - A non-invasive variable depth ultrasound treatment method and system comprises a variable depth transducer system configured for providing ultrasound treatment to a patient. An exemplary variable depth transducer system can comprise a transducer configured to provide treatment to more than one region of interest, such as between a deep treatment region of interest and a superficial region of interest, and/or a subcutaneous region of interest. The variable depth transducer can comprise a transduction element having a piezoelectrically active layer, matching layers and/or other materials for generating radiation or acoustical energy. The variable depth transducer may be configured to operate at moderate frequencies within the range from approximately 750 kHz to 20 MHz or more. In addition, the transduction element may be configured with a variable depth device comprising one or more materials configured to allow for control and focusing/defocusing of the acoustic energy to more than one region of interest.11-04-2010
20080208083System and method to counter material deposition on devices in the urinary tract - The invention relates to a device and method to counteract the deposition of material on devices that dwell in the urinary tract and which include an operably connected motion-inducing actuator. Counteracting material deposition includes impeding or preventing deposition as well as diminishing extant deposition. Deposition is counteracted by moving the device with the motion-inducing actuator; motion may include movement of the device with respect to its position within the urinary tract, as well as deformational or vibrational movement of the device. Embodiments of the device receive energy from a source either by physical or wireless connection. In some embodiments the motion-inducing actuator is integral with the structure of the device, in other embodiments the actuator is a separate structure. In still other embodiments, the device receives energy directly, without intervention of an actuator. In some of these latter embodiments, the device may include an energy focusing element.08-28-2008
20110213281METHOD AND APPARATUS FOR THE REMOVAL OF NON DESIRED BIOLOGICAL COMPONENTS FROM SURFACES OF EXTERNAL TISSUES - The present invention provides a method, device and system for the removal of non-desired biological components from external surfaces of tissues. This, in accordance with the invention, is achieved utilizing ultrasound device and ultrasound-derived mechanisms employed essentially externally to the external surfaces of tissues to be affected, and while keeping the said tissues intact with respect to the impact of the bulk of the affected ultrasound.09-01-2011
20110230796SYSTEM AND METHOD FOR TREATING A THERAPEUTIC SITE - A targeting catheter is used to locate an arteriotomy, such as is formed during a femoral artery catheterization procedure. The targeting catheter includes one or more targeting aids, such as an inflatable balloon or sensor (e.g., Doppler or temperature sensor), to locate the arteriotomy. The targeting aid may be positioned at the arteriotomy. An ultrasonic beacon on the catheter may then be located relative to a therapeutic ultrasonic applicator (e.g., by using acoustic time-of-flight) so that the focus of ultrasonic energy from the applicator can be aligned with the arteriotomy.09-22-2011
20110275963SYSTEMS AND METHODS FOR STIMULATING TISSUE USING FOCUSED ENERGY - The present invention generally relates to systems and methods for stimulating tissue using focused energy. In certain embodiments, the invention provides a system for stimulating tissue that includes a first energy source, a second energy source, and a focusing element that focuses at least the first or second energy source so that the first and second energy sources target the same region of tissue such that the combined effect stimulates the tissue.11-10-2011
20110275962ACOUSTICAL SWITCH AND CATHETER COMPRISING ACOUSTICAL SWITCH - The invention relates to an acoustical switch wherein the idea to the ultrasound propagation direction may be changes without moving the switch. The switch device comprises two sheets of acoustically transparent material. The sheets constitute opposite walls of a housing. The switch device further comprises one or more orifices for allowing conduction of fluid into and/or out of said housing. The switch device may be made reflective by filling the housing with a gas via the one or more orifices. Moreover, the switch device may be made transmissive to ultrasound by filling the housing with a liquid via the one or more orifices and/or by subjecting the housing to underpressure via the one or more orifices. The acoustical switch device fits well within a catheter, which has severe dimensional limitations.11-10-2011
20110237983ULTRASOUND CATHETER FOR DISRUPTING BLOOD VESSEL OBSTRUCTIONS - Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, an ultrasound catheter includes an elongate flexible catheter body with one or more lumens. An ultrasound transmission member or wire extends longitudinally through the catheter body lumen and, in many embodiments, a guide wire tube also extends through the same lumen. A distal head is fixed to or otherwise mechanically coupled with the distal end of the ultrasound transmission member or wire and is positioned adjacent the distal end of the catheter body. Although the distal end of the catheter body overlaps the distal head, the distal head is not directly affixed to the distal end of the catheter body. Thus, the distal tip may move freely, relative to the distal end of the catheter body when ultrasonic energy is applied through the ultrasound transmission member. Such a freely floating distal head enhances the efficiency of an ultrasound catheter, enabling the catheter to ablate calcific occlusions and increasing the useful life of the ultrasound transmission member and catheter.09-29-2011
20110237982Ultrasound-enhanced stenosis therapy - Apparatus and methods are disclosed for vein and arterial-venous fistulas stenosis and occlusion therapies, including enhancing permeability of the vessel wall using ultrasound energy and delivering a therapeutic agent into the vessel wall. Ultrasound energy may be delivered at frequencies less than 10 MHz and power less than 20 watts using transcutaneous techniques and endovascular methods. Therapeutic agents may be delivered to the treatment area via intravenous and endovascular methods. In some embodiments, ultrasound energy and therapeutic agent application may be combined with angioplasty techniques and with blood flow protection devices. In some other embodiments, a therapeutic agent may be removed from the body after exposure to the vessel wall to minimize a systemic effect of the therapeutic drug.09-29-2011
20110237981MEDICAL DEVICE AND METHOD FOR OPERATING A MEDICAL DEVICE - The application pertains to a medical device including a treatment unit for treating patients, an activation device for activating the treatment unit, and an input device for entering an activation code, the input device being coupled to the activation device, and the activation device is arranged to activate the treatment unit for a limited number of treatments and/or for a limited period when a predetermined activation code is entered via the input device.09-29-2011
20120277640ULTRASOUND COUPLING DEVICE - The present invention relates to an ultrasound coupling device for use with various ultrasound transducers, systems, and applications. The coupling device includes a coupling compartment comprising a chamber having a continuous side wall and an opening on a first end. The continuous side wall is configured to hold a low-profile ultrasound transducer within the chamber so that a front ultrasound emitting surface of the low-profile ultrasound transducer faces outward toward the chamber opening. The front ultrasound emitting surface is configured to control the direction and wave pattern of ultrasonic energy emitted from the transducer. The continuous side wall is also configured to hold a quantity of an ultrasound conductive medium within the chamber and is operative to keep the ultrasound conductive medium in simultaneous contact with a surface of a subject and with at least a portion of the front ultrasound emitting surface of the transducer. The present invention also relates to an ultrasound apparatus, kit, and methods of using the ultrasound coupling device, apparatus, and kit.11-01-2012
20130150756RIB IDENTIFICATION FOR TRANSCOSTAL FOCUSED ULTRASOUND SURGERY - A method for transcostal ultrasound treatment of tissues includes determining rib locations, e.g., based on ultrasound reflections off the ribs or acoustic radiation force signals, and transcostally focusing ultrasound into the tissue while minimizing damage to the ribs.06-13-2013
20120259249Noninvasive Ultrasound-Based Retinal Stimulator: Ultrasonic Eye - Focused ultrasound is a promising technology for neural stimulation that is non-invasive, and capable of passing through the skull. Here we use the isolated retina to characterize the effect of ultrasound on an intact neural circuit and compared these effects to those of visual stimulation of the same retinal ganglion cells. Ultrasound stimuli evoked precise, stable responses that looked qualitatively similar to strong visual responses but with shorter latency. We found that ultrasonic stimulation activates cells presynaptic to ganglion cells, which may include photoreceptors and interneurons. Ultrasonic stimulation is an effective and spatial-temporally precise method to activate the retina. Ultrasonic stimulation may have diagnostic potential to probe remaining retinal function in cases of photoreceptor degeneration, and therapeutic potential for use in a retinal prosthesis. In addition, ultrasound promises to be a useful tool to understand the dynamic activity in the interneuron population of the retina.10-11-2012
20100318003Method and Apparatus for Connective Tissue Treatment - The invention relates to methods and apparatus for therapeutically treating connective tissue or increasing vascularization in tissue using ultrasound. More particularly, the present invention relates to methods and apparatus which use ultrasound to stimulate growth or healing, or to treating pathologies, of connective tissue, or to increase vascularization in ischaemic or grafted tissue using ultrasound.12-16-2010
20100318002Acoustic-Feedback Power Control During Focused Ultrasound Delivery - Ultrasound energy is delivered to a patient in a controlled manner using a focused ultrasound system, thus maintaining the desired therapeutic effect without causing unwanted damage to surrounding tissue. An ultrasound transducer device includes multiple transducer elements, each of which is controlled by drive circuitry and a drive signal controller. An acoustic detector detects signals indicative of cavitation in tissue targeted by the transducer elements, and the drive signal controller manages the delivery of acoustic energy from the transducer elements based on the detected cavitation signals such that a therapeutic effect at the target tissue remains within an efficacy range.12-16-2010
20120283605PORTABLE ULTRASOUND SYSTEM - The present invention relates to a portable ultrasound system that can be used for a wide range of ultrasound applications. The portable ultrasound system includes an energy generating module operative to generate a driving signal that can be transformed into ultrasonic energy, where the energy generating module includes a power source, an oscillator, and a driver component. The portable ultrasound system also includes an ultrasound transducer having a piezoelectric component and a lens component. The ultrasound transducer is operative to receive the driving signal from the energy generating module, to transform the driving signal into ultrasonic energy, and to control the direction of the ultrasonic energy emitted from the ultrasound transducer. Also disclosed are devices containing the portable therapeutic ultrasound system of the present invention, as well as methods of using the system.11-08-2012
20120283604ULTRASOUND NEUROMODULATION TREATMENT OF MOVEMENT DISORDERS, INCLUDING MOTOR TREMOR, TOURETTE'S SYNDROME, AND EPILEPSY - Disclosed are methods and systems and methods for non-invasive neuromodulation using ultrasound to treat movement disorders (e.g., tremor disorders such as Parkinson's Disease and essential tremor, Tourette's Syndrome, and epilepsy). Also included are the Tourette's vocalizations. The neuromodulation can produce acute or long-term effects. The latter occur through Long-Term Depression (LTD) and Long-Term Potentiation (LTP) via training Included is control of direction of the energy emission, intensity, frequency, pulse duration, firing pattern, and phase/intensity relationships to targeting and accomplishing up regulation and/or down regulation.11-08-2012
20120283603Photonic and Thermal Kinetic Energy Therapeutic Device, System and Method - An apparatus includes a housing having a treatment surface, a light source disposed adjacent the treatment surface and configured to emit dynamic photonic energy, a thermal element disposed adjacent the treatment surface and configured to emit dynamic thermal kinetic energy, and a controller disposed in the housing, the controller in communication with the light source and the thermal element to vary a plurality of parameters of the light source and the thermal element to control the characteristics of the dynamic photonic energy and the dynamic thermal kinetic energy emitted thereby. The treatment surface can also house a variety of sensors that can capture a variety of physical and chemical data, which is integrated with a malleable energy composition and delivery system that co-ordinates with the treatment progress.11-08-2012
20130158440TREATMENT PLANNING SYSTEMS AND METHODS FOR BODY CONTOURING APPLICATION - Methods and system for treatment planning for non- and minimally-invasive alteration of body adipose tissue for reduction and contouring of body fat are described herein. Treatment plans can be generated by capturing current body part data (e.g., positioning, contour/shape, thickness of adipose tissue, etc.), determining desired outcome of treatment (e.g., percent reduction of adipose tissue thickness, degree of contour change, etc.), and determining treatment parameters to achieve desired results. Algorithms can be used to determine best-fit treatment parameters to use in treatment sessions. In some embodiments, the system can provide a predictive end-result image for communication to patient and/or for determining alteration of desired outcome. In various embodiments, real-time monitoring of feedback data can be used to determine treatment plan efficacy. Additional algorithms can provide real-time comparison of feedback data to anticipated feedback data, and can be used to change treatment parameters in real-time to achieve desired effects.06-20-2013
20130184614NON-INVASIVE TREATMENT OF FASCIA - Various methods and devices for minimally invasive treatment and prevention of conditions of the fascia are provided. In one aspect, a method includes providing an acoustic wave source effective to deliver a focused acoustic wave to a target site within a patient's body, and focusing an acoustic wave through a patient's skin such that at least one location in the patient's fascia is fenestrated in a desired pattern.07-18-2013
20110282251Methods and Systems for Delivery of Acoustic Energy to Tissue Surfaces, Cavities and Obstructed Passages such as Intranasal Ostia - Methods and systems for delivering fluids, aerosols, and/or acoustic energy to target sites on tissue surfaces and within body cavities or lumens, obstructions or undesired materials associated with body cavities and tissue surfaces and, particularly, target sites on tissue surfaces or at obstructions within natural orifices, such as ear, nose and throat passages and, particularly, nasal passages and cavities, are provided. Delivery of acoustic energy may be accomplished using a flexible, expandable member adapted to be expanded at a target site using an acoustically transmissive material for delivery of acoustic energy to tissue surfaces in irregularly configured tissue cavities and passageways.11-17-2011
20110282250METHODS AND DEVICES FOR TREATING ATRIAL FIBRILLATION - Described here are systems and methods for affecting tissue within a body to form a lesion. Some systems comprise tissue-affecting devices, devices that guide the advancement of the tissue-affecting elements to a target tissue region, devices that locate and secure tissue, and devices that help position the tissue-affecting devices along the target tissue. The methods described here comprise advancing a first tissue-affecting device to a first surface of a target tissue, advancing a second tissue-affecting device to a second surface of the target tissue, and positioning the first and second devices so that a lesion may be formed in the tissue between them. In some variations, the devices, systems, and methods described here are used to treat atrial fibrillation by ablating fibrillating tissue from an endocardial surface and an epicardial surface of a heart. Methods of closing, occluding, and/or removing the left atrial appendage are also described.11-17-2011
20130123670DEVICE AND METHODS FOR RENAL NERVE MODULATION - Systems for nerve modulation are disclosed. An example system may include a first elongate element having a distal end and a proximal end and having at least one nerve modulation element disposed adjacent the distal end. The nerve modulation element may be an ultrasound transducer. Activation of the nerve modulation element may ablate multiple regions of a target area.05-16-2013
20110313328Methods and apparatus for dissolving blockages in intracranial catheters - Methods for removing blockages from intracranial drainage catheters caused by cerebrospinal fluid or blood clots using ultrasound energy are provided. These blockages may be caused by cerebrospinal fluid or blood clots located inside or outside of the drainage catheter. One or more pharmacologic agents may be delivered to the treatment area to further facilitate the dissolving and removal of blockages.12-22-2011
20130190659METHOD AND SYSTEM FOR ULTRASOUND TREATMENT OF FAT - A method and system for providing ultrasound treatment to a tissue that contains a lower part of dermis and proximal protrusions of fat lobuli into the dermis. An embodiment delivers ultrasound energy to the region creating a thermal injury and coagulating the proximal protrusions of fat lobuli, thereby eliminating the fat protrusions into the dermis. An embodiment can also include ultrasound imaging configurations using the same or a separate probe before, after or during the treatment. In addition various therapeutic levels of ultrasound can be used to increase the speed at which fat metabolizes. Additionally the mechanical action of ultrasound physically breaks fat cell clusters and stretches the fibrous bonds. Mechanical action will also enhance lymphatic drainage, stimulating the evacuation of fat decay products.07-25-2013
20130190660SURGICAL OPERATION SYSTEM - A surgical operation system includes a US signal output section, an HV signal output section, a probe having a treatment section which has an HV signal applied thereto and vibrates by ultrasound, an HV signal main control section that performs feedback control of the HV signal output section based on the HV signal, a US signal main control section that performs feedback control of the US signal output section based on a US signal, and an HV signal auxiliary control section that controls the HV signal output section based on the US signal, and has a response time shorter than that of the HV signal main control section.07-25-2013
20110319793THERMAL THERAPY APPARATUS AND METHOD USING FOCUSED ULTRASONIC SOUND FIELDS - Apparatus and method for delivering increased amounts of energy to localized treatment zones in a target tissue volume are provided. In some instances the non-linear wave propagation and other properties of the treatment apparatus and propagation medium as well as novel beam forming and control of the treatment apparatus are employed to generate extended focal zones for efficient treatment of a condition in a patient.12-29-2011
20120029397TUMOR TREATMENT USING ULTRASOUND CAVITATION - Growth in body tissue is slowed, arrested or reversed. In one aspect, this is accomplished by providing bubbles (S02-02-2012
20120029396MOTION COMPENSATION FOR NON-INVASIVE TREATMENT THERAPIES - Treatment of moving tissue may be facilitated by identifying voxels within a volume of the tissue, associating treatment-related attributes with the voxels, and shifting positions of the voxels based on the tissue movement. One or more treatment parameters may then be altered based on the treatment-related attributes of the shifted voxels.02-02-2012
20120029395ULTRASOUND OPERATION SYSTEM AND SURGICAL TREATMENT INSTRUMENT - An ultrasound operation system includes an output transformer, a hand piece including an object to be driven including an ultrasound transducer which is driven by the output transformer and a treatment portion which is connected to the ultrasound transducer to perform treatment of a living tissue by an ultrasound vibration generated in the ultrasound transducer, and an amplitude regulating portion which is provided between the output transformer and the object to be driven, and perform regulation of an amplitude of the ultrasound transducer by diverting a current which flows into the ultrasound transducer from the output transformer in accordance with a state of a load exerted on the treatment portion and regulating an amount of a current which flows into the ultrasound transducer.02-02-2012
20120029394Ultrasound Assisted Laser Skin and Tissue Treatment - The present invention relates to an ultrasound assisted medical laser for the therapeutic and cosmetic treatment of a patient's skin and underlying adipose tissue and more particularly, to apparatuses and methods using combinations of ultrasound, lasers and cryogenic energy to rejuvenate and condition skin and related tissue. The device of the present invention comprises a laser generator, an ultrasound generator, an ultrasound transducer, a handpiece containing a transducer tip at the distal end of the ultrasound transducer, and a laser tip. Ultrasonic and light radiation is directed into the tissue being treated. A cryogenic solution is circulated through the ultrasound tip to transfer thermal energy away from the tissue to preserve the tissue being treated by providing a synergistic effect with the ultrasonic radiation and light radiation.02-02-2012
20120029393COMPACT ULTRASOUND TRANSDUCER ASSEMBLY AND METHODS OF MAKING AND USING THE SAME - A compact ultrasound transducer assembly is provided. The ultrasound transducer assembly comprises a compact housing, a therapy transducer disposed in the compact housing, and an interchangeable Fresnel lens having a flat surface and a structured surface. The Fresnel lens is disposed in the compact housing so that the flat surface of the Fresnel lens faces the therapy transducer. The structured surface of the Fresnel lens is disposed in a direction away from the therapy transducer, and the Fresnel lens is removably coupled to the therapy transducer, the compact housing, or both.02-02-2012
20130197400System and method for determining the optimum size of an ultrasonic wave generation device - The present invention relates to a method for determining a probe model for treating an eye pathology, from among a plurality of different probe models, each probe including a cone-shaped ring including a proximal end (08-01-2013
20130197401OPTIMIZATION OF ULTRASOUND WAVEFORM CHARACTERISTICS FOR TRANSCRANIAL ULTRASOUND NEUROMODULATION - The present invention relates to methods and systems for achieving effective neuromodulation by transcranial ultrasound (bioTU). Embodiments of the invention include methods and systems for selecting, generating, and delivering transcranial ultrasound to the brain of a living subject. Methods and systems are described for determining the effect of bioTU on brain function. Certain embodiments of the present invention include methods and systems for measuring at least one quantifiable metric of brain activity, cognitive function, or physiology in order to optimize the ultrasound waveforms delivered. In an embodiment, the invention uses a closed-loop design to iteratively improve the effectiveness of bioTU waveforms delivered.08-01-2013
20120296238System and Methods for Energy-Based Sealing of Tissue with Optical Feedback - An energy-based tissue-sealing system and method provide higher sealing quality by measuring and using optical feedback parameters that are directly correlated to structural changes of tissue. The tissue-sealing system includes a sealing energy source, an instrument having a mechanism for grasping and deforming the tissue and for delivering sealing energy to the tissue, a light source, optical sensors, and a controller for controlling parameters of the sealing energy generated by the sealing energy source based upon the optical parameters of the tissue structure sensed by the optical sensors. At the beginning of a sealing procedure, the controller may monitor an initial optical parameter of the tissue and select a target trajectory of tissue optical parameters based on the initial optical parameter. During the sealing procedure, the controller monitors at least one optical parameter of the tissue structure and controls at least one parameter of the sealing energy based on the at least one optical parameter.11-22-2012
20130204166CUSTOM DESIGNED MICROBUBBLE CONTRAST AGENTS AND TECHNIQUES OF ULTRASOUND DELIVERY OPTIMIZED FOR GENE THERAPY - The invention pertains to a lipid-based microbubble stably binding a plurality of nucleic acids, and a method of delivering the microbubble and nucleic acids to a specific target site using ultrasound. The delivered nucleic acids create transgenic cells (i.e., for example, a transgenic tumor cell), wherein the transgenic cell expresses the proteins encoded by the delivered nucleic acids. This technology provides a significant improvement for microbubble-drug delivery platforms as known microbubble do not efficiently bind nucleic acids. The improvements described herein include but are not limited to identifying proper lipid proportionality ratios and/or cationic surfactant layers that provide an optimum mechanical index compatible with ultrasonics. Microbubble perfusion and/or nucleic acid delivery may be performed by a combination of imaging and ultrasound/microbubble targeted delivery to simultaneously perform low power two-dimensional imaging and high power microbubble destruction. Such systems are useful in therapeutics and/or diagnostics. For example, the data disclosed herein shows proof of principle in conjunction with the delivery of therapeutic siRNA molecules to slow tumor growth.08-08-2013
20120065552Macro/Micro Duty Cycle Devices, Systems, and Methods Employing Low-Frequency Ultrasound or Other Cyclical Pressure Energies - Improved devices, systems, and methods treatment of patients can be used to help mitigate injury to the kidneys by applying cyclical mechanical pressure energy at low intensities. The energy often be selectively directed from non-invasive transducers disposed outside the patients. The energy will typically comprise low frequency ultrasound energy, shock wave energy, or the like, and may induce the generation and/or release of nitric oxide, thereby enhancing perfusion and ameliorating tissue damage. Superimposed micro and macro duty cycles may help avoid thermal and other injury to tissues of the patient during treatment. Bilateral treatments are facilitated by a support structure that orients at least one transducer toward each kidney.03-15-2012
20120095372ULTRASOUND TRANSDUCER - There is provided in accordance with an exemplary embodiment of the invention an ultrasound transducer for intrabody medical therapy comprising; an element adapted to transmit ultrasound energy; at least two electrodes configured to apply a voltage across at least some volume of the element; and a gas bubble containment area adapted to retain the gas bubble when in blood.04-19-2012
20120095371ULTRASOUND TRANSDUCER AND COOLING THEREOF - An ultrasonic transducer device for producing ultrasonic beams comprises a body vibratable at ultrasonic frequencies and an extensive surface for beam emanation, the device configured to produce an unfocused, or alternatively a focused, power beam for tissue ablation, the power beam being produced by vibration over the body of the transducer and emanating from the extent of the surface, whereby the extensive surface becomes subject to convective cooling when immersed in a fluid by a chimney effect set up by said unfocused beam.04-19-2012

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