| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 600008000 | Seeds | 34 |
| 20090275793 | BRACHYTHERAPY DEVICES AND RELATED METHODS AND COMPUTER PROGRAM PRODUCTS - Methods of forming a low-dose-rate (LDR) brachytherapy device include depositing a solution comprising a soluble form of a radioactive material on a substrate. A water-insoluble form of the radioactive material is formed on the substrate by chemical precipitation and/or thermal decomposition. | 11-05-2009 |
| 20130035537 | ROBOTIC SYSTEMS AND METHODS FOR TREATING TISSUE - A method of manipulating an elongate member in at least two degrees of freedom includes holding an elongate member between two rotary members that define respective rotational axes, the elongate member having a flexible proximal portion, a distal rigid needle attached to the proximal portion, and an operative element for delivering energy, the needle having a distal port, actuating at least one of the rotary members in a rotational direction about its rotational axis to generate a corresponding linear motion of the elongate member along a longitudinal axis of the elongate member, and actuating at least one of the rotary members in a linear direction along its rotational axis to generate a corresponding rotational motion of the elongate member about the longitudinal axis of the elongate member. | 02-07-2013 |
| 20130046128 | Radiotherapy Delivery Cannula With Visual Confirmation Window - A radiotherapy delivery device is provided comprising an elongated applicator having a proximal end and a distal end having a tip. The distal end is adapted to be introduced into a body including a treatment zone to be located adjacent a target tissue. A radiotherapy emitter is provided that is moveable between the proximal end of the applicator and the treatment zone of the applicator. The applicator includes a window to permit visual confirmation of the location of the radiation emitter and the treatment zone. | 02-21-2013 |
| 20130102832 | BRACHYTHERAPY DEVICES AND RELATED METHODS HAVING MICROENCAPSULATED BRACHYTHERAPY MATERIALS - A brachytherapy device includes a bioabsorbable support and a plurality of microcapsules on the support. Each of the plurality of the microcapsules includes a plurality of microspheres and a bioabsorbable microcapsule wall that encloses the plurality of microspheres. The plurality of microspheres includes radiation-emitting microspheres comprising a radioactive material, radio-opaque microspheres comprising a radio-opaque material or a combination thereof. | 04-25-2013 |
| 20130131434 | DOSIMETRICALLY CUSTOMIZABLE BRACHYTHERAPY CARRIERS AND METHODS THEREOF IN THE TREATMENT OF TUMORS - Brachytherapy radioisotope carrier systems and methodology for providing real-time customized brachytherapy treatment to subjects with tumors difficult to control using conventional radiation therapy techniques. The invention generally relates to devices, methods and kits for providing customized radionuclide treatments, to help cure, slow progression or regrowth, or ameliorate the symptoms associated with tumors. | 05-23-2013 |
| 20120016176 | IMPLANTS FOR USE IN BRACHYTHERAPY AND OTHER RADIATION THERAPY THAT RESIST MIGRATION AND ROTATION - A therapeutic strand implant, for use in brachytherapy and deliverable to an implant site by way of a needle, includes a plurality of radioactive sources, and a polymeric material molded to encapsulate the radioactive sources. A space is defined by the polymeric material between each adjacent pair of the radioactive sources. A plurality of protrusions is defined by an outer surface of the encapsulating polymeric material. | 01-19-2012 |
| 20120108882 | Brachytherapy Devices and Related Methods Providing Bioaborbability and/or Asymmetric Irradiation - A brachytherapy device includes a sealed housing having a radioactive material therein, and at least one shielding member extending away from the housing and configured to provide radiation shielding on at least one side of the housing. | 05-03-2012 |
| 20100099940 | Thulium-containing low dose rate brachytherapy seed - A low dose rate brachytherapy seed having activity in the range between 0.5 and 10 millicurie, preferably less than 3 millicurie, comprising thulium-170 placed within a casing and at least one layer of a radiation emission modifying metal, said layer being provided either internally within the casing or on the outer surface thereof. The radiation emission modifying metal is preferably gold. | 04-22-2010 |
| 20090099402 | IMPLANTS FOR USE IN BRACHYTHERAPY AND OTHER RADIATION THERAPY THAT RESIST MIGRATION AND ROTATION - In an embodiment a therapeutic member includes a solitary radioactive seed. The seed includes a metallic housing with radioactive material contained within the metallic housing. The metallic housing has a first longitudinal end and a second longitudinal end and a longitudinal length between the first and second longitudinal ends. A polymeric material is molded to completely and monolithically encapsulate the metallic housing of the solitary radioactive seed. The implantable therapeutic member is adapted to be implanted into patient tissue using a hollow needle. A portion of the molded polymeric material extends from one of the first and second longitudinal ends of the metallic housing to reduce a tendency of the seed to migrate and rotate within a patient's body after implantation of the member. The portion of the molded polymeric material, that extends from one of the first and second longitudinal ends of the metallic housing, causes the implantable therapeutic member to have a longitudinal length that is greater than the longitudinal length of the metallic housing. | 04-16-2009 |
| 20090264696 | EXPANDABLE BRACHYTHERAPY DEVICE - A brachytherapy device for the provision of brachytherapy is disclosed. The brachytherapy device has at least one source lumen located outside a movable surface of the device. The source lumen may be secured to the movable outer surface in a manner whereby relative movement of the source lumen relative to the movable outer surface is permitted. The brachytherapy device is inserted into a body cavity. After insertion, the movable surface is moved to position the at least one source lumen closer to the tissue boundary of the cavity. One or more sources of radiation are then placed within the at least one source lumen to provide a customizable treatment. Also disclosed are methods for providing brachytherapy via body cavities. | 10-22-2009 |
| 20080234532 | FIDUCIAL MARKER - A fiducial marker which is visible to a wide range of imaging techniques, comprises a radiopaque material, such as barium sulphate or a metal wire, encapsulated in a biocompatible polymeric material, for example a polyaryletherketone such as polyetheretherketone. | 09-25-2008 |
| 20090203953 | THERAPEUTIC MEMBER INCLUDING A RAIL TO RESIST MOVEMENT WITHIN A NEEDLE USED IN BRACHYTHERAPY AND OTHER RADIATION THERAPY - A therapeutic member for use in brachytherapy deliverable to an implant site by way of a needle comprises a single radioactive source encapsulated by a bio-absorbable material having an outer surface including one or more ribs encircling the single radioactive source, a leading edge endcap rib and a trailing edge endcap rib. The one or more ribs reduces a tendency of the member to migrate and rotate within a patient's body after implantation. The encapsulating material further includes a first rail formed from the bio-absorbable material extending at least from opposite sides of the outer surface of the encapsulating material along the longitudinal axis of the therapeutic member, and a second rail formed from the bio-absorbable material extending at least from opposite sides of the outer surface of the encapsulating material along the longitudinal axis of the therapeutic member, the second rail arranged in a plane substantially perpendicular to a plane in which the first rail is arranged. | 08-13-2009 |
| 20090149692 | IMPLANTS FOR USE IN BRACHYTHERAPY AND OTHER RADIATION THERAPY THAT RESIST MIGRATION AND ROTATION - In an embodiment a therapeutic member includes a single radioactive seed and is adapted to be implanted into patient tissue using a hollow needle. The seed includes a metallic housing with radioactive material contained within the metallic housing. A polymeric bio-adherent and/or bio-adhesive material surrounds at least a portion the housing of the single radioactive seed. The polymeric bio-adherent and/or bio-adhesive material reduces a tendency of the member to migrate and rotate within a patient's body after implantation of the member. | 06-11-2009 |
| 20100261946 | FLEXIBLE AND/OR ELASTIC BRACHYTHERAPY SEED OR STRAND - A flexible or elastic brachytherapy strand that includes an imaging marker and/or a therapeutic, diagnostic or prophylactic agent such as a drug in a biocompatible carrier that can be delivered to a subject upon implantation into the subject through the bore of a brachytherapy implantation needle has been developed. Strands can be formed as chains or continuous arrays of seeds up to 50 centimeters or more, with or without spacer material, flaccid, rigid, or flexible. | 10-14-2010 |
| 20120142993 | Method for large scale production of cesium-131 with low cesium-132 content - The present invention provides a method for large scale production of cesium-131 (Cs-131) with low cesium-132 (Cs-132) content, where the Cs-131 is produced via barium-131 (Ba-131) decay. Uses of the Cs-131 produced by the method include cancer research and treatment, such as for use in brachytherapy. Cesium-131 is particularly useful in the treatment of faster growing tumors. | 06-07-2012 |
| 20110054235 | PACKAGING SYSTEM FOR BRACHYTHERAPY IMPLANT AND CUTTING THEREOF - The present disclosure relates to a thermo formed tray having an upper half and a lower half. The upper half and the lower half define a closed configuration when the upper half and the lower half are substantially adjacent one another and an open configuration when the upper half and the lower half are substantially apart from one another. A predetermined area is provided in at least one of the upper half and the lower half for containing a product in the closed configuration, the product having at least one radioactive seed held in a predetermined seed configuration. At least one cutter guide is contained in the thermo formed tray. | 03-03-2011 |
| 20100056844 | BRACHYTHERAPY SEED WITH FAST DISSOLVING MATRIX FOR OPTIMAL DELIVERY OF RADIONUCLIDES TO CANCER TISSUE - A system, method and device for treating tumor cells utilizing a resorbable therapy seed made up of microspheres containing a beta- or alpha-particle-emitting radiation source and a resorbable polymer matrix. These seeds are implanted within the tumor and then rapidly dissolved so as to release the microspheres from the polymer matrix. These microspheres then spread within a preselected target area and provide radiation therapy in a predetermined amount and at a preselected rate according the specific needs and necessities of the users. The configuration of the microspheres, the types of radiation provided and the location and use of these microspheres provides desired localized treatment to target cells while preferentially avoiding or minimizing undesired damage to surrounding tissue. The present invention provides a method for making the seeds, as well as a method for utilizing the seeds as a part of the treatment method. | 03-04-2010 |
| 20090216065 | Radiation Containing Seeds and Method for High Visibility Magnetic Imaging - A radioactive seed and method for making a radioactive seed with selective magnetic imaging characteristics are provided. The seed comprises a housing which may include a metal shell for at least partially enclosing a radioactive material. The shell encloses a rod having a nickel layer with a phosphorous content, wherein the phosphorous content comprises a level of phosphorous sufficient, when the seed is implanted in tissue, to provide a defined magnetic resonance signature of the seed while substantially eliminating gross artifacts in the magnetic resonance image. | 08-27-2009 |
| 20090247807 | RADIOTHERAPY DEVICE AND METHOD - A radioactive implant for brachytherapy includes a composite radioactive source having at least two different types of radionuclides. | 10-01-2009 |
| 20080287729 | INTERSTITIAL MARKER AND METHOD FOR CREATION THEREOF - An interstitial marker for localization of organs, biopsy sites, tumors or tumor beds, is comprised of a fluid marker material which is visible under at least one imaging modality. The fluid marker material is injected at the desired location to create a marker having a desired size and configuration. The configuration includes combinations of straight and curved lines, spheres and blank spaces. The fluid marker material includes a high density metal such as bismuth, gold, or iridium suspended in a liquid, in colloidal form or made into a solution. | 11-20-2008 |
| 20110118532 | Brachytherapy seed - A radiopaque brachytherapy seed for implantation into a subject includes a biocompatible component, a therapeutically active component including a non-radioactive drug, and a radiopaque marker. The biocompatible component is (a) physically associated with a therapeutically active component and (b) in contact with the radiopaque marker. The brachytherapy seed has a size and shape suitable for passing through the bore of a needle having an interior diameter of less than about 2.7 millimeters (10 gauge). | 05-19-2011 |
| 20100324353 | ADHESIVE-STIFFENED BRACHYTHERAPY STRAND - A stranded brachytherapy product and methods of forming a stranded brachytherapy product. The methods includes the step of applying an adhesive to a carrier containing at least one brachytherapy seed so as to, upon curing of the adhesive, impart substantial rigidity to the carrier. Alternatively, the adhesive may be selectively applied so as to provide a deflectable brachytherapy product. | 12-23-2010 |
| 20100121130 | DELIVERY SYSTEM AND METHOD FOR INTERSTITIAL RADIATION THERAPY - A prescription method of treating tissue comprises the steps of accepting a prescription tissue treatment plan for the tissue to be treated, positioning seeds relative to each other per the prescription tissue treatment plan such that the positions of seeds relative to each other is only established by the prescription tissue treatment plan, and creating a treatment strand by heating and cooling a material to position the plurality of treatment seeds in the material. The prescription tissue treatment plan specifies a number and a spacing of the seeds to be provided in the treatment strand, the spacing of the treatment seeds being unrestricted by any use of spacers and independently set by and according to the prescription tissue treatment plan. | 05-13-2010 |
| 20100056843 | Brachytherapy Seed With Fast Dissolving Matrix for Optimal Delivery of Radionuclides To Cancer Tissue - A system, method and device for treating tumor cells utilizing a resorbable therapy seed made up of microspheres containing a beta-particle-emitting radiation source and a resorbable polymer matrix. These seeds are implanted within the tumor and then rapidly dissolved or broken so as to release the microspheres. These microspheres then spread within a preselected target area and provide radiation therapy in a predetermined amount and at a preselected rate according the specific needs and necessities of the users. The configuration of the microspheres, the types of radiation provided and the location and use of these microspheres provides desired localized treatment to target cells while preferentially avoiding undesired damage to surrounding tissue. The present invention provides a method for making the seeds, as well as a method for utilizing the seeds as a part of the treatment method. | 03-04-2010 |
| 20110166410 | METHOD AND SYSTEM FOR BRACHYTHERAPY - A brachytherapy system for a target region ( | 07-07-2011 |
| 20120065454 | TETHERED AND/OR VISUALLY CODED BRACHYTHERAPY DEVICES AND RELATED METHODS - Bracytherapy devices include a respective tether attached to a proximal end portion of the strands. The tether can be color-coded to match a color associated with the corresponding strand. | 03-15-2012 |
| 20120123189 | ONCOLOGY THERAPIES EMPLOYING RADIOACTIVE SEEDS - An oncology therapy method comprises implanting a radioactive seed ( | 05-17-2012 |
| 20090131735 | Implant Comprising Radioactive Seeds - The present disclosure relates to an implant comprising at least two sheets of a biocompatible material, and at least one radioactive seed disposed between said sheets of material. The disclosure also relates to a method for treating a patient, comprising fixing to the tissue of the patient at least one implant comprising at least two sheets of a biocompatible material, and at least one radioactive seed disposed between said sheets of material. | 05-21-2009 |
| 20090131734 | Implantable medical marker and methods of preparation thereof - An implantable medical marker, the marker comprising a marker body adapted for insertion via a needle and adapted to define a volume with a smallest dimension larger than an inner diameter of the needle; and a radiation source—characterized by gamma emissions sufficient to exit the human body. | 05-21-2009 |
| 20120253100 | BRACED BRACHYTHERAPY NEEDLE - Braces to reduce bending of a brachytherapy needle during insertion into a patient, as well as methods of using the needle braces and kits useful therefor. | 10-04-2012 |
| 20100298622 | APPARATUSES AND TECHNIQUES FOR BIOACTIVE DRUG DELIVERY IN THE PROSTATE GLAND - Methods and apparatuses for the delivery of bioactive substances into the prostate. The present invention encompasses the release of bioactive substances into the prostate of a patient. Preferably, the present invention employs either a sustained-release or depot formulation of the bioactive substance to release the substance over an extended period of time. In particularly-preferred embodiments, the apparatuses of the present invention release of anti-inflammatory agents into the prostate. The anti-inflammatory agents preferably reduce the inflammation that is associated with brachytherapy and other conditions of the prostate. In particular, corticosteroid anti-inflammatory agents are employed in the context of the present invention. | 11-25-2010 |
| 20120259153 | DELIVERY SYSTEMS FOR BRACHYTHERAPY, AND ASSOCIATED METHODS - Delivery systems adapted for implementation during a brachytherapy procedure are provided. The delivery system includes a plurality of brachytherapy seeds and a plurality of spacers. Each spacer is formed of a matrix material carrying a plurality of microparticles and/or nanoparticles. The microparticles and/or nanoparticles carry an agent and are biodegradable and/or biocompatible. The brachytherapy seeds and the spacers are configured to be delivered to a target site. Associated methods are also provided. | 10-11-2012 |
| 20090318746 | Lubricious echogenic coatings - Medical devices can include a lubricious echogenic coating that is slippery when wet and provides visibility during ultrasonic imaging. | 12-24-2009 |
| 20120277519 | Apparatus and Method to shield Radiation Needles - According to one general aspect there is a needle package apparatus that comprises a top portion and a bottom portion; a plurality of needle slots exact distance apart that allows to place a plurality of needles that contain radioactive seeds; a cylindrical coil that is inserted to the plurality of needle slots to hold said plurality of needles, wherein said cylindrical coil prevents the leakage of the radiation from the radioactive seeds; a set of hinges located at the end of said needle package within the outer most said plurality of needle slots; wherein the hinges can be bend to change the angle of said top portion of said needle package by a medical personnel to create a stand; and a single end enclosure located at the distal end of said cylindrical coil to provide an enclosed cylinder. | 11-01-2012 |
