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Detecting brain electric signal

Subclass of:

600 - Surgery

600300000 - DIAGNOSTIC TESTING

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Class / Patent application numberDescriptionNumber of patent applications / Date published
600545000 With feedback of signal to patient 47
Entries
DocumentTitleDate
20110178422INTRACEREBRAL INFORMATION MEASURING DEVICE - An intracerebral information measuring device which can be mounted on the head of a subject by simple surgery and which attains measurement of low invasion, high sensitivity, and high resolution is provided. An internally mounted unit is composed of a probe to be inserted in the brain through a hole having a small diameter bored in the skull of the subject, and a head section integrated with the probe section and to be disposed between the skull and the scalp. The probe section includes an electrode for sensing an action potential. The head section includes a transmitter for wirelessly transmitting signals captured with the electrode to the outside. On the outside of the head, an external measuring unit for receiving the signal transmitted from the head section and reproducing the original signal is provided.07-21-2011
20110184306DEVICE FOR TREATING PARKINSON'S DISEASE AND METHODS OF USE THEREOF - The invention includes a recordation and stimulation system for determining and delivering an electrical stimulation treatment based upon the current status of neuronal activity of a subject. The system include components for detecting neuronal activity in a subject's brain and, based upon the information received, determine an appropriate electrical stimulation treatment for the subject. The system allows immediate adjustments to the stimulation treatment as the needs of the subject change over time. The invention also includes a method for determining whether a subject has early Parkinson's Disease or advanced Parkinson's Disease. The method includes the steps of acquiring information regarding neuronal discharges in certain areas of the brain, creating a ratio based upon the neuronal activity, and determining whether a previous medical diagnosis of Parkinson's Disease is accurate.07-28-2011
20100145217SCALP POTENTIAL MEASURING METHOD AND APPARATUS - An apparatus for measuring scalp potential is disclosed, which comprises a plurality of sensors and a pre-amplifier coupled to these sensors. The sensors are adapted to measure a raw scalp potential measurement though a hair and air interface, and may be considered as a difference, reference or common measurement. The interface presents a high and variable source impedance coupling to the scalp. The pre-amplifier is adapted to have an input impedance significantly higher than that presented by the source interface, and receives the raw scalp potential measurement to produce a pre-amplified scalp potential measurement.06-10-2010
20090264788Nursing System of Visual Evoked Brain Wave Control Device - A nursing system of a visual evoked brain wave control device, measuring a brain wave signal induced by the user when gazing at one optical display region, for controlling external devices is designed. The optical flash generating device receives an outer signal to flash the optical display region therein. A brain wave signal measurement device is used to measure a brain wave signal induced by users when gazing at the optical display region. A programmable chip is used to analyze the relation between the brain wave signal and the optical flash generating device, and control a selected option of the optical display region gazed by the users (for example, raising/falling of first, second or third portion of the hospital bed, volume adjustment of radio, channel adjustment, etc.), for improving the independence capability and the life quality of the users.10-22-2009
20100076334ALZHEIMER'S COGNITIVE ENABLER - A computing device that enables user interaction when the user is in a mentally debilitating state includes a memory configured to store electroencephalogram (EEG) waveform signals. The EEG waveform signals are generated by associated recognition data. Response data is generated based on the associated recognition data and stored in memory. An input component is configured to receive an EEG waveform signal from a user. A processor is configured to compare the received EEG waveform signal with the stored EEG waveform signals to determine if the received EEG waveform signal matches a stored EEG waveform signal. An output component is configured to automatically output the response data generated by the associated recognition data based on the determination from the processor.03-25-2010
20120245481Method for automatic, unsupervised classification of high-frequency oscillations in physiological recordings - Oscillatory signals may be used to determine a region of a patient's body that is associated with a medical condition. As described herein, oscillatory signals may be detected using a high sensitivity, low specificity detector. The oscillatory signals may be representative of discrete events in a patient's body. The detected signals may be tested in the context of surrounding background activity to identify anomalous discrete physiologic events that are sufficiently different from the surrounding background activity. The anomalous discrete physiologic events having correlative morphological, time, or location characteristics may be automatically clustered and clusters of anomalous physiologic events may be determined that are indicative of at least one region of the patient's body that is associated with a medical condition.09-27-2012
20130079659INTEGRATION OF ELECTROENCEPHALOGRAPHY (EEG) AND TRANSCRANIAL DIRECT CURRENT STIMULATION (tDCS) WITH HIGH-SPEED OPERATION, ELECTRODE, RE-USE, AUTOMATED tDCS ELECTRODE CONFIGURATION, AND MULTIPLE INDEPENDENT tDCS CURENT SOURCES - Transcranial direct current stimulation (tDCS) and electroencephalography (EEG) are integrated, including re-using electrodes to perform both tDCS and EEG, and automatically alternating EEG collection and tDCS application. EEG and tDCS functionalities are integrated into a single headset. Improvements in tDCS include realizing multiple tDCS current flow configurations without repositioning electrodes, and concurrently applying multiple independent tDCS currents to a subject.03-28-2013
20090292221EEG Feedback Controlled Sound Therapy for Tinnitus - An automated method for treating tinnitus by habituation through use of neurological feedback, comprising the steps of connecting a subject through a set of attached headphones to an electronic sound player that is connected to a PC workstation presenting sound examples by software to the subject who can refine them by manipulating a series of controllers on the player, making an electronic recording of the sound in a digital music format, storing the recording in the computer, transferring a copy of the electronic sound file to the subject's electronic music player, generating an EEC signature of the subject's brain activity in response to the presented sound, sound using the customized sound to stimulate the auditory system while the brain activity is recorded, wherein the computer continuously monitors for the feedback signatures and drives the sound stimuli appropriately.11-26-2009
20100042011Three-dimensional localization, display, recording, and analysis of electrical activity in the cerebral cortex - The present invention describes a method and apparatus to localize the electrical signals measured from a subject's scalp surface, preferably in near-real time, and to generate dynamic three-dimensional information of the electrical activity occurring within the cerebral cortex of the brain. In the preferred embodiment, it can produce images that can be immediately inspected and analyzed by an operator in near-real time, resulting in a powerful new cortical imaging modality, which we denote as Dynamic Electrocortical Imaging (DECI). The present invention involves the use of a computer, an electroencephalographic (EEG) amplifier, EEG electrodes, and custom software. It can measure healthy and diseased cortical events and states in both conscious and unconscious subjects. This is useful, as it allows for the diagnosis, monitoring and treatment of cortical disorders, while also furthering the understanding of the human brain and lending use to additional non-medical applications such as in entertainment, education, lie-detection and industry. The invention in one embodiment is implemented using software in conjunction with readily available EEG hardware. Furthermore, this same method can be applied to pre-existing data and when doing so, EEG hardware is not required. Having a practical near-real time 3D imaging system brings a far more accessible technology to doctors, researchers, individuals, and private clinics to better diagnose, monitor, treat and understand many of the conditions and abnormalities of the brain.02-18-2010
20090156956Method of Determining Whether a Test Subject is a Specific Individual - This invention provides an EEG-based method of determining whether a test subject is a specific individual.06-18-2009
20090156955Methods and systems for comparing media content - Avatars, methods, apparatuses, computer program products, devices and systems are described that carry out presenting to at least one member of a population a plurality of avatars associated with at least one instance of media content; measuring at least one physiologic activity of the at least one member of the population, the at least one physiologic activity proximate to at least one presented avatar among the plurality of avatars associated with at least one instance of media content; associating the at least one physiologic activity with at least one mental state; and identifying at least one instance of media content based on the at least one mental state.06-18-2009
20100106043BRAIN FUNCTION PARAMETER MEASUREMENT SYSTEM AND METHOD - A method of fitting a proposed model for electro encephalography spectra to data derived from EEG recordings, the method comprising the steps of: (a) inputting at least one spectral trace of electroencephalographic measurements; (b) inputting a series of parameters associated with the proposed model; (c) applying a non-linear fitting algorithm to the at least one spectral trace and the at least one series of parameters, wherein the non-linear fitting model preferably can include a series of constraints associated with predetermined ones of the series of parameters so as to constrain the parameters in a predetermined range.04-29-2010
20100106042CORRECTION DEVICE TO BE INCORPORATED INTO BRAIN WAVE INTERFACE SYSTEM, ITS METHOD, AND COMPUTER PROGRAM - An option which is considered to be desired by a user is determined by using an electroencephalogram interface (IF), and a determination error for the option is detected based on an electroencephalogram. If a determination error is detected, the option is corrected based on the electroencephalogram information which was used for the option determination.04-29-2010
20100106041SYSTEMS AND METHODS FOR MULTICHANNEL WIRELESS IMPLANTABLE NEURAL RECORDING - A system for transmitting bioelectrical signals. The system includes an implantable bioelectrical sensor for receiving at least one bioelectrical signal; an analog-to-time converter for converting the received bioelectrical signal from an analog domain to a time domain signal; and a radio frequency (RF) modulator for transmitting the time domain signal. The the analog-to-time converter and the RF modulator are implantable in a living being.04-29-2010
20090124923System for seizure monitoring and detection - Systems and methods for the detection of pathological conditions in a brain analyze signal properties of the brain electrical activity recordings. The pathological conditions to be detected include the occurrence of a seizure event. The systems and methods calculate a seizure susceptibility index (SSI) for real time brain function monitoring and for a pre-screening process of seizure detection.05-14-2009
20090124921 Method for Monitoring Attentiveness and Productivity in a Subject - This invention provides an EEG-based method of determining whether a test subject is sufficiently alert to perform a predefined task. The non-invasive method permits continuous monitoring of the individual's EEG signal, producing a set of real time frequency bands that indicate their state of wakefulness. When the frequency bands begin to skew towards the lower end, indicating the onset of drowsiness and eventual sleep, the system optionally sounds an acute alarm tone to alert the individual back to attention. The method also provides remotely monitoring the alertness of an individual and can be used, for example, to monitor productivity. In addition, the technology monitors self-recognized errors through the utilization of the ERN waveform. The remote or in-person monitoring can be continuous for any period of time.05-14-2009
20090124920BIOFEEDBACK DEVICES, SYSTEMS AND METHOD - Biofeedback devices, systems, and methods for training enhanced performance are provided. A subject's EEG activity can be measured and analyzed, and a feedback signal can provide ongoing, continuous information regarding the subject's success in maintaining the brain's activity within a predetermined, desired state of enhanced performance. There are specific EEG patterns that maintain states of enhanced performance. The differential reduction and enlargement of the amplitudes of the various frequencies at specific sites that produce states of enhanced performance are measured. For example, enhanced performance can be produced when theta activity (4-8 Hz) and low-alpha activity (8-10 Hz) are maintained below a low-activity threshold while maintaining gamma activity (38-42 Hz) above a performance threshold amplitude (e.g., 0.5 microvolts). Additionally, positive feedback can also be withheld unless the subject maintains high-alpha activity (11-13 Hz) above a staging threshold value. The threshold settings used can be varied to target greater degrees of proficiency.05-14-2009
20120184869ELECTROENCEPHALOGRAM SIGNAL PROCESSING METHOD - An electroencephalogram signal processing method includes a recording step, a retrieving step, a removing step and a synthesizing step. The recording step retrieves EEG signal components of a testee via a plurality of electrodes, wherein the EEG signal components serve as an input signal. The retrieving step filters the input signal to obtain a predetermined frequency band signal, and subtracts the predetermined frequency band signal from the input signal to obtain a difference signal. The removing step performs an independent component analysis operation between the difference signal and a separating matrix to obtain an analysis signal, generates a separating pseudo inverse and an independent analysis signal, and performs a matrix operation between the separating pseudo inverse and the independent analysis signal to obtain a corrected signal. The synthesizing step adds the corrected signal and the predetermined frequency band signal together to obtain an output signal.07-19-2012
20120184868APPARATUS AND METHOD OF ENHANCING MEMORY ABILITY AND PARASYMPATHETIC ACTIVITY - An apparatus and a method of enhancing at least one of memory ability and parasympathetic activity of a subject are provided. The apparatus includes a training element for increasing a mu rhythm of the subject, and the method includes a step of increasing the mu rhythm of the subject.07-19-2012
20100069775EEG-Related Methods - This invention provides an EEG-based methods of determining whether a test subject is a specific individual, has a sufficiently positive attitude or is sufficiently alert to perform a pre-defined task.03-18-2010
20090043221APPARATUS AND METHOD FOR HIGH-SPEED DETERMINATION OF BIOELECTRIC ELECTRODE IMPEDANCES - Apparatuses and methods are provided for determining electrode impedances of a bioelectric signal-monitoring/recording system that includes an amplifier, and electrodes connected between a subject and the amplifier. An example apparatus includes: a voltage source outputting a voltage signal; a switching arrangement including an input electrically connected with the voltage source for receiving the voltage signal, an output electrically connected with the amplifier and the electrodes, and switches between the input and the output; and a controller in communication with the switches for opening and closing the switches to establish signal paths between the voltage source and the output, the controller calculating the electrode impedances relative to voltage outputs of the amplifier for each signal path.02-12-2009
20090043220METHODS AND DEVICES FOR ANALYSIS OF CLUSTERED DATA, IN PARTICULAR ACTION POTENTIALS (I.E. NEURON FIRING SIGNALS IN THE BRAIN) - Methods for clustering of multi-dimensional data allow unsupervised grouping of multi-dimensional data points into clusters having like characteristics. The methods may be usefully applied to extracellular action potentials (neuronal spikes) measured from the brain, whereby spike data may be grouped in accordance with dimensions such as spike period, spike shape, etc., to assist in identification and location of individual neurons and/or regions of the brain.02-12-2009
20090318825INVESTIGATING NEUROLOGICAL FUNCTION - This invention relates to a method and apparatus for identifying degenerative disorders and particularly to the early and accurate diagnosis of Alzheimer's Disease.12-24-2009
20090306534SYSTEMS AND METHODS FOR PREDICTING EFFECTIVENESS IN THE TREATMENT OF PSYCHIATRIC DISORDERS, INCLUDING DEPRESSION - The present invention pertains to the evaluation and/or treatment of psychopathological diseases. In one aspect, information regarding brain activity, coupled with behavior tests (e.g., determining performance in a computer-based task), may be used to predict the response of a subject to psychological treatment, e.g., with a psychoactive drug. For example, the subject may be one suffering from depression, or other disturbances of the rostral anterior cingulate cortex. Another aspect of the present invention is directed to methods for analyzing neurobiological predictors through integration of information gathered from one or more levels of analyses: (1) behavior, (2) brain function, and/or (3) genes. In one aspect, the methods of the present invention can comprise any one of these components (i.e., behavior, brain function, and genes), or a combination of two or more of these components, and/or other components. Through these methods, development of novel algorithms for improving the ability to identify biological surrogate markers of treatment response are disclosed, according to certain embodiments of the invention. Still other aspects of the present invention are directed to systems and methods for implementing such evaluation techniques, analyzing such evaluation techniques, promotion of such evaluation techniques, and the like.12-10-2009
20090306533Stroke Inducing and Monitoring System and Method for Using the Same - The present invention is a system and method for realtime monitoring of neural responses to stroke. The system of the present invention provides a component for inducing a localized stroke and one or more sensors for monitoring molecular and cellular physiological events before, during and after the stroke. Methods for inducing a stroke, monitoring neural responses, and identifying neuroprotective strategies and/or agents with a model are also provided.12-10-2009
20090306532Method for locating tracts of electrical brain activity - A method and apparatus for locating tracts of electrical brain activity. A source localization procedure may be performed including solving the inverse problem subject to one or more constraints resulting from a tractographic procedure, and a tractographic procedure may be performed that includes obtaining a probabilistic assessment of tract connectivity that takes account of the results of a source localization procedure.12-10-2009
20090306531METHODS AND SYSTEMS FOR CONTROLLING BODY PARTS AND DEVICES USING IPSILATERAL MOTOR CORTEX AND MOTOR RELATED CORTEX - A system for controlling a body part includes a number of sensing devices that sense signals from a hemisphere of a brain. A signal translating unit translates the signals into a command signal for controlling the body part, which is on a same side of the body as the hemisphere of the brain. A prosthetic device receives the command signal from the signal translating unit and manipulates the body part in response to the command signal.12-10-2009
20130072808STRUCTURED PROBES FOR NEURAL APPLICATIONS - A probe for recording and/or stimulating brain activity includes a connecting portion and at least one shank extending from the connecting portion. The at least one shank includes a first side, a second side opposed to the first side, and a fin protruding substantially perpendicularly from the second side and running on at least a part of a length of the at least one shank. The first side includes at least one recording and/or stimulating site.03-21-2013
20130072810Spatiotemporal Pattern Recognition for Neurological Event Detection and Prediction in an Implantable Device - A system and method for detecting and predicting neurological events with an implantable device uses a relatively low-power central processing unit in connection with signal processing circuitry to identify features (including half waves) and calculate window-based characteristics (including line lengths and areas under the curve of the waveform) in one or more electrographic signals received from a patient's brain. The features and window-based characteristics are employed within the framework of a programmable finite state machine to identify patterns and sequences in and across the electrographic signals, facilitating early and reliable detection and prediction of complex spatiotemporal neurological events in real time, and enabling responsive action by the implantable device.03-21-2013
20130072809Method And System For Analyzing An EEG Recording - A method and system for analyzing EEG data is disclosed herein. A processed EEG recording is analyzed to produce a parameter for the EEG. The EEG is analyzed to organize a plurality of detections by spike focus, to determine a relative frequency based on a count of detections by spike focus, to average a plurality of detections by spike focus, and the like.03-21-2013
20110015538SYSTEM AND METHOD FOR ANALYZING ELECTROENCEPHALOGRAPHY DATA - A system and method for analyzing EEG data. The system comprises data from at least one or all of the 19 (or more) standard scalp locations, a computing device 01-20-2011
20110015537METHOD, APPARATUS AND COMPUTER PROGRAM FOR MONITORING SPECIFIC CEREBRAL ACTIVITY - A method, apparatus and computer program product are disclosed for monitoring specific cerebral activity of a subject. Occurrences of a predetermined event are detected in each of at least two brain wave signals acquired from a subject, wherein the predetermined event is indicative of a specific cerebral activity. Based on the detecting, an event information signal is produced for each of the at least two brain wave signals, thereby to obtain at least two event information signals, each event information signal being indicative of occurrences of the predetermined event in respective brain wave signal. Based on the at least two event information signals, an overall event information signal is generated, which is indicative of an occurrence of the predetermined event when at least one of the at least two event information signals is indicative of an occurrence of the predetermined event within a given time window, thereby to obtain a signal representing a general view of the specific cerebral activity of the subject within a measurement area covered by the at least two brain wave signals.01-20-2011
20110015536EEG-based method for determining a subject's compatibility with a work environment - This invention provides an EEG-based method of determining whether a test subject possesses an attitude compatible with the work environment at a predetermined organization.01-20-2011
20130060158METHODS BASED ON FLUCTUATIONS IN CORTICAL SYNCHRONIZATION - A method of identifying a site of injury in a pediatric patient with brain injury is provided which comprises obtaining an electroencephalogram signal on the patient. The identification of phase synchrony within the signal is indicative of the site of brain injury. Electroencephalogram signals may also be used to determine prognosis of a pediatric patient in a coma in which an increase in the temporal variability of phase synchronized EEG signals over time is indicative of an improvement in the patient.03-07-2013
20090270754Control Apparatus, Control Method, Computer Program for the Control Method, and Recording Medium Having Recorded Therein the Computer Program for the Control Method - A control apparatus includes: a brain-activity-signal processing unit that processes plural brain activity signals and detects plural estimation values for estimating brain activity; and a control unit that controls a control target on the basis of the estimation values of the brain activity. The control unit switches a control target region of the control target according to at least one of the plural brain activity signals and controls the switched control target region according to the plural brain activity signals.10-29-2009
20090270753Device and Method For Deciding Necessity Of Brainwave Identification - In a system having an interface which utilizes electroencephalogram, it is determined whether the user was looking at a menu or not based on the frequency of the user electroencephalogram, and the electroencephalogram is excluded from the subject of distinction in the case where the user is not looking at the menu.10-29-2009
20120226185READINESS POTENTIAL-BASED BRAIN-COMPUTER INTERFACE DEVICE AND METHOD - The present invention provides a brain-computer interface device. The brain-computer interface device may include: a preprocessor for preprocessing a readiness potential signal measured by a brain wave detection device; a noise eliminator for eliminating noise from the preprocessed readiness potential signal; a signal processor for extracting features related to a user's intention by calculating at least one of the intensity of the readiness potential signal from which noise is eliminated, the phase of the readiness potential signal, the place where the readiness potential signal is generated, and the time when the readiness potential signal is generated; and a data classifier for classifying the extracted features to determine the user's intention.09-06-2012
20130165812Direct Neural Interface System and Method of Calibrating It - A direct neural interface system comprising: signal acquisition means (06-27-2013
20090076407Brain Function Scan System - A portable EEG (electroencephalograph) instrument, especially for use in emergencies and brain assessments in physicians' offices, detects and amplifies brain waves and converts then into digital data for analysis by comparison with data from normal groups. In one embodiment, the EEG electrodes are in a headband which broadcasts the data, by radio or cellular phone, to a local receiver for re-transmission and/or analysis. In another embodiment, the subject is stimulated in two modes, i.e., aural and sensory, at two different frequencies to provide the subject's EPs (Evoked Potentials), assessing transmission through the brainstem and thalamus.03-19-2009
20090234243ROBOTIC APPARATUS FOR TARGETING AND PRODUCING DEEP, FOCUSED TRANSCRANIAL MAGNETIC STIMULATION - Techniques for applying electromagnetic energy to deep, targeted areas without overwhelming other areas are provided. One or more coils are moved relative to a target area and magnetic fields are applied to the target from multiple coil locations. As a result, the aggregate electromagetic energy applied to the target over time is greater than surrounding areas. Additionally, a model for testing and treatment planning is provided.09-17-2009
20090234242Multi-Channel EEG Electrode System - A device comprises an indicating unit configured to indicate information and a connecting unit configured to connect the indicating unit to an electrode operable to sense an EEG signal, such that the information is indicated at a position at which the electrode is placed.09-17-2009
20100036275EEG NET WITH TRANSMISSION CAPABILITIES - An improved apparatus and method of using an EEG net to obtain electroencephalographic measurements from a patient in an emergent or urgent care setting. The net is comprised of a headpiece with a plurality of straps and recording ports formed therein. A recording head of an electrode is associated with each recording port and is pre-incorporated into the net. Transmitting wires are associated with each electrode head and have common terminating points. The terminus of each wire is hard wired into a connecting device that can be directly mated to a receiving console or remotely transmit wirelessly the electrode signals.02-11-2010
20090024049CROSS-MODALITY SYNTHESIS OF CENTRAL NERVOUS SYSTEM, AUTONOMIC NERVOUS SYSTEM, AND EFFECTOR DATA - An cross-modality response synthesizer analyzes and enhances central nervous system, autonomic nervous system, and effector data to a evaluate subject response to stimuli. A data collection mechanism obtains response data from a subject exposed to stimuli, such as marketing and entertainment stimuli. The cross-modality response synthesizer aligns and combines response data from multiple modalities to provide more accurate determinations of the effectiveness of stimuli. For example, facial emotion encoding measures are aligned and combined with electroencephalography (EEG) to enhance the valence of an EEG emotional engagement measure.01-22-2009
20090177108Method for Monitoring the Depth of Anesthesia - A method for monitoring the depth of anesthesia is provided for detecting the conscious state of one being anesthetized in the recovery phase or induction phase of anesthesia course in order to facilitate an anesthesiologist to predict exactly the dosage of an anesthetic required. At first, an original electroencephalogram (EEG) is taken from one being tested. Then, the original electroencephalogram is analyzed by approximate entropy to obtain its approximate entropy value. Next, the approximate entropy value is multiplied by 1000/17, and the corrected value is assumed as the predicted value of depth of anesthesia. The predicted value of depth of anesthesia represents degree of the conscious state or the depth of anesthesia for the one being tested. The higher the predicted depth of anesthesia value, the more conscious the one being tested is, i.e., in a shallower depth of anesthesia. On the other hand, the lower the predicted depth of anesthesia value, the less conscious the one being tested is, i.e., in a deeper depth of anesthesia.07-09-2009
20080294062LOW-POWER ANALOG ARCHITECTURE FOR BRAIN-MACHINE INTERFACES - An ultra-low-power circuit for wireless neural recording and stimulation is provided. The circuit includes a neural amplifier with adaptive power biasing for use in multi-electrode arrays and a decoding and/or learning architecture. An impedance-modulation telemetry system provides low-power data telemetry. Also, the circuit includes a wireless link for efficient power transfer, and at least one circuit for wireless stimulation of neurons.11-27-2008
20090036791Neuronal Avalanche Assay - Method and system for determining a cognitive enhancement and/or anti-epileptic effect comprising: detecting synchronized neuronal activity in neuronal tissue (02-05-2009
20120203131Extracranial Monitoring of Brain Activity - Methods and systems for monitoring a subject's brain activity are provided. A method includes receiving EEG signals from the subject using a plurality of EEG electrodes positioned extracranially; and recording EEG signals using a recording circuit coupled to said EEG electrodes and contained in an enclosure implanted beneath the subject's scalp and above the subject's caldarium.08-09-2012
20090124922Method for Real Tima Attitude Assessment - This invention provides an EEG-based method of determining whether a test subject possesses a sufficiently positive attitude to perform a predefined task with a second subject who is known to the test subject.05-14-2009
20110282233LOW-POWER REAL-TIME SEIZURE DETECTION SYSTEM - A method for detecting an approaching seizure is disclosed. The method includes receiving an analog neurosignal from an electrode, comparing the analog neurosignal with a predetermined amplitude threshold to generate a plurality of digital transitions corresponding to the analog neurosignal transitioning from a first level below the predetermined amplitude threshold to a second level above the predetermined amplitude threshold, generating a plurality of comparator signals, each comparator signal of the plurality of comparator signals corresponding to a comparison of a length of time between a pair of digital transitions of the plurality of digital transitions and a predetermined temporal threshold, and generating a seizure detection signal if at least two of the comparator signals of the plurality of comparator signals are enabled. A seizure detection system for detecting an approaching seizure is also disclosed.11-17-2011
20090137921DEVICE AND METHOD FOR DETECTING AN EPILEPTIC EVENT - The invention discloses an epileptic event alert system, capable of detecting and analyzing whether motions sensed by at least one motion sensor of the system, are related to an epileptic seizure event. The system may be utilized for detection of additional motion-related pathologies. A detection method is similarly disclosed, as is computer-readable media adapted to perform the detection method of the invention.05-28-2009
20100191139Method and Device for Probabilistic Objective Assessment of Brain Function - A method and apparatus for providing objective assessment of the brain state of a subject using a field portable device. The method includes placing an electrode set coupled to a handheld base unit on the subject's head, acquiring electrical brain signals from the subject through the electrode set, processing the acquired electrical brain signals using a feature extraction algorithm, classifying the extracted features into brain states, computing brain abnormality indices reflecting the probability of correct classification of brain state, and graphically displaying the classification result and the abnormality indices on the handheld base unit.07-29-2010
20090264785Method and Apparatus For Assessing Brain Function Using Diffusion Geometric Analysis - A method of extracting features and classifying a neurological state of a subject is provided. The method includes recording brain electrical activity, organizing the recorded data set into digital documents, computing a diffusion geometry on the data set comprising at least a plurality of diffusion coordinates, and classifying the data set into a neurological state based on the metrics provided by the diffusion coordinates.10-22-2009
20110301487METHOD AND APPARATUS FOR DETERMINING SLEEP STATES - An apparatus is provided for detecting Macro Sleep Architecture states of a subject such as WAKE, NREM and REM sleep from a subject's EEG. The apparatus includes an EEG digital signal assembly of modules arranged to convert analogue EEG signals into digital EEG signals. A bispectrum assembly is responsive to the EEG digital signal assembly and converts the digital EEG signals into signals representing corresponding bispectrum values. A bispectrum time series assembly, in electrical communication with an output side of the bispectrum assembly, generates at least one bispectrum time series for a predetermined frequency. A macro-sleep architecture (MSA) assembly is responsive to the bispectrum time series assembly and is arranged to produce classification signals indicating classification of segments of the EEG signals into macro-sleep states of the subject.12-08-2011
20110301486MEASUREMENT OF AUDITORY EVOKED RESPONSES - The invention relates to a method of measuring an electroencephalogram signal in response to an auditory stimulus applied to a subject or patient (12-08-2011
20100249638NEURODIAGNOSTIC MONITORING AND DISPLAY SYSTEM - A process for analysing an electroencephalogram (EEG) signal representative of activity of a brain of a subject, including: (i) generating coefficient data for a signal representation of a portion of the EEG signal; (ii) generating, based on the coefficient data, cortical state data representing the brain's receptivity to subcortical input and input from other areas of cortex; (iii) generating cortical input data representing a level of subcortical input to the brain at a time corresponding to the portion of the EEG signal; (iv) generating, based on the cortical state data and the cortical input data, display data representing the functional state of the brain of the subject; and (v) displaying the display data on display means.09-30-2010
20100249637SYSTEMS, DEVICES, AND METHODS FOR TREATING RESTLESS LEG SYNDROME AND PERIODIC LIMB MOVEMENT DISORDER - Systems, devices, and methods for treating restless leg syndrome and periodic limb movement disorder that may include sleeve apparatus and vibration apparatus to stimulate the limb(s) of a subject.09-30-2010
20100249636PERSONALIZED STIMULUS PLACEMENT IN VIDEO GAMES - A system analyzes neuro-response measurements from subjects exposed to video games to identify neurologically salient locations for inclusion of stimulus material and personalized stimulus material such as video streams, advertisements, messages, product offers, purchase offers, etc. Examples of neuro-response measurements include Electroencephalography (EEG), optical imaging, and functional Magnetic Resonance Imaging (fMRI), eye tracking, and facial emotion encoding measurements.09-30-2010
20100249635HEARING SCREENING SYSTEM FOR A SUBJECT OR A PATIENT, AND A METHOD FOR HEARING SCREENING - An auditory stimulus device in a first aspect for applying an auditory stimulus to at least one ear of a subject; at least three electrodes for electrically connecting to at least three different positions on a head of the subject for measuring respective potential changes in response to the auditory stimulus; two galvanically isolated power supplies; two differential amplifiers arranged for receiving galvanically isolated supply voltages from the power supplies. In a second aspect the system comprises one (or more) electroencephalographic (EEG) channels with one differential amplifier, wherein the differential amplifier is arranged for amplifying a potential difference between the pair of electrodes for obtaining an amplified EEG signal on an output of the differential amplifier, wherein the differential amplifier is configured for first amplifying the potential difference with a total differential gain and subsequently taking a difference between respective output potentials of the amplified potential difference.09-30-2010
20090062679CATEGORIZING PERCEPTUAL STIMULI BY DETECTING SUBCONCIOUS RESPONSES - A perceptual stimulus categorization technique is presented which identifies the stimuli category of a perceptual stimulus that has been presented to a person whose brain activity is being monitored. This generally accomplished by first training a detection module to recognize the part of the brain activity generated in response to the presentation of a stimulus belonging to each of one or more stimuli categories using brain activity information. Once the detection module is trained, a subsequent instance of a stimulus belonging to a trained stimuli category being presented to the person is detected, and this detection is used to identify the trained stimuli category to which the presented stimulus belongs.03-05-2009
20100069777BRAIN FUNCTION DECODING PROCESS AND SYSTEM - A method of interpreting cognitive response to a stimulus is disclosed. The method includes collecting baseline neural activity data from a subject absent a stimulus. Neural activity data is collected while the subject is being stimulated through exposure to a stimulus. A unique three-dimensional cognitive engram is then plotted representative of cerebral regions of stimulated neural activity caused by the stimulus. A novel graphical representation is plotted in three dimensions to indicate the brain region response unique to that stimulus.03-18-2010
20110295143BRAIN FUNCTION MAPPING - A method for identifying a functional area of a brain. The functional area is associated with a neurological function. The method includes applying a plurality of electrodes to a surface of the brain. A slow cortical potential is determined based on one or more electrical signals produced by the plurality of electrodes. A covariance pattern is computed based on the slow cortical potential, and the configuration of co-varying electrodes is used to identify one or more areas of the brain associated with the neurological function. These co-varying patterns may be used in conjunction with other electrical and/or physiological stimulation paradigms.12-01-2011
20110295142Detector for identifying physiological artifacts from physiological signals and method - The present invention relates to a physiological monitor and system, particularly to an electroencephalogram (EEG) monitor and system, and a method of detecting the presence and absence of artifacts and possibly removing artifacts from an EEG, other physiological signal or sensor signal without corrupting or compromising the signal. The accurate, real-time detection of the presence or absence of artifacts and removal of artifacts in EEG or other signals allows for increased reliability in the efficacy of those signals. The strategy of rejecting artifact-corrupted EEG can result in unacceptable data loss, and asking subjects to minimize movements in order to minimize artifacts is not always feasible. The present invention allows for increased accuracy in detection and removal of artifacts from physiological signals, substantially in real time, and without loss or corruption of signal or data in order to increase the accuracy of such signals for diagnosis and treatment purposes.12-01-2011
20100016752SYSTEM AND METHOD FOR NEUROLOGICAL ACTIVITY SIGNATURE DETERMINATION, DISCRIMINATION, AND DETECTION - A system and method are provided for automatically correlating neurological activity to a predetermined physiological response. The system includes at least one sensor operable to sense signals indicative of the neurological activity, and a processing engine coupled to the sensor. The processing engine is operable in a first system mode to execute a simultaneous sparse approximation jointly upon a group of signals sensed by the sensor to generate signature information corresponding to the predetermined physiological response. The system further includes a detector coupled to the sensors, which is operable in a second system mode to monitor the sensed signals. The detector generates upon selective detection according to the signature information a control signal for actuating a control action according to the predetermined physiological response.01-21-2010
20100010363DETERMINATION OF NEUROPSYCHIATRIC THERAPY MECHANISMS OF ACTION - A computer implemented method, apparatus, and computer program product of determining mechanisms of action for therapies. A first set of brain scans for each subject in a plurality of subjects generated at a first time period and a second set of brain scans for each subject generated at a second time period are received. Each subject is diagnosed with a given condition and received a given therapy. A set of changes in the set of brain scans is identified for the each subject based on a comparison of a first set of regions of interest in the first set of scans for each subject with a second set of regions of interest in the second set of scans for each subject. A set of typical changes attributable to the given therapy is identified. A mechanism of action for the given therapy is generated based on the set of typical changes.01-14-2010
20090099473Apparatus and Method for Acquiring a Signal - An electrode cap for obtaining EPM signals from a head of a subject, the cap comprising: (i) an insulating layer (04-16-2009
20110144522Single Trial Detection in Encephalography - An EEG cap (06-16-2011
20090156954Method, Apparatus and Computer Program Product For Assessment of Attentional Impairments - A method, apparatus, and computer useable medium that provides, among other things, a standardized test protocol for screening and evaluation of attentional impairment using EEG data. Further, the method, apparatus, and computer program product enhances existing psychological, behavioral, and physiological EEG data acquisition systems by introducing a sequential stochastic model procedure, and an intelligent data interpretation component capable of assessing EEG inconsistencies associated attentional impairments. Potential users of this product will be any person or organization that diagnoses or treats persons with attentional or cognitive impairments. The method can be used for initial screening and diagnosis of disorders associated with impaired attention, such as ADHD, as well as for treatment and evaluation of the effects of treatments, such as medication or additional therapies.06-18-2009
20100113959TRANSCRANIAL MAGNETIC STIMULATION (TMS) METHODS AND APPARATUS - In one aspect, a portable transcranial magnetic stimulation (TMS) device for delivering a TMS procedure is provided. The portable TMS device comprises at least one coil that, when energized, generates electromagnetic energy, a helmet adapted to fit a user's head and configured to hold the at least one coil in a predetermined position with respect to the user's head, and a port having at least one power connection coupled to the at least one coil, the at least one power connection adapted to connect the at least one coil to a power source capable of energizing the at least one coil, the port further comprising at least one data connection adapted to exchange data with at least one external component, the port being located on the helmet. In another aspect a method of positioning a coil with respect to a person's head to target a desired region of the person's brain with transcranial magnetic stimulation (TMS) is provided. The method comprises obtaining a dielectric property map of a portion of the brain, the dielectric map indicating a spatial distribution of at least one dielectric property over the portion of the brain, determining a location for the coil based, at least in part, on the dielectric property map, the location being such that when the coil is positioned at the location, magnetic energy generated by the coil is focused on the desired region, and positioning the coil at the determined location.05-06-2010
20090149770Alertness/Drowsiness and Cognitive Capacity Index - The invention includes a method and system for providing an Index representing the alertness state of an individual based at least in part on EEG signals obtained from the individual. In at least one embodiment, the EEG signals are divided into frequency bands and a total amplitude of the power is determined. Based on the proportion of the high frequency band compared to the proportion of the low frequency band, an Index is determined that is indicative of an individual's ability to perform a cognitive task.06-11-2009
20090149769PLAID MOTION RIVALRY FOR DIAGNOSIS OF PSYCHIATRIC DISORDERS - A method and apparatus for diagnosing a psychiatric disorder or, a predisposition thereto, in a test subject is provided, wherein perceptual rivalry is measured in the test subject during exposure to a moving plaid stimulus. The method may include the step of determining an interhemispheric switch rate of the test subject, and comparing the switch rate with a corresponding reference switch rate to diagnose presence or absence of the psychiatric disorder. Particular psychiatric disorder s include mood disorders and schizophrenia. Also provided is use of the diagnostic method in genetic linkage studies for the identification of the molecular defect(s) underlying a psychiatric disorder, and for the identification of compounds which may alleviate the disorder.06-11-2009
20120108996Wireless Controlled Neuromodulation System - An apparatus is disclosed for controlled neuromodulation. The apparatus includes a plurality of neural sensors, wherein each of the neural sensors is electrically connected to a separate signal conditioner. Each of the signal conditioners produces a neural sensor signal, which is analyzed by a separate threshold detector to produces a neural event signal when the neural sensor signal exceeds a threshold level associated with the threshold detector. Each of the threshold detectors is connected to a wireless transceiver and the wireless transceivers transmit the neural event signals to a processor. The processor analyzes the neural event signals and determines the presence or absence of a clinical brain state. The apparatus can be used to detect and control epileptic seizures.05-03-2012
20120108995NEURO-RESPONSE POST-PURCHASE ASSESSMENT - Efficient and effective mechanisms for collecting neuro-response data are provided to allow assessment of post-purchase products, services, offerings, and experiences. In some examples, a neuro-response data collection mechanism such as a portable electroencephalography (EEG) headset is used to collect neuro-response data from a consumer exposed to a product in a post-purchase state. Post-purchase assessments may be made at particular times after a purchase transaction. A post-purchase assessment may be compared to a pre-purchase assessment. The assessments can be used to enhance product packaging, modify service components, improve sustained experiences, change consumer behavior, etc.05-03-2012
20090299209METHOD AND DEVICE FOR THE DETECTION OF MICROSLEEP EVENTS - Disclosed herein is a method of detecting a microsleep event in a subject. The method includes determining a number of eye openness factors by measuring a number of distances between an upper eyelid and a lower eyelid of at least one eye over a time period. Graphical representations of the eye openness factors are then generated. Changes in the eye openness factors over the time period are correlated with a reference eye closure pattern indicative of the microsleep event. Also disclosed is a microsleep event detection device.12-03-2009
20080269632Systems and Methods for Analyzing and Assessing Attention Deficit Hyperactivity Disorder - Embodiments of the invention can provide systems and methods for analyzing and assessing attention deficit hyperactivity disorder (ADHD) by integrating the use of electroencephalography (EEG), and ADHD diagnostic and assessment tools, such as an ADHD rating scale. Embodiments of the invention can provide some or all of the following improvements over conventional systems and methods, including: (1) Increased sensitivity, specificity, and overall accuracy; (2) Improved detection of ADHD; and (3) Distinguishing subjects with ADHD from subjects with a different disorder but having ADHD-like symptoms, such as attention and behavior symptoms similar to ADHD.10-30-2008
20090076406METHOD AND APPARATUS FOR OBJECTIVE ELECTROPHYSIOLOGICAL ASSESSMENT OF VISUAL FUNCTION - For electrophysiological assessment of visual function using a head mounted stereo display (e.g. virtual reality goggles) for displaying a stimulus which is used to generate a retinal or cortical response. In particular, a method for objective electrophysiological assessment of visual function of at least one eye of a subject includes presenting a visual stimulus to at least one eye of the subject, recording at least one of a retinal response and, a cortical response generated as a result of the presenting; analyzing said response and, as a result of said analyzing, forming a map of the visual function of the at least one eye of the subject03-19-2009
20100030096METHOD OF ACQUIRING A PHYSIOLOGICAL RESPONSE - A method for acquiring a physiological response from a test subject, particularly an auditory brainstem response, by presenting a plurality of stimuli, such as a Maximum Length Sequence, detecting electrophysiological signals in response to the stimuli, generating a recover signal based on the stimuli and determining the physiological response from the electrophysiological signals and the recovery signal.02-04-2010
20100081959DIAGNOSTIC APPARATUS - Diagnostic apparatus featuring biological feedback for diagnosing a patient (04-01-2010
20100125219MINIMALLY INVASIVE SYSTEM FOR SELECTING PATIENT-SPECIFIC THERAPY PARAMETERS - The present invention provides systems and methods for ambulatory, long term monitoring of a physiological signal from a patient. At least a portion of the systems of the present invention may be implanted within the patient in a minimally invasive manner. In preferred embodiments, brain activity signals are sampled from the patient and are transmitted to a handheld patient communication device for further processing.05-20-2010
20100100001FIXATION-LOCKED MEASUREMENT OF BRAIN RESPONSES TO STIMULI - Fixation-locked measurement of brain activity generates time-coded cues indicative of whether an operator exhibited a significant cognitive response to task-relevant stimuli. The free-viewing environment is one in which the presentation of stimuli is natural to the task encompassing both pre- and post-fixation stimuli and the operator is allowed to move his or her eyes naturally to perform the task.04-22-2010
20120071781ELECTRODE SYSTEM WITH IN-BAND IMPEDANCE DETECTION - An apparatus comprises a headset and a control unit in communication with each other. The headset comprises a plurality of electrodes operable to measure ERP readings. The headset is configured to be positioned on a test subject. The control unit is configured to store and administer an ERP test protocol. The control unit is also configured to administer an impedance test and process the impedance of the electrodes. The impedance testing may be performed in an in-band fashion, along the same channels used to perform the ERP testing, at the same frequency of the ERP readings, and substantially simultaneously with the ERP readings.03-22-2012
20090275853METHOD AND APPARATUS FOR MONITORING PHYSIOLOGICAL STATE OF A SUBJECT - A method and apparatus for monitoring physiological state of a subject is disclosed. Physiological signal data obtained from a subject is decomposed into a plurality of signal subentities, such as subbands of the overall frequency band of the signal data. A first measure indicative of the entropy of the respective signal subentity is determined for each of the subentities, thereby to obtain a corresponding plurality of first measures. An aggregate entropy measure is then calculated from the plurality of first measures and the aggregate entropy measure is employed to produce at least one state index indicative of a physiological state of the subject. The aggregate entropy measure typically represents a sum of the plurality of first measures.11-05-2009
20090281447METHOD OF AFFECTING BALANCED BRAIN FUNCTION WITH RELATIONAL AMBIENT SOUND - A method for affecting balanced brain functioning with relational ambient sound is disclosed. During the process of balancing the brain's activity, an ambient sound is played for the subject to hear. The subject's brain develops a relationship between the process of bringing the brain to a balanced state and the ambient sound. As a result of this relationship, balanced brain functioning may then be affected by exposing the subject to that same ambient sound.11-12-2009
20100185114Electrode Placement for Remote Monitoring - A method of placing ECG electrodes in an environment where persons of limited training are available includes making a trial placement of the electrodes. Then, testing the electrodes and evaluating signals from the electrodes as a result of the testing. Verbal or visual feedback can be provided to the person placing the electrodes so that placed electrodes could be adjusted as needed.07-22-2010
20090281446SYSTEM AND DEVICE FOR SEIZURE DETECTION - A device comprises a head mounting arrangement sized and shaped to be worn on a user's head and a plurality of electrodes disposed on the arrangement so that, when the arrangement is worn on the user's head, the electrodes contact target portions of a scalp to detect electrical activity of a brain of the user in combination with an image capture device disposed on the arrangement so that, when the arrangement is worn on the user's head, a field of view of the image capture device includes a portion of an anatomy of the user and a processing unit generating EEG data from the electrical activity, wherein, when the EEG data is indicative of an epileptic event, the processing unit activates the image capture device to capture video data of the user and may store the EEG and/or the video data with transmission of warning signals to one or more remote displaying and/or computing arrangements. 11-12-2009
20090287108SYSTEM FOR STUDY AND TREATMENT OF BEHAVIOR DYSREGULATION - A method for changing appearance of EEG or a relationship of brain wave patterns while achieving behavioral changes, the method including individualized assessing of dysregulated patterns of brain function using topographic quantitative electroencephalogram (LORETA [low resolution brain electromagnetic tomography] qEEG) or regular EEG recollection, modifying or priming neuroplasticity with transcranial direct current stimulation (tDCS) or with magnetic or electromagnetic fields to modify cortical excitability of neurons in dysregulated areas, and self-regulating LORETA patterns with neurofeedback to change an appearance of EEG or a relationship of brain wave patterns while achieving behavioral changes.11-19-2009
20090287107Analysis of eeg signals to detect hypoglycaemia - Features indicative of hypoglycaemia in EEG signals are detected by: —dividing EEG signals into a sequence of time segments, —for each time segment determining whether a pattern of EEG signals is present which is indicative of hypoglycaemia and, where a pattern of EEG signals indicative of hypoglycaemia is determined to be present in a time segment, recording this as an event, —integrating the number of events recorded during a selected number of preceding time segments which together constitute a selected time period, optionally in a time weighted manner, and—determining that the EEG signals are indicative that hypoglycaemia is present based on said integration when the said integrated number of events exceeds a preset threshold number and/or when there exists a threshold level of matching between a curve of said integration over time and a previously established ideal model of said curve indicative of hypoglycaemia.11-19-2009
20120271189METHOD AND APPARATUS FOR ASSESSING NEURAL ACTIVATION - Various embodiments concern sensing a LFP signal from one or more electrodes, measuring the amplitude of the signals over a period of time, and calculating a plurality of variance values from the amplitude, wherein each of the variance values correspond to the variance of the amplitude for a different interval of time of the period of time with respect to the other variance values. Such embodiments may further include assessing the relative level of neural activation of an area of the brain based on the variance values, wherein the area of the brain is assessed to have a relatively higher level of neural activation when the variance is relatively higher and the area of the brain is assessed to have a relatively lower level of neural activation when the variance is relatively lower.10-25-2012
20090048530MONITORING OF EPILEPTIFORM ACTIVITY - The invention relates to monitoring of epileptiform activity. In order to accomplish a mechanism with improved specificity to epileptiform activity and with the capability to provide a clinician enough information for selecting a precision-targeted drug at an early phase of a seizure, first and second indicators are derived from the brain wave signal data obtained from a subject, the indicators being respectively indicative of the level of underlying neuronal excitation and neuronal inhibition. Based on the first and second indicators, an indication of the level of at least one of the neuronal excitation and neuronal inhibition is given to an end-user.02-19-2009
20130218043MENTAL DISORDER ANALYSIS APPARATUS, MENTAL DISORDER ANALYSIS METHOD, AND PROGRAM - A mental disorder analysis apparatus includes a storage portion in which sleep electroencephalogram information, which is information on electroencephalograms during sleep of a test subject, is stored, an analyzing portion that performs analysis regarding presence or absence of a mental disorder using the sleep electroencephalogram information stored in the storage portion, and an output portion that outputs a result of the analysis performed by the analyzing portion.08-22-2013
20100217147 ELECTROENCEPHALOGRAPHY MONITORING DEVICE HAVING A SELF-ADAPTIVE ANALOG-TO-DIGITAL CONVERTER - An EEG monitoring device, contains at least one electrode, a non-linear analog signal processor, a variable resolution analog-to-digital converter, a storage, and a power source. The non-linear analog signal processor receives a signal from the at least one electrode and determines whether the signal is within a significant category. The variable resolution analog-to-digital converter converts signals received from the non-linear analog signal processor into high-resolution digital signals if the signals are within the significant category, and converts signals received from the non-linear analog signal processor at a low resolution if the signals are not within the significant category. The storage stores high-resolution digital signals received from the variable resolution analog-to-digital converter and the power source is connected to, and provides power to, the non-linear analog signal processor, the variable resolution analog-to-digital converter, and the storage.08-26-2010
20100298735Methods For Classifying And Treating Physiologic Brain Imbalances Using Quantitative EEG - Neurophysiologic information such as quantitative electroencephalography (QEEG) is used in a method for classifying, diagnosing, and treating physiologic brain imbalances. Neurophysiologic information is also used to guide sample selection in clinical tests for psychopharmacologic drug candidates. Finally, neurophysiologic information is used for remotely assessing and treating patients with physiologic brain imbalances.11-25-2010
20090069706BRAIN PROBE ADAPTED TO BE INTRODUCED THROUGH A CANULA - A bio-probe having a base and a tip and also including a set of at least four conductors extending longitudinally along the bio-probe, the conductors being coated with dielectric material. Also, at least four of the conductors define a spot where the dielectric material has been removed, thereby defining an electrical contact site. In addition, the bio-probe is less than 2.5 mm thick in its greatest transverse dimension along a longitudinal portion extending from the tip to a point 6 cm proximal of the tip.03-12-2009
20080249431BURST SUPPRESSION MONITOR FOR INDUCED COMA - Methods and systems for monitoring subjects, analyzing EEG data, and maintaining subjects at desired sedation states.10-09-2008
20080275359Mobile in vivo brain scan and analysis system - Described is a mobile in vivo brain scan and analysis system. The system includes a data collection subsystem and a data analysis subsystem. The data collection subsystem is formed to collect brain data that is reflective of firing neurons in a mobile subject and transmit the brain data to the data analysis subsystem. The data analysis subsystem is configured to generate and display a three-dimensional image that depicts a location the firing neurons. The data analysis subsystem is also configured to compare the brain data against a library of brain data to detect an anomaly in the brain data, and notify a user of any detected anomaly in the brain data.11-06-2008
20080275358TRAINING METHOD AND APPARATUS EMPLOYING BRAINWAVE MONITORING - Training methods and apparatus wherein a training environment is activated only when a trainee is in a focused attention state. A brainwave monitor is employed for determining level of attention. The training environment is activated when the level of attention of the trainee is at or above a predetermined attention threshold. Activation of the training environment provides feedback to the trainee that he or she is in a focused attention state, and at the same time provides the incentive to remain in the focused attention state. A focused attention state is important if not required for training/learning success. The method and apparatus may be employed for training individual trainees, as well as for training team member trainees.11-06-2008
20110144518System and Methods for Management of Disease Over Time - A system for delivering health information is provided. The system comprises at least one apparatus configured to receive information related to a condition of a patient. The analysis system further comprises a reception system configured to receive data related to the patient's condition and a processor configured to assess a condition of a patient and to identify a data set including information related to the patient's condition. The system also comprises a communication system configured to communicate the data set to a user.06-16-2011
20110144520METHOD AND DEVICE FOR POINT-OF-CARE NEURO-ASSESSMENT AND TREATMENT GUIDANCE - A method and apparatus for providing an objective assessment of the neurological state of a patient using a field-portable neuro-assessment device is described. The method includes placing an electrode set on the patient's head, acquiring spontaneous brain electrical signals and evoked potential signals from the patient through the electrode set, processing the signals using a handheld base unit, and displaying a result indicating the probability of the patient's neurological signal being normal or abnormal. The neuro-assessment device allows for a rapid, on-site neurological evaluation by an emergency medical technician, triage nurse, or any other medical personnel to identify patients with neurological disorders who may require immediate medical attention.06-16-2011
20110144519System and Methods for Neurologic Monitoring and Improving Classification and Treatment of Neurologic States - Methods and systems for assessing brain activity and collecting information related to a patient's condition and brain electrical activity are provided.06-16-2011
20090054800Method and Device for Representing A Dynamic Functional Image of the Brain, By Locating and Discriminating Intracerebral Neuroelectric Generators and Uses Thereof - The invention relates to a method of representing a dynamic functional image of the brain. It consists in acquiring (A) for a specific duration a plurality of electrophysiological signals {es02-26-2009
20080287821Computational user-health testing - Methods, apparatuses, computer program products, devices and systems are described that carry out accepting at least one user-health test function output at least partly based on an interaction between at least one user and at least one device-operable application; accepting brain activity measurement data proximate to the interaction; associating the at least one user-health test function output with the brain activity measurement data; and presenting the at least one user-health test function output and the brain activity measurement data at least partly based on the associating the at least one user-health test function output with the brain activity measurement data.11-20-2008
20080287822Method and system for representing brain activities - A system for representing brain activities in the form of visual patterns has been described. The system comprises a signal frequency modulator (frequenzer) and a resonating chamber. The signal frequenzer receives a signal corresponding to a brain activity and generates an audio signal corresponding to the received signal. The resonating chamber receives the audio signal and generates a visual pattern corresponding to the received audio signal. The visual pattern may be recorded by using a camera and displayed on a display device.11-20-2008
20080294063Method and apparatus for the estimation of anesthetic depth using wavelet analysis of the electroencephalogram - A method and apparatus to monitor the neurologic state of a patient undergoing general anesthesia is provided. Previous automated systems to monitor the neurologic state of a patient undergoing general anesthesia involve a significant time delay between the patients true hypnotic state and the computed indices. The present invention reduces this time delay by using a different analysis technique applied to spontaneous EEG. A wavelet decomposition and statistical analysis of the observed EEG is conducted and compared to reference data to provide a numerical indicator. In addition, this indicator is more consistent with the patient's loss of consciousness indicated by the loss of count event than previous systems.11-27-2008
20080269631Seizure prediction - Seizure prediction systems and methods include measuring impedance within a brain of a patient to determine whether the brain is in a state indicative of a possibility of an onset of a seizure. In some embodiments, the measured impedance is compared to a predetermined threshold in order to determine whether the brain is in a state indicative of a possibility of a seizure. In other embodiments, a trend of the impedance measurements is correlated to a template. In other embodiments, a frequency component of a waveform of the impedance measurement amplitudes over time is correlated to frequency components of a template waveform. Upon detecting a state in which a seizure is likely to occur, a seizure indicator may be generated, which, in some embodiments, may be used to activate therapy delivery to the patient or, in other embodiments, activate an alarm.10-30-2008
20080269630Seizure prediction - Seizure prediction systems and methods include measuring impedance and a potential within a brain of a patient to determine whether the brain is in a state indicative of a possibility of seizure. In some embodiments, at least one of the measured impedance or the measured potential may be used as a primary indication of the brain state indicative of a possibility of seizure. In one embodiment, if one of the measured impedance or the measured potential indicates a seizure, the other measurement (impedance or potential) may be used to validate whether the brain is in the state indicative of the possibility of seizure.10-30-2008
20090264789THERAPY PROGRAM SELECTION - A set of therapy parameter values is selected based on a patient state, where the patient state comprises a speech state or a mixed patient state including the speech state and at least one of a movement state or a sleep state. In this way, therapy delivery is tailored to the patient state, which may include one or more patient symptoms specific to the patient state. In some examples, a medical device determines whether the patient is in the speech state or a mixed patient state including the speech state based on a signal generated by a voice activity sensor. The voice activity sensor detects the use of the patient's voice, and may include a microphone, a vibration detector or an accelerometer.10-22-2009
20090264787Communication and Device Control System Based on Multi-Frequency, Multi-Phase Encoded visual Evoked Brain Waves - In a driving control system actuated by visual evoked brain waves which are induced by a multi-frequency and multi-phase encoder, and a corresponding method configured for analyzing brain wave signals in order to control at least one peripheral equipment, the driving control system includes an optical flash generating device, a brain wave signal measurement device, a signal processing and analyzing device and a control device. The optical flash generating device is configured for generating at least one flash light source by a multi-frequency and multi-phase encoder. The brain wave signal measurement device is configured for measuring a brain wave signal inducing by a user gazing the flash light source. The signal processing and analyzing device is configured for calculating the frequency and the phase of the brain wave by a mathematical method, and analyzing whether the frequency and the phase of the brain wave same to the those of the optical flash generating device. The control device is configured for sending out the frequency and the phase analyzed by the signal processing and analyzing device and same to those of the optical flash generating device so as to control at least one peripheral equipment.10-22-2009
20090264786System and Method For Signal Denoising Using Independent Component Analysis and Fractal Dimension Estimation - A system and method of signal denoising using Independent Component Analysis (ICA) and fractal dimension analysis of the signal components in the ICA domain is described. The signal components with fractal dimensions higher than a pre-determined threshold are automatically attenuated or canceled in order to alleviate the noise in the signal. The denoised signal is reconstructed using inverse ICA transform of the signal components.10-22-2009
20080208073FIELD-DEPLOYABLE CONCUSSION DETECTOR - A method and apparatus for providing an on-site diagnosis of a subject to determine the presence and/or severity of a concussion is provided. The method includes placing an electrode set coupled to a handheld base unit on the subject's head, acquiring brain electrical signals from the subject through the electrode set, processing the acquired brain electrical signals using a signal processing algorithm stored in a memory of the base unit, determining the presence and/or severity of a concussion from the processed signals, indicating the presence and/or severity of a concussion on the handheld base unit, and determining a course of treatment for the subject based on the indication.08-28-2008
20080269633Sonification of Level of Consciousness of a Patient - The level of consciousness of a patient (i.e. the hypnotic state and/or the level of anaesthesia) is represented aurally. A measure of the patient's level of consciousness, such as the BIS index value, is obtained, and an audio signal is synthesized from that measure, and then output through a speaker. Both the volume and pitch of the audio signal may vary according to the BIS value being represented, so that a clinician can obtain an indication of the level of consciousness of the patient simply by listening to the sonification of the BIS value. The audio signal may comprise first and second audio components, with the first component representing the previous measure and the second component representing the current measure. The amplitude or pitch of the audio signal may be modulated to represent analgesia or paralysis of the patient.10-30-2008
20100145215BRAIN PATTERN ANALYZER USING NEURO-RESPONSE DATA - A system obtains neuro-response data such as central nervous system, autonomic nervous system, and effector system measurements from subjects exposed to stimulus material. Stimulus material is categorized and/or tagged. Survey based responses and resulting linguistic, perceptual, expressive, and/or motor responses are obtained, integrated with neuro-response data, and stored in a brain pattern analyzer repository. Neurological signatures for concepts such as yes, no, buy, purchase, acquire, like, dislike, correct, incorrect can be determined on a group, subgroup, or individual basis and stored in the brain pattern analyzer repository. The brain pattern analyzer repository may be used to predict behavior based on neurological signatures and/or similarly categorized and tagged stimulus materials that elicit corresponding neuro-response patterns for particular subject groups.06-10-2010
20090088658METHOD AND SYSTEM FOR SUBJECT-ADAPTIVE REAL-TIME SLEEP STAGE CLASSIFICATION - A method of subject-adaptive, real-time sleep stage classification to classify electroencephalogram sleep recordings into sleep stages to determine whether a subject exhibits a sleep disorder includes performing subject adaptation to improve classification accuracy for a new subject with limited training data, the performing subject adaptation comprises using linear-chain conditional random fields and potential functions, training the linear-chain conditional random fields using the training data, continuously receiving the electroencephalogram waves, continuously extracting features from the electroencephalogram waves, the extracting features comprising transforming each of the electroencephalogram waves to capture information embedded in the electroencephalogram waves, and continuously classifying the sleep stages according to extracted features and learned parameters from the linear-chain conditional random fields.04-02-2009
20090124919LOW POWER HARDWARE ALGORITHMS AND ARCHITECTURES FOR SPIKE SORTING AND DETECTION - A neuronal recording system featuring a large number of electrodes and a portable wireless front-end integrated circuit for signal processing for low-power spike detection and alignment. The system is configured as a Neuroprocessor and introduces hardware architectures for automatic spike detection and alignment algorithms. The Neuroprocessor can be placed next to the recording electrodes and provide for all stages of spike processing, stimulating neuronal tissues and wireless communications to a host computer. Some of the algorithms are based on principal component analysis(PCA). Others employ a novel Integral Transform. The algorithms execute autonomously, but require off-line training and setting of computational parameters. Pre-recorded neuronal signals evaluate the accuracy of the proposed algorithms and architectures: The recorded data are processed by a standard PCA spike sorting software algorithm, as well as by the several hardware algorithms, and the outcomes are compared.05-14-2009
20120197152METHOD AND SYSTEM FOR EEG ARTIFACT CORRECTION IN COMBINED EEG AND FUNCTIONAL MRI RECORDING - Artifacts are removed from EEG signals by segmenting EEG data that are continuously recorded during an MR scan with respect to a time period based on the MR scan, thereby obtaining n temporally consecutive segments of EEG data. For each segment j of the n segments, it is determined whether movement is detected when the segment j is recorded. In the case of no movement, the segment j is selected for a template k. In case movement is detected, EEG data of segments of the n temporally consecutive segments which have been selected for the template k are averaged, thereby obtaining the template k, the template k is subtracted from the EEG data of the segments, k is incremented, and the segment j is selected for the template k. In case no movement is detected and j=n, the segment j is selected for the template k and EEG data of segments of the n temporally consecutive segments which have been selected for the template k are averaged, thereby obtaining the template k, and the template k is subtracted from the EEG data of the segments.08-02-2012
20090137923Electroencephalography based systems and methods for selecting therapies and predicting outcomes - A method and system for utilizing neurophysiologic information obtained by techniques such as quantitative electroencephalography (QEEG), electrode recordings, MRI in appropriately matching patients with therapeutic entities is disclosed. The present invention enables utilization of neurophysiologic information, notwithstanding its weak correlation with extant diagnostic schemes for mental disorders, for safer and expeditious treatment for mental disorders, discovering new applications for therapeutic entities, improved testing of candidate therapeutic entities, inferring the presence or absence of a desirable response to a treatment, and deducing the mode of action of one or more therapeutic entities. In particular, methods for effectively comparing neurophysiologic information relative to a reference set are disclosed along with database-based tools for deducing therapeutic entity actions on particular patients such that these tools are readily accessible to remote users.05-28-2009
20100268108Computational systems and methods for health services planning and matching - Systems and methods are described relating to detecting an indication of at least one attribute of an individual; accepting sensor data about the individual; and presenting a set of health care options at least partially based on the detecting an indication of at least one attribute of the individual and the accepting sensor data about the individual.10-21-2010
20100004556BRAIN WAVE IDENTIFICATION METHOD ADJUSTING DEVICE AND METHOD - In a system having an interface that utilizes an electroencephalogram, there is realized a calibration which prevents overlooking of calibrational stimulations concerning the electroencephalogram and which is highly accurate.01-07-2010
20090062680ARTIFACT DETECTION AND CORRECTION SYSTEM FOR ELECTROENCEPHALOGRAPH NEUROFEEDBACK TRAINING METHODOLOGY - The method for simultaneously and concurrently identifying and quantifying a wide variety of types of facial electromyographic (EMG) and eye movement electrooculargraphic (EOG) activity, which naturally contaminate electroencephalographic (EEG) waveforms in order to significantly improve the accuracy of the calculation in real-time of the amplitude and/or coherence of any brainwave activity for any chosen frequency bandwidth for any number of electrode placements. This multi-level, widely or universally applicable, pre-defined pattern recognition artifact detection and correction system provides a method for enhancing EEG biofeedback training by detecting and eliminating any brief, contaminated epoch of EEG activity from being included in the calculation and analysis of the EEG signal. The method and apparatus disclosed herein make it possible to provide without any interruption visual, auditory and/or tactile feedback of a “true” EEG signal that through operant conditioning learning principles enables individuals to more quickly and easily learn to control their brainwave activity using neurofeedback.03-05-2009
20090062677Method of Recording and Saving of Human Soul for Human Immortality and Installation for it - The inventor shows that a human soul is only the information in human brain. He offers a method for re-writing the human brain on electronic chips. This method allows for the modeling of a human soul in order to achieve man immortality. This method does not damage the brain but works to extend and enhance it.03-05-2009
20090143695BRAINWAVE-FACILITATED PRESENTER FEEDBACK MECHANISM - A system includes a presentation subsystem, at least one communications port to receive communications from at least one headset, a processor to process the communications and to produce an aggregated audience response to a presentation on the presentation system, and a status communications module to present the aggregated audience response to a presenter. A computer-controlled method of monitoring interest levels receives at least two signals containing brain wave data for at least one user during a presentation, analyzes the brain wave data to determine a mental state for each user, aggregates the mental states into an aggregate mental state for an audience, and provides the aggregate mental state to a presenter.06-04-2009
20090326404Single trial detection in encephalography - An EEG cap (12-31-2009
20090326405TECHNIQUES FOR DETERMINING HEARING THRESHOLD - A computerized method for determining a test subject's (TS) hearing threshold (HT). An acoustic stimulus (AS, 12-31-2009
20090247893METHOD AND APPARATUS FOR MEASURING RESPONSIVENESS OF A SUBJECT - The invention relates to a method and apparatus for measuring the responsiveness of a subject. Physiological signal data is obtained from a subject through at least one electrode attached to the skin of the subject and a first measure is derived from the physiological signal data, the first measure being indicative of signal energy in the physiological signal data on a frequency band where EMG activity appears. Recorded sequence of the first measure is subjected as input data to a morphological pattern extraction operation. The output data of the operation is indicative of presence of predetermined response waveforms in the input data and a measure of responsiveness is determined based on the output data.10-01-2009
20090024050Computational user-health testing - Methods, apparatuses, computer program products, devices and systems are described that carry out accepting user brain activity measurement data; selecting at least one user-health test function at least partly based on the user brain activity measurement data; and applying the at least one user-health test function to at least one interaction between at least one user and at least one device-implemented application.01-22-2009
20080306397Apparatuses and Methods For Electrophysiological Signal Delivery and Recording During Mri - Methods, systems and arrangements are provided for obtaining electroencephalograph (“EEG”) EEG signals from a patient e.g., during a concurrent EEG/MRI examination of the patient. The methods, systems and arrangements include a cap made of conductive inks with sensor positions for attaching a plurality of sensors to the patient's head. The sensors can include electrodes as well as motion sensors for improving EEG signal quality and MRI image quality in the presence of motion noise and other artifacts within the MRI environment. The electrodes may be composed of conductive inks, and can be used in high magnetic fields due to a weak interaction with the RF fields generated by the MRI scanner. The exemplary methods, systems and arrangements can achieve lower SAR and lower temperature increase, as compared to conventional electrodes.12-11-2008
20090198145COMPOSITIONS, METHODS, AND SYSTEMS FOR RAPID INDUCTION AND MAINTENANCE OF CONTINUOUS REM SLEEP - Compositions, kits, methods, and systems to induce, maintain, monitor, and interpret a continuous, un-fragmented REM sleep state in humans, generate dreams, recover sleep, create brain neuronal plasticity and activate the brain for cognition enhancement and mood stabilization are described. If potentially combined with other medications, a platform is provided to develop new research and therapies in many fields treating the human brain. The procedure reliably and quickly generates a Continuous REM Sleep cycle of pre-determined time or indefinite duration depending on therapeutic goals, allowing the patient to experience a qualitatively superior dream sleep in a shortened period of time compared to a natural sleep cycle. Profuse positive (pleasant) dreams are produced as well. REM sleep, dreams and sleep recovery can be reliably generated, and various sleep, psychological and neurological illnesses and disorders can be treated or prevented either solely by this method or in combination with additional agents.08-06-2009
20090198144Systems and Methods for Anxiety Treatment Using Neuro-EEG Synchronization Therapy - Described are methods, devices, and systems for a novel, inexpensive, easy to use therapy for treatment of anxiety. Described are methods and devices to treat anxiety that involves no medication. Methods and devices described herein use alternating magnetic fields to gently “tune” the brain and affect symptoms of anxiety.08-06-2009
20110144521STIMULATION ELECTRODE SELECTION - Bioelectrical signals may be sensed within a brain of a patient with a plurality of sense electrode combinations. A stimulation electrode combination for delivering stimulation to the patient to manage a patient condition can be selected based on a frequency domain characteristic of the sensed bioelectrical signals. In some examples, a stimulation electrode combination is selected based on a determination of which of the sense electrodes are located closest to a target tissue site, as indicated by the one or more sense electrodes that sensed a bioelectrical brain signal with a relatively highest value of the frequency domain characteristic. In some examples, determining which of the sense electrodes are located closest to the target tissue site may include executing an algorithm using relative values of the frequency domain characteristic.06-16-2011
20090062676PHASE AND STATE DEPENDENT EEG AND BRAIN IMAGING - The present invention provides methods and devices for performing electroencephalographic (EEG) phase dependent brain imaging using evoked and event related potentials (EP, ERP) or other forms of brain imaging including functional magnetic resonance imaging (fMRI) and magnetic encephalography (MEG). The methods and devices can be used for a variety of purposes, including for the study of normal and pathological cognitive function, and for the diagnosis and prognosis of neurological and sleep disorders.03-05-2009
20090062678Method and Apparatus for Prediction and Warning of Hypoglycaemic Attack - The present invention includes a method and device for warning of hypoglycaemic attacks, which is a big problem for especially diabetics, who are in insulin treatment. It is estimated that about 1 million people have a decreased quality of life as a result of hypoglycaemic attacks. The invention collects EEG signals from people, who must be supervised and analyses these in order to detect characteristic changes in the EEG signals, which occurs in advance of a hypoglycaemic attack. In a preferred embodiment the EEG signals are collected with subcutaneously placed electrodes and the signals are lead via wires drawn under the person's skin to a similar subcutaneously placed signal processing unit. The signal processing analyses the EEG signals and when the pre-seizure characteristics signal changes are detected, a warning signal is given to the person from an alarm giver build into the signal processing unit, e.g. in form of a vibrator. When a person detects a warning signal, the person can prevent the hypoglycaemic attack by e.g. consuming a sugary food.03-05-2009
20090062681CONTENT BASED SELECTION AND META TAGGING OF ADVERTISEMENT BREAKS - A system evaluates stimulus materials such as videos, imagery, web pages, text, etc., in order to determine resonance and priming levels for various products and services at different temporal and spatial locations including advertisement breaks in the stimulus materials. The stimulus materials are tagged with resonance and priming level information to allow intelligent selection of suitable advertisement content for insertion at various locations in the stimulus materials. Response data such as survey data and/or neuro-response data including Event Related Potential (ERP), Electroencephalography (EEG), Galvanic Skin Response (GSR), Electrocardiograms (EKG), Electrooculography (EOG), eye tracking, and facial emotion encoding data may be used to determine resonance and priming levels.03-05-2009
20110230781APPARATUS AND METHOD FOR DEMENTIA DIAGNOSIS THROUGH EEG (ELECTROENCEPHALOGRAM) ANALYSIS - The present invention provides an apparatus and a method for early diagnosis of dementia which measure and evaluate dimensional complexity or the generation of synchronized brain wave signals on a specific frequency or in a specific frequency band, based on the brain wave signals measured from a multi-channel brain wave measurement system. The apparatus comprises: a measurement unit with electrodes having plural channels for measuring brain wave signals; an amplification unit which amplifies brain wave signals measured by the measurement unit; a dementia diagnosis unit which measures dimensional complexity or the generation degree of synchronized brain wave signals on a specific frequency or in a specific frequency band based on the amplified brain wave signals; and a dementia determination unit which diagnoses dementia based on the dimensional complexity or the degree of synchronization measured in the dementia diagnosis unit.09-22-2011
20090082691FREQUENCY SELECTIVE MONITORING OF PHYSIOLOGICAL SIGNALS - In general, the disclosure is directed to a frequency selective monitor and methods for monitoring physiological signals in one or more selected frequency bands. A frequency selective monitor may utilize a heterodyning, chopper-stabilized amplifier architecture to convert a selected frequency band to a baseband for analysis. The frequency selective monitor may be useful in a variety of therapeutic and/or diagnostic applications. As examples, a frequency selective signal monitor may be provided within a medical device or within a sensor coupled to a medical device. The physiological signal may be analyzed in one or more selected frequency bands to trigger delivery of patient therapy and/or recording of diagnostic information.03-26-2009
20110224570METHOD AND APPARATUS FOR AUTOMATIC EVOKED POTENTIALS ASSESSMENT - Systems and methods for assessing a patient's neurologic state based on auditory evoked responses are provided.09-15-2011
20090204015Systems and Methods for Depression Treatment Using Neuro-EEG Synchronization Therapy - Described are methods, devices, and systems for a novel, inexpensive, easy to use therapy for treatment of depression. Described are methods and devices to treat depression that involves no medication. Methods and devices described herein use alternating magnetic fields to gently “tune” the brain and affect symptoms of depression.08-13-2009
20090082690Systems and Methods for Neuro-EEG Synchronization Therapy - Described are methods, devices, and systems for a novel, inexpensive, easy to use therapy for a number of disorders. Described are methods and devices to treat disorders that involves no medication. Methods and devices described herein use alternating magnetic fields to gently “tune” the brain and affect mood, focus, and cognition of subjects.03-26-2009
20080262371Method for Adaptive Complex Wavelet Based Filtering of Eeg Signals - A method for adaptive filtering of EEG signals in the wavelet domain using a nearly shift-invariant complex wavelet transform. EEG signal data is segmented into a set of K “trials” or “light averages” of M-frames of data each. These trials are overlapped by a number of frames P, where P10-23-2008
20090221930QUESTIONS AND CONTROL PARADIGMS FOR DETECTING DECEPTION BY MEASURING BRAIN ACTIVITY - Methods for determining whether the brain activity of a human subject in response to a stimulus of interest or question of interest is characteristic of a state of interest, such as a deceptive state or a truthful state, are disclosed. Some methods include the use of control questions, including truthful control questions and deceptive control questions, to provide bases for comparison for responses to stimuli of interest or questions of interest. Some methods include the use of differences between two states, such as a deceptive state and a truthful state. In some methods, brain maps are generated and compared. Also disclosed are systems for detecting deception by measuring brain activity.09-03-2009
20090221929Method and Arrangement for the Analysis of a Time-Variable Bioelectromagnetic Signal - In a method for analysis of a time-variable bioelectromagnetic signal that has been recorded over a certain time interval, the signal is split by a bandpass filter into at least two signal components that differ with regard to their frequency ranges. At least one reference point of a first kind is determined in at least one of the signal components that differ with regard to their frequency ranges in accordance with predetermined selection criteria. The values of at least two signal components that differ with regard to their frequency ranges at the determined reference points of the first kind are correlated with one another according to predetermined evaluation criteria.09-03-2009
20100121214SEIZURE DISORDER EVALUATION BASED ON INTRACRANIAL PRESSURE AND PATIENT MOTION - Intracranial pressure of a patient may be monitored in order to evaluate a seizure disorder. In some examples, trends in the intracranial pressure over time may be monitored, e.g., to detect changes to the patient's condition. In addition, in some examples, a seizure metric may be generated for a detected seizure based on sensed intracranial pressures. The seizure metric may indicate, for example, an average, median, or highest relative intracranial pressure value observed during a seizure, a percent change from a baseline value during the seizure, or the time for the intracranial pressure to return to a baseline state after the occurrence of a seizure. In addition to or instead of intracranial pressure, patient motion or posture may be monitored in order to assess the patient's seizure disorder. For example, a seizure type or severity may be determined based on patient motion sensed during a seizure.05-13-2010
20090105603Apparatus for measuring brain local activity - For measuring a brain local activity, a predetermined frequency bandwidth wider than a frequency bandwidth of alpha waves of scalp potentials is divided into a predetermined number of frequency banks each having a fixed frequency width, data of each divided frequency bank is divided into segments of a predetermined duration on a time axis, a Z-score of the subject is determined from a first mean value of normalized power variances determined for the segments and a second mean value of normalized power variances predetermined in the same manner as the first mean value for a predetermined normal person group and a standard deviation of the normalized power variances in the group, and a mean value of the Z-scores determined over all of the frequency banks is mapped on a brain surface for each sensor, whereby a template of a specified brain disorder and likelihood of a subject to a specified brain disorder are calculated.04-23-2009
20090221928Motor training with brain plasticity - A rehabilitation device, comprising a movement element capable of controlling at least one motion parameter of a portion of a patient; a brain monitor which generates a signal indicative of brain activity; and circuitry including a memory having stored therein rehabilitation information and which inter-relates said signal and movement of said movement element as part of a rehabilitation process which utilizes said rehabilitation information.09-03-2009
20090247894Systems and Methods For Neurological Evaluation and Treatment Guidance - A system for acquiring and processing a subject's brain electrical activity is provided. The system includes at least one electrode, at least one analog amplifier channel, an analog-to-digital converter, a stimulus generator, and a digital signal processor configured to perform a harmonic signal analysis algorithm. The at least one analog amplifier channel, the analog-to-digital converter, and the digital signal processor are configured on a single integrated physical circuit. All the components of the system are configured to reside on a common portable unit to make the system easily applicable at the point-of-care. The system records and processes a subject's spontaneous neuroelectric signals as well as evoked potentials in real-time, and generates analyzed data representative of a subject's neurophysiological condition.10-01-2009
20090259136Method and system for analyzing and presenting an Electroencephalogram (EEG) - A system and method determines from EEG signals the lack of awareness and the depth of anesthesia of a patient to whom an anesthetic agent is being administered. In particular, a log-log representation of the EEG power spectrum is converted to two intersecting lines so that the intersection point and the relative slopes can be analyzed to determine a state of awareness of a patient. This system and method may also be used in an analysis of the brain function of a sleeping individual to distinguish between different levels of non-REM sleep, REM sleep, and awakeness.10-15-2009
20090253996Integrated Sensor Headset - A device is described that integrates sensors into a housing which can be placed on a human head for measurement of physiological data. The device includes at least one sensor and a reference electrode connected to the housing. A processor coupled to the sensor and the reference electrode receives signals that represent electrical activity in tissue of a user. The processor generates an output signal including data of a difference between an energy level in each of a first and second frequency band of the signals. The difference between energy levels is proportional to release level present time emotional state of the user. The device includes a wireless transmitter that transmits the output signal to a remote device. The device therefore processes the physiological data to create the output signal that correspond to a person's mental and emotional state (response).10-08-2009
20100274152DEVICE AND METHOD FOR PERFORMING ELECTROENCEPHALOGRAPHY10-28-2010
20090318824NEURALPROBE AND METHODS FOR MANUFACTURING SAME - A neural probe and method of fabricating same are provided. The probe comprises a plurality of frames connected to each other and to a substrate by respective bimorphs. A probe base is connected by another bimorph to the frames. A probe tip extends from the probe base. The probe can achieve a large vertical motion and out-of-plane curling. The probe can operate according to three modes. The first mode pertains to a large-signal motion for tuning in single-unit neuronal activity. The second pertains to a small-signal motion with lock-in amplifier that increases SNR. The third pertains to burst small-signal motion for clearing tissue responses. Fabrication of a neural probe begins with a processed CMOS chip. Post-CMOS processing incorporates self-aligned selective nickel plating and sacrifices two aluminum layers. The fabrication technique produces a neural probe in which the sensing elements are in close proximity to CMOS circuitry. The fabrication technique obviates the need for post-CMOS masks, alignment, or assembly.12-24-2009
20100152602WHOLE BODY ELECTROMAGNETIC DETECTION SYSTEM - An apparatus and method for characterizing electrical signals from a living organism comprising sensors configured to be positioned to receive the electrical signals emanating from a human signal source. A processor may be configured to interpret readings made by the sensors to output a characterization of the electrical signals.06-17-2010
20090082692System And Method For The Real-Time Evaluation Of Time-Locked Physiological Measures - In one embodiment, a method is provided for classifying cognitive activity in an individual. In the method, a candidate time interval is identified from a first type of physiological data within which cognitive processing is expected to occur for the individual. In addition, a second type of physiological data is obtained that comprises data representative of a cognitive state of the individual. Further, the data representative of a cognitive state of the individual is extracted from the second type of physiological data based on the identified candidate time interval.03-26-2009
20100191140METHOD FOR CONTROLLING DEVICE BY USING BRAIN WAVE AND BRAIN WAVE INTERFACE SYSTEM - The control method for a device includes steps of: presenting a visual stimulation concerning a manipulation menu for a device; measuring event-related potentials after the visual stimulation is presented, where event-related potentials based on a timing of presenting the visual stimulation as a starting point are measured from a potential difference between each of electrodes and at least one reference electrode respectively worn on a face and in an ear periphery of a user; from each of the measured event-related potentials, extracting electroencephalogram data which is at 5 Hz or less and contains a predetermined time section, and combining the extracted electroencephalogram data into electroencephalogram characteristic data; comparing the electroencephalogram characteristic data against reference data prepared in advance for determining a desire to select an item in the manipulation menu; and, based on a comparison result, executing a manipulation of the device corresponding to the item.07-29-2010
20100185115APPARATUS FOR EVOKING AND RECORDING BIO-POTENTIALS - Apparatus (07-22-2010
20120143075Apparatus and method for monitoring, analyzing, and utilizing brainwave and biologic data at transition points along the neurochromometric sequence whereby a stimulus presented to the central nervous system results in cognition and volitional action - Apparatus and method for monitoring, analyzing, and utilizing brainwave and biologic data at transition points along the neurochromometric sequence whereby a stimulus is presented to the central nervous system results in cognition and volitional action.06-07-2012
20120143074METHOD OF EVALUATING SUITABILITY FOR DRUG THERAPY FOR THE PREVENTION AND TREATMENT OF ANXIETY DISORDERS USING CHOLINERGIC TYPE II THETA RHYTHM - The present invention relates to a drug suitability assessment method for the prevention or treatment of anxiety disorders using the cholinergic type II theta rhythm, and, more specifically, to a method for detecting individuals suffering from anxiety disorders induced by an abnormality occurring in the cholinergic system using the type II theta rhythm profile which is based on findings that the cholinergic type II theta rhythm is lower in an animal anxiety model than in normal subjects and that cholinergic drug treatment induces the cholinergic type II theta rhythm to return to normal and reduces anxiety and thereby making it possible to determine if a subject can be appropriately administered with a cholinergic drug and to monitor progress after cholinergic drug treatment.06-07-2012
20090082689METHOD AND APPARATUS FOR REDUCING THE NUMBER OF CHANNELS IN AN EEG-BASED EPILEPTIC SEIZURE DETECTOR - An ambulatory patient-specific epileptic seizure detector based on scalp EEG signals is presented. A method for selecting a patient-specific subset of electrodes from a plurality of m EEG channels needed to detect an epileptic seizure in the patient is also presented. Seizure EEG data is collected from the plurality of m EEG channels. An effective subset n of the channels of the plurality of m EEG channels is selected using recursive feature processing and a detector is constructed in response to the subset n of channels. The performance of the detector in detecting seizures is then estimated.03-26-2009
20100241021DISTRACTION DETECTION APPARATUS, DISTRACTION DETECTION METHOD, AND COMPUTER PROGRAM - The distraction detection apparatus includes: an electroencephalogram detection section for detecting an electroencephalogram signal of a driver; an arousal level estimation section for retaining a first rule of mapping parameter values of an electroencephalogram signal to arousal levels, and estimating an arousal level based on the detected electroencephalogram signal and the first rule; an attention allocation estimation section for retaining a second rule of mapping parameter values of an electroencephalogram signal to attention allocations, and estimating an attention allocation based on the detected electroencephalogram signal and the second rule; a driver state estimation section for retaining a third rule of deriving an amount of attention from an arousal level and an attention allocation, estimating an amount of attention of the driver paid to driving based on the estimated arousal level and attention allocation and the third rule, and classifying a state of the driver into a normal state, a state of reduced attention, or a state of reduced arousal level; and an output section for performing an intervention for the driver based on a result of classification by the driver state classification section.09-23-2010
20100145218ADJUSTMENT DEVICE, METHOD, AND COMPUTER PROGRAM FOR A BRAINWAVE IDENTIFICATION SYSTEM - In a system having an interface which utilizes an electroencephalogram, device operations which are not intended by the user are reduced.06-10-2010
20100241020Real-time methods and systems for mapping a target region in the brain during surgery - A real-time method and system to accurately demarcate sub-territories of the subthalamic nucleus area in the brain during surgery, based on microelectrode recordings and a Hidden Markov Model. Root mean square and power spectral density of the microelectrode recordings are used to train and test Hidden Markov Model in identifying the dorsolateral oscillatory region and non-oscillatory sub-territories within the subthalamic nucleus. After the dorsolateral oscillatory region in the subthalamic nucleus is mapped, the microelectrodes are removed, and a macroelectrode is inserted in the mapped dorsolateral oscillatory region for producing deep brain simulation for treatment of Parkinson's disease.09-23-2010
20100145214 SYSTEM AND METHOD FOR PROCESSING BRAIN SIGNALS IN A BCI SYSTEM - A system and method for processing brain signals in a BCI system. The method of processing brain signals in a BCI system includes the steps of processing the brain signals for control state detection to determine if a subject intends to use the BCI system; and processing the brain signals for command recognition if the control state detection method determines that the subject intends to use the BCI system.06-10-2010
20110112426Brain Activity as a Marker of Disease - A method of monitoring brain activity is provided, wherein the method includes receiving a signal associated with neuronal activity of a mammalian brain. The method also includes processing the signal using a linear, non-linear, or combination algorithm to extract a signal feature. A neuromarker may be determined based on an association between the signal feature and a library of features, wherein the library includes a plurality of signal features correlated with a plurality of disease states.05-12-2011
20120130266COGNITIVE EFFICACY ESTIMATION SYSTEM AND METHOD - A system and method for estimating cognitive efficacy of an individual is provided. The individual is subjected to a plurality of tasks. Electroencephalogram (EEG) data from EEG sensors coupled to the individual are collected while the individual is performing the plurality of tasks. The EEG data are supplied to a trained classifier that generates an estimate of cognitive effort of the individual for each of the plurality of tasks performed by the individual.05-24-2012
20130218042SYSTEMS AND/OR METHODS FOR STIMULATING THE BRAIN TO PROMOTE LEARNING AND/OR TO PROVIDE THERAPEUTIC TREATMENTS THERETO - Certain example embodiments of this invention relate to systems and/or methods for stimulating the brain, e.g., to promote learning and/or memory, to provide therapeutic treatments thereto, etc. In certain example embodiments, neurons are monitored and their activities are analyzed to determine the electrical and electrochemical pathways that are activated during specific learning functions, events, etc. Given an established mapping, certain example embodiments deliver electrical and electrochemical signals to specifically targeted brain locations in order to facilitate learning and/or memory, to provide therapeutic treatments thereto, etc. For example, neurons or gateways thereto may be stimulated to facilitate learning, memory and/or recall, to counteract or mitigate the onset or arrival of mental or neurological diseases and disorders, etc.08-22-2013
20100210963Method for assessing anesthetization - An evaluation of consciousness during the application of anesthetic evaluates causal propagation of neural activity in response to a localized stimulus, for example, by transcranial magnetic stimulation. A longer duration of invoked activity and a greater spatial dispersion of the invoked activity or greater complexity are matched to greater wakefulness comporting with a theory of consciousness as cortical integration of information moderated by intraneural communication.08-19-2010
20100210964IMPLANTABLE SEIZURE MONITOR - An implantable seizure monitor can include at least one sensing electrode and an electronics module configured to detect, record and/or log neurological events. For example, the electronics module can be configured to detect brainwaves indicative of seizures, such as, for example, epileptic seizures, and to create a log indicating when such seizures occur. The implantable seizure monitor can include a cushioning member made of a soft material and configured to be implantable between the epidermis and cranium of a patient.08-19-2010
20100198098System for the prediction, rapid detection, warning, prevention, or control of changes in activity states in the brain of a subject08-05-2010
20090247895APPARATUS, METHOD, AND COMPUTER PROGRAM FOR ADJUSTMENT OF ELECTROENCEPHALOGRAMS DISTINCTION METHOD - In a system having an interface utilizing electroencephalograms, a user's burden of calibration for accurately measuring electroencephalograms is eliminated, and it becomes possible to maintain a high distinction accuracy of electroencephalograms.10-01-2009
20110034821Increasing the information transfer rate of brain-computer interfaces - Methods of increasing the rate of information transfer in brain-computer interface systems are disclosed. The present invention also discloses methods, devices and systems for the navigation of information representing neuronal or brain activity and the extraction of useful and/or actionable data from such information.02-10-2011
20110130675MULTI-CHANNEL BRAIN OR CORTICAL ACTIVITY MONITORING AND METHOD - The present invention relates to a quantitative electroencephalogram (QEEG) monitor and system capable of monitoring and displaying simultaneously neuropathological characteristic and activity of both sides of a subject's brain. The methods include various indices and examination of differences in these indices by which neurophysiological conditions or problems can be identified and treated. These methods, and the systems and devices using these methods preferably can be used for identifying these neurophysiological conditions or brain dysfunction with monitors and methods for seizure detection, for sedation monitoring, for anesthesia monitoring, and the like. These bilateral brain monitoring methods and systems, and the devices using these methods can be used by individuals or clinicians with little or no training in signal analysis or processing. These bilateral monitoring methods can also be used in a range of applications.06-02-2011
20090112117Electrophysiological assessment of the integrity of cerebral vasculature - The present invention discloses a method for monitoring the blood flow in the cerebral vasculature of a subject. The method includes measuring the electrophysiological activity of different regions in the brain in the excited or unexcited state. The measured electrophysiological activity of each region is then compared with the baseline of the electrophysiological activity of that region for the corresponding state. External stimuli or the performance of specific tasks by the subject can be used to excite different regions of the brain. Any deviation in the measured electrophysiological activity from the baseline indicates an altered blood flow in that region of the brain. Identification of this particular region of the brain which has altered activity can be carried out based on the external stimuli that resulted in the altered activity. Specific branches of the cerebral vasculature with an altered blood flow may also be determined based on the regions of the brain showing altered electrophysiological activity.04-30-2009
20110112427SYSTEMS AND METHODS FOR NEURO-EEG SYNCHRONIZATION THERAPY - Described are methods, devices, and systems for a novel, inexpensive, easy to use therapy for a number of disorders. Described are methods and devices to treat disorders that involves no medication. Methods and devices described herein use alternating magnetic fields to gently “tune” the brain and affect mood, focus, and cognition of subjects.05-12-2011
20130138009Method And System For Displaying EEG Data - A method and system for displaying EEG data is disclosed herein. A plurality of epochs are stitched together with an overlapping section in order to present a continuous EEG recording. Artifact reduction is performed on the epochs and then the epochs are combined together with overlapping sections of preferably two to four seconds.05-30-2013
20130138010User Interface For Artifact Removal In An EEG - A method and system for a user interface for artifact removal in an EEG is disclosed herein. The invention allows an operator to select a plurality of artifacts to be automatically removed from an EEG recording using a user interface. The operator pushes a button on the user interface to apply a plurality of filters to remove the plurality of artifacts from the EEG and generate a clean EEG for viewing.05-30-2013
20110172554Patient Entry Recording in an Epilepsy Monitoring System - Systems and methods for monitoring a patient are provided. The system includes: an implantable sensor adapted to collect neurological signals; an implantable assembly configured to sample the neurological signals collected by the sensor; and a rechargeable external assembly configured to wirelessly receive the sampled neurological signals from the implantable assembly, said external assembly being further configured to record a patient entry in response to receiving an input from the patient. The method includes: collecting neurological signals with a sensor implanted in the patient; sampling the neurological signals collected by the sensor with an implantable assembly implanted in the patient; and transmitting the sampled neurological signals from the implantable assembly to a rechargeable external assembly external to the patient; and recording a patient entry in response to receiving an input from the patient.07-14-2011
20110172553QEEG Statistical Low Resolution Tomographic Analysis - A system and method for analyzing electrophysical signals produced by a brain involves comparing a first selected one of the numerical values to control data including one of a self-norm and a population-norm associated with electrophysical activity in a brain region corresponding to a brain region of origin of the electrophysical activity on which the numerical value is based; calculating a standard score for the brain region of origin based on the comparing; and repeating the comparing and calculating operations for a second selected one of the numerical values, the regions of the brain including subcortical regions extending to a brain stem of the brain.07-14-2011
20110004114Cognitive information encoding conversion telecommunication system and conferencing method - This invention relates to a scanless system for- and method of teleportation of cognitive perceptions as events in series in conjunction with- or without radio-telephone frequency applications. In the invention, an event includes the focal content of bound percepts in a source-subject. The invention describes the process whereby the quantum nature of the information-bearing content of those percepts, whether founded on physical or mental (imaginary) stimuli can be transceived through the invention as concept modules whose origins lie within the data-free elements of sensory organ electromagnetic radiation frequency wave responses to the source-subject's individually-directed and subjectively-generated emotions. At the core, the assembly identifies a method for capturing the engagement between photon-carrying information and transmissions to the receiving-subject or -devices using spintronic-based evaluation for a plurality of inputs and a plurality of outputs with a radio-frequency telephone-enabled assembly, governed by quantum key distribution protocols and time-dependent delay processors.01-06-2011
20110245708APPARATUS AND METHOD FOR HUMAN ALGOMETRY - An apparatus and method for performing human algometry are disclosed. They include a stimulator configured to apply electrical stimulation of variable intensity to an area of a patient's body, a monitoring device configured to measure a. level of cortical activity in one or more regions of the patient's brain, and a microprocessor connected to the stimulator and the monitoring device that is configured to correlate the intensity of the electrical stimulation with the level of activity in the one or more regions of the patient's brain and to determine at least one of a measurement of pain intensity, a measurement of a sensory detection threshold (SDT), a measurement of a drug's analgesic impact, an indication of an onset of tolerance to a drug, an indication of an onset of analgesic-induced hyperalgesia, an indication of conditions of allodynia, a measurement of dose-response characteristics of pain management drugs, and a characterization of a pain condition.10-06-2011
20080319335SYSTEM AND METHOD FOR AUTOMATICALLY ADJUSTING DETECTION THRESHOLDS IN A FEEDBACK-CONTROLLED NEUROLOGICAL EVENT DETECTOR - Methods and systems for detecting neurological events and approximating a target detection rate are disclosed. A target detection rate may be identified for the neurological event. Electrographic signals incident on a neurological event detector may be monitored. Each signal may be compared to a threshold value for a parameter. As the threshold value varies, it has a predictable effect on a detection rate of the neurological event. A rate at which the electrographic signals exceed the threshold value may be measured and compared to the target detection rate. The threshold value may be adjusted to minimize the difference between the measured detection rate and the target detection rate.12-25-2008
20110034822SYSTEMS AND METHODS FOR MODULATING THE ELECTRICAL ACTIVITY OF A BRAIN USING NEURO-EEG SYNCHRONIZATION THERAPY - Described are methods, devices, and systems for a novel, inexpensive, easy to use therapy for treatment of coma, post-traumatic stress disorder, Parkinson's disease, cognitive performance, and/or amblyopia. Described are methods and devices to treat coma, post-traumatic stress disorder, Parkinson's disease, cognitive performance, and/or amblyopia that involves no medication. Methods and devices described herein use alternating magnetic fields to gently “tune” the brain and affect symptoms of coma, post-traumatic stress disorder, Parkinson's disease, cognitive performance, and/or amblyopia.02-10-2011
20110040202SENSORY-EVOKED POTENTIAL (SEP) CLASSIFICATION/DETECTION IN THE TIME DOMAIN - Techniques are disclosed for sensory-evoked potential (SEPs, e.g., visual-evoked potentials) signal detection/classification by synchronizing EEG to the repeated presentation of sensory stimuli in the time domain. In some embodiments, a system receives a plurality of EEG signal samples, generates a stimulus-locked EEG and determines whether the plurality of EEG signal samples are evoked in response to a pattern of stimulus. In some embodiments, no prior knowledge about the update pattern (such as the flashing frequency of a visual stimulus) of the stimulus and no prior knowledge about an individual user's EEG pattern are required.02-17-2011
20110245709SYSTEM AND METHOD OF ASSESSING ANALGESIC ADEQUACY USING BIOPOTENTIAL VARIABILITY - The system and method for predicting and measuring a subject's analgesic state and analgesic adequacy. Biopotential signals are obtained from a subject through electrodes. A processor will compute a measure that is representative of the subject's sedative state and/or muscle activity. A metric representative of such measures is then determined. In the case where a measure is taken of both the subject's sedative state and muscle activity the two measures are combined into an index representative of the subject's analgesic state and analgesic adequacy.10-06-2011
20110125047Method and system for monitoring physiological conditions - A method for providing an indication of a state of awareness for a patient, includes the steps of arranging data of an EEG and EMG power spectrogram to provide power versus frequency in a log-log arrangement; calculating a first best-fit line for a lower frequency region of the EEG power spectrogram; calculating at least a second best-fit line for a higher frequency region of the EEG power spectrogram. The display of these lines is augmented by displaying a template that identifies different regions on the display that help confirm the state of the patient. Secondly, the time domain EEG signals can be filtered and displayed such that different frequency bands can be simultaneously displayed or a single frequency band can be displayed according to different time scales.05-26-2011
20110125046METHODS AND APPARATUS FOR MONITORING CONSCIOUSNESS - The systems of the present invention provide improved accuracy in monitoring, analysing, detecting, predicting and/or providing alerts and alarms associated with depth of anaesthesia, depth of consciousness, hypnotic state, sedation depth, fatigue or vigilance of a subject, with as few as 3 surface electrodes. The systems incorporate real-time phase, amplitude and frequency analysis of a subject's electro-encephalogram. The systems weight outputs of various types of analyses to produce an integrated analysis or display for precise indication or alert to users of the systems including anaesthetists, nurses and other medical personnel, transport drivers and machine workers. The systems weight the outputs of one or more analysis algorithms including combinations of simultaneous, real-time R&K analysis, AEP spectral analysis-SEF-MF, Bi-coherence analysis, initial wave analysis, auditory response, arousal analysis, body movement analysis, 95% spectral edge analysis and anaesthetic phase and spectral energy variance measurement in association with a subject's state of consciousness.05-26-2011
20110213265IMPLANTABLE SEIZURE MONITOR - An implantable seizure monitor can include at least one sensing electrode and an electronics module configured to detect, record and/or log neurological events. For example, the electronics module can be configured to detect brainwaves indicative of seizures, such as, for example, epileptic seizures, and to create a log indicating when such seizures occur. The implantable seizure monitor can include a cushioning member made of a soft material and configured to be implantable between the epidermis and cranium of a patient.09-01-2011
20100222694FIELD-DEPLOYABLE CONCUSSION DETECTOR - A method and apparatus for providing an on-site diagnosis of a subject to determine the presence and/or severity of a concussion is provided. The method includes placing an electrode set coupled to a handheld base unit on the subject's head, acquiring brain electrical signals from the subject through the electrode set, processing the acquired brain electrical signals using a signal processing algorithm stored in a memory of the base unit, determining the presence and/or severity of a concussion from the processed signals, indicating the presence and/or severity of a concussion on the handheld base unit, and determining a course of treatment for the subject based on the indication.09-02-2010
20100217145Method of processing multichannel and multivariate signals and method of classifying sources of multichannel and multivariate signals operating according to such processing method - A method of processing multichannel and multivariate signals as described hereinbefore, wherein the signals from each channel are subjected to a first processing step by a recirculation artificial neural network being trained to generate the recorded multichannel and multivariate signals; and a second processing step in which the weights of the connections between the knots of the recirculation neural network determined in the first processing step are processed by an artificial neural network, the recirculation neural network being preferably of the non supervised kind. A particular family of recirculation neural network which can be used according to the present invention is a so called auto-associative neural network. The method further provides, in combination, the use of a predictive and/or classification and/or clustering algorithm for determining the qualities or features of objects from the multichannel multivariate signals generated by said object, the weight matrix obtained by processing said multichannel and multivariate signals with a self-associated neural network being used as records for representing said multichannel and multivariate signals. The method is used for patients suffering from neurological disorders for analysing and evaluating the EEG patterns of these patients.08-26-2010
20100217146METHOD AND SYSTEM FOR SLEEP STAGE DETERMINATION - A method and system for sleep stage determination is disclosed comprising: acquiring EEG data from two or more EEG electrodes of an electrode arrangement, wherein the EEG data is divided into one or more epochs; detecting graphoelements from the EEG data for each epoch using a graphoelement detector; calculating an entropy from the EEG data for each epoch in an entropy module; and, assigning a sleep stage to each epoch based on the calculated entropy and the detected graphoelements in a classifier module. This new method and system of sleep staging is potentially suited for, but not limited to, unattended sleep diagnostic scenarios.08-26-2010
20110087125SYSTEM AND METHOD FOR PAIN MONITORING AT THE POINT-OF-CARE - A method and apparatus for providing objective assessment of pain using a field portable device is described. The method includes placing an electrode set coupled to a handheld base unit on the subject's head, acquiring brain and/or peripheral nervous system electrical signals from the subject through the electrode set, processing the acquired brain electrical signals using a feature extraction algorithm stored in a memory of the base unit, classifying the processed signals into pain categories, determining an objective quantification of the pain level, and indicating the pain category and/or pain scale on the handheld base unit. The memory of the base unit stores a reference database for classification of the processed signals, or the base unit is configured to wirelessly access the reference database from a remote data storage unit.04-14-2011
20110245707PORTABLE STROKE MONITORING APPARATUS - A method for monitoring a patient to detect the onset of a stroke, the method executed at least in part by a control logic processor, obtains, from one or more electrodes on the patient's scalp, at least a first brain wave signal pattern and a second brain wave signal pattern from the patient. The system compares at least the first brain wave signal pattern to the second brain wave signal pattern and reports a stroke, storing, in an electronic memory, a record indicating the time of the stroke according to the comparison.10-06-2011
20090312664APPARATUS AND METHOD FOR OBTAINING EEG DATA - An apparatus for obtaining EEG data includes a signal processing component for receiving EEG signals from each of a plurality of electrodes and a data output component. The signal processing component is arranged to convert respective EEG signals in real time to a reduced data set and provide the reduced data set to the data output component.12-17-2009
20090312665MENTAL WORK LOAD DETECTOR AND MOTORCYCLE INCLUDING THE SAME - A mental work load detector arranged to sense the electroencephalogram of a person and estimate a mental work load on the perceptual-motor system and a mental work load on the perceptual-central processing system separately from each other includes a electroencephalogram sensor arranged to sense the electroencephalogram of a rider, an eye fixation-related potential detector arranged to detect an eye fixation-related potential by analyzing the electroencephalogram and to detect a lambda response, an event-related potential measuring device arranged to measure an event-related potential in response to a sound from a speaker and to detect auditory p300, a lambda response comparator arranged to determine whether the lambda response has decreased, an auditory p300 comparator arranged to determine whether the auditory p300 has decreased, and a mental work load determiner arranged to determine that the mental work load on the perceptual-central processing system has increased if the lambda reaction and the auditory p300 has decreased and that the mental work load on the perceptual-central processing system has increased if the auditory p300 has decreased but the lambda response has not decreased.12-17-2009
20090312663System and Method for Neurometric Analysis - A system, comprises a plurality of neurometric analyzing software modules operating on electroencephalogram (EEG) data, each module performing a defined task with respect to neurometric analysis of the EEG data and a database including normative neurometric data in combination with a server including an authorization module, the authorization module comparing data received from a remote user to determine whether the user is authorized to utilize any of the plurality of analyzing software modules and an analysis module configured to receive input data from a patient and select one of the neurometric analyzing modules based on the input data, wherein the selected one of the neurometric analyzing modules compares the input data to the normative neurometric data to generate an output, the analysis module selecting the one of neurometric analyzing modules from a set of subscribed neurometric analyzing modules.12-17-2009
20090082688LOCALISING AND DISPLAYING ELECTROPHYSIOLOGICAL SIGNALS - The invention provides a method and apparatus for acquisition and analysis of data that displays a linear relationship or can be transformed into a linearized relationship, such as electrophysiological signal data from sensors such as those suitable for EEG, MEG, ECG and the like. The method, which can be implemented in computer software, includes computing a current density vector field by solving the related unweighted linear inverse problem, pre-processing the current density vector field using an sLORETA transformation, computing a diagonal weighting matrix so that its entries are determined by a monotonically increasing function of their corresponding values in the sLORETA method outputs, and computing the current density vector field by solving the related weighted linear inverse problem. The outputs of the method can be stored in computer files for display on suitable monitors.03-26-2009
20110178421METHOD AND DEVICE FOR EVALUATING AN INTENSIVE EEG OR AN EEG DURING ANAESTHESIA - The invention relates to a method and a device for evaluating an intensive EEG or an EEG during anaesthesia, according to which time domain and/or frequency range parameters are determined from the EEG graphs (07-21-2011
20100076333METHODS AND APPARATUS FOR MONITORING CONSCIOUSNESS - The systems of the present invention provide improved accuracy in monitoring, analysing, detecting, predicting and/or providing alerts and alarms associated with depth of anaesthesia, depth of consciousness, hypnotic state, sedation depth, fatigue or vigilance of a subject, with as few as 3 surface electrodes. The systems incorporate real-time phase, amplitude and frequency analysis of a subject's electro-encephalogram. The systems weight outputs of various types of analyses to produce an integrated analysis or display for precise indication or alert to users of the systems including anaesthetists, nurses and other medical personnel, transport drivers and machine workers. The systems weight the outputs of one or more analysis algorithms including combinations of simultaneous, real-time R&K analysis, AEP spectral analysis-SEF-MF, Bi-coherence analysis, initial wave analysis, auditory response, arousal analysis, body movement analysis, 95% spectral edge analysis and anaesthetic phase and spectral energy variance measurement in association with a subject's state of consciousness. 03-25-2010
20100069776DIAGNOSING AND MONITORING NEUROLOGICAL PATHOLOGIES AND STATES - Certain embodiments of the present invention provide for the detection and monitoring of multiple micro-scale neurological signals indicative of neurological state, neurological activity, and/or neuropathology. By examining such micro-scale neurological signals, a care provider may make more accurate differential diagnoses, identify the most efficacious treatment strategy, and/or track the efficacy of treatment. In some embodiments, analysis of micro-scale electrophysiological signals can be used in the diagnosis, treatment decisions, and monitoring of several neurological disorders, e.g. epilepsy, movement disorders, and psychiatric disorders. In some embodiments, different cortical areas can be mapped, for example, to define boundaries between healthy and/or pathological neural tissue.03-18-2010
20110251511METHOD FOR PROCESSING A BRAIN WAVE SIGNAL AND BRAIN COMPUTER INTERFACE - Method and brain computer interface for processing a brain wave signal of a subject using a brain wave detector. One or more stimuli are applied to the subject which each include a pseudo random noise component. The brain wave signal is detected and mental processing of the one or more stimuli is tracked by correlating the pseudo random noise component and the brain wave signal.10-13-2011
20110098593Head Harness &Wireless EEG Monitoring System - An assembly and system for collection and assessment of physiological data is provided. The assembly includes a physiological data acquisition module that may be used in combination with a head harness for the collection, recordation, storage and transmission of quality physiological data. The assembly integrates easy to use, self-applied electrodes in a user-friendly system resulting in less data artifacts than commonly seen in conventional methods and techniques for collecting physiological data. The assembly and system captures high-quality physiological data for display, storage, processing and analysis.04-28-2011
20110077546System and Method for Applied Kinesiology Feedback - Applied kinesiology method and device utilizes an examiner's autonomic response to truth/false or beneficial/non-beneficial stimulus and provides immediate feedback to the examiner in the context of an applied kinesiology exam. Kinesiology glasses detect local pupillary response to truthfulness locally and remotely. Through measurements of the pupils dilation or constriction and processing of the measurements, the response is obtained and feedback, via sensory stimulation, is provided to the examiner that reflects the pupillary response. The device and method effectively eliminate the subjective components of prior art muscle testing response from the hands of the testing examiner.03-31-2011
20110060238Systems and methods for intra-operative physiological functional stimulation - Improved assemblies, systems, and methods provide safeguarding against tissue injury during surgical procedures and/or identify nerve damage occurring prior to surgery and/or verify range of motion or attributes of muscle contraction during reconstructive surgery. Embodiments of methods according to the present invention provide the ability to intra-operatively simulate post-operative physiologic function of a body part. Such methods may be used during various surgical procedures, including tendon transfer procedures. Included are one or more steps of confirming paralysis or a weakened condition of a body part, confirming responsivity or operability of transfer tissue to supplement the functionality of the paralyzed or weakened part, and intra-operatively simulating post-operative functionality of the transfer tissue to enhance and/or predict the outcome of the surgical procedure.03-10-2011
20110071416ELECTROENCEPHALOGRAM INTERFACE SYSTEM - An eyeglass-type electroencephalogram interface system is worn on the head of a user. The system includes: an output section for presenting a visual stimulation to the user; an ear electrode portion disposed at a position coming in contact with an ear of the user when the system is worn; a facial electrode portion disposed at a position coming in contact with the face below a straight line connecting an external canthus and an internal canthus of an eye of the user, such that the mass of the system is supported at the position, when the system is worn; and an electroencephalogram measurement and determination section for measuring an event-related potential on the basis of a potential difference between the ear electrode portion and the facial electrode portion based on the visual stimulation being presented by the output section as a starting point.03-24-2011
20080234597Monitoring Neuronal Signals - A monitoring device for monitoring an individual under investigation comprises a recording device for recording a neuronal signal from the individual, and a calculating device for calculating a parameter representing a quantitative measure of an anaesthesia or coma condition of the individual and being derived from the neuronal signal, wherein the calculating device is adapted for calculating a complexity parameter representing the quantitative measure of the anaesthesia or coma condition, and the calculating device includes a buffer circuit for storing at least one time series of the neuronal signal and an analysis circuit for subjecting the time series to a recurrence quantification analysis (RQA) providing the complexity parameter. Furthermore, a method includes estimating a parameter representing a quantitative measure of an anaesthesia or coma condition of an individual.09-25-2008
20100081958PULSE-BASED FEATURE EXTRACTION FOR NEURAL RECORDINGS - A neural recording system (04-01-2010
20120203130Tinnitus Therapy Device - The invention relates to a device for tinnitus therapy having an EEG device, particularly a Q-EEG device and a head piece having at least one applicator generating a low-frequency electromagnetic field in the frequency range 1-100 Hz and having a field strength below 20 mT.08-09-2012
20120203129Brain Machine Interface Device - A distributed real-time wireless neural interface including a reader and an array of distinct recording devices having a wireless section and a sensor section. The reader outputs and receives radio-frequency signals. The wireless section of the array includes an rf power converter, an antenna, a regulator, and a modulator. The antenna receives the radio-frequency signals output by the reader and provides the radio-frequency signals to the rf power converter which converts such radio-frequency signals to power signals. The regulator receives the power signals and regulates such power signals to provide stable power signals. The sensor section receives the stable power signals and is adapted to detect neural activity and provide output signals containing information indicative of such neural activity to the modulator. The modulator receives the power signals and the output signals from the sensor section communicates the information in the output signals to the reader via the antenna.08-09-2012
20110152708SYSTEM AND METHOD OF SPEECH SOUND INTELLIGIBILITY ASSESSMENT, AND PROGRAM THEREOF - A speech sound intelligibility assessment system includes: a biological signal measurement section for measuring an electroencephalogram signal of a user; a presented-speech sound control section for determining a speech sound to be presented by referring to a speech sound database retaining a plurality of monosyllabic speech sounds; an audio output section for presenting the speech sound determined by the presented-speech sound control section as an audio; a characteristic component detection section for utilizing the electroencephalogram signal of the user measured by the biological signal measurement section to determine presence or absence of a characteristic component of an event-related potential at 800 ms±100 ms from a point of presenting the audio; and a speech sound intelligibility assessment section for, based on a result of determination by the characteristic component detection section, determining whether the user has aurally comprehended the speech sound or not.06-23-2011
20110046504DISTRIBUTED NEURO-RESPONSE DATA COLLECTION AND ANALYSIS - Distributed mechanisms are provided for collecting neuro-response data from subjects exposed to the stimulus material in multiple settings. Stimulus material may include marketing and entertainment materials. Neuro-response data collection mechanisms such as Electroencephalography (EEG) and Electrooculography (EOG) are used to collect data from subjects in laboratory and corporate settings. Neuro-response data is transmitted over a network to a data analyzer. The neuro-response data is processed at the data analyzer and effectiveness data for the stimulus material is received.02-24-2011
20110046503DRY ELECTRODES FOR ELECTROENCEPHALOGRAPHY - An electroencephalography (EEG) system includes a dry electrode design having a jagged, angular, comb, etc. shaped support housing. Each dry electrode housing includes multiple electrodes where each electrode has multiple contacts for scalp placement with minimal interference from hair. Signals from individual contacts may be disregarded and each housing may provide one or more aggregated signals for data analysis. Each electrode may be placed in close proximity with neighboring electrodes as no conductive gel is required and may be attached to the scalp using straps, elastic cap, spring-type materials, tape, etc. The dry electrode design effectively measures bio-signals including neurological activity.02-24-2011
20110046502DISTRIBUTED NEURO-RESPONSE DATA COLLECTION AND ANALYSIS - Distributed mechanisms are provided for identifying stimulus material and collecting neuro-response data from subjects exposed to the stimulus material in a variety of environments. Neuro-response data collection mechanisms such as Electroencephalography (EEG), Electrooculography (EOG), eye tracking, and/or facial emotion encoding are used to collect data from subjects in environments such as home, work, and recreational settings. Cameras, audio recorders, video recorders, processors, etc., identify stimulus material the subject is exposed to. The data collected may be minimally or extensively processed prior to transmission to a neuro-response data analyzer.02-24-2011
20110160607QEED-Guided Selection and Titration of Psychotropic Medications - Data corresponding to brain electrical activity of a patient from a QEEG is processed to determine which brain activity data deviates from that of a normative profile. The deviant brain activity data is used to determine a brain state vector (BSV) in a multidimensional brain electrical signal space, wherein the orientation of the BSV indicates the nature of the deviation from a normal state and may be used to prescribe a medicine to the patient and wherein the length of the BSV quantifies the degree of abnormality exhibited by the patient and may indicate the dosage of the medicine to be prescribed to the patient.06-30-2011
20110257556SYSTEMS AND METHODS FOR QUANTITATIVELY CHARACTERIZING SLOW WAVE ACTIVITIES AND STATES IN SLEEP - A method for quantitative sleep characterization includes acquiring a surface electroencephologram (surf-EEG) signal from an individual by a probe, decomposing the surf-EEG signal into a plurality of intrinsic mode functions (IMFs) by a computer processor in communication with the probe, wherein the plurality of IMFs comprises a first group of IMFs and a second group of IMFs, calculating a ratio comprising an amplitude or power of at least one of the IMFs in the first group in the numerator and a corresponding amplitude or power of at least one of the IMFs in the second group in the denominator; and identifying a period in the surf-EEG waveform as slow wave sleep (SWS) if the ratio associated with the period is above a predetermined threshold.10-20-2011
20080243022SEIZURE PREDICTION USING BRAIN SIGNAL TELEMETRY - An ambulatory intrinsic brain signal processor circuit is coupled to a plurality of electrodes. The signal processor circuit can include a digital multiplexer circuit coupled to the electrodes to multiplex brain signal data from different electrodes together into a multiplexed data stream. An ambulatory transceiver circuit wirelessly communicates information to and from a remote transceiver. A controller circuit permits a user to control which of the electrodes contribute data, a data resolution, and whether the data includes one or both of neural action or local field potential data. Seizure prediction components and methods are also described.10-02-2008
20110087127MEASUREMENT FOR EEG REACTIVITY - The invention relates to a method and apparatus for assessing the reactivity observable in a certain physiological signal, especially the EEG signal, of a comatose subject. In order to obtain an objective and a reliable measure of the reactivity automatically and without the presence of a trained EEG specialist, a valid signal model is constructed for an EEG signal obtained from the subject. A time reference corresponding to a stimulus is applied and further signal data is obtained from the time series, the further signal data being subsequent to the time reference. By employing the further signal data, the method tests whether the signal model remains to be a valid signal model for the EEG signal also after the stimulus, and indicates, based on the test, whether reactivity is present in the physiological signal.04-14-2011
20110263999METHOD AND APPARATUS FOR DETECTION OF NERVOUS SYSTEM DISORDERS - Systems and methods for detecting and/or treating nervous system disorders, such as seizures. Certain embodiments of the invention relate generally to implantable medical devices (IMDs) adapted to detect and treat nervous system disorders in patients with an IMD. Certain embodiments of the invention include detection of seizures based upon comparisons of long-term and short-term representations of physiological signals. Further embodiments of the invention include preparing for the delivery of therapy by warming up therapy delivery components prior to the expected delivery of therapy.10-27-2011
20100292602SEIZURE FORECASTING, MICROSEIZURE PRECURSOR EVENTS, AND RELATED THERAPEUTIC METHODS AND DEVICES - A multiscale recording and stimulation system for identifying and responding to epileptiform activity. The system includes the use of microelectrode arrays (e.g., 10-100 micron electrodes with 100-500 micron spacing) to monitor iEEG activity of submillimeter regions or islands in the epileptogenic zone of brain tissue (e.g., independent microdomains in the range of 100-1000 micron diameter).11-18-2010
20110118620Method and system for monitoring and displaying physiological conditions - A method for providing an indication of a state of awareness for a patient, includes the steps of arranging data of an EEG and EMG power spectrogram to provide power versus frequency in a log-log arrangement; calculating a first best-fit line for a lower frequency region of the EEG power spectrogram; calculating at least a second best-fit line for a higher frequency region of the EEG power spectrogram. The display of these lines is augmented by displaying a template that identifies different regions on the display that help confirm the state of the patient. Secondly, the time domain EEG signals can be filtered and displayed such that different frequency bands can be simultaneously displayed or a single frequency band can be displayed according to different time scales.05-19-2011
20110118619METHODS AND APPARATUS FOR MONITORING CONSCIOUSNESS - The systems of the present invention provide improved accuracy in monitoring, analysing, detecting, predicting and/or providing alerts and alarms associated with depth of anaesthesia, depth of consciousness, hypnotic state, sedation depth, fatigue or vigilance of a subject, with as few as 3 surface electrodes. The systems incorporate real-time phase, amplitude and frequency analysis of a subject's electro-encephalogram. The systems weight outputs of various types of analyses to produce an integrated analysis or display for precise indication or alert to users of the systems including anaesthetists, nurses and other medical personnel, transport drivers and machine workers. The systems weight the outputs of one or more analysis algorithms including combinations of simultaneous, real-time R&K analysis, AEP spectral analysis-SEF-MF, Bi-coherence analysis, initial wave analysis, auditory response, arousal analysis, body movement analysis, 95% spectral edge analysis and anaesthetic phase and spectral energy variance measurement in association with a subject's state of consciousness.05-19-2011
20110118618Electronic Identity Card - A method comprises the steps of obtaining a baseline measurement corresponding to a representation of brain activity from a living body and storing the baseline measurements on a storage device configured to be wearable on the living body in combination with obtaining, at a time subsequent to the baseline measurement, a second measurement representing brain activity from the living body, reading the baseline measurement from the storage device and evaluating the living body based on a comparison of the second measurement to the baseline measurement. A system for analyzing electrical brain activity, the system comprises a component for reading, from a storage medium, data corresponding to a baseline measurement of brain activity of a living body and a component for determining data representing a current brain activity of the living body in combination with a component for evaluating the living body by comparing the baseline measurement data and the current brain activity data.05-19-2011
20100324441Brain-Related Chronic Pain Disorder Treatment Method and Apparatus - A method for treating brain-related chronic pain disorders in human subjects includes assessing the brain function of a subject suffering from chronic pain, diagnosing a chronic pain-related abnormal brain condition, and mitigating the abnormal brain activity by applying an electrical stimulation signal to tissues corresponding to at least one area of abnormal brain activity.12-23-2010
20100324440REAL TIME STIMULUS TRIGGERED BY BRAIN STATE TO ENHANCE PERCEPTION AND COGNITION - An approach is provided for real time stimulus triggered by brain state and includes receiving data that indicates a brain state and a set of one or more stimuli associated with the brain state. Onset of an instance of the brain state is detected in a subject. In response to detecting onset of the instance, application to the subject of a stimulus of the set is initiated before the instance ends. In some embodiments, the brain state is determined based on a range of values for a function of brain signal data, wherein the range of values is associated with desired performance in response to an associated stimulus. The approach can enhance performance, enhance learning or enhance the probing of impact of that state on perception, action or cognition.12-23-2010
20100121213SEIZURE DISORDER EVALUATION BASED ON INTRACRANIAL PRESSURE AND PATIENT MOTION - Intracranial pressure of a patient may be monitored in order to evaluate a seizure disorder. In some examples, trends in the intracranial pressure over time may be monitored, e.g., to detect changes to the patient's condition. In addition, in some examples, a seizure metric may be generated for a detected seizure based on sensed intracranial pressures. The seizure metric may indicate, for example, an average, median, or highest relative intracranial pressure value observed during a seizure, a percent change from a baseline value during the seizure, or the time for the intracranial pressure to return to a baseline state after the occurrence of a seizure. In addition to or instead of intracranial pressure, patient motion or posture may be monitored in order to assess the patient's seizure disorder. For example, a seizure type or severity may be determined based on patient motion sensed during a seizure.05-13-2010
20110087126Light-Proof Electrodes - According to principles of this invention, the photoelectrochemical effect (“PE effect”) may be greatly reduced or eliminated, even when an electrode is immersed in an electrolyte and exposed to light, by using a transparent conductor to record electrical activity. Thus, an electrode with a clear conductor may be used to accurately record electrical activity of neurons and other cells that are exposed to light in vivo or in vitro. Such an electrode eliminates or greatly reduces the artifacts that would otherwise be caused by light due to the PE effect.04-14-2011
20100113960Method and system for jointly monitoring physiological conditions - A method for providing an indication of a state of awareness for a patient, includes the steps of arranging data of an EEG and EMG power spectrogram to provide power versus frequency in a log-log arrangement; calculating a first best-fit line for a lower frequency region of the EEG power spectrogram; calculating a second best-fit line for a higher frequency region of the EEG power spectrogram; calculating a third best-fit line for the EMG power spectrogram; and displaying an indication of the state of awareness based on the first, second and third best-fit lines.05-06-2010
20100185113Coordinating System Responses Based on an Operator's Cognitive Response to a Relevant Stimulus and to the Position of the Stimulus in the Operator's Field of View - Neurophysiological responses such as EEG signals of brainwave activity, dilation signals of pupillary response, dwell time signals of eye movement and imaging signals of vascular response are monitored as a correlate of the operator's cognitive response. These responses are processed to determine if there is a significant cognitive response to a stimulus (visual or non-visual) to generate a positive cue. The operator's eye movement is monitored to determine when the operator fixates on the stimulus and the position of the stimulus in the operator's field-of view (FOV). The positive cue and position of the stimulus, and typically the time-stamp of the cue are output triggering a system response. The temporal sequence of cues and stimulus position may be processed to reinforce or reject the cue or refine the stimulus position.07-22-2010
20110152709MOBILE BODY CONTROL DEVICE AND MOBILE BODY CONTROL METHOD - A mobile body control device includes: a brain activity detecting unit that detects brain activity information of a user; a brain signal separating unit that separates an artifact component from the brain activity information detected by the brain activity detecting unit; a control signal generating unit that slides a sampling period for extracting brain data, at predetermined intervals in an overlapped manner in the brain activity information from which the artifact component is separated, successively calculates feature values for the brain data within each of the sampling periods obtained by sliding, and generates a control signal based on the feature values calculated; and a drive control unit that drives and controls a mobile body with a user riding thereon, based on the control signal generated.06-23-2011
20100030097METHOD TO DETERMINE THE ATTRIBUTES ASSOCIATED WITH A BRAND OR PRODUCT - A method of evaluating characteristics of a brand or product including the steps of: (a) presenting the brand or product to the subject during a first period; (b) determining brain activity of the subject during the first period; (c) presenting neutral visual and/or audio material to a subject during a second period; (d) determining a reference level of brain activity of the subject during the second period; and (e) evaluating attributes associated by the subject with the brand or product by determining differences in brain activities between the first and second periods.02-04-2010
20100022908System and Method for Interfacing Cellular Matter with a Machine - A system for interfacing cellular matter with a machine comprising a transponder implantable in cellular matter and configured to detect a first signal. The system also includes a receiver external to the cellular matter and configured to receive a second signal in response to the transponder detection of the first signal. A transmitter is also included in the system to transmit a third signal to a machine in response to the receiver receipt of the second signal.01-28-2010
20110218453Machine control device, machine system, machine control method, and recording medium storing machine control program - A machine control device includes: first decoders for estimating, from brain signal information, which one of body movements a user performs or images, based on learning using pairs of movements performed by the user and brain signal information, the body movements going toward one of first to nth body postures; second decoders for estimating from the brain signal information, an correct rate on the body movement estimation, based on learning using pairs of correct rates of the estimation of body movements and the brain signal information; and electric prosthetic arm control section for controlling an electric prosthetic arm to change stepwise its posture between first to nth postures via at least one intermediate posture therebetween, the first to nth postures corresponding to the first to nth body postures. The first decoders perform the estimation only when the estimated correct rate exceeds a threshold. When the first decoders estimate that the body movements goes toward a body posture different from the current one, the electric prosthetic arm control section changes the posture of the machine by performing a part of substeps of change from one of the first to nth body postures toward the posture associated with the body posture toward which the estimated body movement goes. This configuration allows a user to control a brain-signal-based machine to perform a natural movement without a long-term training and much brain information.09-08-2011
20100016751Quantitative EEG Method to Identify Individuals at Risk for Adverse Antidepressant Effects - Methods, apparatus, and systems are provided for efficiently and accurately identifying individuals at risk for adverse effects from psychotropic or CNS-active treatment. Changes in a brain activity indicator (e.g. EEG cordance) are used to predict the adverse effects of treatment based on an experimentally derived cutoff value. For example, a reliable biological indicator is provided with high predictive capability for identifying, very early in the course of treatment (e.g. <=48 hours after start of treatment), those individuals who are at greatest risk for worsening suicidality and other adverse effects of antidepressant drugs.01-21-2010
20080243021Signal Common Mode Cancellation For Handheld Low Voltage Testing Device - An apparatus for monitoring bioelectric signals of a patient which includes a processing system and an interface for receiving external electrical signals representative of a condition of the patient. The interface is configured to convey a representation of the received external signals to the processing system, and includes a common mode cancellation amplifier circuit which is adapted to reduce common mode signal noise present in the external signals.10-02-2008
20110306895BIOLOGICAL SIGNAL PROCESSING APPARATUS, BIOLOGICAL SIGNAL PROCESSING METHOD, AND BIOLOGICAL SIGNAL PROCESSING PROGRAM - A biological signal processing apparatus includes an obtaining unit that obtains a spectrum of a biological signal that has been obtained, a generation unit that generates a three-dimensional waveform by plotting elements of the spectrum obtained by the obtaining unit in a space defined by a time axis, a frequency axis, and an intensity axis, and a detection unit that detects a specified waveform component using a position along the intensity axis at which a cross-section of the three-dimensional waveform in a time-frequency domain generated by the generation unit is to be observed and a state of the cross-section at the position as criteria for recognition.12-15-2011
20090118635AUTOMATED 3D BRAIN ATLAS FITTING USING INTRA-OPERATIVE NEUROPHYSIOLOGICAL DATA - A method includes storing in memory preoperative brain atlas data. Neurophysiological data is obtained intra-operatively for a plurality of known sites in a brain of a given patient to provide corresponding intra-operative neurophysiological data for at least a portion of the sites. A constrained optimization is performed to fit the pre-operative brain atlas data based at least in part on the intra-operative neurophysiological data.05-07-2009
20090216146Method and System for Processing and Electroencephalograph (Eeg) Signal - The invention provides a method and system for locating an epileptic focus in an individual. In accordance with the method of the invention, an integer N of ictal EEG signals are obtained on the individual and a principal component analysis generating N output signals is executed on the ictal EEG signals. The epileptic focus s then located in a process involving one or more of the N output signals.08-27-2009
20120041330FIELD DEPLOYABLE CONCUSSION ASSESSMENT DEVICE - A device and method for assessment of traumatic brain injury (TBI) is described. The device is configured to acquire brain electrical signals from a patient's forehead using one or more neurological electrodes. The acquired brain electrical activity data is subjected to artifact rejection and feature extraction, and a subset of features are then combined in at least one classifier function. The classifier functions statistically place a patient in one of four categories related to the extent of brain dysfunction: 1) normal brain electrical activity; 2) abnormal brain electrical activity consistent with non-structural injury with less severe manifestations of functional brain injury; 3) abnormal brain electrical activity consistent with non-structural injury with more severe manifestations of functional brain injury; and 4) abnormal brain electrical activity consistent with structural brain injury.02-16-2012
20080306398BRAIN WAVE DETECTING APPARATUS - A brain wave detecting apparatus includes a plurality of brain wave detecting portions that are arranged on a side surface of a head and detect brain waves of the head, a selecting portion selecting one of the plurality of brain wave detecting portions on the basis of brain wave signals transmitted from the plurality of brain wave detecting portions, and a transmitting portion transmitting information about the brain wave signal transmitted from said one of the plurality of brain wave detecting portions.12-11-2008
20120046569METHOD AND APPARATUS - A method of providing cognitive training to a user, the method including, in a processing system, presenting a cognitive task to a user, the cognitive task requiring the user to view presented information and provide at least one input response; determining the at least one input response using an input device; determining from a measuring device a measure of electrical activity in the user's brain whilst performing the cognitive task; and, determining a score based on at least one of the at least one input response and the measured electrical activity.02-23-2012
20120010522INPUT CONVERTER FOR AN EEG MONITORING SYSTEM, SIGNAL CONVERSION METHOD AND MONITORING SYSTEM - In order to minimize noise and current consumption in an EEG monitoring system (01-12-2012
20120310106Device-independent neurological monitoring system - A system that analyzes neurological signals is described. During operation, the system monitors neurological signals from users at multiple locations, where the neurological signals are associated with different electrode configurations. Then, the system modifies the monitored neurological signals to correct for the different electrode configurations so that a resulting set of modified neurological signals corresponds to a common electrode configuration, thereby facilitating subsequent identification of a subset of the set of modified neurological signals.12-06-2012
20120310105MONITORING TASK ENGAGEMENT USING BETA OSCILLATIONS - The invention provides methods and apparatuses for monitoring task engagement by measuring beta frequency oscillations in the brain. Changes in power, frequency, and/or coherency of beta frequency oscillations correlate to an individual's engagement in or disengagement from a task. Accordingly, beta frequency oscillations can be used to determine if an individual prematurely disengages from a task, to diagnose if a person has a disorder affecting task engagement, and to evaluate the efficacy of a treatment for a disorder.12-06-2012
20100145216Neural Interface Assembly and Method For Making and Implanting The Same - An implant assembly for creating a neural interface with a central nervous system having at least one biocompatible intracortical electrode is presented along with a method of making and implanting device. The mechanical, electrical and biological characteristics of the assembly support its use as a reliable long term implant.06-10-2010
20110166471Patient Event Marking in Combination with Physiological Signals - Methods for receiving a patient mark in an implanted device. A patient may experience symptoms that indicative of a neurological event or are common precursors to more severe clinical symptoms. The patient may activate a patient activator. Activation of the patient activator can cause the patient activator to transmit the patient mark to an implanted device. The implanted device may adjust physiological data being stored in response to the patient mark, including data before and after the patient mark. The patient mark may be used to time tune the detection algorithms and otherwise tune the detection capability of the implanted device and may also be used as an aid in statistical analysis of the stored physiological data.07-07-2011
20120022391Multimodal Brain Computer Interface - Determining an intended action based on one more cortico-physiologies within brain signals includes establishing communication with one or more electrodes for sensing the brain signals of a subject, and concurrently receiving brain signals representative of a plurality of cortico-physiologies. The brain signals are transmitted to a processor for use in determining the intended action and controlling a device.01-26-2012
20120022392Correlating Frequency Signatures To Cognitive Processes - Determining an intended action based on one more brain signal frequencies includes establishing communication with one or more electrodes for sensing brain signals of a subject, and acquiring the brain signals via the electrodes while the subject performs at least one cognitive task, wherein the acquired brain signals having a plurality of frequencies associated therewith. A physiologic change at one or more of the plurality of frequencies may then be identified from the acquired brain signals, and the one or more of the plurality of frequencies are associated with the cognitive task.01-26-2012
20110082381Time Frequency Transformation Analysis for Detection and Quantification of Epileptiform Activity Load in Generalized Epilepsies - Methods for detecting absence seizures are provided. An electroencephalogram (EEG) recording from a patient can be analyzed using an algorithm. The algorithm can include wavelet transform, in which wavelets can extract an original signal into scales that can be mapped into different pseudofrequencies. The algorithm can also include a sliding variance technique (SVT).04-07-2011
20120059273PROCESS AND DEVICE FOR BRAIN COMPUTER INTERFACE - A brain computer interface as an alternative communication channel to be used in various applications, such as robotics. In one embodiment of the invention, there is provided a process for the analysis and conversion of EEG signals obtained from the brain into movement commands through electric and/or mechanical devices. The process of the present invention provides substantial advantages over the similar systems/techniques known in the art, such as a 91% average hit rate, obtained in attempts to control a mobile robot. In other embodiment of the invention, there is provided an apparatus comprising: means for obtaining brain signals; an electroencephalograph (EEG); and means for transducing said signals into functional commands useful in several applications. Said means for transducing mental signals is the core of the invention and provides a number of technical advantages over the similar systems/techniques known in the art of identifying mental activities.03-08-2012
20090137922METHOD FOR ANTI-STRESS TRAINING - The method is for reducing a stress level of a user. The user is provided with a sensor (05-28-2009
20120065536SYSTEM AND METHOD FOR NEUROLOGICAL EVALUATION - A device and method for acquiring and processing a patient's brain electrical activity is provided. Noise contamination during acquisition and transmission of the brain electrical signals is reduced by providing differential amplifiers in the patient sensor in close proximity to the electrodes. A guarding technique is applied in the patient sensor to avoid inductive coupling of low frequency environmental noise. Radio-frequency (RF) filters and a Faraday cage assembly are also provided in the patient sensor to reduce electromagnetic interference. The brain electrical signals acquired by the electrodes are transmitted through shielded cables to a handheld base unit for signal processing.03-15-2012
20120157873WAKE-UP DEVICE FOR NAPPING TIME - A wake-up device, used for awaking a user in a nap or a short-term sleep, includes an electroencephalogram (EEG) sensor, a processing module and a wake-up module. The EEG sensor is disposed on the user's head for sensing an EEG signal from the user. The processing module is coupled with the EEG sensor, and receives and processes the EEG signal. If the user is determined in the sleep stage 06-21-2012
20120065537SYSTEM FOR IN VIVO DETECTION OF A FUNCTIONAL AREA OF THE HUMAN BRAIN LEADING TO A HEMISPATIAL NEGLECT SYNDROME IN CASE OF LESION - A system for detecting a functional area (03-15-2012
20110092842IMPLANTABLE NEURAL SIGNAL ACQUISTION APPARATUS - In an embodiment, an implantable neural signal acquisition apparatus includes a plurality of electrodes, an implantable electronics package, and a wire bundle. The electrodes are configured to be subcutaneously implanted within neural tissue of a test subject and to collect analog neural signals from the test subject. The implantable electronics package is configured to be subcutaneously implanted within the test subject and to convert the analog neural signals to digital output. The wire bundle is coupled between the electrode array and the implantable electronics package and is configured to convey the analog neural signals from the electrodes to the implantable electronics package.04-21-2011
20120071780Method and a System for Classifying Neural Signals, and a Method of Selecting Electrodes for Direct Neural Control - A classification method for classifying neural signals, the method comprising the following steps: 03-22-2012
20120071779METHOD, APPARATUS AND COMPUTER PROGRAM PRODUCT FOR AUTOMATIC SEIZURE MONITORING - Method, apparatus and computer program product for monitoring seizure activity in brain are disclosed. At least one parameter set sequence is derived from brain wave signal data obtained from a subject, wherein each parameter set sequence comprises sequential parameter sets and each parameter set comprises values for at least two signal parameters, the values being derived from the brain wave signal data. A path formed by each of the at least one parameter set sequence in a parameter space is determined, thereby to obtain at least one path. The parameter space is defined by the at least two signal parameters. At least one evolution indicator is calculated, each evolution indicator quantifying the evolution occurred in respective path formed in a given time period in the parameter space. The at least one evolution indicator is then employed to produce an indication of seizure activity in the brain wave signal data.03-22-2012
20110066065SYSTEMS AND METHODS TO IDENTIFY A SUBGROUP OF ADHD AT HIGHER RISK FOR COMPLICATING CONDITIONS - This invention is directed to embodiments of systems and methods to identify a subgroup of ADHD at higher risk for complicating conditions that, for example, may be of concern to an ADHD evaluation, may account for attention and behavior symptoms, and may lead a clinician to exclusion of ADHD from primary diagnosis. In one embodiment, a method for identifying a subgroup of attention deficit hyperactivity disorder (ADHD) patients at higher risk for complicating conditions is provided. The method can include receiving, from a user or clinician, evaluation data associated with a plurality of patients identified with ADHD as a primary diagnosis; obtaining EEG data for each of the plurality of patients; determining, based at least in part on the EEG data, an indicator of ADHD, wherein the indicator supports a positive or negative ADHD evaluation; correlating the indicator with a user's or clinician's evaluation data; and based at least in part on the correlation, determining at least one subgroup of the plurality of patients, wherein the correlation provides positive support for diagnosis of ADHD or provides support for further testing for complicating conditions before proceeding with diagnosis of ADHD in at least one patient within the at least one subgroup.03-17-2011
20110105939CLASSIFICATION OF SEMATOSENSORY EVOKED POTENTIAL WAVEFORMS - Embodiments are disclosed relating to classification of sematosensory evoked potential waveforms.05-05-2011
20110105937ANALYSIS OF CONTROLLED AND AUTOMATIC ATTENTION FOR INTRODUCTION OF STIMULUS MATERIAL - A system analyzes neuro-response measurements including regional electroencephalography (EEG) measurements from subjects exposed to stimulus materials to determine locations in stimulus materials eliciting controlled attention and automatic attention. Additional stimulus materials are inserted into locations having salient attention attributes. In some examples, a challenging task is used to direct controlled attention onto a location and additional stimulus material is subtly presented in the location to benefit from automatic attention and salient attention measurements.05-05-2011
20110105938BINAURAL BEAT AUGMENTED BIOFEEDBACK SYSTEM - A biofeedback system that incorporates binaural beat technology to augment the EEG feedback provided to the trainee. Specifically, the system will provide binaural beats at the frequency of the brain's naturally occurring peak energy in the EEG band or bands subject to the biofeedback.05-05-2011
20100094154METHOD FOR ANALYZING FUNCTION OF THE BRAIN AND OTHER COMPLEX SYSTEMS - A method and system are provided for analyzing electromagnetic brain signals such as EEG and ECoG signals in a subject in real time and which avoids the need for time-intensive retrospective analysis of brain activity in the subject. This can be applied to all complex systems with multiple fluctuating signals to identify and predict significant events04-15-2010
20100094155System and Method for Prediction of Cognitive Decline - A system and method for prediction of cognitive decline, comprises an input receiving input data corresponding to brain activity of an individual and a processor coupled to the input for analyzing the input data to obtain a selected set of features, the processor comparing the selected set of features to at least a portion of entries in a database corresponding to brain activity of a plurality of individuals, wherein entries in the database have been separated into a plurality of categories corresponding to one of a degree of cognitive decline and a propensity for future cognitive decline of individuals relating to the entries, the processor determining, based on the comparison, a category most closely corresponding to the selected set of features.04-15-2010
20120123290EEG MONITORING SYSTEM AND METHOD OF MONITORING AN EEG - An EEG monitoring system (05-17-2012
20120123289SYSTEM AND METHOD FOR WIRELESS TRANSMISSION OF NEURAL DATA - Embodiments of the invention generally relate to a neuralphysiological data acquisition system configured to wirelessly transmit neural data from a patient to a receive subsystem. In an embodiment, a neuralphysiological data acquisition system includes a plurality of electrodes, a headstage, and a wireless module. The electrodes are configured to be implanted subcutaneously within neural tissue of a patient and to collect analog neural data from the patient. The headstage is coupled to the electrodes, and configured to receive and convert the analog neural signals to digital output. The wireless module is coupled to the headstage and configured to wireless transmit a signal representing the digital output to a receive subsystem including a wireless receiver.05-17-2012
20120220890DETECTING AND TREATING NERVOUS SYSTEM DISORDERS - Some embodiments of a mapping device may be capable of passing through cerebral veins and other cerebrovascular spaces to provide electrophysiological mapping of the brain. These embodiments of the device may also be capable of providing, simultaneously or separately, ablation energy or other treatments to targeted brain tissue. In such circumstances, a user may be enabled to analyze an electrophysiological map of a patient's brain and, at the same time or within a short time period before or after the mapping process, may be enabled to apply ablation energy for treatment of a central nervous system disorder. Such treatment may be accomplished without the use of invasive surgery in which the brain is accessed through an opening in the patient's cranium.08-30-2012
20120220889EEG CONTROL OF DEVICES USING SENSORY EVOKED POTENTIALS - An EEG control of devices using Sensory Evoked Potentials (SEPs) (e.g., visually-evoked potentials), is disclosed. In some embodiments, a system receives a plurality of EEG signal samples; generates a stimulus locked average signal using the plurality of EEG signal samples; and determines whether the plurality of EEG signal samples are evoked in response to a pattern of stimulus.08-30-2012
20100204604BRAIN FUNCTION MONITORING AND DISPLAY SYSTEM - A process for analysing an electroencephalogram signal representative of activity of a brain, including: i) generating coefficient data for a signal representation of a portion of the signal; ii) generating pole data representing positions of one or more poles on a complex plane, the positions being generated based on the coefficient data; and iii) generating, based on a mean position of the poles, brain state data representing functional state of the brain.08-12-2010
20120136273APPARATUS AND METHOD FOR MONITORING AND ANALYZING BRAINWAVES - A neurological monitoring and analysis system comprising electrodes disposable on a patient's head to detect neurological activity, an electrode retention device for securely retaining the electrode(s) on the patient's head and a warning alert device for providing a warning signaling that a particular neurological activity incident has occurred within the patient's brain. Additionally, the system comprises a computer based processing system operable to execute a brainwave diagnostic program to receive the neurological activity data from the electrode(s), analyze the received neurological activity data to identify an occurrence of the particular neurological activity incident, and transmit an activation signal to the warning alert device such that the warning alert device produces an observable notification indicating that the particular neurological activity incident has occurred.05-31-2012
20110184307 SYSTEM FOR SYNCHRONISING EEG WITH AUXILIARY OUTPUT, IN PARTICULAR VIDEO - A system for monitoring a patient's EEG output comprises an EEG recorder operative to generate an EEG output indicative of electrical activity produced by the brain of a patient, and an auxiliary recorder operative to generate an auxiliary output indicative of another characteristic of the patient. The auxiliary recorder may comprise a video recorder. An electronic data processor is operative to receive the EEG recorder output and the auxiliary output, the system being operative to generate synchronisation data indicative of when the EEG output and when the auxiliary output occurred with reference to a datum signal. The electronic processor is operative to process the synchronisation data to subsequently synchronise the playback of the EEG output with the auxiliary output. A compensation factor accounts for transmission latency.07-28-2011
20110184305EEG ANALYSIS SYSTEM - A process for analysing an electroencephalogram signal representative of activity of a brain, including: i) generating coefficient data for a signal representation of a portion of said signal; ii) generating first gain data representing an average amplitude of an output signal generated based on said signal representation and said coefficient data; iii) generating second gain data representing an average amplitude of said portion; and iv) generating, based on said first gain data and said second gain data, brain state data representing subcortical activity of said brain.07-28-2011
20130184603METHOD AND DEVICE FOR MULTIMODAL NEUROLOGICAL EVALUATION - A method of building classifiers for multimodal neurological assessment is described. The method comprises the steps of extracting quantitative features from a plurality of physiological and neurocognitive assessments, and selecting a subset of features from the extracted pool of features to construct multimodal classifiers. A device for performing point-of-care multimodal neurological assessment is also described.07-18-2013
20120083708ADAPTIVE REAL-TIME SEIZURE PREDICTION SYSTEM AND METHOD - A real-time seizure prediction system. The system includes an implantable electrode configured to transmit an analog neuro-electrophysiological signal from a subject, an analog-to-digital converter configured to convert the analog neuro-electrophysiological signal to a digital neuro-electrophysiological signal based on a predetermined sampling rate, a processor configured to perform following steps during a period defined by the predetermined sampling rate: calculate a plurality of autocorrelation coefficients of the digital neuro-electrophysiological signal for a first predetermined number of samples, calculate a predicted future value of the digital neuro-electrophysiological data based on the plurality of autocorrelation coefficients and the first predetermined number of samples of the digital neuro-electrophysiological data, compare the predicted future value with an actual future value of the digital neuro-electrophysiological data to determine a prediction error, calculate a threshold based on a mean squared value of the prediction error for the first predetermined number of samples and based on a proportionality constant, generate a seizure prediction signal if the prediction error remains above the threshold for a second predetermined number of samples, and a warning device configured to receive the seizure prediction signal and generate an alert.04-05-2012
20120172744ELECTROENCEPHALOGRAM MEASUREMENT APPARATUS, METHOD OF ESTIMATING ELECTRICAL NOISE, AND COMPUTER PROGRAM FOR EXECUTING METHOD OF ESTIMATING ELECTRICAL NOISE - An electroencephalogram measurement apparatus includes: an electroencephalogram measurement section for measuring an electroencephalogram of a user by using a plurality of electrodes; an electro-acoustic transducer for presenting an acoustic signal to the user, the electro-acoustic transducer being in a vicinity of at least one electrode among the plurality of electrodes while the electroencephalogram measurement section is worn by the user; an amplitude envelope extraction section for extracting an amplitude envelope of the acoustic signal presented by the electro-acoustic transducer; a frequency analysis section for applying a frequency analysis to the amplitude envelope extracted by the amplitude envelope extraction section; and a noise estimation section for estimating an electrical noise which is mixed at the at least one electrode by using a previously provided set of transform rules and the extracted amplitude envelope.07-05-2012
20120172743COUPLING HUMAN NEURAL RESPONSE WITH COMPUTER PATTERN ANALYSIS FOR SINGLE-EVENT DETECTION OF SIGNIFICANT BRAIN RESPONSES FOR TASK-RELEVANT STIMULI - The human neural response is coupled with computer pattern analysis for robust single-event detection of significant non-stationary brain responses triggered upon occurrence of a task-relevant stimulus. Classifier performance is enhanced fusing together the outputs of multiple different classifiers albeit multiple spatial classifiers to extract a temporal pattern as the brain response evolves, time and frequency-based spatio-temporal classifiers, and/or EEG and pupillary classifiers.07-05-2012
20100049074CATEGORIZING SONGS ON A PHYSIOLOGICAL EFFECT02-25-2010
20100049075Method and apparatus for monitoring eye tremor - An apparatus consistent with the present invention comprises a sensor for receiving a signal representing eye tremor and a processor for monitoring eye tremor while receiving the signal. A method consistent with the present invention includes receiving a signal representing eye tremor, comparing the received signal representing eye tremor to at least one reference value, and classifying a patient's brain stem function using the comparison of the received signal representing eye tremor to at least one reference value. An embodiment consistent with the present invention includes an ocular micro tremor (OMT) sensor and associated signal processing hardware and software for clinical analyses.02-25-2010
20100121215SEIZURE DETECTION ALGORITHM ADJUSTMENT - A medical system implements a seizure detection algorithm to detect a seizure based on a first patient parameter. The medical system monitors a second patient parameter to adjust the seizure detection algorithm. In some examples, the medical system determines whether a seizure for which therapy delivery is desirable occurred based on a second patient parameter. If a target seizure occurred, and the seizure detection algorithm did not detect the target seizure, the medical system adjusts the seizure detection algorithm to detect the target seizure. For example, the medical system may determine a first patient parameter characteristic indicative of the target seizure detected based on the second patient parameter and store the first patient parameter characteristic as part of the seizure detection algorithm. In some examples, the first patient parameter is an electrical brain signal and the second patient parameter is patient activity (e.g., patient motion or posture).05-13-2010
20120179062Electrode Applicator - An applicator for applying an electrode to a patient, and a system for recording of the electroencephalographic potential, the evoked potential, and the ground and reference potentials in electroenceophalographic and evoked potential measurements, is disclosed herein. The applicator includes a main body and a plunger unit.07-12-2012
20100274153Method and apparatus for reducing noise in brain signal measurements - A method and apparatus for reducing noise in brain signal measurements. The method provides an array of sensors providing for spatial oversampling, and multiple samplings over time to produce measurement data. The measurement data have a variance common to the sensors, and a remaining variance that can be safely assumed to be sensor or channel specific noise and that is accounted for by a suitable modification of the measurement data. The apparatus provides clusters of the sensors positioned in correspondence to the vertices of substantially equilateral triangles that are defined by tensile elements connecting the clusters.10-28-2010
20100010365Apparatus for analyzing brain wave - To increase intensity of the brain wave signal for detection. Provided is an apparatus for analyzing a brain wave which is installed on a vehicle comprising: a detection unit for detecting the brain wave signal, and separating and analyzing the detected brain wave signal; a discrimination unit for generating a control signal according to an intensity of the brain wave signal analyzed by the detection unit; a processing control unit for controlling subsequent processing according to a type of each of the plurality of control signals produced by the discrimination unit; at least one brain wave signal induction unit for generating a graphic inducing a predetermined type of the brain wave; and a display for displaying the generated graphic according to the received signal from the brain wave signal induction unit.01-14-2010
20100010364DEVICE FOR AMBULATORY MONITORING OF BRAIN ACTIVITY - A device for ambulatory monitoring of brain activity includes a patch secured to a head of a monitoring subject and an electrode secured to the head of the monitoring subject. The electrode produces a signal indicating brain activity of the monitoring subject. The device further includes a signal processor that receives the signal produced by the electrode and processes the signal to produce data. The signal processor is secured to the monitoring subject. The device further includes a display that displays the data produced by the signal processor, the display being secured to the monitoring subject. The device also includes a power source secured to the monitoring subject, the power source providing power to the electrode, the signal processor, and the display wherein the monitoring subject may ambulate unimpeded by the patch, the electrode, the signal processor, the display and the power source.01-14-2010
20100130882APPARATUS, METHOD AND PROGRAM FOR ADJUSTING DISTINCTION METHOD FOR ELECTROENCEPHALOGRAM SIGNAL - The electroencephalogram distinction method adjustment apparatus is used for adjusting a distinction method in an electroencephalogram interface section which™ is provided in an electroencephalogram interface system. The apparatus includes a category determination section and a distinction method adjustment section. The category determination section prestores reference data for classifying a characteristic feature of an electroencephalogram signal, and determines which one of a plurality of classified categories the measured electroencephalogram signal belongs to by using the reference data and a characteristic amount which is common to electroencephalogram signals with respect to two or more options presented by the output section. Based on the result of categorization, the distinction method adjustment section adjusts the distinction method for an electroencephalogram signal with respect to the option selected by the user.05-27-2010
20120253219Methods for Recommending Neurophysiological Disorder Therapy - Neurophysiologic information such as quantitative electroencephalography (QEEG) is used in a method for classifying, diagnosing, and treating physiologic brain imbalances. Neurophysiologic information is also used to guide sample selection in clinical tests for psychopharmacologic drug candidates. Finally, neurophysiologic information is used for remotely assessing and treating patients with physiologic brain imbalances.10-04-2012
20120253220Methods and Systems for Determining Optimum Wake Time - A system for determining optimum wake time is disclosed whereby the system comprising includes a receiver for receiving electroencephalogram (EEG) data. The system further includes a processor configured to generate at least one frequency band based on the EEG data received, wherein the processor is further configured to determine an optimum wake time based on a relative low point on the at least one frequency band. The system also includes an indicator configured to provide notification of the optimum wake time.10-04-2012
20120191000ELECTROENCEPHALOGRAM MEASUREMENT SYSTEM, ELECTROENCEPHALOGRAM MEASUREMENT METHOD, AND PROGRAM THEREOF - An exemplary electroencephalogram measurement system includes: a frequency analysis section for, analyzing a frequency power of the electroencephalogram signal of a user with respect to each set of a reference electrode and a measurement electrode; an insufficient electrode determination section for, through comparison of the analyzed frequency power against a first threshold value, distinguishing whether a state of attachment of each electrode is sufficient or not; and an insufficiency cause estimation section for determining the number of insufficient electrodes distinguished as insufficiently worn, determining a position at which each insufficient electrode is in contact with the user, and estimating a cause for the insufficient state of attachment of the insufficient electrode or electrodes that corresponds to the determined number of insufficient electrodes and position of each insufficient electrode by referring to insufficiency pattern data.07-26-2012
20090018462Neurologic System and Associated Methods - The present invention includes systems and methods for assessing stimulatory effects on a neurologic system. One method may include steps of stimulating the neurologic system, monitoring at least one neurologic state for effects of the stimulation to the neurologic system, gathering multi-dimensional data from the monitoring of the at least one neurological state, and analyzing the multi-dimensional data to determine multi-dimensional interactions between the stimulation and the effects on the at least one neurological state. Various neurologic states are considered to be within the scope of the present invention, including, without limitation, hypnotic, analgesia, relaxation, stress, depression, anxiety, allostasis, immune response, and combinations thereof.01-15-2009
20110125048METHOD FOR ASSESSING BRAIN FUNCTION AND PORTABLE AUTOMATIC BRAIN FUNCTION ASSESSMENT APPARATUS - A method and apparatus for performing rapid brain assessment may provide emergency triage to head trauma patients by analyzing a combination of spontaneous and evoked brain potentials. The spontaneous and evoked potentials are analyzed, and the results classified, to present a real-time assessment of a patient's brain, diagnosing any potential abnormalities therein.05-26-2011
20100331717Seizure Sensing and Detection Using an Implantable Device - A system and method for detecting and predicting neurological events with an implantable device uses a relatively low-power central processing unit in connection with signal processing circuitry to identify features (including half waves) and calculate window-based characteristics (including line lengths and areas under the curve of the waveform) in an electrographic signal received from a patient's brain. The features and window-based characteristics are combinable in various ways according to the invention to detect and predict neurological events in real time, enabling responsive action by the implantable device.12-30-2010
20110004116Implantable Seizure Monitor - An implantable seizure monitor can include at least one sensing electrode and an electronics module configured to detect, record and/or log neurological events. For example, the electronics module can be configured to detect brainwaves indicative of seizures, such as, for example, epileptic seizures, and to create a log indicating when such seizures occur. The implantable seizure monitor can include a cushioning member made of a soft material and configured to be implantable between the epidermis and cranium of a patient.01-06-2011
20110004115FUNCTIONAL ANALYSIS OF NEUROPHYSIOLOGICAL DATA - A method for functional analysis of neurophysiological data by decomposing neurophysiological data and EEG signal to form a plurality of signal features. The signal features may then optionally be analyzed to determined one or more patterns.01-06-2011
20100234752EEG control of devices using sensory evoked potentials - An EEG control of devices using Sensory Evoked Potentials (SEPs) (e.g., visually-evoked potentials), is disclosed. In some embodiments, a system receives a plurality of EEG signal samples; generates a stimulus locked average signal using the plurality of EEG signal samples; and determines whether the plurality of EEG signal samples are evoked in response to a pattern of stimulus.09-16-2010
20080269629Multimodal therapeutic and feedback system - The generation of alpha waves in a mammalian subject may be stimulated through a process of measuring a wave-from produced by the electrical activity of the subject's brain, analyzing the wave-form to determine changes in its frequency, and delivering audio and visual stimulation to the subject, each at a rate selected to vary the frequency of the wave-form until any alpha state is achieved. The rate may be selected by the subject, by a therapist, or may be varied automatically through a feedback mechanism.10-30-2008
20120330178METHOD AND APPARATUS FOR MULTIMODAL MOBILE SCREENING TO QUANTITATIVELY DETECT BRAIN FUNCTION IMPAIRMENT - A method and apparatus including a mobile device for administering and quantitatively determining a Risk Index that a user has suffered an impairment of brain function.12-27-2012
20110282231MECHANISMS FOR COLLECTING ELECTROENCEPHALOGRAPHY DATA - Efficient and effective mechanisms for collecting electroencephalography (EEG) data are provided to allow neuro-response data collection for in situ engagement monitoring and tracking. An EEG headset includes multiple point electrodes individually isolated and amplified. In some examples, multiple left side scalp electrodes exert forces that counterbalance forces from multiple right side scalp electrodes to secure the headset to allow front electrodes and rear electrodes to contact the scalp. Electrodes are arranged to avoid contact with the temporal region. The headset can be configured to perform processing while supporting both continuous input and output.11-17-2011
20110282230NEURODIAGNOSTIC MONITORING AND DISPLAY SYSTEM - A process for analysing an electroencephalogram (EEG) signal representative of activity of a brain of a subject, including: (i) generating coefficient data for a signal representation of a portion of the EEG signal; (ii) generating, based on the coefficient data, cortical state data representing the brain's receptivity to subcortical input and input from other areas of cortex; (iii) generating cortical input data representing a level of subcortical input to the brain at a time corresponding to the portion of the EEG signal; (iv) generating, based on the cortical state data and the cortical input data, display data representing the functional state of the brain of the subject; and (v) displaying the display data on display means.11-17-2011
20110319785Implantable Systems and Methods for Identifying a Contra-ictal Condition in a Subject - Systems and methods of monitoring a subject's neurological condition are provided. In some embodiments, the method includes the steps of analyzing a physiological signal (such as an EEG) from a subject to determine if the subject is in a contra-ictal condition; and if the subject is in a contra-ictal condition, providing an indication (e.g., to the subject and/or to a caregiver) that the subject is in the contra-ictal condition. The systems and methods may utilize a minimally invasive, leadless device to monitor the subject's condition. In some embodiments, if the subject is in a pro-ictal condition, the method includes the step of providing an indication (such as a red light) that the subject is in the pro-ictal condition.12-29-2011
20110319784EMOTIONAL STATE DETERMINING APPARATUS - An emotional state determining apparatus capable of determining an emotional state of a subject without reducing determination accuracy even if the number of brain wave signals to be used is reduced. A multifractal dimension computing section 12-29-2011
20120101402 METHOD AND SYSTEM FOR CONTROLLING A DEVICE - A method for controlling a device, the method including the steps of, in a processing system: receiving a signal associated with a thought pattern (04-26-2012
20120101401METHOD FOR THE REAL-TIME IDENTIFICATION OF SEIZURES IN AN ELECTROENCEPHALOGRAM (EEG) SIGNAL - The present invention relates to a method for the real-time identification of seizures in an Electroencephalogram (EEG) signal. The method provides for patient-independent seizure identification by use of a multi-patient trained generic Support Vector Machine (SVM) classifier. The SVM classifier is operates on a large feature vector combining features from a wide variety of signal processing and analysis techniques. The method operates sufficiently accurately to be suitable for use in a clinical environment. The method may also be combined with additional classifiers, such a Gaussian Mixture Model (GMM) classifier, for improved robustness, and one or more dynamic classifiers such as an SVM using sequential kernels for improved temporal analysis of the EEG signal.04-26-2012
20120289854BRAIN ACTIVITY MEASURING APPARATUS, BRAIN ACTIVITY MEASURING METHOD, BRAIN ACTIVITY DEDUCING APPARATUS, BRAIN ACTIVITY DEDUCING METHOD, AND BRAIN-MACHINE INTERFACE APPARATUS - What is provides is a brain activity deducing apparatus, a brain activity deducing method, a brain activity measuring apparatus, a brain activity measuring method, and a brain-machine interface device, capable of deducing a brain activity signal of a source subject. The information presentation device presents perceptible information to the first subject. The brain activity measurement device acquires a brain activity signal representing a brain activity of the first subject. The individual conversion device deduces a brain activity signal of the second subject from the acquired brain activity signal based on the individual conversion information, which correlates the brain activity signal of the first subject and the brain activity signal of the second subject.11-15-2012
20130012829METHOD FOR CONTROLLING DISPLAY APPARATUS USING BRAIN WAVE AND DISPLAY APPARATUS THEREOF - A display apparatus is controlled using brain waves. Brain wave information of a user is obtained and compared with pre-stored brain wave information previously mapped to control signals. A control signal corresponding to the brain wave information is generated, and the display apparatus is controlled according to the generated control signal. As a result, a user may control a display apparatus more conveniently and the display apparatus may provide various beneficial applications that take advantage of the capture of the brain wave information.01-10-2013
20120150059Arrangement and Method for Detecting Inconsistencies and Abnormalities in a Body - A system for detecting abnormalities or inconsistencies and a method to utilize the same are provided. In particular, a computer system may be adapted to detect the abnormality or inconsistency within at least a portion of a subject by generating internal impedance data which indicates that an impedance change within the portion of the subject has occurred. For example, the impedance change may be associated with a change in at least one characteristic of a blood vessel within the subject (such as a change in a fluid flow rate within at least a portion of the subject), a change in a fluid volume within at least a portion of the subject, etc. The impedance change also may be associated with the presence of a foreign object within the portion of the subject. In an exemplary embodiment, it is possible to detect the abnormality or inconsistency within the subject by generating a continuous, real time internal impedance map indicating the impedance change within the subject. Alternatively, the abnormality or inconsistency may be detected within the subject by generating a plurality of static internal impedance maps which indicate that the impedance change within the subject has occurred.06-14-2012
20100168604Processing for Multi-Channel Signals - Method and apparatus for improved processing for multi-channel signals. In an exemplary embodiment, an anomaly metric is computed for a multi-channel signal over a time window. The magnitude of the anomaly metric may be used to determine whether an anomaly is present in the multi-channel signal over the time window. In an exemplary embodiment, the anomaly metric may be a condition number associated with the singular values of the multi-channel signal over the time window, as further adjusted by the number of channels to produce a data condition number. Applications of the anomaly metric computation include the scrubbing of signal archives for epileptic seizure detection/prediction/counter-prediction algorithm training, pre-processing of multi-channel signals for real-time monitoring of bio-systems, and boot-up and/or adaptive self-checking of such systems during normal operation.07-01-2010
20100168603BRAIN STATE ANALYSIS BASED ON SELECT SEIZURE ONSET CHARACTERISTICS AND CLINICAL MANIFESTATIONS - Systems and methods for developing a brain state analysis system using subject EEG data are provided. The analysis system distinguishes clinical from subclinical electrographic seizures and optionally distinguishes among different seizure onset characteristics. An algorithm trained on only clinical electrographic seizures may predict clinical seizures more accurately with fewer perceived false positives. In addition, algorithms trained on a particular onset condition may distinguish and advise on that onset condition when used by the patient.07-01-2010
20100168602Methods and systems for presenting an inhalation experience - Methods, computer program products, and systems are described that include accepting at least one indication of use of an inhalation device configured to dispense a bioactive agent to an individual and presenting at least one artificial sensory experience to monitor at least one side effect of the bioactive agent on the individual.07-01-2010
20110160608Brain-related chronic pain disorder diagnosis and assessment method - A method for diagnosing and assessing a brain-related chronic pain disorder. The method includes assessing a subject's brain function, determining the probability that a subject is suffering from chronic pain as a result of an abnormal brain function condition by obtaining a quantitative assessment of the subject's brain function, and making a statistical comparison between the subject's quantitative brain function assessment and either a database of quantitative assessments of the brain functions of normal, healthy individuals, or a database of quantitative assessments of the brain functions of individuals known to have been suffering from chronic pain as a result of the abnormal brain function condition.06-30-2011
20130023783S&M FOR ANALYZING AND ASSESSING DEPRESSION AND OTHER MOOD DISORDERS USING ELECTOENCEPHALOGRAHIC (EEG) MEASUREMENTS - This invention is directed to systems and methods for analyzing depression, and more particularly relates to systems and methods for analyzing and assessing depression and mood disorders in an individual using electroencephalographic measurements. Embodiments of the invention are not limited to depression, but can also include other mood disorders such as bipolar disorder and other disorders with at least one genetic-related component.01-24-2013
20080255469Method for Monitoring the Depth of Anesthesia - A method for monitoring the depth of anesthesia is provided for detecting the conscious state of one being anesthetized in order to facilitate an anesthesiologist to predict exactly the dosage of an anesthetic required. At first, an original electroencephalogram (EEG) is taken from one being tested. Then, the original electroencephalogram is analyzed by approximate entropy to obtain its approximate entropy value. Next, the approximate entropy value is multiplied by 1000/17, and the corrected value is assumed as the predicted value of depth of anesthesia. The predicted value of depth of anesthesia represents degree of the conscious state or the depth of anesthesia for the one being tested. The higher the predicted depth of anesthesia value, the more conscious the one being tested is, i.e., in a shallower depth of anesthesia. On the other hand, the lower the predicted depth of anesthesia value, the less conscious the one being tested is, i.e., in a deeper depth of anesthesia.10-16-2008
20080249430System and Method for Pain Detection and Computation of a Pain Quantification Index - A method of detecting pain in a subject, comprises the steps of generating brain wave data based on brain wave activity of the subject and comparing the brain wave data to reference data to generate result data, the reference data corresponding to at least one of (i) population normative data indicative of brain wave activity of a first plurality of individuals in an absence of pain, (ii) population reference data indicative of brain wave activity of a second plurality of individuals generated in response to pain events inflicted on the second plurality of individuals, (iii) subjective population reference data indicative of brain wave activity of a third plurality of individuals reporting a sensation of pain, and (iv) population of reference data indicative of brain wave activity of a fourth population of individuals following an intervention which has changed a subjective report of pain in combination with determining a presence of pain experienced by the subject as a function of the result data.10-09-2008
20080234596Brain Wave Measuring Method, Apparatus And Computer Readable Recording Medium Implemented With Program For Executing The Method - A method for measuring a brain wave comprises extracting positive and negative peaks from an electrocardiogram (EKG) signal reflecting heartbeat information, and positive peaks from an electroencephalogram (EEG) signal reflecting heartbeat-caused noise information and brain wave information. The positive peaks of the EEG signal are classified into a first peak group and a second peak group based on the positive peaks of the EKG signal. The first peak group is affected more greatly by the heartbeat than by the brain wave, and the second peak group is affected more greatly by the brain wave than by the heartbeat. Noise of the first and second peak groups is removed from the EEG signal.09-25-2008
20080228100Eeg Seizure Analysis - Automated seizure detection from within an electroencephalogram (EEG) by instrumental means employs novel algorithms within software, using specific measurements of individual waves in trains, rather than any “bulk” process. The acquired signal is filtered, the wave shapes are individually described within a number of parallel runs using a variety of parameters, then criteria (including regularity criteria) are calculated and applied in order to create raw detection results. Finally the raw results are “integrated” for display. As a result, reported seizures closely follow the incidence and duration of seizures detected by trained clinicians. The invention is useful in intensive-care monitoring of EEGs from neonates and in EEG monitoring in general.09-18-2008
20130178757FUNCTIONAL EEG IMAGER - A system for identifying the connectivity between different brain regions to determine the functional role of brain regions in various human and animal actions.07-11-2013
20080221472METHOD AND SYSTEM FOR MEASURING AND RANKING A POSITIVE OR NEGATIVE RESPONSE TO AUDIOVISUAL OR INTERACTIVE MEDIA, PRODUCTS OR ACTIVITIES USING PHYSIOLOGICAL SIGNALS - A system and method for calculating a valence value captures an individual's positive or negative response to a media by considering alpha asymmetry of the individual's brain. This valence value can be used to compare media based on an individual or a group of individuals. Events of the media can be contrasted and compared by the valence value as well. Statistical measurements may be taken to improve media.09-11-2008
20130204152NEUROLOGICALLY BASED NON-INVASIVE BLOOD GLUCOSE CONCENTRATION SYSTEM AND METHOD - A non-invasive blood glucose concentration sensing system and method includes sensing neurophysiological brain activity of the user during visual pigment regeneration in an eye of the user, and correlating the sensed neurophysiological brain activity to the glucose concentration in the blood of the user.08-08-2013
20130204153GENERATING AN ALARM BASED ON BRAIN WAVE PATTERNS OF A USER - A method and a device are disclosed including detecting a brainwave pattern associated with a particular mental and/or physical state of a user, classifying the detected brainwave pattern to identify the particular mental/physical state of the user, and generating an alarm signal to notify the user, other authority, and/or to be used otherwise. In various embodiments, the brainwave pattern data may be recorded and used for statistical analysis, work or process scheduling, or other management decisions. In various embodiments, the brainwave pattern is detected and/or recorded using a cap or harness with embedded electrodes, a controller for controlling the electrodes, collecting data, transmitting the data to a local or central data storage device, and generating an alarm.08-08-2013
20130204154Signal Processing Device for use in Electroencephalography and a Cable System Incorporating the Device - A signal processing device for use in electroencephalography (EEG) is disclosed including: an input for receiving an electrical signal detected at a location on the head of a patient; at least one amplifier; a high-cut filter; and at least one output; wherein the signal is filtered by the high-cut filter prior to being amplified by the amplifier, the amplified signal being made available at the at least one output.08-08-2013
20130144183System and Method for Guidance of Anesthesia, Analgesia and Amnesia - Method for determining anesthesia dosage includes following steps. First Interventional Agent (“FIA”) is administered to Patient at a first rate to achieve First Predetermined Plane of Anesthesia (“FPPA”). Brain waves of Patient are analyzed to formulate First Set of Data (“FSD”) corresponding to a self-norm during administration of FIA. First transfer function corresponding to patient biochemical reactions to FIA is computed from FSD. Rate of administration of FIA to Patient is altered by a selected amount after achievement of FPPA for first time required for Patient to deviate from FPPA by predetermined degree. An altered amount of FIA required to cause the predetermined deviation is determined as difference between amount of FIA that would have been delivered to Patient during first time at the first rate and an amount delivered to Patient during the first time at the altered rate. Patient is administered the altered amount of FIA.06-06-2013
20130172774Systems and Methods for Assessing the Effectiveness of a Therapy Including a Drug Regimen Using an Implantable Medical Device - Systems and methods rely on feedback from an active medical device or devices (e.g., neurostimulator coupled to sensing and stimulation elements such as electrodes) to assess the effectiveness of a patient's drug regimen. Such reliance may include analyzing characteristics in physiological data acquired by the medical device(s), for example, in the form of responses evoked from the patient by electrical stimulation waveforms. Systems and methods further involved adjusting one or more parameters according to which a combination therapy consisting of at least a drug regimen and an electrical stimulation therapy are delivered to a patient, in an effort to optimize the therapeutic effect of the combination. The adjustments may be automatically by one or more implanted or external hosts working together or alone, and/or with the input of a physician.07-04-2013
20120253221STIMULATORY EFFECT ESTIMATION DEVICE, SLEEP DEPTH ESTIMATION DEVICE, STIMULATORY EFFECT ESTIMATION METHOD, AND VEHICLE CONTROL DEVICE - A stimulatory effect estimation device includes a stimulus generator 10-04-2012
20100010366METHOD TO EVALUATE PSYCHOLOGICAL RESPONSES TO VISUAL OBJECTS - A method of evaluating the response of a subject to visual features of a visual display, the method including the steps of: (a) presenting a visual display having particular visual features to the subject during a first period; (b) determining brain activity of the subject during the first period; (c) presenting reference display material to a subject during a second period; (d) determining reference brain activity of the subject during the second period; (e) tracking the gaze position of at least one of the eyes of the subject on the visual display during the first period; and (f) evaluating the response of the subject to particular visual features of the visual display by determining differences in brain activity determined between steps (b) and (d) when the gaze of the subject is directed at the particular features.01-14-2010
20110270117REMOTE CONTINUOUS SEIZURE MONITOR AND ALARM - An electroencephalogram (EEG) utilizing epileptiform activity detection, warning and recording system adapted for use by non-healthcare professionals or healthcare professionals. The system is simple enough for use by untrained personnel and will be self-contained, not requiring technical setup or point of use maintenance. The system includes a small number of passive or active scalp electrodes for capturing the electrical signals in the subject's brain allowing for detection of epileptiform activity. The system will recognize epileptiform activity and will either transmit signals upon detection of epileptiform activity to either a localized warning device or to a cellular or radio receiving device. The system will note epileptiform activity in a recording component and allow for review of the epileptiform data to allow non-clinical and clinical personnel to verify such activity.11-03-2011
20130096454IMAGE REPRODUCING APPARATUS AND METHOD FOR REPRODUCING REALTIME IMAGE THEREOF - Disclosed is an image reproducing device which includes an image playback unit configured to play an image; a brain signal measuring unit configured to measure a brain signal from the human perceiving the played image; a brain signal analyzing unit configured to analyze the brain signal; a feature extracting unit configured to extract a feature from the analyzed brain signal; an image selecting unit configured to select images, corresponding to the feature from among the played images; and a brain image reproducing unit configured to obtain an average of the selected images to reproduce an image perceived through the brain.04-18-2013
20130096453BRAIN-COMPUTER INTERFACE DEVICES AND METHODS FOR PRECISE CONTROL - A brain-computer interface device and method for controlling the motion of an object is provided. The brain-computer interface device includes a brain wave information processing unit, which receives converted brain wave information including object motion information, extracts object control information including the object motion information from the converted brain wave information, and transmits the extracted object control information to a hybrid control unit, and a hybrid control unit which receives target information including target location information of a target and outputs final object control information obtained by correcting the object control information including the object motion information based on the target information.04-18-2013
20130102918SYSTEM AND METHOD FOR DIAGNOSING AND TREATING PSYCHIATRIC DISORDERS - Systems and methods for diagnosing and treating psychiatric disorders are provided. For example, in one embodiment, the systems and methods generally include: (a) presenting an emotional conflict task to a patient; (b) receiving an input from the patient in response to the emotional conflict task; (c) assessing the patient's response to the emotional conflict task; and (d) modifying the emotional conflict task based on the patient's response. Such systems and methods may also be employed in a computerized training system for treating a patient with, or at risk of, a psychiatric disorder by training the patient's implicit emotional regulation.04-25-2013
20130131536System And Method For Diagnosis Of Brainstem Disorders - A system and method for detection of a brainstem disorder, such as schizophrenia, by means of brainstem audiometry is disclosed. A subject's (05-23-2013
20130131537TONG REN BRAINWAVE ENTRAINMENT - A system and method for creating a Tong Ren Brainwave Entrainment (TRBE) signal. Electroencephalography (EEG) signals are recorded from a Tong Ren practitioner during a session. Practitioner EEG signals are processed and appended to produce TRBE audio compositions for select applications according to the type of Tong Ren session.05-23-2013
20080208072Biopotential Waveform Data Fusion Analysis and Classification Method - Biopotential waveforms such as ERPs, EEGs, ECGs, or EMGs are classified accurately by dynamically fusing classification information from multiple electrodes, tests, or other data sources. These different data sources or “channels” are ranked at different time instants according to their respective univariate classification accuracies. Channel rankings are determined during training phase in which classification accuracy of each channel at each time-instant is determined. Classifiers are simple univariate classifiers which only require univariate parameter estimation. Using classification information, a rule is formulated to dynamically select different channels at different time-instants during the testing phase. Independent decisions of selected channels at different time instants are fused into a decision fusion vector. The resulting decision fusion vector is optimally classified using a discrete Bayes classifier. Finally, the dynamic decision fusion system provides high classification accuracies, is quite flexible in operation, and overcomes major limitations of classifiers applied currently in biopotential waveform studies and clinical applications.08-28-2008
20110218454Methods of Identifying Sleep & Waking Patterns and Uses - Traditional analysis of sleep patterns requires several channels of data. This analysis can be useful for customized analysis including assessing sleep quality, detecting pathological conditions, determining the effect of medication on sleep states and identifying biomarkers, and drug dosages or reactions.09-08-2011
20090054801METHOD AND DEVICE FOR DETERMINING DEPRESSIVE DISORDERS BY MEASURING BIOELECTROMAGNETIC SIGNALS OF THE BRAIN - The present invention provides a method and device for determining depressive disorders or other mental disorders related to similar brain imbalances when the combination of powers of specific frequency bands in quantitative EEG has a certain positive or negative value. The present invention performs a signal-processing task to resting EEG recording, calculates the power of two specific frequency bands, finds the combination of the powers and evaluates the result. The method can be used as quick and easy noninvasive tool for diagnosing depression related problems in different patients as separate algorithm, as a part of an EEG recording and analysis device and as a separate device.02-26-2009
20080200826Apparatus and Method of Diagnosing Health Using Cumulative Data Pattern Analysis Via Fast Fourier Transformation of Brain Wave Data Measured From Frontal Lobe - Provided is a health diagnosis apparatus and method in which brain waves are sequentially measured from the frontal lobe of a human body that is to be diagnosed when the eyes are in an eyes-open and eyes-closed state, the measured brain waves are fast Fourier transformed to then be accumulated, and then the health conditions of the respective portions of the human body can be determined according to the patterns with respective frequencies. The health condition diagnosis method includes measuring brain waves; performing a fast-Fourier-transform on the measured brain waves; classifying the frequency-based brain wave data into opened and closed eye state brain waves to thus accumulate the classified result; finding a specific frequency and a pattern thereof which repeats from the accumulated brain wave data; correspondingly connecting the frequency and the respective portions of the human body based on the specific frequency pattern; and determining the health condition of the human body. The frequency-based health condition determination is based on clinic test results.08-21-2008
20110224571NON-INVASIVE METHODS FOR EVALUATING CORTICAL PLASTICITY IMPAIRMENTS - Non-invasive and objective methods for evaluating neurological conditions that are associated with impaired cortical plasticity using, e.g., Transcranial Magnetic Stimulation (TMS) or Theta Burst Stimulation (TBS).09-15-2011
20110224569METHOD AND DEVICE FOR REMOVING EEG ARTIFACTS - Systems and methods for automatically identifying segments of EEG signals or other brain electrical activity signals that contain artifacts, and/or editing the signals to remove segments that include artifacts09-15-2011
20100286549System and Method for Assessing Efficacy of Therapeutic Agents - A method for assessing an effect of a therapeutic agent, comprises the steps of detecting brain electrical activity of a subject to generate a first set of brain wave data and extracting from the first set of brain wave data first data features sensitive to a neurological disorder in combination with the steps of comparing the first data features to control data to define a baseline profile of brain electropathophysiology and computing one of a first classifying score and a first discriminant score based on the baseline profile to estimate a probability that the baseline profile corresponds to a predetermined pathophysiological condition.11-11-2010
20110237971DISCRETE CHOICE MODELING USING NEURO-RESPONSE DATA - A system obtains neuro-response data as well as survey based data during discrete choice modeling to evaluate subject decision making processes. A discrete choice model evaluates a decision made by a subject as a function of multiple variables. Neuro-response data vectors and orthogonal survey based data vectors are weighted and combined to generate multi-dimensional vectors. The multi-dimensional vectors are used to estimate the effectiveness of changing particular variables in modifying subject behavior.09-29-2011
20120277618SEIZURE PROBABILITY METRICS - In some examples, systems, devices, and techniques for determining a particular sleep stage of a patient, determining a seizure state of the patient during the particular sleep stage, and generating a seizure probability metric for the particular sleep stage based on the sleep stage and seizure state are described. In some cases, a patient may be more susceptible to seizure events during particular sleep stages. One or more seizure probability metrics indicative of a patient's susceptibility to seizure events during a particular sleep stage may be useful in creating a patient-specific treatment regimen.11-01-2012
20100022907Methods based on fluctuations in cortical synchronization - A method of identifying a site of injury in a pediatric patient with brain injury is provided which comprises obtaining an electroencephalogram signal on the patient. The identification of phase synchrony within the signal is indicative of the site of brain injury. Electroencephalogram signals may also be used to determine prognosis of a pediatric patient in a coma in which an increase in the temporal variability of phase synchronized EEG signals over time is indicative of an improvement in the patient.01-28-2010
20130150748APPARATUS FOR COMBINING DRUG EFFECT INTERACTION BETWEEN ANAESTHETICS AND ANALGESICS AND ELECTROENCEPHALOGRAM FEATURES FOR PRECISE ASSESSMENT OF THE LEVEL OF CONSCIOUSNESS DURING ANAESTHESIA - The present invention consists of an apparatus for the on-line identification of drug effect using drug interactions and physiologic signals, in particular the interaction between anaesthetics and analgesics combined with the electroencephalogram for precise assessment of the level of consciousness in awake, sedated and anaesthetised patients. In a preferred embodiment the apparatus comprises: two infusion devices, for example syring pumps, which are connected to the patient (06-13-2013
20130131535BRAINWAVE CONTROL SYSTEM AND METHOD OPERABLE THROUGH TIME DIFFERENTIAL EVENT-RELATED POTENTIAL - A brainwave control system and method operable through time differential event-related potential includes a brainwave capturing unit attached to a user's head, a brainwave signal processing apparatus and a display unit to display at least two sets of stimuli. The brainwave signal processing apparatus includes a signal processor connected to the brainwave capturing unit and a central processor. The signal processor converts brainwave signals generated by the user after having received a set of short time interval stimuli to digital signals. The central processor performs analysis and generates identification results and executes control commands accordingly. Thus user can rapidly and accurately execute his requirements of operation control so as to achieve non-contact operation control with improved usability and practicality.05-23-2013
20100317988ACTIVATION APPARATUS, METHOD, AND COMPUTER PROGRAM FOR BRAINWAVE INTERFACE SYSTEM - A brain wave interface (IF) is started up using user's brain wave signals. A brain wave IF system comprises a brain wave measuring portion for measuring brain wave signals, a function controlling portion which analyzes an event-related potential contained in brain signals and outputs a function control signal for controlling the function of the apparatus based on the analysis results, and an output portion for outputting the function control signal. A start-up device comprises a start-up judging portion and a stimulus-attention judging portion. The start-up judging portion transmits, to the output portion, a stimulus control signal for controlling presentation/extinction of a visual stimulus which is a single item in the output portion when the brain wave IF system is not working, and compares a value of a P200 component of the event-related potential starting on a presentation timing of a visual stimulus out of the brain wave signals acquired from the brain wave measuring portion with a predetermined threshold value to determine whether or not to output a start-up trigger to the function controlling portion based on the comparison results. The stimulus-attention judging portion judges whether the user is paying attention to the visual stimulus based on an N100 component of the event-related potential starting on the presentation timing of the visual stimulus and makes the start-up judging portion start processing according to the judgment results. The brain wave IF system is started by the start-up judging portion outputting the start-up trigger.12-16-2010
20110282232NEURO-RESPONSE DATA SYNCHRONIZATION - Efficient and effective mechanisms for collecting electroencephalography (EEG) data are provided to synchronize neuro-response data collection with stimulus material presentation for in situ engagement monitoring and tracking. An EEG headset includes multiple point electrodes individually isolated and amplified. In some examples, a stimulus material presentation mechanism includes a clock source and a clock transmitter. The clock transmitter sends clock signals to a neuro-response data collection mechanism to allow synchronization of neuro-response data collected with stimulus presentation events. The EEG headset can be configured to perform processing while supporting both continuous input and output.11-17-2011
20110313309Neurophysiological Central Auditory Processing Evaluation System and Method - A system and method of central auditory processing testing and evaluation provides for identifying clinically relevant neural synchrony in the auditory brainstem pathway. The system or method finds use as a tool to evaluate auditory processing disorders, and hence, potential auditory system and/or learning disabilities. The system or method may further find use in the selection and fitting of hearing corrective appliances such as hearing aid or cochlear implant devices and/or in the selection and implementation of auditory training regimens.12-22-2011
20110313308Systems and Methods for Communicating with a Computer Using Brain Activity Patterns - The embodiments described herein are directed to systems and methods for communicating with a computer. The system includes a capture device having sensors to capture a particular brain activity pattern indicative of the mental activity generated in the user by a particular subject, a data storage device operable for storing a plurality of stored brain activity patterns each of which being associated with at least one computer readable indicia indicative of a subject that generated that brain activity pattern. The system also has a processor operable to receive the captured brain activity pattern, search for matching stored brain activity patterns, and if there is at least one matching stored brain activity pattern, retrieve the at least one indicia associated with the at least one matching stored brain activity pattern. The capture device may be an EEG capture device and the captured and stored brain activity patterns are EEG profiles.12-22-2011
20120029378AUTOMATED DETECTION OF SLEEP AND WAKING STATES - Determining low power frequency range information from spectral data. Raw signal data can be adjusted to increase dynamic range for power within low power frequency ranges as compared to higher-power frequency ranges to determine adjusted source data valuable for acquiring low power frequency range information. Low power frequency range information can be used in the analysis of a variety of raw signal data. For example, low power frequency range information within electroencephalography data for a subject from a period of sleep can be used to determine sleep states. Similarly, automated full-frequency spectral electroencephalography signal analysis can be useful for customized analysis including assessing sleep quality, detecting pathological conditions, and determining the effect of medication on sleep states.02-02-2012
20120029377Electrically Evoked Brainstem Response Measurements via Implant Prosthesis - A method of measuring electrically evoked auditory brainstem responses of a patient or animal body is provided. The method includes surgically implanting an auditory prosthesis having an electrode array, the electrode array positioned either intracochlear or substantially proximate a brainstem of the body. At least one electrode is stimulated in the electrode array. Electrically evoked auditory brainstem responses resulting from said stimulation are recorded using, at least in part, an electrode in the electrode array as a negative electrode, and a positive electrode positioned substantially proximate the vertex of the head of the body.02-02-2012
20130102919Model Based Control of Parkinson's Disease - The present invention relates to a novel means to use a fundamental model of the parts of the brain that are dysfunctional in Parkinson's disease, and related dynamical diseases of the brain, as part of a feedback control system to modulate the signs and symptoms of disease. Fundamental computational models that embody our knowledge of the anatomy, neurons, and dynamics of the parts of the brain we wish to control, and use those models to reconstruct what is inaccessible to our measurements. Through emulation the controller synchronizes to the parts of the brain we wish to observe and track. By passing simultaneous control pulses to both the model controller, as well as the brain, we control both the model and the brain. The detailed framework to embed fundamental models of the brain within a control scheme to control symptoms of Parkinsons and related dynamical diseases of the brain are disclosed.04-25-2013
20120095359 METHOD AND SYSTEM FOR DETERMINING A VARIATION IN A METABOLIC FUNCTION AND MANAGING THE VARIATION ACCORDINGLY - This invention describes a method for determining an abnormality of metabolic function and/or a variation of metabolic function, the method including the steps of, in a processing system receiving electroencephalography (EEG) signal information (04-19-2012
20130211276SENSORY-EVOKED POTENTIAL (SEP) CLASSIFICATION/DETECTION IN THE TIME DOMAIN - Techniques are disclosed for sensory-evoked potential (SEPs, e.g., visual-evoked potentials) signal detection/classification by synchronizing EEG to the repeated presentation of sensory stimuli in the time domain. In some embodiments, a system receives a plurality of EEG signal samples, generates a stimulus-locked EEG and determines whether the plurality of EEG signal samples are evoked in response to a pattern of stimulus. In some embodiments, no prior knowledge about the update pattern (such as the flashing frequency of a visual stimulus) of the stimulus and no prior knowledge about an individual user's EEG pattern are required.08-15-2013

Patent applications in class Detecting brain electric signal

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