Class / Patent application number | Description | Number of patent applications / Date published |
600533000 | Measuring respiratory flow impedance or lung elasticity | 50 |
20080221470 | RESPIRATORY SENSOR ADAPTERS FOR NASAL DEVICES - Described herein are nasal respiratory devices including an attachment site for a sensors and sensor adapters for securing at least a portion of a sensor to a nasal respiratory device. Sensor adapters typically have a body frame having at least two regions: an attachment region for securing the sensor adapter to the nasal respiratory device; and a sensor connector region for securing a sensor across from an outlet of the nasal respiratory device. | 09-11-2008 |
20080281219 | Method and System for Assessing Lung Condition and Managing Mechanical Respiratory Ventilation - The present invention discloses a novel non-invasive, bedside system and method to monitor parameters associated lung changes. A novel approach for monitoring the operation of the respiratory system of a subject is provided. There is also provided a method for objectively evaluating the benefit of one mode of ventilation over another, and for assessing the differences in regional lung vibration during different modes of mechanical ventilation. The method comprises recording one or more signals from the subject, the signal varying in time according to operation of the respiratory system; and; processing the recorded signals to obtain a predetermined functional thereof presenting one or more time-varying energy functions of the subject, an abnormality in the one or more energy functions being indicative of a suspected abnormality in the operation of the respiratory system. The signals may be acoustic signals recorded by a plurality of acoustic sensors placed over the subject's thorax or back, and the at least one time-varying energy function is obtained from one or more specific regions of lung or by summing/averaging the time-dependent acoustic signals of the plurality of sensors indicative of the whole lungs. | 11-13-2008 |
20090216145 | SYSTEM AND METHOD FOR ANALYZING AN IMPEDANCE COURSE - A system which generates a warning signal in the event of looming pulmonary edema and/or looming decompensation. The system has an impedance detection unit for determining impedance values, which represent a transthoracic impedance course, and an impedance analysis unit ( | 08-27-2009 |
20100228142 | Method and System for Determining Dynamically Respiratory Features in Spontaneoulsy Breathing Patients Receiving Mechanical Ventilatory Assist - A method for determining dynamically a respiratory feature in a spontaneously breathing patient receiving mechanical ventilatory assist comprises: modifying a level of mechanical ventilatory assist to the patient, measuring an airway pressure, detecting a change of gradient of the measured airway pressure and determining the respiratory feature based on the measured airway pressure upon detecting the change of gradient of the airway pressure. Furthermore, the method also comprises: measuring a respiratory neural drive of the patient and detecting a lowest level of the measured respiratory neural drive for determining the respiratory feature based on the detected lowest level of respiratory neural drive. | 09-09-2010 |
20110060237 | RESPIRATION IMPEDANCE MEASURING DEVICE AND METHOD, AND RESPIRATION IMPEDANCE DISPLAY METHOD - Continuous measurement of respiratory impedance with very high precision is enabled by executing noise removal. An air vibration pressure by an oscillation wave obtained by frequency culling such that the oscillation wave has only frequency components left by the culling from a plurality of different frequencies, is applied by a loudspeaker | 03-10-2011 |
20110218450 | Respiration Measurements and Dosimetry Control in Inhalation Testing Systems - Inhalation measurement systems and methods enable, during inhalant exposure, substantially real-time respiratory measurements of a test subject using techniques that obtain measurements of respiration directly from that test subject, instead of from inhalation chamber parameter measurements. Direct test subject respiratory measurements may be, by way of example only, impedance measurements. These respiratory measurements taken directly from the test subject may be transmitted, wirelessly for example, for processing during the course of the test to a processing system to determine a cumulative volume of inhalant inspired by the test subject. From that, a cumulative amount of inhalant (or dose) inspired by the test subject may be determined during the course of the inhalation compound test. In addition, a calibration procedure may be performed before the inhalant exposure to provide correlation needed to translate chest and/or abdominal wall expansion measurements, made during the test, into lung volume measurements. | 09-08-2011 |
20110218451 | NASAL DEVICES, SYSTEMS AND METHODS - Described herein are passive nasal device having a resistance to exhalation that is greater than the resistance to inhalation. Also described are devices, methods and systems for sensing and measuring intranasal pressure when a subject is wearing a passive nasal respiratory device that is configured to inhibit exhalation more than inhalation. Also described are adapters for nasal devices and methods of using a nasal device adapter. Adapters may be used so that a passive nasal device may be applied indirectly in communication with a subject's nose; in some variations this may allow the passive nasal device to be re-used. Also described herein are nasal devices having a billowing airflow resistor that is configured to have a greater resistance to exhalation than to inhalation. The billowing airflow resistor typically includes a first layer that is adjacent to a second layer; the first layer is flexible and billows opens during inhalation so that the first layer remains separated from the second layer, but remains substantially parallel to the second layer. During exhalation, the first layer collapses back down against the second layer. Additional passive nasal devices, systems and methods of using them are also described. | 09-08-2011 |
20110237970 | DETERMINING ELASTANCE AND RESISTANCE - The elastance and a resistance of a subject being ventilated are determined. The determination of elastance and resistance of the breathing of the subject is made without adjusting the ventilation of the subject to facilitate the determination. That is, the determination of elastance and resistance of the subject is made without manipulating one or more parameters of the ventilation in a manner not dictated by a treatment algorithm that is designed to ventilate the subject effectively and/or comfortably. | 09-29-2011 |
20110270114 | METHODS AND APPARATUS FOR CALIBRATING RESPIRATORY EFFORT FROM PHOTOPLETHYSMOGRAPH SIGNALS - Breathing effort of a patient, as determined (for example) from a photoplethysmograph (“PPG”) signal from the patient, can be calibrated in relation to air pressure in the patient's respiratory system. This calibration can be done by subjecting the patient to varying amounts of breathing resistance; and for each such amount, concurrently measuring (1) air pressure in the respiratory system (e.g., in the oral/nasal cavity) and (2) breathing effort (from the PPG signal). Use can be made of this calibration, e.g., during a sleep study of the patient. During such a study, breathing effort, again determined from the PPG signal and occurring, for example, during an apneic event of the patient, can be used to infer air pressure in the respiratory system by using the above calibration. | 11-03-2011 |
20110313307 | MEASURING LUNG FUNCTION AND LUNG DISEASE PROGRESSION AT A LOBAR/SEGMENTAL LEVEL - A method for determining lung function in a patient is disclosed, in which a multi-lumen catheter with an expandable occluding element at its end is used to isolate a targeted lung compartment, and respiratory characteristics at the targeted lung compartment are measured over multiple respiratory cycles. The relation between various characteristics of the respiratory cycle is used to determine compliance of lung tissue within the targeted lung compartment. | 12-22-2011 |
20120022389 | Method and Device for the Treatment of Obstructive Sleep Apnea and Snoring - The device relates to methods and devices for the treatment of obstructive sleep apnea syndrome. | 01-26-2012 |
20120101400 | RESPIRATION IMPEDANCE MEASURING DEVICE AND RESPIRATION IMPEDANCE DISPLAY METHOD - Continuous measurement of breathing impedance with extremely high precision is enabled by executing noise elimination. A loudspeaker | 04-26-2012 |
20120157872 | SYSTEM AND METHOD FOR QUANTIFYING LUNG COMPLIANCE IN A SELF-VENTILATING SUBJECT - The lung compliance of a subject that is at least partially self-ventilating is determined. The quantification of lung compliance may be an estimation, a measurement, and/or an approximate measurement. The quantification of lung compliance may be enhanced over conventional techniques and/or systems for quantifying lung compliance of self-ventilating subjects in the lung compliance may be quantified relatively accurately without an effort belt or other external sensing device that directly measures diaphragmatic muscle pressure, and without requiring the subject to manually control diaphragmatic muscle pressure. Quantification of lung compliance may be a useful tool in evaluating the health of the subject, including detection of fluid retention associated with developing acute congestive heart failure. | 06-21-2012 |
20120289852 | METHOD AND APPARATUS FOR ESTIMATING RESPIRATORY IMPEDANCE - The acoustic impedance of the respiratory system can be inferred from oscillations that are generated in an airway of a subject. The impedance describes the frequency-dependent relation between the resulting oscillations in flow and pressure. When the impedance varies from inspiration to expiration, it has to be estimated with a high time resolution. A method is provided that reliably estimates the impedance in time intervals that are short enough for physiological purposes. A simple version of the uncertainty principle has been derived for discrete time and frequency. A discrete time-frequency transform has been developed that gives an optimal time-frequency resolution according to this principle. The transform is orthonormal, which permits an analysis of variance in the discrete time-frequency domain. The impedance follows from bivariate least-squares analysis in the time-frequency domain, under the assumption that noise is present in both flow and pressure. | 11-15-2012 |
20120330177 | System and Method for Assessing Real Time Pulmonary Mechanics - A system and method of calculating an accurate estimate of pulmonary mechanics of a patient, including but not limited to compliance, resistance, and plateau pressure without modification of ventilator flow pattern. The accurate estimation of pulmonary mechanics is derived from airway pressure and flow sensors attached to the patient using novel mathematical models. These estimated figures for pulmonary mechanics (respiratory system compliance and resistance) are important for monitoring patient treatment efficacy during mechanical ventilation and ensuring alveoli do not over distend to avoid baro- and/or volutrauma, especially in patients with restrictive lung diseases. The subject method of calculating these accurate estimated figures for pulmonary mechanics is based on linear or non-linear calculations using multiple parameters derived from the above-mentioned sensors. | 12-27-2012 |
20130102916 | RESPIRATORY INTERFACE APPARATUS - A respiratory interface apparatus ( | 04-25-2013 |
20130102917 | SYSTEM AND METHOD FOR PERFORMING RESPIRATORY DIAGNOSTICS | 04-25-2013 |
20130109993 | SYSTEM AND METHOD FOR ESTIMATING UPPER AIRWAY RESISTANCE AND LUNG COMPLIANCE EMPLOYING INDUCED CENTRAL APNEAS | 05-02-2013 |
20130150747 | SYSTEM AND METHOD FOR MEASURING THE MECHANICAL IMPEDANCE OF THE RESPIRATORY SYSTEM - A system for measuring the mechanical impedance of a patient's respiratory system during spontaneous respiratory activity, characterised by comprising a fan; a motor which operates said fan; said motor and said fan being positioned within a cavity; said cavity comprising an initial end and a final end, both providing access to the outside; said cavity presenting an impedance between said initial and said final end of less than 1 cm H | 06-13-2013 |
20130165807 | SYSTEM FOR THE AUTOMATIC DETECTION OF RESPIRATORY DISEASES AND FOR THE PREDICTION OF FUTURE ACUTE AIRWAY INSTABILITIES - A system for automatically predicting acute airway events in patients, comprising: a device for measuring the respiratory impedance of a human subject during a plurality of respiratory cycles of said human subject; said respiratory impedance comprising a real part and an imaginary part; said device measuring said respiratory impedance two times per day to provide a plurality of measurements; means for calculating the relative variation of said plurality of measurements; means for evaluating the probability of respiratory pathology presence in the subject under examination when the value of the imaginary part of said impedance is greater than 35%; means for predicting a relapse in the patent under examination within an established future time window, once the presence of the pathology has been ascertained, if the variation coefficient of the real part of said impedance is greater than 0.4. | 06-27-2013 |
20130197385 | RESPIRATORY FUNCTION DETECTION - A method and system for monitoring respiratory function that includes an impedance sensor configured to sense a first thoracic impedance waveform for at least one breath of a patient, a memory configured to store a first threshold slope value, and a processor configured to determine an first breath slope value in response to the impedance waveform, compare the first breath slope value to a first threshold slope value, and determine an indication of respiratory function of the patient in response to the comparing. | 08-01-2013 |
20130197386 | RESPIRATORY FUNCTION DETECTION - A system and method for monitoring respiratory function that includes an acoustic sensing device sensing an acoustic waveform ocurring during one of an inspiration phase associated with at least one breath of a patient and an expiration phase associated with at least one breath of a patient, and a processor configured to determine changes in high frequency acoustic amplitude associated with the sensed acoustic waveform and, in response to the determined changes in high frequency acoustic amplitude, determine an indication of respiratory function. | 08-01-2013 |
20130245484 | MINIMALLY INVASIVE DETERMINATION OF COLLATERAL VENTILATION IN LUNGS - Minimally invasive methods, systems and devices are provided for qualitatively and quantitatively assessing collateral ventilation in the lungs. In particular, collateral ventilation of a target compartment within a lung of a patient is assessed by advancement of a catheter through the tracheobronchial tree to a feeding bronchus of the target compartment. The feeding bronchus is occluded by the catheter and a variety of measurements are taken with the use of the catheter in a manner which is of low risk to the patient. Examples of such measurements include but are not limited to flow rate, volume and pressure. These measurements are used to determine the presence of collateral ventilation and to quantify such collateral ventilation. | 09-19-2013 |
20130338524 | FUNCTIONAL ASSESSMENT AND TREATMENT CATHETERS AND METHODS FOR THEIR USE IN THE LUNG - Lung conditions are diagnosed and optionally treated using a functional assessment catheter or a functional lung assessment and treatment catheter. A flow restrictive component is initially placed in a bronchus or lung passageway upstream from a diseased lung region. The isolated lung region is then functionally assessed through the catheter, while the flow restrictive component remains in place. If the patient is a good candidate for treatment by occlusive or restrictive treatment techniques, the flow resistive component may be left in place. If the patient is not suitable for such treatment, the flow resistive component may be removed. | 12-19-2013 |
20140121553 | VENTILATOR-INITIATED PROMPT REGARDING AUTO-PEEP DETECTION DURING VENTILATION OF NON-TRIGGERING PATIENT - This disclosure describes systems and methods for monitoring and evaluating ventilatory parameters, analyzing those parameters and providing useful notifications and recommendations to clinicians. That is, modern ventilators monitor, evaluate, and graphically represent a myriad of ventilatory parameters. However, many clinicians may not easily identify or recognize data patterns and correlations indicative of certain patient conditions, changes in patient condition, and/or effectiveness of ventilatory treatment. Further, clinicians may not readily determine appropriate ventilatory adjustments that may address certain patient conditions and/or the effectiveness of ventilatory treatment. Specifically, clinicians may not readily detect or recognize the presence of Auto-PEEP during volume ventilation of a non-triggering patient. According to embodiments, a ventilator may be configured to monitor and evaluate diverse ventilatory parameters to detect Auto-PEEP and may issue suitable notifications and recommendations to the clinician when Auto-PEEP is implicated. The suitable notifications and recommendations may further be provided in a hierarchical format. | 05-01-2014 |
20140200476 | RESPIRATORY APPARATUS WITH IMPROVED FLOW-FLATTENING DETECTION - In a respiratory apparatus for treatment of sleep apnea and other disorders associated with an obstruction of a patient's airway and which uses an airflow signal, an obstruction index is generated which detects the flattening of the inspiratory portion of the airflow. The obstruction index is used to differentiate normal and obstructed breathing. The obstruction index is based upon different weighting factors applied to sections of the airflow signal thereby improving sensitivity to various types of respiration obstructions. | 07-17-2014 |
20140221864 | ELECTRIC IMPEDANCE TOMOGRAPHY DEVICE AND METHOD - An EIT device with a plurality of electrodes, which can be arranged about the chest of a patient, with a control and analyzing unit for feeding electrode pairs of a set of electrodes to record a voltage or current signal as a measured signal with electrode pairs acting consecutively as the feeding electrode pair to provide a matrix of image elements. A time series of the impedance change from the sequence of reconstructed matrices over at least one breath is obtained and compared to a determined time series of the mean impedance change or a time series of a measured respiration volume, by calculating for each image element a scalar value as an indicator of a deviation. The control and analyzing unit assesses and marks the corresponding image element as being non-ventilated if the indicator of the deviation meets a preset threshold value criterion. | 08-07-2014 |
20140221865 | ELECTRIC IMPEDANCE TOMOGRAPHY DEVICE AND METHOD - An electric impedance tomography device with chest electrodes, a display and a control and analyzing unit to determine a time series of a global ventilation curve from the sequence of reconstructed matrices as a time series of the mean impedance change or of a measured respiration volume, to divide an inspiration or expiration phase into a number of steps of equal volume change, to determine the times corresponding to these steps, to determine the change in local impedance between these times for each image element, the ratio of this local change in impedance to the global equal volume change to form a local sequence of relative impedance changes of the image element as a function of the steps of equal volume change, to determine a scalar indicator characteristic as a function of the steps of equal volume change and to display each image element based on the respective scalar indicator. | 08-07-2014 |
20140276173 | METHODS AND SYSTEMS FOR MONITORING RESISTANCE AND WORK OF BREATHING FOR VENTILATOR-DEPENDENT PATIENTS - Methods for non-invasively and accurately estimating and monitoring resistance and work of breathing parameters from airway pressure and flow sensors attached to the ventilator-dependent patient using an adaptive mathematical model are provided. These methods are based on calculations using multiple parameters derived from the above-mentioned sensors. The resistance and work of breathing parameters are important for: assessing patient status and diagnosis, appropriately selecting treatment, assessing efficacy of treatment, and properly adjusting ventilatory support. | 09-18-2014 |
20140296730 | System and Method for Determination of Transpulmonary Pressurein a Patient Connected to a Breathing Apparatus - A breathing apparatus ( | 10-02-2014 |
20140309546 | AIRWAY IMPEDANCE MEASUREMENT INTEGRATED WITH RESPIRATORY TREATMENT DEVICES - Airway impedance of a subject using a respiratory treatment device can be measured, in accordance with one or more embodiments. A conduit is configured to communicate a flow of inhaled gas and a flow of exhaled gas to and from an airway of the subject using the respiratory treatment device. A first valve is disposed within the conduit and configured to affect the flow of exhaled gas. One or more sensors are disposed within the conduit and are configured to provide a signal conveying information associated with one or more characteristics of gas exhaled by the subject while the flow of exhaled gas is affected or unaffected by the first valve. An airway impedance monitoring module can be executed by a processor to determine an impedance metric of the airway of the subject based on the information conveyed by the signal provided by the one or more sensors. | 10-16-2014 |
20140350429 | UPPER AIRWAY RESISTANCE MEASUREMENT DEVICE - A method of estimating the upper airway resistance of a patient using a gas delivery system includes delivering a flow of breathing gas to the patient through the patient circuit of the gas delivery system, superimposing an oscillatory pressure on the flow of breathing gas during an expiratory phase of the patient, determining a first amplitude of an oscillatory component of a gas pressure provided to the patient at an end of the expiratory phase, determining a second amplitude of an oscillatory component of a gas flow provided to the patient at the end of the expiratory phase, determining a first resistance value based on the ratio of the first amplitude to the second amplitude, and determining an upper airway resistance value based on the first resistance value. | 11-27-2014 |
20150011905 | RESPIRATORY CYCLE PATIENT VENTILATION FLOW LIMITATION DETECTION - A single respiratory cycle flow limitation detection method is disclosed. A patient gas delivery signal is received from one or more sensors in pneumatic communication with a ventilation source and a patient ventilation interface to a patient airway. The patient gas delivery signal is representative of a measure of therapeutic gas being delivered to the patient airway at a given time instant, and spans the single patient respiratory cycle. A second derivative of the patient gas delivery signal is generated and a total number of zero crossings therein are counted. These zero crossings are representative of an inflection change in the patient gas delivery signal. A flow limitation indication corresponding to the identified flow limitation is generated when there are at least two zero crossings in the second derivative of the patient gas delivery signal. An angle of deformation representing early, late, or mid-cycle obstruction onsets is generated. | 01-08-2015 |
20150045687 | DETECTION OF EXPIRATORY AIRFLOW LIMITATION IN VENTILATED PATIENT - This disclosure describes systems and methods for monitoring and evaluating data associated with ventilatory parameters to detect expiratory airflow limitation in a ventilated patient. For example, a ventilator may monitor flow and/or pressure during ventilation of the patient. Based on the flow and/or pressure measurements, or ventilatory data derived therefrom, the ventilator may calculate expiratory resistance. Moreover, the ventilator may trend expiratory resistance over time to produce an expiratory resistance waveform. In embodiments, the ventilator may calculate the slope of the expiratory resistance waveform during an initial part of exhalation. If the slope of the expiratory resistance waveform during the initial part of exhalation breaches a defined slope threshold, the ventilator may determine that the patient exhibits expiratory airflow limitation. | 02-12-2015 |
20150057559 | Pulmonary Compliance and Air Flow Resistance - Methods and apparatuses are described for direct rapid measurement of pulmonary flow resistance. A measurement of a first pressure in a gas-tight chamber is received from a pressure sensor when a gas output port of the chamber is closed, a patient is blowing into a gas inlet of the chamber at a given pressure, and a gas-flow path between the inlet and output port has a resistance value. A measurement of a second pressure in the chamber is received from the pressure sensor and a measurement of gas flow through the chamber is received from a gas flow sensor when the output port is opened and the patient is blowing into the inlet to maintain the given pressure relatively constant. A pulmonary flow resistance is computed based upon the measurement of the first pressure, the measurement of the second pressure, the resistance value, and the measurement of gas flow. | 02-26-2015 |
20150073291 | APNEA AND HYPOPNEA DETECTION - The identification of obstructed breathing, including an apnea condition and a hypopnea condition, is disclosed. A signal representative of a flow rate of therapeutic gas being delivered to the patient is received. A peak flow value and a minimum flow value over a predetermined time window encompassing a plurality of respiration cycles is derived. A polynomial difference equation from the peak flow values and the minimum flow values is generated, and a respiration index from a minimum of the polynomial difference equation is derived. The apnea and/or hypopnea condition is indicated based upon a comparison of the respiration index to a predefined obstruction threshold over a predefined obstruction time period. | 03-12-2015 |
20150099994 | METHOD AND SYSTEM FOR MONITORING THE LUNG FUNCTION OF A PATIENT - There is provided a method of monitoring the lung function of a patient, the method comprising determining one or both of an inhalation time and a rest time for a patient that is using a respiratory apparatus, the one or both of an inhalation time and a rest time for the patient being determined from measurements obtained from the respiratory apparatus, wherein the inhalation time is the amount of time for which the patient inhales through the respiratory apparatus, and the rest time is the amount of time between the end of an exhalation and the start of the next inhalation; and analyzing the determined one or both of the inhalation time and rest time to determine an indication of the lung function of the patient. | 04-09-2015 |
20150119743 | Piezoelectric Beam Bending Actuated Device for Measuring Respiratory System Impedance - An actuator ( | 04-30-2015 |
20150148699 | DETECTION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE EXACERBATIONS FROM BREATHING PATTERNS - An apparatus may include a sensing circuit and a processor. The sensing circuit is configured to generate a sensed physiological signal, wherein the physiological signal includes respiration information of a subject. The processor includes an end expiratory volume (EEV) module configured to determine a value of EEV of the subject using the sensed physiological signal, and a lung hyperinflation detection module configured to generate an indication of lung hyperinflation of the subject according to the value of EEV and provide the indication to at least one of a user or process. | 05-28-2015 |
20150320338 | DETECTION OF RESPIRATORY DISORDERS - Systems and methods for monitoring pulmonary edema and/or pulmonary congestion are based on changes in impedance parameters that are indicative of lung impedance of a patient. Early detection of changes in the status of a patient pertaining to pulmonary edema and/or pulmonary congestion may be especially beneficial for heart failure patients. Quantification is based on differentials, e.g. within a span of 24 hours, of one or more lung impedance parameters. | 11-12-2015 |
20150327806 | AIRFLOW AND AIRWAY FACTORS - A method for characterizing sleep disordered breathing may include identification of at least one of a plurality of predefined airway structural sources associated with a sleep disordered breathing event based on airflow data. In one example, an identification of at least one of a plurality of predefined airway structural sources associated with a sleep disordered breathing event is made based on data indicative of a ratio of a difference between a peak inspiratory airflow rate and a mid-inspiratory airflow rate to the peak inspiratory airflow rate captured during occurrence of the sleep disordered breathing event. | 11-19-2015 |
20160015295 | MEASURING LUNG FUNCTION AND LUNG DISEASE PROGRESSION AT A LOBAR/SEGMENTAL LEVEL - A method for determining lung function in a patient is disclosed, in which a multi-lumen catheter with an expandable occluding element at its end is used to isolate a targeted lung compartment, and respiratory characteristics at the targeted lung compartment are measured over multiple respiratory cycles. The relation between various characteristics of the respiratory cycle is used to determine compliance of lung tissue within the targeted lung compartment. | 01-21-2016 |
20160038056 | DETECTING TEMPERATURE SENSITIVITY OF A PATIENT'S AIRWAY - According to one embodiment of the present invention, an airflow perturbation device for detecting airway sensitivity to temperature comprises a pneumotachometer including a flow sensor to measure airflow through the apparatus; a perturbation mechanism to periodically alter air flow resistance in the apparatus; an air cooler; a pressure sensor to measure a difference in air pressure across the pneumotachometer and perturbation mechanism; and a computing system comprising at least one processor configured to receive data from the flow sensor and pressure sensor; and determine an airflow resistance based on the received data. Embodiments of the present invention further include a method for detecting airway sensitivity to temperature in substantially the same manners described above. | 02-11-2016 |
20160038057 | MEASURING RESPIRATORY MECHANICS PARAMETERS USING PERTURBATIONS - According to one embodiment of the present invention, a method of determining respiratory parameters comprises determining a ratio of pressure changes to flow changes induced in the breathing of a patient by an airflow perturbation device at each of a plurality of perturbation frequencies to form a dataset. Resistance, compliance, and inertance parameters of a model of a respiratory system are determined by comparing a predicted frequency dependence of the model to the dataset. Embodiments of the present invention further include a system and computer program product for determining respiratory parameters in substantially the same manners described above. | 02-11-2016 |
20160038058 | METHOD AND APPARATUS FOR ENDOBRONCHIAL DIAGNOSIS - The present invention provides systems, methods, devices and kits for assessing the level of pulmonary disease in individual lung compartments. A lung compartment comprises a subportion of a lung, such as a lobe, a segment or a subsegment, for example. By measuring individual lung compartments, the level of disease of the pulmonary system may be more precisely defined by determining values of disease parameters reflective of individual subportions or compartments of a lung. Likewise, compartments may be separately imaged to provide further measurement information. Once individual compartments are characterized, they may be compared and ranked based on a number of variables reflecting, for example, level of disease or need for treatment. Such comparison may be aided by simultaneous display of such variables or images on a visual display. Further, the same tests may be performed on the lung as a whole or on both lungs and to determine the affect of the diseased lung compartments on the overall lung performance. In addition, the diseased lung compartments may be temporarily isolated and the measurement tests performed to determine the affect of the isolation on overall lung performance. As a result, the most beneficial treatment options may be selected. | 02-11-2016 |
20160135713 | NON-INVASIVE ESTIMATION OF INTRA-PLEURAL PRESSURE AND/OR COMPUTATION OF WORK OF BREATHING BASED ON A NON-INVASIVE ESTIMATION OF INTRA-PLEURAL PRESSURE - A method includes obtaining a first physiological parameter indicative of a non-invasively measured airway pressure of a subject, obtaining a second physiological parameter indicative of a non-invasively measured air flow into the lungs of the subject, and estimating a third physiological parameter indicative of an intra-pleural pressure of the subject based on the first and second physiological parameters and generating a signal indicative thereof. An other method includes obtaining a first physiological parameter indicative of a non-invasively estimated intra-pleural pressure of a subject, determining a second physiological parameter indicative of a lung volume of the subject that is based on a third physiological parameter indicative of a non-invasively measured air flow into the lungs of the subject, and determining a work of breathing based on the first and second physiological parameters and generating a signal indicative thereof. | 05-19-2016 |
20160143535 | SYSTEMS TO MONITOR BODY PORTIONS FOR INJURY AFTER IMPACT - Systems are described for monitoring extremities for injury or damage following a physical impact. A device embodiment includes, but is not limited to, a deformable substrate integrated with a textile; a sensor assembly coupled to the deformable substrate, the sensor assembly configured to generate one or more sense signals based on detection of a physical impact to a body portion and based on detection of a physiological parameter; circuitry operably coupled to the sensor assembly and configured to receive the one or more sense signals based on detection of the physical impact and to determine whether the physical impact exceeds a threshold impact value, the circuitry configured to instruct the sensor assembly to detect one or more physiological parameters of the body portion when the physical impact exceeds the threshold impact value; and a reporting device operably coupled to the circuitry. | 05-26-2016 |
20160150998 | METHODS AND DEVICES FOR DETERMINING PULMONARY MEASUREMENT | 06-02-2016 |
20160249827 | ON-AIRWAY PULMONARY FUNCTION TESTER | 09-01-2016 |
20160249828 | ON-AIRWAY PULMONARY FUNCTION TESTER | 09-01-2016 |