Entries |
Document | Title | Date |
20080200821 | LEFT ATRIAL ACCESS APPARATUS AND METHODS - Left atrial access apparatus and methods are described herein. Different parameters, such as oxygen saturation difference, between the left and right atrial chambers is utilized to guide a needle or catheter into a desired position within the heart. Various sensing elements can be utilized to detect the physiological parameter difference, such as oxygen levels, in the left atrium. The sensor can be carried by the needle, at its tip or along its body, and can measure the physiological parameter levels contained in the blood, fluid, or tissue. | 08-21-2008 |
20080234588 | Method and Apparatus for Determining Cardiac Performance in a Patient with a Conductance Catheter - An apparatus for determining cardiac performance in the patient involving a conductance catheter ( | 09-25-2008 |
20080243007 | Pulmonary Artery Pressure Signals And Methods of Using - Embodiments of the invention are related to methods and systems for using a pulmonary artery pressure signal to detect and/or monitor physiological parameters, physiological status, and aspects of disorders and diseases, amongst other things. In an embodiment, the invention includes a method for detecting pulmonary symptoms of a disorder. In an embodiment, the invention includes a method for detecting a pathological change to a tissue, structure, or fluid volume in or around the lung. In an embodiment, the invention includes a method for detecting a disorder affecting airflow. Other aspects and embodiments are provided herein. | 10-02-2008 |
20080255463 | Method of Obtaining an Estimation of a Person's Aortic Blood Pressure - A method of obtaining an estimation of a person's aortic systolic blood pressure, which method comprises non-invasively measuring the person's brachial systolic blood pressure, non-invasively measuring the person's brachial diastolic blood pressure, obtaining the person's radial augmentation index by measuring the person's radial pulse waveform, and obtaining the estimation of the person's aortic systolic blood pressure from the following equation: aSBP=α+β·rA1x+γ·bSBP+δ·bDBP where the coefficients α, β, γ and δ are constants with approximate values of α=−24.2, β=0.28, γ=0.83, δ=0.17. | 10-16-2008 |
20080262361 | SYSTEM AND METHOD FOR CALIBRATING CARDIAC PRESSURE MEASUREMENTS DERIVED FROM SIGNALS DETECTED BY AN IMPLANTABLE MEDICAL DEVICE - Various techniques are provided for calibrating and estimating left atrial pressure (LAP) using an implantable medical device, based on impedance, admittance or conductance parameters measured within a patient. In one example, default conversion factors are exploited for converting the measured parameters to estimates of LAP. The default conversion factors are derived from populations of patients. In another example, a correlation between individual conversion factors is exploited to allow for more efficient calibration. In yet another example, differences in thoracic fluid states are exploited during calibration. In still yet another example, a multiple stage calibration procedure is described, wherein both invasive and noninvasive calibration techniques are exploited. In a still further example, a therapy control procedure is provided, which exploits day time and night time impedance/admittance measurements. | 10-23-2008 |
20080275350 | SYSTEM FOR ANCHORING AN IMPLANTABLE SENSOR IN A VESSEL - A system and a method of disposing a second sensor module overlying a first sensor module system is described. A first assembly including an expandable anchor and a sensor module is at least partially overlapped by a second assembly including an expandable anchor and a sensor module. If necessary or desired, the functions of the second sensor module can replace the functions of the first sensor module. The sensor module may include a blood pressure sensor. | 11-06-2008 |
20080281210 | Arterial pressure sensing device - An implantable medical device including a tubular housing defining a passage between a proximal end and a distal end of the housing. The passage providing fluid communication through the housing. A sensing unit is positioned within the passage and coupled to the housing. The sensing unit is configured to sense at least one of a physical, chemical, and physiological parameter within the passage. | 11-13-2008 |
20080312543 | MEASUREMENT OF PULMONARY HYPERTENSION FROM WITHIN THE AIRWAYS - This is directed to methods and devices suited for airway based measurements of pressure in a pulmonary artery. A device is advanced into an airway and in the vicinity of the pulmonary artery. Physical properties of the pulmonary artery are observed through the airway wall using one or more minimally invasive modalities. In a variation, a bronchial balloon catheter measures pressure of the pulmonary artery. | 12-18-2008 |
20090024042 | METHOD AND SYSTEM FOR MONITORING VENTRICULAR FUNCTION OF A HEART - A method for monitoring a right atrial pressure (RAP) and a left atrial pressure (LAP) for diagnosis of a heart condition includes positioning a transseptal device with respect to a pulmonary artery to monitor at least one flow characteristic of blood through the pulmonary artery. The transseptal device is configured to generate one or more signals representative of the at least one flow characteristic. A right ventricular end diastolic pressure (RVEDP) and a left ventricular end diastolic pressure (LVEDP) are detected to facilitate monitoring the heart condition. | 01-22-2009 |
20090048524 | IMPLANTABLE PRESSURE MEASURING UNIT AND CONFIGURATION FOR INTERNAL PRESSURE MEASUREMENT IN A BLOOD VESSEL - Implantable pressure measuring unit for internal pressure measurement in a blood vessel or heart of a patient, having a pressure sensor having electrical signal output, fixing means adapted to the intended measurement location for fixing the pressure sensor, a power supply unit of the pressure sensor, a signal detection unit connected by a line to the signal output of the pressure sensor, and a transmitting unit connected to a measurement data output of the signal detection unit, in particular for wireless transmission of measurement data to an analysis unit, in particular outward from the patient body. | 02-19-2009 |
20090062667 | Implantable Systemic Blood Pressure Measurement Systems and Methods - Implantable systems, and methods for use therewith, for monitoring arterial blood pressure on a chronic basis are provided herein. A first signal indicative of electrical activity of a patient's heart, and a second signal indicative of mechanical activity of the patient's heart, are obtained using implanted electrodes and an implanted sensor. By measuring the times between various features of the first signal relative to features of the second signal, values indicative of systolic pressure and diastolic pressure can be determined. In specific embodiments, such features are used to determine a peak pulse arrival time (PPAT), which is used to determine the value indicative of systolic pressure. Additionally, a peak-to-peak amplitude at the maximum peak of the second signal, and the value indicative of systolic pressure, can be used to determine the value indicative of diastolic pressure. | 03-05-2009 |
20090082678 | Pressure wire assembly - Pressure sensor wire assembly for measuring pressure inside a body of a patient, the assembly comprises a pressure sensor element for measuring pressure and to generate a pressure sensor signal in response of said pressure, and a pressure sensor wire having said pressure sensor element at its distal portion, and adapted to be inserted into the body in order to position the sensor element within the body. In addition is arranged a sensor signal adapting circuitry, being an integrated part of said assembly, wherein the pressure sensor signal is applied to the adapting circuitry that is adapted to automatically generate an output pressure signal, related to the sensor signal, in a standardized format such that the measured pressure is retrievable by an external physiology monitor. The assembly further comprises an external pressure sensor arranged at the assembly to measure the pressure outside the patient's body and to generate external pressure values in dependence thereto, the external pressure values are applied to a pressure compensation means, in the assembly, adapted to generate a compensation value reflecting the external pressure variation during a measurement procedure, wherein the output pressure signal is compensated by said compensation value prior to the output pressure signal being applied to the external physiology monitor. | 03-26-2009 |
20090088650 | INTRAVASCULAR PRESSURE DEVICES INCORPORATING SENSORS MANUFACTURED USING DEEP REACTIVE ION ETCHING - An intravascular pressure sensor assembly is disclosed herein that is produced in part using photolithography and DRIE solid-state device production processes. Using DRIE production processes facilitates a number of features that could not be readily incorporated in sensor chips fabricated using mechanical saws. In accordance with a first feature, sensor chips are created with non-rectangular outlines. The sensor chip includes a widened portion that substantially abuts an inner wall of a sensor housing, and a cantilevered portion that is relatively narrow in relation to the widened portion. The non-rectangular outline of the sensor chip is formed using photolithography in combination with DRIE processing. In accordance with another feature, the sensor chip is positioned width-wise in the housing, thereby reducing a required length for the housing. In accordance with yet another feature, the sensor chip comprises one or more cutouts for receiving signal wires for connection to signal lead lines on the sensor chip. The outline of the sensor chip and the cutouts are formed using photolithography in combination with DRIE processing. | 04-02-2009 |
20090093729 | Devices and Methods for Measurement of Vessel Elasticity and Blood Pressure - Embodiments of the invention are related to devices and methods for measuring arterial elasticity and/or blood pressure, amongst other things. In an embodiment, the invention includes an implantable medical device having a sensor element that is configured to engage a vessel of a patient. The sensor element is further configured to generate a signal in response to bending of the sensor element, where bending occurs as a result of changes in the pressure within the vessel. The implantable medical device further includes a controller in signal communication with the sensor element, where the controller is configured to store information regarding the signal generated by the sensor element. Other embodiments are also included herein. | 04-09-2009 |
20090105598 | Calibration of in vivo blood pressure sensors - A method for performing an in-vivo calibration of a blood pressure sensor that is associated with an in-vivo balloon system. The method involves monitoring a patient's blood pressure by observing the system gas pressure while at the same time monitoring the patient's blood pressure through the sensor. The blood pressure measurements obtained by monitoring the system gas pressure are used as reference, or “true,” blood pressure measurements, and an “offset” is determined between the reference blood pressure measurements and the blood pressure measurements obtained through the sensor. The offset can be stored in a memory, which may also store sensor sensitivity data. The offset and/or sensitivity data may be used to adjust future measurements obtained from the sensor, thereby generating calibrated sensor measurements. | 04-23-2009 |
20090118627 | SYSTEM AND METHOD FOR EVALUATING CARDIAC PERFORMANCE RELATIVE TO PERFORMANCE OF AN INTRATHORACIC PRESSURE MANEUVER - A system and method for evaluating cardiac performance relative to performance of an intrathoracic pressure maneuver is described. Blood pressure is indirectly sensed by directly collecting intracardiac impedance measures through an implantable medical device. Cardiac functional changes to the blood pressure are evaluated in response to performance of an intrathoracic pressure maneuver. | 05-07-2009 |
20090209869 | PRESSURE RECOVERY INDEX TO ASSESS CARDIAC FUNCTION - Determining an index for assessing cardiac function. In an embodiment, a method includes receiving ventricular pressure data during an invasive cardiac procedure, wherein the received pressure data includes a diastatic ventricular pressure value, a minimum ventricular pressure value, and a predefined fiducial marker pressure value. An index value is calculated by comparing a first pressure difference to a second pressure difference. The first pressure difference represents the difference between the received diastatic ventricular pressure value and the received minimum ventricular pressure value. The second pressure difference represents the difference between the received fiducial marker pressure value and the received minimum ventricular pressure value. The index value is provided to a health care provider to assess early diastolic cardiac function. | 08-20-2009 |
20090221923 | Cardiac Disease Treatment System - Problems To provide a cardiac disease treatment system for accurately diagnosing the functional cause of an abnormality of a cardiac disease by analyzing the hemodynamic state of a patient, automatically performing medication in accordance with the diagnosis result, and treating the cardiac disease.
| 09-03-2009 |
20090247884 | CEREBRAL PERFUSION AUGMENTATION - Methods are provided for partial aortic occlusion for cerebral perfusion augmentation in patients suffering from global or focal cerebral ischemia. The descending aorta is accessed. A device is then located downstream from the takeoff of the brachiocephalic artery. The device is operated to at least partially obstruct blood flow in the aorta during systole and diastole. A physiologic parameter can be measured. The device can then be adjusted to modify the degree of obstruction based on the measured physiologic parameter. | 10-01-2009 |
20090270740 | ENHANCED PRESSURE SENSING SYSTEM AND METHOD - An enhanced pressure sensing system and method use an external diaphragm to address issues involved with accurate and prolonged measurement of fluid pressure, such as of blood flowing in a vascular structure. Some external diaphragms include a metallized layer or other highly impermeable layer to furnish a high degree of seal at least near to hermetic grade. As temperature of the intermediary fluid changes, the external diaphragm is able to move in a direction that minimizes differential pressure across the external diaphragm over an operational temperature range thereby reducing pressure change of the intermediary fluid due to change in temperature of the intermediary fluid. Relatively smooth hydrodynamic surfaces can be used as well as a bi-layer construction. | 10-29-2009 |
20090270741 | Coronary Venous System Pressure Sensing - Disclose herein is a method of measuring pressures in a coronary sinus. In one embodiment, the method includes: introducing a distal portion of a lead or tool into the coronary sinus, wherein the distal portion includes first and second pressure sensors and at least one selectably expandable member; expanding the at least one expandable member such that the first and second sensors are isolated from each other within the coronary sinus; and taking pressure measurements with the first and second sensors when isolated from each other. | 10-29-2009 |
20090270742 | DEVICES FOR FIXING A SENSOR IN A LUMEN - Apparatus for positioning at least one sensor in a body lumen, the apparatus including a fixation element, a sensor, and a connecting element that connects the sensor to the fixation element, the connecting element extending at least partially into the lumen so that the sensor is located radially inward from a wall of the lumen. | 10-29-2009 |
20090275843 | SYSTEM AND METHOD OF DETERMINING ARTERIAL BLOOD PRESSURE AND VENTRICULAR FILL PARAMETERS FROM VENTRICULAR BLOOD PRESSURE WAVEFORM DATA - A system and method of determining hemodynamic parameters uses sensed ventricular blood pressure during a portion of ventricular pressure waveform following peak pressure. An estimated arterial diastolic pressure is based upon an amplitude of the sensed ventricular pressure corresponding to a time at which a first derivative of ventricular pressure as a function of time is at a minimum (dP/dt | 11-05-2009 |
20090299198 | ESTIMATING PULMONARY ARTERY DIASTOLIC PRESSURE - A method for estimating pulmonary artery diastolic pressure, for a single heart beat, includes establishing a time window for sampling and storing pressure data points from a right ventricular pressure transducer. The time window may be established according to predetermined parameters and/or according to one or more triggering events. An approximate time at which the pulmonary artery valve opens is determined, either via the sampled pressure data points, or via another form of more direct monitoring, during the time window, in order to estimate the pulmonary artery diastolic pressure. A plurality of sets of N pressure data points may be collected, from the sampled data, and, for each collected set, a weighted sum is calculated. Each weighted sum may be employed to evaluate a quality of the sampled data and/or to estimate the pulmonary artery diastolic pressure, if the more direct monitoring of the pulmonary artery valve is not employed. | 12-03-2009 |
20090312650 | IMPLANTABLE PRESSURE SENSOR WITH AUTOMATIC MEASUREMENT AND STORAGE CAPABILITIES - Methods for activating implantable medical devices within a patient's body are disclosed. An illustrative method includes activating an implantable medical device from a low-power state to an awake state in response to a scheduled time event, sensing one or more pressure measurements within the body, computing an average pressure measurement based on the sensed pressure measurements, storing the average pressure measurement within a memory of the implantable medical device, and then returning the device to the low-power state. A triggering event such as the detection of patient activity or motion can also be used to activate the implantable medical device between the low-power state and an active state. | 12-17-2009 |
20090326390 | Pressure and Oxygen Saturation Monitoring Devices and Systems - Pressure and oxygen saturation monitoring devices and systems are disclosed. The devices, or portions thereof, can be implanted within a subject for monitoring blood pressure and oxygen saturation. | 12-31-2009 |
20100049060 | IMPLANTABLE HEMODYNAMIC MONITOR AND METHODS FOR USE THEREWITH - Provided herein are implantable systems that include an implantable photoplethysmography (PPG) sensor, which can be used to obtain an arterial PPG waveform. In an embodiment, a metric of a terminal portion of an arterial PPG waveform is determined, and a metric of an initial portion of the arterial PPG waveform is determined, and a surrogate of mean arterial pressure is determined based on the metric of the terminal portion and the metric of the initial portion. In another embodiment, a surrogate of diastolic pressure is determined based on a metric of a terminal portion of an arterial PPG waveform. In a further embodiment, a surrogate of cardiac afterload is determined based on a metric of a terminal portion of an arterial PPG waveform. | 02-25-2010 |
20100049061 | SYSTEMS AND METHODS FOR PROVIDING AUDITORY FEEDBACK DURING CATHETER PLACEMENT - A system for providing auditory feedback may include a blood pressure monitor interface for acquiring pressure waveform data from a pressure transducer indicative of blood pressure readings over time. The system may further include an anatomic location annunciator for generating an audible signal from the pressure waveform data that conveys information about the anatomic location of the pressure transducer within the heart chamber or blood vessel. | 02-25-2010 |
20100049062 | SYSTEM AND METHOD FOR ACCURATE PLACEMENT OF A CATHETER TIP IN A PATIENT - A system for accurate placement of a catheter tip in a patient, the system including a catheter adapted for placement within a patient, the catheter having a tip at a distal end thereof and having a proximal end which is normally located outside of the patient, a pressure sensor adapted to sense pressure at the tip of the catheter and catheter tip placement location indicating circuitry operative in response to at least an output of the pressure sensor for indicating the location of the catheter tip in the patient. | 02-25-2010 |
20100056931 | CARDIAC OUTPUT ESTIMATION USING PULMONARY ARTERY PRESSURE - A system and method sense a pressure signal in a pulmonary artery and compute a stroke volume and cardiac output. A pressure signal is received from an implantable pressure sensor disposed in a pulmonary artery. The pressure signal includes a systolic period and a diastolic period for determining a heart rate (HR) and a heart cycle. An iteratively-updating model can relate pressure signal and HR to a stroke volume (SV) and a cardiac output (CO). The model extracts a mean pulse pressure (MPP) from the PAP signal and receives a patient-specific vascular resistance model parameter and a patient-specific arterial compliance model parameter. CO can be calculated using the HR, the PAP signal, and the model. The vascular resistance model parameter and the arterial compliance model parameter are iteratively updated using the output of the model. | 03-04-2010 |
20100069763 | INTRAVASCULAR PRESSURE SENSOR - Pressure-sensing apparatus includes a sensor die, which is configured for percutaneous insertion through a wall of a blood vessel of a patient so as to generate an electrical signal that is responsive to a pressure in the blood vessel. A wire has a first end connected to the sensor die and a second end connected to an electronics package, which is configured for subcutaneous implantation and is connected via the wire to receive and process the electrical signal that is generated by the sensor die in order to provide an output that is indicative of the pressure. | 03-18-2010 |
20100094143 | Access Needle Pressure Sensor Device and Method of Use - A tool and method of positioning and delivering medical devices and therapeutics within the pericardial space, as well as other body part or space. A needle is inserted into the chest through a sub-xiphoid puncture, and the pressure within the needle is monitored manometrically or otherwise sensed as the needle is advanced towards the pericardial space. By reading the pressure within the needle while it is advanced, the clinician is able to know that he or she is avoiding insertion of it into organs or spaces not intended to be the target location. In addition the retractable sharp edge allows the operator to access the space and cut tissue but do so safely by retracting the sharp edge. | 04-15-2010 |
20100094144 | SYSTEMS AND METHODS FOR DETERMINING CARDIAC OUTPUT USING PULMONARY ARTERY PRESSURE MEASUREMENTS - Systems and methods for determining cardiac output are disclosed. An illustrative method of determining cardiac output includes sensing an arterial pressure waveform using a pressure sensor located within a pulmonary artery, identifying a valve closure time associated with the pulmonary valve using the sensed arterial pressure waveform, estimating stroke volume using the systolic portion of the arterial pressure waveform and the valve closure time, and obtaining a measure of cardiac output based on the estimated stroke volume. | 04-15-2010 |
20100106028 | METHODS AND SYSTEMS FOR RECHARGING IMPLANTABLE DEVICES - Methods, systems, and apparatus for recharging medical devices implanted within the body are disclosed. An illustrative method of recharging an implanted medical device includes delivering a charging device to a location adjacent to the implanted medical device, activating a charging element coupled to the charging device and transmitting charging energy to a receiver of the implanted medical device, and charging the implanted medical device using the transmitted charging energy from the charging device. | 04-29-2010 |
20100113943 | SYSTEM AND METHOD FOR SIMULTANEOUS CENTRAL AND BRACHIAL ARTERIAL PRESSURE MONITORING - An implantable medical device system and corresponding method to monitor blood pressure by transforming a measured pressure signal to estimate a blood pressure metric or waveform corresponding to a target site. An implantable sensor generates a signal corresponding to blood pressure at a first arterial branch location and a processor receiving the signal applies a transfer function to the signal to derive a blood pressure metric or waveform at a target site. | 05-06-2010 |
20100113944 | INTERPOLATING LEFT VENTRICULAR PRESSURES - Exemplary techniques and systems for interpolating left ventricular pressures are described. One technique interpolates pressures within the left ventricle from blood pressures gathered without directly sensing blood pressure in the left ventricle. | 05-06-2010 |
20100113945 | HEMODYNAMIC MONITORS AND SYSTEMS AND METHODS FOR USING THEM - Systems and methods are provided for determining the pressure-volume relationship for one or more chambers of a heart, e.g., to guide pharmacologic or other treatment of congestive heart failure. An implantable device includes a catheter including a distal end sized for introduction into a chamber of a heart, a pressure sensor for measuring pressure within the chamber, and a sensor for measuring fluid volume within the chamber. A processor coupled to the catheter obtains pressure data from the pressure sensor and fluid volume data from the volume sensor. The processor approximates fluid volume within the chamber as a function of time and determines one or more pressure-volume loops based upon the pressure data and the fluid volume. In one embodiment, the catheter is a lead and a controller which identifies changes in determinants of cardiac output. Changes in medical therapy are guided by pressure volume loop data generated. | 05-06-2010 |
20100191129 | Calibration of in vivo blood pressure sensors - A method for performing an in-vivo calibration of a blood pressure sensor that is associated with an in-vivo balloon system. The method involves monitoring a patient's blood pressure by observing the system gas pressure while at the same time monitoring the patient's blood pressure through the sensor. The blood pressure measurements obtained by monitoring the system gas pressure are used as reference, or “true,” blood pressure measurements, and an “offset” is determined between the reference blood pressure measurements and the blood pressure measurements obtained through the sensor. The offset can be stored in a memory, which may also store sensor sensitivity data. The offset and/or sensitivity data may be used to adjust future measurements obtained from the sensor, thereby generating calibrated sensor measurements. | 07-29-2010 |
20100210955 | DEVICE FOR TREATMENT OF ANEURYSM - In a method, system and device for treating aneurysm a member is placed around the aneurysm, the aneurysm can be treated and monitored. The member can comprise a sensor placed in relation to a wall portion of the aneurysm for generating a signal corresponding to a parameter related to the aneurysm or the treatment of the aneurism. For example the size of the aneurysm such as the diameter of the aneurysm can be monitored. Hereby changes in the aneurism can be detected and information about the changes of the aneurysm can be used when determining how to treat the aneurysm. | 08-19-2010 |
20100222686 | MINIATURE WIRELESS BIOMEDICAL TELEMETRY DEVICE - Provided herein are embodiments of a miniature wireless biomedical telemetry device along with systems and methods for its use. A miniature amplifier and transmitter allow recording of physiological signals from small animals, such as rats, mice and birds, as well as humans. The device is positioned externally and is easily replaceable, as is its battery, so surgical complications and other problem problems are minimized. | 09-02-2010 |
20100262021 | Hypertension system and method - Disclosed are hypertension systems and related methods that include a blood pressure sensor located or implanted under the skin of a patient, and electronics, which may have the size and shape of a wrist watch, for example, that monitors the blood pressure of the patient by communicating with the implanted sensor. | 10-14-2010 |
20100280397 | Method and apparatus for monitoring an organ of a patient - An apparatus for determining tissue versus fluid components of an organ include a detector that generates a detector signal based on electrical signals derived from tissue and fluid. The apparatus includes a signal processor in communication with the detector which subtracts in real time a tissue component from the detector signal and produces a fluid volume signal. A method for monitoring a patient's fluid volume of a patient's organ. An apparatus for monitoring a patient's organ. A method for monitoring a patient's organ. A method to piggyback an admittance system onto a AICD/Bi-ventricular Pacemaker for a heart of a patient, in particular a weakened heart having features consistent with congestive heart failure. An apparatus for monitoring an organ, such as a heart, lungs, brain, skeletal muscle, and bladder of a patient which includes a detector which detects the admittance of the organ. The apparatus includes a transmitter in communication with the detector which transmits a wireless signal indicative of the admittance of the organ. A method for monitoring an organ of a patient includes the steps of detecting with a detector the admittance of the organ. There is the step of transmitting with a transmitter in communication with the detector a wireless signal indicative of admittance of the organ. | 11-04-2010 |
20100286536 | TRANSCEIVER UNIT IN A MEASUREMENT SYSTEM - A measurement system, comprises a sensor wire and a transceiver unit. The sensor wire comprises an insertable portion configured to be inserted in a blood vessel of a patient's body and a sensor disposed within the insertable portion at a distal end of the sensor wire. The sensor is configured to measure a variable inside the patient. The transceiver unit comprises: a housing adapted to be connected to a proximal end of the sensor wire; and a first communication module within the housing adapted to wirelessly communicate by a communication signal with an external second communication module in order to transfer information to the external second communication module. The communication signal, including sensor values, is generated by the transceiver unit and transferred as a data stream. The housing is configured to remain external to the patient's body. | 11-11-2010 |
20100286537 | SYSTEM FOR DETERMINING THE BLOOD FLOW IN A CORONARY ARTERY - The invention relates to a method and a system for determining the blood flow in an individual coronary artery of a patient, wherein the method comprises the steps of positioning a temperature sensor mounted at a distal portion of a guide wire at a distal position in the coronary artery, positioning an infusion catheter in the coronary artery such that the distal end of the infusion catheter is proximally of the temperature sensor, measuring the blood temperature with the temperature sensor, infusing cold indicator fluid with a known infusion rate and known or measurable temperature into the coronary artery by the infusion catheter, measuring the temperature of the mixture of blood and indicator fluid by the temperature sensor, and calculating the coronary blood flow by a formula based on the known and measured quantities. In an extended version, the method comprises steps for relating the calculated coronary flow value to related normal flow values, or related FFR values, or a related flow resistance. | 11-11-2010 |
20100292585 | LIVING BODY INFORMATION DETECTION APPARATUS AND BLOOD-PRESSURE METER - A living body information detection apparatus for detecting living body information at an auricle of a human body. The living body information detection apparatus having a shape that follows a cartilage of the auricle in a periphery of a concha auriculae. | 11-18-2010 |
20100298721 | APPARATUS AND METHOD FOR ESTIMATING BLOOD PRESSURE BY USING VARIABLE CHARACTERISTIC RATIO - A method of estimating blood pressure includes obtaining a pressure wave detected at a measurement body part of a subject, calculating a characteristic ratio of the subject according to a shape of the detected pressure wave based on a correlation between the characteristic ratio used to determine blood pressure at a measurement body part and the shape of the pressure wave detected at the measurement body part, and estimating blood pressure at the measurement body part of the subject is estimated using the calculated characteristic ratio. | 11-25-2010 |
20100298722 | LIVING BODY INFORMATION DETECTION APPARATUS AND BLOOD-PRESSURE METER - A living body information collecting apparatus with a part of the living body information collecting apparatus includes a shape composed of a cylinder, a cone, a prism, a pyramid, a truncated cone or a truncated pyramid. The living body information collecting apparatus further including a sensing part for collecting living body information. | 11-25-2010 |
20100305458 | BLOOD PRESSURE METER AND METHOD FOR OPERATING A BLOOD PRESSURE METER - A blood-pressure measuring device includes a resistor having a first end and a second end, a first pressure sensor disposed on the first end and a second pressure sensor disposed on the second side and configured for connection to a blood circuit, wherein the first pressure sensor, the resistor and the second pressure sensor are connected to each other in series. A computing device is connectable to the first pressure sensor and the second pressure sensor and is configured to perform a plausibility check by comparing measurement results of the first pressure sensor and of the second pressure sensor. | 12-02-2010 |
20100312126 | Calibration of in vivo blood pressure sensors - A method for performing an in-vivo calibration of a blood pressure sensor that is associated with a balloon of an in-vivo balloon system, the sensor and balloon being associated such that the sensor is in-vivo when the balloon is in-vivo. The balloon is inflated so that a gas pressure in the balloon system is indicative of a patient's blood pressure. The patient's blood pressure is monitored through two channels, the gas pressure and the sensor. The blood pressure measurements obtained by monitoring the gas pressure are used as reference, or “true,” blood pressure measurements to determine a mathematical relationship between blood pressure measurements obtained through the sensor and the reference blood pressure measurements. In this manner, future blood pressure measurements obtained through the sensor can be modified according to the mathematical relationship to generate calibrated blood pressure measurements. | 12-09-2010 |
20100317977 | IMPLANTABLE MEDICAL DEVICE WITH INTERNAL PIEZOELECTRIC ENERGY HARVESTING - Methods, systems, and apparatus for powering and/or recharging medical devices implanted within the body are described. An illustrative power generation module disposable within the interior space of an implantable medical device includes a module body that defines an interior cavity as well as a flexible diaphragm that spans the interior cavity. The flexible diaphragm includes a first electrical conductor, a piezoelectric layer disposed adjacent to the first electrical conductor, and a second electrical conductor disposed adjacent to the piezoelectric layer. The piezoelectric layer is configured to displace within the interior cavity and generate a voltage differential between the first electrical conductor and the second electrical conductor. | 12-16-2010 |
20110004109 | DETECTION OF HYPOVOLEMIA USING IMPLANTABLE MEDICAL DEVICE - An implantable medical device receives a physiological signal indicative of circulatory blood volume and detects hypovolemia from that physiological signal. In one embodiment, an implantable pulmonary artery pressure (PAP) senses a PAP signal, and the implantable medical device detects hypovolemia from the PAP signal. | 01-06-2011 |
20110028851 | Implantable Blood Pressure Monitor - A method for monitoring blood pressure includes sensing and storing sympathetic nerve activity data of a patient via a recording lead of an implantable medical device. Changes in sympathetic nerve activity from the nerve activity data are determined. Corresponding changes in blood pressure are determined from the changes in sympathetic nerve activity. An alert signal and/or modification of therapy can be provided. | 02-03-2011 |
20110028852 | Implantable Pressure Sensor with Membrane Bridge - An implantable pressure sensor having improved bend error performance is provided having a capsule housing a pressure sensing device, wherein the capsule includes an opening that allows the pressure sensing device to obtain pressure measurements from an environment surrounding the capsule. A rigid bridge is attached to the capsule so as to extend across the opening of the capsule. The bridge includes at least one opening that exposes the pressure sensing device to the surrounding environment. The rigidity of the bridge functions to prevent deformations from bending forces that are exerted on the sensor and also functions to divert loads from such bending forces away from the pressure sensing device to instead travel through the bridge, which in turn resists deformation. A fill material may be situated between the bridge and capsule so as to prevent bodily fluid or tissue from building up in the sensor under the bridge. | 02-03-2011 |
20110060229 | Systems, methods, and devices for facilitating access to target anatomical sites or environments - Methods and structures for detecting a physiologic parameter of a target anatomical environment. The device including a housing with a distal portion first port couplable to a probe and a proximal portion; and a sensing unit, a processing unit, and an output unit carried by the housing, the output unit configured to output a reporting signal based on the determined physiologic parameter value such as pressure; the sensing unit, processing unit, and output unit being disposed substantially between the first port and the proximal portion of the housing. | 03-10-2011 |
20110060230 | DETERMINATION OF DIASTOLIC HEART FAILURE - An exemplary method includes detecting a change in state of a cardiac valve, detecting elongation of the left ventricle substantially along its major axis, determining a time difference between the change in state of the cardiac valve and the elongation of the left ventricle and, based at least in part on the time difference, deciding whether a diastolic abnormality exists. Other exemplary methods, devices, systems, etc., are also disclosed. | 03-10-2011 |
20110066046 | IMPLANTABLE FLAT BLOOD PRESSURE SENSING CUFF STRUCTURE AND IMPLANTABLE BLOOD PRESSURE MONITORING DEVICE USING THE CUFF STRUCTURE - An implantable flat blood pressure sensing cuff structure and an implantable blood pressure monitoring device use a first portion of the cuff structure that comprises a sidewall that extends from a surface and contains a pressure sensor, and a second portion of the cuff structure that is configured to overlie and be removably relative to the first portion. The first and second portions of the cuff structure are configured to provide an aperture extending transversely through the cuff structure for receiving a blood vessel therein generally sandwiched between the first portion and the second portion when the second portion is positioned on the first portion such that the pressure sensor is operative to detect vessel expansion and contraction. | 03-17-2011 |
20110066047 | ECCENTRIC PRESSURE CATHETER WITH GUIDEWIRE COMPATIBILITY - There is herein described a catheter for measuring a pressure in a cardiovascular system. The catheter comprises: a guiding tube adapted for insertion into the cardiovascular system. The guiding tube defines a lumen for sliding a guidewire therethrough. The catheter further comprises a tip pressure sensor eccentrically mounted relative to the guiding tube and a signal communication means extending therefrom. The tip pressure sensor is for sensing a pressure in the cardiovascular system and the signal communicating means is for transmitting a signal indicative of the pressure to a processing device in order to obtain a pressure measurement reading. | 03-17-2011 |
20110082376 | PHYSIOLOGICAL BLOOD PRESSURE WAVEFORM COMPRESSION IN AN ACOUSTIC CHANNEL - Methods, systems and devices for processing blood pressure measurements are disclosed. An illustrative method includes transmitting a command to an implantable medical device including a blood pressure sensor. The method includes receiving a response from the implantable medical device, the response indicating that the device initiated the sensing of blood pressure measurements. The method includes receiving one or more data packets from the implantable medical device. The one or more data packets can include a base pressure measurement that is representative of a starting point of a blood pressure waveform. The one or more data packets further include a delta value measurement representative of a difference between another blood pressure measurement and the base pressure measurement, or a difference between a current measurement and one or more previous measurements. Additionally, the method includes generating a pressure waveform from the one or more data packets. | 04-07-2011 |
20110118612 | Valved Catheter with Integrated Pressure Measurement Capabilities - Valve assemblies and valved catheters including pressure sensors, and related methods for treating patients, are disclosed. The valve assembly includes a valve member extending across a first lumen and includes a planar flexible member with an internal slit acting as a valve. The valve assembly further includes a pressure sensor located distally from the valve member and in fluid communication with the first lumen. | 05-19-2011 |
20110118613 | BLOOD PRESSURE MEASUREMENT DEVICE AND BLOOD PRESSURE MEASUREMENT METHOD - A blood pressure measurement device is characterized in that the said device is designated to arithmetically apply to the computed blood pressure value a correction value that is in accordance with the difference in atmospheric pressure between the position of the blood pressure transmitting part and the position of the heart of the subject wearing the blood pressure transmitting part as obtained from the sensor signal, on the basis of the internal pressure variation of the blood pressure transmitting part. | 05-19-2011 |
20110152698 | METHOD AND APPARATUS FOR BLOOD PRESSURE WAVEFORM BASELINE ESTIMATION AND REMOVAL - An implantable medical device system including an implantable blood pressure sensor extracts a baseline signal from the sensed blood pressure signal and subtracts the extracted baseline signal from the sensed blood pressure signal to obtain a corrected pressure monitoring signal. The corrected pressure signal is monitored to detect a cardiac-related condition. | 06-23-2011 |
20110178416 | DEVICES AND METHODS FOR CONTROL OF BLOOD PRESSURE - Apparatus and methods are described including an implantable device shaped to define (a) at least two artery-contact regions, the artery-contact regions comprising struts that are configured to stretch an arterial wall by applying pressure to the arterial wall, and (b) at least two crimping regions that comprise locking mechanisms configured to prevent the crimping regions from becoming crimped due to pressure from the wall of the artery on the artery-contact regions. The crimping regions are configured to be crimped during insertion of the device, via a catheter, by the locking mechanisms being unlocked during insertion of the device. Other embodiments are also described. | 07-21-2011 |
20110178417 | METHODS FOR DETERMINING FRACTIONAL FLOW RESERVE - Devices, systems, and methods for determining fractional flow reserve. At least one method for determining fractional flow reserve of the present disclosure comprises the steps positioning a device comprising at least two sensors within a luminal organ at or near a stenosis, wherein the at least two sensors are separated a predetermined distance from one another, operating the device to determine flow velocity of a second fluid introduced into me luminal organ to temporarily displace a first fluid present within the luminal organ, and determining fractional flow reserve at or near the stenosis based upon the flow velocity, a mean aortic pressure within the luminal organ, and at least one cross-sectional area at or near the stenosis. Devices and systems useful for performing such exemplary methods are also disclosed herein. | 07-21-2011 |
20110190643 | System for Cardiac Status Determination - A system improves detection and diagnosis of blood pressure based cardiac function and tissue activities by analyzing and characterizing cardiac blood pressure signals (including non-invasive and invasive blood pressure, discrete values and continuous waveforms) using pressure signal variation and variability calculation and evaluation. The system combines blood pressure analysis with multi clinical related factors and parameters to detect and quantify cardiac health status and arrhythmia severity. The system determines an accurate time, location and severity of cardiac pathology and events by calculating blood pressure variability and statistical variation. The accurately and reliably identifies cardiac disorders, differentiates cardiac arrhythmias, characterizes pathological severity, predicts the life-threatening events, and supports evaluation of drug delivery effects. | 08-04-2011 |
20110201948 | IMPLANTABLE PRESSURE MONITOR - An implantable pressure monitor. | 08-18-2011 |
20110201949 | ANCHORED IMPLANTABLE PRESSURE MONITOR - An anchored implantable pressure monitor. | 08-18-2011 |
20110208067 | Vascular patency management using electric fields - The invention relates to the management of vascular patency by the use of implanted devices delivering one or more energies to a target vascular tissue wherein such energy delivery sources are substantially located in the vicinity of a target vascular region. The invention preferably employs electric currents as energy and utilizes one or more electrodes positioned in the vicinity of a target region and one or more electrodes located elsewhere. Such devices may be useful in the management of stenotic lesion formation adversely associated with a loss of patency in a variety of disease states or conditions, including vascular patency needed for hemodialysis used in the treatment of kidney failure. | 08-25-2011 |
20110245693 | INTRAVASCULAR PRESSURE SENSING - Devices, systems, and methods associated with pressure sensing are described herein. In one or more embodiments, an intravascular pressure sensing device includes a magnetic sensing element fixedly positioned within a sensor tube, a magnet located a distance from the magnetic sensing element within the sensor tube, the magnet movably positioned within the sensor tube via a ferrofluid magnetically attached to the magnet, and an amount of compressible fluid sealed between the magnetic sensing element and the magnet. | 10-06-2011 |
20110288422 | ESTIMATION OF PRESSURE AT REMOTE SITE BY BRACHIAL OSCILLOMETRIC WAVE FROM ANALYSIS - The present invention relates to a device and a method for estimating central systolic blood pressure based on oscillometric signals from brachial artery by the use of a pressure cuff. | 11-24-2011 |
20110301473 | SYSTEM AND METHOD FOR ASSESSING CARDIAC PERFORMANCE THROUGH CARDIAC VIBRATION MONITORING - A system and method for assessing cardiac performance through cardiac vibration monitoring is described. Cardiac vibration measures are directly collected through an implantable medical device. Cardiac events including at least one first heart sound reflected by the cardiac vibration measures are identified. The first heart sound is correlated to cardiac dimensional measures relative to performance of an intrathoracic pressure maneuver. The cardiac dimensional measures are grouped into at least one measures set corresponding to a temporal phase of the intrathoracic pressure maneuver. The at least one cardiac dimensional measures set is evaluated against a cardiac dimensional trend for the corresponding intrathoracic pressure maneuver temporal phase to represent cardiac performance. | 12-08-2011 |
20110301474 | Heart Failure Monitor Quicklook Summary for Patient Management Systems - Continuous remote monitoring of patients based on data obtained from an implantable hemodynamic monitor provides an interactive patient management system. Using network systems, patients are remotely monitored to continuously diagnose and treat heart-failure conditions. A screen displayable summary provides continuous feedback and information to physicians, patients and authorized third parties. The quick look summary includes various sites and presentation tailored to match the patients' and physicians' needs. The quick look summary further includes intelligent features that understand and retain the user's interests, preferences and use patterns. Patients, physicians and other caregivers are seamlessly connected to monitor and serve the chronic needs of heart-failure patients in a reliable and economic manner. | 12-08-2011 |
20110313302 | BLOOD PRESSURE MEASUREMENT WITH IMPLANTABLE MEDICAL DEVICE - An implantable medical device is connected to a cardiomechanic sensor implanted in or in connection with a cardiac ventricle. The sensor generates a deformation signal representative of the myocardial deformation. The implantable medical device processes the deformation signal by calculating the derivative thereof to generate a deformation rate signal representative of the rate of myocardial deformation. The deformation rate signal is filtered and respective maximum deformation rate values are identified for multiple cardiac cycles in the filtered deformation rate signal. A value representative of the systemic blood pressure is calculated based on a combination of the respective maximum deformation rate values. | 12-22-2011 |
20110319772 | LEAD MOTION SENSING VIA CABLE MICROPHONICS - An ambulatory medical device can include an excitation circuit configured to be electrically coupled to an implantable lead, the excitation circuit configured to provide a non-tissue-stimulating first signal to the implantable lead when the implantable lead is located at or near a tissue site. In an example, the system can include a detection circuit configured to be electrically coupled to the implantable lead and configured to receive a second signal, in response to the first signal, from the implantable lead, the second signal is determined at least in part by a motion of the implantable lead. | 12-29-2011 |
20110319773 | Multipurpose Host System for Invasive Cardiovascular Diagnostic Measurement Acquisition Including an Enhanced Dynamically Configured Graphical Display - The present invention provides a multipurpose host system for processing and displaying invasive cardiovascular diagnostic measurement data. The system includes a an external input signal bus interface. The bus interface receives data arising from cardiovascular diagnostic measurement sensors. Measurement processing components receive data from particular sensor types. Based on the received data, the processing components render diagnostic measurement parameter values. A multi-mode graphical user interface includes display components corresponding to data received from particular sensor types. The user interface provides recommended action prompts that guide a user through a series of actions. | 12-29-2011 |
20120046560 | APPARATUS AND METHOD FOR SENSOR DEPLOYMENT AND FIXATION - An implant assembly is implanted in vivo within a vascular system in the implant assembly has a diameter greater than a vessel and compliance characteristics such that, upon release, the implant assembly forms an interference fit is between the anchor structure and the vessel wall, thereby preventing further distal movement. | 02-23-2012 |
20120078124 | APPARATUS AND METHOD FOR SENSOR DEPLOYMENT AND FIXATION - A delivery system for fixation of an implant assembly having an intracorporeal device at a deployment site using an anchoring structure. This invention provides an implant assembly having an anchor for fixation within a vessel. The anchoring structure adapted to be delivered via a catheter. | 03-29-2012 |
20120083703 | IMPLANTABLE CORONARY PERFUSION MONITORING DEVICE - An implantable coronary perfusion monitoring device for in-vivo determination of a coronary perfusion index (CPI) indicative of the coronary perfusion of a heart has a time measurement unit to determine a blood pressure reflection wave measure t indicating the timely position in the heart cycle of the maximum of a reflected blood pressure wave and in a time period starting at a preset point of time in systole and ending at a local maximum of blood pressure following aortic valve closure and, a diastolic peak pressure measurement unit adapted to determine a diastolic peak blood pressure measure DPP related to diastolic aortic peak pressure and a systolic arterial pressure measurement unit adapted to determine a systolic arterial blood pressure measure SAP related to systolic arterial pressure, and a coronary perfusion index calculating unit adapted to determine said coronary perfusion index CPI as (t·DPP)/SAP. | 04-05-2012 |
20120108986 | Implantable Medical Sensor and Fixation System - An implantable medical device, such as a sensor for monitoring a selected internally detectable physiological parameter of a patient, is attached to a fixation member that is deployable within the patient to position and orient the sensor to enable it to perform its function. The fixation member may be configured to lie in a single plane when deployed or may be tubular in shape. The attachment of the housing and fixation member includes providing the fixation member with a linear attachment strut that is non-circular in cross section and providing the housing with external members that define an elongate channel, non-circular in cross section and receptive to the attachment strut. The attachment strut can be inserted transversely into the channel and the external member can be crimped over the strut to secure the housing and fixation member together. | 05-03-2012 |
20120108987 | IMPLANTABLE SYSTEMIC BLOOD PRESSURE MEASUREMENT SYSTEMS AND METHODS - Implantable systems, and methods for use therewith, for monitoring arterial blood pressure on a chronic basis are provided herein. A first signal indicative of electrical activity of a patient's heart, and a second signal indicative of mechanical activity of the patient's heart, are obtained using implanted electrodes and an implanted sensor. By measuring the times between various features of the first signal relative to features of the second signal, values indicative of systolic pressure and diastolic pressure can be determined. In specific embodiments, such features are used to determine a peak pulse arrival time (PPAT), which is used to determine the value indicative of systolic pressure. Additionally, a peak-to-peak amplitude at the maximum peak of the second signal, and the value indicative of systolic pressure, can be used to determine the value indicative of diastolic pressure. | 05-03-2012 |
20120157861 | DEVICES AND METHOD FOR DETERMINING AND MONITORING A CARDIAC STATUS OF A PATIENT BY USING PLVDT OR PLVST PARAMETERS - The present invention relates to an improved medical device and method for accurately and reliably determining a cardiac status of a patient. An implantable medical device, IMD, comprises a sensor arrangement adapted to sense signals related to mechanical activity of the heart and an activity level sensor arrangement adapted to sense an activity level of the patient. Further, the IMD calculates a percentage of left ventricular diastolic time (PLVDT) for a cardiac cycle corresponding to a relation between a diastolic time interval and a cardiac cycle time interval using the determined systolic and diastolic time intervals or a percentage of left ventricular systolic time (PLVST) for a cardiac cycle corresponding to a relation between a systolic interval time interval and a cardiac cycle time interval. A cardiac status is determined based on the calculated PLVDT (or PLVST) and on an activity level of the patient. | 06-21-2012 |
20120172731 | RAPID EXCHANGE GUIDE UNIT - Rapid exchange guide unit comprising an elongated support member | 07-05-2012 |
20120184859 | SYSTEMS AND METHODS FOR CORROBORATING IMPEDANCE-BASED LEFT ATRIAL PRESSURE (LAP) ESTIMATES FOR USE BY AN IMPLANTABLE MEDICAL DEVICE - Various techniques are provided for assessing the reliability of left atrial pressure (LAP) estimates made by an implantable medical device based on impedance values or related electrical values. In one example, various cardioelectric and cardiomechanical parameters are used to corroborate LAP estimation in circumstances where the LAP estimates deviate from an acceptable, satisfactory or otherwise healthy range. The cardioelectric parameters include, e.g.: ST elevation; heart rate (HR); heart rate variability (HRV); T-wave alternans (TWA); QRS waveform parameters; P-wave duration; evoked response (ER) parameters; and intrinsic PV/AV/VV conduction delays. The cardiomechanical parameters include, e.g.: heart rate turbulence (HRT); cardiogenic impedance signals; heart sounds; and non-LAP blood pressure measurements, such as aortic pressure measurements. The device compares the cardioelectric and cardiomechanical parameters against corresponding baseline values to determine whether variations in the parameters corroborate the LAP estimates. If not, the LAP estimates are selectively cancelled or suspended, or the overall procedure is re-calibrated. | 07-19-2012 |
20120190992 | SYSTEM AND METHOD FOR DETECTION OF PULMONARY EMBOLISM - Systems and methods provide for ambulatorily sensing pulmonary artery pressure from within a patient, and producing a pulmonary artery pressure measurement from the sensed pulmonary artery pressure. Power is ambulatorily provided within the patient to facilitate sensing of the pulmonary artery pressure and producing of the pulmonary artery pressure measurement. Acute pulmonary embolism is detected based on a change or rate of change in the pulmonary artery pressure measurement. An alert is preferably generated in response to detecting pulmonary embolism. | 07-26-2012 |
20120203118 | TRANSCEIVER UNIT IN A MEASUREMENT SYSTEM - A measurement system may comprise a sensor wire and a transceiver unit. The sensor wire may comprise an insertable portion configured to be inserted in a blood vessel of a patient's body and a sensor disposed within the insertable portion at a distal end of the sensor wire. The sensor is configured to measure a parameter when inserted inside the patient. The transceiver unit may comprise: a housing adapted to be connected to a proximal end of the sensor wire; and a first communication module within the housing adapted to wirelessly communicate by a communication signal with an external second communication module in order to transfer information to the external second communication module. | 08-09-2012 |
20120215117 | SYSTEMS AND METHODS FOR ESTIMATING CENTRAL ARTERIAL BLOOD PRESSURE OF A PATIENT - In specific embodiments, a method for estimating a patient's central arterial blood pressure (CBP) for use with an implantable system, comprises (a) using an implanted sensor at a first site to obtain a first signal indicative of changes in arterial blood volume at the first site, the first site being along one or more peripheral arterial structures of the patient, (b) using an implanted sensor at a second site to obtain a second signal indicative of changes in arterial blood volume at the second site, the second site being a distance from the first site downstream along an arterial path of the peripheral arterial structure of the patient, and (c) using implanted electrodes to obtain a signal indicative of electrical activity of the patient's heart. The method further comprises (d) determining a time t | 08-23-2012 |
20120220883 | PHYSIOLOGICAL SENSOR DELIVERY DEVICE AND METHOD - An intravascular sensor delivery device for measuring a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used to measure the pressure gradient across a stenotic lesion or heart valve, such as a fractional flow reserve (FFR) across a stenotic lesion. The sensor delivery device has a distal sleeve configured to pass or slide over a standard medical guidewire. The sensor delivery device can be sized to pass over different sizes of guidewires to enable usage in coronary and peripheral arteries, for example. The sensing mechanism (sensor) can be a fiber optic pressure sensor, such as a MEMS-based FabryPerot fiber optic pressure sensor, for example, or could employ some other technology, e.g., MEMS capacitive or piezoresistive sensor. | 08-30-2012 |
20120271178 | PRESSURE WIRE ASSEMBLY - A pressure sensor wire assembly measures pressure inside a body of a patient. The assembly comprises a pressure sensor element for measuring pressure and to generate a pressure sensor signal representative of the pressure, and a pressure sensor wire having the pressure sensor element at its distal portion, and adapted to be inserted into the body in order to position the sensor element within the body. A sensor signal adapting circuitry is an integrated part of the assembly, wherein the pressure sensor signal is applied to the adapting circuitry which is adapted to automatically generate an output pressure signal, related to the sensor signal, in a standardized format such that the measured pressure is retrievable by an external physiology monitor. The assembly further comprises an external pressure sensor to measure the pressure outside the patient's body and to generate external pressure values in dependence thereto. | 10-25-2012 |
20120277601 | DETECTION OF HYPOVOLEMIA USING IMPLANTABLE MEDICAL DEVICE - An implantable medical device receives a physiological signal indicative of circulatory blood volume and detects hypovolemia from that physiological signal. In one embodiment, an implantable pulmonary artery pressure (PAP) senses a PAP signal, and the implantable medical device detects hypovolemia from the PAP signal. | 11-01-2012 |
20120289840 | ESTIMATION OF PRESSURE AT REMOTE SITE BY BRACHIAL OSCILLOMETRIC WAVEFORM ANALYSIS - The present invention relates to a device and a method for estimating central systolic blood pressure based on oscillometric signals from brachial artery by the use of a pressure cuff. | 11-15-2012 |
20120296222 | Implantable Medical Sensor and Anchoring System - A medical device adapted to be implanted in a vessel of a human body includes a housing that contains means for performing medical functions and an anchor for supporting the housing in an intended location and orientation within the vessel. The anchor is expandable from a low profile configuration adapted for delivery to an expanded configuration for engagement with the vessel wall. The anchor and delivery device are adapted to enable the medical device to be retrieved and repositioned or removed from the vessel. The anchor is adapted to apply sufficient force against the vessel wall to maintain the anchor in place but less force than that required to provide scaffolding support for the vessel. | 11-22-2012 |
20130006128 | APPARATUS AND METHOD FOR PREDICTION OF RAPID SYMPTOMATIC BLOOD PRESSURE DECREASE - A monitoring device is included in a medical system to implement a method for prediction of a rapid symptomatic drop in a subject's blood pressure, e.g. during a medical treatment such as dialysis. To this aim, a pulse shape parameter (pPS) with respect to a pulse generator of the subject is registered by means of a pressure sensor arranged in an extracorporeal blood flow circuit coupled to a cardiovascular system of the subject (P). The pressure sensor is configured to detect pressure variations in blood vessels of the subject (P). It is investigated, during measurement period, whether or not one or more of the pulse shape parameters fulfil a decision criterion. An output signal (a) is generated if the decision criterion is found to be fulfilled, to indicate a predicted rapid symptomatic blood pressure decrease in the subject (P). The decision criterion may operate on pulse magnitude measures calculated for the received pulse shape parameters (pPS), or statistical dispersion measures calculated based on the thus-calculated pulse magnitude measures. | 01-03-2013 |
20130012824 | CORONARY VENOUS SYSTEM PRESSURE SENSING - Disclose herein is a method of measuring pressures in a coronary sinus. In one embodiment, the method includes: introducing a distal portion of a lead or tool into the coronary sinus, wherein the distal portion includes first and second pressure sensors and at least one selectably expandable member; expanding the at least one expandable member such that the first and second sensors are isolated from each other within the coronary sinus; and taking pressure measurements with the first and second sensors when isolated from each other. | 01-10-2013 |
20130030309 | DEVICES AND METHODS FOR TREATMENT OF HEART FAILURE AND ASSOCIATED CONDITIONS - Devices and methods of use for identification, treatment, and/or management of heart failure and/or associated conditions. Methods may include providing a baroreflex therapy system including a blood pressure sensor and a heart rate sensor, providing an implantable measurement device proximate a blood vessel of a patient, the implantable measurement device including an electrode, providing a control system coupled to the baroreflex therapy system and the implantable measurement device, the control system programmed to automatically determine an impedance of the blood vessel with the implantable measurement device over a time period of at least one cardiac cycle, determine arterial stiffness of the blood vessel based on the impedance, determine blood pressure and heart rate, and activate, deactivate or otherwise modulate the baroreflex therapy system to deliver a baroreflex therapy based on the blood pressure, heart rate and arterial stiffness. | 01-31-2013 |
20130046190 | Devices, Systems, and Methods for Assessing a Vessel - Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to assess the severity of a stenosis in the coronary arteries without the administration of a hyperemic agent. | 02-21-2013 |
20130116579 | MEDICAL SYSTEM, AND A METHOD IN RELATION TO THE MEDICAL SYSTEM - A medical system for determining the individual Fractional Flow Reserve (FFR) value for one or many lesions of interest of a blood vessel, the system comprising an intravascular pressure measurement device for acquiring pressure measurements in the blood vessel during continuous blood flow there through. The pressure measurement device comprises a pressure sensor at its distal portion. The system further comprises an FFR processor adapted to determine the FFR value related to said lesion solely/only based upon the pressure measurements performed by said pressure sensor. | 05-09-2013 |
20130116580 | SYSTEM FOR QUALITY ASSESSMENT OF PHYSIOLOGICAL SIGNALS AND METHOD THEREOF - The present disclosure relates to a system for physiological signal quality assessment, the system includes: a first filter module for implementing a filter process on an inputted first physiological signal; a first periodicity detection module for detecting periodicity of the filtered first physiological signal, and determining periodic segmentation point of the first physiological signal; a feature extracting module for extracting corresponding signal features of the first physiological signal in each heart period; and a fuzzy logic module for building up a fuzzy logic model according to the extracted signal features, and calculating a signal quality index for the first physiological signal in the relative period based on the built fuzzy logic model, and determining a signal attribute according to the signal quality index. A method for physiological signal quality assessment is provided as well. The system and method for physiological signal quality assessment calculate the signal quality index, determine the signal attribute according to the signal quality index, therefore recognize the abnormal signal out of the first physiological signal, and result in high quality physiological signals. | 05-09-2013 |
20130131523 | INTRAVASCULAR SENSING METHOD AND SYSTEM - Methods and systems for calculating a corrected Fractional Flow Reserve. Methods include delivering a pressure sensing device including a pressure sensor to a location in an artery having a stenosis, positioning the pressure sensor distal to the stenosis, measuring the distal pressure, measuring the proximal pressure, and calculating a corrected Fractional Flow Reserve using the measured proximal and distal pressures and applying a correction factor or correction equation. The correction factor or correction equation corrects for changes in the measured distal pressure caused by a presence of the pressure sensing device. A data set of correction factors or correction equations may be stored in a memory component of the system. The corrected Fractional Flow reserve may approximate the Fractional Flow Reserve that would be obtained if a different sized device was used to measure the distal pressure, such as a pressure sensing guidewire having a 0.014 inch outer diameter. | 05-23-2013 |
20130137999 | SYSTEM AND METHOD FOR ESTIMATING ELECTRICAL CONDUCTION DELAYS FROM IMMITTANCE VALUES MEASURED USING AN IMPLANTABLE MEDICAL DEVICE - Techniques are provided for estimating electrical conduction delays with the heart of a patient based on measured immittance values. In one example, impedance or admittance values are measured within the heart of a patient by a pacemaker or other implantable medical device, then used by the device to estimate cardiac electrical conduction delays. A first set of predetermined conversion factors may be used to convert the measured immittance values into conduction delay values. In some examples, the device then uses the estimated conduction delay values to estimate LAP or other cardiac pressure values. A second set of predetermined conversion factors may be used to convert the estimated conduction delays into pressure values. Techniques are also described for adaptively adjusting pacing parameters based on estimated LAP. | 05-30-2013 |
20130150737 | MICROVASCULAR OBSTRUCTION DETECTION AND THERAPY - A method of detecting and treating a microvascular obstruction is provided. In one embodiment, a catheter is provided for both detecting the microvascular obstruction and treating or removing the obstruction. | 06-13-2013 |
20130165801 | PASSIVE PRESSURE SENSOR FOR IMPLANTABLE LEAD - A passive pressure sensor is used with an implantable lead to measure pressure within a patient's heart. In some embodiments, the passive pressure sensor is incorporated into an implantable lead. In other embodiments, the passive pressure sensor is incorporated into a device that is slid onto an implantable lead. | 06-27-2013 |
20130165802 | SYSTEM AND METHOD FOR DISCRIMINATING HYPERVOLEMIA, HYPOVOLEMIA AND EUVOLEMIA USING AN IMPLANTABLE MEDICAL DEVICE - Techniques are provided for use by an implantable medical device or diagnostic sensor for detecting and discriminating euvolemia, hypervolemia and hypovolemia. In one example, the device detects a pressure signal within the patient representative of changes in cardiac pressure overall several cardiac cycles. The device generates separate time-domain and frequency-domain representations of the pressure signal and then discriminates among euvolemia, hypervolemia and hypovolemia within the patient based on an analysis of the time-domain and the frequency-domain representations of the signal. Depending upon the capabilities of the device, suitable warnings may be generated to alert the patient or caregiver. Diuretics or other medications can be titrated to address abnormal fluid conditions such as a fluid overload during hypervolemia. Techniques for detecting a pressure alternans pattern indicative of imminent decompensation are also described. | 06-27-2013 |
20130178750 | Methods and Apparatus for Regulating Blood Pressure - A blood pressure control apparatus, system, and methods of modifying intravascular blood flow of a patient is disclosed. In one aspect, the blood pressure control apparatus comprises an intravascular flow-modifying device including an expandable, hollow, stent-like support member configured for implantation within the vasculature, which includes an upstream sensor, a downstream sensor, and a flow restrictor. The flow restrictor is configured to partially occlude a vessel lumen and thereby artificially create back pressure upstream of the device, which causes dilation of the vessel wall and activation of the baroreceptors upstream of the device. Activation of the baroreceptors may depress the activity of the sympathetic nervous system, thereby contributing to a decrease in systemic blood pressure. The flow restrictor is also configured to partially occlude the renal vein lumen, thereby artificially increasing renal perfusion and depressing the baroreceptor-mediated sympathetic and neurohormonal efforts to raise blood pressure. | 07-11-2013 |
20130178751 | IMPLANTABLE MEDICAL DEVICE FOR MEASURING PRESSURE VIA AN L-C RESONANT CIRCUIT - An implantable medical device controls the excitation of and processes signals received from passive pressure sensor components of an implantable lead. The passive pressure sensor components include an inductor-capacitor (L-C) resonant circuit that has a resonant frequency that corresponds in some aspects to the pressure external to the implantable lead. The capacitive circuit portion of the resonant circuit may be flexible such that changes in pressure at the capacitive circuit cause changes in the capacitance of the capacitive circuit. Thus, changes in pressure at the pressure sensor are reflected by changes in the resonant frequency of the excited resonant circuit. The L-C resonant circuit is excited by a signal coupled to the L-C resonant circuit by the implantable medical device. In some embodiments, the implantable medical device receives such an excitation signal from an external device. In some embodiments, the implantable medical device generates the excitation signal. | 07-11-2013 |
20130190633 | Interface Devices, Systems, and Methods for Use With Intravascular Pressure Monitoring Devices - Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to provide FFR measurements in a small, compact device that integrates with existing proximal and distal pressure measurement systems and does not require a separate power source. | 07-25-2013 |
20130204147 | Atrial Fibrillation Detection Based On Pulmonary Artery Pressure Data - Atrial fibrillation (AF) is detected based on pulmonary artery pressure (PAP) data. In some embodiments, PAP data generated by a PAP sensor device implanted in or near the pulmonary artery of a patient is processed to determine whether the patient is suffering from AF. In some aspects, detection of AF is based on identifying cycle-to-cycle variations of one or more parameters derived from the PAP data. | 08-08-2013 |
20130218032 | GUIDEWIRE WITH INTERNAL PRESSURE SENSOR - The present document describes a pressure guidewire comprising: a shaft tube with a proximal section; a middle section extending from the proximal section of the shaft tube, the middle section having greater flexibility than the proximal section; an inner hypotube installed substantially within the middle section for optimal mechanical properties; a pressure sensor with a communication means routed through the middle section and the proximal section; and a sensor housing for receiving the pressure sensor. There are also described methods for joining the inner hypotube to the shaft tube. | 08-22-2013 |
20130253342 | PASS-THROUGH IMPLANTABLE MEDICAL DEVICE DELIVERY CATHETER - In one example, this disclosure is directed to a kit for intravascular implantation of an implantable medical device within a patient, the kit comprising an elongated inner sheath with a distal end, a first coupling module slidably connected to the inner sheath, an elongated outer sheath forming an inner lumen with a distal opening and a proximal opening. The outer sheath sized to traverse a vasculature of the patient. The proximal opening is configured to receive the distal end of the inner sheath. The inner lumen is sized to receive the inner sheath and to contain the implantable medical device. The kit further includes a mating coupling module that connects to the first coupling module such that the inner sheath is axially aligned with the outer sheath. The inner sheath is slidable within the outer sheath while the first coupling module is connected to the mating coupling module. | 09-26-2013 |
20130253343 | IMPLANTABLE MEDICAL DEVICE DELIVERY WITH INNER AND OUTER SHEATHS - In one example, this disclosure is directed to a kit for intravascular implantation of an implantable medical device within a patient, the kit comprising an elongated outer sheath forming a first inner lumen with a distal opening, the outer sheath sized to traverse a vasculature of the patient, and an elongated inner sheath forming a second inner lumen. An outer diameter of the inner sheath is smaller than the diameter of the first inner lumen such that the inner sheath fits within the first inner lumen, wherein the inner sheath is slidable within the first inner lumen. The second inner lumen at a distal end of the inner sheath is configured to carry an implantable medical device. The inner sheath forms a slit at a distal end of the inner sheath to facilitate deployment of the implantable medical device out of the distal opening of the outer sheath. | 09-26-2013 |
20130253344 | INTRAVASCULAR IMPLANTABLE MEDICAL DEVICE INTRODUCTION - In one example, this disclosure is directed to a kit for intravascular implantation of an implantable medical device within a patient, the kit comprising an elongated outer sheath forming an inner lumen with a distal opening, the outer sheath sized to traverse a vasculature of the patient, and an elongated inner sheath with an inflatable member at its distal portion. The inflatable member is inflatable from a proximal end of the inner sheath to close-off the distal opening of the outer sheath when inflated. The inner sheath further includes a stopper proximally located relative to the inflatable member. The inflatable member is remotely controllable from a proximal end of the inner sheath to retract in a proximal direction towards the stopper. The inflatable member can be retracted in a proximal direction towards the stopper and past an implantable medical device positioned within a distal portion of the outer sheath. | 09-26-2013 |
20130253345 | IMPLANTABLE MEDICAL DEVICE DELIVERY CATHETER WITH TETHER - In one example, this disclosure is directed to a kit for intravascular implantation of an implantable medical device within a patient, the kit comprising an elongated outer sheath forming an inner lumen with a distal opening, the outer sheath sized to traverse a vasculature of the patient, and an elongated inner sheath with an enlarged distal portion, wherein the enlarged distal portion is configured to substantially fill the inner lumen and close-off the distal opening of the outer sheath. The enlarged distal portion is slidable relative to the outer sheath. The inner sheath further includes a tether with a helical element that is remotely controllable from a proximal end of the inner sheath to release the implantable medical device from a distal portion of the outer sheath. | 09-26-2013 |
20130253346 | PASS-THROUGH IMPLANTABLE MEDICAL DEVICE DELIVERY CATHETER WITH REMOVEABLE DISTAL TIP - In one example, this disclosure is directed to a kit for intravascular implantation of an implantable medical device, the kit comprising an outer sheath, the outer sheath sized to traverse a vasculature of the patient, and an elongated inner sheath with a tapered distal end. The inner sheath is slidable within the inner lumen of the outer sheath and is selectably removable from the inner lumen of the outer sheath by sliding the inner sheath out of the proximal opening of the outer sheath. The kit includes an elongated deployment receptacle including a deployment bay slidable within the inner lumen of the outer sheath when the inner sheath is not within the inner lumen of the outer sheath. The deployment bay carries an implantable medical device through the inner lumen of the outer sheath and facilitates deployment of the implantable medical device from the distal end of the outer sheath. | 09-26-2013 |
20130253347 | TETHERED IMPLANTABLE MEDICAL DEVICE DEPLOYMENT - In one example, this disclosure is directed to a kit for intravascular implantation of an implantable medical device within a patient comprising an elongated outer sheath forming an inner lumen with a distal opening, the outer sheath sized to traverse a vasculature of the patient, and an elongated inner sheath with a stopper. The inner sheath further includes a tether configured to form a loop on a distal side of the stopper, the loop being configured to engage a looped element of the implantable medical device to couple the implantable medical device to the inner sheath. The stopper is slidable relative to the outer sheath. The tether is configured to release the looped element of the implantable medical device from the inner sheath by opening the tether loop when a portion of the stopper is located distally relative to the distal opening of the outer sheath. | 09-26-2013 |
20130261473 | DEVICES, SYSTEMS AND METHODS FOR EFFICIENT IDENTIFICATION OF IMPROVED CRT PARAMETERS - Methods, systems and devices efficiently identify cardiac resynchronization therapy (CRT) pacing parameter set(s) that provide improved hemodynamic response relative to an initial CRT pacing parameter set, wherein each CRT pacing parameter set includes at least two CRT pacing parameters. User input(s) are accepted that specify a maximum amount of time and/or parameter sets that can be used to perform testing, and specify relative importance of parameters within the sets. Based on the accepted user input(s), there is a determination of how many different variations of each of the CRT pacing parameters can be tested, and based on this determination different CRT pacing parameter sets are selected and tested to obtain a hemodynamic response measure corresponding to each of the different sets tested. Additionally, one or more of the tested CRT pacing parameter sets, if any, that provide improved hemodynamic response relative to the initial CRT pacing parameter set is/are identified. | 10-03-2013 |
20130274618 | GUIDEWIRE SYSTEM FOR USE IN TRANSCATHETER AORTIC VALVE IMPLANTATION PROCEDURES - A guidewire system may include a tubular guidewire including at least one lumen and a plurality of apertures disposed through an outer wall, and at least one pressure wire slidably disposed within the at least one lumen, the at least one pressure wire having at least one pressure sensor disposed thereon. A method of measuring a blood pressure gradient across a treatment site may include advancing the tubular guidewire to the treatment site, positioning at least one aperture distal and at least one aperture proximal of the treatment site, translating the pressure wire within the tubular guidewire, positioning the pressure wire such that a distal pressure sensor is disposed adjacent the at least one aperture distal of the treatment site, and a proximal pressure sensor is disposed adjacent the at least one aperture proximal of the treatment site, and measuring a blood pressure gradient across the treatment site. | 10-17-2013 |
20130281869 | PARTIAL AORTIC OCCLUSION DEVICES AND METHODS FOR CEREBRAL PERFUSION AUGMENTATION - Methods are provided for partial aortic obstruction for cerebral perfusion augmentation in patients suffering from global or focal cerebral ischemia. Alternatively, the methods can be used to partially obstruct aortic blood flow to condition the spinal cord to secrete neuroprotective agents prior to abdominal aortic aneurysm repair. Partial obstruction of a vessel can be accomplished by a device comprising an elongate catheter and a distally mounted expandable member. The expandable member may comprise one or two balloons. Other medical devices, such as an angioplasty, stent, or atherectomy catheter, can be inserted distal the expandable member to provide therapeutic intervention. | 10-24-2013 |
20130289420 | Device and Method for Injectate Duration Measurement and Temperature Measurement - An injection channel for a blood vessel catheter for injecting an injectate fluid into a blood vessel of a patient for carrying out thermodilution orother dilution measurements in order to determine hemodynamic parameters of the patient. The injection channel includes a pressure sensor for sensing the central venous pressure of the patient wherein. The pressure sensor also senses a threshold of pressure in the injection channel as instants of begin and end of an injection process. | 10-31-2013 |
20130324863 | GUIDE WIRE ARRANGEMENT, STRIP ARRANGEMENT AND METHODS OF FORMING THE SAME - A guide wire arrangement, a strip arrangement, a method of forming a guide wire arrangement, and a method of forming a strip arrangement are provided. The guide wire arrangement includes a strip; a sensor being disposed on a first portion of the strip; a chip being disposed next to the sensor on a second portion of the strip, wherein the second portion of the strip is next to the first portion of the strip; wherein the strip is folded at a folding point between the first portion of the strip and the second portion of the strip such that the first portion of the strip and the second portion of the strip form a stack of strip portions. | 12-05-2013 |
20130324864 | PHYSIOLOGICAL SENSOR DELIVERY DEVICE AND METHOD - An intravascular sensor delivery device for measuring a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used to measure the pressure gradient across a stenotic lesion or heart valve. For example, such a device may be used to measure fractional flow reserve (FFR) across a stenotic lesion in order to assess the severity of the lesion. The sensor delivery device has a distal sleeve configured to pass or slide over a standard medical guidewire. Some distance back from the sensor and distal sleeve, the device separates from the guidewire to permit independent control of the sensor delivery device and the guidewire. The sensor delivery device can be sized to pass over different sizes of guidewires to enable usage in coronary and peripheral arteries, for example. | 12-05-2013 |
20130331714 | PHYSIOLOGICAL SENSOR DELIVERY DEVICE AND METHOD - An intravascular sensor delivery device for measuring a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used to measure the pressure gradient across a stenotic lesion or heart valve, such as a fractional flow reserve (FFR) across a stenotic lesion. The sensor delivery device has a distal sleeve configured to pass or slide over a standard medical guidewire. The sensor delivery device can be sized to pass over different sizes of guidewires to enable usage in coronary and peripheral arteries, for example. The sensing mechanism (sensor) can be a fiber optic pressure sensor, such as a MEMS-based FabryPerot fiber optic pressure sensor, for example, or could employ some other technology, e.g., MEMS capacitive or piezoresistive sensor. | 12-12-2013 |
20130345574 | Apparatus and Method of Characterising a Narrowing in a Fluid Filled Tube - A system and method for characterising a narrowing in a fluid filled tube, the system comprising: a probe having a first measurement sensor to take an instantaneous measurement at different locations along the tube; a mechanism to draw the probe through the tube; a position measure to provide location data relating to the location at which a respective instantaneous measurement is taken by the first measurement sensor; a processor to calculate, from the instantaneous measurements, a characteristic of the tube at different locations along the tube. | 12-26-2013 |
20140005560 | Connection Structures for Intravascular Devices and Associated Systems and Methods | 01-02-2014 |
20140005561 | Connection Structures for Intravascular Devices and Associated Systems and Methods | 01-02-2014 |
20140024955 | Carotid Artery Occluding Apparatus with First and Second Occluding Balloons - An apparatus for preventing stroke by occluding blood flow through a right carotid artery and a left carotid artery of a patient is provided. The apparatus has a first occluding catheter that carries a first occluding balloon that has an inflated configuration that occludes either the right carotid artery or the left carotid artery. The apparatus also includes a second occluding catheter that carries a second occluding balloon that has an inflated configuration that occludes the other one of the right carotid artery or the left carotid artery that is not occluded by the first occluding balloon. An insertion device may also be present to allow for insertion of the first and second occluding catheters. | 01-23-2014 |
20140058276 | IMPLANTABLE PRESSURE MONITOR - An implantable pressure monitor. | 02-27-2014 |
20140066789 | SENSOR GUIDEWIRE - A sensor guidewire includes a sensor and a tubular body that covers the sensor. The tubular body includes a proximal blocking wall that is formed on a proximal side of a measurement portion of the sensor, a distal blocking wall that is formed on a distal side of the measurement portion of the sensor, and a hole that extends through the tubular body and through which blood flows into or flows out of the tubular body past the measurement portion of the sensor. The sensor is disposed on a proximal side of the hole. The proximal blocking wall and the distal blocking wall form a measurement chamber in the tubular body, and the sensor does not impede blood flow through the hole. | 03-06-2014 |
20140066790 | Pressure Sensing Intravascular Devices With Reduced Drift and Associated Systems and Methods - Intravascular devices, systems, and methods are disclosed. In some embodiments, the intravascular devices include at least one pressure sensing component positioned within a distal portion of the device. In some instances, a plurality of conductors are electrically coupled to the pressure sensing component and a potting material covers the electrical connections between the plurality of conductors and the pressure sensing component. In some instances, the potting material has a durometer hardness between about 20 Shore A and about 50 Shore A, a moisture absorption rate of about 0% per twenty-four hours, a linear shrinkage of 0%, a coefficient of thermal expansion (m/m/-° C.) of between about 1.0×10 | 03-06-2014 |
20140066791 | Mounting Structures for Components of Intravascular Devices - Intravascular devices, systems, and methods are disclosed. In some embodiments, the intravascular devices include at least one mounting structure within a distal portion of the device. In that regard, one or more electronic, optical, and/or electro-optical component is coupled to the mounting structure. In some instances, the mounting structure is formed of a plurality of material layers. In some embodiments, the material layers have substantially constant thicknesses. Methods of making and/or assembling such intravascular devices/systems are also provided. | 03-06-2014 |
20140073972 | METHODS AND SYSTEMS FOR RECHARGING AN IMPLANTED DEVICE BY DELIVERING A SECTION OF A CHARGING DEVICE ADJACENT THE IMPLANTED DEVICE WITHIN A BODY - Methods, systems, and apparatus for recharging medical devices implanted within the body are disclosed. An illustrative rechargeable system includes a charging device that includes an elongate shaft having a proximal section and a distal section. The distal section is configured to be delivered to a location within the body adjacent to the implanted medical device. The charging device includes a charging element configured to transmit charging energy to a receiver of the implanted medical device. | 03-13-2014 |
20140107505 | DETERMINATION OF VENTRICULAR PRESSURE AND RELATED VALUES - A method and a device for determining a cardiac function parameter, the device including a sonic sensor for determining timing data of a closure of a mitral valve and an aortic valve, a pressure cuff and a sensing unit coupled to the pressure cuff for sensing. The sensing unit is configured to sense, for each cardiac cycle, blood breakthrough pressure data and corresponding time data from a closing of the mitral valve and data relating to a velocity of propagation of a pressure wave as it travels along at least a portion of the pressure cuff. The device also includes a processing unit for determining a value of at least one cardiac function parameter based on the data. | 04-17-2014 |
20140114202 | BLOOD WITHDRAWAL CANNULA OF A PUMP REPLACING OR ASSISTING ACTIVITY OF THE HEART - The invention relates to a blood withdrawal cannula ( | 04-24-2014 |
20140128750 | Catheter System for Acute Neuromodulation - A neuromodulation system includes a first therapy element adapted for positioning within a superior vena cava, and a second therapy element adapted for positioning within a pulmonary artery. The first therapy element is carried on a first elongate flexible shaft, and the second therapy element is carried on a second elongate flexible shaft. One of the first and second shafts is slidably received within a lumen of the other of the first and second shafts—so that the second therapy element may be advanced within the body relative to the first therapy element. A stimulator is configured to energize the first therapy element within the first blood vessel to deliver therapy to a first nerve fiber disposed external to the superior vena cava and to energize the second therapy element within the pulmonary artery to deliver sympathetic therapy to a second nerve fiber disposed external to the pulmonary artery. For treatment of heart failure, the first nerve fiber may be a vagus nerve and the second nerve fiber may be a sympathetic nerve fiber. | 05-08-2014 |
20140135633 | Devices, Systems, and Methods for Assessing a Vessel - Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to assess the severity of a stenosis in the coronary arteries without the administration of a hyperemic agent. Further, in some implementations devices, systems, and methods of the present disclosure are configured to normalize and/or temporally align pressure measurements from two different pressure sensing instruments. Further still, in some instances devices, systems, and methods of the present disclosure are configured to exclude outlier cardiac cycles from calculations utilized to evaluate a vessel, including providing visual indication to a user that the cardiac cycles have been excluded. | 05-15-2014 |
20140142443 | SYSTEMS AND METHODS FOR EXPLOITING PULMONARY ARTERY PRESSURE OBTAINED FROM AN IMPLANTABLE SENSOR TO DETECT CARDIAC RHYTHM IRREGULARITIES - Techniques are provided for use with a pulmonary artery pressure (PAP) monitor having an implantable PAP sensor. In one example, a PAP signal is sensed that is representative of beat-by-beat variations in PAP occurring during individual cardiac cycles of the patient. The PAP monitor detects intervals within the signal corresponding to the durations of cardiac cycles, then detects cardiac rhythm irregularities based on the intervals. For example, the PAP monitor can detect and distinguish atrial fibrillation, ventricular fibrillation and ventricular tachycardia based on the stability of the intervals of the PAP signal along with other information such as ventricular rate. The PAP monitor can also detect and distinguish premature contractions based on durations of the intervals. Examples where the PAP monitor is a component of an implantable cardiac rhythm management device (CRMD) are also provided. | 05-22-2014 |
20140142444 | SYSTEMS AND METHODS FOR USING PULMONARY ARTERY PRESSURE FROM AN IMPLANTABLE SENSOR TO DETECT MITRAL REGURGITATION AND OPTIMIZE PACING DELAYS - Techniques are provided for use with a pulmonary artery pressure (PAP) monitor having an implantable PAP sensor. In one example, a PAP signal is sensed that is representative of beat-by-beat variations in PAP occurring during individual cardiac cycles of the patient. The PAP monitor detects peaks within the PAP signal corresponding to valvular regurgitation within the heart, then detects mitral regurgitation (MR) based on the peaks. In other examples, the PAP monitor optimizes pacing parameters based on the PAP signal and corresponding electrical cardiac signals. Examples are provided where the PAP monitor is an external system and other examples are provided where the PAP monitor is a component of an implantable cardiac rhythm management device. | 05-22-2014 |
20140155768 | Method and Systems for Delivering and Deploying a Sensory Implant In Situ - The present invention relates to devices, systems and methods for delivering a sensory implant along a selected linear pierced path of introduction to a wall target located on an external surface of an internal body organ; and implanting the sensory implant in the wall of the internal body organ. | 06-05-2014 |
20140155769 | Devices, Systems, and Methods for Pulmonary Arterial Hypertension (PAH) Assessment and Treatment - Provided herein are devices, systems, and methods for assessing, treating, and for developing new treatments for pulmonary arterial hypertension (PAH) using pulmonary artery pressure (PAP) values and/or cardiac output (CO) estimates. | 06-05-2014 |
20140180139 | Connectors for Use With Intravascular Devices and Associated Systems and Methods - Intravascular devices, systems, and methods are disclosed. In some embodiments, side-loading electrical connectors for use with intravascular devices are provided. The side-loading electrical connector has at least one electrical contact configured to interface with an electrical connector of the intravascular device. A first connection piece of the side-loading electrical connector is movable relative to a second connection piece between an open position and a closed position, wherein in the open position an elongated opening is formed between the first and second connection pieces to facilitate insertion of the electrical connector between the first and second connection pieces in a direction transverse to a longitudinal axis of the intravascular device and wherein in the closed position the at least one electrical contact is electrically coupled to the at least one electrical connector received between the first and second connection pieces. | 06-26-2014 |
20140180140 | Wireless Interface Devices, Systems, And Methods For Use With Intravascular Pressure Monitoring Devices - Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to collect and wirelessly distribute reliable pressure signals to other devices, and do so in a small, compact device that integrates with existing proximal and distal pressure measurement systems and does not require a separate power source. | 06-26-2014 |
20140180141 | Mounting Structures for Components of Intravascular Devices - Intravascular devices, systems, and methods are disclosed. In some embodiments, the intravascular devices include at least one mounting structure within a distal portion of the device. In that regard, one or more electronic, optical, and/or electro-optical component is coupled to the mounting structure. Methods of making and/or assembling such intravascular devices/systems are also provided. | 06-26-2014 |
20140187978 | Intravascular Devices Having Information Stored Thereon And/Or Wireless Communication Functionality, Including Associated Devices, Systems, And Methods - Intravascular devices, systems, and methods are disclosed. In some embodiments, the intravascular devices are guide-wires that include one or more sensing components and a sensor control module that stores information about the guide-wire. In some instances, the information about the guide-wire stored in the sensor control module is calibration information for a sensing component of the guide-wire. In some embodiments, the intravascular devices are guide-wires that include wireless communication functionality. In some instances, the guide-wires include one or more antennas adjacent a proximal portion of the guide-wire. In some instances, the guide-wires include passive radio frequency devices integrated into the guide-wire. Systems associated with such intravascular devices are disclosed. Methods of using such devices and systems are also disclosed. | 07-03-2014 |
20140187979 | Pressure-Sensing Guide Wire With Sliding Pressure Sensor - An intravascular sensor assembly including a flexible elongate member having a longitudinal axis (LA) is provided. The sensor assembly includes a first engagement feature proximal to a distal end of the flexible elongate member; a core member disposed inside a lumen of the flexible elongate member, the core member configured to translate within the flexible elongate member along the LA proximal to the first engagement feature; and a component holding a sensor circuit, the component fixedly secured to a distal end of the core member such that the mounting structure translates along the LA of the flexible elongate member with the core member. A system and a method for performing measurements using a sensor as above are also provided. | 07-03-2014 |
20140187980 | Hypotube Sensor Mount for Sensored Guidewire - A guidewire system for treating a patient may include a sensor assembly for detecting a physiological characteristic of a patient, the sensor assembly having a portion having a first width. The system also may include a hypotube having an integrated sensor mount formed therein for predictably locating the sensor during assembly, the hypotube having a lumen and the sensor mount being formed of opposing walls of the hypotube, the distance between the opposing walls being a second width. The first width of the sensor assembly may be greater than the second width between the opposing walls of the hypotube such that a portion of the sensor assembly lies directly on the walls of the hypotube. A sensor housing disposed about the sensor mount and configured to reinforce the hypotube at the sensor mount. | 07-03-2014 |
20140187981 | Intravascular Devices Having Information Stored Thereon And/Or Wireless Communication Functionality, Including Associated Devices, Systems, And Methods - Intravascular devices, systems, and methods are disclosed. In some embodiments, the intravascular devices are guide-wires that include one or more sensing components and a sensor control module that stores information about the guide-wire. In some instances, the information about the guide-wire stored in the sensor control module is calibration information for a sensing component of the guide-wire. In some embodiments, the intravascular devices are guide-wires that include wireless communication functionality. In some instances, the guide-wires include one or more antennas adjacent a proximal portion of the guide-wire. In some instances, the guide-wires include passive radio frequency devices integrated into the guide-wire. Systems associated with such intravascular devices are disclosed. Methods of using such devices and systems are also disclosed. | 07-03-2014 |
20140187982 | Intravascular Devices Having Information Stored Thereon And/Or Wireless Communication Functionality, Including Associated Devices, Systems, And Methods - Intravascular devices, systems, and methods are disclosed. In some embodiments, the intravascular devices are guide-wires that include one or more sensing components and a sensor control module that stores information about the guide-wire. In some instances, the information about the guide-wire stored in the sensor control module is calibration information for a sensing component of the guide-wire. In some embodiments, the intravascular devices are guide-wires that include wireless communication functionality. In some instances, the guide-wires include one or more antennas adjacent a proximal portion of the guide-wire. In some instances, the guide-wires include passive radio frequency devices integrated into the guide-wire. Systems associated with such intravascular devices are disclosed. Methods of using such devices and systems are also disclosed. | 07-03-2014 |
20140187983 | Intravascular Guidewire with Hyper Flexible Distal End Portion - In one embodiment, a sensing guidewire for performing atraumatic intravascular physiologic measurements includes an elongated core wire and a sensor disposed at a distal end portion thereof. A flexure is disposed in the core wire proximal to the sensor housing. The flexure is substantially more flexible than regions of the core wire disposed on either side of the flexure, and enables a distal end portion of the guide wire to conform to and rest against a wall of vascular structure, such as an aneurism, without exerting an undue outward pressure thereon in response to making any contact with the wall. | 07-03-2014 |
20140187984 | In-Wall Hypotube Sensor Mount for Sensored Guidewire - A guidewire system for treating a patient may include a sensor assembly for detecting a physiological characteristic of a patient and a hypotube sized for insertion into vasculature of the patient and having an integrated sensor mount formed therein for predictably locating the sensor during assembly. The hypotube may also have a wall structure and a lumen, and the sensor mount may be formed within the wall structure of the hypotube and may include a first mechanical stop configured to limit movement of the sensor assembly in at least a first dimension and a second mechanical stop configured to limit movement of the sensor assembly in at least a second dimension. A sensor housing may be disposed about the sensor mount and may have a window formed therein to provide fluid communication between the sensor assembly and an environment outside the hypotube. | 07-03-2014 |
20140187985 | Pressure Sensor Calibration Systems and Methods - Intravascular devices, systems, and methods are disclosed. In some embodiments, the intravascular devices include at least one pressure sensing component within a distal portion of the device. In that regard, one or more electrical, electronic, optical, and/or electro-optical pressure-sensing components is secured to an elongated member and the system includes components to process the output signals according to various calibration parameters. | 07-03-2014 |
20140187986 | PRESSURE-SENSING GUIDEWIRE AND SHEATH - A pressure sensing device is provided that can monitor and measure pressure at two points in a vessel or artery without moving the outer sheath or catheter of the device. The outer sheath or catheter includes two spaced apart openings that may be positioned in a vessel or artery on opposing sides of an occlusion. The device also includes an inner elongated tube with at least one opening. The inner elongated tube is slidable with respect to the outer sheath or catheter thereby permitting the opening of the elongated tube to be moved into selective registration with one of the openings of the outer sheath. A pressure measurement may be taken through one of the openings in the outer sheath by aligning the opening of the elongated tube with said opening and, then, a second pressure reading may be taken by sliding the elongated tube within the outer sheath so that the opening of the elongated tube is in registry with the other opening of the tubular sheath. As a result, pressure measurements at two points in a vessel or artery may be taken without moving the outer sheath or catheter. | 07-03-2014 |
20140207008 | Devices, Systems, and Methods for Visually Depicting a Vessel and Evaluating Treatment Options - Devices, systems, and methods for visually depicting a vessel and evaluating treatment options are disclosed. In some instances, a method of evaluating a vessel of a patient includes moving a second instrument longitudinally through a vessel of the patient from a first position to a second position while maintaining a first instrument in a fixed longitudinal position with respect to the vessel; obtaining pressure measurements from the first and second instruments while the second instrument is moved longitudinally through the vessel; visually depicting the vessel on a display based on the obtained pressure measurements; and modifying the visual depiction of the vessel to simulate one or more treatment options. Systems for performing such methods are also provided. | 07-24-2014 |
20140213915 | WIRELESS MEMS LEFT ATRIAL PRESSURE SENSOR - Systems for monitoring left atrial pressure using implantable cardiac monitoring devices and, more specifically, to a left atrial pressure sensor implanted through a septal wall are presented herein. | 07-31-2014 |
20140276136 | PERIOPERATIVE FEEDBACK IN ENDOVASCULAR ANEURYSM REPAIR USING PHYSIOLOGICAL MEASUREMENTS - The present invention generally relates to methods for detecting endoleaks associated with EVAR procedures using physiological measurements. The method can involve the taking of functional measurement data in the vicinity of a stent-graft delivered as part of the EVAR procedure and determining the presence of an endoleak based on such data. | 09-18-2014 |
20140276137 | SYSTEMS AND METHODS FOR DETERMINING CORONARY FLOW RESERVE - The invention generally relates to systems and methods for determining coronary flow reserve (CFR). The invention provides systems and methods for determining coronary flow reserve using a flow reserve index obtained at rest and during hyperemia. One flow reserve index obtained under the two conditions can be used to compute coronary flow reserve. The difference between the resting value and the hyperemic value of the index correlates to a coronary flow reserve value. | 09-18-2014 |
20140276138 | SENSING GUIDEWIRES WITH A CENTERING ELEMENT AND METHODS OF USE THEREOF - The invention generally relates to sensing guidewires with a centering element and methods of use thereof. In certain aspects, guidewires of the invention include a core member sized to fit within a vessel. A sensor is coupled to the core member. A centering element including a retracted and deployed configuration that is coupled to the core member such that upon deployment of the centering element, the sensor on the core member is located within a center of a lumen. | 09-18-2014 |
20140276139 | INTRAVASCULAR PRESSURE SENSOR CALIBRATION - The invention is a method for calibrating an intravascular pressure sensor at the point of use. By using data from a secondary pressure measurement device, e.g., an automated aortic pressure monitor, the pressure sensor can be easily calibrated over a range of temperatures and pressures relevant to the patient. Accordingly, an intravascular pressure sensor can be calibrated without undergoing a factory calibration. Additionally, in the event that the calibration is lost, the sensor can be recalibrated. | 09-18-2014 |
20140276140 | Systems and Methods for Multi-Modality Medical Data Collection - Embodiments of the present disclosure are configured to collect multi-modality medical data from a patient. In some embodiments, a method includes acquiring heartbeat data from the patient using a heart-monitoring device, the heartbeat data identifying a first cardiac cycle of the patient and selecting a diagnostic window within the first cardiac cycle of the patient, wherein the diagnostic window encompasses only a portion of the first cardiac cycle of the patient. The method also includes acquiring first medical data from the patient during the diagnostic window using a first medical device, the first medical data being associated with a first medical modality and acquiring second medical data from the patient during the diagnostic window using a second medical device, the second medical data being associated with a second medical modality different than the first medical modality. | 09-18-2014 |
20140276141 | IMPLANTABLE DEVICE WITH BRIDGE - This invention relates to an implantable device for a physiologic sensor, comprising an implantable expandable anchor, a bridge on which the sensor is secured, as well as an optional adapting ring. The invention also relates to a method of monitoring bodily functions using the anchor and sensor. The anchor is compressed and the bridge assumes an elongated shape during delivery to a target lumen. Upon deployment at the target site, the anchor expands and the bridge bows into the interior lumen of the expanded anchor, distancing the sensor from the vessel wall. This invention also relates to a method of manufacturing said device and a method of implanting a sensor. | 09-18-2014 |
20140276142 | Interface Devices, Systems, and Methods for Use with Intravascular Pressure Monitoring Devices - Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to provide FFR measurements over a length of a vessel of interest in a small, compact device that integrates with existing proximal and distal pressure measurement systems and does not require a separate power source. | 09-18-2014 |
20140276143 | Smart Interface Cable for Coupling a Diagnostic Medical Device With a Medical Measurement System - The present disclosure involves a medical device. The medical device includes an elongate cable assembly having a distal connector, a proximal connector, and a cable body coupling the proximal and distal connectors. The distal connector is configured for coupling with a diagnostic medical device. The proximal connector is configured for coupling with a medical measurement system. An electronic component is located inside the distal connector or the associated cable housing. The electronic component includes an analog-to-digital converter (ADC) and a microprocessor. The ADC is configured to receive medical data gathered by the diagnostic medical device and convert the medical data into digital signals. The microprocessor is coupled to an output of the ADC and configured to process the digital signals into a format that is readable by the medical measurement system. | 09-18-2014 |
20140288444 | SENSOR GUIDE WIRE - Sensor guide wire for intravascular measurements of physiological variables in a living body or of external signals, which sensor guide wire has a proximal region, a distal sensor region and a tip region, the sensor guide wire comprises a core wire having a longitudinal axis parallel to the longitudinal axis of the sensor guide wire, and a sensor element arranged in the distal sensor region, the sensor element has a sensitive portion for measuring the physiological variable and to generate a sensor signal in response to said variable. The sensor element has an essentially planar main surface and has its maximal extension in the plane of the main surface, and a thickness perpendicular to the plane of the main surface, wherein the sensor element is arranged in an essentially perpendicular relation to said core wire with regard to the planar main surface of the sensor element. | 09-25-2014 |
20140316289 | DEVICES, SYSTEMS, AND METHODS TO DETERMINE FRACTIONAL FLOW RESERVE - Devices, systems, and methods to determine fractional flow reserve. At least one method for determining fractional flow reserve of the present disclosure comprises the steps positioning a device comprising at least two sensors within a luminal organ at or near a stenosis, wherein the at least two sensors are separated a predetermined distance from one another, operating the device to determine flow velocity of a second fluid introduced into me luminal organ to temporarily displace a first fluid present within the luminal organ, and determining fractional flow reserve at or near the stenosis based upon the flow velocity, a mean aortic pressure within the luminal organ, and at least one cross-sectional area at or near the stenosis. Devices and systems useful for performing such exemplary methods are also disclosed herein. | 10-23-2014 |
20140330143 | METHOD AND SYSTEM FOR TREATING CARDIOVASCULAR DISEASE - A system and method for treating congestive heart failure in a patient, including: implanting at least one pressure sensor in a desired location within the patient; providing an ex-vivo interrogation system and monitoring system that can be configured to optionally affect at least one of: selectively energizing the at one pressure sensor, receiving a return or output signal from the at one pressure sensor, processing the return signal, and displaying processed data derived from the at least one pressure sensor to a physician. The system and method also includes deriving diagnostic and treatment information from the processed data and sending diagnostic and treatment information to the patient. | 11-06-2014 |
20140350417 | CARDIAC TISSUE PENETRATING DEVICES, METHODS, AND SYSTEMS FOR TREATMENT OF CONGESTIVE HEART FAILURE AND OTHER CONDITIONS - According to one embodiment, a tissue penetrating device includes an elongate shaft having a proximal end, a distal end, and a lumen extending there between. A first needle is disposed within the lumen of the elongate shaft and is extendable therefrom between a first configuration and a second configuration. In the first configuration, the first needle is disposed within the elongate shaft's lumen and is substantially aligned with an axis of the lumen. In the second configuration, the first needle extends distally of the elongate shaft's distal end and bends away from the lumen's axis. A second needle is disposed within a lumen of the first needle and is extendable therefrom when the first needle is positioned in the first configuration and when the first needle is positioned in the second configuration. The second needle may be extended from the first needle to penetrate tissue of a patient. | 11-27-2014 |
20150025397 | SYSTEM AND METHOD FOR ESTIMATING CARDIAC PRESSURE BASED ON CARDIAC ELECTRICAL CONDUCTION DELAYS USING AN IMPLANTABLE MEDICAL DEVICE - Techniques are provided for estimating left atrial pressure (LAP) or other cardiac performance parameters based on measured conduction delays. In particular, LAP is estimated based interventricular conduction delays. Predetermined conversion factors stored within the device are used to convert the various the conduction delays into LAP values or other appropriate cardiac performance parameters. The conversion factors may be, for example, slope and baseline values derived during an initial calibration procedure performed by an external system, such as an external programmer. In some examples, the slope and baseline values may be periodically re-calibrated by the implantable device itself. Techniques are also described for adaptively adjusting pacing parameters based on estimated LAP or other cardiac performance parameters. Still further, techniques are described for estimating conduction delays based on impedance or admittance values and for tracking heart failure therefrom. | 01-22-2015 |
20150025398 | Devices, Systems, and Methods for Assessing a Vessel with Automated Drift Correction - Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to assess the severity of a stenosis in the coronary arteries without the administration of a hyperemic agent. In some embodiments, the devices, systems, and methods of the present disclosure are configured to assess a vessel by automatically correcting for drift in the equipment utilized to obtain measurements related to the vessel. | 01-22-2015 |
20150032011 | FFR SENSOR HEAD DESIGN THAT MINIMIZES STRESS INDUCED PRESSURE OFFSETS - A pressure sensing medical device may include a guidewire including a tubular member having a lumen, the tubular member being translatable between a generally straightened position and a deflected position, and a pressure sensor attached at a distal end of a fiber optic extending within the lumen, the pressure sensor being disposed within a distal portion of the tubular member. The pressure sensor may include a pressure-sensitive membrane disposed on a distal end thereof. The pressure sensor may include one or more contact members capable of providing a contact point between the contact member and an inner surface of the tubular member when in the deflected position, the contact point being axially spaced apart from the membrane along a longitudinal axis of the pressure sensor. | 01-29-2015 |
20150032012 | Non-invasive Blood Pressure Measurement System and Methods of Use - Disclosed is a system that includes a signal acquisition circuit to acquire a cuff pressure signal using an inflatable cuff, and to generate an oscillometric signal from the cuff pressure signal. The system also includes a user interface to enter one or more patient-specific detection threshold values, a memory to store the cuff pressure signal, the oscillometric signal, and the one or more patient-specific detection threshold values. The system also includes a microprocessor operatively coupled to the signal acquisition circuit, the user interface, and the memory. The microprocessor includes at least one algorithm to use the cuff pressure signal, the oscillometric signal, and the entered one or more patient-specific detection threshold values to calculate patient-specific readings of at least one of mean arterial pressure, systolic blood pressure and diastolic blood pressure. Related apparatus, systems, methods and/or articles are described. | 01-29-2015 |
20150112210 | LUMEN BASED PRESSURE MEASUREMENT GUIDE WIRE SYSTEM FOR MEASURING PRESSURE IN A BODY LUMEN - A medical system utilizes a guide wire with a fluid filled internal lumen and a pressure measurement system to measure blood pressure in a body vessel. The guide wire includes an internal lumen with a distal opening for admitting fluid flow. The internal lumen is filled with a fluid or other media which can transmit pressure along the guide wire. The pressure measurement system includes a pressure transducer in fluid communication with the internal lumen of the guide wire. Pressure waveform in the body vessel are transmitted through the fluid or media from the distal opening of the internal lumen to the pressure transducer. The pressure transducer is in communication with a processor (with display) for determining the pressure acting on the pressure transducer. A pump with a fluid reservoir in fluid communication with the internal lumen of the guide wire is controlled by the processor. The pump introduces additional fluid into the guide wire lumen. | 04-23-2015 |
20150112211 | TRANSDUCER INTERFACE SYSTEM AND METHOD - A transducer interface system/method allowing conversion from an analog sensor input to a standardized analog output interface is disclosed. In some preferred embodiments the system/method permits a fiber optic pressure sensor to be interfaced to a standard patient care monitor (PCM) system using standardized Wheatstone Bridge analog interface inputs. Within this context the Wheatstone Bridge sensed output is defined by stimulus from the PCM and modulation of bridge element values by the conditioned output of an analog pressure sensor. The use of analog-to-digital-to-analog conversion in this transducer interface permits retrofitting of PCM devices having analog Wheatstone Bridge inputs with advanced patient monitoring sensors without the need for specialized modifications to the baseline PCM data collection framework. Methods disclosed herein include techniques to connect arbitrary types/numbers of analog sensors to traditional PCM systems without the need for PCM system hardware/software modifications. | 04-23-2015 |
20150112212 | TRANSDUCER INTERFACE SYSTEM AND METHOD - A transducer interface system/method allowing conversion from an analog sensor input to a standardized analog output interface is disclosed. In some preferred embodiments the system/method permits a fiber optic pressure sensor to be interfaced to a standard patient care monitor (PCM) system using standardized Wheatstone Bridge analog interface inputs. Within this context the Wheatstone Bridge sensed output is defined by stimulus from the PCM and modulation of bridge element values by the conditioned output of an analog pressure sensor. The use of analog-to-digital-to-analog conversion in this transducer interface permits retrofitting of PCM devices having analog Wheatstone Bridge inputs with advanced patient monitoring sensors without the need for specialized modifications to the baseline PCM data collection framework. Methods disclosed herein include techniques to connect arbitrary types/numbers of analog sensors to traditional PCM systems without the need for PCM system hardware/software modifications. | 04-23-2015 |
20150119730 | Method and Apparatus for Determining Cardiac Performance in a Patient with a Conductance Catheter - An apparatus for determining cardiac performance in the patient. The apparatus includes a conductance catheter for measuring conductance and blood volume in a heart chamber of the patient. The apparatus includes a processor for determining instantaneous volume of the ventricle by applying a non-linear relationship between the measured conductance and the volume of blood in the heart chamber to identify mechanical strength of the chamber. The processor is in communication with the conductance catheter. Methods for determining cardiac performance in a patient. Apparatuses for determining cardiac performance in a patient. | 04-30-2015 |
20150133799 | SYSTEMS AND METHODS FOR DETERMINING FRACTIONAL FLOW RESERVE WITHOUT ADENOSINE OR OTHER PHARMALOGICAL AGENT - Embodiments hereof relate to methods and systems for determining a pressure gradient across a lesion of a vessel without requiring the use of a pharmacological hyperemic agent. A measurement system includes at least an injection catheter and a pressure-sensing instrument or guidewire slidingly disposed through the catheter, the pressure-sensing guidewire including at least one pressure sensor configured to obtain a pressure measurement for use in determining the pressure gradient across the lesion. The catheter is configured to deliver or inject a non-pharmacological fluid, such as saline or blood, across the lesion in order to increase a flow rate there-through, thereby simulating hyperemia without the use of a pharmacological hyperemic agent. Once an increased flow rate that simulates hyperemia is achieved, the pressure sensor of the pressure-sensing guidewire may be utilized to measure the pressure gradient across the lesion in order to assess the severity of the lesion. | 05-14-2015 |
20150133800 | DUAL LUMEN CATHETER FOR PROVIDING A VASCULAR PRESSURE MEASUREMENT - A catheter is disclosed for providing a pressure measurement at a vascular lesion. The catheter includes a tubular component having dual lumens along at least a segment thereof in which a first lumen acts as a pressure inlet and a second lumen allows the catheter to be tracked over a guidewire. A plurality of openings are located along a distal segment of the tubular component that permit blood flow into the first lumen when disposed in vivo. A pressure sensor is located within a handle component of the catheter or within the tubular component to be in fluid communication with a proximal end of the first lumen. When the catheter is positioned at the vascular lesion, the first lumen fills with blood via the plurality of openings such that the pressure sensor is able to sense a pressure of the blood at a distal end of the catheter. | 05-14-2015 |
20150141853 | MULTI-SENSOR LESION ASSESSMENT DEVICE AND METHOD - An intravascular sensor delivery device can have a sensor that is used to measure a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used in combination with a medical guidewire carrying another sensor also configured to measure a physiological parameter of the patient, such as blood pressure. Data generated from the intravascular sensor delivery device sensor and the guidewire sensor can be used to determine a characteristic of interest for the vascular structure under investigation. For example, the data can be used to calculate a pressure distal to pressure proximal ratio across a stenotic lesion in order to assess the severity of the lesion. | 05-21-2015 |
20150148693 | Sensor Mounting Assembly for Sensored Guidewire and Associated Devices, Systems, and Methods - Intravascular devices, systems, and methods are disclosed. In some embodiments, a guidewire system for treating a patient includes an internal sensor mount having a body and a first cutout extending through a wall of the body; a core wire secured to the internal sensor mount; a sensor assembly for detecting a physiological characteristic of a patient secured to the internal sensor mount; an external housing disposed about the internal sensor mount and including an opening in communication with the cutout of the internal sensor mount; a proximal flexible member secured to at least one of the internal sensor mount and the external housing; a first distal flexible member secured to at least one of the internal sensor mount and the external housing; and at least one conductor electrically coupled to the sensor assembly and extending proximally beyond the internal sensor mount through the proximal flexible member. | 05-28-2015 |
20150290428 | CATHETER FOR INTRODUCTION OF MEDICATIONS TO THE TISSUES OF A HEART OR OTHER ORGAN - A positionable, direct-injection catheter that can access a specific region of the heart or other organ. The catheter is provided with one or two needle shafts, which may be located within respective sheaths that extend axially along the interior of the lumen of a main catheter shaft. Each needle shaft carries, at a distal end thereof a penetrable element that is normally retracted, but is subsequently deployed by a trigger. Each extended needle is curved to enter the organ wall in a flattened trajectory that both reduces the chance of puncture through the wall and anchors the needles into the wall during injection. A plurality of apertures which provide for more complete agent delivery rapidly, while maintaining a low delivery velocity to avoid the problems caused by high velocity delivery. The needles are typically arranged to exit the tip at contralateral orientations relative to each other. | 10-15-2015 |
20150297138 | INTRAVASCULAR DEVICES, SYSTEMS, AND METHODS HAVING SEPARATE SECTIONS WITH ENGAGED CORE COMPONENTS - Intravascular devices, systems, and methods are disclosed. In some instances, the intravascular device is a guide wire that includes separate sections with engaged core components. For example, a sensing guide wire can include a proximal portion having a proximal core member and at least one proximal electrical conductor and a distal portion coupled to the proximal portion, the distal portion having a distal core member, a sensing element, and at least one distal electrical conductor coupled to the sensing element, wherein engagement structures of the proximal and distal core members are engaged and wherein the at least one distal electrical conductor is coupled to the at least one proximal electrical conductor such that the at least one proximal electrical conductor is in electrical communication with the sensing element. Methods of making, manufacturing, and/or assembling such intravascular devices and associated systems are also provided. | 10-22-2015 |
20150305633 | Catheter With Inner Surface Pressure Sensor for Providing a Vascular Pressure Measurement for Determining Fractional Flow Reserve - A catheter includes an elongate shaft including a proximal portion and a distal portion extending from the proximal portion to a distal opening at a distal end of the shaft. The proximal portion defines a proximal guidewire lumen and has a first outer diameter. The distal portion defines a distal guidewire lumen in communication with the proximal guidewire lumen and has a second outer diameter smaller than the first outer diameter. A pressure sensor is coupled to the proximal portion such that the pressure sensor faces the proximal guidewire lumen. When the catheter is tracked to a treatment site within the vasculature, the pressure sensor is disposed proximal the treatment site, the distal opening is disposed distal to the treatment site, and the distal guidewire lumen fills with blood such that the pressure sensor senses a pressure of the blood at the distal end of the shaft. | 10-29-2015 |
20150351644 | PRESSURE SENSING GUIDEWIRE SYSTEMS WITH REDUCED PRESSURE OFFSETS - Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a medical device for measuring blood pressure. The medical device may include an elongated shaft having a proximal region and a distal region. An optical fiber may extend along the proximal region. An optical pressure sensor may be coupled to the optical fiber. The medical device may also include a tubular member having a proximal end disposed adjacent to the optical pressure sensor and a distal portion extending along the distal region of the shaft. | 12-10-2015 |
20150351645 | PHYSIOLOGICAL SENSOR DELIVERY DEVICE AND METHOD - Methods of measuring Fractional Flow Reserve (FFR) including advancing a sensor delivery device within a guiding catheter to a location of interest, the sensor delivery device comprising a distal sleeve including a distal sensor and a proximal sensor, advancing only a distal portion of the distal sleeve outside of the guiding catheter such that the distal sensor is outside of the guiding catheter and downstream of the location of interest and the proximal sensor is inside of the guiding catheter, measuring a distal fluid pressure with the distal sensor distal to the location of interest, measuring a reference fluid pressure with the proximal sensor inside of the guiding catheter, and calculating FFR. One or both of the proximal and distal sensor may be comprised of a material having a low thermal coefficient. | 12-10-2015 |
20150359438 | PRESSURE MEASURING CATHETER HAVING REDUCED ERROR FROM BENDING STRESSES - Bending stresses experienced by a pressure sensor mounted to a fractional flow reserve catheter when tracking the catheter through the vasculature creates a distortion of the sensor resulting in an incorrect pressure reading or bend error. In order to isolate the sensor from bending stresses, the sensor is mounted with one end coupled to the distal end of the shaft while the other end of the sensor is not coupled to the catheter so that a portion of the sensor is spaced apart from the distal end of the shaft. | 12-17-2015 |
20160000340 | RAPID CENTRAL VENOUS PRESSURE MONITOR - A device used to quickly measure central venous pressure is disclosed. Compared to current systems, the JVPM is easier to use, less expensive, and faster in providing the needed information to determine both the course of treatment and the proper positioning of the inserted catheter. As a physically smaller device that remains within the sterile operative field, the JVPM is also less likely to introduce infecting organisms into the body. | 01-07-2016 |
20160000341 | INTRAVASCULAR PRESSURE DROP DERIVED ARTERIAL STIFFNESS AND REDUCTION OF COMMON MODE PRESSURE EFFECT - In some embodiments, a method and/or device are disclosed for measuring a pressure drop over a portion of a body lumen. Optionally, the pressure drop for two different flow conditions may be used to find the stiffness of the lumen. In some embodiments the device may be calibrated, for example by correcting for distortion, for example the common mode pressure distortion. Pressure drop and or stiffness measures may be used to evaluate a treatment procedure and/or a stenosis. | 01-07-2016 |
20160007866 | DEVICES, SYSTEMS, AND METHODS FOR ASSESSMENT OF VESSELS | 01-14-2016 |
20160015327 | DEVICES, SYSTEMS, AND METHODS AND ASSOCIATED DISPLAY SCREENS FOR ASSESSMENT OF VESSELS WITH MULTIPLE SENSING COMPONENTS - Devices, systems, and methods for visually depicting a vessel and evaluating treatment options are disclosed. The methods can include obtaining proximal pressure measurements from a proximal pressure sensing component positioned within a vessel of a patient; obtaining distal pressure measurements from multiple pressure sensing components positioned within the vessel of the patient, wherein the multiple pressure sensing components are positioned distal of the proximal pressure sensing component and are spaced along a length of the vessel; and outputting a screen display having a visual representation of the proximal and distal pressure measurements. | 01-21-2016 |
20160022153 | Interface Devices, Systems, And Methods For Use With Intravascular Pressure Monitoring Devices - Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to provide FFR measurements over a length of a vessel of interest in a small, compact device that integrates with existing proximal and distal pressure measurement systems and does not require a separate power source. | 01-28-2016 |
20160022154 | SYSTEM INCLUDING GUIDEWIRE FOR DETECTING FLUID PRESSURE - A system for detection of blood pressure in a blood vessel includes a guide wire and a LC resonance circuit provided at a distal end of the guide wire. The resonance circuit may be a non-LC resonance circuit responsive to changes in pressure of fluid external to the guide wire such that the resonance circuit has a resonance frequency that varies in accordance with changes in pressure of the external fluid. | 01-28-2016 |
20160022215 | INTRAVASCULAR DEVICES, SYSTEMS, AND METHODS HAVING A CORE WIRE WITH MULTIPLE FLATTENED SECTIONS - The present disclosure is directed to intravascular devices, systems, and methods having a core wire with multiple flattened sections. In one aspect, a sensing guide wire is provided. The guide wire includes a first flexible elongate member; a sensing element positioned at a distal portion of the first flexible elongate member; and a second flexible elongate member coupled to the first flexible elongate member such that the second flexible elongate member extends distally from the first flexible elongate member; and wherein a distal portion of the first flexible elongate member includes at least two flattened sections, and wherein the first and second flexible elongate members are coupled along a portion of one of the at least two flattened sections. In other aspects, methods of forming a sensing guide wire are provided. | 01-28-2016 |
20160022216 | REMOTELY POWERED SENSORY IMPLANT - An implant ( | 01-28-2016 |
20160029903 | BIOLOGICAL INFORMATION MEASURING APPARATUS AND BIOLOGICAL INFORMATION MEASURING METHOD - A biological information measuring apparatus and a biological information measuring method are provided. The biological information measuring apparatus includes a pulsation information detecting unit configured to detect heartbeat information relating to a heartbeat of a subject, a blood pressure waveform measuring unit configured to measure a blood pressure waveform of the subject in an invasive manner, and a calculating unit configured to detect a cardiac cycle from the heartbeat information and to calculate, based on a detection of a maximal blood pressure value of the blood pressure waveform in the cardiac cycle, at least one of a systolic pressure of the subject, an end-diastolic pressure of the subject, an augmentation pressure of an IABP (intra-aortic balloon pumping), a systolic pressure assisted by the IABP and an end-diastolic pressure assisted by the IABP | 02-04-2016 |
20160038085 | DEVICE FOR MEASUREMENT OF PRESSURE AND FOR ADMINISTRATION OF DRUGS TO AN ANEURYSM IN A BLOOD VESSEL - The invention relates to medicine, in particular, to vascular and endovascular surgery, and can be used for assessment of the condition of an isolated space of an aneurysmal sac after implantation of a stent-graft by measuring pressure inside the sac, and for administration of drugs to an aneurysm in a blood vessel as far as necessary. The device for measurement pressure in an isolated space of an aneurysmal sac and for administration of drugs to an aneurysm in a blood vessel is made in the form of a hollow tube. The tube has side apertures and is adapted to change a shape when introduced into an aneurysm, and to fill the entire interior space of the aneurysm at its circumference. The tube is also adapted to be connected to a pressure-measuring sensor through a detachable hollow tube to measure pressure between the vessel wall and the wall of a stent-graft implanted to the blood vessel, and to administer drugs through said detachable hollow rube. The tube is made of a viscoelasticity resorbable material and coiled in a spiral form. The invention allows addressing a plurality of problems: cost saving on production of the device, facilitation of an invasion process, measurement of pressure, administration of drugs, improvement of direct and late results by ensuring thrombosing of an aneurysmal sac. | 02-11-2016 |
20160058382 | INTRAVASCULAR DEVICES, SYSTEMS, AND METHODS HAVING AN ADHESIVE FILLED FLEXIBLE ELEMENT - Intravascular devices, systems, and methods are disclosed. In some instances, the intravascular device is a guide wire with an adhesive filled flexible element. For example, in some implementations a sensing guide wire includes a flexible elongate member; a flexible element extending distally from the flexible elongate member; a core member extending within a lumen of the flexible element; at least one flexible adhesive filling at least a portion of the lumen between the core member and the flexible element along a length of the flexible element; and a sensing element positioned distal of the flexible element. Methods of making, manufacturing, and/or assembling such intravascular devices and associated systems are also provided. | 03-03-2016 |
20160058977 | INTRAVASCULAR DEVICES, SYSTEMS, AND METHODS HAVING AN ADHESIVE FILLED DISTAL TIP ELEMENT - Intravascular devices, systems, and methods are disclosed. In some instances, the intravascular device is a guide wire with an adhesive filled distal coil. For example, in some implementations a sensing guide wire includes a flexible elongate member; a sensing element coupled to a distal portion of the flexible elongate member; and a flexible element filled with a flexible adhesive extending distally from the sensing element. Methods of making, manufacturing, and/or assembling such intravascular devices and associated systems are also provided. | 03-03-2016 |
20160067005 | PRESSURE WIRE DETECTION AND COMMUNICATION PROTOCOL FOR USE WITH MEDICAL MEASUREMENT SYSTEMS - One aspect of the present disclosure involves a method. The method includes retrieving, from a diagnostic medical device, identification information that identifies a feature of the diagnostic medical device. A proprietary signal is generated in response to the identification information. The proprietary signal is sent to a medical measurement system to facilitate an unlocking of one or more programs to be executed on the medical measurement system. Another aspect of the present disclosure involves a method. The method includes detecting, through an electronic interface device, a coupling of a remote diagnostic medical device. Thereafter, a proprietary signal is received from the electronic interface device. An identity feature of the remote diagnostic medical device is ascertained based on the proprietary signal. One or more programs are unlocked for execution if the identity feature of the remote diagnostic medical device matches a predetermined identity feature. | 03-10-2016 |
20160067456 | PRESSURE GUIDE WIRE PULLBACK CATHETER - Intravascular devices, systems, and methods are provided. In some embodiments, the intravascular devices are catheters with a plurality of openings in a distal portion to facilitate taking pressure measurements from within a lumen of the catheter. The intravascular device includes a tubular member that has a proximal portion and a distal portion; a lumen extending from the proximal portion to the distal portion along a longitudinal axis of the tubular member, the lumen sized and shaped to receive a pressure sensing device; and openings spaced along the distal portion of the tubular member, the openings sized and shaped to provide fluidic communication between the lumen and a region surrounding the tubular member to allow the pressure sensing device to measure an ambient pressure of the region surrounding the tubular member from within the lumen. An intravascular system and a method for obtaining pressure measurements are also provided. | 03-10-2016 |
20160073957 | INTRAVASCULAR DEVICES, SYSTEMS, AND METHODS HAVING A SENSING ELEMENT EMBEDDED IN ADHESIVE - Intravascular devices, systems, and methods are disclosed. In some instances, the intravascular devices are guide wires that include a distal sensing element mounted partially within a housing and embedded and/or surrounded by a flexible adhesive. For example, in some implementations a sensing guide wire includes a flexible elongate member; a housing coupled to the flexible elongate member; a flexible element extending distally from the housing; and a sensing element coupled to the flexible elongate member such that a proximal portion of the sensing element is positioned within the housing and a distal portion of the sensing element is positioned within the flexible element. A flexible adhesive can embed or surround the distal portion of the sensing element positioned within the flexible element. Methods of making, manufacturing, and/or assembling such intravascular devices and associated systems are also provided. | 03-17-2016 |
20160073959 | HYPOVOLEMIA/HYPERVOLEMIA DETECTION USING PERIPHERAL INTRAVENOUS WAVEFORM ANALYSIS (PIVA) AND APPLICATIONS OF SAME - Aspects of the invention relates to systems and methods for hypovolemia and/or hypervolemia detection of a living subject using peripheral intravenous waveform analysis. In one embodiment, the method includes: acquiring, from a vein of the living subject, peripheral venous signals; performing a spectral analysis on the acquired peripheral venous signals to obtain a peripheral venous pressure frequency spectrum; and performing a statistical analysis on amplitudes of peaks of the peripheral venous pressure frequency spectrum to determine the blood volume status of the living subject in real time. Specifically, at least two peaks, respectively corresponding to a first frequency and a second frequency, are obtained on the peripheral venous pressure frequency spectrum. Amplitude change of the second peak is used to determine the blood volume status of the living subject. Hemorrhage may be detected when a significant amplitude decrease is detected from the second baseline peak to the second peak. | 03-17-2016 |
20160073972 | BEDSIDE CONTROLLER FOR ASSESSMENT OF VESSELS AND ASSOCIATED DEVICES, SYSTEMS, AND METHODS - Devices, systems, and methods for evaluating a vessel of a patient are provided. The method includes outputting, to a touch-sensitive display of a bedside controller, a screen display including: a visual representation of a first pressure ratio of pressure measurements obtained by first and second instruments positioned within a vessel while the second instrument is moved from a distal position to a proximal position relative a stenosis and the first instrument remains stationary; and a first proximal pressure waveform and a first distal pressure waveform; receiving, through the touch-sensitive display of the bedside controller, a user touch input on the first proximal pressure waveform and/or the first distal pressure waveform identifying a time at which pressure measurements were obtained; and modifying the screen display, in response to the user touch input, to further include a visual representation of the obtained pressure measurements corresponding to the identified time. | 03-17-2016 |
20160081564 | MICROCATHETER SENSOR DESIGN FOR MINIMIZING PROFILE AND IMPACT OF WIRE STRAIN ON SENSOR - A catheter, such as a fractional flow reserve catheter, includes an elongate shaft having a pressure sensing wire extending to the distal portion of the elongate shaft. The wire has a pressure sensor mounted on the distal end for measuring a pressure of a fluid within lumen of vessel. The pressure sensor wire is disposed within a pocket formed adjacent to the pressure sensor thereby minimizing the profile of the catheter. Bending stresses experienced by a pressure sensor mounted to a fractional flow reserve catheter when tracking the catheter through the vasculature creates a distortion of the sensor resulting in an incorrect pressure reading or bend error. In order to isolate the sensor from bending stresses, the sensor is spaced apart from the pressure sensor wire to allow the pressure sensor and the pressure sensor wire to move independently from one another. | 03-24-2016 |
20160095523 | COAXIAL DUAL LUMEN PIGTAIL CATHETER - A coaxial dual lumen pigtail catheter utilizes coaxial construction incorporating a thin wall guiding catheter technology for the outer lumen and using a strong braided diagnostic technology for the central lumen to accommodate high-pressure injections. The catheter includes a manifold body to provide for connection to each of the dual lumens. The distal end of the coaxial dual lumen pigtail catheter tapers to a more flexible portion that is perforated by spiral side holes to provide for more undistorted pressure readings in the left ventricle. The coaxial dual lumen pigtail catheter also utilizes proximal straight sideholes at the end of the dual lumen portion and a taper between the dual lumen portion and the single lumen portion. | 04-07-2016 |
20160106373 | INTRAVASCULAR SENSING METHOD AND SYSTEM - Methods and systems for calculating a corrected Fractional Flow Reserve. Methods include delivering a pressure sensing device including a pressure sensor to a location in an artery having a stenosis, positioning the pressure sensor distal to the stenosis, measuring the distal pressure, measuring the proximal pressure, and calculating a corrected Fractional Flow Reserve using the measured proximal and distal pressures and applying a correction factor or correction equation. The correction factor or correction equation corrects for changes in the measured distal pressure caused by a presence of the pressure sensing device. A data set of correction factors or correction equations may be stored in a memory component of the system. The corrected Fractional Flow reserve may approximate the Fractional Flow Reserve that would be obtained if a different sized device was used to measure the distal pressure, such as a pressure sensing guidewire having a 0.014 inch outer diameter. | 04-21-2016 |
20160120415 | SYSTEM AND METHOD FOR FFR GUIDEWIRE RECOVERY - A kit for coronary treatment comprising a pressure sensing guidewire that includes a pressure sensor for measuring pressure within a patient's vasculature. A sheath comprising a tube having a proximal end and a distal end and defining an internal lumen sized for receiving the pressure sensing guidewire; a hemostasis valve positioned over the proximal end of the tube; a cylindrical element attached to the distal end of the tube, the cylindrical element having an internal lumen sized for receiving a conventional guidewire; wherein the pressure sensing guidewire is configured to be slideably insertable into the tube from the proximal end of the tube; and further wherein, the tube is configured to permit the pressure sensing guidewire, including the pressure sensor, to freely slide distally and proximally within the tube at the election of a user. | 05-05-2016 |
20160121085 | INTRAVASCULAR DEVICES, SYSTEMS, AND METHODS HAVING A RADIOPAQUE PATTERNED FLEXIBLE TIP - Intravascular devices, systems, and methods are disclosed. In some instances, the intravascular device is a guide wire with distal tip element having a radiopaque marker pattern. For example, in some implementations a sensing guide wire includes a flexible elongate member; a sensing element coupled to the flexible elongate member; a flexible tip element coupled to and extending distally from the sensing element, the flexible tip element having a first radiopaque section, a second radiopaque section, and a non-radiopaque section positioned between the first and second radiopaque sections. Methods of making, manufacturing, and/or assembling such intravascular devices and associated systems are also provided. | 05-05-2016 |
20160128583 | SYSTEM AND APPARATUS COMPRISING A MULTISENSOR GUIDEWIRE FOR USE IN INTERVENTIONAL CARDIOLOGY - A system and apparatus comprising a multisensor guidewire for use in interventional cardiology, e.g. for Transcatheter Valve Therapies (TVT), comprises a plurality of optical sensors for direct measurement of cardiovascular parameters, e.g. transvalvular blood pressure gradients and flow. A conventional outer coil contains a shaped core wire having a cross-section defining helical grooves extending along its length, which accommodate optical fibers and optical sensors within a diameter D | 05-12-2016 |
20160128584 | MEASURING DEVICE, METHOD OF MEASURING BLOOD PRESSURE, AND PROGRAM - A measuring device includes a measuring part that performs an invasive blood pressure measurement using a transducer and detects that a blood pressure measured by the invasive blood pressure measurement becomes a predetermined abnormal state during the invasive blood pressure measurement, a detecting part that detects whether or not a zero-point calibration of the transducer is being carried out, and a notification control part that controls whether or not to output an alarm based on a detection state of the detecting part when the blood pressure becomes the predetermined abnormal state. | 05-12-2016 |
20160135693 | COMPRESSION CONTROL DEVICE AND COMPRESSION CONTROL METHOD - A compression control device includes a cuff that is adapted to be wrapped to a first region of a living body, a pressure controller that controls an application pressure to be applied to the first region by the cuff, and a blood pressure obtaining section that obtains a blood pressure value from the living body. The pressure controller controls the application pressure based on the blood pressure value obtained by the blood pressure obtaining section in a state where a prescribed pressure for causing an ischemic state in a part from the first region to a periphery is applied to the first region by the cuff. | 05-19-2016 |
20160157785 | DEVICES, SYSTEMS, AND METHODS FOR DETECTING ANOMALOUS CARDIAC WAVEFORMS AND MAKING PHYSIOLOGIC MEASUREMENT CALCULATIONS - Devices, systems, and methods automatically detecting anomalous waveforms and eliminating these waveforms from physiologic measurements are disclosed. For example, in some instances a method includes collecting a pressure data from an intravascular device positioned within the vessel of the patient, the pressure data including a pressure waveform for each cardiac cycle of the patient; comparing the pressure waveform for each cardiac cycle of the patient to a reference pressure waveform to identify an anomalous pressure waveform; and calculating a pressure ratio utilizing the pressure data from the intravascular device, wherein data from the anomalous pressure waveform is excluded from the calculation. | 06-09-2016 |
20160157787 | AUTOMATED IDENTIFICATION AND CLASSIFICATION OF INTRAVASCULAR LESIONS - Devices, systems, and methods of mapping a vessel system of a patient and identifying lesions therein are disclosed. This includes a method of evaluating a vessel of a patient, the method comprising obtaining image data for the vessel of the patient, obtaining physiological measurements for the vessel of the patient, co-registering the obtained physiological measurements with the obtained image data such that the physiological measurements are associated with corresponding portions of the vessel of the patient, analyzing the co-registered physiology measurements to determine a classification of a lesion within the vessel of the patient, and outputting, to a user interface, the classification of the lesion. Other associated methods, systems, and devices are also provided herein. | 06-09-2016 |
20160166158 | SYSTEM AND METHOD OF INTEGRATING A FRACTIONAL FLOW RESERVE DEVICE WITH A CONVENTIONAL HEMODYNAMIC MONITORING SYSTEM | 06-16-2016 |
20160166211 | MEAN ARTERIAL PRESSURE ESTIMATION | 06-16-2016 |
20160183808 | METHODS, DEVICES AND SYSTEMS FOR SENSING, MEASURING AND/OR CHARACTERIZING VESSEL AND/OR LESION COMPLIANCE AND/OR ELASTANCE CHANGES DURING VASCULAR PROCEDURES - The present system is directed in various embodiments to methods, devices and systems for sensing, measuring and evaluating compliance and/or elastance in a bodily conduit. In other embodiments, the methods, devices and systems sense, measure, determine, display and/or interpret compliance and/or elastance in a bodily conduit and/or a lesion within the bodily conduit using fractional flow reserve and/or flow velocity measurements as well as resistance to flow calculations in certain embodiments. In all embodiments, the sensing, measuring, determining, displaying and/or interpreting may occur before, during and/or after a procedure performed within the bodily conduit. An exemplary conduit comprises a blood vessel and an exemplary procedure comprises a vascular procedure such as atherectomy, angioplasty, stent placement and/or biovascular scaffolding. | 06-30-2016 |
20160198958 | Intravascular Pressure Devices Incorporating Sensors Manufactured Using Deep Reactive Ion Etching | 07-14-2016 |
20160199003 | MICROCATHETER SENSOR DESIGN FOR MOUNTING SENSOR TO MINIMIZE INDUCED STRAIN | 07-14-2016 |
20160249816 | SYSTEMS, DEVICES, AND METHODS FOR DETERMINING SEVERITY OF A STENOSIS WITHIN A LUMINAL ORGAN IN THE PRESENCE OF A CATHETER | 09-01-2016 |
20160249817 | STEERABLE GUIDE WIRE WITH PRESSURE SENSOR AND METHODS OF USE | 09-01-2016 |
20160249818 | IMPLANTABLE PRESSURE SENSOR DEVICE | 09-01-2016 |
20160250444 | PRESSURE-SENSING CATHETERS AND RELATED METHODS | 09-01-2016 |
20180020930 | ESTIMATE DIASTOLIC PRESSURE | 01-25-2018 |
20190142285 | PRESSURE SENSOR, ANCHOR, DELIVERY SYSTEM AND METHOD | 05-16-2019 |