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Testing means inserted in body

Subclass of:

600 - Surgery

600300000 - DIAGNOSTIC TESTING

600481000 - Cardiovascular

600485000 - Measuring pressure in heart or blood vessel

Patent class list (only not empty are listed)

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Class / Patent application numberDescriptionNumber of patent applications / Date published
600488000 Pressure transducer structure 16
600487000 Pressure indicator includes liquid column 2
20120172732Lumen Based Pressure Sensing Guidewire System with Distortion Correction - A guidewire is disclosed that is constructed using tubular members that create a hollow lumen that runs from the proximal end of the guidewire to a window towards the distal end of the wire. This internal lumen is filled with a fluid that allows pressure exerted at the window to exert pressure at the proximal end of the guide wire proportional to the pressure exerted at the window. This pressure exerted at the proximal end of the guidewire is measured using a pressure transducer external of the guidewire. The pressure transducer converts the measured pressure into an electrical signal that is proportional to the pressure at the window. The electrical signal is manipulated to correct for errors that are due to the pressure signal traveling though the inner lumen of the guidewire to ensure the electrical signal matches the pressure exerted at the window.07-05-2012
20130023776MONITORING A PROPERTY OF THE CARDIOVASCULAR SYSTEM OF A SUBJECT - A device is configured to monitor a cardiovascular property of a subject. The device obtains measurement data from a primary pressure wave sensor arranged to detect pressure waves in an extracorporeal fluid circuit in fluid communication with the cardiovascular system of the subject. The device has a signal processor configured to generate a time-dependent monitoring signal based on the measurement data, such that the monitoring signal comprises a sequence of heart pulses, wherein each heart pulse represents a pressure wave originating from a heart beat in the subject; determine beat classification data for each heart pulse in the monitoring signal; and calculate, based at least partly on the beat classification data, a parameter value indicative of the cardiovascular property. The beat classification data may distinguish between heart pulses originating from normal heart beats and heart pulses originating from ectopic heart beats. The cardiovascular property may be an arterial status of the cardiovascular system, a degree of calcification in the cardiovascular system, a status of a blood vessel access used for connecting the extracorporeal fluid circuit to the cardiovascular system, a heart rate variability, a heart rate, a heart rate turbulence, an ectopic beat count, or an origin of ectopic beats. The device may be attached to or part of a dialysis machine.01-24-2013
Entries
DocumentTitleDate
20130030309DEVICES AND METHODS FOR TREATMENT OF HEART FAILURE AND ASSOCIATED CONDITIONS - Devices and methods of use for identification, treatment, and/or management of heart failure and/or associated conditions. Methods may include providing a baroreflex therapy system including a blood pressure sensor and a heart rate sensor, providing an implantable measurement device proximate a blood vessel of a patient, the implantable measurement device including an electrode, providing a control system coupled to the baroreflex therapy system and the implantable measurement device, the control system programmed to automatically determine an impedance of the blood vessel with the implantable measurement device over a time period of at least one cardiac cycle, determine arterial stiffness of the blood vessel based on the impedance, determine blood pressure and heart rate, and activate, deactivate or otherwise modulate the baroreflex therapy system to deliver a baroreflex therapy based on the blood pressure, heart rate and arterial stiffness.01-31-2013
20100049061SYSTEMS AND METHODS FOR PROVIDING AUDITORY FEEDBACK DURING CATHETER PLACEMENT - A system for providing auditory feedback may include a blood pressure monitor interface for acquiring pressure waveform data from a pressure transducer indicative of blood pressure readings over time. The system may further include an anatomic location annunciator for generating an audible signal from the pressure waveform data that conveys information about the anatomic location of the pressure transducer within the heart chamber or blood vessel.02-25-2010
20100113944INTERPOLATING LEFT VENTRICULAR PRESSURES - Exemplary techniques and systems for interpolating left ventricular pressures are described. One technique interpolates pressures within the left ventricle from blood pressures gathered without directly sensing blood pressure in the left ventricle.05-06-2010
20100106028METHODS AND SYSTEMS FOR RECHARGING IMPLANTABLE DEVICES - Methods, systems, and apparatus for recharging medical devices implanted within the body are disclosed. An illustrative method of recharging an implanted medical device includes delivering a charging device to a location adjacent to the implanted medical device, activating a charging element coupled to the charging device and transmitting charging energy to a receiver of the implanted medical device, and charging the implanted medical device using the transmitted charging energy from the charging device.04-29-2010
20100094144SYSTEMS AND METHODS FOR DETERMINING CARDIAC OUTPUT USING PULMONARY ARTERY PRESSURE MEASUREMENTS - Systems and methods for determining cardiac output are disclosed. An illustrative method of determining cardiac output includes sensing an arterial pressure waveform using a pressure sensor located within a pulmonary artery, identifying a valve closure time associated with the pulmonary valve using the sensed arterial pressure waveform, estimating stroke volume using the systolic portion of the arterial pressure waveform and the valve closure time, and obtaining a measure of cardiac output based on the estimated stroke volume.04-15-2010
20120184859SYSTEMS AND METHODS FOR CORROBORATING IMPEDANCE-BASED LEFT ATRIAL PRESSURE (LAP) ESTIMATES FOR USE BY AN IMPLANTABLE MEDICAL DEVICE - Various techniques are provided for assessing the reliability of left atrial pressure (LAP) estimates made by an implantable medical device based on impedance values or related electrical values. In one example, various cardioelectric and cardiomechanical parameters are used to corroborate LAP estimation in circumstances where the LAP estimates deviate from an acceptable, satisfactory or otherwise healthy range. The cardioelectric parameters include, e.g.: ST elevation; heart rate (HR); heart rate variability (HRV); T-wave alternans (TWA); QRS waveform parameters; P-wave duration; evoked response (ER) parameters; and intrinsic PV/AV/VV conduction delays. The cardiomechanical parameters include, e.g.: heart rate turbulence (HRT); cardiogenic impedance signals; heart sounds; and non-LAP blood pressure measurements, such as aortic pressure measurements. The device compares the cardioelectric and cardiomechanical parameters against corresponding baseline values to determine whether variations in the parameters corroborate the LAP estimates. If not, the LAP estimates are selectively cancelled or suspended, or the overall procedure is re-calibrated.07-19-2012
20100069763INTRAVASCULAR PRESSURE SENSOR - Pressure-sensing apparatus includes a sensor die, which is configured for percutaneous insertion through a wall of a blood vessel of a patient so as to generate an electrical signal that is responsive to a pressure in the blood vessel. A wire has a first end connected to the sensor die and a second end connected to an electronics package, which is configured for subcutaneous implantation and is connected via the wire to receive and process the electrical signal that is generated by the sensor die in order to provide an output that is indicative of the pressure.03-18-2010
20130046190Devices, Systems, and Methods for Assessing a Vessel - Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to assess the severity of a stenosis in the coronary arteries without the administration of a hyperemic agent.02-21-2013
20090093729Devices and Methods for Measurement of Vessel Elasticity and Blood Pressure - Embodiments of the invention are related to devices and methods for measuring arterial elasticity and/or blood pressure, amongst other things. In an embodiment, the invention includes an implantable medical device having a sensor element that is configured to engage a vessel of a patient. The sensor element is further configured to generate a signal in response to bending of the sensor element, where bending occurs as a result of changes in the pressure within the vessel. The implantable medical device further includes a controller in signal communication with the sensor element, where the controller is configured to store information regarding the signal generated by the sensor element. Other embodiments are also included herein.04-09-2009
20090270742DEVICES FOR FIXING A SENSOR IN A LUMEN - Apparatus for positioning at least one sensor in a body lumen, the apparatus including a fixation element, a sensor, and a connecting element that connects the sensor to the fixation element, the connecting element extending at least partially into the lumen so that the sensor is located radially inward from a wall of the lumen.10-29-2009
20090270741Coronary Venous System Pressure Sensing - Disclose herein is a method of measuring pressures in a coronary sinus. In one embodiment, the method includes: introducing a distal portion of a lead or tool into the coronary sinus, wherein the distal portion includes first and second pressure sensors and at least one selectably expandable member; expanding the at least one expandable member such that the first and second sensors are isolated from each other within the coronary sinus; and taking pressure measurements with the first and second sensors when isolated from each other.10-29-2009
20090270740ENHANCED PRESSURE SENSING SYSTEM AND METHOD - An enhanced pressure sensing system and method use an external diaphragm to address issues involved with accurate and prolonged measurement of fluid pressure, such as of blood flowing in a vascular structure. Some external diaphragms include a metallized layer or other highly impermeable layer to furnish a high degree of seal at least near to hermetic grade. As temperature of the intermediary fluid changes, the external diaphragm is able to move in a direction that minimizes differential pressure across the external diaphragm over an operational temperature range thereby reducing pressure change of the intermediary fluid due to change in temperature of the intermediary fluid. Relatively smooth hydrodynamic surfaces can be used as well as a bi-layer construction.10-29-2009
20130165802SYSTEM AND METHOD FOR DISCRIMINATING HYPERVOLEMIA, HYPOVOLEMIA AND EUVOLEMIA USING AN IMPLANTABLE MEDICAL DEVICE - Techniques are provided for use by an implantable medical device or diagnostic sensor for detecting and discriminating euvolemia, hypervolemia and hypovolemia. In one example, the device detects a pressure signal within the patient representative of changes in cardiac pressure overall several cardiac cycles. The device generates separate time-domain and frequency-domain representations of the pressure signal and then discriminates among euvolemia, hypervolemia and hypovolemia within the patient based on an analysis of the time-domain and the frequency-domain representations of the signal. Depending upon the capabilities of the device, suitable warnings may be generated to alert the patient or caregiver. Diuretics or other medications can be titrated to address abnormal fluid conditions such as a fluid overload during hypervolemia. Techniques for detecting a pressure alternans pattern indicative of imminent decompensation are also described.06-27-2013
20090326390Pressure and Oxygen Saturation Monitoring Devices and Systems - Pressure and oxygen saturation monitoring devices and systems are disclosed. The devices, or portions thereof, can be implanted within a subject for monitoring blood pressure and oxygen saturation.12-31-2009
20110301474Heart Failure Monitor Quicklook Summary for Patient Management Systems - Continuous remote monitoring of patients based on data obtained from an implantable hemodynamic monitor provides an interactive patient management system. Using network systems, patients are remotely monitored to continuously diagnose and treat heart-failure conditions. A screen displayable summary provides continuous feedback and information to physicians, patients and authorized third parties. The quick look summary includes various sites and presentation tailored to match the patients' and physicians' needs. The quick look summary further includes intelligent features that understand and retain the user's interests, preferences and use patterns. Patients, physicians and other caregivers are seamlessly connected to monitor and serve the chronic needs of heart-failure patients in a reliable and economic manner.12-08-2011
20110301473SYSTEM AND METHOD FOR ASSESSING CARDIAC PERFORMANCE THROUGH CARDIAC VIBRATION MONITORING - A system and method for assessing cardiac performance through cardiac vibration monitoring is described. Cardiac vibration measures are directly collected through an implantable medical device. Cardiac events including at least one first heart sound reflected by the cardiac vibration measures are identified. The first heart sound is correlated to cardiac dimensional measures relative to performance of an intrathoracic pressure maneuver. The cardiac dimensional measures are grouped into at least one measures set corresponding to a temporal phase of the intrathoracic pressure maneuver. The at least one cardiac dimensional measures set is evaluated against a cardiac dimensional trend for the corresponding intrathoracic pressure maneuver temporal phase to represent cardiac performance.12-08-2011
20110288422ESTIMATION OF PRESSURE AT REMOTE SITE BY BRACHIAL OSCILLOMETRIC WAVE FROM ANALYSIS - The present invention relates to a device and a method for estimating central systolic blood pressure based on oscillometric signals from brachial artery by the use of a pressure cuff.11-24-2011
20110201949ANCHORED IMPLANTABLE PRESSURE MONITOR - An anchored implantable pressure monitor.08-18-2011
20100113943SYSTEM AND METHOD FOR SIMULTANEOUS CENTRAL AND BRACHIAL ARTERIAL PRESSURE MONITORING - An implantable medical device system and corresponding method to monitor blood pressure by transforming a measured pressure signal to estimate a blood pressure metric or waveform corresponding to a target site. An implantable sensor generates a signal corresponding to blood pressure at a first arterial branch location and a processor receiving the signal applies a transfer function to the signal to derive a blood pressure metric or waveform at a target site.05-06-2010
20100113945HEMODYNAMIC MONITORS AND SYSTEMS AND METHODS FOR USING THEM - Systems and methods are provided for determining the pressure-volume relationship for one or more chambers of a heart, e.g., to guide pharmacologic or other treatment of congestive heart failure. An implantable device includes a catheter including a distal end sized for introduction into a chamber of a heart, a pressure sensor for measuring pressure within the chamber, and a sensor for measuring fluid volume within the chamber. A processor coupled to the catheter obtains pressure data from the pressure sensor and fluid volume data from the volume sensor. The processor approximates fluid volume within the chamber as a function of time and determines one or more pressure-volume loops based upon the pressure data and the fluid volume. In one embodiment, the catheter is a lead and a controller which identifies changes in determinants of cardiac output. Changes in medical therapy are guided by pressure volume loop data generated.05-06-2010
20120108987IMPLANTABLE SYSTEMIC BLOOD PRESSURE MEASUREMENT SYSTEMS AND METHODS - Implantable systems, and methods for use therewith, for monitoring arterial blood pressure on a chronic basis are provided herein. A first signal indicative of electrical activity of a patient's heart, and a second signal indicative of mechanical activity of the patient's heart, are obtained using implanted electrodes and an implanted sensor. By measuring the times between various features of the first signal relative to features of the second signal, values indicative of systolic pressure and diastolic pressure can be determined. In specific embodiments, such features are used to determine a peak pulse arrival time (PPAT), which is used to determine the value indicative of systolic pressure. Additionally, a peak-to-peak amplitude at the maximum peak of the second signal, and the value indicative of systolic pressure, can be used to determine the value indicative of diastolic pressure.05-03-2012
20120108986Implantable Medical Sensor and Fixation System - An implantable medical device, such as a sensor for monitoring a selected internally detectable physiological parameter of a patient, is attached to a fixation member that is deployable within the patient to position and orient the sensor to enable it to perform its function. The fixation member may be configured to lie in a single plane when deployed or may be tubular in shape. The attachment of the housing and fixation member includes providing the fixation member with a linear attachment strut that is non-circular in cross section and providing the housing with external members that define an elongate channel, non-circular in cross section and receptive to the attachment strut. The attachment strut can be inserted transversely into the channel and the external member can be crimped over the strut to secure the housing and fixation member together.05-03-2012
20090299198ESTIMATING PULMONARY ARTERY DIASTOLIC PRESSURE - A method for estimating pulmonary artery diastolic pressure, for a single heart beat, includes establishing a time window for sampling and storing pressure data points from a right ventricular pressure transducer. The time window may be established according to predetermined parameters and/or according to one or more triggering events. An approximate time at which the pulmonary artery valve opens is determined, either via the sampled pressure data points, or via another form of more direct monitoring, during the time window, in order to estimate the pulmonary artery diastolic pressure. A plurality of sets of N pressure data points may be collected, from the sampled data, and, for each collected set, a weighted sum is calculated. Each weighted sum may be employed to evaluate a quality of the sampled data and/or to estimate the pulmonary artery diastolic pressure, if the more direct monitoring of the pulmonary artery valve is not employed.12-03-2009
20080275350SYSTEM FOR ANCHORING AN IMPLANTABLE SENSOR IN A VESSEL - A system and a method of disposing a second sensor module overlying a first sensor module system is described. A first assembly including an expandable anchor and a sensor module is at least partially overlapped by a second assembly including an expandable anchor and a sensor module. If necessary or desired, the functions of the second sensor module can replace the functions of the first sensor module. The sensor module may include a blood pressure sensor.11-06-2008
20120296222Implantable Medical Sensor and Anchoring System - A medical device adapted to be implanted in a vessel of a human body includes a housing that contains means for performing medical functions and an anchor for supporting the housing in an intended location and orientation within the vessel. The anchor is expandable from a low profile configuration adapted for delivery to an expanded configuration for engagement with the vessel wall. The anchor and delivery device are adapted to enable the medical device to be retrieved and repositioned or removed from the vessel. The anchor is adapted to apply sufficient force against the vessel wall to maintain the anchor in place but less force than that required to provide scaffolding support for the vessel.11-22-2012
20080312543MEASUREMENT OF PULMONARY HYPERTENSION FROM WITHIN THE AIRWAYS - This is directed to methods and devices suited for airway based measurements of pressure in a pulmonary artery. A device is advanced into an airway and in the vicinity of the pulmonary artery. Physical properties of the pulmonary artery are observed through the airway wall using one or more minimally invasive modalities. In a variation, a bronchial balloon catheter measures pressure of the pulmonary artery.12-18-2008
20080281210Arterial pressure sensing device - An implantable medical device including a tubular housing defining a passage between a proximal end and a distal end of the housing. The passage providing fluid communication through the housing. A sensing unit is positioned within the passage and coupled to the housing. The sensing unit is configured to sense at least one of a physical, chemical, and physiological parameter within the passage.11-13-2008
20110208067Vascular patency management using electric fields - The invention relates to the management of vascular patency by the use of implanted devices delivering one or more energies to a target vascular tissue wherein such energy delivery sources are substantially located in the vicinity of a target vascular region. The invention preferably employs electric currents as energy and utilizes one or more electrodes positioned in the vicinity of a target region and one or more electrodes located elsewhere. Such devices may be useful in the management of stenotic lesion formation adversely associated with a loss of patency in a variety of disease states or conditions, including vascular patency needed for hemodialysis used in the treatment of kidney failure.08-25-2011
20090247884CEREBRAL PERFUSION AUGMENTATION - Methods are provided for partial aortic occlusion for cerebral perfusion augmentation in patients suffering from global or focal cerebral ischemia. The descending aorta is accessed. A device is then located downstream from the takeoff of the brachiocephalic artery. The device is operated to at least partially obstruct blood flow in the aorta during systole and diastole. A physiologic parameter can be measured. The device can then be adjusted to modify the degree of obstruction based on the measured physiologic parameter.10-01-2009
20090024042METHOD AND SYSTEM FOR MONITORING VENTRICULAR FUNCTION OF A HEART - A method for monitoring a right atrial pressure (RAP) and a left atrial pressure (LAP) for diagnosis of a heart condition includes positioning a transseptal device with respect to a pulmonary artery to monitor at least one flow characteristic of blood through the pulmonary artery. The transseptal device is configured to generate one or more signals representative of the at least one flow characteristic. A right ventricular end diastolic pressure (RVEDP) and a left ventricular end diastolic pressure (LVEDP) are detected to facilitate monitoring the heart condition.01-22-2009
20090062667Implantable Systemic Blood Pressure Measurement Systems and Methods - Implantable systems, and methods for use therewith, for monitoring arterial blood pressure on a chronic basis are provided herein. A first signal indicative of electrical activity of a patient's heart, and a second signal indicative of mechanical activity of the patient's heart, are obtained using implanted electrodes and an implanted sensor. By measuring the times between various features of the first signal relative to features of the second signal, values indicative of systolic pressure and diastolic pressure can be determined. In specific embodiments, such features are used to determine a peak pulse arrival time (PPAT), which is used to determine the value indicative of systolic pressure. Additionally, a peak-to-peak amplitude at the maximum peak of the second signal, and the value indicative of systolic pressure, can be used to determine the value indicative of diastolic pressure.03-05-2009
20090082678Pressure wire assembly - Pressure sensor wire assembly for measuring pressure inside a body of a patient, the assembly comprises a pressure sensor element for measuring pressure and to generate a pressure sensor signal in response of said pressure, and a pressure sensor wire having said pressure sensor element at its distal portion, and adapted to be inserted into the body in order to position the sensor element within the body. In addition is arranged a sensor signal adapting circuitry, being an integrated part of said assembly, wherein the pressure sensor signal is applied to the adapting circuitry that is adapted to automatically generate an output pressure signal, related to the sensor signal, in a standardized format such that the measured pressure is retrievable by an external physiology monitor. The assembly further comprises an external pressure sensor arranged at the assembly to measure the pressure outside the patient's body and to generate external pressure values in dependence thereto, the external pressure values are applied to a pressure compensation means, in the assembly, adapted to generate a compensation value reflecting the external pressure variation during a measurement procedure, wherein the output pressure signal is compensated by said compensation value prior to the output pressure signal being applied to the external physiology monitor.03-26-2009
20080262361SYSTEM AND METHOD FOR CALIBRATING CARDIAC PRESSURE MEASUREMENTS DERIVED FROM SIGNALS DETECTED BY AN IMPLANTABLE MEDICAL DEVICE - Various techniques are provided for calibrating and estimating left atrial pressure (LAP) using an implantable medical device, based on impedance, admittance or conductance parameters measured within a patient. In one example, default conversion factors are exploited for converting the measured parameters to estimates of LAP. The default conversion factors are derived from populations of patients. In another example, a correlation between individual conversion factors is exploited to allow for more efficient calibration. In yet another example, differences in thoracic fluid states are exploited during calibration. In still yet another example, a multiple stage calibration procedure is described, wherein both invasive and noninvasive calibration techniques are exploited. In a still further example, a therapy control procedure is provided, which exploits day time and night time impedance/admittance measurements.10-23-2008
20090105598Calibration of in vivo blood pressure sensors - A method for performing an in-vivo calibration of a blood pressure sensor that is associated with an in-vivo balloon system. The method involves monitoring a patient's blood pressure by observing the system gas pressure while at the same time monitoring the patient's blood pressure through the sensor. The blood pressure measurements obtained by monitoring the system gas pressure are used as reference, or “true,” blood pressure measurements, and an “offset” is determined between the reference blood pressure measurements and the blood pressure measurements obtained through the sensor. The offset can be stored in a memory, which may also store sensor sensitivity data. The offset and/or sensitivity data may be used to adjust future measurements obtained from the sensor, thereby generating calibrated sensor measurements.04-23-2009
20090209869PRESSURE RECOVERY INDEX TO ASSESS CARDIAC FUNCTION - Determining an index for assessing cardiac function. In an embodiment, a method includes receiving ventricular pressure data during an invasive cardiac procedure, wherein the received pressure data includes a diastatic ventricular pressure value, a minimum ventricular pressure value, and a predefined fiducial marker pressure value. An index value is calculated by comparing a first pressure difference to a second pressure difference. The first pressure difference represents the difference between the received diastatic ventricular pressure value and the received minimum ventricular pressure value. The second pressure difference represents the difference between the received fiducial marker pressure value and the received minimum ventricular pressure value. The index value is provided to a health care provider to assess early diastolic cardiac function.08-20-2009
20100262021Hypertension system and method - Disclosed are hypertension systems and related methods that include a blood pressure sensor located or implanted under the skin of a patient, and electronics, which may have the size and shape of a wrist watch, for example, that monitors the blood pressure of the patient by communicating with the implanted sensor.10-14-2010
20110060230DETERMINATION OF DIASTOLIC HEART FAILURE - An exemplary method includes detecting a change in state of a cardiac valve, detecting elongation of the left ventricle substantially along its major axis, determining a time difference between the change in state of the cardiac valve and the elongation of the left ventricle and, based at least in part on the time difference, deciding whether a diastolic abnormality exists. Other exemplary methods, devices, systems, etc., are also disclosed.03-10-2011
20110060229Systems, methods, and devices for facilitating access to target anatomical sites or environments - Methods and structures for detecting a physiologic parameter of a target anatomical environment. The device including a housing with a distal portion first port couplable to a probe and a proximal portion; and a sensing unit, a processing unit, and an output unit carried by the housing, the output unit configured to output a reporting signal based on the determined physiologic parameter value such as pressure; the sensing unit, processing unit, and output unit being disposed substantially between the first port and the proximal portion of the housing.03-10-2011
20100222686MINIATURE WIRELESS BIOMEDICAL TELEMETRY DEVICE - Provided herein are embodiments of a miniature wireless biomedical telemetry device along with systems and methods for its use. A miniature amplifier and transmitter allow recording of physiological signals from small animals, such as rats, mice and birds, as well as humans. The device is positioned externally and is easily replaceable, as is its battery, so surgical complications and other problem problems are minimized.09-02-2010
20130218032GUIDEWIRE WITH INTERNAL PRESSURE SENSOR - The present document describes a pressure guidewire comprising: a shaft tube with a proximal section; a middle section extending from the proximal section of the shaft tube, the middle section having greater flexibility than the proximal section; an inner hypotube installed substantially within the middle section for optimal mechanical properties; a pressure sensor with a communication means routed through the middle section and the proximal section; and a sensor housing for receiving the pressure sensor. There are also described methods for joining the inner hypotube to the shaft tube.08-22-2013
20110028852Implantable Pressure Sensor with Membrane Bridge - An implantable pressure sensor having improved bend error performance is provided having a capsule housing a pressure sensing device, wherein the capsule includes an opening that allows the pressure sensing device to obtain pressure measurements from an environment surrounding the capsule. A rigid bridge is attached to the capsule so as to extend across the opening of the capsule. The bridge includes at least one opening that exposes the pressure sensing device to the surrounding environment. The rigidity of the bridge functions to prevent deformations from bending forces that are exerted on the sensor and also functions to divert loads from such bending forces away from the pressure sensing device to instead travel through the bridge, which in turn resists deformation. A fill material may be situated between the bridge and capsule so as to prevent bodily fluid or tissue from building up in the sensor under the bridge.02-03-2011
20090275843SYSTEM AND METHOD OF DETERMINING ARTERIAL BLOOD PRESSURE AND VENTRICULAR FILL PARAMETERS FROM VENTRICULAR BLOOD PRESSURE WAVEFORM DATA - A system and method of determining hemodynamic parameters uses sensed ventricular blood pressure during a portion of ventricular pressure waveform following peak pressure. An estimated arterial diastolic pressure is based upon an amplitude of the sensed ventricular pressure corresponding to a time at which a first derivative of ventricular pressure as a function of time is at a minimum (dP/dt11-05-2009
20100312126Calibration of in vivo blood pressure sensors - A method for performing an in-vivo calibration of a blood pressure sensor that is associated with a balloon of an in-vivo balloon system, the sensor and balloon being associated such that the sensor is in-vivo when the balloon is in-vivo. The balloon is inflated so that a gas pressure in the balloon system is indicative of a patient's blood pressure. The patient's blood pressure is monitored through two channels, the gas pressure and the sensor. The blood pressure measurements obtained by monitoring the gas pressure are used as reference, or “true,” blood pressure measurements to determine a mathematical relationship between blood pressure measurements obtained through the sensor and the reference blood pressure measurements. In this manner, future blood pressure measurements obtained through the sensor can be modified according to the mathematical relationship to generate calibrated blood pressure measurements.12-09-2010
20110245693INTRAVASCULAR PRESSURE SENSING - Devices, systems, and methods associated with pressure sensing are described herein. In one or more embodiments, an intravascular pressure sensing device includes a magnetic sensing element fixedly positioned within a sensor tube, a magnet located a distance from the magnetic sensing element within the sensor tube, the magnet movably positioned within the sensor tube via a ferrofluid magnetically attached to the magnet, and an amount of compressible fluid sealed between the magnetic sensing element and the magnet.10-06-2011
20090312650IMPLANTABLE PRESSURE SENSOR WITH AUTOMATIC MEASUREMENT AND STORAGE CAPABILITIES - Methods for activating implantable medical devices within a patient's body are disclosed. An illustrative method includes activating an implantable medical device from a low-power state to an awake state in response to a scheduled time event, sensing one or more pressure measurements within the body, computing an average pressure measurement based on the sensed pressure measurements, storing the average pressure measurement within a memory of the implantable medical device, and then returning the device to the low-power state. A triggering event such as the detection of patient activity or motion can also be used to activate the implantable medical device between the low-power state and an active state.12-17-2009
20100210955DEVICE FOR TREATMENT OF ANEURYSM - In a method, system and device for treating aneurysm a member is placed around the aneurysm, the aneurysm can be treated and monitored. The member can comprise a sensor placed in relation to a wall portion of the aneurysm for generating a signal corresponding to a parameter related to the aneurysm or the treatment of the aneurism. For example the size of the aneurysm such as the diameter of the aneurysm can be monitored. Hereby changes in the aneurism can be detected and information about the changes of the aneurysm can be used when determining how to treat the aneurysm.08-19-2010
20090048524IMPLANTABLE PRESSURE MEASURING UNIT AND CONFIGURATION FOR INTERNAL PRESSURE MEASUREMENT IN A BLOOD VESSEL - Implantable pressure measuring unit for internal pressure measurement in a blood vessel or heart of a patient, having a pressure sensor having electrical signal output, fixing means adapted to the intended measurement location for fixing the pressure sensor, a power supply unit of the pressure sensor, a signal detection unit connected by a line to the signal output of the pressure sensor, and a transmitting unit connected to a measurement data output of the signal detection unit, in particular for wireless transmission of measurement data to an analysis unit, in particular outward from the patient body.02-19-2009
20110178416DEVICES AND METHODS FOR CONTROL OF BLOOD PRESSURE - Apparatus and methods are described including an implantable device shaped to define (a) at least two artery-contact regions, the artery-contact regions comprising struts that are configured to stretch an arterial wall by applying pressure to the arterial wall, and (b) at least two crimping regions that comprise locking mechanisms configured to prevent the crimping regions from becoming crimped due to pressure from the wall of the artery on the artery-contact regions. The crimping regions are configured to be crimped during insertion of the device, via a catheter, by the locking mechanisms being unlocked during insertion of the device. Other embodiments are also described.07-21-2011
20110178417METHODS FOR DETERMINING FRACTIONAL FLOW RESERVE - Devices, systems, and methods for determining fractional flow reserve. At least one method for determining fractional flow reserve of the present disclosure comprises the steps positioning a device comprising at least two sensors within a luminal organ at or near a stenosis, wherein the at least two sensors are separated a predetermined distance from one another, operating the device to determine flow velocity of a second fluid introduced into me luminal organ to temporarily displace a first fluid present within the luminal organ, and determining fractional flow reserve at or near the stenosis based upon the flow velocity, a mean aortic pressure within the luminal organ, and at least one cross-sectional area at or near the stenosis. Devices and systems useful for performing such exemplary methods are also disclosed herein.07-21-2011
20100056931CARDIAC OUTPUT ESTIMATION USING PULMONARY ARTERY PRESSURE - A system and method sense a pressure signal in a pulmonary artery and compute a stroke volume and cardiac output. A pressure signal is received from an implantable pressure sensor disposed in a pulmonary artery. The pressure signal includes a systolic period and a diastolic period for determining a heart rate (HR) and a heart cycle. An iteratively-updating model can relate pressure signal and HR to a stroke volume (SV) and a cardiac output (CO). The model extracts a mean pulse pressure (MPP) from the PAP signal and receives a patient-specific vascular resistance model parameter and a patient-specific arterial compliance model parameter. CO can be calculated using the HR, the PAP signal, and the model. The vascular resistance model parameter and the arterial compliance model parameter are iteratively updated using the output of the model.03-04-2010
20110082376PHYSIOLOGICAL BLOOD PRESSURE WAVEFORM COMPRESSION IN AN ACOUSTIC CHANNEL - Methods, systems and devices for processing blood pressure measurements are disclosed. An illustrative method includes transmitting a command to an implantable medical device including a blood pressure sensor. The method includes receiving a response from the implantable medical device, the response indicating that the device initiated the sensing of blood pressure measurements. The method includes receiving one or more data packets from the implantable medical device. The one or more data packets can include a base pressure measurement that is representative of a starting point of a blood pressure waveform. The one or more data packets further include a delta value measurement representative of a difference between another blood pressure measurement and the base pressure measurement, or a difference between a current measurement and one or more previous measurements. Additionally, the method includes generating a pressure waveform from the one or more data packets.04-07-2011
20110152698METHOD AND APPARATUS FOR BLOOD PRESSURE WAVEFORM BASELINE ESTIMATION AND REMOVAL - An implantable medical device system including an implantable blood pressure sensor extracts a baseline signal from the sensed blood pressure signal and subtracts the extracted baseline signal from the sensed blood pressure signal to obtain a corrected pressure monitoring signal. The corrected pressure signal is monitored to detect a cardiac-related condition.06-23-2011
20120277601DETECTION OF HYPOVOLEMIA USING IMPLANTABLE MEDICAL DEVICE - An implantable medical device receives a physiological signal indicative of circulatory blood volume and detects hypovolemia from that physiological signal. In one embodiment, an implantable pulmonary artery pressure (PAP) senses a PAP signal, and the implantable medical device detects hypovolemia from the PAP signal.11-01-2012
20130165801PASSIVE PRESSURE SENSOR FOR IMPLANTABLE LEAD - A passive pressure sensor is used with an implantable lead to measure pressure within a patient's heart. In some embodiments, the passive pressure sensor is incorporated into an implantable lead. In other embodiments, the passive pressure sensor is incorporated into a device that is slid onto an implantable lead.06-27-2013
20100280397Method and apparatus for monitoring an organ of a patient - An apparatus for determining tissue versus fluid components of an organ include a detector that generates a detector signal based on electrical signals derived from tissue and fluid. The apparatus includes a signal processor in communication with the detector which subtracts in real time a tissue component from the detector signal and produces a fluid volume signal. A method for monitoring a patient's fluid volume of a patient's organ. An apparatus for monitoring a patient's organ. A method for monitoring a patient's organ. A method to piggyback an admittance system onto a AICD/Bi-ventricular Pacemaker for a heart of a patient, in particular a weakened heart having features consistent with congestive heart failure. An apparatus for monitoring an organ, such as a heart, lungs, brain, skeletal muscle, and bladder of a patient which includes a detector which detects the admittance of the organ. The apparatus includes a transmitter in communication with the detector which transmits a wireless signal indicative of the admittance of the organ. A method for monitoring an organ of a patient includes the steps of detecting with a detector the admittance of the organ. There is the step of transmitting with a transmitter in communication with the detector a wireless signal indicative of admittance of the organ.11-04-2010
20120203118TRANSCEIVER UNIT IN A MEASUREMENT SYSTEM - A measurement system may comprise a sensor wire and a transceiver unit. The sensor wire may comprise an insertable portion configured to be inserted in a blood vessel of a patient's body and a sensor disposed within the insertable portion at a distal end of the sensor wire. The sensor is configured to measure a parameter when inserted inside the patient. The transceiver unit may comprise: a housing adapted to be connected to a proximal end of the sensor wire; and a first communication module within the housing adapted to wirelessly communicate by a communication signal with an external second communication module in order to transfer information to the external second communication module.08-09-2012
20090221923Cardiac Disease Treatment System - Problems To provide a cardiac disease treatment system for accurately diagnosing the functional cause of an abnormality of a cardiac disease by analyzing the hemodynamic state of a patient, automatically performing medication in accordance with the diagnosis result, and treating the cardiac disease. 09-03-2009
20080243007Pulmonary Artery Pressure Signals And Methods of Using - Embodiments of the invention are related to methods and systems for using a pulmonary artery pressure signal to detect and/or monitor physiological parameters, physiological status, and aspects of disorders and diseases, amongst other things. In an embodiment, the invention includes a method for detecting pulmonary symptoms of a disorder. In an embodiment, the invention includes a method for detecting a pathological change to a tissue, structure, or fluid volume in or around the lung. In an embodiment, the invention includes a method for detecting a disorder affecting airflow. Other aspects and embodiments are provided herein.10-02-2008
20090118627SYSTEM AND METHOD FOR EVALUATING CARDIAC PERFORMANCE RELATIVE TO PERFORMANCE OF AN INTRATHORACIC PRESSURE MANEUVER - A system and method for evaluating cardiac performance relative to performance of an intrathoracic pressure maneuver is described. Blood pressure is indirectly sensed by directly collecting intracardiac impedance measures through an implantable medical device. Cardiac functional changes to the blood pressure are evaluated in response to performance of an intrathoracic pressure maneuver.05-07-2009
20080255463Method of Obtaining an Estimation of a Person's Aortic Blood Pressure - A method of obtaining an estimation of a person's aortic systolic blood pressure, which method comprises non-invasively measuring the person's brachial systolic blood pressure, non-invasively measuring the person's brachial diastolic blood pressure, obtaining the person's radial augmentation index by measuring the person's radial pulse waveform, and obtaining the estimation of the person's aortic systolic blood pressure from the following equation: aSBP=α+β·rA1x+γ·bSBP+δ·bDBP where the coefficients α, β, γ and δ are constants with approximate values of α=−24.2, β=0.28, γ=0.83, δ=0.17.10-16-2008
20100292585LIVING BODY INFORMATION DETECTION APPARATUS AND BLOOD-PRESSURE METER - A living body information detection apparatus for detecting living body information at an auricle of a human body. The living body information detection apparatus having a shape that follows a cartilage of the auricle in a periphery of a concha auriculae.11-18-2010
20110118613BLOOD PRESSURE MEASUREMENT DEVICE AND BLOOD PRESSURE MEASUREMENT METHOD - A blood pressure measurement device is characterized in that the said device is designated to arithmetically apply to the computed blood pressure value a correction value that is in accordance with the difference in atmospheric pressure between the position of the blood pressure transmitting part and the position of the heart of the subject wearing the blood pressure transmitting part as obtained from the sensor signal, on the basis of the internal pressure variation of the blood pressure transmitting part.05-19-2011
20110118612Valved Catheter with Integrated Pressure Measurement Capabilities - Valve assemblies and valved catheters including pressure sensors, and related methods for treating patients, are disclosed. The valve assembly includes a valve member extending across a first lumen and includes a planar flexible member with an internal slit acting as a valve. The valve assembly further includes a pressure sensor located distally from the valve member and in fluid communication with the first lumen.05-19-2011
20100305458BLOOD PRESSURE METER AND METHOD FOR OPERATING A BLOOD PRESSURE METER - A blood-pressure measuring device includes a resistor having a first end and a second end, a first pressure sensor disposed on the first end and a second pressure sensor disposed on the second side and configured for connection to a blood circuit, wherein the first pressure sensor, the resistor and the second pressure sensor are connected to each other in series. A computing device is connectable to the first pressure sensor and the second pressure sensor and is configured to perform a plausibility check by comparing measurement results of the first pressure sensor and of the second pressure sensor.12-02-2010
20120078124APPARATUS AND METHOD FOR SENSOR DEPLOYMENT AND FIXATION - A delivery system for fixation of an implant assembly having an intracorporeal device at a deployment site using an anchoring structure. This invention provides an implant assembly having an anchor for fixation within a vessel. The anchoring structure adapted to be delivered via a catheter.03-29-2012
20100191129Calibration of in vivo blood pressure sensors - A method for performing an in-vivo calibration of a blood pressure sensor that is associated with an in-vivo balloon system. The method involves monitoring a patient's blood pressure by observing the system gas pressure while at the same time monitoring the patient's blood pressure through the sensor. The blood pressure measurements obtained by monitoring the system gas pressure are used as reference, or “true,” blood pressure measurements, and an “offset” is determined between the reference blood pressure measurements and the blood pressure measurements obtained through the sensor. The offset can be stored in a memory, which may also store sensor sensitivity data. The offset and/or sensitivity data may be used to adjust future measurements obtained from the sensor, thereby generating calibrated sensor measurements.07-29-2010
20110190643System for Cardiac Status Determination - A system improves detection and diagnosis of blood pressure based cardiac function and tissue activities by analyzing and characterizing cardiac blood pressure signals (including non-invasive and invasive blood pressure, discrete values and continuous waveforms) using pressure signal variation and variability calculation and evaluation. The system combines blood pressure analysis with multi clinical related factors and parameters to detect and quantify cardiac health status and arrhythmia severity. The system determines an accurate time, location and severity of cardiac pathology and events by calculating blood pressure variability and statistical variation. The accurately and reliably identifies cardiac disorders, differentiates cardiac arrhythmias, characterizes pathological severity, predicts the life-threatening events, and supports evaluation of drug delivery effects.08-04-2011
20110201948IMPLANTABLE PRESSURE MONITOR - An implantable pressure monitor.08-18-2011
20090088650INTRAVASCULAR PRESSURE DEVICES INCORPORATING SENSORS MANUFACTURED USING DEEP REACTIVE ION ETCHING - An intravascular pressure sensor assembly is disclosed herein that is produced in part using photolithography and DRIE solid-state device production processes. Using DRIE production processes facilitates a number of features that could not be readily incorporated in sensor chips fabricated using mechanical saws. In accordance with a first feature, sensor chips are created with non-rectangular outlines. The sensor chip includes a widened portion that substantially abuts an inner wall of a sensor housing, and a cantilevered portion that is relatively narrow in relation to the widened portion. The non-rectangular outline of the sensor chip is formed using photolithography in combination with DRIE processing. In accordance with another feature, the sensor chip is positioned width-wise in the housing, thereby reducing a required length for the housing. In accordance with yet another feature, the sensor chip comprises one or more cutouts for receiving signal wires for connection to signal lead lines on the sensor chip. The outline of the sensor chip and the cutouts are formed using photolithography in combination with DRIE processing.04-02-2009
20110313302BLOOD PRESSURE MEASUREMENT WITH IMPLANTABLE MEDICAL DEVICE - An implantable medical device is connected to a cardiomechanic sensor implanted in or in connection with a cardiac ventricle. The sensor generates a deformation signal representative of the myocardial deformation. The implantable medical device processes the deformation signal by calculating the derivative thereof to generate a deformation rate signal representative of the rate of myocardial deformation. The deformation rate signal is filtered and respective maximum deformation rate values are identified for multiple cardiac cycles in the filtered deformation rate signal. A value representative of the systemic blood pressure is calculated based on a combination of the respective maximum deformation rate values.12-22-2011
20120046560APPARATUS AND METHOD FOR SENSOR DEPLOYMENT AND FIXATION - An implant assembly is implanted in vivo within a vascular system in the implant assembly has a diameter greater than a vessel and compliance characteristics such that, upon release, the implant assembly forms an interference fit is between the anchor structure and the vessel wall, thereby preventing further distal movement.02-23-2012
20110028851Implantable Blood Pressure Monitor - A method for monitoring blood pressure includes sensing and storing sympathetic nerve activity data of a patient via a recording lead of an implantable medical device. Changes in sympathetic nerve activity from the nerve activity data are determined. Corresponding changes in blood pressure are determined from the changes in sympathetic nerve activity. An alert signal and/or modification of therapy can be provided.02-03-2011
20120157861DEVICES AND METHOD FOR DETERMINING AND MONITORING A CARDIAC STATUS OF A PATIENT BY USING PLVDT OR PLVST PARAMETERS - The present invention relates to an improved medical device and method for accurately and reliably determining a cardiac status of a patient. An implantable medical device, IMD, comprises a sensor arrangement adapted to sense signals related to mechanical activity of the heart and an activity level sensor arrangement adapted to sense an activity level of the patient. Further, the IMD calculates a percentage of left ventricular diastolic time (PLVDT) for a cardiac cycle corresponding to a relation between a diastolic time interval and a cardiac cycle time interval using the determined systolic and diastolic time intervals or a percentage of left ventricular systolic time (PLVST) for a cardiac cycle corresponding to a relation between a systolic interval time interval and a cardiac cycle time interval. A cardiac status is determined based on the calculated PLVDT (or PLVST) and on an activity level of the patient.06-21-2012
20110066047ECCENTRIC PRESSURE CATHETER WITH GUIDEWIRE COMPATIBILITY - There is herein described a catheter for measuring a pressure in a cardiovascular system. The catheter comprises: a guiding tube adapted for insertion into the cardiovascular system. The guiding tube defines a lumen for sliding a guidewire therethrough. The catheter further comprises a tip pressure sensor eccentrically mounted relative to the guiding tube and a signal communication means extending therefrom. The tip pressure sensor is for sensing a pressure in the cardiovascular system and the signal communicating means is for transmitting a signal indicative of the pressure to a processing device in order to obtain a pressure measurement reading.03-17-2011
20110066046IMPLANTABLE FLAT BLOOD PRESSURE SENSING CUFF STRUCTURE AND IMPLANTABLE BLOOD PRESSURE MONITORING DEVICE USING THE CUFF STRUCTURE - An implantable flat blood pressure sensing cuff structure and an implantable blood pressure monitoring device use a first portion of the cuff structure that comprises a sidewall that extends from a surface and contains a pressure sensor, and a second portion of the cuff structure that is configured to overlie and be removably relative to the first portion. The first and second portions of the cuff structure are configured to provide an aperture extending transversely through the cuff structure for receiving a blood vessel therein generally sandwiched between the first portion and the second portion when the second portion is positioned on the first portion such that the pressure sensor is operative to detect vessel expansion and contraction.03-17-2011
20100094143Access Needle Pressure Sensor Device and Method of Use - A tool and method of positioning and delivering medical devices and therapeutics within the pericardial space, as well as other body part or space. A needle is inserted into the chest through a sub-xiphoid puncture, and the pressure within the needle is monitored manometrically or otherwise sensed as the needle is advanced towards the pericardial space. By reading the pressure within the needle while it is advanced, the clinician is able to know that he or she is avoiding insertion of it into organs or spaces not intended to be the target location. In addition the retractable sharp edge allows the operator to access the space and cut tissue but do so safely by retracting the sharp edge.04-15-2010
20120220883PHYSIOLOGICAL SENSOR DELIVERY DEVICE AND METHOD - An intravascular sensor delivery device for measuring a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used to measure the pressure gradient across a stenotic lesion or heart valve, such as a fractional flow reserve (FFR) across a stenotic lesion. The sensor delivery device has a distal sleeve configured to pass or slide over a standard medical guidewire. The sensor delivery device can be sized to pass over different sizes of guidewires to enable usage in coronary and peripheral arteries, for example. The sensing mechanism (sensor) can be a fiber optic pressure sensor, such as a MEMS-based FabryPerot fiber optic pressure sensor, for example, or could employ some other technology, e.g., MEMS capacitive or piezoresistive sensor.08-30-2012
20120083703IMPLANTABLE CORONARY PERFUSION MONITORING DEVICE - An implantable coronary perfusion monitoring device for in-vivo determination of a coronary perfusion index (CPI) indicative of the coronary perfusion of a heart has a time measurement unit to determine a blood pressure reflection wave measure t indicating the timely position in the heart cycle of the maximum of a reflected blood pressure wave and in a time period starting at a preset point of time in systole and ending at a local maximum of blood pressure following aortic valve closure and, a diastolic peak pressure measurement unit adapted to determine a diastolic peak blood pressure measure DPP related to diastolic aortic peak pressure and a systolic arterial pressure measurement unit adapted to determine a systolic arterial blood pressure measure SAP related to systolic arterial pressure, and a coronary perfusion index calculating unit adapted to determine said coronary perfusion index CPI as (t·DPP)/SAP.04-05-2012
20120172731RAPID EXCHANGE GUIDE UNIT - Rapid exchange guide unit comprising an elongated support member 07-05-2012
20120215117SYSTEMS AND METHODS FOR ESTIMATING CENTRAL ARTERIAL BLOOD PRESSURE OF A PATIENT - In specific embodiments, a method for estimating a patient's central arterial blood pressure (CBP) for use with an implantable system, comprises (a) using an implanted sensor at a first site to obtain a first signal indicative of changes in arterial blood volume at the first site, the first site being along one or more peripheral arterial structures of the patient, (b) using an implanted sensor at a second site to obtain a second signal indicative of changes in arterial blood volume at the second site, the second site being a distance from the first site downstream along an arterial path of the peripheral arterial structure of the patient, and (c) using implanted electrodes to obtain a signal indicative of electrical activity of the patient's heart. The method further comprises (d) determining a time t08-23-2012
20100049062SYSTEM AND METHOD FOR ACCURATE PLACEMENT OF A CATHETER TIP IN A PATIENT - A system for accurate placement of a catheter tip in a patient, the system including a catheter adapted for placement within a patient, the catheter having a tip at a distal end thereof and having a proximal end which is normally located outside of the patient, a pressure sensor adapted to sense pressure at the tip of the catheter and catheter tip placement location indicating circuitry operative in response to at least an output of the pressure sensor for indicating the location of the catheter tip in the patient.02-25-2010
20100049060IMPLANTABLE HEMODYNAMIC MONITOR AND METHODS FOR USE THEREWITH - Provided herein are implantable systems that include an implantable photoplethysmography (PPG) sensor, which can be used to obtain an arterial PPG waveform. In an embodiment, a metric of a terminal portion of an arterial PPG waveform is determined, and a metric of an initial portion of the arterial PPG waveform is determined, and a surrogate of mean arterial pressure is determined based on the metric of the terminal portion and the metric of the initial portion. In another embodiment, a surrogate of diastolic pressure is determined based on a metric of a terminal portion of an arterial PPG waveform. In a further embodiment, a surrogate of cardiac afterload is determined based on a metric of a terminal portion of an arterial PPG waveform.02-25-2010
20100298722LIVING BODY INFORMATION DETECTION APPARATUS AND BLOOD-PRESSURE METER - A living body information collecting apparatus with a part of the living body information collecting apparatus includes a shape composed of a cylinder, a cone, a prism, a pyramid, a truncated cone or a truncated pyramid. The living body information collecting apparatus further including a sensing part for collecting living body information.11-25-2010
20100298721APPARATUS AND METHOD FOR ESTIMATING BLOOD PRESSURE BY USING VARIABLE CHARACTERISTIC RATIO - A method of estimating blood pressure includes obtaining a pressure wave detected at a measurement body part of a subject, calculating a characteristic ratio of the subject according to a shape of the detected pressure wave based on a correlation between the characteristic ratio used to determine blood pressure at a measurement body part and the shape of the pressure wave detected at the measurement body part, and estimating blood pressure at the measurement body part of the subject is estimated using the calculated characteristic ratio.11-25-2010
20120190992SYSTEM AND METHOD FOR DETECTION OF PULMONARY EMBOLISM - Systems and methods provide for ambulatorily sensing pulmonary artery pressure from within a patient, and producing a pulmonary artery pressure measurement from the sensed pulmonary artery pressure. Power is ambulatorily provided within the patient to facilitate sensing of the pulmonary artery pressure and producing of the pulmonary artery pressure measurement. Acute pulmonary embolism is detected based on a change or rate of change in the pulmonary artery pressure measurement. An alert is preferably generated in response to detecting pulmonary embolism.07-26-2012
20110004109DETECTION OF HYPOVOLEMIA USING IMPLANTABLE MEDICAL DEVICE - An implantable medical device receives a physiological signal indicative of circulatory blood volume and detects hypovolemia from that physiological signal. In one embodiment, an implantable pulmonary artery pressure (PAP) senses a PAP signal, and the implantable medical device detects hypovolemia from the PAP signal.01-06-2011
20120271178PRESSURE WIRE ASSEMBLY - A pressure sensor wire assembly measures pressure inside a body of a patient. The assembly comprises a pressure sensor element for measuring pressure and to generate a pressure sensor signal representative of the pressure, and a pressure sensor wire having the pressure sensor element at its distal portion, and adapted to be inserted into the body in order to position the sensor element within the body. A sensor signal adapting circuitry is an integrated part of the assembly, wherein the pressure sensor signal is applied to the adapting circuitry which is adapted to automatically generate an output pressure signal, related to the sensor signal, in a standardized format such that the measured pressure is retrievable by an external physiology monitor. The assembly further comprises an external pressure sensor to measure the pressure outside the patient's body and to generate external pressure values in dependence thereto.10-25-2012
20110319773Multipurpose Host System for Invasive Cardiovascular Diagnostic Measurement Acquisition Including an Enhanced Dynamically Configured Graphical Display - The present invention provides a multipurpose host system for processing and displaying invasive cardiovascular diagnostic measurement data. The system includes a an external input signal bus interface. The bus interface receives data arising from cardiovascular diagnostic measurement sensors. Measurement processing components receive data from particular sensor types. Based on the received data, the processing components render diagnostic measurement parameter values. A multi-mode graphical user interface includes display components corresponding to data received from particular sensor types. The user interface provides recommended action prompts that guide a user through a series of actions.12-29-2011
20110319772LEAD MOTION SENSING VIA CABLE MICROPHONICS - An ambulatory medical device can include an excitation circuit configured to be electrically coupled to an implantable lead, the excitation circuit configured to provide a non-tissue-stimulating first signal to the implantable lead when the implantable lead is located at or near a tissue site. In an example, the system can include a detection circuit configured to be electrically coupled to the implantable lead and configured to receive a second signal, in response to the first signal, from the implantable lead, the second signal is determined at least in part by a motion of the implantable lead.12-29-2011
20120289840ESTIMATION OF PRESSURE AT REMOTE SITE BY BRACHIAL OSCILLOMETRIC WAVEFORM ANALYSIS - The present invention relates to a device and a method for estimating central systolic blood pressure based on oscillometric signals from brachial artery by the use of a pressure cuff.11-15-2012
20130012824CORONARY VENOUS SYSTEM PRESSURE SENSING - Disclose herein is a method of measuring pressures in a coronary sinus. In one embodiment, the method includes: introducing a distal portion of a lead or tool into the coronary sinus, wherein the distal portion includes first and second pressure sensors and at least one selectably expandable member; expanding the at least one expandable member such that the first and second sensors are isolated from each other within the coronary sinus; and taking pressure measurements with the first and second sensors when isolated from each other.01-10-2013
20080234588Method and Apparatus for Determining Cardiac Performance in a Patient with a Conductance Catheter - An apparatus for determining cardiac performance in the patient involving a conductance catheter (09-25-2008
20130178751IMPLANTABLE MEDICAL DEVICE FOR MEASURING PRESSURE VIA AN L-C RESONANT CIRCUIT - An implantable medical device controls the excitation of and processes signals received from passive pressure sensor components of an implantable lead. The passive pressure sensor components include an inductor-capacitor (L-C) resonant circuit that has a resonant frequency that corresponds in some aspects to the pressure external to the implantable lead. The capacitive circuit portion of the resonant circuit may be flexible such that changes in pressure at the capacitive circuit cause changes in the capacitance of the capacitive circuit. Thus, changes in pressure at the pressure sensor are reflected by changes in the resonant frequency of the excited resonant circuit. The L-C resonant circuit is excited by a signal coupled to the L-C resonant circuit by the implantable medical device. In some embodiments, the implantable medical device receives such an excitation signal from an external device. In some embodiments, the implantable medical device generates the excitation signal.07-11-2013
20130178750Methods and Apparatus for Regulating Blood Pressure - A blood pressure control apparatus, system, and methods of modifying intravascular blood flow of a patient is disclosed. In one aspect, the blood pressure control apparatus comprises an intravascular flow-modifying device including an expandable, hollow, stent-like support member configured for implantation within the vasculature, which includes an upstream sensor, a downstream sensor, and a flow restrictor. The flow restrictor is configured to partially occlude a vessel lumen and thereby artificially create back pressure upstream of the device, which causes dilation of the vessel wall and activation of the baroreceptors upstream of the device. Activation of the baroreceptors may depress the activity of the sympathetic nervous system, thereby contributing to a decrease in systemic blood pressure. The flow restrictor is also configured to partially occlude the renal vein lumen, thereby artificially increasing renal perfusion and depressing the baroreceptor-mediated sympathetic and neurohormonal efforts to raise blood pressure.07-11-2013
20080200821LEFT ATRIAL ACCESS APPARATUS AND METHODS - Left atrial access apparatus and methods are described herein. Different parameters, such as oxygen saturation difference, between the left and right atrial chambers is utilized to guide a needle or catheter into a desired position within the heart. Various sensing elements can be utilized to detect the physiological parameter difference, such as oxygen levels, in the left atrium. The sensor can be carried by the needle, at its tip or along its body, and can measure the physiological parameter levels contained in the blood, fluid, or tissue.08-21-2008
20100286537SYSTEM FOR DETERMINING THE BLOOD FLOW IN A CORONARY ARTERY - The invention relates to a method and a system for determining the blood flow in an individual coronary artery of a patient, wherein the method comprises the steps of positioning a temperature sensor mounted at a distal portion of a guide wire at a distal position in the coronary artery, positioning an infusion catheter in the coronary artery such that the distal end of the infusion catheter is proximally of the temperature sensor, measuring the blood temperature with the temperature sensor, infusing cold indicator fluid with a known infusion rate and known or measurable temperature into the coronary artery by the infusion catheter, measuring the temperature of the mixture of blood and indicator fluid by the temperature sensor, and calculating the coronary blood flow by a formula based on the known and measured quantities. In an extended version, the method comprises steps for relating the calculated coronary flow value to related normal flow values, or related FFR values, or a related flow resistance.11-11-2010
20100286536TRANSCEIVER UNIT IN A MEASUREMENT SYSTEM - A measurement system, comprises a sensor wire and a transceiver unit. The sensor wire comprises an insertable portion configured to be inserted in a blood vessel of a patient's body and a sensor disposed within the insertable portion at a distal end of the sensor wire. The sensor is configured to measure a variable inside the patient. The transceiver unit comprises: a housing adapted to be connected to a proximal end of the sensor wire; and a first communication module within the housing adapted to wirelessly communicate by a communication signal with an external second communication module in order to transfer information to the external second communication module. The communication signal, including sensor values, is generated by the transceiver unit and transferred as a data stream. The housing is configured to remain external to the patient's body.11-11-2010
20130150737MICROVASCULAR OBSTRUCTION DETECTION AND THERAPY - A method of detecting and treating a microvascular obstruction is provided. In one embodiment, a catheter is provided for both detecting the microvascular obstruction and treating or removing the obstruction.06-13-2013
20130137999SYSTEM AND METHOD FOR ESTIMATING ELECTRICAL CONDUCTION DELAYS FROM IMMITTANCE VALUES MEASURED USING AN IMPLANTABLE MEDICAL DEVICE - Techniques are provided for estimating electrical conduction delays with the heart of a patient based on measured immittance values. In one example, impedance or admittance values are measured within the heart of a patient by a pacemaker or other implantable medical device, then used by the device to estimate cardiac electrical conduction delays. A first set of predetermined conversion factors may be used to convert the measured immittance values into conduction delay values. In some examples, the device then uses the estimated conduction delay values to estimate LAP or other cardiac pressure values. A second set of predetermined conversion factors may be used to convert the estimated conduction delays into pressure values. Techniques are also described for adaptively adjusting pacing parameters based on estimated LAP.05-30-2013
20130131523INTRAVASCULAR SENSING METHOD AND SYSTEM - Methods and systems for calculating a corrected Fractional Flow Reserve. Methods include delivering a pressure sensing device including a pressure sensor to a location in an artery having a stenosis, positioning the pressure sensor distal to the stenosis, measuring the distal pressure, measuring the proximal pressure, and calculating a corrected Fractional Flow Reserve using the measured proximal and distal pressures and applying a correction factor or correction equation. The correction factor or correction equation corrects for changes in the measured distal pressure caused by a presence of the pressure sensing device. A data set of correction factors or correction equations may be stored in a memory component of the system. The corrected Fractional Flow reserve may approximate the Fractional Flow Reserve that would be obtained if a different sized device was used to measure the distal pressure, such as a pressure sensing guidewire having a 0.014 inch outer diameter.05-23-2013
20100317977IMPLANTABLE MEDICAL DEVICE WITH INTERNAL PIEZOELECTRIC ENERGY HARVESTING - Methods, systems, and apparatus for powering and/or recharging medical devices implanted within the body are described. An illustrative power generation module disposable within the interior space of an implantable medical device includes a module body that defines an interior cavity as well as a flexible diaphragm that spans the interior cavity. The flexible diaphragm includes a first electrical conductor, a piezoelectric layer disposed adjacent to the first electrical conductor, and a second electrical conductor disposed adjacent to the piezoelectric layer. The piezoelectric layer is configured to displace within the interior cavity and generate a voltage differential between the first electrical conductor and the second electrical conductor.12-16-2010
20130190633Interface Devices, Systems, and Methods for Use With Intravascular Pressure Monitoring Devices - Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to provide FFR measurements in a small, compact device that integrates with existing proximal and distal pressure measurement systems and does not require a separate power source.07-25-2013
20130204147Atrial Fibrillation Detection Based On Pulmonary Artery Pressure Data - Atrial fibrillation (AF) is detected based on pulmonary artery pressure (PAP) data. In some embodiments, PAP data generated by a PAP sensor device implanted in or near the pulmonary artery of a patient is processed to determine whether the patient is suffering from AF. In some aspects, detection of AF is based on identifying cycle-to-cycle variations of one or more parameters derived from the PAP data.08-08-2013

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