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Measuring pressure in heart or blood vessel

Subclass of:

600 - Surgery

600300000 - DIAGNOSTIC TESTING

600481000 - Cardiovascular

Patent class list (only not empty are listed)

Deeper subclasses:

Class / Patent application numberDescriptionNumber of patent applications / Date published
600490000 Force applied against skin to close blood vessel 284
600486000 Testing means inserted in body 121
600489000 Ophthalmodynamometer 1
20110071408METHOD FOR DETECTING VASCULAR SCLEROSIS - A method for detecting vascular sclerosis is revealed. Firstly set a cuff on a human hand. Then inflate the cuff and later deflate the cuff. Next measure a pressure of the cuff and generate a pressure sensing signal. Process the pressure sensing signal to generate a processed signal and convert the processed signal. Then calculate a systolic pressure and a diastolic pressure according to the converted processed signal and also obtain a vasodilation constant. Thus a hardening of blood vessels is detected according to the vasodilation constant.03-24-2011
Entries
DocumentTitleDate
20100160793BIOSIGNAL MEASUREMENT MODULES AND METHODS - A biosignal measurement module is provided and includes a biosignal measurement unit, a pose detection unit, and a processing unit. The biosignal measurement unit measures an electrocardiogram signal and a pulse signal of a subject. The pose detection unit detects a position of the biosignal measurement module and outputs position signals. The processing unit receives the electrocardiogram signal, the pulse signal, and the position signals. The processing unit generates a height variation parameter, which indicates the height difference between the position of the biosignal measurement module and a reference position, according to the position signals. The processing unit calculates a current pulse transit time according to the electrocardiogram signal and the pulse signal and compensates for the current pulse transit time according to the height variation parameter to obtain a compensated pulse transit time. The processing unit obtains a blood pressure signal according to the compensated pulse transit time.06-24-2010
20090062665NONINVASIVE METHOD AND APPARATUS FOR MEASURING BLOOD PRESSURE BY DETERMINING A MAXIMUM FREQUENCY OF SPECTRAL CONTENT OF THE SECOND HEART SOUND - Methods and apparatus for noninvasively estimating a blood pressure are provided. A bandpass filter is applied to a second heart sound (S2) component to generate a filtered S2 component. The bandpass filter has a lower cutoff frequency greater than a maximum frequency of the S2 component. The maximum frequency of the S2 component is estimated using the filtered S2 component, a predetermined relationship is applied between the estimated maximum frequency and blood pressure to generate a blood pressure estimate and the blood pressure estimate is displayed.03-05-2009
20110196244SYSTEM AND APPARATUS FOR THE NON-INVASIVE MEASUREMENT OF BLOOD PRESSURE - The present invention relates to a system for the estimation of the systolic (SBP), diastolic (DBP) and average (MAP) blood pressure. Said system establishes a physiological model of the pulse wave combined with its energy for, afterwards, generating a fixed length vector containing the previous model's values with other variables related to the user like, for example, age, sex, height, weight, etc. . . . This fixed length vector is used as an input of a function estimator system based on “random forests” for the calculation of the three variables of interest. The main advantage of this function estimator lies in that it does not impose any restriction beforehand over the function to be estimated, and it is also very reliable with heterogeneous data, as in the present invention's case.08-11-2011
20110295128BLOOD-PRESSURE SENSOR - A blood-pressure sensor includes a substrate, a first electrode, a magnetization fixed layer, a nonmagnetic layer, a magnetization free layer, and a second electrode. The substrate is bent to generate a tensile stress at least in a first direction. The first electrode is provided on the substrate. The magnetization fixed layer has magnetization to be fixed in a second direction, and is provided on the substrate. The nonmagnetic layer is provided on the magnetization fixed layer. The magnetization free layer has a magnetization direction which is different from the first direction and from a direction perpendicular to the first direction. The second electrode is provided on the magnetization free layer.12-01-2011
20120179052Biodegradable Fluid Delivery Device - An assembly for a fluid transfer system includes: a connector having a proximal end and an opposite distal end connected by an inner passage; and a container having an internal fluid reservoir. The connector is coupled to the internal fluid reservoir of the container to form a series fluid connection between the inner passage and the internal fluid reservoir, and the connector and the container are made of a biodegradable material.07-12-2012
20100076326METHOD FOR ESTIMATING CHANGES OF CARDIOVASCULAR INDICES USING PERIPHEAL ARTERIAL BLOOD PRESSURE WAVEFORM - The systems and methods described herein enable reliable estimation of cardiovascular indices on real-time, non-invasive or minimally-invasive, and beat-to-beat basis. Cardiovascular indices which can be estimated include), stroke volume (SV), without being limited to, cardiac output (CO and total peripheral resistance (TPR). In various embodiments, one or more of these indices are estimated continuously, on a beat-to-beat basis, using peripheral arterial blood pressure (ABP) waveforms and certain parameters derived from the peripheral ABP waveforms. The derived parameters are substantially insensitive to distortions of the ABP waveform arising from tapered arterial branches throughout the arterial tree. The methods described herein can provide a more accurate and reliable estimate of hemodynamic parameters than existing techniques.03-25-2010
20100094140Noninvasive Method and Apparatus to Measure Body Pressure Using Extrinsic Perturbation - Current noninvasive blood pressure measurement methods are not able to measure pressure during nonpulsatile blood flow. We propose method to measure intravascular or other compartment pressure which applies extrinsic pressure oscillation. Pressure-volume response of the compressed structure is obtained and compartment pressure is estimated as the extrinsic pressure at which compressed structure has the highest compliance. Delivering extrinsic oscillations at a higher frequency than the pulse rate, pressure reading can be obtained much faster. Because it is not dependant on intrinsic vascular oscillations, pressure can be measured during arrhythmias, during cardiac bypass, during resuscitation, in the venous compartment or in the other nonpulsatile compressible body compartments.04-15-2010
20100160794BODY-WORN SYSTEM FOR MEASURING CONTINUOUS NON-INVASIVE BLOOD PRESSURE (cNIBP) - The present invention provides a technique for continuous measurement of blood pressure based on pulse transit time and which does not require any external calibration. This technique, referred to herein as the ‘Composite Method’, is carried out with a body-worn monitor that measures blood pressure and other vital signs, and wirelessly transmits them to a remote monitor. A network of body-worn sensors, typically placed on the patient's right arm and chest, connect to the body-worn monitor and measure time-dependent ECG, PPG, accelerometer, and pressure waveforms. The disposable sensors can include a cuff that features an inflatable bladder coupled to a pressure sensor, three or more electrical sensors (e.g. electrodes), three or more accelerometers, a temperature sensor, and an optical sensor (e.g., a light source and photodiode) attached to the patient's thumb.06-24-2010
20080208064Method and apparatus for measuring blood pressure - A method and an apparatus for measuring blood pressure are disclosed. The method is applied to a blood pressure measurement apparatus and comprises the steps of providing a sensing unit for sensing a user's pulse, counting the pulse in a time interval by a counting unit based on the sensing unit to calculate a pulse rate, determining the condition of the pulse rate by a determination mechanism to generate an operation signal, controlling the blood pressure measurement apparatus based on the operation signal to determine whether or not the pulse rate is steady to ensure the accuracy of measuring the blood pressure. Therefore, the invention can improve the inaccuracy of the blood pressure measurement caused by human errors.08-28-2008
20130041270BLOOD PRESSURE MEASURING DEVICE AND SYSTEM WITH AUTOMATIC SELF-EXAMINATION AND SELF-CALIBRATION FUNCTIONS - A blood pressure measuring system with automatic self-examination and self-calibration functions, which utilizes an examining and calibrating unit to automatically compare pressure information detected by a signal detection unit with an original factory calibration value for pressure, to self-calibrate the blood pressure measuring system, wherein the examining and calibrating unit can be arranged in a blood pressure measuring device or in an external electronic device, for providing users a method to confirm accuracy of the blood pressure measuring system to prevent serious consequence caused by miscalculations of blood pressure and physiological values. Accordingly, original factory calibration can be skipped to save time and money; calibration and examination processes are simplified and more convenient.02-14-2013
20090124910Method for processing of continuous pressure-related signals derivable from a human or animal body or body-cavity - This invention describes a method for processing pressure signals derivable from locations inside or outside a human or animal body or body cavity. Different aspects of the invention relate to a method for optimal differentiating between cardiac beat- and artifact-induced pressure waves, a method for obtaining new and improved information from said pressure signals, a method for obtaining signals predicting pressures inside a body or body cavity from pressure signals outside said body or body cavity. In particular, this invention describes a method for modifying individual continuous non-invasive pressure-related signals into signals highly predictable of the corresponding invasive pressure-related signals based on already established relationships that can be used for formula-based adjustments of individual signals solely obtained by a non-invasive approach.05-14-2009
20090306524SENSOR FOR DETECTING THE PASSING OF A PULSE WAVE FROM A SUBJECT'S ARTERIAL SYSTEM - In order to provide an easy-to-use technique for measuring blood pressure and/or other vital signs of a subject, a sensor for detecting the passing of a pulse wave from a subject's arterial system is suggested, the sensor being adapted to be located at a sensing position on the exterior of the subject's body, characterized in that the sensor comprises a number of electrical coils for generating an inductive coupling to the subject's body in a way that the properties of said inductive coupling change if a pulse wave passes a screened volume underneath the sensing position, and a circuit connected to the number of electrical coils, said circuit being adapted to detect said property changes of the inductive coupling.12-10-2009
20130072807HEALTH MONITORING APPLIANCE - A monitoring system for a person includes one or more wireless nodes; and a wearable patch or bandage appliance secured to the person' skin and in communication with the one or more wireless nodes, wherein the patch or bandage appliance monitors and transmits patient vital signs to the wireless nodes.03-21-2013
20130072806System for Cardiac Arrhythmia Detection and Characterization - A system for heart performance characterization and abnormality detection comprises an input processor and at least one signal processor. The input processor receives, sampled data representing a patient blood pressure signal and a concurrently acquired electrocardiogram (ECG) signal representing heart electrical activity of the patient. The at least one signal processor, synchronizes the patient blood pressure signal and the heart electrical activity signal, identifies at least two points of a heart electrical activity signal cycle, integrates signal data values representing the amplitude of the patient blood pressure signal of a segment between the identified two points to derive an integral value over time duration of the segment representing an area under the blood pressure signal waveform between the identified two points and in response to the derived integral value, initiates generation of a message associated with a medical condition of the patient.03-21-2013
20090270739REAL-TIME DETECTION OF VASCULAR CONDITIONS OF A SUBJECT USING ARTERIAL PRESSURE WAVEFORM ANALYSIS - Methods for the detection of vascular conditions such as vasodilation in a subject are described. The methods involve receiving a signal corresponding to an arterial blood pressure and calculating one or more cardiovascular parameters from the arterial blood pressure. The cardiovascular parameters are calculated using factors impacted by vascular conditions such as vasodilation. Factors impacted by these vascular conditions include the area under the systolic portion of the arterial blood pressure signal, the duration of systole, and the ratio of the duration of the systole to the duration of the diastole. By monitoring cardiovascular parameters that are calculated using factors impacted by vascular conditions such as vasodilation for changes indicating the vascular conditions, such vascular conditions can be detected.10-29-2009
20100081946METHOD AND APPARATUS FOR NON-INVASIVE CUFF-LESS BLOOD PRESSURE ESTIMATION USING PULSE ARRIVAL TIME AND HEART RATE WITH ADAPTIVE CALIBRATION - Certain aspects of the present disclosure relate to a method for estimating a blood pressure using both a pulse arrival time (PAT) and an instantaneous heart rate (HR). The PAT can be measured as the delay between QRS peaks in an electrocardiogram (ECG) signal and corresponding points in a photoplethysmogram (PPG) waveform. Parameters of the estimation model can be determined through an initial training. Then, the model parameters can be recalibrated in constant intervals using the recursive least square (RLS) approach combined with a smooth bias fixing. The proposed estimation algorithm is applied on a multi-parameter intelligent monitoring for intensive care (MIMIC) database, and the results are compared with estimation methods that use PAT only or HR only. The proposed estimation algorithm meets, on average, the Association for the Advancement of Medical Instrumentation (AAMI) requirements and outperforms other methods from the prior art. It is also shown in the present disclosure that the proposed estimation algorithm is robust to unknown skew between the ECG and PPG signals.04-01-2010
20100081945Systems and Methods for Maintaining Blood Pressure Monitor Calibration - Systems and methods are disclosed herein for maintaining the calibration of non-invasive blood pressure monitoring devices. Phase components of pulse signals detected by the blood pressure monitoring device are compared to stored baseline phase component values. If the difference exceeds a threshold, the blood pressure monitoring device is recalibrated.04-01-2010
20100081944Systems and Methods for Recalibrating a Non-Invasive Blood Pressure Monitor - Techniques for non-invasive blood pressure monitoring are disclosed. Data corresponding to a patient may be received from a hospital information system. The data may include, for example, drug administration data, medical procedure data, medical equipment data, or a combination thereof. Whether a blood pressure monitoring system needs to be recalibrated may be determined, based at least in part on the received data. If it is determined that the blood pressure monitoring system needs to be recalibrated, the recalibration may be performed and at least one blood pressure measurement of the patient may be computed using the recalibrated blood pressure monitoring system.04-01-2010
20110021929SYSTEMS AND METHODS FOR CONTINUOUS NON-INVASIVE BLOOD PRESSURE MONITORING - Systems and methods are disclosed herein for continuous non-invasive blood pressure (CNIBP) monitoring. Multiple reference blood pressure values may be obtained using a calibration device. These multiple reference blood pressure values may be used as calibration points for determining a relationship between the blood pressure of a patient and photoplethysmograph (PPG) signals.01-27-2011
20120116235SYSTEMS AND METHODS FOR PRODUCING AUDIBLE INDICATORS THAT ARE REPRESENTATIVE OF MEASURED BLOOD PRESSURE - Systems and methods are disclosed for producing audible indicators that are based on a subject's measured blood pressure. Audible properties of the indicators are processed to represent blood pressure. For example, the duration or volume of the audible indicators may be varied based on the values of the subject's blood pressure. The audible indicators may further be varied based on the subject's blood pressure's deviation from a normal blood pressure and/or previously calculated blood pressure. For example, the audible indicators may be indicative of changes in the subject's blood pressure over time. The audible indicators representing blood pressure may be synchronized with other audible indicators that represent other physiological parameters of the subject, such as, the subject's heart rate.05-10-2012
20090012409Determining Blood Pressure - A method and a measuring device for determining blood pressure, pressure signals being detected using a pressure sensor which may be applied to a body part, such as a wrist. The blood pressure is determined by an analysis unit, analyzing the pressure signals and considering signals from an orientation detection unit detecting the position and/or movement and/or acceleration of the body part.01-08-2009
20100087743Pulse Contour Method and Apparatus for Continuous Assessment of a Cardiovascular Parameter - A cardiovascular parameter such as cardiac output is estimated from a current pressure waveform data set without needing to directly measure blood flow or arterial compliance. The general shape of an input flow waveform over one beat-to-beat cycle is assumed (or computed), and then the parameters of a flow-to-pressure model, if not pre-determined, are determined using system identification techniques. In one embodiment, the parameters thus determined are used to estimate a current peripheral resistance, which is used not only to compute an estimate of the cardiovascular parameter, but also to adjust the shape of the input flow waveform assumed during at least one subsequent beat-to-beat cycle. Another embodiment does not require computation of the peripheral resistance and still another embodiment computes a flow estimate from an optimized identification of the parameters defining the assumed input flow waveform.04-08-2010
20090062666Arterial pressure-based, automatic determination of a cardiovascular parameter - One or more cardiovascular parameters is estimated as a function of the arterial pressure waveform, in particular, using at least one statistical moment of a discrete representation pressure waveform having an order greater than one. Arterial compliance, the exponential pressure decay constant, vascular resistance, cardiac output, and stroke volume are examples of cardiovascular parameters that can be estimated using various aspects of the invention. In one embodiment of the invention, not only are the first four moments (mean, standard deviation, skewness, and kurtosis) of the pressure waveform used to estimate the cardiovascular parameter(s) of interest, but also heart rate, statistical moments of a set of pressure-weighted time values, and certain anthropometric patient measurements such as age, sex, body surface area, etc.03-05-2009
20090062663NON-INVASIVE BLOOD PRESSURE MONITOR APPARATUS AND SYSTEM - A non-invasive blood pressure monitoring system is disclosed herein. The non-invasive blood pressure monitoring system includes a pressure cuff comprising a resistive portion and a conductive portion aligned with the resistive portion. The non-invasive blood pressure monitoring system also includes a controller operatively connected to the pressure cuff. The controller is adapted to estimate the circumference of the pressure cuff based on the position of the conductive portion relative to the resistive portion.03-05-2009
20090192392Method, system, and apparatus for statistical evaluation of antihypertensive treatment - A novel method, system, and apparatus—the RDH Method—for evaluating antihypertensive treatment efficacy across patient populations is disclosed. In accordance to one embodiment, the RDH is a population vector index and graphical method that provides the means for the statistical assessment of antihypertensive treatment reduction, duration, and homogeneity using ambulatory blood pressure monitoring (ABPM). The population RDH was specifically designed as a tool to evaluate and compare blood pressure (BP) coverage offered by antihypertensive drugs over 24 h in populations. In accordance to one embodiment, the population RDH is a three-component vector index that incorporates information about the reduction, duration, and homogeneity of antihypertensive treatment, as well as their statistical significance over the 24 h period. In the preferred embodiment, the population RDH components quantify: 1) the total number of statistical significant BP reductions, 2) the maximum number of consecutive statistical significant reductions, and 3) the maximum number of consecutive non-significant reductions over the 24 hours, respectively; and reports two population graphs that characterize the effect of the treatment. The output of the RDH index can be used in clinical trials to characterize the effects of antihypertensive medications, and in clinical practice to guide antihypertensive treatment.07-30-2009
20080319327BODY-WORN SENSOR FEATURING A LOW-POWER PROCESSOR AND MULTI-SENSOR ARRAY FOR MEASURING BLOOD PRESSURE - A system is described that continuously measures a patient's blood pressure over a length of time. The system features a sensor assembly featuring a flexible cable configured to wrap around a portion of a patient's arm. The flexible cable features a back surface that includes at least two electrodes that are positioned to contact the patient's skin to generate electrical signals. It additionally features an optical sensor that includes at least one light source and at least one photodetector. These components form an optical sensor that is configured to generate an optical signal by detecting optical radiation emitted by the at least one light source and reflected from a blood vessel underneath the patient's skin.12-25-2008
20100030086MONITORING HEMODYNAMIC STATUS BASED ON INTRACARDIAC OR VASCULAR IMPEDANCE - This disclosure relates to monitoring intracardiac or vascular impedance to determine a change in hemodynamic status by detecting changes in an impedance parameter over cardiac cycles. An example method includes measuring a plurality of impedance values of a path within a patient over time, wherein the path includes at least one blood vessel or cardiac chamber of the patient, and wherein the impedance values vary as a function of blood pressure within the at least one vessel or chamber, determining a plurality of values of an impedance parameter over time based on the measured impedance values, wherein each of the impedance parameter values is determined based on a respective sub-plurality of the impedance values, comparing at least one of the impedance parameter values to at least one prior impedance parameter value, and identifying a change in a cardiovascular parameter related to the blood pressure based on the comparison.02-04-2010
20110301472METHOD AND APPARATUS FOR DETERMINING AND/OR MONITORING A PHYSICAL CONDITION OF A PATIENT BASED ON AN AMPLITUDE OF A PRESSURE SIGNAL - A method for determining and/or monitoring quantities, in particular cardiovascular quantities, relating to a patient's condition, and an apparatus for measuring an amplitude of a cardiac pressure signal are disclosed. The amplitude of the pressure signal may be detected with the aid of a pressure sensor of a blood treatment apparatus, and its magnitude may be corrected by the contribution of the blood pump of the blood treatment apparatus so as to determine the amplitude of the cardiac pressure signal of the patient. The value of the amplitude of the pressure signal thus determined may subsequently be evaluated.12-08-2011
20110288421BLOOD PRESSURE MONITOR - The invention provides a method for measuring a blood pressure value of a user featuring the following steps: 1) generating optical, electrical, and acoustic waveforms with, respectively, optical, electrical, and acoustic sensors attached to a single substrate that contacts a user; 2) determining at least one parameter by analyzing the optical and acoustic waveforms; and 3) processing the parameter to determine the blood pressure value for the user.11-24-2011
20110288419ARTERIAL PULSE DECOMPOSITION ANALYSIS FOR VITAL SIGNS DETERMINATION - determining physiological life signs, with a sensor that is in contact with the surface of a patient's skin at point proximate an artery, and measuring arterial blood vessel displacement and/or blood pressure changes. A data stream of measurements of is collected and a set of parameters from the collected data, a number of physiological life signs parameters, is extracted from the data. The physiological life signs that can be extracted include heart rate, breathing rate, systolic blood pressure, and diastolic blood pressure.11-24-2011
20110288420BLOOD PRESSURE MEASURING DEVICE AND BLOOD PRESSURE MEASURING METHOD - A blood pressure measuring device includes a blood flow velocity sensor detecting a blood flow within the body; a blood flow velocity sensor driver driving the blood flow velocity sensor part; a blood flow velocity sensor signal calculating part controlling the blood flow velocity sensor driver and the blood flow velocity sensor, and obtaining the blood flow velocity within the body; a vascular diameter sensor detecting a difference in reflection arrival time for the vascular wall in the body; a vascular diameter sensor driver driving the vascular diameter sensor; a vascular diameter sensor signal calculating part controlling the vascular diameter sensor driver and the vascular diameter sensor, and obtaining the vascular diameter in the body; and a blood pressure signal calculater using a result of a calculation by the blood flow velocity sensor signal calculater and the vascular diameter sensor signal calculater to obtain the blood pressure of the subject.11-24-2011
20100249612Flow Estimation - Method and apparatus are provided for computing signals related to cardiac output from physiologic input signals related to circulatory pressures or flows. Method and apparatus are provided for constructing a transforming filter and applying said filter to the physiologic input signals in order to obtain a signal proportional to phasic cardiac output or time-averaged cardiac output. This invention provides a means for real-time monitoring of cardiac output and stroke volume which is of great clinical importance but not otherwise feasible by present techniques.09-30-2010
20110077531SYSTEMS AND METHODS FOR HIGH-PASS FILTERING A PHOTOPLETHYSMOGRAPH SIGNAL - According to embodiments, systems and methods for high-pass filtering a plethysmograph or photoplethysmograph (PPG) signal are disclosed. A sensor or probe may be used to obtain a plethysmograph or PPG signal from a subject. The sensor may be placed at any suitable location on the body, e.g., the forehead, finger, or toe. The PPG signal generated by the sensor may be high-pass filtered to disambiguate certain features of the PPG signal, including one or more characteristic points. The cut-off frequency for the high-pass filter may be greater than 0.75 Hz and less than 15 Hz. The cut-off frequency for the high-pass filter may be selected to be greater than the subject's computed pulse rate. These characteristic points on the filtered PPG signal may be used to compute non-invasive blood pressure measurements continuously or on a periodic basis. For example, the time difference between two or more characteristic points in a high-pass filtered version of the generated PPG signal may be computed. The time difference may be used to compute non-invasive blood pressure measurements continuously or on a periodic basis.03-31-2011
20090099463SYSTEM AND METHOD FOR A NON-SUPINE EXTREMITY BLOOD PRESSURE RATIO EXAMINATION - The present invention provides apparatuses and methods that facilitate the determination of a hydrostatic correction factor usable in an EBPR examination of a patient in a non-supine position. In one embodiment, a first blood pressure measuring device may be positionable on a first extremity of the patient, and a second blood pressure measuring device may be positionable on a second extremity of the patient, with one of the blood pressure measuring devices being located above the other one. The apparatus includes a locating mechanism that fixes a position of at least one of the first and second blood pressure measuring devices relative to its respective patient extremity. The apparatus also includes an instrumentality that provides information about a vertical distance between the first and second blood pressure measuring devices. The vertical distance is usable in determining the hydrostatic correction factor.04-16-2009
20090062664BLOOD PRESSURE MEASUREMENT DEVICE - A blood pressure measurement device. The device comprises a measurement component for measuring blood pressure and a display component for displaying the blood pressure data measured. The display component is adapted to display simultaneously at least two sets of blood pressure measurement data measured at different date or time. Alternatively, the device further comprises a measurement state control component for recording and storing at least one measurement state related to the measurement of the blood pressure, and means for providing the at least one measurement state. Alternatively, the device further comprises an interfacing component that comprises a bi-direction multifunctional port, for exchanging blood pressure data measured between the blood pressure measurement device and at least one external device.03-05-2009
20110263989METHODS AND APPARATUS FOR DETERMINING A CENTRAL AORTIC PRESSURE WAVEFORM FROM A PERIPHERAL ARTERY PRESSURE WAVEFORM - A method is provided for determining a central aortic pressure (AP) wave-form for a subject. The method includes measuring a peripheral artery pressure (PAP) waveform from the subject, employing a distributed model to define a pressure-to-pressure transfer function relating PAP to AP and a pressure-to-flow transfer function relating PAP to a central arterial flow in terms of the same unknown parameters, estimating the unknown parameters by finding the pressure-to-flow transfer function, which when applied to the measured PAP waveform, minimizes the magnitude of the central arterial flow waveform during diastole, and applying the pressure-to-pressure transfer function with the estimated parameters to determine an AP waveform for the subject.10-27-2011
20100268097Monitoring Peripheral Decoupling - Methods for monitoring central-to-peripheral arterial pressure decoupling, i.e., hyperdynamic conditions, are described. These methods involve the comparison of parameters calculated from multivariate statistical models established for both subjects experiencing normal hemodynamic conditions and subjects experiencing hyperdynamic conditions, in which central- to peripheral decoupling may occur. The difference or ratio between the parameters calculated using the two multivariate statistical models provides a continual indication of the level of decoupling as well as indicating peripheral decoupling when a threshold value is exceeded. These methods can be used to both alert a user to the fact that a subject is experiencing peripheral decoupling and provide accurate arterial tone measurements, which enable the calculation of accurate values for other parameters, such as stroke volume and cardiac output.10-21-2010
20090149762Apparatus for displaying the blood pressure value and method thereof - An apparatus for displaying the blood pressure and a method thereof are disclosed. The apparatus uses a blood-measuring unit for receiving an analog blood pressure signal; a photoplethysmography (PPG) signal measuring unit for receiving an analog PPG signal; an analog-to-digital converter for converting the analog blood pressure signal into a digital blood pressure signal and the analog PPG signal into a digital PPG signal; an input unit for generating a human data; a microprocessor unit for receiving the digital blood pressure signal, the digital PPG signal and the human data so as to generate a different value in response to the digital blood pressure signal and the digital PPG signal, and output a pulse wave velocity (PWV) signal in response to the operation of the different value and the human data; an LCD driving unit for outputting an first LCD driving voltage and a second LCD driving voltage respectively in response to the digital blood pressure signal and the pulse wave velocity (PWV) signal; an LCD unit for displaying the colors that correspond to the first LCD driving and the second LCD driving voltage respectively.06-11-2009
20100305457METHOD AND APPARATUS FOR ESTIMATING BLOOD PRESSURE - A method for estimating blood pressure includes sensing a sphygmus wave at a body part of a user to which vibration is applied to generate a sensed sphygmus wave, filtering the sensed sphygmus wave to generated a filtered sphygmus wave, and estimating blood pressure of the user based on time differences between peaks of the sensed sphygmus wave and peaks of the filtered sphygmus wave.12-02-2010
20120108985CUFFLESS BLOOD PRESSURE MONITOR - A cuffless blood pressure monitor is revealed. The cuffless blood pressure monitor includes a pressure detection module, a signal processing module and a display module. The pressure detection module detects blood pressure to generate a blood pressure pulse signal. The signal processing module processes the blood pressure pulse signal to generate a measurement result that is displayed by the display module. The cuffless blood pressure monitor measures continuous blood pressure pulse signals, processes the blood pressure pulse signals by the signal processing module, and calculates the measurement result for real-time measurement of blood pressure. A measurement point on the user is pressed by a soft pressure-transferring medium so that the user won't feel uncomfortable. Moreover, the cuffless blood pressure monitor is compact and portable.05-03-2012
20120108984INTEGRATED PATIENT CARE - A therapy regimen, e.g., a contingent medication prescription, may be created and automatically distributed to a patient via an integrated patient care system. A clinician may create therapy instructions by at least associating patient conditions with one or more therapy regimens, e.g., medication prescriptions. In some examples, the integrated patient care system may present historical condition data to the clinician to aid the clinician with creating and/or updating the therapy instructions specific to the patient. A therapy module of the integrated patient care system may use the therapy instructions to automatically select a therapy regimen from the therapy instructions based on a patient condition detected based on a sensed physiological parameter. The physiological parameter of the patient may be sensed by an implanted or external sensor. In some examples, the therapy regimen can be presented to the patient according to a predetermined schedule or in response to the detected condition.05-03-2012
20100125212METHOD AND APPARATUS FOR TESTING ACCURACY OF BLOOD PRESSURE MONITORING APPARATUS - A method for testing accuracy of blood pressure measurement in a blood pressure monitoring apparatus includes calculating a difference between measured blood pressures of a user measured at two or more measurement points, calculating a difference between hydrostatic pressures of blood estimated at the two or more measurement points, and calculating an error of the measured blood pressures.05-20-2010
20100125211ASSESSMENT OF PULMONARY VASCULAR RESISTANCE VIA PULMONARY ARTERY PRESSURE - Methods and systems for assessing pulmonary or systemic vascular resistance in a patient using pressure measurements are disclosed. An illustrative method of measuring pulmonary vascular resistance includes electrically inducing a retrograde pressure pulse within the heart, sensing at least one arterial pressure parameter in response to the retrograde pressure pulse using a pressure sensor located within a pulmonary artery, and computing a value of the pulmonary vascular resistance using the at least one sensed arterial pressure parameter. Data from multiple pulmonary vascular resistance assessments can be taken over an extended period of time within the patient to aid in detecting an underlying cardiac or pulmonary condition such as cardiogenic pulmonary edema.05-20-2010
20090043213LOAD INDEPENDENT INDEX OF DIASTOLIC FUNCTION - Methods and related apparatus and systems for determining a load-independent index of diastolic function in the heart are described.02-12-2009
20090281434PERSONALIZED FLUID ASSESSMENT - A system and method of monitoring the fluid status of a patient. The system may include a patient monitor that receives blood pressure data. A first fluid model receives the blood pressure data, and a personalized fluid model is derived from the application of the blood pressure data to the first fluid model. An estimation of the patient's fluid status may be derived from the personalized fluid model. The method may include the steps of measuring a first blood pressure value, creating a personalized fluid model, measuring a second blood pressure value, applying the second blood pressure value to the personalized fluid model; and deriving an estimation of the fluid status of the patient.11-12-2009
20090287095Method for Determining Cardiac Output - In a method for determining cardiac output from an arterial blood pressure curve measured at the periphery, in which the blood pressure curve measured at the periphery is arithmetically transformed into the corresponding central blood pressure curve and the cardiac output is calculated from the central blood pressure curve, the transformation of the blood pressure curve measured at the periphery into the corresponding central blood pressure curve is performed by the aid of an artificial neural network whose weighting values are determined by learning.11-19-2009
20090299197Remote Blood Pressure Waveform Sensing Method and Apparatus - The invention as disclosed is a non-contact method and apparatus for continuously monitoring a physiological event in a human or animal, such as blood pressure, which involves utilizing a laser-based interferometer system in combination with a laser tracking system and a signal processor to produce a waveform that is representative of a continuous physiological event such as blood pressure or respiration in a subject.12-03-2009
20110201947OXIDIZED PARAOXONASE 1 AND PARAOXONASE 1/HDL PARTICLE NUMBER RATIO AS RISK MARKERS FOR CARDIOVASCULAR DISEASE - The present invention provides methods and markers for characterizing a subject's, particularly a human subject risk of having cardiovascular disease. The present invention also provides methods of characterizing a subject's risk of developing cardiovascular disease. In another embodiment, the present invention provides methods for characterizing a subject's risk of experiencing a complication of cardiovascular disease or major adverse cardiac event within 1, 3, or 10 years. In another embodiment, the present invention provides a method for determining whether a subject presenting with chest pain is at risk near term of experiencing a heart attack or other major adverse cardiac event. The present methods are especially useful for identifying those subjects who are in need of highly aggressive CVD therapies as well as those subjects who require no therapies targeted at inhibiting or preventing CVD or complications of CVD.08-18-2011
20110208066NONINVASIVE BLOOD PRESSURE MEASUREMENT AND MONITORING DEVICE - Measurement of blood pressure is one of the most common procedures done in a clinical and an ambulatory environment. It is usually done with a sphygmomanometer, where an inflatable cuff is attached to the arm of a patient and the systolic and diastolic pressures are determined, typically by listening to the Korotkoff sounds. Although this method is over 100 years old and widely used, it is well known that it has severe shortcomings.08-25-2011
20130218031METHOD AND APPARATUS FOR ESTIMATING A PULSE ARRIVAL TIME VALUE - Method and apparatus for estimating an arrival time (PAT) value of a subject in an automatic and unsupervised fashion from a sequence of electrical impedance tomography (EIT) images. The method comprises: providing an EIT imaging device adapted to record impedance signal distribution within a measurement region of the subject; measuring a sequence of temporally discrete EIT images during a predetermined measuring time period in the measurement region using the EIT imaging device, each EIT image comprising one or a plurality of EIT pixel subsets, each of said one or a plurality of EIT pixel subset representing an impedance value; generating one or a plurality of time series, each of said one or a plurality of time series representing a variation of the impedance value of the sequence of EIT images; and estimating the PAT value from each of said one or a plurality of time series.08-22-2013
20100217134METHOD, A SYSTEM AND A COMPUTER PROGRAM PRODUCT FOR DETERMINING A BEAT-TO BEAT STROKE VOLUME AND/OR A CARDIAC OUTPUT - The invention relates to a method 08-26-2010
20080287811Method for Assessing The Functional Condition Of Cardiovascular System - The invention relates to medicine, namely: to cardiology, and may be used for assessment of functional condition of the human cardiovascular system (CVS) and the character of its control by the autonomic nervous system and other regulatory systems of the homeostasis. A method of non-invasive examination of the human CVS was developed, the method enabling to continuously, during a necessary period of time and quite simply with the aid of a computer and a piezoceramic tranducer (FIG. 11-20-2008
20080287812Systems and Methods for Model-Based Estimation of Cardiac Output and Total Peripheral Resistance - The methods and systems for estimating cardiac output and total peripheral resistance include observing arterial blood pressure waveforms to determine intra-beat and inter-beat variability in arterial blood pressure and estimating from the variability a time constant for a lumped parameter beat-to-beat averaged Windkessel model of the arterial tree. Uncalibrated cardiac output and uncalibrated total peripheral resistance may then be calculated from the time constant. Calibrated cardiac output and calibrated total peripheral resistance may be computed using calibration data, assuming an arterial compliance that is either constant or dependent on mean arterial blood pressure. The parameters of the arterial compliance may be estimated in a least-squares manner.11-20-2008
20100004546FINGER ARTERIAL ELASTICITY MEASURING PROGRAM, FINGER ARTERIAL ELASTICITY MEASURING DEVICE AND FINGER ARTERIAL ELASTICITY MESAURING METHOD - PROBLEMS TO BE SOLVED: A finger arterial elasticity measuring program, a finger arterial elasticity measuring device and a finger arterial elasticity measuring method are provided for making it possible to measure an elasticity index of a finger artery in accordance with a pulse wave of a finger artery without measuring a blood pressure in evaluating the elasticity of the finger artery related to the degree of arterial sclerosis in an easy and least expensive manner.01-07-2010
20100280395System and Method for Hypertension Management11-04-2010
20100280396System for Cardiac Pathology Detection and Characterization - A system for heart performance characterization and abnormality detection includes an interface for receiving an electrical signal comprising a pressure indicative waveform indicating a heart blood pressure of a patient over a heart beat cycle. A timing detector determines multiple different time periods in at least one heart cycle from the pressure indicative waveform. A patient monitor monitors the multiple different time periods and in response to detection of a variation in at least one of the multiple different time periods exceeding a predetermined threshold or range, generates an alert message associated with the variation.11-04-2010
20080200819Orthostasis detection system and method - The disclosed embodiments relate to a system and method for monitoring patient data. An exemplary method comprises obtaining hemodynamic variation data that corresponds to a variation in intravascular hemodynamics of a patient, searching the hemodynamic variation data for an indication of orthostasis in response to the occurrence of a positional maneuver of or by the patient, and generating an output if the indication orthostasis is discovered.08-21-2008
20100204589NON-INVASIVE INTRACRANIAL PRESSURE SENSOR - A system and method for non-invasively detecting intracranial pressure (ICP) of a living being by detecting impedance mismatches between carotid arteries and cerebral vessels via a reflection of the carotid pressure waveform using a pressure sensor positioned against the palpable carotid artery, as well as analyzing the reflection and comparing the analysis with known cerebral vasculature data, to calculate ICP non-invasively. A remote blood pressure waveform can also be used to compensate for blood system impedance.08-12-2010
20120143068COMPUTERIZE HEALTH MANAGEMENT METHOD AND HEALTH MANAGEMENT ELECTRONIC DEVICE - A computerized health management method and a health management electronic device are provided. The computerized health management method includes the following steps. A blood pressure curve of a user is measured. A systolic pressure and a diastolic pressure of the blood pressure curve are calculated by a microprocessor. A high blood pressure risk level of the user is analyzed by the microprocessor according to the systolic pressure and the diastolic pressure. A cardiovascular disease risk level of the user is analyzed by the microprocessor according to the high blood pressure risk level. A measuring frequency for measuring the blood pressure is suggested to the user by the microprocessor according to the high blood pressure risk level or the cardiovascular disease risk level.06-07-2012
20090182238Method of predicting a blood pressure trend by blood pressure measurements - The present invention discloses a method of predicting a blood pressure trend by blood pressure measurements, and the method allows users to select a number of times for measuring blood pressures as a cycle according to a doctor's recommendation or a personal preference, and automatically calculates and stores an average of blood pressures of the cycle (including systolic and diastolic blood pressures). With the variation of average blood pressures of previous and next cycles, users can know about the variation of the trends of their systolic and diastolic blood pressures quickly and easily. The trend of blood pressures is provided as a reference for users to adjust their living habits and for medical professionals to diagnose a patient's condition in hope of resuming the normal blood pressure of the patient.07-16-2009
20100204592Detection of Parameters in Cardiac Output Related Waveforms - Methods for detecting parameters in cardiac output related waveforms are described. The methods include methods for detecting individual heart beat cycles in a cardiac output related waveform, methods for detecting an error in an assigned starting point for an individual heart beat cycle in a cardiac output related waveform, methods for detecting a dichrotic notch for an individual heart beat cycle in a cardiac output related waveform, and methods for detecting an error in an assigned dichrotic notch for an individual heart beat cycle in a cardiac output related waveform. The identification of these parameters is important for a clinician as these parameters form the basis for the calculation of many other cardiac output related parameters.08-12-2010
20100204591Calculating Cardiovascular Parameters - Methods for measuring a cardiovascular parameter in a subject regardless of whether the subject is experiencing normal hemodynamic or abnormal hemodynamic conditions are described. These methods involve the determination of whether a subject is experiencing normal hemodynamic conditions or abnormal hemodynamic conditions, then applying an appropriate model to subject data to determine a cardiovascular parameter for the subject. Multivariate Boolean models are used to establish if the subject is experiencing normal hemodynamic or abnormal hemodynamic conditions, then multivariate statistical models are used to calculate the appropriate cardiovascular parameter. Having correct cardiovascular parameters for a subject experiencing abnormal hemodynamic conditions, for example, enables the calculation of accurate values for treatment relevant parameters, such as, cardiac output and stroke volume.08-12-2010
20100204590Detection of Vascular Conditions Using Arterial Pressure Waveform Data - Multivariate statistical models for the detection of vascular conditions, methods for creating such multivariate statistical models, and methods for the detection of vascular condition in a subject using the multivariate statistical models are described. The models are created based on arterial pressure waveform data from a first group of subjects that were experiencing a particular vascular condition and a second group of subjects that were not experiencing the same vascular condition. The multivariate statistical models are set up to provide different output values for each set of input data. Thus, when data from a subject under observation is input into the model, the relationship of the model output value to the established output values for the two groups upon which the model was established will indicate whether the subject is experiencing the vascular condition.08-12-2010
20100204588METHOD AND APPARATUS FOR DETECTING MEASUREMENT SITE OF BLOOD PRESSURE - An apparatus and method which detects a blood-pressure measurement site. The apparatus for detecting a site of a body to measure blood pressure includes a sensing unit for sensing pressures applied to a blood vessel of a site of the body, a calculation unit for calculating a waveform representing the sensed pressure, and a determination unit for determining whether the site is the optimal site.08-12-2010
20090143687DEVICE AND METHOD FOR MANAGING, ARCHIVING AND/OR EVALUATING BLOOD PRESSURE DATA - A device and method for managing, archiving and/or evaluating blood pressure data of a plurality of patients. The blood pressure data is acquired using blood pressure monitors. The blood pressure data for each patient is separately stored in an individual storage space in a central data server. A network connection including at least one network terminal is used to input the data into the individual storage space and read out the data from the individual storage space. A control device controls access to the storage spaces by comparing a transmitted access code including a unique device identification code for the blood pressure monitor of the patient corresponding to the individual storage space with a unique access code corresponding to the individual storage space.06-04-2009
20110224556BODY-WORN VITAL SIGN MONITOR - The invention provides a body-worn vital sign monitor that measures a patient's vital signs (e.g. blood pressure, SpO2, heart rate, respiratory rate, and temperature) while simultaneously characterizing their activity state (e.g. resting, walking, convulsing, falling) and posture (upright, supine). The monitor processes this information to minimize corruption of the vital signs and associated alarms/alerts by motion-related artifacts. It also features a graphical user interface (GUI) rendered on a touchpanel display that facilitates a number of features to simplify and improve patient monitoring and safety in both the hospital and home.09-15-2011
20090326389Medical Therapy Device - A system and a method for synchronizing operation between a patient monitoring device and a patient treatment device are disclosed. The patient monitoring device and the patient treatment device are operatively connected via a network, for example, a patient area network (PAN) or a local area network (LAN). A controller with a display is configured to accept user input via a graphic user interface (GUI) and display a patient's physiological data and operating parameters of both the patient monitoring device and the patient treatment device. The operation is synchronized by starting to operate the patient monitoring device at a predetermined operating state of the patient treatment device, and delaying changes in the operating state of the patient treatment device, until the operation of the monitoring device is concluded or the operating state of the patient treatment device indicates an abort condition.12-31-2009
20100152592Assessment of Preload Dependence and Fluid Responsiveness - Methods for determining a cardiovascular parameter reflecting fluid or volume changes and for detecting arrhythmia are disclosed. These methods involve receiving a waveform dataset corresponding to an arterial blood pressure, pulseox, Doppler ultrasound or bioimpedance signal and analyzing the waveform to detect irregular cardiac cycles. Irregular cardiac cycles are detected, for example, by comparing parameters of individual cardiac cycles to the parameters of other or average cardiac cycles. If any irregular cardiac cycles are present, their effect is compensated for to form a modified waveform dataset. Once any irregular cardiac cycles are compensated for, a cardiovascular parameter reflecting fluid or volume changes using the modified waveform dataset is calculated. In the method for determining arrhythmia, if the number of irregular cardiac cycles exceeds a predetermined arrhythmia threshold, a user such as a medical professional is notified.06-17-2010
20090198140METHOD AND APPARATUS FOR EVALUATION OF FLUID RESPONSIVENESS - The present invention discloses a method and related apparatus for determining a cardiac parameter from either the arterial blood pressure signal or the photoplethysmographic signal to quantify the degree of amplitude modulation due to respiration (pulse pressure variation) and predict fluid responsiveness. The method involves the application of Lempel-Ziv complexity to a filtered and segmented physiologic signal for direct determination of the fluid status of a patient. Real-time monitoring of fluid status involves the implementation of the disclosed method as part of a bedside monitoring apparatus.08-06-2009
20090082677EXERCISE ASSISTING DEVICES - An exercise assisting device comprising a detector configured to detect at least one physiological data of a user, a control module configured to convert the at least one physiological data into at least one index in accordance with an algorithm, each of the at least one index being representative of an exercise performance level, a memory module including a first section configured to store a number of predetermined data related to a number of exercise performance levels, a second section configured to store the at least one index, and a third section configured to store the algorithm, and a display module configured to display at least one of the number of predetermined data in accordance with the at least one index.03-26-2009
20110230773METHOD OF DERIVING CENTRAL AORTIC SYSTOLIC PRESSURE VALUES AND METHOD FOR ANALYSING AN ARTERIAL DATASET TO DERIVE THE SAME - A method, system and computer readable medium for deriving central aortic systolic pressure by reversing the order of a set of predetermined number of blood pressure measurements to obtain a reversed blood pressure set; averaging the reversed blood pressure set such that the average set represents a moving average waveform; overlaying the reversed blood pressure set and the moving average waveform; identifying a point of intersection on the reversed arterial waveform and the moving average waveform, and setting the central aortic systolic pressure as a reversed blood pressure value in the reversed blood pressure set nearest to the point of intersection.09-22-2011
20110230771HEART FAILURE STATUS MONITORING - Left atrial pressure and temperature of a patient are monitored to identify a normal wake state, a normal sleep state, and any deviation from those normal states (e.g., an alarm state). In the event an alarm state is identified, a determination is made as to whether to generate an indication of heart failure exacerbation based on a heart failure score. In addition, congestion and perfusion in a patient may be monitored over time to provide a two-dimensional indication of a trend relating to the heart failure status of the patient.09-22-2011
20120078123PULSE WAVE ANALYZER AND BLOOD PRESSURE ESTIMATOR USING THE SAME - In a pulse wave analyzer, an ECG signal and a pulse wave signal are detected from an object to be analyzed. A plurality of feature points are extracting from the acquired ECG signal, the feature points appearing in a waveform of the ECG signal. The acquired pulse wave signal is segmented into a plurality of pulse wave signal pieces based on times at which the feature points appear. Each of the pulse wave signal pieces is segmented every heart beat. A reference pulse wave is calculated based on the plurality of pulse wave signal pieces, by multiplying the pulse wave signal pieces by coefficients and averaging the pulse wave signal pieces multiplied by the coefficients. The reference pulse wave is used to estimate the blood pressure of the object.03-29-2012
20100274141MEASURES OF CARDIAC CONTRACTILITY VARIABILITY DURING ISCHEMIA - Systems and methods include obtaining a measure of cardiac contractility. A cardiac contractility variability is determined from the measure of cardiac contractility. Analyzing the cardiac contractility variability, an indication of cardio-vasculature health is provided.10-28-2010
20080214942APPARATUS AND METHOD FOR MEASURING BLOOD PRESSURE - Disclosed are an apparatus and method for measuring a blood pressure capable of enhancing accuracy and reliability for a blood pressure. According to the apparatus and method, a blood pressure is obtained by using a pulse transit time (PTT) calculated based on a pulse wave measured with a minimized error, a subject's body information, pulse analysis information, and environment information together measured when measuring the pulse wave.09-04-2008
20100160796BODY-WORN SYSTEM FOR MEASURING CONTINUOUS NON-INVASIVE BLOOD PRESSURE (cNIBP) - The present invention provides a technique for continuous measurement of blood pressure based on pulse transit time and which does not require any external calibration. This technique, referred to herein as the ‘Composite Method’, is carried out with a body-worn monitor that measures blood pressure and other vital signs, and wirelessly transmits them to a remote monitor. A network of body-worn sensors, typically placed on the patient's right arm and chest, connect to the body-worn monitor and measure time-dependent ECG, PPG, accelerometer, and pressure waveforms. The disposable sensors can include a cuff that features an inflatable bladder coupled to a pressure sensor, three or more electrical sensors (e.g. electrodes), three or more accelerometers, a temperature sensor, and an optical sensor (e.g., a light source and photodiode) attached to the patient's thumb.06-24-2010
20100217135METHOD AND SYSTEM FOR INTERPRETING HEMODYNAMIC DATA INCORPORATING PATIENT POSTURE INFORMATION - Systems and methods for improving hemodynamic data interpretation by accounting for the effects of patient posture is disclosed. In certain embodiments, a posture signal is acquired and used to categorize hemodynamic data according to posture to facilitate distinguishing posture-related changes in acquired hemodynamic data from those due to pathophysiologic changes. Posture information may be used to normalize data acquired in various postures to facilitate interpretation of such data. Baseline measurements of hemodynamic data acquired in various postures may also be used to subsequently detect changes in patient posture without the need for an implanted posture sensor.08-26-2010
20100241012Portal Vein Pressure Measurement Using Elastography - The shear stiffness of a subject's spleen is measured using elastography techniques such as ultrasound elastography or a magnetic resonance elastography (MRE) acquisition with an MRI system. A relationship between splenic shear stiffness and portal venous blood pressure is modeled and is used to calculate portal venous blood pressure non-invasively from the measured splenic shear stiffness.09-23-2010
20100241013Direct Measurements of Arterial Pressure Decoupling - Methods for monitoring central-to-peripheral arterial pressure decoupling, i.e., hyperdynamic or vasodilation conditions are described. These methods involve the comparison of parameters such as impedance, compliance, and pressure that can be determined from flow and pressure measurements at central aortic and peripheral arterial locations. The relationship between the parameters at the central aortic and peripheral arterial locations provides an indication of central-to-peripheral arterial pressure decoupling. These methods can be alert a user that a subject is experiencing central-to-peripheral arterial pressure decoupling, which can enable a clinician to appropriately provide treatment to the subject.09-23-2010
20120143067SYSTEMS AND METHODS FOR DETERMINING WHEN TO MEASURE A PHYSIOLOGICAL PARAMETER - Systems and methods are provided for determining when to update a blood pressure measurement. The value of a physiological metric may be monitored and compared to a reference value. A patient monitoring system may compute a difference between a monitored metric and a reference value, and compare the difference to a threshold value to determine whether to update a blood pressure measurement. The threshold value may be constant or variable, and may depend on the monitored metric.06-07-2012
20100198085Disposable Sensor Device and Monitoring System - The invention relates to a disposable sensor device (08-05-2010
20100198086EXTENDED OPTICAL RANGE SYSTEM FOR MONITORING MOTION OF A MEMBER - A system and method for monitoring a physiological parameter includes a garment that includes a fabric that exhibits both a light transmission property and a light reflection property. The amount of light transmitted through the fabric relative to the amount of light reflected by the fabric changes when the fabric stretches in response to motion, such as the motion induced by physiological activity (e.g., heart rate). The system includes at least one source of radiation having wavelength(s) in the range of 400 to 2200 nanometers and at least one detector responsive to such incident radiation. The source and detector are associated with the fabric such that the reception of incident radiation by the detector is directly affected by a change in the amount of light transmitted through the fabric relative to the amount of light reflected by the fabric when the fabric stretches. A signal processor converts a signal from the detector into a signal representative of at least one predetermined physiological parameter of a wearer of the garment.08-05-2010
20110034814METHOD AND DEVICE FOR MONITORING A VASCULAR ACCESS AND EXTRACORPOREAL BLOOD TREATMENT DEVICE COMPRISING A DEVICE FOR MONITORING VASCULAR ACCESS - The invention relates to a method and a device for monitoring a vascular access during an extracorporeal blood treatment. The method and the device according to the invention are based on the monitoring of the difference between the venous pressure measured by a venous pressure sensor and the arterial pressure measured by an arterial pressure sensor (in the extracorporeal blood circuit. According to the method and the device according to the invention, a test function describing disturbances in the extracorporeal blood circuit is determined. Said test function is used to determine a noise-free differential pressure from the measured venous and arterial pressure, said differential pressure being evaluated in an arithmetic and evaluation unit to identify a defective vascular access.02-10-2011
20090069700Method for processing of continuous pressure-related signals derivable from locations inside or outside a human body or body cavity - This invention describes a method for processing pressure signals derivable from locations inside or outside a human or animal body or body cavity. Different aspects of the invention relate to a method for optimal differentiating between cardiac beat- and artifact-induced pressure waves, a method for obtaining new and improved information from said pressure signals. In particular, this invention describes the use of said inventive method for processing of pressure signals for controlling an adjustable shunt valve. The method can be incorporated in a processing unit of a device for use in draining fluid from a brain or spinal fluid cavity.03-12-2009
20090069698BLOOD PRESSURE MEASURING APPARATUS AND METHOD OF MEASURING BLOOD PRESSURE - Provided is a blood pressure measuring apparatus and a method of measuring blood pressure. The blood pressure measuring apparatus includes a plurality of blood pressure measuring units disposed on a substrate, a plurality of optical sensors disposed on the substrate to correspond to the blood pressure measuring units, and a control unit that measures blood pressure by analyzing signals received from the optical sensors and the blood pressure measuring units, wherein each of the blood pressure measuring units comprises a plurality of blood pressure sensors.03-12-2009
20100312125System for Cardiac Pathology Detection and Characterization - A system for heart performance characterization and abnormality detection includes an interface for receiving digitized electrical signals representing blood pressure waveforms over one or more heart beat cycles. The digitized electrical signals comprise, a first digital data sequence representing normal blood pressure of a patient, a second digital data sequence representing random blood pressure of a normal patient and a third digital data sequence representing a potentially abnormal blood pressure of a patient. A complexity processor calculates first, second and third complexity indices for the corresponding first, second and third digital data sequences respectively. A correlation processor uses the calculated first, second and third complexity indices to calculate one or more measures indicating deviation of the potentially abnormal blood pressure of the patient from a normal value.12-09-2010
20110172546ARTERIAL-WALL STIFFNESS EVALUATION SYSTEM - An arterial-wall stiffness evaluation system of the present invention includes: a cuff to be attached to a part of a living body; a pressure sensor for detecting pressure in the cuff; a cuff-pressure control section for controlling the pressure in the cuff to be increased or decreased up to a predetermined value, based on a value detected by the pressure sensor; and a data processing section for calculating, based on pulse waves detected by the pressure sensor, pulse-wave amplitudes of cuff-pressure pulse waves and blood-pressure pulse waves, and for evaluating arterial-wall stiffness based on the pulse-wave amplitudes. The arterial-wall stiffness is evaluated by a pressure-diameter characteristic curve, which represents a relationship between vascular diameter and transmural pressure applied to a vascular wall, or by estimation from shapes and amplitudes of the detected pulse waves. Alternatively, the evaluation is performed by estimating, from the detected pulse waves, a differential function obtainable by differentiating a pressure-diameter characteristic curve with respect to a transmural pressure, or by use of an arctan or a sigmoid function. This allows anybody to easily evaluate blood vessel stiffness anytime with high accuracy even at home without any special knowledge.07-14-2011
20110172545Active Physical Perturbations to Enhance Intelligent Medical Monitoring - Tools and techniques for enhancing intelligent medical monitoring, and in particular monitoring that employs models for estimating and/or predicting physiological conditions. In an aspect, some of these tools and techniques employ active physical perturbation of a test subject (or patient), to induce physiological changes in the subject. By monitoring one or more of the patient's physiological parameters shortly before, during, and/or after the physical perturbation, the subject's reaction to the perturbation can be determined, and this reaction can be used to estimate and/or predict the subject's physiological state and/or clinical condition. In a particular case, the subject's response to the physical perturbation can be used to construct and/or refine a model that can be applied to analyze the subject's physiological parameters to produce such predications and/or estimations.07-14-2011
20130144176NON-INVASIVE BLOOD PRESSURE SENSOR - A non-invasive pressure measurement device measures pressure of fluid in a conduit via a piezoelectric transducer positioned proximate to the conduit having a fluid passing therethrough. The piezoelectric transducer is in communication with the conduit via a plate member having a protrusion extending outward from one side of the member. In one application, the device continuously measures blood pressure without the need for an inflatable cuff. Also, the device can detect and measure heart beat pulses from the fluid and utilize heart beat pulse information to provide further characteristics pertaining to the fluid in the conduit.06-06-2013
20110245690SYSTEMS AND METHODS FOR MEASURING ELECTROMECHANICAL DELAY OF THE HEART - Systems and methods are disclosed herein for measuring the electromechanical delay of the heart of a patient. An electrocardiogram (EKG) signal may be used to detect heart electrical activity. Photoplethysmograph (PPG) signals may be used to detect heart mechanical activity. The electromechanical delay may be calculated based at least in part on the timing of an EKG signal and at least two PPG signals.10-06-2011
20110034813METHODS AND APPARATUS FOR DETERMINING CARDIAC OUTPUT - The present invention provides methods and apparatus for determining a dynamical property of the systemic or pulmonary arterial tree using long time scale information, i.e., information obtained from measurements over time scales greater than a single cardiac cycle. In one aspect, the invention provides a method and apparatus for monitoring cardiac output (CO) from a single blood pressure signal measurement obtained at any site in the systemic or pulmonary arterial tree or from any related measurement including, for example, fingertip photoplethysmography.02-10-2011
20110034812PULMONARY ARTERY PRESSURE BASED SYSTOLIC TIMING INTERVALS AS A MEASURE OF RIGHT VENTRICULAR SYSTOLIC PERFORMANCE - Systems and methods include identifying a first portion and a second portion of a pulmonary artery pressure (PAP) signal during a cardiac cycle. A first timing interval between the first portion and the second portion is obtained and data related to the first timing interval is trended to provide a chronic physiological prognostic indicator. In an embodiment, a second timing interval is obtained from a third portion and a fourth portion of the PAP signal. Then, a function of the first and second timing intervals is trended to provide the chronic physiological prognostic indicator. In one instance, a ratio of the first interval to the second interval is calculated to provide an estimated right ventricle ejection fraction (RVEF) and the RVEF is trended.02-10-2011
20110040194METHOD AND SYSTEM FOR DETERMINING CARDIAC PARAMETERS - The present invention explains a method and system for providing all the relevant cardiac parameters in real time and in a fast manner, which are required for the cardiac analysis. The invention involves determining a first area and a second area, the first area under a waveform representing an aortic pressure, and extends between an onset of the systole and the end of the systole and the second area extends between a waveform representing a left ventricle pressure and a waveform adapted to represent the left atrium pressure of the same systole. The method further involves presenting a functional relationship between the first area and the second area on the one hand side and the cardiac parameters on the other hand side and then finally determining the cardiac parameters based on the first area and the second area by using the representation of the functional relationship.02-17-2011
20110040195METHOD AND APPARATUS TO DETERMINE THE END OF THE SYSTOLIC PART OF A PRESSURE CURVE - The invention relates to a method and an apparatus for determining the systolic phase interval (SP) of an arterial pressure curve with a starting point (t02-17-2011
20110245692METHOD AND SYSTEM FOR IMPROVING PHYSIOLOGIC STATUS AND HEALTH VIA ASSESSMENT OF THE DYNAMIC RESPIRATORY ARTERIAL PRESSURE WAVE USING PLETHYSMOGRAPHIC TECHNIQUE - The present invention specifies a method and system for assessing the dynamic respiratory arterial pressure wave using plethysmographic sensing techniques. The dynamic respiratory arterial pressure wave is measured and plotted for purposes of diagnosis and or remedial biofeedback.10-06-2011
20110245691NON-INVASIVE METHODS AND SYSTEMS FOR ASSESSING CARDIAC FILING PRESSURE - Featured are methods and systems for assessing cardiac filing pressure non-invasively. Such methods include, inter alia, arranging a photoplethysmography (PPG) transducer on a finger of a patient and fluidly coupling a pressure transducer to the patient's mouth so that the pressure transducer measures expiratory pressure. The PPG transducer provides an output of a pulse volume signal of cardiac circulatory flow. Such methods also including determining a pulse amplitude ratio, using the pulse volume near the end of the expiratory effort and a baseline pulse volume, and assessing the pulse amplitude ratio so as to determine a filing pressure condition for the heart of the patient.10-06-2011
20100137724METHOD AND AN APPARATUS FOR DETERMINATION OF BLOOD PRESSURE - The present invention relates to a method and an apparatus for non-interfering blood pressure measurements. In particular, the invention relates to an apparatus for continuously monitoring blood pressure for patients at home or at work. The apparatus comprises an extra-corporal sensor for blood pressure determination with a flexible housing adapted to be attached to the body of a living being proximate to an artery, and an electronic circuit for wireless coupling to a remote transceiver in accordance with the blood pressure in the artery, the remote transceiver adapted for wireless coupling to the sensor for generation of a pressure signal in accordance with the blood pressure in the artery, and a processor connected to the remote transceiver for reception of the pressure signal and adapted to estimate systolic and diastolic pressure based on the signal.06-03-2010
20110125033BLOOD PRESSURE ESTIMATION APPARATUS AND BLOOD PRESSURE ESTIMATION METHOD - [Problem to be Solved] To provide a non-invasive blood pressure estimation apparatus which can accurately estimate systolic blood pressure from blood flow sound of a dialysis patient and can continuously estimate systolic blood pressure by continuously picking up the blood flow sound of the subject.05-26-2011
20100210954SYSTEM AND METHOD FOR DETECTING ARTIFACTUAL HEMODYNAMIC WAVEFORM DATA - A system and method for cardiovascular analysis includes an implantable medical device capable of generating hemodynamic pressure waveform data based upon sensed pressure. Hemodynamic waveform data is analyzed to identify artifactual data represented in the hemodynamic waveform.08-19-2010
20110087116SYSTEM, METHODS AND DEVICES FOR MAINTENANCE, GUIDANCE AND/OR CONTROL - Methods, systems, devices and computer program products for providing maintenance, guidance and/or control of certain systems are disclosed. Typically, in some aspects the systems are complex. Also disclosed are methods, systems, devices and computer program products for providing therapeutic guidance for controlling a subject's circulation. One such method comprises the steps of: (i) determining the subject's present and desired circulatory states as a function of at least mean systemic filling pressure (Pms), heart efficiency (EH) and systemic vascular resistance (SVR); (ii) determining a target direction of a trajectory from the subject's present circulatory state to said subject's desired circulatory state, wherein treatment of the subject so as to traverse the trajectory will cause the subject's circulatory state to move towards a desired circulatory state; and (iii) visually representing the target direction of the trajectory.04-14-2011
20120245477MAGNETO-RESISTIVE EFFECT DEVICE, MAGNETIC HEAD GIMBAL ASSEMBLY, MAGNETIC RECORDING/REPRODUCTION DEVICE, STRAIN SENSOR, PRESSURE SENSOR, BLOOD PRESSURE SENSOR, AND STRUCTURAL HEALTH MONITORING SENSOR - According to one embodiment, a magneto-resistive effect device, includes a stacked body stacked on a substrate, a pair of first electrodes that feeds current to the stacked body, a strain introduction member, and a second electrode for applying a voltage to the strain introduction member. The stacked body includes a first magnetic layer that includes one or more metals selected from the group consisting of iron, cobalt, and nickel, a second magnetic layer stacked on the first magnetic layer, having a composition that is different from the first magnetic layer, and a spacer layer disposed between the first magnetic layer and the second magnetic layer.09-27-2012
20120245476IMPLANTABLE MEDICAL DEVICE - An implantable medical device includes an integrated or connectable implantable three-dimensional acceleration sensor, and a ballistocardiogram (BCG) capturing unit that is connected or connectable to the acceleration sensor. The BCG evaluation unit processes an acceleration signal provided by the acceleration sensor and derives a BCG from the 3D accelerometer output signal. A BCG evaluation unit is connected to the BCG capturing unit, and is designed to evaluate a BCG provided by the BCG capturing unit and supply an output signal representing stroke volume.09-27-2012
20100056930RAPID NON-INVASIVE BLOOD PRESSURE MEASURING DEVICE - A measurement device for generating an arterial volume-indicative signal includes an exciter and a detector. The exciter is adapted to receive an oscillating signal and generate a pressure wave based at least in part on the oscillating signal on the artery at a measurement site on a patient. The pressure wave includes a frequency. The detector is placed sufficiently near the measurement site to detect a volumetric signal indicative of arterial volume of the patient.03-04-2010
20090216133SYSTEMS AND METHODS FOR DETERMINING VESSEL COMPLIANCE - The disclosure of the present application provides for systems and methods for determining a phasic change in a vessel and vessel compliance. In at least one exemplary method for determining a phasic change in a vessel, the method comprises the steps of introducing a device into a site within a vessel, operating the device in connection with two or more fluid injections in the vessel to obtain two or more conductance values, calculating a parallel conductance value and a total conductance value, and calculating a phasic change in at least one vessel parameter based in part upon the calculated parallel conductance value and the calculated total conductance value. In an exemplary method for determining vessel compliance, the method comprises, in part, the steps of calculating a first vessel parameter and a second vessel parameter based on at least two conductance values, calculating a change in vessel parameter based upon the first and second vessel parameters, and calculating vessel compliance based upon the relationship between the change in vessel parameter and a change in pressure during a cardiac cycle.08-27-2009
20110178415CONTINUOUS, NON-INVASIVE, OPTICAL BLOOD PRESSURE MONITORING SYSTEM - The invention comprises a system of wearable devices that collectively allow for the continuous, non-invasive, measurement and monitoring of blood pressure, without the use of an inflatable cuff. The system incorporates: 1) An optical module, which is comprised of a coherent source of light, a semi-transparent hologram, microscope optics for viewing the interference pattern developed between the illuminated hologram and arterial blood, a spatial light modulator (SLM), and processing electronics with Bluetooth capability that facilitates digitization and wireless transmission of the fringe pattern to, 2) a personal digital assistant (PDA) that is worn on a waist belt. The PDA and associated software allow for continuous calculation and monitoring of real-time arterial blood pressure from the digitized fringe patterns received. The system further comprises 3) a personal computer (PC) with wireless capacity and connection to the internet. Continuous BP function, alerts, condition and medical assessment is conducted through PDA-PC communications with internet based medical facility.07-21-2011
20110077532Method and Apparatus for Assessment of Fluid Responsiveness - Methods and apparatus for determining a cardiac parameter from cardiovascular pressure signals including arterial blood pressure (ABP) and the photoplethysmographic signal to quantify the degree of amplitude modulation due to respiration and predict fluid responsiveness are disclosed. Disclosed embodiments include a method for assessing fluid responsiveness implemented in a digital computer with one or more processors comprising: (a) measuring a cardiovascular signal, and (b) computing a dynamic index predictive of fluid responsiveness from said cardiovascular signal using a nonlinear state space estimator. According to one particular embodiment, and without limitation, the nonlinear state space estimator is based on a model for cardiovascular signals such as arterial blood pressure or plethysmogram signals, and employs a marginalized particle filter to estimate a dynamic index predictive of fluid responsiveness that is substantially equivalent to a variation in pulse pressure of said cardiovascular signal.03-31-2011
20110077533APPARATUS FOR ASSESSING RISK OF CEREBROVASCULAR DISEASES - The apparatus for assessing the risk of cerebrovascular diseases comprises a sensor part 03-31-2011
20110071407DEVICE FOR ACQUIRING PHYSIOLOGICAL VARIABLES MEASURED IN A BODY - The present invention relates to an eavesdropping device for monitoring measured physiological variables of an individual, which eavesdropping device comprises a receiver and a communication interface. The eavesdropping device of the present invention is typically applied in a system comprising a first sensor arranged to be disposed in or outside the body of the individual for measuring aortic blood pressure P03-24-2011
20130165800ARM-WORN BLOOD PRESSURE MONITOR - A method employed in a prior art arm-worn blood pressure monitor to measure the height position of the heart has been an indirect method that merely estimates the position of the heart, and therefore has had the problems that the measurement accuracy and the reliability of the measurement are low, and that the measuring position is awkward and it is difficult to achieve correct position alignment. An arm-worn blood pressure monitor includes a cuff, a microwave transmitting unit for radiating a microwave onto a human subject, a microwave receiving unit for receiving a reflected wave Doppler-shifted relative to the radiated microwave due to a heartbeat of the subject, and a correct position detector for detecting, based on the reflected wave, whether the cuff worn around an arm of the subject is located in a correct position relative to the position of the heart of the subject.06-27-2013
20100063405SYSTEMS, DEVICES AND METHODS FOR NONINVASIVE OR MINIMALLY-INVASIVE ESTIMATION OF INTRACRANIAL PRESSURE AND CEREBROVASCULAR AUTOREGULATION - The systems, devices, and methods described herein provide for the estimation and monitoring of cerebrovascular system properties and intracranial pressure (ICP) from one or more measurements or measured signals. These measured signals may include central or peripheral arterial blood pressure (ABP), and cerebral blood flow (CBF) or cerebral blood flow velocity (CBFV). The measured signals may be acquired noninvasively or minimally-invasively. The measured signals may be used to estimate parameters and variables of a computational model that is representative of the physiological relationships among the cerebral flows and pressures. The computational model may include at least one resistive element, at least one compliance element, and a representation of ICP.03-11-2010
20120277600MEASUREMENT OF CARDIAC CYCLE LENGTH AND PRESSURE METRICS FROM PULMONARY ARTERIAL PRESSURE - A method and apparatus for monitoring a cardiovascular pressure signal in a medical device that includes determining whether the sensed pressure signal is greater than a first pressure threshold, determining a first metric of the pressure signal in response to the sensed pressure signal being greater than the first pressure threshold, determining whether the sensed pressure signal is greater than a second pressure threshold not equal to the first pressure threshold, determining a second metric of the pressure signal in response to the sensed pressure signal being greater than the first pressure threshold, and determining at least one of a systolic pressure or a diastolic pressure, wherein the at least one of a systolic pressure or a diastolic pressure is determined based on the first metric in response to the pressure signal not being greater than the second threshold, and based on the second metric in response to the pressure signal being greater than the second threshold.11-01-2012
20120277599MEASUREMENT OF CARDIAC CYCLE LENGTH AND PRESSURE METRICS FROM PULMONARY ARTERIAL PRESSURE - A method and apparatus for monitoring a cardiovascular pressure signal in a medical device that includes comparing the sensed pressure signal to a first pressure threshold, identifying a first sense greater than the first pressure threshold, determining a metric of the pressure signal in response to the identified first sense, comparing the sensed pressure signal to a second pressure threshold not equal to the first pressure threshold in response to the identified first sense, identifying a second sense, subsequent to the first sense, greater than the second pressure threshold, identifying a third sense, subsequent to the first sense, greater than the first pressure threshold, and determining a cycle length corresponding to electrical activity of a heart in response to one of the first sense and the third sense or the second sense and the third sense.11-01-2012
20090112102Therapy device with a time-variable blood regulation - A therapy device having a blood pressure device and a regulating device for a time-variable regulation of the blood pressure, which decides, during a therapy procedure, dependent on detected blood pressure value, whether the blood regulation is continued with hypothetical or with real blood pressure values. The regulating device processes various categories of blood pressure values, i.e. blood pressure values obtained by the regulating device according to an implemented time schedule, blood pressure values requested by measurement and evaluation device, and blood pressure values requested by medical staff. Besides the regular triggers (RT) generated at regular intervals, the irregular triggers (IRT) and the quasi-regular triggers (QRT) requested externally at respective times are also evaluated.04-30-2009
20110257537BLOOD PRESSURE MONITORING SYSTEM PROVIDING ENHANCED VASCULAR ANEURYSM DETECTION FEATURES AND RELATED METHODS - A blood pressure monitoring system may include a plurality of a blood pressure measuring devices each configured to measure blood pressure of a respective extremity of a patient, and a blood pressure monitoring device. The blood pressure monitoring device may include at least one interface device configured to interface with the plurality of blood pressure measuring devices, and a controller coupled to the at least one interface device. The controller may be configured to cooperate with the plurality of blood pressure measuring devices to determine respective blood pressure measurements for each patient extremity, selectively determine differences between the blood pressure measurements, and generate an indication of a probable vascular aneurysm based upon a determined difference between at least two of the blood pressure measurements reaching a vascular aneurysm threshold value.10-20-2011
20080249422Method and system for improving physiologic status and health via assessment of the dynamic respiratory arterial pressure wave using plethysmographic technique - The present invention specifies a method and system for assessing the dynamic respiratory arterial pressure wave using plethysmographic sensing techniques. The dynamic respiratory arterial pressure wave is measured and plotted for purposes of diagnosis and or remedial biofeedback.10-09-2008
20080214941Blood Pressure Measuring Device and a Method for Operating a Blood Pressure Measuring Device - A blood pressure self-monitoring device includes an alarm generator to remind the patient to carry out blood pressure measurements according to a predetermined schedule. The device performs a specific phase of measuring blood pressure according to a clinically validated criterion, and calculates an accurate blood pressure reading on the basis of plural measurement values. The device also has a therapeutic decision mode, which can monitor blood pressure for assessing the effect of antihypertensive drug treatment. In the extended mode, the alarm generator works according to a predetermined daily measurement to remind the patient to take a blood pressure measurement following drug intake. Also during the treatment phase, the antihypertensive drug may affect the probability of irregular heartbeat, which can be a reference index for assessing the types and doses of treated antihypertensive drug. The device can also use a selectable switch to operate as a regular home blood pressure monitor.09-04-2008
20110054328BIOLOGICAL INFORMATION MONITOR - A biological information monitor includes: a first measuring unit which measures a pulse wave propagation time of a patient; a second measuring unit which measures a blood pressure of the patient; a calculating unit which calculates an estimated blood pressure value of the patient based on the pulse wave propagation time of the patient; a setting unit which sets a threshold; and a determining unit which compares the estimated blood pressure value with the threshold. The second measuring unit is activated to measure the blood pressure of the patient at least one of at time intervals and at a time when an operator operates the second measuring unit, and the second measuring unit is activated to measure the blood pressure of the patient by the determining unit based on the comparison result.03-03-2011
20110166458METHOD AND APPARATUS FOR NON-INVASIVELY MEASURING HEMODYNAMIC PARAMETERS USING PARAMETRICS - An improved method and apparatus for non-invasively assessing one or more hemodynamic parameters associated with the circulatory system of a living organism. In one aspect, the invention comprises a method of measuring a hemodynamic parameter (e.g., arterial blood pressure) by applanating or compressing portions of tissue proximate to the blood vessel of concern until a desired condition is achieved, and then measuring the hemodynamic parameter. Such applanation effectively mitigates transfer and other losses created by the tissue proximate to the blood vessel, thereby facilitating accurate and robust tonometric measurement. An algorithm adapted to maintain optimal levels of applanation is also described. Methods and apparatus for scaling such hemodynamic parameter measurements based on subject physiology, and providing treatment to the subject based on the measured parameters, are also disclosed.07-07-2011
20110263991METHOD AND APPARATUS FOR CONTROL OF NON-INVASIVE PARAMETER MEASUREMENTS - Improved methods and apparatus for non-invasively assessing one or more parameters associated with fluidic systems such as the circulatory system of a living organism, when such parameters are potentially affected by other concurrent events. In one exemplary embodiment, apparatus and methods for compensating for occlusive events (e.g., pressure cuff inflation) occurring ipsilateral to the location of parameter measurement are disclosed. Upon passive detection of signal degradation resulting from the event, the apparatus selectively enters a “wait state” wherein further processing of the hemodynamic data is suspended until the degrading event subsides. This behavior mitigates any adverse effects the event might have on the accuracy of the representation of the measured hemodynamic parameter generated by the system. In another exemplary embodiment, the measured data is analyzed in order to classify the type of event (e.g., occlusive or other), such classification allowing the system to appropriately tailor its response to the event.10-27-2011
20100292584SPECTRUM ANALYTICAL METHOD FOR QUANTIFYING HEAT-LUNG INTERACTION - The present invention is related to a spectrum analytical method for quantifying hear-lung interaction, which can estimate cardiac function by using a heart-associated monitoring signal. According to the method of the present invention, quantification of heart-lung interaction is conducted by choosing spectrum signals within a specified frequency band, such that the interference to the heart-associated monitoring signals by incidental events occurring at a low frequency, can be avoided. Therefore, the method of the present invention can be performed even in the subjects who are not in a state of general anesthesia or sedation, and hence is very useful in estimating the cardiac function of the test subjects.11-18-2010
20110125034VESSEL WALL MONITORING APPARATUS - A vessel wall monitoring apparatus includes: a first detecting unit which detects vessel diameter information based on first biological information obtained from a subject; a first producing unit which differentiates the vessel diameter information detected by the first detecting unit, to produce a vessel diameter function; a second detecting unit which detects blood pressure based on second biological information obtained from the subject; a second producing unit which performs a logarithmic operation on the blood pressure detected by the second detecting unit, to produce a logarithmic blood pressure function; and an outputting unit which produces an impedance model expression by using the vessel diameter function, the logarithmic blood pressure function, and mechanical characteristic values including a stiffness, viscosity, and inertia, and which calculates and outputs at least one of the stiffness, the viscosity, and the inertia based on the impedance model expression.05-26-2011
20110009755ARTERIAL BLOOD PRESSURE MONITORING DEVICES, SYSTEMS AND METHODS FOR USE WHILE PACING - Provided herein are implantable systems, and methods for use therewith, for monitoring a patient's arterial blood pressure while a patient's heart is being paced. A signal (e.g., PPG or IPG signal) indicative of changes in arterial blood volume remote from the patient's heart is obtained using a sensor or electrodes that are implanted remote from the patient's heart. One or more metrics indicative of pulse arrival time (PAT) are determined, where each metric can be determined by determining a time from a paced cardiac event to one or more predetermined features of the signal indicative of changes in arterial blood volume. Based on at the metric(s) indicative of PAT, arterial blood pressure is estimated, which can include determining values indicative of systolic blood pressure, diastolic blood pressure, pulse pressure and/or mean arterial blood pressure, and/or changes in such values.01-13-2011
20100121204BLOOD VESSEL STATE EVALUATING DEVICE, BLOOD VESSEL STATE EVALUATING METHOD, AND COMPUTER-READABLE RECORDING MEDIUM STORING BLOOD VESSEL STATE EVALUATING PROGRAM - A phase line tilt calculating unit (actual measurement) receives phase characteristics Pa(f) and Pb(f) outputted from frequency conversion units, and calculates phase difference characteristics of actual measurement based on a phase difference on each frequency component between the phase characteristics. A phase line tilt calculating unit (model) calculates phase difference characteristics between a transfer function Ga(f) and a transfer function Gb(f) calculated by a transfer function calculating unit, and outputs the calculated phase difference characteristics to a search unit. The search unit fits a variable k and determines a variable k05-13-2010
20110137183EVALUATE AORTIC BLOOD PRESSURE WAVEFORM USING AN ADAPTIVE PERIPHERAL PRESSURE TRANSFER FUNCTION - The invention relates to method for reconstructing an aortic blood pressure waveform of a person from a peripheral blood pressure waveform of the person comprising the steps of determining at least one pre-selected parameter of the peripheral blood pressure waveform, reconstructing the aortic blood pressure waveform from the peripheral blood pressure waveform using a pressure transfer function having at least one adjustable characteristics, wherein said adjustable characteristics is determined using the at least one pre-selected parameter of the peripheral blood pressure waveform. The invention further relates to a device for reconstructing an aortic blood pressure waveform from a peripheral blood pressure waveform and a computer program product.06-09-2011
20110137182METHODS AND DEVICES FOR ASSESSING INTRACRANIAL PRESSURE - Provided are methods for noninvasively assessing intracranial pressure (“ICP”) based on optic nerve sheath diameter (“ONSD”) and a blood velocity metric, such as pulsatility or resistivity index. Also provided are related devices and systems for performing the claimed methods.06-09-2011
20080306393Deriving Central Aortic Systolic Pressure and Analyzing Arterial Waveform Data to Derive Central Aortic Systolic Pressure Values - A method of deriving central aortic systolic pressure comprises (a) creating a set having a predetermined number of blood pressure measurements, the set representative of an arterial waveform; (b) determining an integer interval value; (c) averaging a series of consecutive blood pressure measurement readings in the set equal to the integer interval value commencing from the f12-11-2008
20110263990RAPID NON-INVASIVE BLOOD PRESSURE MEASURING DEVICE - A measurement device for generating an arterial volume-indicative signal includes an exciter and a detector. The exciter is adapted to receive an oscillating signal and generate a pressure wave based at least in part on the oscillating signal on the artery at a measurement site on a patient. The pressure wave includes a frequency. The detector is placed sufficiently near the measurement site to detect a volumetric signal indicative of arterial volume of the patient.10-27-2011
20100160795BODY-WORN SYSTEM FOR MEASURING CONTINUOUS NON-INVASIVE BLOOD PRESSURE (cNIBP) - The present invention provides a technique for continuous measurement of blood pressure based on pulse transit time and which does not require any external calibration. This technique, referred to herein as the ‘Composite Method’, is carried out with a body-worn monitor that measures blood pressure and other vital signs, and wirelessly transmits them to a remote monitor. A network of body-worn sensors, typically placed on the patient's right arm and chest, connect to the body-worn monitor and measure time-dependent ECG, PPG, accelerometer, and pressure waveforms. The disposable sensors can include a cuff that features an inflatable bladder coupled to a pressure sensor, three or more electrical sensors (e.g. electrodes), three or more accelerometers, a temperature sensor, and an optical sensor (e.g., a light source and photodiode) attached to the patient's thumb.06-24-2010
20100160797BODY-WORN SYSTEM FOR MEASURING CONTINUOUS NON-INVASIVE BLOOD PRESSURE (cNIBP) - The present invention provides a technique for continuous measurement of blood pressure based on pulse transit time and which does not require any external calibration. This technique, referred to herein as the ‘Composite Method’, is carried out with a body-worn monitor that measures blood pressure and other vital signs, and wirelessly transmits them to a remote monitor. A network of body-worn sensors, typically placed on the patient's right arm and chest, connect to the body-worn monitor and measure time-dependent ECG, PPG, accelerometer, and pressure waveforms. The disposable sensors can include a cuff that features an inflatable bladder coupled to a pressure sensor, three or more electrical sensors (e.g. electrodes), three or more accelerometers, a temperature sensor, and an optical sensor (e.g., a light source and photodiode) attached to the patient's thumb.06-24-2010
20110152697Circulatory Pressure Monitoring Using Infusion Pump Systems - A low cost, transportable system for monitoring the central venous pressure of a patient receiving an infusion is provided. The pressure monitoring system of the present invention employs a pump and a flow meter in order to supply infusion fluids to a patient. Based upon the control factors and changes thereof communicated to the pump by a controller in order to achieve and maintain a desired infusion fluid flow rate, relative changes in patient's venous pressure and/or quantitative pressure data is obtained.06-23-2011
20100030087ESTIMATING CARDIOVASCULAR PRESSURE AND VOLUME USING IMPEDANCE MEASUREMENTS - Techniques for estimating a cardiac chamber or vascular pressure based upon impedance are described. A device or system may measure an impedance between at least two electrodes implanted within or proximate to a cardiovascular system. The device or system may estimate a pressure of an element of the cardiovascular system based on a relationship between impedance and volume of the element, and based on a empirical relationship between the volume and the pressure. The device or system may also estimate the dimension of the element based on the impedance-volume relationship, or other characteristics based on the impedance. Because the impedance measurements may be obtained, in some examples, by using electrodes and leads implanted within the cardiovascular system and coupled to an implantable medical device, a practical estimation of a cardiovascular pressure can be obtained on a chronic basis without requiring the use other invasive sensors, such as micronanometer transducers.02-04-2010
20100022895DIAGNOSIS SYSTEM OF DEFICIENT AND FORCEFUL PULSE - Disclosed herein is a system for diagnosing a deficient pulse and an forceful pulse. The system includes a pulse diagnotic device, a deficient pulse and forceful pulse determining device, and an output device. The pulse diagnotic device measures pulse condition information at an examinee's Cun (˜\f˜) Gu (H), and Chi (,R) pulse-taking locations on his or her wrist using one or more pulse-taking sensors. The deficient pulse and forceful pulse determining device is operably connected to the pulse diagnotic device, analyzes the pulse pressure information measured by the pulse diagnotic device, calculates a quantified deficiency/forceful coefficient, and determines whether a pulse of interest is a deficient pulse or an forceful pulse. The output device is connected to the determining device and displays results of the determination.01-28-2010
20100016736Estimating Aortic Blood Pressure from Non-Invasive Extremity Blood Pressure - Methods and a computer program product for using a circulatory measurement on an extremity of a particular subject to derive an aortic blood pressure for that subject. A model is constructed that maps a peripheral cardiovascular waveform to a central cardiovascular waveform on the basis of a plurality of model parameters. A time record is obtained using a non-invasive blood pressure sensor disposed at a solitary position periphery of the cardiovascular system of a subject. The time record is then transformed to obtain a plurality of test central blood pressure waves, with a single test central blood pressure wave is based on each of a plurality of sets of values of the model parameters. An optimum set of values of the model parameters is then selected, based on a specified criterion applied to the plurality of test central blood pressure waves, so that the aortic circulatory waveform of the subject can be obtained.01-21-2010
20100016734Systems and Methods Using Induced Perturbation to Determine Physiological Parameters - According to embodiments, systems and methods for non-invasive blood pressure monitoring are disclosed. An exciter may induce perturbations in a subject, and a sensor or probe may be used to obtain a detected signal from the subject. The detected signal may then be used to measure one or more physiological parameters of the patient. For example if the perturbations are based on a known signal, any differences between the known signal and the input signal may be attributable to the patient's physiological parameters. A phase drift between the perturbation signal and the detected signal may be determined from a comparison of the scalograms of the exciter location and the sensor or probe location. From the scalogram comparison, more accurate and reliable physiological parameters may be determined.01-21-2010
20100099993METHODS AND APPARATUS FOR DETERMINING CARDIAC OUTPUT AND LEFT ATRIAL PRESSURE - Method and apparatus are introduced for determining proportional cardiac output (CO), absolute left atrial pressure (LAP), and/or other important hemodynamic variables from a contour of a circulatory pressure waveform or related signal. Certain embodiments of the invention provided herein include the mathematical analysis of a pulmonary artery pressure (PAP) waveform or a right ventricular pressure (RVP) waveform in order to determine beat-to-beat or time-averaged proportional CO, proportional pulmonary vascular resistance (PVR), and/or LAP. The invention permits continuous and automatic monitoring of critical hemodynamic variables with a level of invasiveness suitable for routine clinical application. The invention may be utilized, for example, to continuously monitor critically ill patients with pulmonary artery catheters installed and chronically monitor heart failure patients instrumented with implanted devices for measuring RVP.04-22-2010
20090209868Adaptive Frequency Domain Filtering for Improved Non-Invasive Blood Pressure Estimation - A system for processing oscillometric data from a plurality of pressure steps to determine the blood pressure of a patient as disclosed herein. A heart rate monitor connected to the patient acquires the patient's heart rate. A time to frequency domain converter receives oscillometric data and converts the oscillometric data into the frequency domain. A harmonic frequency calculator is connected to the heart rate monitor and derives at least the heart rate fundamental frequency. A filter connected to the time to frequency domain converter and the harmonic frequency calculator that produces a filter frequency domain oscillometric signal. A reconstruction calculator receives the filtered frequency domain oscillometric signal and reconstructs a time domain oscillometric signal. A method of computing an oscillometric envelope for use in determining the blood pressure of a patient is also disclosed herein.08-20-2009
20090030328METHOD OF ESTIMATING PULSE WAVE VELOCITY - A method of estimating blood pressure Pulse Wave Velocity (PWV) in the aorta from a recording of a pressure waveform at a single site. The method comprises the following steps: 1. measuring the patient's arterial pressure relative to time in order to estimate a central pressure waveform (CPW); 2. estimating the patient's aortic pressure pulse transit time (PPTT) from the CPW; 3. estimating the patient's carotid to femoral arterial distance from the patient's physical characteristics; and 4. dividing the patient's estimated carotid to femoral arterial distance by the patient's estimated PPTT to estimate the patient's PWV.01-29-2009
20110021930SUPPORT DEVICE FOR SENSORS AND/OR ACTUATORS THAT CAN BE PART OF A WIRELESS NETWORK OF SENSORS/ACTUATORS - A support device for sensors and/or actuators, of a node element or End Device (01-27-2011
20090216132System for Continuous Blood Pressure Monitoring - The invention provides a system and method for monitoring blood pressure. The system includes a cuff-free non-invasive portable blood pressure monitoring device, a processor configured to process in real-time signals obtained by the portable blood pressure device to produce one or more processing products, and a portable monitor having a display displaying in real-time one or more of the processing products. In the method of the invention, a blood pressure signal is obtained from a cuff-free non-invasive portable blood pressure monitoring device. Signals obtained by the portable blood pressure device are processed in real-time to produce one or more processing products that are displayed in real-time on a display of a portable monitor. The method and system of the invention may be used in the management of hypertension.08-27-2009
20110098580Method and System for Treating Hypotension - A system and method for treating hypotension in a mammal including a measuring device for measuring the blood pressure in a blood vessel having a wireless transmitter therein for emitting a signal when the measured blood pressure moves into a predetermined range. The system also includes an injection device fixed on the skin of a mammal, the injection device having a receiver for receiving the signal emitted from the wireless transmitter, a drug reservoir, a conduit for moving drug from the drug reservoir through the skin upon activation, and an activation device that causes the drug to move from the drug reservoir through the conduit and into the mammal upon receiving the signal emitted from the wireless transmitter.04-28-2011
20110098579BLOOD-PRESSURE SENSOR SYSTEM - There is provided a blood-pressure sensor system wherein a blood-pressure sensor including a plurality of structures which induces surface plasmon resonance on a light-receiving plane of a photoelectric conversion element is attached to an outer wall of a blood vessel, in which if the blood-pressure sensor is deformed according to expansion or contraction of the blood vessel, an interval of layout of the structure is changed (widened or narrowed), so that an incident form of light with respect to the structures is changed to cause the output from the photoelectric conversion element to be changed. The output is measured as an open circuit voltage, and index calculation is performed, so that a blood pressure value is measured.04-28-2011
20100268096Method and Apparatus For Non-Invasive Assessment of Hemodynamic and Functional State of the Brain - A method and apparatus for assessment of hemodynamic and functional state of the brain is disclosed. In one embodiment, the method and apparatus includes non-invasive measurement of intracranial pressure, assessment of the brain's electrical activity, and measurement of cerebral blood flow. In some embodiments, the method and apparatus include measuring the volume change in the intracranial vessels with a near-infrared spectroscopy or other optical method, measuring the volume change in the intracranial vessels with rheoencephalography or other electrical method, and measuring the brain's electrical activity using electroencephalography.10-21-2010
20100016735METHOD FOR DETERMINATION OF CARDIAC OUTPUT - A method for determination of cardiac output from a recording of an arterial pressure waveform (01-21-2010
20110166459PIEZOELECTRIC SENSOR FOR MEASURING PRESSURE FLUCTUATIONS - The invention relates to a piezoelectric sensor for the improved measurement of mechanical variables such as force, pressure or measurement variables which are derived there from, particularly a PVDF film sensor having an improved sensitivity and temperature stability of the measurement signal for pressure measurements that vary in time and/or space, and for the one- and two-dimensional determination of the position and propagation velocity of pressure fluctuations and pressure waves with a single measurement sensor at a measurement location. A preferred field of application of the invention is the non-invasive, low strain and continuous measurement of the pulse rate and the systolic and diastolic blood pressure of humans and animals by determining the velocity and the signal form of the pulse waves. The object of the invention is to allow the measurements of the blood pressure and the pulse rate, for example even in the case of emergency patients having only a very low blood pressure and patients having circulatory disorders in the extremities, for example patients which have developed diabetes or the “smoker's leg”, by using only one sensor at a measurement location due to the improved measurement sensitivity of the piezoelectric sensor, with the result that the continuous application of a pressurized jacket for continuously measuring and monitoring the blood pressure is not necessary. The present invention solves this problem in that a plurality of parallel strips of a piezoelectric material (07-07-2011
20080312542MULTI-SENSOR ARRAY FOR MEASURING BLOOD PRESSURE - A sensor for monitoring a patient's blood pressure, the sensor including a housing unit with a back surface and which includes: a pair of electrodes mounted on the back surface; an optical system mounted on the back surface and including at least one light source that emits optical radiation near 570 nm and at least one photodetector; a first amplifier which generates an analog electrical waveform from the electrical signals from the electrodes; a second amplifier that generates an analog optical waveform from the optical signal from the photodetector; analog-to-digital converter circuitry configured to receive the analog electrical waveform and generate a digital electrical waveform therefrom and to receive the analog optical waveform and generate a digital optical waveform therefrom; and a processor programmed to receive the digital electrical and optical waveforms and determine a pulse transit time for the patient which is a measure of a separation in time of a first feature of the digital electrical waveform and a second feature of the digital optical waveform and to use the pulse transit time to determine a blood pressure value for the patient.12-18-2008
20090137912Blood Pressure Measurement Apparatus - A blood pressure measurement apparatus includes: a detector, operable to detect a first pulse, a second pulse prior to the first pulse and a third pulse prior to the second pulse under the same pressure; a first distinguisher, operable to distinguish whether waveforms of the first and second pulses are substantially identical with each other; a second distinguisher, when the waveforms are not substantially identical with each other, operable to distinguish whether parameters of the first, second and third pulses meet a condition corresponding to arrhythmia; a determiner, operable to determine the first and second pulses to be pulse waves when the waveforms are substantially identical with each other, and operable to determine the first, second and third pulses to be pulse waves when the parameters meet the condition; and a calculator, operable to calculate a blood pressure value based on the pulse waves.05-28-2009
20120065526PIEZOELECTRIC SENSOR FOR MEASURING PRESSURE FLUCTUATIONS - The invention relates to a piezoelectric sensor for the improved measurement of mechanical variables such as force, pressure or measurement variables which are derived there from, particularly a PVDF film sensor having an improved sensitivity and temperature stability of the measurement signal for pressure measurements that vary in time and/or space, and for the one- and two-dimensional determination of the position and propagation velocity of pressure fluctuations and pressure waves with a single measurement sensor at a measurement location. A preferred field of application of the invention is the non-invasive, low strain and continuous measurement of the pulse rate and the systolic and diastolic blood pressure of humans and animals by determining the velocity and the signal form of the pulse waves. The object of the invention is to allow the measurements of the blood pressure and the pulse rate, for example even in the case of emergency patients having only a very low blood pressure and patients having circulatory disorders in the extremities, for example patients which have developed diabetes or the “smoker's leg”, by using only one sensor at a measurement location due to the improved measurement sensitivity of the piezoelectric sensor, with the result that the continuous application of a pressurized jacket for continuously measuring and monitoring the blood pressure is not necessary. The present invention solves this problem in that a plurality of parallel strips of a piezoelectric material (03-15-2012
20110092828Fluid Delivery System, Fluid Path Set, and Pressure Isolation Mechanism with Hemodynamic Pressure Dampening Correction - The fluid delivery system includes a pressurizing device for delivering injection fluid under pressure, a low pressure fluid delivery system, and a pressure isolation mechanism. The pressure isolation mechanism includes a first lumen associated with the pressurizing device, a second lumen associated with the low pressure fluid delivery system, and a pressure isolation port. The first valve is in a normally open position permitting fluid communication between the first lumen and the second lumen and movable to a closed position when fluid pressure in the first lumen reaches a predetermined pressure level. The first valve isolates the pressure isolation port from the first lumen in the closed position. A second valve is associated with the second lumen and regulates fluid flow through the second lumen. The second valve may be a disk valve defining one or more passageways in the form of slits through the body of the disk valve.04-21-2011
20110092827BLOOD PRESSURE MONITOR AND METHOD FOR CALCULATING BLOOD PRESSURE THEREOF - A blood pressure monitor and a method for calculating blood pressure thereof are revealed. The blood pressure monitor includes a cuff, an air pump, an air escape valve, a pressure sensor, a processing circuit, and an arithmetic circuit. The cuff is arranged a a body to be detected while and the air pump inflates the cuff and the air escape valve is for releasing air from the cuff. The pressure sensor is disposed on the cuff for detecting cuff pressure to generate analog pressures sensing signals. The processing circuit processes the analog pressure sensing signals and generates digital pressure sensing signals. A slope of each digital pressure sensing signal is calculated by the arithmetic circuit. A pressure value of the digital pressure sensing signal corresponding to a maximum slope is an average blood pressure. Then find a second derivative of each digital pressure sensing signal. A pressure value of the digital pressure sensing signal corresponding to a largest maximum value of the second derivative is systolic pressure while a pressure value of the digital pressure sensing signal corresponding to a smallest minimum value of the second derivative is diastolic pressure.04-21-2011
20100241011Calibration of Pulse Transit Time Measurements to Arterial Blood Pressure using External Arterial Pressure Applied along the Pulse Transit Path - An apparatus and methods for adaptive and autonomous calibration of pulse transit time measurements to obtain arterial blood pressure using arterial pressure variation. The apparatus and methods give pulse transit time (PTT) devices an ability to self-calibrate. The methods apply a distributed model with lumped parameters, and may be implemented, for example, using pulse transit time measurements derived from a wearable photoplethysmograph (PPG) sensor architecture with an intervening pressurizing mechanism.09-23-2010
20110066045BODY-WORN VITAL SIGN MONITOR - The invention provides a body-worn monitor featuring a processing system that receives a digital data stream from an ECG system. A cable houses the ECG system at one terminal end, and plugs into the processing system, which is worn on the patient's wrist like a conventional wristwatch. The ECG system features: i) a connecting portion connected to multiple electrodes worn by the patient; ii) a differential amplifier that receives electrical signals from each electrode and process them to generate an analog ECG waveform; iii) an analog-to-digital converter that converts the analog ECG waveform into a digital ECG waveform; and iv) a transceiver that transmits a digital data stream representing the digital ECG waveform (or information calculated from the waveform) through the cable and to the processing system. Different ECG systems, typically featuring three, five, or twelve electrodes, can be interchanged with one another.03-17-2011
20110066044BODY-WORN VITAL SIGN MONITOR - The invention provides a body-worn monitor featuring a processing system that receives a digital data stream from an ECG system. A cable houses the ECG system at one terminal end, and plugs into the processing system, which is worn on the patient's wrist like a conventional wristwatch. The ECG system features: i) a connecting portion connected to multiple electrodes worn by the patient; ii) a differential amplifier that receives electrical signals from each electrode and process them to generate an analog ECG waveform; iii) an analog-to-digital converter that converts the analog ECG waveform into a digital ECG waveform; and iv) a transceiver that transmits a digital data stream representing the digital ECG waveform (or information calculated from the waveform) through the cable and to the processing system. Different ECG systems, typically featuring three, five, or twelve electrodes, can be interchanged with one another.03-17-2011
20110066043SYSTEM FOR MEASURING VITAL SIGNS DURING HEMODIALYSIS - The invention provides a system for continuously monitoring a patient during hemodialysis. The system includes a hemodialysis machine for performing the hemodialysis process that features a controller, a pump, a dialyzer filter, a lumen, and an interface to a body-worn monitor. A patient attaches to the dialysis machine through the lumen, and wears a body-worn monitor for continuously measuring blood pressure. The monitor includes an optical system for measuring an optical waveform, an electrical system for measuring an electrical waveform, and a processing component for determining a transit time between the optical and electrical waveforms and then calculating a blood pressure value from the transit time. The body-worn monitor features an interface (e.g. a wired serial interface, or a wireless interface) to transmit the blood pressure value to the controller within the hemodialysis machine. The controller is configured to receive the blood pressure value, analyze it, and in response adjust the dialysis process.03-17-2011
20110105916Diagnostic method and apparatus - An electrical interferential device comprises a circuit for delivering electrical interferential energy into the body of a patient. A sensor detects a function of the autonomic nervous system of the patient and provides an output indicative of the response of the autonomic nervous system to the electrical interferential energy. A treatment regimen is selected which uses a combination of carrier and beat frequencies and electrode placement pattern that produce a desired response in the autonomic nervous system of the patient. In one embodiment of the invention, a diagnostic tool is used to determine which combination of carrier and beat frequencies are desirable and treatment is provided by a second electrical interferential device. In another embodiment of the invention, the same diagnostic tool or a portion of the same diagnostic tool may be used to treat the patient.05-05-2011
20100094142Display Module of LED Light Pillar of Hemomanometer and the Hemomanometer with LED Light Pillar - The present invention relates to an instrument for measuring blood pressure. More particularly, the present invention relates to a display module of LED light pillar of hemomanometer. Which comprises a shell (04-15-2010
20100094141JUGULAR VENOUS PRESSURE RULER - A JVP ruler and a method for its use in measuring a jugular venous pressure in a patient, includes orienting the JVP ruler such that the second arm is collinear with a vertical line originating at a right atrium of the patient and such a the first arm is horizontal and having a transducer end situated opposite the pivot end of the first arm. The JVP Ruler has first and second arms elongate and situated to be in perpendicular relation one to the other. The arms meet and terminate at a pivot located at the pivot ends of the arms respectively, the transducer end being generally above a pulse point, the pulse point being a point on the skin of the patient where variations of the jugular venous pressure within the internal jugular vein are exhibited as at least vertical displacement of the skin.04-15-2010
20120165686BLOOD VESSEL FUNCTION INSPECTING APPARATUS - It is provided a blood vessel function inspecting apparatus including: a blood vessel diameter measuring portion configured to measure a diameter of a blood vessel; a blood vessel wall thickness measuring portion configured to measure a wall thickness of the blood vessel; and a blood vessel function index value calculating portion configured to calculate a function index value for diagnosing the blood vessel of its function, after releasing of the blood vessel from blood flow obstruction, by dividing an amount of dilatation of said diameter of the blood vessel continuously measured by said blood vessel diameter measuring portion, by the wall thickness measured by said blood vessel wall thickness measuring portion.06-28-2012
20120165685PLASMAPHERESIS DONOR DISPLAY AND METHOD OF USE - Certain examples provide a blood collection system including an operator user interface to allow an operator to configure the system for a blood collection procedure from a donor. The system also includes a donor display, separate from the operator user interface, arranged in the system to be within view of the donor who is to donate via the system. The donor display is to display information and instruction to the donor. The information and instruction include a first indicator regarding a progress of the blood collection procedure for the donor and a second indicator including a visual instruction to the donor regarding the blood collection procedure. The system includes a processor and a memory. The processor is to execute instructions stored in the memory to process input from and provide output to the operator user interface and the donor display.06-28-2012
20120123280METHOD FOR MEASURING ARTERIAL PRESSURE AND A DEVICE FOR THE IMPLEMENTATION OF SAME - A method for measuring arterial pressure involves hydraulically separating a static pressure source from a body area situated opposite thereto and containing an artery by placing a rigid separating element between the two and along the artery. With the aid of the separating element, pulse waves are converted into pressure waves, which run along said element on the first side thereof, and the passage of the pulse waves is detected with the aid of the pressure waves. A device for measuring arterial pressure comprises a rigid separating element which has a first contact surface for interacting with the body and a second contact surface which is opposite to the first and is used for interacting with the static pressure source. A push-type pressure gauge with a contact area that is embedded into one of the two contact surfaces of the separating element and a pulse wave detector are disposed inside the rigid separating element. The sensing element of the detector is located on the first contact surface.05-17-2012
20090131806Apparatus and methods for non-invasively measuring a patient's arterial blood pressure - Improved apparatus and methods for non-invasively assessing one or more hemodynamic parameters associated with the circulatory system of a living organism. In one aspect, the invention comprises an apparatus adapted to automatically and accurately place and maintain a sensor (e.g., tonometric pressure sensor) with respect to the anatomy of the subject. The apparatus comprised of a sensor device removably coupled to an actuator which is used to position the sensor during measurements. Methods for positioning the alignment apparatus and sensor, and operating the apparatus, are also disclosed.05-21-2009
20090131805Patient Monitoring - A hemodynamic monitor and corresponding method for determining the requirement for, and if required the nature or extent of, and for monitoring the response to, an intervention by a carer for a subject in order to improve the hydration level and hemodynamic status of the subject during a period or periods of hemodynamic instability includes, firstly, a processor. The processor incorporates software arranged to continuously analyse and process a blood pressure or arterial volume/plethysmographic signal obtained from the subject in order to derive a plurality of complementary parameters throughout the monitoring of the subject. The monitor also incorporates display means displaying images representing the derived plurality of complementary parameters. The images may include at least one image representing graphically at least one stress related hemodynamic parameter plotted against time to provide an immediate indication of a change in hemodynamic status and thus the requirement for an intervention. The images may also include at least one image representing graphically at least one fluid responsiveness parameter plotted against time to provide an indication of the hydration level and associated ventricular pre load status of the subject to determine the nature or extent of the intervention if required. Respiratory variations in fluid responsiveness parameters may usefully be displayed. The images may also include at least one image representing graphically at least one response related parameter compared to the value of the parameter at the point of the intervention to provide an indication of the desired and/or actual response of the subject to an intervention. Trend and acute changes displays may be combined. Specific parameters providing information on the quality of the left ventricle and right heart/venous return/preload may also be derived and displayed.05-21-2009
20090131804Method And Apparatus For Determining Central Aortic Pressure Waveform - A method is provided for determining a central aortic pressure waveform. The method includes: measuring two or more peripheral artery pressure waveforms; analyzing the signals so as to extract common features in the measured waveforms; and determining an absolute central aortic pressure waveform based on the common features.05-21-2009
20120220882Device for the Non-Invasive Determination of Arterial Blood Pressure08-30-2012
20120136261Systems and methods for calibrating physiological signals with multiple techniques - Systems and methods are disclosed herein for calibrating the calculation of physiological parameters. Two or more calibration techniques may be used to determine a relationship between physiological measurements and a desired physiological parameter, such as a relationship between differential pulse transit time (DPTT) and blood pressure. Different calibration techniques may be used in a serial fashion, one after the other, or in a parallel fashion, with different weights accorded to each calibration technique. When physiological or other changes occur, the calibration data may be stored for later use and new calibration data may be generated.05-31-2012
20100049059APPARATUS AND METHOD FOR MEASURING BLOOD PRESSURE - Disclosed are blood pressure measuring apparatus and method, in which a blood pressure measuring posture of a person to be examined is calculated on the basis of signals that are measured by an inclination measuring unit, so as to guide the person to be examined to maintain a reference measuring posture. When it is confirmed that the person to be examined maintains the reference measuring posture, blood pressure is measured on the basis of a measured living body signal of the person to be examined. By this disclosure, since the blood pressure measuring posture of the person to be examined can be correctly guided by inclination sensors, the person to be examined can accurately measure the blood pressure using a noninvasive and a nonpressurized method.02-25-2010
20100298719METHOD FOR CALCULATING PRESSURES IN A FLUID STREAM THROUGH A TUBE SECTION, ESPECIALLY A BLOOD VESSEL WITH ATHEROSCLEROTIC PLAQUE - A method for calculating pressures in a fluid streaming through a tube section from an upstream end to a downstream end of the tube section, the method comprising scanning the tube section with a scanner and providing a plurality of 2D scanning images along the tube section with an inlet and at least two arms, by a computer program on the basis of the 2D images automatically N calculating a 3D image of the tube section by using interpolating between the 2D images, by a computer program performing a 2D sectional image cut through the 3D image, the image cut following the fluid stream, calculating in the sectional image cut a fluid pressure distribution along multiple locations inside the tube on the basis of given boundary conditions, the boundary conditions including fluid velocity or fluid pressure at the upstream end.11-25-2010
20120179053APPARATUS FOR MEASURING A PROPAGATION VELOCITY OF A BLOOD PRESSURE WAVE - An apparatus for measuring the propagation velocity of a pressure wave comprises a first sensor of cutaneous vibration to measure a vibration generated in a first application point, creating a corresponding first signal, and a second sensor of cutaneous vibrations to measure a local cutaneous vibration generated in second point of an arterial vessel, creating a corresponding second signal caused by the deformation of the vessel responsive to the progression of the pressure wave in the vessel. A control unit detects on the first and second signal respectively a first instant time T07-12-2012
20090069699Method of measuring instantaneous arterial blood pressure and compliance and device thereof - A method of measuring the instantaneous arterial blood pressure and compliance and the device thereof are disclosed. The method identifies a critical depth under the skin. At this critical position, the arterial mean blood pressure is equivalent to the mean blood pressure obtained on the skin. The variation in the arterial mean blood pressure is tracked and controlled to maintain the equivalence between the mean blood pressure measured on the skin and the arterial mean blood pressure. In this case, the compliance of the muscle tissues remains invariant. Therefore, the variation measured on the skin is simply the behavior of the blood vessel. Using the skin-artery correlation, the invention can obtain the instantaneous blood pressure after some computation and the dynamic compliance at the critical position.03-12-2009
20120259235Systems and Methods for Monitoring Heart Rate and Blood Pressure Correlation - Systems and methods are provided for monitoring a correlation between heart rate and blood pressure in a patient. When a characteristic of the correlation exceeds a threshold, a patient status indicator signal is sent to a monitoring device. In some embodiments, the patient status indicator signal indicates a particular medical condition or alerts a care provider to a change in status. In some embodiments, the heart rate signal is used to improve a blood pressure estimate generated by a different signal. In some embodiments, the heart rate, blood pressure and correlation signals are used in a predictive mathematical model to estimate patient status or outcome.10-11-2012
20120190991System and Method for Detecting a Clinically-Significant Pulmonary Fluid Accumulation Using an Implantable Medical Device - Techniques are provided for detecting a clinically-significant pulmonary fluid accumulation within a patient using a pacemaker or other implantable medical device. Briefly, the device detects left atrial pressure (LAP) within the patient and tracks changes in the LAP values over time that are indicative of possible pulmonary fluid accumulation within the patient. The device determines whether the changes in LAP values are sufficiently elevated and prolonged to warrant clinical intervention using, e.g., a predictor model-based technique. If the fluid accumulation is clinically significant, the device then generates warning signals, records diagnostics, controls therapy and/or titrates diuretics. False positive detections of pulmonary edema due to transients in LAP are avoided with this technique. Pulmonary artery pressure (PAP)-based techniques are also described.07-26-2012
20120232411PRESSURE MEASURING SYSTEM, PRESSURE MEASURING SENSOR ASSEMBLY AND A METHOD OF MEASURING A PRESSURE - A pressure measuring System (09-13-2012
20110009754ARTERIAL BLOOD PRESSURE MONITORING DEVICES, SYSTEMS AND METHODS USING CARDIOGENIC IMPEDANCE SIGNAL - Provided herein are implantable systems, and methods for use therewith, for monitoring a patient's arterial blood pressure. Electrode(s) implanting within and/or on the patient's heart are used to obtain a cardiogenic impedance (CI) signal indicative of cardiac contractile activity. Additionally, a signal (e.g., PPG or IPG signal) indicative of changes in arterial blood volume remote from the patient's heart is obtained using a sensor or electrodes that are implanted remote from the patient's heart. One or more metrics indicative of pulse arrival time (PAT) are determined, where each metric can be determined by determining a time from one of the detected features of the CI signal to one of the detected features of the signal indicative of changes in arterial blood volume. Based on at least one of the metric(s) indicative of PAT, arterial blood pressure is estimated, which can include determining values indicative of systolic blood pressure, diastolic blood pressure, pulse pressure and/or mean arterial blood pressure, and/or changes in such values.01-13-2011
20110046493SYSTEM AND METHOD FOR GENERATING BASELINE DATA FOR AUTOMATED MANAGEMENT OF CARDIOVASCULAR PRESSURE - A system and method for generating baseline data for automated management of cardiovascular pressure is disclosed. Collected device measures are accumulated to record raw physiometry for a patient, wherein the patient is regularly monitored by an implantable medical device, beginning with an initial observation period. Derived device measures are generated to provide derivative physiometry determined at least in part from the collected device measures. A patient status indicator is determined by analyzing the collected and derived device measures to diagnose a pathophysiology indicative of an absence, onset, progression, regression, and status quo in cardiovascular pressure, wherein the collected and derived device measures and the patient status indicator originating from the initial observation period include baseline data.02-24-2011
20110046492MONITORING FOR MITRAL VALVE REGURGITATION - Implantable systems, and methods for use therein, for monitoring for mitral valve regurgitation (MR) are provided. An electrogram (EGM) signal and a corresponding pressure signal are obtained, where the EGM signal is representative of electrical functioning of the patient's heart during a plurality of cardiac cycles, and the corresponding pressure signal is representative of pressure within the left atrium the patient's heart during the cardiac cycles. Windows of the pressure signal are defined, based on events detected in the EGM signal, and measurements from the windows are used to monitor for MR.02-24-2011
20110213254METHOD OF DETERMINING BLOOD PRESSURE AND AN APPARATUS FOR DETERMINING BLOOD PRESSURE - An apparatus and method enables a reading of a continuous beat to beat heart rate at the superficial temporal artery to give an indication of blood pressure of the brain and blood related diseases. The apparatus is non-invasive. Preferably a reading of a continuous beat to beat heart rate is measured on both the left superficial temporal artery and the right superficial temporal artery simultaneously during the same heart beat. Where the wave form measured from the left temporal artery differs from the wave form measured from the right temporal artery this may be an indication of an impending stroke or an indication that a stroke has recently happened. Further, the indices of the wave forms may be used as a clinical indication of other blood related diseases.09-01-2011
20100249613MASSAGE APPARATUS AND MASSAGE PROGRAM - A massage apparatus includes: a massage unit configured to massage a user; a biological information acquisition unit configured to acquire biological information of the user; a stress estimation unit configured to estimate a degree of stress of the user based on the biological information acquired by the biological information acquisition unit; and an operation determination unit configured to determine a massage operation to be performed for the user by the massage unit based on the degree of stress of the user estimated by the stress estimation unit.09-30-2010
20100179439DEVICE AND METHOD FOR CORRECTING A BLOOD PRESSURE MEASURED - A device for altitude correction of a blood pressure measured at a measuring position of a living being has a transmitter, at least three receivers and an evaluating unit. The transmitter emits a signal from close to a measuring position and the at least three receivers receive the signal, wherein the receivers may be mounted to positions at different altitudes of the living being. The evaluating unit corrects the blood pressure measured on the basis of run time or phase differences of the signals received at the at least three receivers.07-15-2010
20100130874Apparatus and method for determining a physiologic parameter - An apparatus for determining physiologic parameters of a patient (05-27-2010
20110137184PRESSURE SENSING - A high electron mobility transistor (HEMT) is disclosed capable of performing as a pressure sensor. In one embodiment, the subject pressure sensor can be used for the detection of body fluid pressure. A piezoelectric, biocompatible film can be used to provide a pressure sensing functionalized gate surface for the HEMT. Embodiments of the disclosed sensor can be integrated with a wireless transmitter for constant pressure monitoring.06-09-2011
20080243006METHOD AND APPARATUS FOR CONTINUOUS PULSE CONTOUR CARDIAC OUTPUT - A system and method are provided for sensing cardiac electrogram (EGM) signals and ventricular pressure signals and for using the sensed EGM and sensed pressure signals for estimating stroke volume (SV). A measure of cardiac output can be computed from the estimated SV and a heart rate determined from the EGM signals. The sensed ventricular pressure signal and the sensed EGM signal are used to derive landmark points such as an estimated pulmonary diastolic pressure, a mean pulmonary artery pressure, a peak right ventricular pressure (RVP), and various time intervals used in computing an area or a pulse contour integral. The pulse contour integral is used to estimate SV. The estimated pulmonary diastolic pressure, mean pulmonary artery pressure and CO computed from the estimated SV can be used to compute a pulmonary vascular resistance.10-02-2008
20080228089 Method and apparatus for cufflessly and non-invasively measuring wrist blood pressure in association with communication device - A method of cufflessly and non-invasively measuring blood pressure in a wrist region of a patient in association with a communication device that relays the information being measured includes: detecting a magnitude difference between a plurality of pulse wave signals detected from a wrist of a user; detecting feature points from an electrocardiogram (ECG) and pulse wave signals detected from the user; extracting variables needed to calculate the highest blood pressure and the lowest blood pressure using the detected feature points; and calculating the highest blood pressure and the lowest blood pressure of the user by deducing a scatter diagram using the extracted variables.09-18-2008
20080228088System and Method for Detecting and Predicting a Syncope Event - The present invention relates to a system (09-18-2008
20080228087PRESSURE MEASUREMENT DEVICE - A pressure measurement device isolates liquid, such as blood, from an intermediate fluid, such as air, by means of a diaphragm. The diaphragm is arranged between first and second chambers of respective first and second shells of a pressure pod body. The first shell has first and second ports, which are connected to the first chamber. The second shell has a measurement port with a connector in communication with the second chamber. A pressure transducer with a mating connector is directly connected to the measurement port connector to minimize the sealed volume between the diaphragm and the pressure transducer.09-18-2008
20130172761METHOD, APPARATUS AND PROGRAM FOR THE AUTOMATIC PROCESSING OF BLOOD PRESSURE SIGNALS - The invention concerns an automated method, a system and means for processing the blood pressure from a detected pressure signal, the method operating in the time domain to determine a value (RES) connected to the energy efficiency of the monitored biological system.07-04-2013
20080221462Detection of oximetry sensor sites based on waveform characteristics - In accordance with an embodiment of the present technique, there is provided methods and systems for detecting the location of a sensor and determining calibration algorithms and/or coefficients for calculation of physiological parameters based on the detected location. An exemplary embodiment includes receiving a signal corresponding to absorption of at least one wavelength of light by a patient's tissue, generating a plethysmographic waveform from the signal, determining an identifying characteristic of the plethysmographic waveform, and determining a location of the sensor based on a comparison of the identifying characteristic with at least one defined criterion.09-11-2008
20080221461VITAL SIGN MONITOR FOR CUFFLESSLY MEASURING BLOOD PRESSURE WITHOUT USING AN EXTERNAL CALIBRATION - The invention provides a method for measuring a patient's blood pressure featuring the following steps: 1) measuring a first time-dependent optical signal with a first optical sensor; 2) measuring a second time-dependent optical signal with a second optical sensor; 3) measuring a time-dependent electrical signal with an electrical sensor; 4) estimating the patient's arterial properties using either the first or second time-dependent optical signal; 5) determining a pulse transit time (PTT) from the time-dependent electrical signal and at least one of the first and second time-dependent optical signals; and 6) calculating a blood pressure value using a mathematical model that includes the PTT and the patient's arterial properties.09-11-2008
20130096444SYSTEM AND METHOD FOR DYNAMICALLY ADJUSTING PATIENT THERAPY - A system and method of managing therapy provided to patients in an institution. The system monitors all aspects of the medication delivery to a patient, as well as other information related to the patient, such as values of vital signs, laboratory results and patient factors such as history, diagnosis, allergies and the like. The system includes one or more databases of information, including institutionally developed rules, guidelines and protocol representing the best medical practices of the institution. The system provides alerts and/or recommendations based on the application of the rules to the information being monitored, and alerts care givers accordingly, providing for dynamic adjustment of the patient's therapy. The system also monitors the status of the alerts, and if no action is taken in a selected period of time, may escalate the priority of the alert and/or halt the delivery of medication to the patient until the alert is resolved.04-18-2013
20130096443PUSH-TYPE DISCHARGE ASSEMBLY OF BLOOD PRESSURE MONITOR - A push-type discharge assembly of a blood pressure monitor includes a valve base, a spring, a driven element, a restricting element, and a pressing element. The valve base is provided with an accommodating trough and an intake pipe. The spring is disposed in the accommodating trough. The driven element abuts against one end of the spring. The driven element is formed with a protrusion. The restricting element covers the accommodating trough. The restricting element has a central through-hole and is formed with a restricting notch. The pressing element passes through the central through-hole. The pressing element has a sealing body and a driving portion disposed on a lower edge of the sealing body to drive the driven element. When the pressing element is pressed downwards, the sealing body moves downwards to form a discharge channel between the pressing element and the central through-hole.04-18-2013
20130102909METHOD AND APPARATUS FOR DETERMINING A CENTRAL AORTIC PRESSURE WAVEFORM - A method is provided for determining a central aortic pressure waveform. The method includes: measuring two or more peripheral artery pressure waveforms; analyzing the signals so as to extract common features in the measured waveforms; and determining an absolute central aortic pressure waveform based on the common features.04-25-2013
20130144175PERSONAL HEALTH INFORMATION IDENTIFICATION TAG - A smart identification tag system comprises a helmet and an identification tag. The helmet defines a headspace adapted to receive a wearer's head. A sensor assembly is disposed in the headspace and comprises a sensor capable of capturing data and a wireless transceiver in communication with the sensor and adapted to transmit a wireless signal indicative of data captured by the sensor. The identification tag comprises a wireless transceiver adapted to receive the signal from the helmet, and a non-transitory memory in communication with the wireless transceiver and adapted to store the received data. The helmet is adapted to be worn by a wearer, and the identification tag is adapted to be carried on the person of the wearer, such that information captured by the sensor assembly is transmitted to the identification tag and stored therein. The identification tag may further store personal health information of the wearer.06-06-2013
20080200820System for determining endothelial dependent vasoactivity - A method of determining endothelial dependent vasoactivity of a subject, the method is effected by recording pressure-related signals of a plurality of locations adjacent to at least one blood vessel; extracting at least one parameter from the pressure-related signals; and using the at least one parameter to determine a change of at least one characteristic of the at least one blood vessel, the change being representative of endothelial functioning; thereby determining the endothelial dependent vasoactivity of the subject.08-21-2008
20110224557BODY-WORN VITAL SIGN MONITOR - The invention provides a body-worn vital sign monitor that measures a patient's vital signs (e.g. blood pressure, SpO2, heart rate, respiratory rate, and temperature) while simultaneously characterizing their activity state (e.g. resting, walking, convulsing, falling) and posture (upright, supine). The monitor processes this information to minimize corruption of the vital signs and associated alarms/alerts by motion-related artifacts. It also features a graphical user interface (GUI) rendered on a touchpanel display that facilitates a number of features to simplify and improve patient monitoring and safety in both the hospital and home.09-15-2011
20110230772METHOD AND DEVICE FOR INVASIVE BLOOD PRESSURE MEASUREMENT IN A VASCULAR ACCESS - A device and method for invasive blood pressure measurement in a vascular access under continuous blood flows in a treatment device in extracorporeal detoxification methods is provided. Systemic arterial pressure is directly measured using an existing vascular access for dialysis, or in which the systemic arterial pressure and the temporal progression of such pressure are determined indirectly. A valve-controlled bypass system which goes around a blood pumping unit is provided so that the blood flow in the treatment device is not interrupted, and alarms are suppressed The bypass module is easily connectable to measuring equipment on various treatment units without having to adjust the same.09-22-2011
20100286535MEDICAL DEVICE FOR DETECTING PULMONARY ARTERY PRESSURE - In a medical device and method to monitor pulmonary artery pressure of a patient, a first parameter related to the right ventricular straight volume of the patient's is detected, and a second parameter related to the right ventricular ejection rate of the patient's heart, or related to the workload of the patient's heart, is also determined. A pulmonary pressure index is determined by combining the first and second parameters, with variations of the pulmonary pressure index indicating variations in the pulmonary artery pressure. Pulmonary artery hypertension can be monitored with such a device and method.11-11-2010
20110275943Arterial Pressure-Based, Automatic Determination of a Cardiovascular Parameter - One or more cardiovascular parameters is estimated as a function of the arterial pressure waveform, in particular, using at least one statistical moment of a discrete representation pressure waveform having an order greater than one. Arterial compliance, the exponential pressure decay constant, vascular resistance, cardiac output, and stroke volume are examples of cardiovascular parameters that can be estimated using various aspects of the invention. In one embodiment of the invention, not only are the first four moments (mean, standard deviation, skewness, and kurtosis) of the pressure waveform used to estimate the cardiovascular parameter(s) of interest, but also heart rate, statistical moments of a set of pressure-weighted time values, and certain anthropometric patient measurements such as age, sex, body surface area, etc.11-10-2011
20110237961METHODS AND APPARATUS FOR CONTROL OF NON-INVASIVE PARAMETER MEASUREMENTS - Improved methods and apparatus for non-invasively assessing one or more parameters associated with fluidic systems such as the circulatory system of a living organism. In a first aspect, an improved method of continuously measuring pressure from a compressible vessel is disclosed, wherein a substantially optimal level of compression for the vessel is achieved and maintained using perturbations (e.g., modulation) of the compression level of the vessel. In one exemplary embodiment, the modulation is conducted according to a pseudo-random binary sequence (PBRS). In a second aspect, an improved apparatus for determining the blood pressure of a living subject is disclosed, the apparatus generally comprising a pressure sensor and associated processor with a computer program defining a plurality of operating states related to the sensed pressure data. Methods for pressure waveform correction and reacquisition, as well as treatment using the present invention, are also disclosed.09-29-2011
20110237960METHOD, SYSTEM AND APPARATUS FOR MONITORING PATIENTS - A method, system and apparatus are disclosed for monitoring a subject with a transport monitor comprising a measurement unit including at least one magnetic component unit operative when monitoring the subject in absence of a high magnetic field. To maintain the monitoring capacity of a standard transport monitor even in the high magnetic field, the transport monitor is provided with a reconfiguration unit adapted to reconfigure the measurement unit for the high magnetic field so that at least part of the monitoring capability that the measurement unit has in absence of the high magnetic field is preserved in presence of the high magnetic field.09-29-2011
20130150735METHOD AND DEVICE FOR MEASURING PARAMETERS OF CARDIAC FUNCTION - A device for non-invasively measuring at least one parameter of a cardiac blood vessel in a patient is provided. The device comprises at least one light source that emits light in the 400 nm to 1000 nm wavelength range; at least one photodetector adapted to receive light emitted by the light source and generate an output based on the received light, wherein said light is reflected from or transmitted through tissue of the patient, the output of said photodetector being correlated with a parameter of the blood vessel; and at least one probe for facilitating delivery of light from the light source to an external tissue site on the patient in the proximity of the cardiac blood vessel and receipt of light by the photodetector. A system and methods of monitoring/measuring cardiac parameters utilizing the device and/or system are also provided.06-13-2013
20130150736AUTOMATIC METHOD FOR MEASURING AND PROCESSING BLOOD PRESSURE - The present invention concerns an automatic method, as well as the related system and the tools allowing the same to be executed, for measuring and processing blood pressure starting from a detected pressure signal, the method operating in the time domain for discriminating whether the detected signal is an adequate measurement or not and, where it is not, time domain analysis automatically selects a low-pass filter to, possibly iteratively, apply to the detected pressure signal for having correct values and wave form of the blood pressure.06-13-2013
20100298720In Situ Energy Harvesting Systems for Implanted Medical Devices - This invention concerns miniature implantable power sources that harvest or scavenge energy from the expansion and contraction of biological tissues, for example, an artery or a bundle of muscle fiber. Such power sources employ an energy harvesting element that converts mechanical or thermal energy existing or generated in or from a pulsatile tissue into a form of electrical energy that can be used or stored by an implanted medical device, such as a blood pressure sensor, a flow meter, or the like. Preferred energy harvesting element embodiments utilize a piezoelectric thin film embedded within a flexible, self-curling medical-grade polymer or coating. Such power sources can be used to produce self-powered implanted microsystems with continuous or near-continuous operation, increased lifetimes, reduced need for surgical replacement, and minimized or eliminated external interface requirements.11-25-2010
20100317976DEVICE AND PROCESS FOR CALCULATING NEW INDICES OF ARTERIAL STIFFNESS, AND/OR FOR STROKE VOLUME MONITORING - A process for calculating an indice of arterial stiffness, including the step of extracting pulse wave analysis data from a recorded pressure of an artery, the recorded pressure is recorded as a function of time, the indice being calculated as a function of the extracted data, and the extracted pulse wave analysis data including at least one time interval.12-16-2010
20120283582SYSTEMS AND METHODS FOR DETERMINING LOCATION OF AN ACCESS NEEDLE IN A SUBJECT - Systems and methods for epicardial electrophysiology and other procedures are provided in which the location of an access needle may be inferred according to the detection of different pressure frequencies in separate organs, or different locations, in the body of a subject. Methods may include inserting a needle including a first sensor into a body of a subject, and receiving pressure frequency information from the first sensor. A second sensor may be used to provide cardiac waveform information of the subject. A current location of the needle may be distinguished from another location based on an algorithm including the pressure frequency information and the cardiac waveform information.11-08-2012
20120283581DEVICES, A COMPUTER PROGRAM PRODUCT AND A METHOD FOR DATA EXTRACTION - A monitoring device receives a measurement signal obtained by a pressure sensor in an extracorporeal fluid system, such as an extracorporeal blood circuit for a dialysis machine which is in contact with a vascular system of a subject via a fluid connection. The monitoring device processes the measurement signal to identify pressure data that represents pulses originating from a first physiological phenomenon in the subject, excluding the heart of the subject. The first physiological phenomenon may be any of reflexes, voluntary muscle contractions, non-voluntary muscle contractions, a breathing system of the subject, an autonomous system of the subject for blood pressure regulation, or an autonomous system of the subject for body temperature regulation. The monitoring device may detect, present, track or predict a disordered condition of the subject using the pressure data, or monitor the integrity of the fluid connection based on the pressure data.11-08-2012
20120283580VERIFICATION OF PRESSURE METRICS - An example system may include at least one pressure sensor configured to measure a cardiovascular pressure signal and another medical device configured to measure an electrical depolarization signal of the heart. The system determines a plurality of cardiovascular pressure metrics based on the measured cardiovascular pressure signal, including at least one cardiovascular pressure metric indicative of a timing of at least one cardiac pulse. The system also determines a metric indicative of a timing of at least one heart depolarization within the measured electrical depolarization signal. The system compares the timing of the at least one cardiac pulse to the timing of the at least one depolarization, and determines whether to discard the plurality of cardiovascular pressure metrics based on whether the timings substantially agree.11-08-2012
20130158417METHOD, APPARATUS AND COMPUTER PROGRAM FOR AUTOMATIC NON-INVASIVE BLOOD PRESSURE MEASUREMENT - A method, apparatus and computer program product are disclosed for non-invasively determining blood pressure of a subject. To improve the specificity of automatic blood pressure determinations in a patient monitor provided with a non-invasive blood pressure determination unit, a physiological index indicative of sympathetic activity is derived from a subject, variations in the physiological index are monitored, and the blood pressure determination unit is instructed to initiate blood pressure determination when the variations fulfill a predetermined condition.06-20-2013
20130184595METHODS AND APPARATUS FOR DETERMINING ARTERIAL PULSE WAVE VELOCITY - Methods are presented for determining pulse transit time (PTT) and/or pulse wave velocity (PWV) of a subject by application of parametric system identification to proximal and distal arterial waveforms. The two waveforms are measured from the subject. A system is defined that relates the proximal arterial waveform to the distal arterial waveform (or vice versa) in terms of the unknown parameters of a parametric mathematical model. The model parameters are determined from the measured waveforms using system identification. PTT between the proximal and distal arterial sites is then determined from the system model. PWV may also be determined by dividing the distance between measurement sites (D) by PTT.07-18-2013
20110313301BLOOD PRESSURE IRREGULARITY SENSING - A medical device obtains a set of data associated with a patient's non-invasive blood pressure cycle reading, provides a representation of a pulse interval map on the display screen based on the set of data, the pulse interval map including one or more interval data points representing intervals between heat beats, and alerts a caregiver if one or more of the interval data points fall outside an interval bound. The medical device can also plot a pulse volume map on the display screen based on the set of data, the pulse volume map including one more volume data points representing volumes associated with given heat beats, and alert a caregiver if one or more of the volume data points fall outside a volume bound.12-22-2011
20110313300DETECTION OF NOISE DURING HEART BEAT VARIATION EVALUATION - A medical device obtains an oscillometric measurement associated with a patient's non-invasive blood pressure reading. The device determines a stability measure for at least one pair of pulses included in the oscillometric measurement, compares the stability measure to a threshold, and excludes the pair of pulses from an evaluation of heart beat variation when the stability measure fails to meet the threshold.12-22-2011
20090054793Cardiac pressure monitoring device - A cardiac pressure monitoring device includes a fixation member defining a central opening to facilitate slidably positioning the fixation device about a pacemaker lead wire. At least one sensor is coupled to the fixation member. The at least one sensor is configured to sense a physical, chemical, and/or physiological parameter within a cardiac chamber.02-26-2009
20110319771VITAL LUMINAL PART EVALUATING APPARATUS - A pressure vessel is provided with an annular inflation bag and an annular inflation bag for sealing the pressure vessel at intermediate positions of brachium and antebrachium of the live body in longitudinal direction of the arms of the live body, and is configured to permit a change of an internal pressure therein over a pressure range a lower limit of which is a negative value, while a portion of the brachium and antebrachium between first and second positions in the longitudinal direction is accommodated in the pressure vessel, so that the pressure vessel can be comparatively small-sized even where arterial vessel (luminal part) of a comparatively large diameter is accommodated in the pressure vessel, whereby the physical and mental burden on the subject person can be reduced.12-29-2011
20110319770FUNCTION ADDING MODULE - A function adding module includes a connection portion for connection to an existing blood pressure meter with an air tube and a connection portion for connection to a cuff with an air tube. The function adding module calculates a pressure value by detecting a change in internal pressure of the cuff using an embedded pressure sensor. The function adding module has a memory function and stores the calculated blood pressure value in a memory.12-29-2011
20120029365MEASUREMENT OF CARDIAC CYCLE LENGTH AND PRESSURE METRICS FROM PULMONARY ARTERIAL PRESSURE - Various techniques for measuring cardiac cycle length and pressure metrics based on pulmonary artery pressures are described. One example method described includes identifying a point within a derivative signal of a cardiovascular pressure signal without reference to electrical activity of a heart, initiating a time window from the identified point in the derivative signal, identifying a point within the cardiovascular signal within the time window, and determining at least one of a systolic pressure or diastolic pressure based on the identified point.02-02-2012
20120029364MEASUREMENT OF CARDIAC CYCLE LENGTH AND PRESSURE METRICS FROM PULMONARY ARTERIAL PRESSURE - Various techniques for measuring cardiac cycle length and pressure metrics based on pulmonary artery pressures are described. One example method described includes identifying a point within a derivative signal of a cardiovascular pressure signal without reference to electrical activity of a heart, initiating a time window from the identified point in the derivative signal, identifying a point within the cardiovascular signal within the time window, and determining at least one of a systolic pressure or diastolic pressure based on the identified point.02-02-2012
20120029363SYSTEMS AND METHODS FOR IMPROVED COMPUTATION OF DIFFERENTIAL PULSE TRANSIT TIME FROM PHOTOPLETHYSMOGRAPH SIGNALS - Systems and methods for processing photoplethysmograph (PPG) signals to determine a differential pulse transit time (DPTT) are disclosed. Sensors may be used to obtain first and second PPG signals from a subject. The sensors may be placed at different locations on the subject's body. A first algorithm may be performed on the PPG signals or on signals derived from them to obtain a DPTT. A corresponding confidence measure may be determined and if the confidence measure falls within a first numerical range, the calculated DPTT may be used. On the other hand, if the confidence measure falls within a second numerical range, an alternative algorithm may be performed on the PPG signals or on signals derived from them and the DPTT obtained using the alternative algorithm may be used. The DPTT may be used to perform continuous or periodic measurements of blood pressure.02-02-2012
20080300494REAL-TIME MEASUREMENT OF VENTRICULAR STROKE VOLUME VARIATIONS BY CONTINUOUS ARTERIAL PULSE CONTOUR ANALYSIS - Ventricular stroke volume variation (SVV) is estimated as a function of the standard deviation of arterial blood pressure value measured over each of at least two cardiac cycles, preferably over each of the cardiac cycles in a computation interval covering a full respiratory cycle. In one embodiment, maximum and minimum standard deviation values are determined over the computation interval. SVV is then estimated proportional to the ratio of the difference between the maximum and minimum standard deviation values and the mean of the standard deviation values. In another embodiment, SVV is then estimated proportional to the ratio of the standard deviation of the standard deviation values and the mean standard deviation over the entire computation interval. A pre-processing arrangement for improving reliability of estimates of more general cardiac or hemodynamic parameters is also disclosed and involves smoothing with an approximating function, and sampling and low-pass filtering at an adjustable rate.12-04-2008
20120065525PRESSURE GAUGE, BLOOD PRESSURE GAUGE, METHOD OF DETERMINING PRESSURE VALUES, METHOD OF CALIBRATING A PRESSURE GAUGE, AND COMPUTER PROGRAM - A pressure gauge for determining at least one pressure value describing a pressure of a fluid flowing in a pulsating manner in a phase of the pulsating flow, includes a pulse wave characterizer. The pulse wave characterizer is configured to obtain transmit time information of a pulse wave, and amplitude information of the pulse wave. The pressure gauge additionally includes a pressure value determiner configured to obtain a first pressure value describing a pressure of the fluid in a first phase, on the basis of the transmit time information and while using a mapping. The pressure value determiner is further configured to obtain a second pressure value describing a pressure of the fluid in a second phase, on the basis of the first pressure value and the amplitude information while using a mapping.03-15-2012
20120071767PULMONARY ARTERY PRESSURE ESTIMATOR - A pulmonary artery pressure estimator attaches a plurality of acoustic sensors to a patient so as to measure a second heart sound. The sensors are arranged so that an A2 component of the second heart sound is maximized from at least one of the sensors and a P2 component is maximized from at least another one of the sensors. Electrodes are also attached to the patient so as to measure a cardiac interval. A splitting interval is derived from the A2 and P2 components, which is normalized by the cardiac interval. The normalized splitting interval provides an estimation of the pulmonary artery pressure (PAP).03-22-2012

Patent applications in class Measuring pressure in heart or blood vessel

Patent applications in all subclasses Measuring pressure in heart or blood vessel