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Combined with therapeutic or diverse diagnostic device

Subclass of:

600 - Surgery

600300000 - DIAGNOSTIC TESTING

600407000 - Detecting nuclear, electromagnetic, or ultrasonic radiation

600410000 - Magnetic resonance imaging or spectroscopy

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DocumentTitleDate
20100063382Specific Gene Polymorphisms in Breast Cancer Diagnosis, Prevention and Treatment - A method for detecting a predisposition to breast cancer in a subject is provided. The method comprises detecting in a biological sample from the subject one or more polymorphisms in the sequence of CD44 gene. The presence of one or more polymorphisms in the sequence of CD44 gene indicates that the subject has a predisposition for developing breast cancer.03-11-2010
20110178388MAGNETIC RESONANCE IMAGING APPARATUS - According to one embodiment, an image processing apparatus includes a storage unit configured to store data of a series of images associated with a range including a heart and diaphragm of an object, a moving amount generating unit configured to generate a temporal change in moving amount of the diaphragm and a temporal change in moving amount of the heart from the series of images, and a ratio calculation unit configured to calculate a ratio of the moving amount of the heart to the moving amount of the diaphragm.07-21-2011
20110201918Radiotherapy and imaging apparatus - A radiotherapy system comprises a patient support, moveable along a translation axis, an imaging apparatus, comprising a first magnetic coil and a second magnetic coil, the first and second magnetic coils having a common central axis parallel to the translation axis, and being displaced from one another along the central axis to form a gap therebetween, the imaging apparatus being configured to obtain an image of a patient on the patient support and a source of radiation mounted on a chassis, the chassis being rotatable about the central axis and the source being adapted to emit a beam of radiation through the gap along a beam axis that intersects with the central axis, the beam having a first extent in a first direction parallel to the central axis, and a second, greater extent in a second direction transverse to the central axis.08-18-2011
20120203095Systems and Methods for Trans-Orifice and Transperineal Intervention - An intervention apparatus is described having a probe with an orifice insertion portion, the insertion portion being configured for insertion into an orifice of a patient. The apparatus also having an intervention tool securement and adjustment mechanism removably attached to the probe. The probe providing support to hold the mechanism in a position relative to the patient, and the adjustment mechanism providing adjustment of an entry point and an angle of entry for an intervention tool to the patient. In embodiments, magnetic resonance imaging, trans-orifice intervention and transperineal intervention are described. Methods for imaging and/or intervention are also described.08-09-2012
20130030282SYNTHESIS AND CHARACTERIZATION OF NEAR IR FLUORESCENT MAGNETIC AND NON-MAGNETIC ALBUMIN NANOPARTICLES FOR BIOMEDICAL APPLICATIONS - The present invention discloses Near Infrared (NIR) fluorescent albumin nanoparticles having a structure selected from a core structure or a core-shell structure. Also disclosed are a process of preparing these NIR fluorescent albumin nanoparticles, and a method of in vivo detection of pathologies, in particular cancer pathology, by using administering these NIR fluorescent albumin nanoparticles to a patient.01-31-2013
20130030283Motion Compensated Image-Guided Focused Ultrasound Therapy System - An image-guide therapy system comprises a thermal treatment device (e.g., an ultrasound transducer) configured for transmitting a therapeutic energy beam, and The system further comprises an imaging device (e.g., a magnetic resonant imaging (MRI) device) configured for acquiring images of the target tissue mass and the thermal treatment device. The system further comprises a controller configured for controlling thermal dose properties of the thermal treatment device to focus the energy beam on a target tissue mass located in an internal body region of a patient, and a processor configured for tracking respective positions of the thermal treatment device and the target tissue mass in a common coordinate system based on the acquired images. The system may optionally comprise a display configured for displaying the acquired images.01-31-2013
20120172707METHOD FOR DEVELOPING AN INFORMATION PREDICTION DEVICE, USE THEREOF, AND CORRESPONDING STORAGE MEDIUM AND APPARATUS - A method for developing a prediction device for predicting a phenotype of a person from imaging data of the person is provided. The method includes determining imaging descriptors, the determining imaging descriptors including acquiring multidimensional images of people with an imaging apparatus and extracting multidimensional image elements from the acquired multidimensional images to serve as descriptors The method also includes classifying the predetermined descriptors on the basis of the capability thereof to predict the phenotype, selecting, from among the classified descriptors, a relevant number of the best-classified descriptors that is sufficient to predict the phenotype and constructing the prediction device from the selected descriptors.07-05-2012
20100022867MAGNETIC RESONANCE IMAGING APPARATUS - With a view to attaining a high quality of a diagnostic image there is provided a magnetic resonance imaging apparatus wherein an image is formed on the basis of magnetic resonance signals received from a subject with an electromagnetic wave transmitted thereto in a static magnetic field. The magnetic resonance imaging apparatus is provided with plural receiving coil units for receiving the magnetic resonance signals, the receiving coil units each comprising a coil body configured to receive a corresponding one of the magnetic resonance signals and output an electrical signal and an optical modulator configured to use an electric field of the electric signal outputted from the coil body directly as a modulation signal.01-28-2010
20090326366METHOD FOR VISUALLY MONITORING AN IRREVERSIBLE ELECTROPORATION TREATMENT, AND MAGNETIC RESONANCE IMAGING APPARATUS WITH INTEGRATED ELECTROPORATION TREATMENT DEVICE - In a method for implementing an irreversible electroporation treatment with an electroporation device having at least two treatment electrodes, magnetic resonance exposures are acquired for visual monitoring of the treatment, and magnetic resonance-compatible electrodes are used as treatment electrodes. A magnetic resonance imaging apparatus has an electroporation device integrated therein, so as to be operable by co-use of at least some of the same components that arte used for image data acquisition.12-31-2009
20100152570Virtual Penetrating Mirror Device for Visualizing Virtual Objects in Angiographic Applications - A virtual mirror device for visualizing virtual objects in angiographic applications, having an interactive virtual mirror, a 3D or 4D medical image of a patient's anatomy co-registered with a calibrated 2D X-ray image of the patient's anatomy, and a displaying device provided such that the 2D X-ray image of the patient's anatomy, the co-registered 3D or 4D medical image of the patient's anatomy and the interactive virtual mirror viewed from the viewpoint of the X-ray source of the X-ray imaging system, are presented in a common coordinate system, providing full integration and combined visualization of the reconstruction of 3D or 4D medical image of the patient's anatomy, the 2D X-ray image of the patient's anatomy and the virtual mirror onto the displaying device.06-17-2010
20090192383METHOD AND DEVICE FOR OBTAINING INFORMATION ABOUT A MAMMALIAN BODY - This invention relates to a device for retrieving information about one or more states of a mammalian body comprising: (a) a magnetic resonance imaging device comprising a first set of one or more radio-frequency coils for measuring the body temperature Ti at a selected location of a mammalian body, (b) a local heating means including a second set of one or more radio-frequency coils, said second set comprising at least two channels for delivering focused radio frequency energy to said selected location of said mammalian body and raising the temperature Ti thereof, and (c) means for modulating said radio-frequency energy delivered by said second set of coils as a function of said temperature Ti in order to reach and maintain a predefined temperature Tp above the normal mammalian body temperature Tb.07-30-2009
20110196228PET-MRI HYBRID APPARATUS AND METHOD OF IMPLEMENTING THE SAME - There is provided a PET-MRI hybrid apparatus and method for integrating a PET image and an MRI image so that anatomical, hemodynamical and molecular information on human tissues are simultaneously presented in a single image. The PET-MRI hybrid system comprises a first scanner for obtaining anatomical and hemodynamical information, and a second scanner for obtaining molecular and functional information on the human tissues. Along a path between the first scanner and the second scanner, a transferring railway system which includes runs, and a movable bed for supporting a subject installed on the railway. The PET-MRI hybrid system also comprises a “RF+magnetic” shield and a “magnetic” shield between path between the first scanner and the second scanner, which switch between an open status and a close status in a completely synchronized manner to assure a complete magnetic shield for the PET system at any given time. The subject is fastened on the bed and transferred along the railway between the first and second scanner to provide accurately fused MRI and PET images.08-11-2011
20110196227Apparatus with a Combination of a Magnetic Resonance Apparatus and a Radiotherapy Apparatus - An apparatus with a combination of a magnetic resonance apparatus is proposed. The apparatus has at least one main magnet for generating a magnetic field in an examination area for a magnetic resonance measurement and a radiotherapy apparatus which is designed for generating a particle beam. A direction of a speed of the particle beam is aligned substantially in parallel to a direction of a magnetic flux density of the magnetic field.08-11-2011
20110196226Apparatus Having a Combined Magnetic Resonance Apparatus and Radiation Therapy Apparatus - An apparatus having a combined magnetic resonance apparatus is proposed. The magnetic resonance apparatus features at least one main magnet for generating a main magnetic field in an examination space for a magnetic resonance measurement, and a radiation therapy apparatus, which is provided to generate a particle beam and which features a beam guide. The magnetic resonance apparatus features an essentially magnetic-field-free region and the beam guide for the particle beam runs along the essentially magnetic-field-free region.08-11-2011
20100113911System for Delivering Conformal Radiation Therapy While Simultaneously Imaging Soft Tissue - A device and a process for performing high temporal- and spatial-resolution MR imaging of the anatomy of a patient during intensity modulated radiation therapy (IMRT) to directly measure and control the highly conformal ionizing radiation dose delivered to the patient for the treatment of diseases caused by proliferative tissue disorders. This invention combines the technologies of open MRI, multileaf-collimator or compensating filter-based IMRT delivery, and cobalt teletherapy into a single co-registered and gantry mounted system.05-06-2010
20100076300DATA PROCESSING SYSTEM FOR MULTI-MODALITY IMAGING - A data processing process and embodiment for optimizing the signal path for multi-modality imaging is described. The embodiment and process optimizes the signal to noise ratio in a positron emission tomography (PET) signal path utilizing scintillation crystals, avalanche photo diodes, and charge sensitive preamplifiers in a dual modality MRI/PET scanner. The dual use of both and analog pole zero circuit and a digital filter enables higher signal levels or a fixed ADC input range and thus a higher possible signal to noise ratio in the presence of significant pileup caused by high positron activity. The higher signal to noise ratio is needed in the PET signal architecture, because of the presence of non-modal time varying electromagnetic fields from the MR, which are a significant source of noise for the wideband PET signal modality.03-25-2010
20100076299Inducing Desirable Temperature Effects On Body Tissue Using Alternate Energy Sources - A system for inducing desirable temperature effects on body tissue, the body tissue being disposed about a lumen. The system includes an elongate catheter having a proximal end and a distal end with an axis therebetween with an energy delivery portion for transmission of energy. A tissue analyzer configured to characterize the body tissue in the lumen proximate the energy delivery portion and an energy source coupled to the energy delivery portion transmitting tissue treatment energy, wherein the energy is non-RF energy. A processor coupled to the tissue analyzer and energy source, the processor configured to determine an appropriate treatment energy for the characterized body tissue so as to mildly heat the body tissue with the energy delivery portion without ablating.03-25-2010
20100076301ADAPTIVE IMAGING PARAMETERS WITH MRI - Systems, methodologies, media, and other embodiments associated with automatically adapting MRI controlling parameters are described. One exemplary method embodiment includes configuring an MRI apparatus to acquire MR signal data using a non-rectilinear trajectory. The example method may also include acquiring MR signals, transforming the MR signals into image data, and selectively adapting the MRI controlling parameters based, at least in part, on information associated with the MR signals.03-25-2010
20100076298METHOD AND DEVICE FOR DETERMINING THE SPATIAL DISTRIBUTION OF THE SPECIFIC ABSORPTION RATE PRODUCED BY AN ELECTROMAGNETIC FIELD-RADIATING APPARATUS - In a method to determine the spatial distribution of the specific absorption rate in tissue that represents a measure of the absorption of electromagnetic fields emitted by means of a radiation generating element, at least one item of measurement information acquired by a thermoacoustic computed tomography device is used to determine the specific absorption rate.03-25-2010
20130079625CT - MRI HYRBRID APPARATUS AND METHOD OF IMPLEMENTING THE SAME - An apparatus and method for non-invasively obtaining an image featuring information on internal human tissues, and more particularly to an apparatus and method for integrating computed tomography (CT) or computerized axial tomography (CAT) and magnetic resonance imaging (MRI) to provide high spatial-accurate resolution images which feature tumor information on human internal tissues especially as a part of a radiotherapy treatment. The apparatus includes a first section for obtaining a first set of images of a subject using a first method, a second section for obtaining a second set of images of the subject using the second method, the second method being different from the first method, and a board for carrying the subject through the first and second sections, the board being movable between the first and second sections.03-28-2013
20130035582HIGH INTENSITY FOCUSED ULTRASOUND TRANSDUCER OPTIMIZATION - When planning magnetic resonance (MR) guided high intensity focused ultrasonic (HIFU) therapy, HIFU transducer element parameters are optimized as a function of 3D MR data describing a size, shape, and position of a region of interest (ROI) (02-07-2013
20090171184MRI SURGICAL SYSTEMS FOR REAL-TIME VISUALIZATIONS USING MRI IMAGE DATA AND PREDEFINED DATA OF SURGICAL TOOLS - MRI-Surgical systems include: (a) at least one MRI-compatible surgical tool; (b) a circuit adapted to communicate with an MRI scanner; and (c) at least one display in communication with the circuit. The circuit electronically recognizes predefined physical characteristics of the at least one tool to automatically segment MR image data provided by the MRI scanner whereby the at least one tool constitutes a point of interface with the system. The circuit is configured to provide a User Interface that defines workflow progression for an MRI-guided surgical procedure and allows a user to select steps in the workflow, and wherein the circuit is configured to generate multi-dimensional visualizations using the predefined data of the at least one tool and data from MRI images of the patient in substantially real time during the surgical procedure.07-02-2009
20130035587Radiotherapy Apparatus - A radiotherapy apparatus is described which includes a patient support, a magnetic resonance imaging (MRI) apparatus for obtaining imaging data of a patient positioned on the patient support, and multiple linear accelerators, each aligned in a plane transverse to the patient support and arranged to provide a therapeutic beam of x-ray radiation to the patient.02-07-2013
20130035586Radiotherapeutic Apparatus - We provide a radiotherapeutic apparatus comprising a patient support, magnetic coils disposed around the patient support for creating a magnetic field therewithin, a radiation source producing a beam of radiation directed toward the patient support and mounted on a rotatable support thereby to rotate the radiation source around the patient support, a slip ring for conveying electrical power to the radiation source and located around the patient support, including at least one electrical interruption therein. This creates a slip ring in which there is no continuous circumferential path, and one in which the current is therefore forced to take a route via one side or the other.02-07-2013
20130035585INSTRUMENT GUIDING DURING MAGNETIC RESONANCE IMAGING - The invention relates to a preparing apparatus for preparing an influencing procedure for influencing a subject. The preparing apparatus (02-07-2013
20130035584Robotic Linac Adaptation (RLA) for the in-line MRI-linac Configuration - An in-line MRI-linac apparatus is provided that includes an MRI magnet of an MRI scanner, where the MRI magnetic includes a magnetic field, where the magnetic field has a quasi-uniform fringe field, where the fringe field is proximal to an axis of symmetry of the MRI magnet, and a magnetically unshielded dynamically moveable linac that includes a treatment beam that is aligned with field lines of the fringe field in a quasi axial symmetric configuration, where a position of the linac in the fringe field continuously adapts according to a target position to enable continuous dose delivery to the target.02-07-2013
20130035583METHOD AND APPARATUS FOR PROCESSING MEDICAL IMAGE, AND ROBOTIC SURGERY SYSTEM USING IMAGE GUIDANCE - A synthesis image in which medical images captured using different medical image capturing apparatuses are registered is generated by mapping the medical images to each other. The synthesis image may be used for image guidance while a diagnosis or a robotic surgery of a patient is being performed.02-07-2013
20130041249METHOD FOR TEMPERATURE CONTROL IN MAGNETIC RESONANCE-GUIDED VOLUMETRIC ULTRASOUND THERAPY - In a method for temperature control in MR-guided administration of ultrasound, ultrasound therapy is administered to a patient at an in vivo site by emitting focused ultrasound into the site at multiple foci with a multi-focus ultrasound therapy device. The temperature is monitored in a localized region of an examination subject in which the site is located firing said therapy in real-time by MR thermometry. From the MR thermometry, characteristics of the temperature distribution in the monitored region of the examination subject are automatically identified. Temperature control is implemented by regulating the energy output of the ultrasound therapy device, according to a rapidly converging master equation.02-14-2013
20100099976GAMMA- RAY DETECTOR AND PET APPARATUS USING THE SAME - A medium area (S) filled with liquid xenon (04-22-2010
20100099975DETECTION OF DECEPTION AND TRUTH-TELLING USING FMRI OF THE BRAIN - Methods for deriving an indication of truth or deception are disclosed. Some methods include (a) monitoring the activation of a plurality of regions of a subject's brain, while the subject responds to questions and (b) measuring one or more physiological parameters while the subject responds to questions and combining the results of (a) and (b) to form a composite evaluation indicative of truth or deception in the subject's response. Another method further includes (c) measuring one or more behavioral components while the subject responds to questions and then combining the results of (a), (b), and (c) to form a composite evaluation indicative of truth or deception in the subject's response. Methods for scoring, weighting, and combining the measurements for (a), (b), and (c), and combinations thereof, are also disclosed.04-22-2010
20100041979INTERVENTIONAL IMMOBILIZATION DEVICE - Interventional immobilization devices used to immobilize a body part and then, during a medical procedure, orient a medical device to treat located tissue within the body part are provided. The devices are designed to immobilize body tissue while preserving, or substantially preserving, the three-dimensional or volumetric integrity of the immobilized tissue. The device enables real time (RT) imaging-guided interventional (IGI) capabilities when the devices are coupled with medical imaging systems, such as magnetic resonance imaging (MRI) systems.02-18-2010
20100106005MRI-GUIDED HIFU MARKING TO GUIDE RADIOTHERAPY AND OTHER PROCEDURES - The present disclosure provides for effective systems and methods for increasing target tissue conspicuity within a particular anatomy of a particular patient. In an exemplary embodiment, a system associated with the present disclosure includes: (a) a MRI-guided HIFU system for generating ablation markings on a target tissue region, the MRI-guided HIFU system including a transducer for delivering HIFU to the target tissue region, the delivered HIFU generating the ablation markings on the target tissue and an MRI imaging system adapted to generate a three dimensional image of the target tissue region during HIFU delivery for guiding the delivery of the HIFU to the target tissue region; (b) a radiotherapy delivery system for delivering radiotherapy treatment to the target tissue region; and (c) a CT imaging system operable within the radiotherapy delivery system for generating a three dimensional image of the target tissue region. The markings generated on the target tissue region by the MRI-guided HIFU are visible in the image generated by the CT imaging system. The image generated by the CT imaging system guides the location of the radiotherapy treatment delivered to the target tissue region.04-29-2010
20100106004MOTION CORRECTION IN A PET/MRI HYBRID IMAGING SYSTEM - A diagnostic imaging arrangement comprises a magnetic resonance examination (04-29-2010
20090069667DEVICE FOR POSITIONING AN ULTRASOUND TRANSDUCER INSIDE A MR SCANNER03-12-2009
20090131782Device for Heat Treating Moving Biological Tissues and Related Method - This invention concerns a device for heat treating a moving target area of biological tissues, comprising calculation means (05-21-2009
20100331667AUTOMATED NON-MAGNETIC MEDICAL MONITOR USING PIEZOELECTRIC CERAMIC DIAPHRAGM DEVICES - In magnetic resonance imaging (MRI), the powerful magnetic fields can interfere with, damage, cause premature failure in, and attract certain non-MR safe instruments. Electromagnetic ally sensitive components are eliminated in favor of MR safe components, such as ceramic piezoelectric components and bi-metallic components. Instruments that previously had to be kept a safe distance away from the main magnet (12-30-2010
20090240137Diagnostic Imaging Method - A method of identifying injury to soft connective tissues in complicated body joints deploys use of motion x-ray images as the joint moves to identify suspected abnormal pathology followed by Dynamic Upright MRI images of the joint under conditions that express the abnormal pathology. The Dynamic Upright MRI parameters are based on the suspected pathology. The method is particularly useful in detecting disco/ligamentous and other injuries that often times will not be visualized on conventional recumbent MRI, or static x-rays.09-24-2009
20090124887DEVICE FOR RADIATION THERAPY UNDER IMAGE MONITORING - A device for radiation therapy implemented with image monitoring has a magnetic resonance device and an exposure device. The magnetic resonance device has a magnet and primarily serves for image monitoring an examination object of a patient in an examination volume of the magnetic resonance device. The exposure is fashioned to be static and serves to expose the examination subject in the examination volume with therapeutic beams. The patient (and therefore the examination subject) are supported by a patient positioning device such that the examination subject can be moved relative to the magnetic resonance device and the exposure device around at least one rotation axis.05-14-2009
20120184842METHOD, AN OPTICAL PROBE AND A CONFOCAL MICROSCOPY SYSTEM FOR INSPECTING A SOLID ORGAN - A method to inspect a solid organ in a subject includes introducing a needle in a predetermined area of the solid organ, inserting an optical probe through a lumen of the needle, and imaging the predetermined area using the optical probe. An optical probe to inspect a solid organ in a subject, the optical probe being intended to be positioned in the solid organ through a needle, the optical probe includes an optical fiber bundle, a ferule to protect the distal tip of the optical fiber bundle, the ferule comprising a shank and a head, and a sheath wrapping the fiber bundle and the shank, wherein the head of the ferule has a length adapted for the optical probe to image the solid organ while keeping the sheath inside the needle.07-19-2012
20120184841RETROSPECTIVE CALCULATION OF RADIATION DOSE AND IMPROVED THERAPY PLANNING - A combined magnetic resonance (MR) and radiation therapy system (07-19-2012
20120165653MR imaging system with cardiac coil and defibrillator - The invention relates to a magnetic resonance imaging system comprising a main magnet coil (06-28-2012
20120165652SYSTEM AND METHOD FOR IMAGE GUIDANCE DURING MEDICAL PROCEDURES - A surgical guidance system is disclosed that allows for real-time imaging and patient monitoring during a surgical procedure. The system can include an MRI system for generating real-time images of the patient while surgery is being performed. Prior to surgery, a surgical plan can be created using a planning interface. A control unit receives the real-time image data and the surgical plan, and monitors the image data based on parameters included in the surgical plan. The control-unit monitoring occurs in real-time while the surgical procedure is being performed. The control unit can detect deviations from the surgical plan and/or high-risk patient conditions and instruct an alert unit to issue an alert based on the detected conditions.06-28-2012
20120165650HER2 BINDERS - Imaging agents comprising an isolated polypeptide conjugated with a radionuclide and a chelator; wherein the isolated polypeptide binds specifically to HER2, or a variant thereof; and methods for preparing and using these imaging agents.06-28-2012
20130046168METHOD AND SYSTEM OF CHARACTERIZATION OF CAROTID PLAQUE - A system and method of obtaining and analyzing ultrasound images of a patient provides for the identification of specific tissue types in using the image data. A feature vector set of sub-regions of the region of interest is obtained, dimensionally reduced and evaluated using a heuristic to identify the tissue type. Where the tissue type is suitable for image standardization, the overall gray scale of the image is adjusted with respect to a predetermined gray scale for the identified tissue type. The image may be segmented and plaque regions identified and characterized. The characterized plaque and other parameters such as percent stenosis may be used to determine a risk score for the patient.02-21-2013
20130046170DETERMINING RESPIRATORY OR CIRCULATORY HEALTH CONDITION IN ANIMALS FOR IMPROVED MANAGEMENT - A method and system for managing at least one animal is disclosed. The method can include imaging, such as ultrasound imaging, a lung of a live animal, such as a ruminant or bovine. The imaging can be performed to determine a degree of respiratory damage from past respiratory illness. After imaging, information regarding respiratory damage can be used to select at least one aspect of the treatment, care or disposition of the animal. For example, the information can be used to select the amount or type of feed provided to the animal at a feedlot. The information also can be used to select how long the animal should be housed at the feedlot prior to slaughter. If an animal is diagnosed with a respiratory illness, information about its degree of respiratory damage from past respiratory illness also can be used to select the appropriate medical treatment or lack of treatment.02-21-2013
20130046169MRI-GUIDED NANOPARTICLE CANCER THERAPY APPARATUS AND METHODOLOGY - An apparatus and method direct nanoparticles in a body part under imaging guidance using at least one electromagnet configured and operable to create a magnetic field gradient used to direct the nanoparticles, wherein, the magnetic field gradient used to direct the nanoparticles does not substantially interfere with the use of magnetic field gradients whose purpose is to image the body part.02-21-2013
20100130850Flexible Core Surgical Device - A surgical instrument having a tubular member having a proximal end and a distal end, at least one helical member concentric with the tubular member, and a cutting portion protruding from the distal end of the tubular member. A method of using the surgical instrument is performing a biopsy.05-27-2010
20130090550METHODS OF IDENTIFYING PATIENTS WITH OVARIAN EPITHELIAL NEOPLASMS BASED ON HIGH-RESOLUTION MASS SPECTROMETRY - Methods for identifying patients with ovarian neoplasms are provided herein comprising performing an assay step of detecting a metabolite in a serum sample of a patient where the metabolite is probably not produced by a tumor but could induce the development of a tumor, and the presence of the metabolite being indicative of an increased likelihood that the patient has ovarian cancer,04-11-2013
20130090549SIMULTANEOUS MULTI-MODALITY INVERSE OPTIMIZATION FOR RADIOTHERAPY TREATMENT PLANNING - When performing multimodal radiotherapy planning, an optimizer (04-11-2013
20130090548AUTOMATED RENAL EVALUATION SYSTEMS AND METHODS USING MRI IMAGE DATA - Renal screening systems include a circuit configured to electronically analyze MRI image data of a subject to evaluate renal function and generate a renal-risk report for a plurality of different therapeutic agents based on renal responses to test doses of each of the agents.04-11-2013
20130090547Combined Imaging Modalities for Radiation Treatment Planning - A system includes acquisition of a first three-dimensional image of a patient volume using a magnetic resonance imaging scanner, acquisition of a second three-dimensional image of the patient volume using cone beam radiation emitted by the linear accelerator, and generation of a radiation treatment plan based on the first image and the second image.04-11-2013
20130090546SPINAL CORD FUNCTION ASSESSMENT - A device, system and methods are described for stimulating multiple dermatones on a body in accordance with a stimulation pattern. Magnetic resonance images are captured during the application of the stimulation pattern and the captured images are processed. The images are processed using information about the applied stimulation pattern to assess spinal cord function.04-11-2013
20080312526HYBRID PET/MR IMAGING SYSTEMS - A hybrid imaging system includes a magnetic resonance scanner and a second modality imaging system disposed in the same radio frequency isolation space. The second modality imaging system includes radiation detectors configured to detect at least one of high energy particles and high energy photons. In some embodiments a retractable radio frequency screen is selectively extendible into a gap between the magnetic resonance scanner and the second modality imaging system. In some embodiments shim coils are disposed with the magnetic resonance scanner and are configured to compensate for distortion of the static magnetic field of the magnetic resonance scanner produced by proximity of the second modality imaging system.12-18-2008
20090306494SYSTEM FOR MAGNETIC RESONANCE AND X-RAY IMAGING - A patient table for a common imaging system including Magnetic Resonance and X-Ray retains the patient stationary in position prior to, during and subsequent to the imaging and includes a base, a patient support portion cantilevered from the base and a mattress. A safety system is provided for controlling the operation of the magnet and MR system and the X-Ray systems to allow effective safe operation and controls the movement of the magnet to the table and the movement of the X-Ray imaging systems to and from the table to locations where they do not interfere with the MR imaging.12-10-2009
20090093710Optically coupled readout front-end for imaging system - A front end for an imaging system. The front end comprises at least one magnetically-insensitive high-energy photon detector and an interface for converting an output of the at least one high-energy photon detector to an optical signal and transmitting the optical signal. A receiver is optically coupled to the interface to receive the optical signal and convert the optical signal into a voltage signal.04-09-2009
20090093708MRI guided high-intensity focused ultrasonic therapeutic system - A MRI guided high-intensity focused ultrasonic therapeutic system comprises: a MRI apparatus and a high-intensity focused ultrasonic therapeutic apparatus. Said MRI apparatus includes the first treatment bed and said high-intensity focused ultrasonic therapeutic apparatus includes an ultrasound transducer and a moving and positioning means, which drives said transducer to move in respective directions. Wherein, said moving and positioning means is placed outside of the bore of the MRI apparatus during treatment and a supporting rod, which can extend into the bore of the MRI apparatus, is connected to said moving and positioning means at one end and is connected to said ultrasound transducer at the other end. In the system provided by the present invention, said ultrasound transducer can move in multiple orientations, freely move without any limitation of space under the treatment bed, brings less interference to the MRI apparatus, fully exerts the function and efficiency of the MRI apparatus and achieves the best therapeutic effects.04-09-2009
20090093709Noise reduction system and methods for magnetic resonance imaging - In one aspect, a method for noise reduction in parallel magnetic resonance (MR) imaging using a plurality of radio frequency (RF) coils is provided. The method comprises performing a first MR scan of a target to obtain first MR data, performing a second MR scan of the target to obtain second MR data, the second MR data obtained from operating the plurality of coils substantially in parallel, computing a noise estimate associated with the second MR data based at least in part on the first and second MR data, and obtaining a noise-reduced image based at least in part on the second MR data and the noise estimate.04-09-2009
20130060127ULTRASONICALLY VISIBLE SCORING BALLOON - An angioplasty balloon (03-07-2013
20130060128METHOD FOR OPERATING A RADIATION THERAPY SYSTEM - A method is disclosed for operating a radiation therapy system. The radiation therapy system includes a magnetic resonance apparatus. In an embodiment of the method, an irradiation plan is received for a patient. While the patient is arranged in the radiation therapy system and a hyperpolarized contrast agent has been administered, magnetic resonance data of the patient is acquired. In the magnetic resonance data, molecular irradiation target areas are determined on the basis of the hyperpolarized contrast agent and the received irradiation plan is corrected as a function of the molecular irradiation target areas determined in the magnetic resonance data. A molecular irradiation target area relates to an area of the patient with a molecular property.03-07-2013
20110015516METHOD AND MAGNETIC RESONANCE DEVICE FOR GRAPHICALLY ASSISTING NAVIGATION OF AN INSTRUMENT - In a method and magnetic resonance device for graphically assisting the navigation of an instrument (in particular a medical instrument such as a needle and/or a guide sleeve guiding a needle) within a procedure region of a target subject (in particular a patient), coordinates of a target position and/or target region to be addressed that are obtained from a high-contrast image data set acquired with the magnetic resonance device. Low-contrast image data showing the instrument are acquired continuously and/or intermittently during the navigation and/or the position and orientation of the instrument is determined (in particular measured) with a position determination device. The low-contrast image later are brought into registration with the magnetic resonance device continuously and/or intermittently during the navigation. A representation showing at least the relative position and orientation of the instrument relative to the target position and/or target region is generated and displayed under consideration of the coordinates and the low-contrast image data and/or the position and orientation of the instrument.01-20-2011
20120190966MR Compatible Fluorescence Viewing Device for use in the Bore of an MR Magnet - In an MR guided surgical system which is carried out in the bore of an MR magnet and uses fluorescence to detect tumor cells, there is provided a microscope system for viewing the required part of a patient which includes stereoscopic viewing components arranged for use in generating 2D and 3D images displayed to the surgeon. The optical assembly is adjustable to change the view and the visual images are overlaid by the MR images. The visual image can be adjusted in response to movement of the surgical tool and the MR image displayed and/or the image obtained can be modified in response to change in the visual image and/or movement of the tool. The components in the bore are made compatible with the MR environment. A fluorescence delivery system is operated to automatically activate the delivery system in response to detection of the level of fluorescence.07-26-2012
20090270718DUAL-MODALITY IMAGING - The invention relates to a dual-modality imaging system and a method for dual-modality imaging of an imaged object, wherein a magnetic resonance imaging (MRI) apparatus for acquiring MRI data and at least one optical imaging detector for acquiring optical imaging data are arranged to acquire the MRI data and the optical imaging data of the imaged object (10-29-2009
20090270717APPARATUS AND METHOD FOR DIAGNOSIS OF OPTICALLY IDENTIFIABLE OPHTHALMIC CONDITIONS - An apparatus that can discriminate various conditions of neurological health of a medical subject. The apparatus and method use the Frequency Doubling Technique to obtain data that is indicative of a state of health of a person being tested. Correlations to features such as for patterns of loss such as point-wise loss, peripheral vs. central loss, pattern standard deviation, mean deviation, and time to complete the test can be used to identify the condition of the person. The apparatus and method thereby provide guidance as to the presence of a medical condition in a patient. The apparatus and method can be used in an iterative measurement process, in which the apparatus attempts to discern normal health from a state of health that is not normal health.10-29-2009
20090270715Correction method and magnetic resonance device - The invention relates to a correction method for correcting interference due to gradient injections in ECG signal data records recorded in a magnetic resonance device by an ECG measuring device. A first correction data record is determined with the ECG measuring device located in a first position. A second correction data record is determined by the ECG measuring device located in a second position. An ECG signal data record is measured by the ECG measuring device located in a defined position. A modified correction data record is defined as a function of the first correction data record and the second correction data record and the first and second position and the defined position of the ECG measuring device. The ECG signal data record is corrected based on the modified correction data record.10-29-2009
20090270716Correction method and magnetic resonance device - The invention relates to a correction method for correction of noise resulting from gradient artifacts in ECG signal data records recorded in a magnetic resonance device by an ECG measuring apparatus. A first correction data record is determined with a reference point of the ECG measuring apparatus located at a first position in the magnetic resonance device. An ECG signal data record is measured with the reference point of the ECG measuring apparatus located at a second position in the magnetic resonance device. A modified correction data record is specified as a function of the first correction data record and the first and second position of the reference point. The ECG signal data record is corrected based on the modified correction data record.10-29-2009
20090270714Device to Treat Chronic Total Occlusions Using Energy Imparted By External Imaging - A visualization and treatment system for treating a chronic total occlusion. The system includes an elongated member configured to be tracked to the chronic total occlusion. The elongated member has a transducer located at a distal end of the elongated member. The transducer is constructed and arranged to convert a first form of energy into a second form of energy to treat the chronic total occlusion. The system also includes an external imaging system constructed and arranged to create an image of the chronic total occlusion and to provide the first form of energy to the transducer.10-29-2009
20120226140SYSTEMS AND METHODS FOR REMOTE MONITORING OF SIGNALS SENSED BY AN IMPLANTABLE MEDICAL DEVICE DURING AN MRI - Systems and methods are provided for allowing an implantable medical device, such as pacemaker, to properly sense electrophysiological signals and hemodynamic signals within a patient during a magnetic resonance imaging (MRI) procedure. Systems and methods are also provided for allowing the implantable medical device to transmit the sensed data to an external monitoring system during the MRI procedure so that attending medical personnel can closely monitor the health of the patient and the operation of the implantable device during the MRI. These improvements provide the attending personnel with information needed to determine whether the MRI should be suspended in response to induced tachyarrhythmias or other adverse conditions within the patient.09-06-2012
20120226139METHOD AND COMPOSITION FOR HYPERTHERMALLY TREATING CELLS - A method and composition for hyperthermally diagnosing and monitoring treatment of cells with photoacoustic sound and nanoparticles.09-06-2012
20120226138METHODS FOR THE IDENTIFICATION AND TARGETING OF BRAIN REGIONS AND STRUCTURES AND TREATMENTS RELATED THERETO - Disclosed herein are methods for identifying and targeting brain regions and brain structures. In one embodiment, a method of identifying a brain structure in a patient comprises imaging a brain region using Diffusion Tensor Imaging MRI to identify a nerve tract, following the nerve tract to a first brain structure, and identifying the first brain structure based on the location and orientation of the nerve tract.09-06-2012
20120197106Parallel Excitation of Nuclear Spins With Local SAR Control - A method of exciting nuclear spins in a sample, wherein a plurality of transmit coils are driven in parallel to emit respective radio-frequency excitation pulses, the method comprising computing the phases and/or amplitudes of said excitation pulses by solving an optimization problem for minimizing the difference between the excitation distribution within said sample and a target excitation distribution, and being characterized in that: said optimization problem includes a cost function depending on the power emitted by said transmit coils through respective coil-dependent weighting coefficients; and in that the phases and/or amplitudes of the excitation pulses are computed iteratively, each iteration step comprising: solving said optimization problem based on present values of the weighting coefficient, and subsequently updating the value of at least one of said coefficients so as to control in a predetermined way the local specific absorption rate—SAR—distribution within the sample. The method of the invention allows, in particular, reducing the local SAR maximum value within the sample and/or ensuring that the local SAR takes its maximum value within a predetermined region of the sample.08-02-2012
20110046472TECHNIQUES FOR TEMPERATURE MEASUREMENT AND CORRECTIONS IN LONG-TERM MAGNETIC RESONANCE THERMOMETRY - Techniques for temperature measurement and correction in long-term MR thermometry utilize a known temperature distribution in an MR imaging area as a baseline for absolute temperature measurement. Phase shifts that arise from magnetic field drifts are detected in one or more portions of the MR imaging area, facilitating correction of temperature measurements in an area of interest.02-24-2011
20100081919Histological facilitation systems and methods - Systems, methods, and other modalities are described for generating or otherwise handling images or other data indicating (a) an extraction of chemically treated tissue frozen in vivo, (b) a treatment of a tissue sample in a chamber extended into tissue of an organism, and/or (c) cells to which an optical enhancement material was applied in vivo. Several contexts in which such indications facilitate histological evaluation are likewise described.04-01-2010
20120116208TEMPERATURE MEASUREMENT NEAR AN ICE BALL USING A PROTON RESONANCE FREQUENCY METHOD AND RECALCULATION OF SUSCEPTIBILITY ARTIFACTS - In a method or system for magnetic resonance imaging based temperature monitoring for real-time feedback to a physician for a cryoablation therapy of a lesion which creates an ice ball of the lesion to induce cell death, the magnetic resonance imaging system, using proton resonance frequency imaging, obtains a real-time temperature image of the ice ball of the lesion undergoing the cryoablation therapy and the adjacent surrounding tissue. By use of an algorithm, correcting temperature errors at a border of the ice ball are corrected in the real-time image, the temperature error correction correcting susceptibility contrast errors caused by a distortion of the local magnetic field at the border of the ice ball.05-10-2012
20090234220Catheter and associated medical examination and treatment device - A catheter for treatment of the heart with a flexible catheter sheath surrounding a catheter lumen and with an apparatus for implanting cell material, which comprises an injection apparatus arranged in an area of the catheter tip, is to be created such that the risk of such an intervention is reduced in relation to previously known and practiced concepts. To this end there is inventive provision for at least one imaging sensor to be arranged in the area of the catheter tip.09-17-2009
20090234219Particle Radiation Therapy Equipment - Particle radiation therapy equipment arranged to apply a charged particle beam to a region of application in a predetermined direction, comprising a charged particle beam source arranged to direct a charged particle beam in the predetermined direction, further comprising magnetic field generation means for generating a magnetic field in an imaging volume which includes the region of application at the same time that the charged particle beam is applied, wherein the magnetic field generation means is arranged to provide access to the region of application for the charged particle beam, and to provide a homogeneous magnetic field in the region of application of the charged particle beam, said magnetic field being directed substantially in the predetermined direction.09-17-2009
20090012387ENCODING AND TRANSMISSION OF SIGNALS AS RF SIGNALS FOR DETECTION USING AN MR APPARATUS - The invention provides a novel way of handling electric or electromagnetic signals during magnetic resonance (MR) measurements. Non-MR data signals such as EPH signals (e.g. EEG, ECG, blood pressure, respiration) or subject responses (e.g. keystrokes, joystick movements) originating in the MR suite is recorded while performing magnetic resonance imaging or spectroscopy. Relatively simple, possibly battery driven hardware is used to transform the non-MR signals into radio waves detectable by the MR apparatus. The electrical signals are in this way encoded as artifacts appearing in the MR images or spectra outside the region of interest, and the encoded signals can subsequently be reconstructed from the signal recorded by the scanner If oversampling is employed, artifacts can be avoided altogether. The method inherently provides superior synchronisation between the sampling of non-MR data signals and the MR sequence. The invention minimises the need for costly special MR adapted equipment and can be applied with scanners for MR imaging as well as with NMR spectrometers.01-08-2009
20100087728ACOUSTIC PALPATION USING NON-INVASIVE ULTRASOUND TECHNIQUES TO IDENTIFY AND LOCALIZE TISSUE ELICITING BIOLOGICAL RESPONSES - Methods and systems for identifying and spatially localizing tissues having certain physiological properties or producing certain biological responses, such as the sensation of pain, in response to the application of intense focused ultrasound (acoustic probing or palpation) are provided. In some embodiments, targeted acoustic probing may be guided or visualized using imaging techniques such as ultrasound imaging or other types of non-invasive imaging techniques.04-08-2010
20120238863Digital Image Storage System and Human Body Data Matching Algorithm for Medical Aesthetic Application - A human body data matching algorithm for medical aesthetic application includes the step of providing a human body image acquisition unit, the step of using the human body image acquisition unit to obtain a digital 3D image data of the body of a person during an optimal lifetime of the person, the step of storing the digital 3D image data in a data storage bank, the step of fetching the digital 3D image data from the data storage bank when going to perform a medical aesthetic surgery, and the step of e) matching the digital 3D image data for reference in the medical aesthetic surgery to avoid communication errors between the patient and the surgeon.09-20-2012
20100049031Non-Thermal Ablation System for Treating BPH and Other Growths - Systems and methods for non-thermal ablation of tissue are provided. A non-implantable minimally invasive system for treatment of tissue in a body via direct current ablation is provided including a catheter, a plurality of electrodes for deployment through the catheter, a power source for applying power to the electrodes, and a fixation element for maintaining the catheter in a treatment position during treatment of the tissue. A minimally invasive method for treating tissue in a body via direct current ablation is provided including inserting a catheter into the body such that a portion of the catheter remains outside of the body, deploying a fixation element to fix the catheter in a treatment position, deploying a plurality of electrodes through the catheter, applying power to the plurality of electrodes, using the electrodes to apply a current to the tissue, and removing the catheter from the body.02-25-2010
20100168553MR-Tracking Based on Magnetic Signature Selective Excitation - The present invention relates to a MR tracking method and device. More specifically, the present invention relates to a magnetic resonance tracking method and device, using a magnetic-susceptible object. A magnetic iso-surface induced by the object is selectively excited with a corresponding frequency offset; the magnetic iso-surface is then projected on three axes of a k-space, from which projections the spatial position of the object is calculated.07-01-2010
20120232377SURGICAL NAVIGATION FOR REVISION SURGICAL PROCEDURE - Surgical navigation for revision surgery includes temporality coupling a reference arc to a surgical object that was substantially permanently affixed to a bone of a patient during a preceding surgery. The reference arc includes a navigation tracker configured to communicate with a navigation system. A surgical instrument is coupled to a respective navigation tracker that is also configured to communicate with the navigation system. A known relationship between the navigation tracker of the reference arc and the navigation tracker of the surgical instrument is used to determine a spatial characteristic of the surgical instrument, such as an position or orientation of the surgical instrument. The spatial characteristic is rendered upon a display unit.09-13-2012
20110282184METHOD FOR POSITIONING THE FOCUS OF A GRADIENT FIELD AND TREATMENT FACILITY - A method for guiding nanoparticles to a target location by a magnetic gradient field and/or holding them at the target location is proposed. The magnetic gradient field is generated by a magnet system with at least one magnet. A focus of the magnet system is registered with an X-ray device. At least one three-dimensional image dataset showing the target location is captured by the X-ray device. The position of the target location is determined manually and/or automatically in the image dataset or in an image dataset determined therefrom and is positioned automatically based on the registration of the focus so that the focus coincides with the position of the target location.11-17-2011
20110301449Radiation Treatment Delivery System With Translatable Ring Gantry - Systems, methods, and related computer program products for image-guided radiation treatment (IGRT) are described. For one preferred embodiment, an IGRT apparatus is provided comprising a ring gantry having a central opening and a radiation treatment head coupled to the ring gantry that is rotatable around the central opening in at least a 180 degree arc. For one preferred embodiment, the apparatus further comprises a gantry translation mechanism configured to translate the ring gantry in a direction of a longitudinal axis extending through the central opening. Noncoplanar radiation treatment delivery can thereby be achieved without requiring movement of the patient. For another preferred embodiment, an independently translatable 3D imaging device distinct from the ring gantry is provided for further achieving at least one of pre-treatment imaging and setup imaging of the target tissue volume without requiring movement of the patient.12-08-2011
20110301450MAGNETIC RESONANCE IMAGING MEDIATED RADIOFREQUENCY ABLATION - Radiofrequency ablation (RFA) may be used as a minimally invasive treatment of solid tumors, typically cancers of the liver, lung, breast, kidney and bone, most often via a percutaneous approach. In RFA tumor tissue is killed by heating. RFA requires guidance using an imaging method to correctly position the RF applicator. Magnetic resonance imaging (MRI) can be used for guidance, and offers the additional advantage of the ability to image tissue temperature. Because MRI employs high power RF fields, the MRI scanner could serve as the source of RF energy for ablation. Described herein are an MRI-driven RF ablation device and method. The device has minimal electrical circuitry, and uses the MR scanner radio frequency field as the energy source to generate heat in tissue using an antenna and a needle. Based on the Faraday induction law, different embodiments for coupling the body coil RF energy into tissue are disclosed.12-08-2011
20110288401BIG BORE PET/MR SYSTEM - A nuclear detector module (11-24-2011
20110288400Methods and Systems for Generating Electrical Property Maps of Biological Structures - A method performed at a computer system having one or more processors and memory storing one or more programs for execution by the one or more processors is disclosed. The method includes accessing multiple images of a biological structure, generating an electrical property map of at least a portion of the biological structure in accordance with two or more of the multiple images, and providing at least a subset of the electrical property map.11-24-2011
20120190967ARRANGEMENT AND METHOD FOR QUANTITATIVELY DETERMINING THE BLOOD FLOW WITHIN BLOOD VESSELS - An arrangement quantitatively determines the blood flow within blood vessels through which blood flows in a volume of a tissue defining a surface. Three-dimensional first image data of a first volume portion of the volume is detected and optical second image data is detected continuously in time of a first surface portion of the surface. A calibrating unit of the arrangement calibrates the relative value of the flow speed and/or the volumetric flow of the blood flowing through the blood vessels disposed directly below the first surface portion based on the absolute values of the flow speed and/or of the volumetric flow of the blood. An output unit outputs the absolute values of the flow speed and/or the volumetric flow of the blood flowing through the blood vessels arranged directly below the first surface portion.07-26-2012
20120271148BRAIN CONDITION MONITORING BASED ON CO-ACTIVATION OF NEURAL NETWORKS - A brain condition can be tracked based on identification of co-activation of two antagonistic networks of a patient's brain. Various embodiments concerns methods and devices for sensing one or more signals indicative of brain activity, detecting one or more episodes of default mode network activation based on the one or more signals, detecting one or more episodes of salience network activation based on the one or more signals, and identifying one or more episodes of temporal co-activation of the default mode network and the salience network based on the detected one or more episodes of default mode network activation and the one or more episodes of salience network activation. The brain condition can be tracked and treated based on the identification of the one or more episodes of co-activation.10-25-2012
20110295105SYSTEMS AND METHODS FOR OPENING A TISSUE - Systems and methods for opening a tissue to a target value are disclosed herein. In an exemplary method, a region of the tissue is targeted for opening, a size range of microbubbles corresponding to the target value is determined, microbubbles of the size range are positioned in proximity to the targeted region, and an ultrasound beam is applied to the targeted region such that the tissue is opened with the assistance of the microbubbles to the target value.12-01-2011
20100249573BRAIN FUNCTION DECODING PROCESS AND SYSTEM - The present invention provides a process of correlating cognitive response to a stimulus by collecting neural activity data from one or more subjects while the subject is exposed to a stimulus. A unique three-dimensional cognitive engram representative of the neural activity caused by the stimulus is then plotted. A unique three-dimensional cognitive engram with biometric data representative of said stimulus is then correlated.09-30-2010
20120190968OBJECT RECOGNITION TESTING TOOLS AND TECHNIQUES FOR MEASURING COGNITIVE ABILITY AND COGNITIVE IMPAIRMENT - Techniques and tools for measuring cognitive ability and/or detecting cognitive impairment or decline. For example, techniques and tools are described that can be used to diagnose or test susceptibility to cognitive impairments in children or in elderly people (such as cognitive impairments associated with Alzheimer's Disease). Techniques and tools are described that can be used to evaluate treatment effects and/or measure cognitive decline over time.07-26-2012
20110270075MULTI-SEGMENT ULTRASOUND TRANSDUCERS - Disclosed are systems and methods for focusing ultrasound transducers that include multiple separate, independently movable transducer segments.11-03-2011
20100063381METHOD FOR DETERMINING AN ITEM OF POSITIONING INFORMATION FOR ECG ELECTRODES DURING AN EXAMINATION WITH A MAGNETIC RESONANCE FACILITY AND MAGNETIC RESONANCE FACILITY - A method for determining an item of positioning information for ECG electrodes during an examination with a magnetic resonance facility is provided. An image data record of a region surrounding the heart of a patient and the electrodes arranged on the surface of the patient is recorded. A position of the longitudinal heart axis and a position of the electrodes in the image data record are determined. A target position suited to determining evaluable ECG signals is automatically calculated for each of the electrodes by considering the position of the longitudinal heart axis and a displacement from the position of the electrodes to the target position. An item of positioning information for the electrodes is displayed by taking the displacements into consideration.03-11-2010
20100036237DETECTOR UNIT FOR ARRANGEMENT WITHIN A FIELD GENERATING UNIT OF AN MR DEVICE - A detector unit for arrangement in a field generating unit of a magnetic resonance device has an RF transmission/reception system for transmitting RF pulses into, or receiving magnetic resonance signals from, an examination volume of the field generation unit. The RF transmission/reception system surrounds a patient tunnel at a radial distance from a tunnel axis thereof, and is divided into two sub-systems located at a distance from each other along the direction of the tunnel axis, so as to form a substantially annular cavity or interstice therebetween.02-11-2010
20100036236METHOD OF INTERFACING A DETACHABLE DISPLAY SYSTEM TO A BASE UNIT FOR USE IN MRI - A base unit operable with a wireless patient monitoring unit used to acquire physiological data during an MRI examination is constructed to have a detachable display unit. The detachable display unit wirelessly communicates with the base unit when in a roving mode. The detachable display unit may also have a magnetically-hardened power supply that does not saturate during an MRI examination. Such a magnetically-hardened power supply allows the display unit to operate when proximate or in the magnetic field generated by an MRI machine during an MRI examination.02-11-2010
20100268064Assembly for heat treatment of biological tissues - The invention concerns an assembly for heat treatment of a region of a biological tissue (10-21-2010
20100268063METHOD AND DEVICE FOR IMAGING A VOLUME SECTION BY WAY OF PET DATA - A method and a device for imaging a volume section by way of PET data are described. With the proposed solution the PET data of the volume section are acquired by way of a positron emission detector, and the MR data of the volume section are acquired by way of a magnetic resonance system. In at least one embodiment, with the aid of the MR data, PET voxels within the volume section are determined from which radiation occurring due to an annihilation is emitted. The image data are reconstructed from the PET data in that it is taken into account that the PET data are generated only by radiation from the PET voxels.10-21-2010
20100121178Systems and Methods for Automated Diagnosis and Decision Support for Breast Imaging - CAD (computer-aided diagnosis) systems and applications for breast imaging are provided, which implement methods to automatically extract and analyze features from a collection of patient information (including image data and/or non-image data) of a subject patient, to provide decision support for various aspects of physician workflow including, for example, automated diagnosis of breast cancer other automated decision support functions that enable decision support for, e.g., screening and staging for breast cancer. The CAD systems implement machine-learning techniques that use a set of training data obtained (learned) from a database of labeled patient cases in one or more relevant clinical domains and/or expert interpretations of such data to enable the CAD systems to “learn” to analyze patient data and make proper diagnostic assessments and decisions for assisting physician workflow.05-13-2010
20110263968Drug-Enhanced Neurofeedback - The present invention relates to techniques and systems for training a subject to modify his or her own neutronal activity within a selected brain region.10-27-2011
20090082660CLINICAL WORKFLOW FOR TREATMENT OF ATRIAL FIBRULATION BY ABLATION USING 3D VISUALIZATION OF PULMONARY VEIN ANTRUM IN 2D FLUOROSCOPIC IMAGES - A system and method of treatment of a patient in a catheterization laboratory is described. A three dimensional (3D) voxel data set of the patient is obtained using a computed tomography device. The data is displayed in a multiplanar slice format, or as a segmented 3D image, and a particular bodily structure identified. The identified structure coordinates are registered, if necessary, with respect to the patient when the patient is positioned for obtaining real-time fluoroscopic images during the treatment, and the bodily structure information is superimposed on the displayed fluoroscopic image. The treatment may be, for example, an electrophysiological (EP) ablation procedure for atrial fibrulation.03-26-2009
20100125193Closed-Loop Clot Lysis - The present invention provides procedures and systems that use a closed-loop approach for directing ultrasound energy at a clot while monitoring blood flow and/or liquification of the clot tissue so as to allow automated and/or manual adjustments to various treatment parameters.05-20-2010
20100125191MRI AS A THERAPEUTIC DEVICE - A method and device comprises a system alike a magnetic resonance imaging system (05-20-2010
20120035461METHOD FOR VISUALIZING A LYMPH NODE AND CORRESPONDINGLY EMBODIED COMBINED MR/PET APPARATUS - A method is disclosed for visualizing a lymph node in a volume section of an examination subject by way of a combined MR/PET apparatus and to a correspondingly embodied combined MR/PET apparatus. The method includes acquisition of PET data of the volume section by way of a positron emission detector in order to record on the basis of the PET data a metabolic activity per PET voxel within the predetermined volume section; acquisition of MR data of the volume section by way of a magnetic resonance system in order to record on the basis of the MR data a lymph-node-specific contrast per region of the predetermined volume section; and generation of an image as a function of the metabolic activity recorded per PET voxel and as a function of the lymph-node-specific contrast recorded per region, abnormal lymph nodes being visualized in the image as distinguishable from normal lymph nodes.02-09-2012
20100087727MULTI-MODALITY IMAGING APPARATUS AND METHOD FOR REGISTRATION OF THE MULTIPLE MODALITIES - Method to register multiple different imaging modalities warming an examination subject in a common image acquisition region of all imaging modalities, simultaneous or time-offset acquisition of at least one first image data set with a first imaging modality, simultaneous or time-offset acquisition of at least one second heat image data set with a second imaging modality, determining at least one item of heat information resulting from the warming of the examination subject is determined from each of the first image data set and the second heat image data set, and registration of the imaging modalities using the determined heat information.04-08-2010
20080269595Mapping of Vascular Perfusion Territories - Techniques, systems computer program products are disclosed for mapping of vascular perfusion territories by placing one or more blood vessels of the vascular perfusion territories in a tag condition and others in a control condition by applying a train of pseudo-continuous radio frequency tagging pulses. In addition, an encoding scheme is applied to fully invert or relax the blood vessels of the vascular perfusion territories. Also, a tagging efficiency is measured for each blood vessel based on the applied encoding scheme. Further, the vascular perfusion territories are separated by using the measured tagging efficiency in a decoding process.10-30-2008
20120108951Method and Apparatus for Determining the Position of a Surgical Tool Relative to a Target Volume Inside an Animal Body - The invention relates to a method for determining the position of a surgical tool relative to a target volume inside an animal body according to a pre-plan comprising the steps of i) obtaining a plurality of two-dimensional images of said target volume using imaging means, each 2D-image being represented by an image data slice I(x,y,z); ii) reconstructing from said plurality of image data slices I(x,y,z) a three-dimensional image of said target volume using transformation means, said 3D-image being represented by a volumetric image data array V(x,y,z); iii) displaying said three-dimensional image of said target volume to an user using displaying means.05-03-2012
20120108950BIOIMPEDANCE-ASSISTED PLACEMENT OF A MEDICAL DEVICE - A system and method for guiding a catheter or other medical device to a desired target destination within the vasculature of a patient via bioimpedance measurements is disclosed. The target destination in one embodiment includes placement of the catheter such that a distal tip thereof is disposed proximate the heart, e.g., the junction of the right atrium and superior vena cava. In one embodiment the method for guiding the catheter comprises introducing the catheter into a vessel of the patient, the catheter defining a lumen through which fluids can be infused into the vasculature of the patient. The catheter is advanced toward a target destination within the vasculature. A first impedance value based on intravascular detection of at least one electrical property related to a first tissue surface of the vessel is calculated to enable determination of the proximity of a distal end of the catheter to the target destination.05-03-2012
20120108949STAGED SENSING ADJUSTMENTS BY AN IMPLANTABLE MEDICAL DEVICE IN THE PRESENCE OF INTERFERING SIGNALS - An implantable medical device (IMD) receives an input associated with the presence of an environment having an external source that generates an interfering signal, such as an MRI device. The IMD adjusts a first set of one or more sensing parameters of a sensing module of the IMD in response to receiving the input associated with the presence of the environment. In this manner, the IMD operates in accordance with the adjusted sensing configuration in the presence of the interfering signal in an attempt to obtain a more detailed representation of the signal including noise caused by the interfering signal. The IMD analyzes the signals sensed using the first set of adjusted sensing parameters to determine if further adjustment is desired. If desired, the IMD adjusts a second set of one or more sensing parameters of the sensing module based on the analysis.05-03-2012
20120108948SYSTEM AND METHOD FOR COLLIMATION IN DIAGNOSTIC IMAGING SYSTEMS - A system and method for collimation in diagnostic imaging systems is provided. One collimation system includes a collimator for a radiation imaging detector having a plurality of adjustable segments and a plurality of collimator holes within each of the plurality of adjustable segments. The plurality of adjustable segments are configured to move independently of a detector to adjust a field of view of the collimator holes.05-03-2012
20110201919Radiotherapy and imaging apparatus - Radiotherapy apparatus comprises a source of radiation mounted on a chassis, the chassis being rotatable about a rotation axis and the source being adapted to emit a beam of radiation along a beam axis that intersects with the rotation axis; a patient support, moveable along a translation axis; a set of magnetic coils located on either side of the beam, for establishing a magnetic field at the point of intersection, spaced from that point along a first direction; the translation axis, the rotation axis, and the first direction being substantially parallel; and further comprising a multi-leaf collimator fixed in its orientation with respect to the source of radiation, the multi-leaf collimator comprising a plurality of elongate leaves disposed with their longitudinal directions substantially aligned with the first direction and movable in that direction between a withdrawn position in which the leaf lies outside the beam, an extended position in which the leaf projects across the beam and a plurality of intermediate positions therebetween.08-18-2011
20120130225MEDICAL DIAGNOSTIC DEVICE AND METHOD FOR DIAGNOSING - The invention relates to a medical diagnostic device (05-24-2012
20120035463AUTOMATED ANATOMY DELINEATION FOR IMAGE GUIDED THERAPY PLANNING - When delineating anatomical structures in a medical image of a patient for radiotherapy planning, a processor (02-09-2012
20090088623MOTION COMPENSATED IMAGE-GUIDED FOCUSED ULTRASOUND THERAPY SYSTEM - An image-guide therapy system comprises a thermal treatment device (e.g., an ultrasound transducer) configured for transmitting a therapeutic energy beam, and The system further comprises an imaging device (e.g., a magnetic resonant imaging (MRI) device) configured for acquiring images of the target tissue mass and the thermal treatment device. The system further comprises a controller configured for controlling thermal dose properties of the thermal treatment device to focus the energy beam on a target tissue mass located in an internal body region of a patient, and a processor configured for tracking respective positions of the thermal treatment device and the target tissue mass in a common coordinate system based on the acquired images. The system may optionally comprise a display configured for displaying the acquired images.04-02-2009
20090088624Methods and Apparatus for Diagnosing and Treating Aneurysms - A method of developing a diagnosis and prognosis for an aneurysm in order to determine a procedure for treating the aneurysm. The method includes determining a first diameter of a blood vessel at a first location proximal to an aneurysm, and determining a second diameter of the blood vessel at a second location. The second location incorporates at least a portion of the aneurysm. Next, the ratio of the second diameter to the first diameter is calculated. And, a prognosis of the aneurysm, and a determination of the treatment for the aneurysm, may then be determined based on the ratio.04-02-2009
20080208036Combined radiation therapy and magnetic resonance unit - The invention relates to a combined radiation therapy and magnetic resonance unit. For this purpose, in accordance with the invention a combined radiation therapy and magnetic resonance unit is provided comprising a magnetic resonance diagnosis part with an interior, which is limited in radial direction by a main magnet, and a radiation therapy part for the irradiation of an irradiation area within the interior, wherein at least parts of the radiation therapy part, which comprise a beam deflection arrangement, are arranged within the interior.08-28-2008
20110172517METHOD FOR DETERMINING INFORMATION USED AS THE BASIS FOR CALCULATING A RADIOTHERAPY TREATMENT PLAN AND COMBINED MAGNETIC RESONANCE IMAGING/PET DEVICE - A method for determining information used as the basis for calculating a radiotherapy treatment plan. In at least one embodiment, the method includes essentially simultaneous capture of PET data and magnetic resonance imaging data using a combined magnetic resonance imaging/PET device and determination of at least one magnetic resonance imaging data set and at least one PET data set from the data; and determination of a distortion-corrected magnetic resonance imaging data set and an attenuation data set from the magnetic resonance imaging data, whereby PET data is taken into consideration during the distortion correction and/or during the determination of the attenuation data set.07-14-2011
20100099974System for Generating a Multi-Modality Imaging Examination Report - A system processes medical report data associated with different types of imaging modality devices to provide a composite examination report. An acquisition processor in the system acquires multi-modality medical imaging examination report data for examinations performed on a patient by different types of imaging modality device. A report processor processes acquired multi-modality medical imaging examination report data items by, in response to predetermined selection riles, selecting between individual data items in the acquired multi-modality medical imaging examination report data items to provide a single individual data item for incorporation in a composite report. The report processor maps individual data items including the single individual data item in the acquired multi-modality medical imaging examination report data items to corresponding data fields in a composite report data structure in memory in response to predetermined mapping information. An output processor outputs data representing the composite report to a destination device.04-22-2010
20120271149INSERT DEVICE FOR ENHANCING PET AND MRI IMAGES - Insert devices that include a RF surface coil and gamma-ray photon detector array for enhancing PET and MRI images produced from integrated PET-MRI scanners are disclosed. Integrated PET-MRI scanners that include such insert devices as well of methods for scanning an object by use of such devices are also disclosed.10-25-2012
20090299170Magnetic resonance scanner with PET unit - A magnetic resonance scanner including a PET unit includes a magnet system and a gradient system having a patient bore. In at least one embodiment, the magnet system and the gradient system are each split by an azimuthal gap and the PET unit is disposed within the gap.12-03-2009
20120289816SURGICAL ACCESS ASSEMBLY AND METHOD OF USING SAME - A surgical access assembly and method of use is disclosed. The surgical access assembly comprises an outer sheath and an obturator. The outer sheath and obturator are configured to be delivered to an area of interest within the brain. Either the outer sheath or the obturator may be configured to operate with a navigational system to track the location of either within the brain. Once positioned at a desired location, the obturator is removed, leaving a distal end of the outer sheath adjacent an area of interest, and creating a working corridor. Interrogation of the area of interest may be performed to evaluate a disorder and/or abnormality, as well as evaluate treatment regimes. Interventional devices may also be introduced to the area of interest, as well as a variety of treatments.11-15-2012
20130218000MRI Coil For Imaging Of The Breast And Thoracic Area - The present invention provides a novel MRI coil configuration for breast cancer imaging in preparation for radiation therapy planning and treatment. Both an adjustable anterior and posterior coil sets are described. The coil sets are supported and configured so as not to affect the accurate and repeatable positioning of the patient and breasts. The coil sets are removable so that they can be extracted before radiation therapy treatment commences.08-22-2013
20080249396Method And Apparatus For Determining Indications Helping The Diagnosis Of Orthopedical Diseases - Apparatus for determining indications helping the diagnosis of orthopedic diseases comprising a section detecting and acquiring signals from a body under examination or from a part thereof wherein the detecting section is a unit detecting images by nuclear magnetic resonance and it is integrated in a section for processing acquired images as regards image data and/or resonance signals, which processing section defines, from image data and/or resonance signals, values of one or more different numerical parameters indicating the presence or absence of an orthopedic disease and/or a measure of the evolution condition of said orthopedic disease.10-09-2008
20080275331DETECTING TEMPERATURE AND PROTEIN DENATURATION DURING THERMAL THERAPY - In one aspect, in general, a method is provided for detecting temperature and protein denaturation of a tissue during thermal therapy. The method includes generating a plurality of MR pulse sequences that include a first group of pulse sequences and a second group of pulse sequences, and receiving a plurality of response signals that include a first and second group of response signals in response to the first and second groups of pulse sequences, respectively. A first information associated with a degree of protein denaturation of the tissue is determined based on the first and second groups of response signals. A second information associated with a temperature of the tissue is determined based on at least some of the plurality of response signals.11-06-2008
20080275330Mri Guided Ultrasound Therapy Apparatus - This invention provides a MRI guided ultrasound therapy apparatus. It comprises a static field magnet adapted to apply a static magnetic field in an magnetic resonance volume at a predetermined disposition; at least one ultrasound energy applicator adapted to apply energy within an energy application zone at a predetermined disposition; and The mechanical positioning means for moving said ultrasound energy applicator to position the applicator so that the energy application zone intersects said magnetic resonance volume within said region of the subject. In that apparatus, the static field magnet is open at both ends or open at side. The sided open is upward or downward and the mechanical positioning means of this ultrasound energy applicator is close to and is located outside of this sided open. This invention reduces the space limitation for the mechanical positioning means of the ultrasound transducer. Meanwhile, the non-magnetic requirement on the mechanical positioning means become less greatly and particularly the problem of interference from magnetic field produced by working current of the transducer power cord to MRI system can be solved.11-06-2008
20120296197Therapeutic Apparatus - A therapeutic apparatus comprising a high intensity focused ultrasound system (11-22-2012
20120296195APPARATUS AND METHOD FOR DETECTION AND MONITORING OF ELECTRONICAL ACTIVITY AND MOTION IN THE PRESENCE OF A MAGNETIC FIELD - The invention generally provides a method of detecting or monitoring the characteristics (including change over time) of at least one electrical indicator of the function of a tissue in a biological organism in the presence of a magnetic field. Preferably, the magnetic field is generated by a magnetic resonance imaging (MRI) scanner. The method preferably also comprises one or more steps of detecting or monitoring sources of unwanted signal, and compensating for, or avoiding the unwanted signal. Unwanted signal includes signals arising in part due to the presence of the magnetic field, and/or directly measuring such unwanted signals for the purposes of avoidance of or compensation for the unwanted signals. Preferably, the method also enables detecting motion of the subject during the performance of the method steps discussed in the preceding two paragraphs.11-22-2012
20090118609Method and system for performing ablation to treat ventricular tachycardia - A system and method of treating tachycardias and similar syndromes by the use of catheter ablation of tissue is described. A computed tomography (CT)-like image of the heart is obtained and processed to segment the various types of tissue. Papillary muscle areas are identified and displayed differently from the other nearby tissues so that the muscles can be avoided during treatment to avoid or minimize damage to the muscles during ablation treatment. Electrophysical data and scar tissue may also be identified in the image, which may be of the endoscopic type. The position of the catheter may be displayed as a synthetic image on the endoscopic view.05-07-2009
20080287772Motion Compensation in PET Reconstruction - Method and apparatus motion compensation in Positron Emission Tomography (PET) imaging. PET and Magnetic Resonance Imaging (MRI) are performed simultaneously and the latter is used to determine motion of the subject during the acquisition process. The PET image data are then corrected according to the subject motion so determined.11-20-2008
20100280355SYSTEM AND METHOD TO CHARACTERIZE CARDIAC FUNCTION - Systems and methods can quantify cardiac function. In one embodiment, a method (11-04-2010
20130218002MAGNETIC RESONANCE ELASTOGRAPHY FOR ULTRASOUND IMAGE SIMULATION - Ultrasound data is simulated using magnetic resonance (MR) elastography. MR elastography provides tissue characteristic information, such as elastic modulus, velocity, or stiffness. This tissue characteristic information indicates a density or viscosity of the tissue, allowing simulation of ultrasound data with MR acquired data. The same MR imaging system may be used to acquire the MR elastography and pre-operative anatomy information. The actual ultrasound information may be registered with simulated ultrasound information for registration of the actual ultrasound information with the MR anatomy information.08-22-2013
20120296196Method for assisting a person performing a minimally invasive intervention with a catheter involving a puncture of a septum and x-ray device - A method for assisting a person performing a minimally invasive intervention with a catheter involving a puncture of a septum, in particular of a heart, is proposed. A three-dimensional image data record is recorded showing an anatomical structure in the region of the septum. An item of septum information showing the position of the septum is determined in the image data record and additional information is derived from the position of the anatomical structure influencing or showing the selection of a puncture site. During the intervention, the fluoroscopic images of the region are continuously recorded and a current fluoroscopic image is displayed and superimposed with the septum information and/or the additional information based on a registration of the image data record with the fluoroscopic images.11-22-2012
20090264730MAGNETIC RESONANCE IMAGING (MRI) GUIDED ABLATION - Systems, methods, and other embodiments associated with tracking an ablative device and monitoring an ablation produced by the ablative device are described. One example method includes acquiring a magnetic resonance (MR) image of an ablative device inserted in a body and selectively controlling positioning of the ablative device based, at least in part on the MR image. The MR image may be continuously provided in real-time by an interventional MR imaging apparatus programmed to image using a tri-orthogonal plane sequence. The method may also include acquiring an MR image of an ablation performed by the ablative device, and selectively controlling the ablative device based, at least in part, on the MR image. The MR image may also be provided by the IMRI apparatus operating according to a tri-orthogonal plane sequence. In one example, the ablation may treat hypopharyngeal obstructive sleep apnea by reducing tongue base volume.10-22-2009
20080269593Method of integrated proton beam and therapeutic magnetic resonance therapy - A method of therapeutic treatment including the steps of modulated application of a time domain radiation beam to a therapeutic target; and providing a time domain application of a modulated magnetic resonance (MR) signal to the therapeutic target during the periods of application out-of-phase with energy peaks of the radiation beam.10-30-2008
20080269594APPARATUS AND METHOD FOR IMAGE ALIGNMENT FOR COMBINED POSITRON EMISSION TOMOGRAPHY (PET) AND MAGNETIC RESONANCE IMAGING (MRI) SCANNER - A phantom and method are provided for co-registering a magnetic resonance image and a nuclear medical image. The phantom includes a first housing defining a first chamber configured to receive a magnetic resonance material upon which magnetic resonance imaging can be performed in order to produce the magnetic resonance image. The phantom also includes three or more second housings configured to be attached to the first housing, where the second housings each define a second chamber configured to receive a radioactive material upon which nuclear imaging can be performed in order to produce the nuclear medical image and upon which the magnetic imaging can be performed in order to produce the magnetic resonance image. The first chamber has a volumetric capacity that is larger than a volumetric capacity of each second chamber.10-30-2008
20110270078METHODS AND SYSTEMS OF COMBINING MAGNETIC RESONANCE AND NUCLEAR IMAGING - An multi-modality imaging system for imaging of an object under study that includes a magnetic resonance imaging (MRI) apparatus and an MRI-compatible single-photon nuclear imaging apparatus imbedded within the RF coil of the MRI system such that sequential or simultaneous imaging can be done with the two modalities using the same support bed of the object under study during the imaging session.11-03-2011
20110270076METHOD FOR REMOVING NOISE OF PET SIGNAL USING FILTERING IN PET-MRI FUSION DEVICE AND PET SYSTEM IN PET-MRI FUSION DEVICE USING THE SAME - Provided is a method for removing noise of a positron emission tomography (PET) signal in a PET-magnetic resonance imaging (MRI) fusion device without using an MRI radio frequency (RF) shield that degrades image quality. The method includes: receiving a PET output signal from a PET-MRI fusion device and performing analog filtering by removing noise components due to an RF pulse frequency based on the relationship between the frequency of the PET output signal and a magnetic resonance (MR) RF frequency (Larmor frequency); and converting the filtered signal into a digital signal through sampling. The method allows acquisition of molecular-level images without declined performance of a PET detector in MRI environment.11-03-2011
20090030303AUDIENCE RESPONSE ANALYSIS USING SIMULTANEOUS ELECTROENCEPHALOGRAPHY (EEG) AND FUNCTIONAL MAGNETIC RESONANCE IMAGING (FMRI) - Neuro-response data including Electroencephalography (EEG), Functional Magnetic Resonance Imaging (fMRI) is filtered, analyzed, and combined to evaluate the effectiveness of stimulus materials such as marketing and entertainment materials. A data collection mechanism including multiple modalities such as, Electroencephalography (EEG), Functional Magnetic Resonance Imaging (fMRI), Electrooculography (EOG), Galvanic Skin Response (GSR), etc., collects response data from subjects exposed to marketing and entertainment stimuli. A data cleanser mechanism filters the response data and removes cross-modality interference.01-29-2009
20090030304Method for detecting a brain region with neurodegenerative change - A computerized method is disclosed for detecting a brain region with neurodegenerative change and also a brain region with vascular change in the brain of a patient and also an imaging arrangement suitable for this. In at least one embodiment, the method includes recording a first data record of the brain via positron emission tomography and a second data record of the brain via magnetic resonance imaging; reconstructing a PET image from the first data record and an MRI image from the second data record; identifying evidence for a brain region with vascular change in the MRI image; segmenting the MRI image into gray matter and white matter; identifying a brain region with neurodegenerative change in the PET image; and superposing the PET image and the segmented MRI image to determine whether the brain region with neurodegenerative change is present in gray matter or in white matter, the recording of the first data record and the second data record being carried out in quick succession without repositioning the patient or is even carried out simultaneously.01-29-2009
20110270077METHOD FOR REMOVING NOISE OF PET SIGNAL USING MODELING IN PET-MRI FUSION DEVICE AND PET SYSTEM IN PET-MRI FUSION DEVICE USING THE SAME - Provided is a method for removing noise of a positron emission tomography (PET) signal in a PET-magnetic resonance imaging (MRI) fusion device without using an MRI radio frequency (RF) shield that degrades image quality. The method includes: (a11-03-2011
20090005671Combined positron emission tomography / magnetic resonance imaging apparatus - A combined positron emission tomography/magnetic resonance imaging apparatus for imaging organs of an examination object in an examination space is disclosed, including a positron emission tomography apparatus having at least one radiation detector, and a magnetic resonance imaging apparatus having at least one gradient coil and a radio-frequency antenna device. In order to prevent mechanical oscillations being induced in the PET gantry by the gradient coil, at least one embodiment of the combined position emission tomography/magnetic resonance imaging apparatus is developed further in that a first molding is provided, whose surface coincides with the inner shell of the at least one gradient coil, and a second molding is provided, whose surface coincides with the outer shell of the radiation detector, the distance between the two shells being virtually constant over the circumference of the shells, and a vacuum seal being arranged in each case along at least a first and a second circumferential line such that a closed cavity is formed between the vacuum seals.01-01-2009
20110144476Integrated Surgical Sampling Probe - The present invention is directed to devices for collecting tissue samples from patients. The devices create tissue fragments which are then collected by aspiration. The devices include signal emitters that allow the exact position where a biopsy sample was obtained to be determined. In addition the invention includes methods for obtaining tissue samples using these devices.06-16-2011
20090259122DEVICE AND METHOD FOR MRI-GUIDED BREAST INTERVENTIONS - A method and apparatus for radially compressing bodily tissue and performing medical procedures from a selected one of a plurality of circumferential positions and angles, a selected one of a plurality of different elevations and elevational angles. Some embodiments include a tissue-compression fixture having members that are configured to be moved to radially compress bodily tissue such that each of a plurality of areas of biological tissue are exposed between the plurality of members, and wherein the fixture is compatible with use in an MRI machine in operation; an actuator having a receiver for a medical-procedure probe; and a computer system operatively coupled to the actuator to move the probe. The computer receives user commands, and based on the commands, moves the actuator to a selected one of a plurality of different positions around the tissue-compression fixture and then extends the probe into the patient.10-15-2009
20080319305Method for determining at least one pet parameter - A method is disclosed for determining at least one PET parameter for a PET examination in a combined magnetic resonance/PET scanner designed for isocentric measurement. In at least one embodiment, at least one acquisition time for the PET examination is determined as a PET parameter from magnetic resonance data, recorded for determining patient-specific examination parameters for a magnetic resonance examination, and/or from at least one patient-specific information value derived therefrom, and is displayed and/or used for controlling the scanner.12-25-2008
20080319304Assessment of Vascular Compartment Volume for PET Modelling - A method is described for acquiring and analysing the data produced by Positron Emission Tomography (PET), which method provides for an accurate estimation of vascular compartment volume, V12-25-2008
20090326365Medical robot for use in a MRI - A medical robot for use inside a magnetic resonance imager includes a horizontal motion assembly, a vertical motion assembly and a controller. The horizontal motion assembly includes a motion joint, an ultrasonic motor operably connected to the motion joint and an encoder operably connected to the ultrasonic motor. The motor and encoder are positioned proximate to the joint of the horizontal motion assembly. The vertical motion assembly is operably connected to the horizontal motion assembly and it includes a motion joint, an ultrasonic motor operably connected to the motion joint and an encoder operably connected to the ultrasonic motor. The motor and encoder are positioned proximate to the joint of the vertical motion assembly. The controller is operably connected thereto and is adapted to be powered off when the magnetic resonance imager is being used to collect images. A medical instrument assembly is connectable to the medical robot.12-31-2009
20090326364MRI compatible robot with calibration phantom and phantom - A medical robot for use inside an MRI includes a horizontal motion assembly, a vertical motion assembly and a controller. The horizontal motion assembly and the vertical assembly each includes a motion joint, an ultrasonic motor operably connected to the motion joint and an encoder operably connected to the ultrasonic motor. The motor and encoder are positioned proximate to the joint of the respective horizontal motion assembly and vertical motion assembly. Each motor has a cross section positioned in one of the axial and sagittal plane of the MRI. A medical instrument assembly is operably connectable to one of the moving joint of the vertical motion assembly. The controller is operably connected to the horizontal motion joint and the vertical motion joint and it is adapted to be powered off when the magnetic resonance imager is being used to collect images.12-31-2009
20090326363FUSED IMAGE MODALITIES GUIDANCE - An improved system and method (i.e. utility) for registration of medical images is provided. The utility registers a previously obtained volume onto an ultrasound volume during an ultrasound procedure to produce a multimodal image. The multimodal image may be used to guide a medical procedure, In one arrangement, the multimodal image includes MRI and/or MRSI information presented in the framework of a TRUS image during a TRUS procedure.12-31-2009
20090326362REGISTRATION OF MULTI-MODALITY IMAGES - A system for generating registered diagnostic images (12-31-2009
20110224534PET/MRI DEVICE, PET DEVICE, AND IMAGE RECONSTRUCTION SYSTEM - A PET/MRI device includes an MRI device that has a measurement port, a PET detector that can be inserted into the measurement port, and a mechanism that can slide the PET detector into and out of the MRI measurement port. Thereby, the PET/MRI device allows MRI measurement during PET measurement.09-15-2011
20090048506METHOD AND SYSTEM FOR ASSESSING BRAIN FUNCTION USING FUNCTIONAL MAGNETIC RESONANCE IMAGING - A system for assessing brain functioning uses neuropsychological assessments which are performed while a patient is within an fMRI scanning environment and while scanning is in process to detect the BOLD signals within the patient's brain. The system may be used to detect brain impairment and injuries which do not present tissue damage detectable using previous methods.02-19-2009
20110230754THERAPEUTIC APPARATUS - A therapeutic apparatus comprising: a magnetic resonance imaging system adapted for acquiring a set of magnetic resonance imaging data in an imaging zone, wherein the magnetic resonance imaging system comprises a means for generating a magnetic field, a guiding means adapted for guiding a beam of charged particles to a target zone within a subject such that the beam encloses an angle with the magnetic field lines of the magnetic field within the imaging zone, the angle being between 0 degrees and 30 degrees, wherein the imaging zone comprises the target zone, a zone determination means for determining the location of the target zone within the subject using the set of magnetic resonance imaging data.09-22-2011
20110230753Fluid circuits for temperature control in a thermal therapy system - A system and method for fluid control in a thermal therapy system is disclosed. A fluid circuit permits passage of a fluid through a fluid circuit, including into and out of a treatment zone so as to cool or heat or maintain a temperature in said treatment zone at or near a desired temperature. The temperature is sensed at a point in the circuit between a discharge of a fluid pump and the treatment zone. MRI based thermometry of tissue in the treatment zone is accomplished in some aspects. Furthermore, a desired temperature may be programmably set to a given value or within a band of values using a processor and a temperature controller. In some aspects, leakage of fluid from a patient or from the fluid control system is captured by a leak-proof member to protect imaging and treatment equipment from damage.09-22-2011
20120078082MRI THERMOMETRY COMBINED WITH HYPERPOLARISATION DEVICE USING PHOTONS WITH ORBITAL ANGULAR MOMENTUM - A magnetic resonance examination system comprises an RF-system for inducing resonance in polarised dipoles and receiving magnetic resonance signals from an object to be examined. A thermometry module dervies a temperature distribution of the object to be examined from the magnetic resonance signals. The magnetic resonance examination system further comprises a photonic-based hyperpolarisation device with a photonic source for emitting electromagnetic radiation, a moder converter, such as a phase hologram to impart orbital angular momentum to the electromagnetic radiation and va spatial filter to select from the phase hologram a diffracted photonic beam endowed with orbital angular momentum for polarising the dipoles via transferred orbital angular momentum.03-29-2012
20120078081DEVICE, SYSTEM, KIT OR METHOD FOR COLLECTING EFFLUENT FROM AN INDIVIDUAL - The present invention relates to a device, method, system and kit for receiving effluent from an individual. In an alternative embodiment, the present invention is directed to a device, method, system and kit for collecting effluent from an individual during a medical or diagnostic procedure including but not limited to, imaging or viewing one or more sections of an individual's gastrointestinal tract. In another alternative embodiment, the effluent is collected in a hollow area in order to prevent the effluent form contaminating a component, device or apparatus used in connection with the medical or diagnostic procedure.03-29-2012
20120078080Remotely Controlled Catheter Insertion System - A system for remotely controlling the positioning within the body of a patient of an elongated medical device optionally having a control handle, comprises a robotic system and a remote controller configured to control the robotic device. The robotic system comprises a handle controller; a sled member coupled to the handle controller, the sled member being configured to position the medical device within the body of the patient; and a sled base configured to advance the sled member towards the body of a patient, the sled bed being coupled to a sterile barrier effective to maintain sterility inside the sled base. A medical device introducer is effective to guide the elongated medical device into a patient's body.03-29-2012
20090253980METHOD AND APPARATUS FOR DETERMINING THE EFFECTIVENESS OF AN IMAGE TRANSFORMATION PROCESS - A method for determining the effectiveness of an image transformation process includes acquiring a four-dimensional (4D) image data set, sorting the 4D image data set into separate field-of-view bins using a temporal gating system generating a plurality of deformation vectors using the sorted 4D image data set, and using the plurality of deformation vectors to generate a transformation effectiveness value that is representative of the effectiveness of the image transformation process. The method further includes acquiring a respiratory signal, calculating a power spectrum of the respiratory signal, calculating a power spectrum for each of the plurality of deformation vectors, and comparing the power spectrum of the respiratory signal to the power spectrum of the plurality of deformation vectors to generate the transformation effectiveness value.10-08-2009
20090221903Magnetic resonance device having a pet unit - In a magnetic resonance device having a PET unit for acquiring positron emission tomography data and a gradient coil, the PET unit includes a carrier tube on which at least one PET detector is arranged. In at least one embodiment, the carrier tube is arranged inside the gradient coil and is displaceably mounted in such a way that access to the PET detector is made possible by its displacement. This allows easy access to the PET detector during maintenance activities.09-03-2009
20090247859METHOD AND APPARATUS FOR MR-GUIDED BIOPSY - The subject invention pertains to a method and apparatus for MR-guided biopsy. The subject invention can be applied to, for example, prostate biopsy. In a specific embodiment, the subject invention can provide a mechanical tool for stabilizing the patient in prone position and to guide a biopsy needle into defined targeted lesions in the prostate gland. The patient can lay prone in the MRI. The subject apparatus can guide an MR-visible, sterile needle sleeve, which can have a hollow tube filled with contrast media, through the anus onto the inner wall of the colon. Due to the visibility of the contrast media in the sleeve, the apparatus can be guided to the exact position. The sleeve can incorporate a tube within the contrast media filled sleeve to insert the biopsy needle and to push this needle forward into the prostate. The subject apparatus can utilize various mechanical means to stereotactically move the needle or needle sleeve in various directions.10-01-2009
20100261994INTEGRATION OF VERY SHORT ELECTRIC PULSES FOR MINIMALLY TO NONINVASIVE ELECTROPORATION - The present invention provides methods, devices, and systems for in vivo treatment of cell proliferative disorders. The invention can be used to treat solid tumors, such as brain tumors. The methods rely on non-thermal irreversible electroporation (IRE) or supra-poration to cause cell death in treated tumors. In embodiments, the methods comprise the integration of ultra-short electric pulses, both temporally and spatially, to achieve the desired modality of cell death.10-14-2010
20120095321Systems and Methods for Reducing Interference in a Dual Modality Imaging System - A magnetic resonance (MR)-positron emission tomography (PET) device dual modality system includes a dual modality detector system, conductors, and a PET processing device. The dual modality detector system includes a plurality of PET detector device having a framing recovery device and PET detectors, and an MR detector device having a magnetic resonance (MR) receiver. The conductors are electrically connected to the PET detectors. The PET processing device transmits modulated timing and frame synchronization signals to the PET detectors via the conductors and the framing recovery device. The frame synchronization signal is missing one or more framing signals, thereby reducing a spectral radiation of the conductors that causes interference to the MR receiver of the MR detector device. The framing recovery device detects the timing and frame synchronization signals and recovers the one or more missing framing signals.04-19-2012
20100185080MAGNETIC RESONANCE GUIDED CANCER TREATMENT SYSTEM - A system and method are provided for treatment of cancer, comprising: a focusable energy source for targeting a region of interest in a human or animal body to achieve hyperthermia in the region of interest; and a magnetic resonance imaging unit arranged to monitor at least one physical parameter related to oxygenation level spatially in and around the region of interest. The physical parameters may be one or more of partial oxygen pressure (pO07-22-2010
20110060211SYSTEMS AND METHODS FOR TOMOGRAPHIC IMAGING IN DIFFUSE MEDIA USING A HYBRID INVERSION TECHNIQUE - The invention relates to systems and methods for tomographic imaging in diffuse media employing a fast reconstruction technique. A hybrid Fourier approach is presented that enables the fast tomographic reconstruction of large datasets. In certain embodiments, the invention features methods of in vivo fluorescence molecular tomographic (FMT) reconstruction of signals, reporters and/or agents (i.e., contrast agents or probes) in a diffusive medium (e.g., a mammalian subject). The method preserves the three-dimensional fluorophore distribution and quantitative nature of the FMT approach while substantially accelerating its computation speed, allowing FMT imaging of larger anatomies.03-10-2011
20080208035Device for superposed MRI and PET imaging - A device is disclosed for superposed magnetic resonance imaging and positron emission tomography imaging. The device includes a magnetic resonance imaging magnet which defines a longitudinal axis; a magnetic resonance imaging gradient coil arranged radially within the magnetic resonance imaging magnet; a magnetic resonance imaging RF coil arranged radially within the magnetic resonance imaging gradient coil; and a multiplicity of positron emission tomography detection units arranged in pairs opposite one another about the longitudinal axis. In at least one embodiment, the many positron emission tomography detection units are arranged radially within the magnetic resonance imaging gradient coil and can be inserted into the device and can be removed from the device along the longitudinal axis. In at least one embodiment, a carrier tube is provided having a multiplicity of pockets, which in each case extend along the longitudinal axis, for accommodating at least one positron emission tomography detection unit.08-28-2008
20100217111SYSTEM, METHOD AND FACILITY FOR REDUCING PEDIATRIC PATIENT ANXIETY DURING MEDICAL DIAGNOSTIC IMAGING PROCEDURES - A facility for performing a medical examination includes a room, a medical imaging system located in the room, and a plurality of elements installed on at least one of the room and the medical imaging system, the elements collectively creating a first theme that forms a physical environment at least partially surrounding a patient, wherein the theme is presented in a manner to reduce the level of patient anxiety and fear experienced by the patient being imaged. A medical imaging system is also described. A method of imaging a patient using the facility, a method of remodeling an existing facility, and a method of determining a theme to be used in a medical facility are also described.08-26-2010
20120172709MULTIMODALITY NUCLEAR IMAGING RECONSTRUCTION METHOD - A method for obtaining a high-resolution nuclear image of a biological object, which image is acquired by a nuclear detector inside an MRI system includes the steps of acquiring MRI information pertaining to a wide field of view; focusing a field of view of the nuclear detector to a small region that covers only the target region; obtaining a nuclear image of the small region; and using a priori information included in the MRI information to eliminate image artifacts in the nuclear image. An apparatus for performing the method and a data image formed by practice of the method is also included.07-05-2012
20100217112PET-MRI COMBINATION APPARATUS - Disclosed herein is a PET-MRI combination apparatus which can extend transaxial and axial fields of view (FOV) by transmitting an output signal from a photo sensor to the outside of an MRI bore using cable. The PET-MRI combination apparatus includes an MRI bore for capturing an MR image of an object. A PET detector is installed inside imaging space of the MRI bore, and is configured such that a plurality of scintillation crystal arrays, each having scintillation crystals arranged in a ring shape, is arranged in a longitudinal direction so as to extend a axial field of view (FOV). A PET circuit unit is installed outside the MRI bore to prevent the PET circuit unit from being influenced by a magnetic field in the MRI bore, and is configured to include a signal amplification circuit and a signal processing circuit. A cable is configured to connect the PET detector to the PET circuit unit.08-26-2010
20080208033MULTI-SLICE CEREBRAL BLOOD FLOW IMAGING WITH CONTINUOUS ARTERIAL SPIN LABELING MRI - This invention is a method for multi-slice CBF imaging using continuous arterial spin labeling (CASL) with an amplitude modulated control which is both highly effective at controlling for off resonance effects, and efficient at doubly inverting inflow spins, thus retaining the signal advantages of CASL versus pulsed ASL techniques.08-28-2008
20120130226Automated methods and systems for vascular plaque detection and analysis - Automated methods and systems for the detection and analysis of plaque in one or more regions of a patient's vasculature are described.05-24-2012
20120035459METHOD OF NONINVASIVE ELECTROPHYSIOLOGICAL STUDY OF THE HEART - Reconstructing electrograms, whose experimental registration requires an invasive access, by computational way on unipolar ECGs recorded at 80 and more points of the chest surface. On the set of surface electrocardiograms for each discrete moment of the cardiocycle, values of the heart electric field potential at points of ECG-recording are determined, and a value of the electric field potential at each point of the chest surface is calculated by interpolation. Based on data of any visualization methodology, boundaries of chest and lungs surfaces and of the heart epicardial surface are determined. Further, a continuation of the electric field potential over the whole chest surface up to the heart epicardial surface with taking into account differences in electroconductivity of large anatomical structures of the chest is performed by computational way based on solution of the Cauchy problem for the Laplace equation in a piecewise-homogenous medium.02-09-2012
20110112394NEUROMODULATION OF DEEP-BRAIN TARGETS USING FOCUSED ULTRASOUND - Disclosed are methods and systems for non-invasive deep brain or superficial neuromodulation for up-regulation or down-regulation using ultrasound impacting one or multiple points in a neural circuit to produce Long-Term Potentiation (LTP) or Long-Term Depression (LTD) to treat indications such as neurologic and psychiatric conditions. Ultrasound transducers are positioned by spinning them around the head on a track, as well as individually rotated or not, with control of direction of the energy emission, intensity, frequency, and phase/intensity relationships to targeting and accomplishing up-regulation and/or down-regulation. Alternatively the ultrasound transducers may be at fixed locations on the track. Use of ancillary monitoring or imaging to provide is optional.05-12-2011
20110112395MEASUREMENT DEVICE AND MEASUREMENT METHOD - A measurement device and measurement method make it possible to eliminate the load generated by stopping on a measurement subject that is moved among multiple magnetic field generating devices. The measurement device includes a first external magnetic field generating device that generates a magnetic field of a set size, a second external magnetic field generating device that generates a magnetic field of a size that differs from that of the magnetic field of the first external magnetic field generating device, a rotating table that causes the subject of measurement to pass in sequence through the magnetic fields of the first and second external magnetic field generating devices by causing the subject of measurement to move rotationally, and an OMRI measurement processing part and MRI measurement processing part that measures images such as functional images or structural images of the subject of measurement while it is being moved rotationally by the rotating table.05-12-2011
20130218001DOSIMETER, THERAPEUTIC APPARATUS, AND COMPUTER PROGRAM PRODUCT FOR MEASURING RADIATION DOSAGE TO A SUBJECT DURING MAGNETIC RESONANCE IMAGING - A dosimeter (08-22-2013
20120143043METHOD AND COMPOSITION FOR HYPERTHERMALLY TREATING CELLS - A method and composition for hyperthermally diagnosing and monitoring treatment of cells with photoacoustic sound and nanoparticles. The heat (temperature) and photoacoustic sound wave production inside the target tissue is measured. The desired temperature is achieved using a laser and photoacoustic imaging technique. Hyperthermia treatment of tissue applies a heat source to kill cells without protein denaturation. The hyperthermia treatment may further comprise platelet-derived treatment. The method introduces an encapsulated dye that is released at a selected temperature in the target site to indicate that a threshold temperature has been reached to hyperthermally treat the tissue. The temperature to which the target site is treated ranges from about 39° C. to about 58° C., and may last from about 5 seconds to about 30 minutes. The composition which can be a liposome composition encapsulating the dye can be introduced to the bloodstream to flow through the target site.06-07-2012
20120143042Ultrasound Methods, Systems and Computer Program Products for Imaging Fluids Using Acoustic Radiation Force - The ultrasound system includes a controller configured to communicate with an ultrasound transducer such that the ultrasound transducer emits a radiation force excitation ultrasound pulse from the ultrasound transducer that propagates through the region of interest and is sufficient to perturb a fluid in the region of interest; emits a first and second acoustic ultrasound pulse from the ultrasound transducer that propagates away from the ultrasound transducer, through a region of interest and produces respective first and second echo ultrasound signal that propagate from the region of interest to the ultrasound transducer; and receives a first and second data set responsive to the first and second respective echo signals at the ultrasound transducer. A decorrelation module is configured to identify a decorrelation region of decorrelated data that is decorrelated between the first and second data sets, and the decorrelation region indicates a presence of fluid in the region of interest.06-07-2012
20120143041Images Of Language-Sensitive Neurocircuitry As A Diagnostic For Autism - The disclosed subject matter provides on ore more imaging techniques during passive auditory stimulation to objectively provide a diagnostic indicator of ASD. These techniques include functional MRI (fMRI), diffusion tensor imaging (DTI) and tractography, and combinations thereof. In one embodiment, a method is disclosed that uniquely provides an objective (imaging) physiological technique to diagnose early autism and to monitor progress following therapeutic intervention.06-07-2012
20100198049ACTIVE MRI INTRAMYOCARDIAL INJECTION CATHETER WITH DEFLECTABLE DISTAL SECTION - A deflectable tip catheter that is safe and effective for use in a magnetic resonance imaging environment. The deflectable tip catheter is configured such that it includes a built-in antenna, such as a loopless antenna or a loop antenna. The built-in antenna permits the deflectable tip catheter to be actively tracked and/or visualized. Depending upon the specific configuration of the deflectable tip catheter, the catheter may be tracked and/or visualized as a single unit, it may be tracked and/or visualized separate and independent of other components or instruments associated with the catheter, such as pull wires, injection needles, surgical instruments, and the like. The catheters described herein include injection type catheters and/or guidance type catheters.08-05-2010
20100198048MEDICINAL-SOLUTION ADMINISTRATION SYSTEM AND MEDICINAL-SOLUTION ADMINISTRATION CANNULA - A medicinal-solution administration system for feeding a medicinal solution to a mammal including a human includes a medicinal-solution feed device that feeds a medicinal solution, an observation device that includes an elongated observation probe and observes a diseased part to which the medicinal solution is administered, and a medicinal-solution administration cannula that has at least a part thereof implanted in a body. The medicinal-solution administration cannula guides the medicinal solution, which is fed from the medicinal-solution feed device, and the observation probe to the diseased part.08-05-2010
20100198047SMALL ANIMAL IMAGING CAPSULE AND BED SYSTEM - In a small animal imaging system (08-05-2010
20090209845METHOD TO OPTIMIZE INTERACTIVE PRODUCTS BASED ON THEIR FUNCTIONAL NEURAL IMPACT - Described herein are methods of optimizing an interactive media (e.g., a videogame) based on a brain activity criterion, as well as interactive media optimized or incorporating these methods. Brain activity may be measured using imaging techniques, such as an fMRI image of neural activity taken while a subject is using the technology. The optimization may be used to help the interactive media evoke desired behaviors or attitudes in subjects who have used the interactive media. For example, the interactive media described herein may be optimized to help facilitate behaviors or attitudes that are conducive to medical therapies, including compliance with medical treatments.08-20-2009
20090149735INTEGRATED EXTERNAL BEAM RADIOTHERAPY AND MRI SYSTEM - A radiation therapy system comprises a radiation source generating a beam of radiation and a magnetic resonance imaging apparatus. An interface acts between the radiation source and the MRI apparatus that permits irradiation to be performed simultaneously with imaging. The MRI apparatus and radiation source are coupled such that the system can be used in a rotation mode whereby the radiation source can irradiate a subject from basically any angle without reducing MRI image quality.06-11-2009
20090112082IMAGING DEVICE FOR MRI-GUIDED MEDICAL INTERVENTIONAL SYSTEMS - An MRI-guided interventional system includes a head support apparatus for engaging and securing the head of a patient, and a targeting frame configured to be secured to the body of a patient. The targeting frame includes a cooperating targeting cannula that is configured to guide placement of an interventional device through a burr hole in a patient's skull in vivo. The system includes an MRI-compatible camera positioned proximate to the head support apparatus, and an MRI-compatible imaging device having one end attached to the targeting frame to provide a local field of view of the burr hole, and an opposite end in communication with the camera. The system also includes a display output module coupled to the camera for receiving electrical signals therefrom and for displaying images corresponding thereto.04-30-2009
20110040169INTEGRATION OF MICRO AND MACRO INFORMATION FOR BIOMEDICAL IMAGING - Macroscopic imaging data, such as from a CT, MR, PET, or SPECT scanner, is obtained. Microscopic imaging data of at least a portion of the same tissue is obtained. To align the microscopic imaging data with the macroscopic imaging data, intermediate data is also obtained. For example, photographic data is acquired at an intermediary stage of a process of preparing tissue for microscopic scan. The macroscopic and microscopic data are registered to the intermediary photographic data. Once registered to the intermediary data, the spatial relationship between the macroscopic and microscopic data is known and may be used for imaging or quantification.02-17-2011
20110040170ENDOSCOPIC IMAGING PHOTODYNAMIC THERAPY SYSTEM AND METHODS OF USE - The invention provides an endoscopic imaging photodynamic therapy system (EIPS) for focused tissue ablation by illumination of a photosensitizer drug in a target tissue, said system comprising an endoscopic assembly, a real-time imaging component for locating the target tissue and monitoring the ablation intervention, a therapeutic light system and, optionally, a drug delivery module, wherein said imaging component comprises a flexible transducer with an operative channel for insertion of a flexible light guide of the therapeutic light system and, optionally, a flexible drug delivery catheter of the drug delivery module. This EIPS may be used in various medical applications where tissue ablation is required and photodynamic therapy may be applied, in particular, in the treatment of extrauterine pregnancy (EUP).02-17-2011
20090105580CHOOSING VARIABLES IN TISSUE VELOCITY IMAGING - The invention provides methods and systems for reducing noise in myocardial tissue velocity imaging such as ultrasound Doppler imaging or MRI. By adjusting recording factors and choosing apparatus settings and/or image analysis parameters in a systematic and consistent way, the quality of e.g. strain or strain rate imaging can be drastically improved. The invention reduces the noise by choosing values of variables, which lead to reduced or minimal beat-to-beat (BBV) variations in the imaged quantity such as average velocity, strain, strain rate or displacement or time derivatives of these.04-23-2009
20090105581ULTRASOUND IN MAGNETIC SPATIAL IMAGING APPARATUS - The present invention provides apparatus and methods for acquiring ultrasound measurements representing biosignals from a subject located in the strong magnetic field of a spatial imaging device. The invention includes ultrasound probes having minimal magnetic parts and an ultrasound signal pre-amplifier being shielded by a barrier or barriers from the strong magnetic field of a spatial imaging device such as an MRI, PET, or CT scanner. Most preferably, the ultrasound probe produces ultrasound waves in the frequency range of approximately 2.0 MHz to 2.5 MHz. The ultrasound probe may include no electronic components and contains minimal magnetic or ferromagnetic parts. The elements for acquiring and analysing ultrasound waves may be located in separate rooms from the imaging device. The invention provides a method of taking ultrasound measurements in quick succession with measurements of a spatial imaging device to provide a more informative understanding of the physiology of the subject.04-23-2009
20100217113CABLE MANAGEMENT SYSTEMS FOR MRI SYSTEMS AND RELATED METHODS - The disclosure describes cable management systems that provide adjustable lengths of cables that connect to various electronic medical or surgical tools. The systems can reduce the lengths of loose or hanging cables and define routes that preventing cross-over, looping and/or bunching of loose lengths of long cables.08-26-2010
20100312097Hybridized optical-MRI method and device for molecular dynamic monitoring of in vivo response to disease treatment - An apparatus for providing physiological information from an organism in disease diagnosis and treatment monitoring, for use in an MRI instrument. The apparatus operates on the concept of hybridized magneto-optical sensitivity. The MRI includes an MRI scanner and a controller for controlling the MRI scanner. The MRI scanner provides a magnetic field of at least 0.5T. The apparatus further includes a front end built of non-magnetic components, comprising light guides for illuminating a region of interest (ROI) and for collecting light emitted at said ROI; and a back-end comprising a light source for injecting light into said light guides; a light detector for receiving light collected at said ROI; and a processing and control unit for processing said light collected at said ROI.12-09-2010
20130137964MR GAMMA HYBRID IMAGING SYSTEM - A pendant breast imaging system that operates with a MRI system and which allows a planar gamma camera breast imaging system to be positioned away from the breast area while MRI imaging is occurring, and which then moves into breast imaging position after MRI imaging is complete, and which can again be removed from the breast area to allow intervention to occur is described. It may use various collimator or scintillator materials and designs.05-30-2013
20130137965SMALL TISSUE PROPERTY CHANGE DETECTION IN MAGNETIC RESONANCE GUIDED INTERVENTION - Small tissue property change detection is provided for magnetic resonance (MR) guided intervention. T1 changes from before and after treatment are compared. The comparison identifies locations of possible change. The comparison is performed for different times, one before and one after a zero-crossing of a signal intensity time curve. Due to the characteristics of the T1 mapping, common locations from the different times will have reversed contrast. Clustering and this reversal are used to distinguish the treatment region from noise.05-30-2013
20100312092Method and system for vascular elastography - The method for vascular elastography comprises: i) obtaining a sequence of radio-frequency (RF) images including pre-tissue-motion and post-tissue-motion images in digital form of a vessel delimited by a vascular wall; the pre-tissue-motion and post-tissue-motion images being representative of first and second time-delayed configuration, of the whole vessel; ii) partitioning both the pre-tissue-motion and post-tissue-motion images within the vascular wall into corresponding data windows; approximating a trajectory between the pre- and post-tissue-motion for corresponding data windows; and using the trajectory for each data window to compute the full strain tensor in each data window, which allow determining the Von Mises coefficient. The method can be adapted for non-invasive vascular elastography (NIVE), for non-invasive vascular micro-elastography (MicroNlVE) on small vessels, and for endovascular elastography (EVE).12-09-2010
20100331666SYSTEM FOR EMBOLIZING A TARGET SITE IN A BODY BY APPLICATION OF AN EXTERNAL ENERGY - A vaso-occlusive device is introduced in a cavity of a patient's vasculature, such as an aneurysm, after which an external energy source, such as a MRI machine is activated to heat the vaso-occlusive device to assist in forming a thrombus or embolism within the treatment site, to release and/or activate a diagnostic or therapeutic agent carried by the vaso-occlusive device, and/or to fuse together portions of the vaso-occlusive device to help stabilize the device in a three-dimensional shape.12-30-2010
20100331665METHOD FOR ABSORPTION CORRECTION OF PET DATA AND MR-PET SYSTEM - An apparatus is disclosed for combined magnetic resonance tomography and positron emission tomography imaging which is designed for recording PET image data of a person under examination from an examination area. In at least one embodiment, the apparatus includes a scanning unit, embodied to scan a prespecified area of the person under examination and based on the scanning, to determine a contour of the person under examination for the prespecified area; and a processing unit, embodied, based on the contour determined, to carry out an absorption correction of PET data which has been recorded from the prespecified area of the person under examination. A method is also disclosed.12-30-2010
20110034800ESTIMATION OF ALIGNMENT PARAMETERS IN MAGNETIC-RESONANCE-GUIDED ULTRASOUND FOCUSING - A magnetic-resonance-guided focused ultrasound system may be calibrated by generating ultrasound foci using ultrasound transducers, establishing coordinates of the foci and of magnetic-resonance trackers associated with the transducers, and determining a geometric relationship between the trackers and the transducers.02-10-2011
20110034801System for Processing Angiography and Ultrasound Image Data - A system provides a single composite image including multiple medical images of a portion of patient anatomy acquired using corresponding multiple different types of imaging device. A display processor generates data representing a single composite display image including, a first image area showing a first image of a portion of patient anatomy acquired using a first type of imaging device, a second image area showing a second image of the portion of patient anatomy acquired using a second type of imaging device different to the first type. The first and second image areas include first and second markers respectively. The first and second markers identify an estimated location of the same corresponding anatomical position in the portion of patient anatomy in the first and second images respectively. A user interface enables a user to move at least one of, (a) the first marker in the first image and (b) the second marker in the second image, to correct the estimated location so the first and second markers identify the same corresponding anatomical position in the portion of patient anatomy.02-10-2011
20110040172MEDICAL SYSTEM COMPRISING A PERCUTANEOUS PROBE - The percutaneous probe, made in MRI-compatible materials, comprises: a body percutaneously inserted into the tissue of a patient's body organ (02-17-2011
20110040171IMAGE GUIDED HIGH INTENSITY FOCUSED ULTRASOUND TREATMENT OF NERVES - A method for using high intensity focused ultrasound (HIFU) to treat neurological structures to achieve a desired therapeutic effect. Depending on the dosage of HIFU applied, it can have a reversible or irreversible effect on neural structures. For example, a relatively high dose of HIFU can be used to permanently block nerve function, to provide a non-invasive alternative to severing a nerve to treat severe spasticity. Relatively lower doses of HIFU can be used to reversibly block nerve function, to alleviate pain, to achieve an anesthetic effect, or to achieve a cosmetic effect. Where sensory nerves are not necessary for voluntary function, but are involved in pain associated with tumors or bone cancer, HIFU can be used to non-invasively destroy such sensory nerves to alleviate pain without drugs. Preferably, ultrasound imaging synchronized to the HIFU therapy is used to provide real-time ultrasound image guided HIFU therapy of neural structures.02-17-2011
20110178391SYSTEM AND METHOD FOR ULTRASOUND THERAPY TREATMENT - A system and method for treating tissue, such as treating prostate diseases, using an ultrasound therapy system. An ultrasonic applicator (07-21-2011
20110245656Arterial spin labeling MRI-based correction factor for improving quantitative accuracy of blood flow and volume images - Arterial spin labeling MRI is used to provide a patient specific correction factor to correct a image provided by a non-ASL imaging modality (e.g., DSC MRI). More specifically, a first blood flow image is taken using the non-ASL imaging modality, and a corresponding second blood flow image is taken with ASL. Some or all of the voxels in the first image are selected according to a predetermined selection method. A correction factor (CF) is computed to be the ratio of second image BF to first image BF averaged over the selected voxels. Thus, CF is the average of ASL/non-ASL blood flow over the selected voxels. This correction factor is applied to all voxels of an image equally, but can differ from patient to patient. This correction can be applied to one or more non-ASL blood flow images.10-06-2011
20090082659MEDICAL EXAMINATION APPARATUS - The invention relates to a medical examination apparatus, in particular an MR apparatus. Known MR apparatus have a cavity for accommodating the patient to be examined that offers only a limited space for the patient. The limited space may lead to claustrophobic reactions jeopardizing the result of a measurement. According to the invention a mirror (03-26-2009
20120035460MOVABLE MAGNET FOR MAGNETICALLY GUIDED CATHETER - A catheter is disclosed having a flexible tubing with a proximal end and a distal end. The catheter comprising at least one movable magnet provided within the distal end of the flexible tubing. A control mechanism is operable to selectively activate the at least one movable magnet from the proximal end of the flexible tubing. The at least one movable magnet is responsive to an external magnetic field to position and guide the distal end of the flexible tubing within a body of a patient.02-09-2012
20100217114MAGNETIC RESONANCE THERMOMETRY METHOD - A method for reducing errors in the measurement of temperature by magnetic resonance, for use in magnetic resonance imaging-guided HIFU equipment, includes acquiring an MR phase image, as a reference image, before heating an area to be heated with the HIFU equipment; acquiring another MR phase image, as a heated image, during or after the heating by the HIFU equipment; and calculating the temperature change in the heated area according to said heated image and said reference image; and making compensation to said temperature change according to the change in the magnetic field caused by the position change of an ultrasonic transducer in said HIFU equipment. The method can reduce significantly the temperature errors resulting from the position changes of the ultrasonic transducer.08-26-2010
20110087090RADIATION THERAPY SYSTEM WITH REAL TIME MAGNETIC RESONANCE MONITORING - A radiation therapy system comprises: a radiation therapy subsystem (04-14-2011
20110087089MULTIPLE MODALITY COMPUTER AIDED DIAGNOSTIC SYSTEM AND METHOD - A diagnostic system having an image loader including a processor for processing multiple modality images, at least one of the multiple modality images being a mammogram image, the processing including generating diagnostic information based on a computer aided diagnostic tool and an image viewer simultaneously displaying the multiple modality images.04-14-2011
20110087088COMPUTER-ASSISTED IDENTIFICATION AND TREATMENT OF AFFECTED ORGAN TISSUE - Computer-assisted processes are disclosed for using nuclear medicine image studies (e.g. PET or SPECT), preferably in combination with anatomic image studies (e.g., CT or MRI), to identify and quantify regions of affected organ tissue (e.g., myocardial infarcts), and to calculate doses of stem cells or other therapy to deliver to such regions. The resulting (static) image data showing the affected tissue may also be integrated with live (moving) image data, such as a fluoroscopy image, during a subsequent interventional procedure to generate a hybrid image showing the real time location of an injection catheter relative to the affected tissue.04-14-2011
20100191095PROCESS, DEVICE AND SYSTEM FOR REDUCING THE ARTIFACTS THAT AFFECT ELECTROPHYSIOLOGICAL SIGNALS AND THAT ARE DUE TO ELECTROMAGNETIC FIELDS - A method for collecting and a device for sensing at least one electrophysiological signal, as well as to a system including at least one such device. The device for sensing at least one electrophysiological signal from a living subject subjected to at least one electromagnetic field, includes elements, such as electrodes, which are placed on the subject for the physical acquisition of at least one electrophysiological signal and at least elements for the pre-processing of the at least one sampled electrophysiological signal. The sensor device (07-29-2010
20090048507Method and apparatus for imaging functional and electrical activities of the brain - A method and an apparatus for imaging functional and electrical activities of the brain are disclosed. In order to allow improved relative positional determination of the epileptogenic focus with reference to the EEG electrodes, a positron emission tomography measurement using at least one radiation detector, and a magnetic resonance imaging measurement using at least one coil for generating a basic magnetic field, at least one gradient coil and a radio-frequency antenna device are undertaken in at least one embodiment. In addition, in at least one embodiment an electroencephalography measurement using a plurality of electrodes for acquiring spatial and temporal changes of the electrical activities of the brain and a computed tomography measurement using at least one x-ray source and at least one x-ray detector are carried out. By way of an evaluation apparatus in at least one embodiment, a spatial correlation between the computed tomography measurement and the magnetic resonance imaging measurement is undertaken, so as to result in registration between the electroencephalography measurement and the positron emission tomography measurement.02-19-2009
20110152666TARGETED THERMAL TREATMENT OF HUMAN TISSUE THROUGH RESPIRATORY CYCLES USING ARMA MODELING - The present application discloses a technique for targeting therapeutic thermal energy to human tissue that is subject to displacement during a respiratory cycle using ARMA modeling. It discloses using an ARMA treatment of MRI tracking data of salient features of the tissue of interest to predict the spacial position of the portion of the tissue to be treated and using this prediction to guide the application of the thermal energy. It also discloses that this technique is particularly useful when the tissue of interest undergoes elastic deformation in a respiratory cycle and high energy focused ultrasound (HIFU) is used to ablate diseased tissue such as a cancerous tumor.06-23-2011
20120245452IMPLANTABLE DEVICE - An implantable electromedical device, having a detection unit for capturing possible device-impairing effects, a control unit, which is connected to the detection unit, a diagnostic and/or treatment unit, and a test unit, of which the test unit is designed to test the diagnostic-treatment unit, and to output test results for storage, of which the diagnostic and/or treatment unit includes sensor units and/or treatment delivery units as components and is designed to record physiological parameters and/or bring about delivery of a treatment, and of which the control unit is designed to actuate the test unit for testing the diagnostic-treatment unit.09-27-2012
20100063383CATHETER FOR MAGNETIC RESONANCE GUIDED PROCEDURES - A catheter for magnetic resonance (MR) guided procedures comprising: a catheter body having a lumen for accommodating an intravascular device; a magnetic coupling component in the catheter body, the magnetic coupling component being designed to magnetically couple with a conductive length on the intravascular device, the magnetic coupling resulting in a signal; the catheter having a connection to deliver the signal to a processor.03-11-2010
20110178387Method For Recording And Evaluating PET Data Recorded At The Same Time as Magnetic Resonance Data Using A Combined Magnetic Resonance/PET Apparatus, And A Combined Magnetic Resonance/PET Apparatus - A method is disclosed for recording and evaluating PET data recorded at the same time as magnetic resonance data using a combined magnetic resonance/PET apparatus, wherein in the context of a pulse sequence for recording the magnetic resonance data a magnetic resonance recording facility, including at least one gradient coil and at least one high-frequency coil, is activated. In at least one embodiment, the method includes recording the PET data and assigning the recorded PET data after the recording time point to at least two data groups assigned to a predetermined operating state of the magnetic resonance recording facility; for each data group, determining a measure of similarity of the PET data contained therein to the PET data as a whole and/or to PET data of at least one further data group, whereby if the measure of similarity is below a threshold value, the PET data of the data group is rejected and/or further evaluated separately.07-21-2011
20110178390Novel needle driver for magnetic resonance elastography - The present invention is directed toward an acoustic, piezoelectric, electric, electro-mechanical or pneumatically driven surface drum driver, in mechanical engagement with a biopsy or acupuncture needle device and a method for its use for diagnosis of small e.g. 100 microns, tumors via the production of magnetic resonance elastographic images (MRE), without artifact production, in a magnetic resonance imaging (MRI) machine. In a second embodiment, the invention is directed toward an acoustically, pneumatically, piezoelectrically, electrically and/or electro-mechanically driven acupuncture needle, useful for simulating manual single-needle acupuncture treatments via a non-manually manipulated acupuncture needle; and further to a device and process for determination, using twin pneumatically driven surface drivers, of organ stiffness, e.g. brain stiffness, which can be quantified so as to be useful in elucidating and quantifying brain cognitive state, e.g. normal, mild cognitive impairment (MCI) or Alzheimer's dementia (AD).07-21-2011
20110178389FUSED IMAGE MOLDALITIES GUIDANCE - An improved system and method (i.e. utility) for registration of medical images is provided. The utility registers a previously obtained volume (s) onto an ultrasound volume during an ultrasound procedure to produce a multimodal image. The multimodal image may be used to guide a medical procedure. In one arrangement, the multimodal image includes MRI information presented in the framework of a TRUS image during a TRUS procedure.07-21-2011
20090216109MRI Compatible Vascular Occlusive Devices and Related Methods of Treatment and Methods of Monitoring Implanted Devices - Implantable aneurysm-sac treatment devices include an implantable coil body configured and sized to reside in a sac of an aneurysm. The body has an inductance and capacitance. The capacitance is selected so that the coil resonates at a Larmor frequency of a predefined magnetic field strength.08-27-2009
20100056898Objective Methods of Estimating Age of Animals and Carcasses - An age of an animal or animal carcass is estimated using a measurement or measurements of physical properties of the animal or carcass. A correlation between at least one physical property or characteristic and the animal's age is determined. A measurement of the at least one physical property or characteristic is made using non-invasive technology. An estimated age is then determined comparing the measured at least one property to the correlation of property and age.03-04-2010
20100056899METHOD AND APPARATUS FOR MULTIMODAL IMAGING - The apparatus and imaging method of the present invention incorporates and permits the use of a single technology to combine MR, SPECT and PET in awake animal imaging studies.03-04-2010
20110152667MRI gradient field detector - A device and a method are disclosed for detecting electromagnetic fields, in particular, fields occurring in magnetic resonance tomography (MRT) or magnetic resonance imaging (MRI) tests. An implantable medical device (IMD), contained in a hermetically sealed housing, includes a control unit, a programming coil, and a communication unit, wherein the communication unit, together with the programming coil, is designed to allow communication between an external programming device and the IMD by utilizing alternating electromagnetic fields, and further comprising a detection unit for MRT interference fields, characterized in that the detection unit is designed in such a way that voltage profiles induced in the programming coil and originating from a pulsed alternating electromagnetic field of the MRT (gradient field) are detected, and a corresponding MRT detection signal is transmitted from the detection unit to the control unit, if communication with a programming device is not detected at the same time.06-23-2011
20110082362IMAGE-MONITORING METHOD FOR ELECTROPORATION TREATMENT AND AS ASSOCIATED IMAGE-MONITORING APPLIANCE - An image-monitoring method for an electroporation treatment with an electroporation appliance is provided. The electroporation appliance comprises at least two treatment electrodes and an image-monitoring appliance. At least one image monitoring measurement is performed by the image-monitoring appliance after the administration of a contrast agent and after the electroporation treatment.04-07-2011
20110098554Monitoring of convection enhanced drug delivery - A method for determining a response of a tissue to a destructive treatment is disclosed. The method comprises providing magnetic resonance images of the tissue, and using the magnetic resonance images for determining the response of the tissue to the destructive treatment. Also disclosed is a method for monitoring convection during direct convective interstitial infusion using a pharmaceutical composition which comprises a therapeutic agent and an MRI contrast agent.04-28-2011
20120035465Methods and systems of combining magnetic resonance and nuclear imaging - A multi-modality imaging system for imaging of an object under study, e.g., a whole body or parts of the body of animals such as humans, other primates, swine, dogs, or rodents, that includes a magnetic resonance imaging apparatus and a cadmium zinc telluride (CZT)-family semiconductor, single-photon imaging apparatus within a magnetic field produced by the magnetic resonance imaging apparatus such that sequential or simultaneous imaging can be done with the two modalities using the same support bed of the object under study in the same, uninterrupted imaging session.02-09-2012
20120035464CONTROL APPARATUS FOR CONTROLLING A THERAPEUTIC APPARATUS - A control apparatus (02-09-2012
20110077502BIO-MEDICAL UNIT AND SYSTEM WITH ELECTROMAGNETIC POWER HARVESTING AND COMMUNICATION - A medical system includes a transmitter unit, a bio-medical unit, and a receiver unit. The transmitter unit generates a magnetic resonance imaging signal and a downstream electromagnetic communication signal. The transmitter unit then modulates the downstream electromagnetic communication signal on the magnetic resonance imaging signal. The bio-medical unit receives the modulated magnetic resonance imaging signal and recovers, therefrom, the downstream electromagnetic communication signal. The bio-medical unit converts the downstream electromagnetic communications signal into downstream information. The bio-medical also converts upstream information into an upstream electromagnetic communication signal. The receiver unit receives the modulated magnetic resonance imaging signal and the upstream electromagnetic communication signal. The receiver unit then recovers the magnetic resonance imaging signal from the modulated magnetic resonance imaging signal and the upstream information from the upstream electromagnetic communication signal.03-31-2011
20110082363METHOD AND SYSTEM FOR PERFORMING BIOPSIES - A method and system for performing biopsies can include an imaging system (190) for obtaining diagnostic images of a target region (200); a tracking system (100); a probe (75) having a deployable biopsy needle for performing a biopsy procedure where the tracking system generates tracking information for at least one of the probe and the biopsy needle; an ultrasound imaging system (50) for obtaining ultrasound imaging of the target region; and a computer (150) in communication with the tracking system, the imaging system and the ultrasound imaging system. The computer can register the tracking system with the imaging system. The computer transfers a marking (500) of a biopsy site associated with the biopsy procedure from the ultrasound imaging to the diagnostic images based on the tracking information and the registration of the tracking system with the diagnostic images.04-07-2011
20110071381METHOD AND SYSTEM FOR LEADING MACROMOLECULE SUBSTANCES INTO LIVING TARGET CELLS - A method and system for leading macromolecule substances into target cells includes an image picking unit, an image merging unit, an injection unit, and an energy conversion module. The ultrasound energy conversion module comprises ultrasound transducers or tweeters. The image picking unit is used for picking up the three-dimensional (3D) and the 3D blood vessel photographic images of the tissue or organ where the target cells locate. The image merging unit is used for merging the 3D structure images into the 3D blood vessel photographic images, therefore choosing a blood vessel passage fully covering the target cells for transmitting the macromolecule substances. The injection unit is used for injecting liquid and transmitting the macromolecule substances to the target cells. The energy conversion module is used for exerting energy to activate the liquid to perform biological effects. The energy conversion module comprises ultrasound transducers or tweeters, thereby forming non-permanent holes in the cell membranes of the target cells. The macromolecule substances enter into the target cells through the non-permanent holes.03-24-2011
20110077505APPARATUS AND METHOD FOR IMAGING TISSUE - A device and method for imaging body tissue, the device comprising a catheter for accessing body cavities having a catheter end, the catheter end having there within an ionizing radiation source for emitting ionizing radiation; and at least one ionizing radiation detector for detecting ionizing radiation; and wherein preferably a signal is emitted by the ionizing radiation source, said signal comprising photons or electrons, said photons or electrons are reflected from the body tissue or provoke the body tissue to generate photons or electrons.03-31-2011
20110077504SYSTEM AND METHOD FOR ROBOTIC SURGICAL INTERVENTION - A system and method for image guided assisted medical procedures. The system and method may utilize MRI real time guidance during the above procedures.03-31-2011
20110077503Automatic MRI Quantification of Structural Body Abnormalities - Disclosed herein are methods and systems related to the body region analysis. In some forms, the analysis relates to body region abnormalities. In some forms, the methods and systems analyze and assign comparison scores (such as Z-score) to an image of a body region. In some forms, the comparison score is plotted voxel-by-voxel. In some forms, the computers and systems are adapted to execute the methods disclosed herein03-31-2011
20110071380Manual Instrumented Medical Tool System - A medical device is for use in association with a medical image of the gland or organ having a known reference point. The medical device comprises a structural frame, a horizontal joint, a vertical joint, a pan join, a tilt joint a medical instrument assembly and a control system. The medical device is positioned at a predetermined location relative to the medical image reference point. Each of the horizontal joint, the vertical joint, the pan joint and the tilt joint have a position sensor and are operably connected to the frame. The medical instrument assembly is operably connected to a sensor and to the horizontal joint, the vertical joint, the pan joint and the tilt joint. The control system is operably connected to the other elements whereby the control system determines the position of a predetermined location on the medical instrument assembly relative to the structural frame.03-24-2011
20110251478MOTION DETECTION IN MEDICAL SYSTEMS - In a medical system, at least one medically operative member (10-13-2011
20110009733NON-MAGNETIC MEDICAL INFUSION DEVICE - Liquid infusion apparatus includes non-magnetic materials in a pumping structure and drive motor therefore, and in a controller that supplies drive signals to the motor to facilitate convenient operation in intense magnetic fields without distorting the magnetic fields and without radiating objectionable radio-frequency interference.01-13-2011
20110009734IMAGE GUIDED HIGH INTENSITY FOCUSED ULTRASOUND TREATMENT OF NERVES - A method for using high intensity focused ultrasound (HIFU) to treat neurological structures to achieve a desired therapeutic effect. Depending on the dosage of HIFU applied, it can have a reversible or irreversible effect on neural structures. For example, a relatively high dose of HIFU can be used to permanently block nerve function, to provide a non-invasive alternative to severing a nerve to treat severe spasticity. Relatively lower doses of HIFU can be used to reversibly block nerve function, to alleviate pain, to achieve an anesthetic effect, or to achieve a cosmetic effect. Where sensory nerves are not necessary for voluntary function, but are involved in pain associated with tumors or bone cancer, HIFU can be used to non-invasively destroy such sensory nerves to alleviate pain without drugs. Preferably, ultrasound imaging synchronized to the HIFU therapy is used to provide real-time ultrasound image guided HIFU therapy of neural structures.01-13-2011
20110251479USE OF VENTRICULAR ENLARGEMENT RATE IN INTRAVENOUS IMMUNOGLOBULIN TREATMENT OF ALZHEIMER'S DISEASE - The present invention relates to the use of MRI monitoring of ventricular enlargement rate as an objective measure for the purpose of assessing disease progression in patients suffering from Alzheimer's disease and for the purpose of determining therapeutic effectiveness of a treatment regimen for Alzheimer's patients. Methods for treating Alzheimer's Disease and monitoring therapeutic effectiveness are provided.10-13-2011
20110251480Movable Integrated Scanner for Surgical Imaging Applications - A patient imaging system includes a patient support table, an MRI system including a cylindrical magnet and a PET system including positron detectors mounted in a ring. The magnet defines a cylindrical bore for receiving the patient on the table where the magnet is mounted for rotation about a vertical axis on a slew ring carried on rails allowing longitudinal movement. The PET ring is mounted in the bore for longitudinal movement. The quench tube for the magnet passes through the slew ring with a rotary union at the axis. The shielding covers include a fixed upper part and a lower part which rotates about the axis with the magnet. The magnet is arranged in a two or three room diagnostic configuration in which a holding bay houses the magnet and the diagnostic patients are organized in the three rooms each cooperating with the magnet bay as the magnet is rotated.10-13-2011
20110213239Combined Radiation Therapy and Magnetic Resonance Unit - The invention relates to a combined radiation therapy and magnetic resonance unit. For this purpose, in accordance with the invention a combined radiation therapy and magnetic resonance unit is provided comprising a magnetic resonance diagnosis part with an interior, which is limited in radial direction by a main magnet, and a radiation therapy part for the irradiation of an irradiation area within the interior, wherein at least parts of the radiation therapy part, which comprise a beam deflection arrangement, are arranged within the interior.09-01-2011
20100004528INTERVENTIONAL DEVICE FOR RF ABLATION FOR USE IN RF FIELDS - A interventional device for RF ablation for use in a RF electrical and/or magnetic field especially of a MR imaging system is disclosed, comprising an ablation catheter which is preferably trackable or can be guided or visualized in the image generated by the MR imaging system by means of a MR micro-coil (01-07-2010
20120123243CATHETER GUIDANCE OF EXTERNAL ENERGY FOR RENAL DENERVATION - An in vivo apparatus includes a flexible shaft having a proximal end, a distal end, and a length sufficient to access a patient's renal artery relative to a percutaneous access location. An energy guide apparatus is provided at the distal end of the shaft and dimensioned for deployment within the renal artery. An ex vivo apparatus includes an arrangement configured to localize the energy guide apparatus within the renal artery, and an energy source configured to direct ablative energy to target tissue located a predetermined distance from the localized energy guide apparatus. The target tissue includes perivascular renal nerve tissue adjacent the renal artery.05-17-2012
20120203096METHODS TO DIAGNOSE DEGENERATIVE DISC DISEASE USING PAIN STIMULI - Methods are provided that better describe, and localize the pain generator or suspected pain generator in and around spinal discs in relation to neck, back or leg pain so as to improve the diagnosis of degenerative disc disease. In some embodiments, there are methods for diagnosing a pain generator or a suspected pain generator in a patient suffering from back pain, the methods comprise causing painful stimuli at or near the pain generator or suspected pain generator in the patient suffering from back pain; labeling an inflammatory, vascular, neuronal, and/or metabolic pain marker at a location inside of or adjacent to an intervertebral disc in the patient suffering from back pain to increase an image of the pain marker with an imaging procedure; and imaging the labeled inflammatory, vascular, neuronal, and/or metabolic pain marker in a manner sufficient to diagnose the pain generator or suspected pain generator.08-09-2012
20110257511GENERAL INDUCTIVE HANDPIECE FOR ACTIVE DEVICES - A handpiece (10-20-2011
20110257512SUSCEPTIBILITY-BASED LOCAL FLOW DETECTION TO CONTROL MR-GUIDED ABLATION USING BALLOON DEVICES - An interventional instrument (10-20-2011
20110257509COORDINATION OF FUNCTIONAL MRI SCANNING AND ELECTRICAL STIMULATION THERAPY - Changes in electrical stimulation therapy delivered via a medical device are coordinated with Functional Magnetic Resonance Imaging (fMRI) scans. In one example, a medical device delivers electrical stimulation therapy to a patient in an MRI unit, where the medical device is configured to cycle electrical stimulation therapy between a plurality of stimulation states. An indication that the medical device will cycle the electrical stimulation therapy or has cycled the electrical stimulation therapy while the patient is in the MRI unit or being imaged by the MRI unit is generated, and an MRI scan of the patient via an MRI workstation is initiated based on the indication. In another example, a medical device detects activation of an MRI scan and automatically switches stimulation states based upon the detection of the MRI scan, such that the scan is associated with a particular stimulation state.10-20-2011
20110257510SYSTEM, METHOD AND APPARATUS FOR CARDIAC INTERVENTION WITH MR STROKE DETECTION AND TREATMENT - A system for the early detection and treatment of catheter-induced ischemic strokes includes a magnetic resonance system (10-20-2011
20110257508Device For Supporting, Scanning, Tomographically Displaying A Patient And Carrying Out An Intervention And Method For Determining The Spatial Relation Between Optical Recordings And Tomographic Displays - A device is disclosed for supporting, scanning, tomographically displaying a patient and carrying out an intervention. In at least one embodiment, for the device includes a computer system to: calculate the spatial position of at least one intervention channel in spatial relation to the patient couch and/or to the patient on the basis of previously obtained positional information on the at least one tomographic display of the patient; output the respectively current optical recordings of the patient on the patient couch online; and superpose the current optical recordings of the patient with a spatially adapted display of the intervention channel and/or intervention target point and/or an intervention instrument directed at the intervention channel. Moreover, a method is disclosed for determining the spatial relation between optical recordings and tomographic displays, with the aid of an adjustment phantom with at least three points in space that can be identified visually and at least three points in space that can be identified by the tomographic recording system, the mutual relative spatial positions of which are known.10-20-2011
20080208034Device, systems and methods for localized heating of a vessel and/or in combination with mr/nmr imaging of the vessel and surrounding tissue - Featured are devices, systems and methods for localized heating of a vessel as well as devices, systems and methods for MR/NMR imaging of a vessel while locally heating a portion of the vessel. More particularly featured are such devices, systems and methods for use when administering or delivering therapeutic agents including genes and/or drugs to the tissues of the vessel. Such a method includes positioning a thermal energy delivery device proximal a target site within the vessel of a body and activating the thermal energy delivery device so as to heat the target site thereby locally increasing a temperature of tissue at the target site. In further embodiments, the method includes introducing a therapeutic medium to the target site over a predetermined time period, and wherein said activating occurs at least one of before, during or after said step of introducing.08-28-2008
20120203098ULTRASOUND POWER SUPPLY FOR AN ULTRASOUND TRANSDUCER - An ultrasound power supply (08-09-2012
20080214928Method for Guiding Differential Diagnosis Through Information Maximization - A system and method for diagnosis and treatment decisions based on information maximization is disclosed. Utilizing patient information as well as clinical records from other patients can reduce the uncertainty in both diagnosis and treatment options. The information maximization may consider additional data such as risk, cost, and comfort in making a proper medical decision.09-04-2008
20080214929Method and device for imaging objects - A method for imaging objects is disclosed. In at least one embodiment, the method includes using a first and a second imaging method which differ at least in regard to the spatial resolution or sensitivity. Furthermore, in at least one embodiment, the method includes generating an overview image at least by the first or the second imaging method; simultaneously planning the measurement of the first and the second imaging method on the basis of the overview image; and simultaneously conducting the planned measurements of the first and the second imaging method. A device which conducts at least one embodiment of the method is also disclosed.09-04-2008
20120203097MAGNETIC RESONANCE IMAGING SYSTEM AND METHOD FOR DETECTING A GAS BUBBLE - A magnetic resonance imaging system (08-09-2012
20080255444Novel needle driver for magnetic resonance elastography - The present invention is directed toward an acoustic, piezoelectric, electric, electro-mechanical or pneumatically driven surface drum driver, in mechanical engagement with a biopsy or acupuncture needle device and a method for its use for diagnosis of small e.g. 100 microns, tumors via the production of magnetic resonance elastographic images (MRE), without artifact production, in a magnetic resonance imaging (MRI) machine. In a second embodiment, the invention is directed toward an acoustically, pneumatically, piezoelectrically, electrically and/or electro-mechanically driven acupuncture needle, useful for simulating manual single-needle acupuncture treatments via a non-manually manipulated acupuncture needle; and further to a device and process for determination, using twin pneumatically driven surface drivers, of organ stiffness, e.g. brain stiffness, which can be quantified so as to be useful in elucidating and quantifying brain cognitive state, e.g. normal, mild cognitive impairment (MCI) or Alzheimer's dementia (AD).10-16-2008
20110054300SURGERY SUPPORT DEVICE, SURGERY SUPPORT METHOD, AND COMPUTER READABLE RECORDING MEDIUM STORING SURGERY SUPPORT PROGRAM - Presentation of images showing with high resolution the state of a surgical field during surgery is realized with a simple configuration. When performing surgery, a three-dimensional model is generate based on MRI images of a patient captured prior to surgery, and three-dimensional coordinates of each location on a surface of the patient are measured by scanning a laser beam over the surface and detecting laser beam reflected therefrom, and correspondence is made with the MRI image for each location of the surface (frameless/markerless: steps 03-03-2011
20110263967ULTRASOUND BASED METHOD AND APPARATUS FOR STONE DETECTION AND TO FACILITATE CLEARANCE THEREOF - Described herein are methods and apparatus for detecting stones by ultrasound, in which the ultrasound reflections from a stone are preferentially selected and accentuated relative to the ultrasound reflections from blood or tissue. Also described herein are methods and apparatus for applying pushing ultrasound to in vivo stones or other objects, to facilitate the removal of such in vivo objects.10-27-2011
20100292564System and Method For Magnetic-Nanoparticle, Hyperthermia Cancer Therapy - A system and method is provided for performing and monitoring a magnetic nanoparticle hyperthermia process on a subject having received a dose of a magnetic nanoparticle configured to bind to tissue within a target area of the subject. A low-field MRI system is utilized having a static magnetic field and a radio frequency (RF) system configured to receive MRI data from the target area. A hyperthermia system is coupled to the low-field MRI system and configured to generate a hyperthermia excitation field configured to cause the magnetic nanoparticle to rotate at a lag with respect to a magnetic field experienced by the magnetic nanoparticle to cause a temperature increase in the target area. The MRI system is configured to acquire medical imaging data from the target area and reconstruct images therefrom indicating at least one of a spatial distribution of the nanoparticle in and a temperature of the target area.11-18-2010
20110118588Combination MRI and Radiotherapy Systems and Methods of Use - A combination MRI and radiotherapy system comprising: a) an MRI system for imaging a patient receiving radiotherapy, comprising a magnetic field source suitable for generating a magnetic field of strength and uniformity useable for imaging, capable of being ramped up to said magnetic field in less than 10 minutes, and ramped down from said magnetic field in less than 10 minutes; b) a radiation source configured for applying radiotherapy; and c) a controller which ramps the magnetic field source down to less than 20% of said magnetic field strength when the radiation source is to be used for radiotherapy, and ramps the magnetic field source up to said magnetic field strength when the MRI system is to be used for imaging.05-19-2011
20110118587OPTIMIZATION OF RF TRANSMIT AND GRADIENT MAGNETIC FIELD IMAGING USING RADIO FREQUENCY AND GRADIENT COILS - The invention provides various systems, machine readable programs and methods for performing imaging using a MR scanner. The MR scanner includes at least one local radio-frequency transmit coil and at least one local gradient coil. The local radio-frequency transmit coil(s) and local gradient coil(s) cooperate to define an imaging volume. The MR scanner further includes a control system for performing an imaging operation on a patient's anatomy disposed within the imaging volume. The control system permits a selective simultaneous increase of the gradient magnetic field strength and peak B1 field strength by substantially the same factor, f.05-19-2011
20100305425Medical System For Providing External Trigger Signal - There are disclosed embodiments for a medical system capable of providing an external trigger signal. The medical system comprises at least one of an ECG signal providing unit to provide an ECG signal indicative of an electrical change in a target object, a reference signal providing unit to provide at least one reference signal for triggering an operation of the medical system, and a medical image providing unit to provide a medical image of the target object. The medical system may further comprise a processor to form an external trigger signal using at least one of the ECG signal, reference signal and medical image. The medical system may further comprise a signal interface unit to transmit the external trigger signal to an external device coupled to the medical system.12-02-2010
20100324410METHOD OF DETERMINING THE POSITION OF A DEEP BRAIN STIMULATION ELECTRODE - The present invention relates to a method of determining the position of a deep brain stimulation (DBS) electrode which finds the position of the DBS electrode with respect to a deep brain target region, by using a first volume data set containing information on the deep brain target region and a second volume data set containing information on the DBS electrode implanted toward the deep brain target region, and which includes: a first step of generating a subvolume of the deep brain target region from the first volume data set, and also generating a subvolume of the DBS electrode from the second volume data set; and a second step of overlapping and displaying the subvolume of the deep brain target region and the subvolume of the DBS electrode.12-23-2010
20100179416Medical Systems and Methods - A prostate therapy system is provided that may include any of a number of features. One feature of the prostate therapy system is that it can access a prostate lobe transrectally. Another feature of the prostate therapy system is that it can image the prostate lobe transrectally. One feature of the prostate therapy system is that it can deliver condensable vapor into the prostate to ablate the prostate tissue. Methods associated with use of the prostate therapy system are also covered.07-15-2010
20090209844PATIENT BED FOR PET/MR IMAGING SYSTEMS - A hybrid imaging system and a patient bed for same are disclosed. The hybrid imaging system includes a magnetic resonance scanner and a second modality imaging system spaced apart from the magnetic resonance scanner by a gap. In some embodiments, the gap is less than seven meters. The patient bed is disposed at least partially in the gap between the magnetic resonance scanner and the second modality imaging system, and includes a linearly translatable patient support pallet aligned to be selectively moved into an examination region of the magnetic resonance scanner for magnetic resonance imaging and into an examination region of the second modality imaging system for second modality imaging. In some embodiments, a linear translation range of the linearly translatable pallet is less than five times a length of the patient support pallet along the direction of linear translation.08-20-2009
20100125192FOCUSED ULTRASOUND SYSTEM - A focused ultrasound system includes an ultrasound transducer configured to emit focused ultrasound energy toward a subject and a positioning system configured to position the ultrasound transducer to localize the focused ultrasound energy within a target location. The positioning system includes a drive apparatus to translate the ultrasound transducer along at least one axis of motion and a motor controller to control the drive apparatus. The focused ultrasound system also includes a control system connected to the motor controller that is programmed to receive imaging/location data from an imaging system, determine positional coordinates of the target location based on the imaging/location data, and register the positional coordinates of the target location with the positioning system. The positional coordinates are sent to the motor controller via an input signal to cause the motor controller to control the drive apparatus so as to translate the ultrasound transducer.05-20-2010
20090171185POSITIONING SYSTEM FOR THERMAL THERAPY - Systems and methods are provided for positioning a therapeutic device relative to a target displaced on a platform. A base member has a first track extending along a length of the platform for defining a first pathway for translating the therapeutic device relative to the target. A curved frame is slidably mounted on the base member through the first track. The curved frame has a second track along an interior wall of the curved frame for defining a second pathway for translating the therapeutic device relative to the target. A housing is disposed in the second track of the curved frame and configured to receive the therapeutic device. The housing is extendible at least along a radial direction of the curved frame for defining a third pathway for translating the therapeutic device relative to the target. Applications of the systems and methods may include image-guided thermal therapy.07-02-2009
20100121177Administering a therapeutic agent with more than one taggant - A system may include a means for administering a therapeutic agent to a subject; a means for administering a first pharmaceutically-acceptable taggant to the subject at least substantially concurrent with the therapeutic agent, the first pharmaceutically-acceptable taggant having a pharmacokinetic profile; and a means for administering a second pharmaceutically-acceptable taggant to the subject with the first pharmaceutically-acceptable taggant, the second pharmaceutically-acceptable taggant having a pharmacokinetic profile different from the pharmacokinetic profile of the first pharmaceutically-acceptable taggant.05-13-2010
20100121176Administering a therapeutic agent with more than one taggant - A system may include a means for administering a therapeutic agent to a subject; a means for administering a first pharmaceutically-acceptable taggant to the subject at least substantially concurrent with the therapeutic agent, the first pharmaceutically-acceptable taggant having a pharmacokinetic profile; and a means for administering a second pharmaceutically-acceptable taggant to the subject with the first pharmaceutically-acceptable taggant, the second pharmaceutically-acceptable taggant having a pharmacokinetic profile different from the pharmacokinetic profile of the first pharmaceutically-acceptable taggant.05-13-2010
20110137148Method and device comprising fused ultrasound and magnetic resonance imaging - A device and method for concurrently obtaining ultrasound and MRI image data are disclosed. A probe member comprises ultrasound imaging means at a first predetermined position on the probe member and an MRI coil at a second predetermined position on the probe member. An MRI imaging system having an MRI pulse sequence comprising an MRI image data acquisition period and an MRI pulse sequence time gap generates an MRI image data set. An ultrasound image data set is acquired only during the MRI pulse sequence time gap in which the operation of the ultrasound imaging means does not interfere with the MRI imaging operation.06-09-2011
20110137149NERVE TREATMENT SYSTEM - A method of treatment includes delivering an agent into a patient, and providing energy inside the patient so that the energy can interact with the agent to treat a nerve. A system for treatment includes a source of agent for delivery into a patient, and an energy source for providing energy inside the patient so that the energy can interact with the agent to treat a nerve.06-09-2011
20110137147MINIMUM TIME FEEDBACK CONTROL OF EFFICACY AND SAFETY OF THERMAL THERAPIES - A thermal treatment control system including an imaging device for specifying the geometry and/or location of the treatment target, a thermal energy element for applying a thermal treatment for the heating or cooling of a target tissue for therapeutic purposes, a thermal energy detecting element for detecting a measured tissue response to the thermal treatment and a feedback controller for a real-time modification of the intensity and spatial distribution of the thermal dose in order to achieve therapeutic efficacy over a minimum or reduced treatment time while satisfying treatment constraints imposed to limit damage to normal tissues.06-09-2011
20100305426POSITIONING SYSTEM AND METHOD OF POSITION DETECTING - A body-insertable apparatus has a resonance circuit for emitting a resonance magnetic field by being guided by a drive magnetic field received from the outside. An external device has: a drive coil driving unit for outputting a drive signal having a predetermined frequency; a drive coil for receiving the output drive signal and generating the drive magnetic field in a detection space; a sense coil for detecting the resonance magnetic field and outputting a detection signal; a position deriving unit for deriving position information of the resonance circuit by using the detection signal; a current detecting unit for detecting a current amplitude value of the drive signal input to the drive coil; and a drive magnetic field generation control unit for calculating an amplitude value of a drive signal which is output from the drive coil driving unit by using the current amplitude value, detecting the degree of stability indicating whether a sharp change occurs in the drive magnetic field on the basis of the calculated amplitude value, and controlling the position deriving unit on the basis of the detected degree of stability in the drive magnetic field detected.12-02-2010
20120071749SYSTEM AND METHOD FOR INTEGRATED BIOPSY AND THERAPY - A system and method for integrating diagnosis and treatment for internal tissues includes imaging (03-22-2012
20120150019MRI BY DIRECT TRANSVERSE HYPERPOLARIZATION USING LIGHT ENDOWED WITH ORBITAL ANGULAR MOMENTUM - A magnetic resonance system includes a main magnet (06-14-2012
20100191094Diagnostic delivery service - Systems, methods, and other modalities are described for (a) obtaining an indication relating to an emission module (which may be dangerous, e.g.) or its user (who may be untrained, e.g.) and for (b) configuring the module or causing an irradiation (for imaging, e.g.) in response to the indication.07-29-2010
20110190621Methods and Systems for Regional Synchronous Neural Interactions Analysis - Systems and methods for quantifying neurophysiologic activity of a subject. A set of subject data representing a time series of neurophysiologic activity acquired by each of a multiplicity of spatially distributed sensors arranged to detect neural signaling in the subject is received. A time series of data obtained from each of the sensors is associated with a corresponding neural population within the brain of the subject. Interaction sets among at least two neural populations in the brain of the subject are determined based on a statistical analysis of a plurality of time series of data from a corresponding plurality of sensors. A plurality of regional groupings of neural populations is stored, with each one of the plurality of regional groupings encompassing a plurality of neural populations having a predefined relationship. An aggregated representation of cross-regional interactions between the neural populations across a selected plurality of the regional groupings is produced based on a selected subset of the interaction sets.08-04-2011
20110263966Dissipation Device and MRI-Safe Catheter System - A dissipation device having a proximal end, which is located outside the body, and a distal end, which is suited in particular for elongate medical instruments, in particular electrophysiological catheters or temporary electrode leads, placed temporarily in the body. The dissipation device including a dissipation sleeve which extends from the proximal end to the distal end of the dissipation device, and a lumen which extends from the proximal end to the distal end, and in which the instrument can be displaceably guided, wherein the lumen is enclosed by the dissipation sleeve. The dissipation device is characterized in that the dissipation sleeve is composed, at least partially, of electrically conductive material, and/or the dissipation sleeve includes dissipation means composed of electrically conductive material and, therefore, the dissipation sleeve is designed to dissipate or divert electrical energy induced by electromagnetic radiation.10-27-2011
20110201920Radiotherapy and imaging apparatus - A radiotherapy system comprises a patient support, moveable along a translation axis, an imaging apparatus, comprising a first magnetic coil and a second magnetic coil, the first and second magnetic coils having a common central axis parallel to the translation axis, and being displaced from one another along the central axis to form a gap therebetween, the imaging apparatus being configured to obtain an image of a patient on the patient support, a source of radiation mounted on a chassis, the chassis being rotatable about the central axis and the source being adapted to emit a beam of radiation through the gap along a beam axis that intersects with the central axis, a multi-leaf collimator comprising a plurality of elongate leaves movable between at least a withdrawn position in which the leaf lies outside the beam, and an extended position in which the leaf projects across the beam, and a radiation detector mounted to the chassis opposite the source, the radiation detector having a plurality of detector elements aligned with the elongate leaves when projected onto an isocentric plane.08-18-2011
20110218423WEARABLE ULTRASOUND PROBE ASSEMBLY AND METHOD OF MANUFACTURING SAME - A wearable ultrasound probe apparatus includes a wearable membrane. An ultrasound transducer is also included that is integrated into the wearable membrane and configured to maintain a substantially consistent contact with a surface of an object to be imaged when the object has the wearable membrane disposed thereon.09-08-2011
20110218422ELECTRICAL LEAD FOR AN ELECTRONIC DEVICE SUCH AS AN IMPLANTABLE DEVICE - A lead for an electronic device which resists the induction of a current from an electromagnetic field external to said lead includes one or more pairs of adjacent segments of electrical wire, each of the pairs including a first segment of electrical wire and a second segment of electrical wire. The lead also includes one or more shielded RF chokes, wherein each of the shielded RF chokes is provided between the first segment of electrical wire and the second segment of electrical wire of a respective one of the one or more pairs of adjacent segments. Also, an implantable device that includes a generator for generating one or more electrical pulse and a lead as described for delivering the pulses to tissue within a patient's body. A method for making the described implantable device is also provided.09-08-2011
20110218421DEVICE AND METHOD FOR REDUCING THE HEART RATE OF A PATIENT, AND APPARATUS HAVING THE DEVICE - A device is disclosed for stimulating the trigeminal nerve of a patient in order to reduce the heart rate of the patient for recording image information from the heart of the patient. In at least one embodiment, the device includes at least one device for mechanical, electrical, magnetic, thermal, optical and/or chemical stimulation of the trigeminal nerve. Furthermore, at least one embodiment relates to an apparatus including at least one such device and a unit for registering the heart rate of the patient, which unit interacts with the device. Furthermore, at least one embodiment moreover relates to a method for reducing the heart rate of a patient in order to record image information from the heart of the patient, in which method the trigeminal nerve of the patient is stimulated by at least one such device in order to lower the heart rate of the patient.09-08-2011
20100016707IMAGING SYSTEM - A medical diagnostic system, the system comprising:01-21-2010
20110144475METHOD FOR A REGULATION OF A VASCULAR INTERVENTION, AND DEVICE TO REGULATE A VASCULAR INTERVENTION - In a method and apparatus to regulate a vessel intervention conducted with a vessel intervention unit, wherein an intervention region of the vessel intervention is at least partially imaged by means of an imaging monitoring unit, and a monitoring region to monitor the vessel intervention is selected, and the vessel intervention is at least partially automatically regulated in the intervention region dependent on at least one characteristic variable identified in the monitoring region.06-16-2011
20100010337Combined PET/MRI device, component and local coil - A combined PET/MRI device is disclosed. In at least one embodiment, the PET/MRI device includes an MRI unit for exciting nuclear spins in an examination volume and for receiving signals generated by the excitation in the examination volume, and a PET unit with a detector which surrounds the examination volume at least in part and is used for detecting radiation emanating from the examination volume, with, firstly, damping of the radiation emitted by the examination volume and, secondly, undesired interactions with electromagnetic fields of the MRI unit on the components of the PET/MRI device arranged between the examination volume and the detector being avoided due to the material properties and/or structural design of the components. Corresponding components such as, for example, patient couches, bearing or support apparatuses and local coils, are both MRI and PET compatible.01-14-2010
20090221902Ultrasound Treatment Center - Methods and apparatus for non-invasive patient treatment using ultrasound are disclosed. One method comprises administering to a patient a therapeutic agent, transmitting ultrasound and directing the ultrasonic energy at a region of interest of a patient, monitoring cavitation in and around the region of interest in real time, and controlling the ultrasonic transmitting device, based on the monitored cavitation, so that the ultrasonic energy is focused at the region of interest. Another method comprises determining the position of a region of interest in terms of spatial coordinates, storing or calculating an expected effect of therapeutic ultrasound on the region of interest, focusing ultrasound energy on the region of interest based on the spatial coordinates, measuring the effect of the ultrasound energy on the region of interest, comparing the measured effect with the stored or calculated effect, and providing an output of the comparison.09-03-2009
20120150017OPEN PET/MRI HYBRID MACHINE - A PET/MRI hybrid machine that combines a PET device with an MRI device, includes: an open PET device that has a PET field of view at least part of which is an open space accessible from outside; and an open MRI device that has an MRI field of view at least part of which is an open space accessible from outside, and the open space of the PET field of view and the open space of the MRI field of view are allowed to overlap each other at least in part. This makes it possible to simultaneously measure and image the same open space accessible from outside by the PET device and the MRI device, thereby acquiring functional information and morphological information at the same time.06-14-2012
20090024021Methods and Systems for Using Transcranial Magnetic Stimulation and Functional Brain Mapping for Examining Cortical Sensitivity, Brain Communication, and Effects of Medication - Transcranial magnetic stimulation is interleaved with functional brain imaging to examine cortex sensitivity and brain communication and to determine efficacy of medication.01-22-2009
20110306870THERAPEUTIC APPARATUS FOR TREATING A SUBJECT USING MAGNETIC NANOPARTICLES - A therapeutic apparatus for treating a subject comprising: a first heating means adapted for heating a first region of the subject, a first control means for controlling the power directed into the first region by the first heating means such that the power stays below a threshold value, a particle heating means adapted for heating magnetic nanoparticles within a second region of the subject using a time varying magnetic field, wherein the first region comprises the second region.12-15-2011
20100292563Optical MRI device - A dual modality imaging apparatus, comprising a magnetic resonance imaging (=MRI) system and a fluorescence molecular tomography (=FMT) system, for investigating a sample (11-18-2010
20120150016IMAGE GUIDED RADIATION THERAPY SYSTEM AND SHIELDED RADIO FREQUENCY DETECTOR COIL FOR USE THEREIN - A radiation therapy system includes a radiation source capable of generating a beam of radiation; a magnetic resonance imaging (MRI) apparatus comprising at least one radiofrequency detector coil; and an electrically grounded dielectric material between the radiation source and the radiofrequency detector coil for shielding the at least one radiofrequency detector coil from the beam of radiation. Also disclosed is a radiofrequency detector coil for a magnetic resonance imaging (MRI) apparatus sheathed at least in part by a dielectric material that is adapted to be electrically grounded.06-14-2012
20100174172MRI SYSTEM FOR UPRIGHT RADIOTHERAPY - An image-guided radiotherapy system including a magnet assembly operable to produce a horizontal imaging field in an imaging region, and a non-imaging field in a non-imaging region, a positioner operable to rotate an object in the imaging region about a generally vertical rotational axis, a magnetic resonance (MR) imager in communication with the horizontal imaging field, a collimator operable to collimate a generally horizontal radiation beam directed towards the object, and a radiation source operable to produce a radiation beam of charged particles substantially parallel to the non-imaging field in the non-imaging region.07-08-2010
20120010498OPERATION SUPPORTING DEVICE, METHOD, AND PROGRAM - Surgical operation supporting apparatus and method is disclosed in which based on a high-definition tomographic images of an operation site produced before surgery, a three-dimensional model of the operation site is generated, and a surface of the operation site is optically measured during the surgical operation, and further, first position information that represents a three-dimensional position of each of points on the surface is acquired. An unexposed portion of the operation site is measured with ultrasonic waves during the surgical operation, and second position information that represents a three-dimensional position of each of points in the unexposed portion is acquired. Based on the first position information and the second position information, displacement and distortion at a portion whose three-dimensional position is not known in the three-dimensional model is estimated to obtain an estimated result. The three-dimensional model is re-corrected by use of a finite element method and the estimated result.01-12-2012
20120004531Innately Multimodal Nanoparticles - A gold-coated iron oxide nanoparticle, method of making thereof, and method of using thereof is disclosed. The nanoparticle is substantially toxin free (making it clinically applicable), easily functionalized, and can serve as a contrast agent for a number of imaging techniques, including imaging a subject in at least two distinct imaging modes. Further, the nanoparticle is well-suited for therapeutic uses.01-05-2012
20110098555Auscultation apparatus, auscultation method, and medical examination and diagnostic device - An auscultation apparatus including an optical microphone is proposed. Optical microphones can reliably acquire sounds of the most disparate frequencies even in an environment permeated by electromagnetic fields, without influencing said fields. Such an optical microphone of an auscultation apparatus can be disposed inside a medical examination and diagnostic device during operation. Given a suitable arrangement, both the heart sounds and the respiratory sounds of a patient can be recorded and monitored already with just one optical microphone.04-28-2011
20120010499USE OF NANOPARTICLES FOR THE TREATMENT OF CANCER - The invention relates to the tracking of mesenchymal stem cells (MSCs) labeled with magnetic nanoparticles using magnetic resonance imaging (MRI) and the use of this method for the treatment of cancer.01-12-2012
20120310079MEDICAL APPARATUS INSTALLATION, AND METHOD FOR CONTROLLING A MEDICAL APPARATUS - In a medical apparatus and method, the apparatus installation has a placement device for a patient, into which placement device is integrated at least one electromechanical sensor. A signal evaluation device is supplied with the measurement signals generated with the at least one electromechanical sensor, for evaluation. The medical apparatus is connected with the signal evaluation device, and the medical apparatus acquires measurement signals that relate to breathing and/or cardiac activity of the patient with the at least one electromechanical sensor upon support of the patient on said placement device. Trigger signals are generated with the signal evaluation device based on the measurement signals which relate to breathing cycle and/or cardiac cycle of the patient. The operation of the medical apparatus is controlled based on the trigger signals.12-06-2012
20110166440DIAGNOSTIC IMAGING SYSTEM AND METHOD - The invention relates to a diagnostic imaging system. The system encompasses a plurality of scanning apparatuses (07-07-2011
20110166437RECEIVING SURFACE COILS USED DURING THERMAL ABLATION PROCEDURE - A magnetic resonance imaging system to be used over a target area of a subject includes first and second RF coils for receiving an RF signal from the subject. The first RF coil is fixed to a position device and movable over the target area of subject. The second RF coil is larger than the first RF coil and has a larger field of view than the first RF coil. The system further includes an image processing device programmed to process RF signals coupled from the first RF coil and the second RF coil to form an MRI image.07-07-2011
20110166439MEDICAL INSTRUMENT - The invention relates to a medical instrument that can be inserted into a human or animal body. The medical instrument includes an instrument body having at least one poor electrically conducting rod-type body made of a matrix material and non-metallic filaments. The medical instrument is characterized in that the rod-shaped body is doped with X-ray marker particles, and the medical instrument includes an MR-marker, or the instrument body includes an immobilized active MR marker in the surface area.07-07-2011
20110166438RF FIELD SHAPING AND ATTENUATION FOR EMAI INDUCTION ELEMENTS - An Electro-Magnetic Imaging (EMAI) System is presented. EMAI systems can include induction elements (e.g., an induction coil) configured to induce a target tissue to generate internally sourced ultrasounds. The induction elements can be shielded by one or more shielding elements to shape, or otherwise alter, an imaging field while attenuating radiated fields in a far zone. EMAI systems can further include a shield tuner to adjust shield parameters to achieved desired imaging or radiated field properties. A shielding element can be placed approximately one induction coil radius away from the coil to achieve suitably strong imaging field magnitudes while also achieving suitably weak radiated field magnitudes in a far zone. In some embodiments, acoustic sensors lack substantial shielding from the fields generated by the induction elements.07-07-2011
20120065494ENERGETIC MODULATION OF NERVES - A method to deliver focused ultrasound energy from a position outside a skin of a patient to a nerve surrounding a blood vessel, includes placing the patient on a table in a substantially flat position, moving a transducer into a position inferior to ribs, superior to an iliac crest, and lateral to a spine of the patient, maintaining the transducer at the position relative to the patient, and delivering focused ultrasound energy through the skin of the patient without traversing bone, wherein the direction of the focused ultrasound is directed from a lower torso to an upper torso of the patient.03-15-2012
20120065495NEEDLE BIOBSY IMAGING SYSTEM - Imaging techniques. Radiation is directed from a source onto a sample using an endoscope having cellular or subcellular resolution. The endoscope includes one or more fibers. The fibers have a proximate end and a distal end, and the distal end is lensless. A focal plane of the endoscope is substantially at a tip of the distal end. Radiation from the sample is directed onto a detector to diagnose or monitor the sample.03-15-2012
20120065493ENERGETIC MODULATION OF NERVES - A method to apply a nerve inhibiting cloud surrounding a blood vessel includes creating a treatment plan, wherein the treatment plan prescribes application of the nerve inhibiting cloud towards at least a majority portion of a circumference of a blood vessel wall, and applying the nerve inhibiting cloud towards the majority portion of the circumference of the blood vessel wall for a time sufficient to inhibit a function of a nerve that surrounds the blood vessel wall.03-15-2012
20120016226ENERGETIC MODULATION OF NERVES - A system to modulate an autonomic nerve in a patient utilizing transcutaneous ultrasound energy delivery includes a processor comprising an input for receiving information regarding energy and power to be delivered to a treatment region containing the nerve, and an output for outputting a signal, wherein the processor is configured to determine a position of a reference target from outside the patient to localize the nerve relative to the reference target, a therapeutic energy device comprising a transducer for delivering ultrasound energy from outside the patient, a controller to control an aiming of the transducer based at least in part on the signal from the processor, and an imaging system coupled to the processor or the therapeutic energy device.01-19-2012
20120116209HIGH MAGNETIC FIELD COMPATIBLE INTERVENTIONAL NEEDLE AND INTEGRATED NEEDLE TRACKING SYSTEM - An elongate device (e.g. a catheter) for interventional MRI has one or more passive LC-circuits (wireless markers) attached to its distal tip portion for position tracking. The LC-circuits comprise an inductor winding (05-10-2012
20120022363SYSTEM FOR DELIVERING CONFORMAL RADIATION THERAPY WHILE SIMULTANEOUSLY IMAGING SOFT TISSUE - A device and a process for performing high temporal- and spatial-resolution MR imaging of the anatomy of a patient during intensity modulated radiation therapy (IMRT) to directly measure and control the highly conformal ionizing radiation dose delivered to the patient for the treatment of diseases caused by proliferative tissue disorders. This invention combines the technologies of open MRI, multileaf-collimator or compensating filter-based IMRT delivery, and cobalt teletherapy into a single co-registered and gantry mounted system.01-26-2012
20120022362Data Processing Unit Integration for MR-PET Imaging - An integrated magnetic resonance (MR) and positron emission tomography (PET) system includes an MR scanner including a magnet that defines an opening in which a subject is positioned, a set of PET detectors disposed between the opening and the magnet, and a plurality of data processing units, each data processing unit being configured for communication with a respective one or more of the PET detectors of the set of PET detectors. Each data processing unit includes an RF shield housing, and the RF shield housings of the plurality of data processing units are disposed in a symmetrical arrangement relative to the opening.01-26-2012
20120022361Data Processing Unit Positioning in MR-PET Imaging System Integration - An integrated magnetic resonance (MR) and positron emission tomography (PET) system includes an MR scanner including a magnet that defines an opening in which a subject is positioned, a set of PET detectors disposed between the magnet and the opening, and a plurality of data processing units, each data processing unit being configured for communication with a respective one or more of the PET detectors of the set of PET detectors. The plurality of data processing units are positioned along a side of the MR scanner not having the opening.01-26-2012
20090076375Myocardial tissue ablation device for treatment of cardiac arrhythmias by ablation of myocardial tissue in a patient as well as associated catheter and associated method - The invention relates to a myocardial tissue ablation device for treatment of cardiac arrhythmias by ablation of myocardial tissue in a patient, with the myocardial tissue ablation device featuring a catheter which is embodied as an integrated unit with at least one myocardial ablation means and at least one imaging element based on optical coherence tomography and/or intravascular magnetic resonance imaging.03-19-2009
20120059242Hybrid MR/PET Scanner With Patient Table Split Cable Feed - A hybrid magnetic resonance (MR) and positron emission tomography (PET) imaging system reduces likelihood of artifact distortion in PET images attributable to MR local coil cables and connectors in the patient table. MR local coil cables coupling the MR scanner and the MR local coil connectors are oriented so that they are outside the scanner field of view when performing PET scans.03-08-2012
20100280354GUIDED PUNCTURING NEEDLE AND PUNCTURING GUIDING METHOD - A guide puncturing needle which is integratively used with a scanning and detecting device, such as CT, MRI or the like, and provides puncturing, biopsy, injection, implanting, and the physical diagnose and therapy, such as RF, microwave, freezing, laser and the like, and a puncturing guide method for applying the puncturing needle to puncture are provided. Since the guide puncturing needle is provided with a needle-entering angle guide means (11-04-2010
20100280356THERAPY SYSTEM WITH TEMPERATURE CONTROL - A therapy system comprises a therapy module to direct a therapeutic action to a target along successive trajectories in a target region that includes the target. A thermometry module is provided to measure temperature a measurement field and in particular to compute a thermal dose. A control module to controls the therapy module to apply the therapeutic action along the respective trajectories on the basis of the measured temperature and/or thermal dose. The successive trajectories are located in the target zone outward or inward relative to one another within the target zone. In particular the therapeutic action subsists in application a focused ultrasound beam to the target. Temperature measurement is done on the basis of magnetic resonance signals.11-04-2010
20120065492ENERGETIC MODULATION OF NERVES - A system for treatment includes a focused ultrasound energy source for placement outside a patient, wherein the focused ultrasound energy source is configured to deliver ultrasound energy towards a blood vessel with a surrounding nerve that is a part of an autonomic nervous system inside the patient, and wherein the focused ultrasound energy source is configured to deliver the ultrasound energy from outside the patient to the nerve located inside the patient to treat the nerve.03-15-2012
20110092800Methods for modifying electrical currents in neuronal circuits - A method for modifying neuronal activity in a subject with focused ultrasound pulses (“FUP”) is provided. Such a methods is applicable for research, treatment, and diagnosis of psychiatric, neurological, and neuroendocrine disorders whose biological mechanisms include neuronal circuits in the brain. The application of focused ultrasound pulses is generally via multiple ultrasound transducers that are housed in a cap worn by the subject. The application of FUP at different tone burst duration, total sonication duration, and pulse repetition frequency settings results in either the inducement of either an increase or decrease in neuronal activity.04-21-2011
20110092799Active implant medical device (AMID) and medical imaging scanner communications involving patient-specific AIMD configuration - A communications link between an active implanted medical device (AIMD) and a magnetic resonance imaging (MRI) machine enables an information exchange including data relating to a configuration of a lead of the AIMD as installed in the patient and/or an operational parameter limit of the MRI machine determined from the data. The data relating to the configuration of the lead in the patient may include a size and/or position of an effective loop area enclosed by the lead. The data relating to the configuration of the lead in the patient may include data corresponding to a pictorial representation, such as an x-ray of the patient having the AIMD, of the lead and at least part of the patient's body. An operation of the MRI machine may be stopped or a warning/alarm initiated if the operational parameter limit (e.g., maximum power limit of a gradient or RF field) determined from the data relating to the configuration of the lead in the patient is exceeded.04-21-2011
20120157822Inverse Imaging of Electrical Activity of a Heart Muscle - A method for providing a representation of the distribution, fluctuation and/or movement of electrical activity through heart tissue, said method comprising: obtaining an ECG of the heart comprising said tissue; obtaining a model of the heart geometry; obtaining a model of the torso geometry; relating the measurements per electrode of the ECG to the heart and torso geometry and estimating the distribution, fluctuation and/or movement of electrical activity through heart tissue based upon a fastest route algorithm, shortest path algorithm and/or fast marching algorithm.06-21-2012
20120071748SURGICAL ACCESS ASSEMBLY AND METHOD OF USING SAME - A surgical access assembly is disclosed. The surgical access assembly comprises an outer sheath and an obturator. The outer sheath is defined by an open distal end and an open proximal end and includes a hollow body portion therebetween. The obturator is defined by a distal end and a proximal end and the distal end further comprises a tapered distal tip member that terminates in a closed radiused distal tip. The obturator is configured to be received within the outer sheath such that the tapered distal tip member protrudes from the open distal end of the outer sheath when the obturator is in an introducing configuration.03-22-2012
20120071747USE OF VENTRICULAR ENLARGEMENT RATE IN INTRAVENOUS IMMUNOGLOBULIN TREATMENT OF ALZHEIMERS DISEASE - The present invention relates to the use of MRI monitoring of ventricular enlargement rate as an objective measure for the purpose of assessing disease progression in patients suffering from Alzheimer's disease and for the purpose of determining therapeutic effectiveness of a treatment regimen for Alzheimer's patients. Methods for treating Alzheimer's Disease and monitoring therapeutic effectiveness are provided.03-22-2012
20110066026RF COIL FOR USE IN MAGNETIC RESONANCE IMAGING IN INTEGRATED SPECT AND MR IMAGING - An apparatus and method for performing dual modality SPECT/MRI imaging on an object in combination with a whole-body MRI system includes a collimated nuclear radiation detector for receiving radiation from the object, and a radiofrequency MRI coil enveloping the object and interfaced with the collimated nuclear radiation detector. The MRI coil and collimated detector are arranged and configured for disposition within the whole-body MRI system.03-17-2011
20110066027Combined Imaging System with a Magnetic Resonance System and a UWB Radar - During operation of a combined imaging system with a magnetic resonance system and a UWB radar, a wireless signal transmission in conjunction with a patient monitoring system is to be enabled in a simpler and more cost-effective manner. To this end, the use of already existing components of the UWB radar is proposed for the wireless signal transmission. This makes it possible to dispense with an additional transmitting and/or receiving antenna for the wireless signal transmission.03-17-2011
20110105889NANOPARTICLE LABELING AND SYSTEM USING NANOPARTICLE LABELING - A nanoparticle labeling which is simultaneously usable in the combination of X-ray imaging with optical imaging and the combination of X-ray imaging and optical imaging with magnetic resonance imaging characterized by comprising core/shell type semiconductor nanoparticles having an average shell thickness of 0.1 nm or more but not more than 10.0 nm together with an X-ray sensitive material for the former combination, and core/shell type semiconductor nanoparticles having an average shell thickness of 0.1 nm or more but not more than 10.0 nm together with an X-ray sensitive material and magnetic particles for the latter combination.05-05-2011
20100094119METHOD AND EQUIPMENT FOR IMAGE-GUIDED STEREOTACTIC RADIOSURGERY OF BREAST CANCER - A method of treating a cancerous region in a breast of a patient comprising (i) imaging the breast in a three-dimensional coordinate system, (ii) stereotactically determining the location of the cancerous region in the breast, (iii) optionally determining the volume of the entire cancerous region to be treated, and (iv) while maintaining the breast in a three-dimensional coordinate system that is identical to or corresponds with the three-dimensional coordinate system used in (i), noninvasively exposing the cancerous region of the breast of the patient to a cancer-treatment effective dose of radiation; and equipment for use in such a method.04-15-2010
20100094120PREDICTING EFFICACY OF PSYCHIATRIC TREATMENT - Methods and systems are described for determining, in a patient that suffers from a mood disorder (e.g., depression), a propensity of the patient to manifest reduced symptoms or levels of indicators of the mood disorder in response to a psychiatric treatment. This can involve determining levels of a marker (e.g., a metabolite) indicative of a brain bioenergetic state of the patient that is predictive of whether the patient will response favorably to an antidepression treatment. Such bioenergetic state markers, tending to normalize in response to antidepression therapy, can include, e.g., a pH, a magnesium level, and a phosphorus level. Brain levels of such markers can be determined by, e.g., 04-15-2010
20120316426IMAGE GUIDED HIGH INTENSITY FOCUSED ULTRASOUND TREATMENT OF NERVES - A method for using high intensity focused ultrasound (HIFU) to treat neurological structures to achieve a desired therapeutic effect. Depending on the dosage of HIFU applied, it can have a reversible or irreversible effect on neural structures. For example, a relatively high dose of HIFU can be used to permanently block nerve function, to provide a non-invasive alternative to severing a nerve to treat severe spasticity. Relatively lower doses of HIFU can be used to reversibly block nerve function, to alleviate pain, to achieve an anesthetic effect, or to achieve a cosmetic effect. Where sensory nerves are not necessary for voluntary function, but are involved in pain associated with tumors or bone cancer, HIFU can be used to non-invasively destroy such sensory nerves to alleviate pain without drugs. Preferably, ultrasound imaging synchronized to the HIFU therapy is used to provide real-time ultrasound image guided HIFU therapy of neural structures.12-13-2012
20120165654MEANS AND METHOD FOR PERFORMING HYPERPOLARIZING GAS IMAGING - The present invention discloses a system for hyperpolarizing un-polarized gas within an animal. The system comprises hyper polarization means for hyperpolarizing the un-polarized gas, wherein the hyperpolarization of the un-polarized gas is provided in-situ within the analyzed animal.06-28-2012
20120165651DETECTOR ROTATION TYPE RADIATION THERAPY AND IMAGING HYBRID DEVICE - An imaging device, or a PET device, opposed gamma camera type PET device, or open PET device in particular, that is combined with a radiation therapy device, in which detectors are rotated to reduce incidence of nuclear fragments on the detectors. For example, in an opposed gamma camera type PET device, beam irradiation and detector rotation can be synchronized to prevent the detectors from interfering with the treatment beam and reduce the incidence of nuclear fragments on the detectors. This makes it possible to reduce the incidence of nuclear fragments on the detectors without interfering with a treatment beam, thereby enabling measurement of annihilation radiations and three-dimensional imaging of the irradiation field immediately after irradiation or during irradiation.06-28-2012
20120220857METHOD FOR MEASURING THE EMOTIONAL RESPONSE TO OLFACTIVE STIMULI - The invention relates to a method of identifying a fragrance sample using functional Magnetic Resonance Imaging to assess the ability of said fragrance sample to elicit a reward through the dopaminergic pathway; a fragrance sample identified by the method, and a method for preparing an accord or a fully formulated fragrance.08-30-2012
20120130227System and Method for Assessing Response to Chemotherapy Using Magnetic Resonance Elastography - A system and method for determining a response of a tumor following a chemotherapy process includes the use of a magnetic resonance elastography (MRE) driver and a magnetic resonance imaging (MRI) system. The method includes controlling the MRE driver and the MRI system to acquire raw MRE data from the tumor, inverting the raw MRE data to produce an elastogram of the tumor, and determining a response of the tumor to the chemotherapy process from the elastogram.05-24-2012
20120316424SURGICAL INSTRUMENTS FOR USE WITH DIAGNOSTIC SCANNING DEVICES - A surgical instrument for treating tissue during use of a diagnostic scanning device. The surgical instrument includes a housing, an actuating mechanism and an end effector assembly. The actuating mechanism is configured to activate the end effector assembly to treat tissue. At least a portion of the end effector is made of a material that is compatible with the diagnostic scanning device and allows a user to insert and activate the end effector to treat tissue at a surgical site within a patient while the surgical site is monitored during diagnostic scanning device.12-13-2012
20090270713NON-LINEAR SIGNAL SEPARATION METHOD USING NON-LINEAR STATE SPACE PROJECTION METHOD - There is provided a non-linear signal separation method using the non-linear state space projection method capable of separating an effective non-linear signal even if the S/N ratio is low by performing the time domain high speed non-linear state space projection when a signal is a multi-channel signal and has a periodicity. In the non-linear signal separation method using the non-linear state space projection method, an original signal having a complex signal which is a multi-channel and cyclic signal measured from one phenomenon is processed by using the time domain high-speed non-linear state space projection method so as to estimate a noise in the original signal and subtract the estimated noise from the original signal, thereby separating the signal to be measured in the original signal as a non-linear signal even when the S/N ratio is low.10-29-2009
20100204563SYSTEM AND METHOD FOR CORRECTING ATTENUATION IN HYBRID MEDICAL IMAGING - A hybrid medical imaging system comprises a nuclear medicine imaging subsystem for capturing an image of a target region of a subject, a magnetic resonance imaging (MRI) subsystem for capturing an MRI image of the target region based on at least one MRI parameter and processing structure communicating with the subsystems. The processing structure processes the MRI image to estimate attenuation within the target region and uses the estimated attenuation to correct the image captured by the nuclear medicine imaging subsystem.08-12-2010
20120136236IMAGING METHOD AND APPARATUS - A method of generating an image of a segment of a lumen structure comprises acquiring volumetric image data that comprises image data representative of a longitudinal segment of a lumen structure, extracting the segment of lumen structure from the volumetric image, calculating a thickness of planar MPR slab that at least encompasses the longitudinal segment of lumen structure, and rendering a planar MPR slab image based on the thickness and the volumetric image data.05-31-2012
20120136239SYSTEM FOR MAGNETIC RESONANCE AND X-RAY IMAGING - A patient table for a common imaging system including Magnetic Resonance and X-Ray retains the patient stationary in position prior to, during and subsequent to the imaging and includes a base, a patient support portion cantilevered from the base and a mattress. A safety system is provided for controlling the operation of the magnet and MR system and the X-Ray systems to allow effective safe operation and controls the movement of the magnet to the table and the movement of the X-Ray imaging systems to and from the table to locations where they do not interfere with the MR imaging.05-31-2012
20120136238HEMOGLOBIN CONTRAST IN MAGNETO-MOTIVE OPTICAL DOPPLER TOMOGRAPHY, OPTICAL COHERENCE TOMOGRAPHY, AND ULTRASOUND IMAGING METHODS AND APPARATUS - A novel contrast mechanism for imaging blood flow using magneto-motive optical Doppler tomography (MM-ODT), Optical Coherence Tomography, and Ultrasound. MM-ODT, OCT, and ultrasound combined with an externally applied temporally oscillating high-strength magnetic field detects erythrocytes moving according to the field gradient.05-31-2012
20120136237COMPACT, HYBRID AND INTEGRATED GAMMA/RF SYSTEM USED TO FORM SIMULTANEOUS PET OR SPECT AND MR IMAGES - The GAMMA/RF compact, hybrid and integrated system for PET-SPECT/MR simultaneous imaging of the invention comprises a GAMMA/RF device that integrates an RF coil, of the type used in conventional MR systems, with GAMMA radiation detector modules of the type used in PET or SPECT systems, so that combined PET or SPECT and MR images are obtained.05-31-2012
20100174173Implantable Medical Device Using Palladium - The present invention provides an improved implantable medical device comprising at least one portion made of a radiopaque material selected from the group consisting of various palladium alloys, including a palladium alloy having, by weight, rhenium in the range of up to about 20 percent, and preferably rhenium at about 14 percent of the alloy, by weight. The present invention further provides a wire guide, an embolization coil, a marker band, a stent, a filter, an RF ablation coil, and an electrode having at least one portion made of the radiopaque material.07-08-2010
20120253177Radiation Containing Seeds and Method for High Visibility Magnetic Imaging - A radioactive seed and method for making a radioactive seed with selective magnetic imaging characteristics are provided. The seed includes a housing which may include a metal shell for at least partially enclosing a radioactive material. The shell encloses a rod having a nickel layer with a phosphorous content, wherein the phosphorous content includes a level of phosphorous sufficient, when the seed is implanted in tissue, to provide a magnetic resonance image of the seed while substantially eliminating gross artifacts in the magnetic resonance image.10-04-2012
20120253176Systems and Methods for Debulking Visceral Fat - Systems and methods for debulking visceral fat within a subject, include: providing a focused ultrasound transducer configured to focus ultrasonic power at a focal spot; positioning the focused ultrasound transducer with respect to the subject so that the focused ultrasound transducer is enabled to transfer ultrasonic power into the subject; locating the focal spot of the focused ultrasound transducer with respect to at least one target region containing visceral fat within the subject; and debulking visceral fat within the target region by applying ultrasonic energy from the focused ultrasound transducer with sufficient power to cause the death of visceral fat tissue within the target region.10-04-2012
20120253175System and Method for Imbedded, High-Spatial Resolution, Fluoroscopic Tracking of Multi-Station, Contrast-Enhanced Magnetic Resonance Angiography - A method of producing a series of vasculature images over an extended field of view (FOV) larger than an FOV of an MRI system includes acquiring initial time-resolved image data from the vasculature and, during the acquiring process, reconstructing, in substantially real-time, a series of three-dimensional (3D) tracking images of the initial portion of the vasculature illustrating a current position of a contrast bolus in the vasculature as the contrast bolus passes through the initial portion of the vasculature. Based on a current position of the contrast bolus, the subject is moved to a subsequent imaging station to acquire subsequent time-resolved image data and reconstruct subsequent 3D tracking images of subsequent portions of the vasculature. This process is repeated and then an image is assembled that extends over the extended FOV using the initial time-resolved image data and the subsequent time-resolved image data.10-04-2012
20120253174IMAGE RECORDING DEVICE FOR THE SIMULTANEOUS RECORDING OF MAGNETIC RESONANCE IMAGE DATA AND NUCLEAR MEDICAL IMAGE DATA - An image recording device is disclosed for the simultaneous recording of magnetic resonance image data and nuclear medical image data, in particular PET image data. In at least one embodiment, the image recording device includes a nuclear medical detector arrangement integrated into a magnetic resonance device, wherein a fluorescence detector arrangement including an optical system and designed for fluorescence imaging is also integrated into the magnetic resonance device.10-04-2012
20120083686MR IMAGING GUIDED ULTRASOUND THERAPY - The invention relates to a therapeutic system which comprises: an ultrasound therapy unit (04-05-2012
20120172708MR IMAGING GUIDED THERAPHY - The invention relates to a therapeutic system which comprises an ultrasound therapy unit (07-05-2012
20120172710QUANTITATIVE ELASTOGRAPHY - A contact force sensor is used to detect an instantaneous contact force for an ultrasound probe while an ultrasound image is obtained. The contact force can be used to evaluate tissue deformation in response to the applied force, which permits enhanced imaging such as estimation of undeformed tissue shapes and a determination of tissue elasticity.07-05-2012
20120172711Injectable Vascular Access Port with Discernable Markers for Identification - An improved injection port identification for injection ports implanted under the skin of a patient. The injection port has an x-ray discernable marker allowing for the determination of a pressure rating for the injection port when so implanted. A plurality of concurrent visual, RF, light emitting and sonic means for signaling the port's pressure rating are also employable to provide multiple concurrent affirmations of the port's readiness for high pressure injections.07-05-2012
20120215093SYSTEM AND METHOD FOR PROVIDING PATIENT REGISTRATION WITHOUT FIDUCIALS - A method for providing patient registration without fiducials comprises the steps of: spatially placing an ultrasound image of a patient randomly at different starting positions relative to a preoperative image; creating an independent registration corresponding to each different starting positions, by optimizing a spatial transformation between the preoperative image and the ultrasound image to provide a first batch of registrations; executing a second registration to fine-tune the alignment between the preoperative image and the ultrasound image; and concatenating the spatial transformation to obtain spatial transformation between the patient in an operating room and a corresponding preoperative image.08-23-2012
20120316427TIMING TECHNIQUES FOR MAGNETIC RESONANCE IMAGING - The disclosure is directed to techniques in which magnetic resonance imaging (MRI) is coordinated with the operation of an implantable medical device (IMD). By using an IMD to sense conditions, MRI can be improved because the sensed conditions can accurately define timing for application of electromagnetic radiation bursts. Moreover, by applying stimulation pulses specifically to coordinate the electromagnetic radiation bursts, the MRI may also be improved.12-13-2012
20120316425TIMING OF A PLURALITY OF IMAGING OBSERVATION ELEMENTS BASED ON A VOLUME OF INTEREST - Systems and methods are provided for timing of a plurality of imaging observation elements based on a volume of interest (VOI). One system includes a first imaging element configured to generate a first observation of a first object, wherein the first observation is generated at a first time, and the first object is associated with a volume of interest (VOI). A second imaging element is configured to generate a first observation of a second object, the first observation of the second object generated at a second time, wherein the second object is associated with the VOI. The system is configured to determine a first positioning of the VOI based on the first observation of the first object and the first observation of the second object, determine a plurality of imaging times for the first imaging element to generate a plurality of additional observations of the first object.12-13-2012
20100049030MRI GUIDED RADIATION THERAPY - Radiation therapy of a lesion within a patient is guided to take into account movement of the lesion caused by respiration and/or cardiac effects by using MRI to image the patient while on the treatment support to obtain a series of images of a location of the lesion within the patient while obtaining data relating to respiration and/or cardiac function of the patient to generate lesion movement data as a function of respiration and/or cardiac function. After the magnet is removed from the bunker, during the radiation therapy, real time data relating to respiration and/or cardiac function of the patient is used to guide the radiation therapy using the lesion movement data obtained during the imaging.02-25-2010
20120179026Method for Registering a Physical Space to Image Space - A method and apparatus for registering physical space to image space is disclosed. The system allows for determining fiducial markers as pixels or voxels in image data. The system can correlate and register the determined fiducial points with fiducial markers in physical space.07-12-2012
20120179025CT AND MRI SYNCHRONOUS DETECTION POSITIONING NEEDLE - Disclosed is a CT and MRI synchronous detection positioning needle. The needle comprises a silicone tube which is internally provided with a guide needle; the two sides of the guide needle are provided with hollow cavities; each hollow cavity is internally provided with membranes dividing the hollow cavity into a plurality of small chambers which are filled with liquid, wherein a CT contrast agent is filled in a plurality of small chambers at one side of the guide needle, and an MRI contrast agent is filled in a plurality of small chambers at the other side of the guide needle. In the invention, specially designed silicone positioning needles are implanted in vivo, and synchronous comparison of different image data and pathological data is implemented by means of multi-plane reconstruction technology, so the CT and MRI synchronous detection positioning needle can be widely applied to experimental study on tumors.07-12-2012
20100022868ACTIVE MRI COMPATIBLE AND VISIBLE iMRI CATHETER - A catheter for use with magnetic resonance imaging including a catheter body, a radio frequency antenna disposed in a distal end of the catheter body, a first ultrasonic transducer disposed in the distal end of the catheter body and being electrically connected to the radio frequency antenna, an acoustic waveguide disposed in the catheter body and extending from the distal end to a proximal end of the catheter body, the acoustic waveguide being acoustically matched to the first ultrasonic transducer. The catheter also has a second ultrasonic transducer disposed in the proximal end of the catheter body.01-28-2010
20090088625 Photonic Based Non-Invasive Surgery System That Includes Automated Cell Control and Eradication Via Pre-Calculated Feed-Forward Control Plus Image Feedback Control For Targeted Energy Delivery - A photonic based non-invasive surgery system that includes an imaging device such as an MRI device and at least two beam generators for generating beams of energy for delivery to a target in the person's body, where the beams of energy intersect at a point. The system also includes a feed-forward control for precalculating anticipated deflections and resulting pathways as the beams of energy travel throughout the person's body, and a feedback control to obtain and use information gathered by the imaging device.04-02-2009
20120253172Radiation therapy system with high frequency shielding - A radiation therapy system is proposed. The system has a magnetic resonance imaging device with a first and second magnetic coil units distanced from one another by a gap. The coil units interact to generate a magnetic field propagating along a longitudinal axis. The system has a linear accelerator arranged at a radial distance from the longitudinal axis in the gap or in the radial extension of the gap. The system also has a high frequency shielding arrangement with a first and second high frequency shielding cabins arranged adjacent to the first and second magnetic coil units respectively and high frequency sealed connected to one another with a tubular high frequency shielding unit arranged along the longitudinal axis within the first and second magnetic coil units. A high frequency shielding concept is independent of an embodiment of the magnetic system of the imaging device and is universally applicable.10-04-2012
20120253171INFORMATION PROCESSING APPARATUS, IMAGING SYSTEM, INFORMATION PROCESSING METHOD, AND PROGRAM CAUSING COMPUTER TO EXECUTE INFORMATION PROCESSING - An information processing apparatus includes a first acquisition unit configured to acquire a plurality of positions, in a three-dimensional image of a subject, obtained based on a sternum of the subject, a second acquisition unit configured to acquire a plurality of positions, in the subject, obtained based on the sternum of the subject, and a calculation unit configured to calculate a correspondence relationship in position between the subject and the three-dimensional image based on the plurality of positions acquired by the first acquisition unit and the plurality of positions acquired by the second acquisition unit.10-04-2012
20120190965MR Compatible Stereoscopic Viewing Device for use in the Bore of an MR Magnet - In an MR guided surgical system which is carried out in the bore of an MR magnet, there is provided a microscope system for viewing the required part of a patient which includes stereoscopic viewing components arranged for use in generating 2D and 3D images displayed to the surgeon. The optical assembly is adjustable to change the view and the visual images are overlaid by the MR images. The visual image can be adjusted in response to movement of the surgical tool and the MR image displayed and/or the image obtained can be modified in response to change in the visual image and/or movement of the tool. The components in the bore are made compatible with the MR environment.07-26-2012
20120259201System and Method for Inertial Magnetic Resonance Elastography Driver for Use With Interventional Medical Device - A system and method for performing a magnetic resonance elastography (MRE) procedure using an MRI system to monitor operation of a medical device performing a medical procedure. The driver system includes a housing, a port located in the housing and connected to a driving power, and an inertial driver moved within the housing by the driving power. A passage is formed in the housing and extends from a first opening in the housing, through the inertial driver, and to a second opening in the housing. The inertial driver receives a medical device extending through the passage and engages the medical device to impart oscillatory motion thereto as the inertial driver is moved by the driving power. The imparted oscillatory motion travels along the medical device as a waveguide to deliver the oscillatory motion to tissue receiving the medical procedure to perform the MRE procedure.10-11-2012
20100191096PARAMAGNETIC BIOMOLECULE COMPLEXES AND USES THEREOF IN THE ASSESSMENT OF ORGAN FUNCTION - The present invention relates to complexes comprising one or more marker(s) and one or more biomolecules. The complexes according to the present invention have a variety of utilities, such as utility as a contrast agent in imaging methods, for example magnetic resonance imaging.07-29-2010
20120265050Omni-Tomographic Imaging for Interior Reconstruction using Simultaneous Data Acquisition from Multiple Imaging Modalities - Embodiments of the invention relate to omni-tomographic imaging or grand fusion imaging, i.e., large scale fusion of simultaneous data acquisition from multiple imaging modalities such as CT, MRI, PET, SPECT, US, and optical imaging. A preferred omni-tomography system of the invention comprises two or more imaging modalities operably configured for concurrent signal acquisition for performing ROI-targeted reconstruction and contained in a single gantry with a first inner ring as a permanent magnet; a second middle ring containing an x-ray tube, detector array, and a pair of SPECT detectors; and a third outer ring for containing PET crystals and electronics. Omni-tomography offers great synergy in vivo for diagnosis, intervention, and drug development, and can be made versatile and cost-effective, and as such is expected to become an unprecedented imaging platform for development of systems biology and modern medicine.10-18-2012
20120265051APPARATUS AND METHODS FOR MRI-COMPATIBLE HAPTIC INTERFACE - In one embodiment, the system of these teachings includes a master robot/haptic device providing haptic feedback to and receiving position commands from an operator, a robot controller receiving position information and providing force information to the master robot/haptic device, a navigation component receiving images from an MRI scanner, the navigation component providing trajectory planning information to the robot controller, a slave robot driving a needle, the slave robot receiving control information from the robot MRI controller, and a fiberoptic sensor operatively connected to the slave robot; the fiberoptic sensor providing data to the robot controller; the data being utilized by the robot controller to provide force information to the master robot/haptic device. In one instance, the present teachings include a fiberoptic force sensor and an apparatus for integrating the fiberoptic sensor into a teleoperated MRI-compatible surgical system. Methods for use are disclosed.10-18-2012
20120323111METHOD AND SYSTEM FOR CHARACTERIZING AND VISUALIZING ELECTROMAGNETIC TRACKING ERRORS - A calibration/surgical tool (12-20-2012
20120271151Method for Determining Locations of Implanted Electrodes with Medical Images - A method for accurate localization and visualization of implanted electrodes, such as implanted intracranial electrodes, is provided. More particularly, a realistic representation of intracranial electrode positions on patient-specific post-implantation MRI brain renderings is obtained. The resulting computer models provide an accurate depiction of electrode locations on three-dimensional brain renderings that are suitable for use in surgical planning of resection boundaries around, for example, epileptic zones. Electrodes placed inter-hemispherically are also visible with this method. In addition, a method for creating electrode “shadows” cast upon the brain model surface is provided. These electrode shadows are useful for estimating cortical areas sampled by iEEG and for locating electrodes that may straddle sulci and contact two adjacent cortical gyri.10-25-2012
20120271150Flexible Passive Acoustic Driver for Magnetic Resonance Elastography - A flexible passive acoustic driver for use in an acoustic driver system which applies an oscillating stress to a subject undergoing a magnetic resonance elastography (MRE) examination which includes receiving acoustic pressure waves from an active driver through a tube and imparts pressure waves to a subject of an imaging procedure. In one configuration, the passive driver includes a flexible bag that forms the walls of an acoustic cavity, and a structure filling material located inside the acoustic cavity provides support for the flexible bag. The flexible bag conforms to the shape of the subject and may be held in place by an elastic band. The passive driver can have an integrated or detachable non-active push-on compartment which is rigid or semi-flexible to improve the human-driver mechanical coupling and the driver energy efficiency of converting acoustic pressure to mechanical vibration applied to a subject.10-25-2012
20100228116SYSTEM AND METHOD OF OPTIMIZING A HETEROGENEOUS RADIATION DOSE TO BE DELIVERED TO A PATIENT - A radiation therapy treatment system and method of optimizing a heterogeneous dose to be delivered to a patient. The system includes a computer processor and a software program stored in a computer readable medium accessible by the computer processor. The software program is operable to receive a prescribed heterogeneous radiation dose to be delivered to the patient, determine a homogeneous reference dose, calculate a complementary radiation dose by determining a difference between the homogeneous reference dose and the heterogeneous radiation dose, generate a treatment plan for the patient, the treatment plan including an optimized radiation dose to be delivered to the patient, combine the complementary radiation dose and the optimized radiation dose, evaluate the combined radiation dose with respect to the homogeneous reference dose, and display the combined radiation dose.09-09-2010
20110237930MRI compatible motor and positioning system - A thermal therapy system is provided. The system includes an applicator and a device for supporting and moving the applicator within a patient's body during therapy. Some embodiments include an elongated ultrasound energy applicator that is positioned using a plurality of positioners along a corresponding plurality of axes. Also, a rotational driver or motor is provided to rotate the thermal therapy applicator in the patient's body during treatment. The apparatus is constructed of magnetically-compatible materials and has a design to avoid or minimize interference between the drive components of the apparatus and a MRI imaging system in use during the treatment.09-29-2011
20120089009METHODS AND APPARATUS TO DELIVER NANOPARTICLES TO TISSUE USINGELECTRONANOTHERAPY - Methods, systems, and apparatus are disclosed to provide delivery of nanoparticles to tissue using electro-nanotherapy or nanoablation.04-12-2012
20120089008SYSTEM AND METHOD FOR PASSIVE MEDICAL DEVICE NAVIGATION UNDER REAL-TIME MRI GUIDANCE - A method for tracking a needle along a path under real-time magnetic resonance imaging (MRI) guidance includes extracting a candidate needle artifact region from a plurality of incoming MR images of a needle inside biological tissue, determining an initial needle direction vector from the candidate needle artifact region in each of the plurality of incoming needle images, determining an initial needle base point from an intersection of the needle direction vector with a first incoming needle image, and an initial needle tip point from an intersection of the needle direction vector with a last incoming needle image, and tracking said needle by minimizing a cost function of the initial base point and initial direction vector to calculate an updated base point and updated direction vector. The updated base point and direction vector are used to visualize the advance of the needle along the path through the biological tissue.04-12-2012
20120089007Dual Imaging Acquisition Using Common Time-Base Frequency - Timing in a medical imaging system. The system comprises a magnetic resonance imaging (MRI) subsystem and a non-MRI subsystem. Operation of the non-MRI subsystem involves a timing signal within a radio frequency (RF) cabin of the MRI subsystem. Basing each non-MRI subsystem timing signal on a time base common between the MRI subsystem and the non-MRI subsystem. The non-MRI subsystem can be a medical imaging subsystem. The non-MRI medical imaging subsystem can be a positron emission tomography (PET) subsystem. Each non-MRI subsystem timing signal that based on the common time base can be created using the same model of equipment used for creating timing signals in the MRI subsystem. At least one stage of the non-MRI subsystem timing signal based on the common time base can be created using the same equipment used for creating timing signals in the MRI subsystem.04-12-2012
20120330130ASSEMBLY TO PERFORM IMAGING ON RODENTS - An imaging device for imaging an anaesthetized animal such as a rodent (rats or mice or other animals), with the device having a split array coil capable of providing at least two channels for use in a restraining assembly with animal bed for magnetic resonance imaging (MRI) the animal in real-time in a non-destructive manner.12-27-2012
20120330128PET-MRI CONVERGENCE SYSTEM - A Positron Emission Tomography (PET)-Magnetic Resonance Imaging (MRI) convergence system may be provided that includes: a magnet bore having a cylindrical shape, an outer wall and an inner wall; a gradient coil disposed to contact with the inner wall of the magnet bore; a body coil which is disposed to contact with the inner wall of the gradient coil, emits an RF pulse signal, and has a first through-hole formed therein; and an MRI RF receiving coil detecting MRI data corresponding to the RF pulse signal. The PET detector includes a second through-hole formed therein and contacts with one end of the body coil such that the first through-hole is connected to the second through-hole. The examinee transporter is transportable through the first through-hole and the second through-hole.12-27-2012
20120330129MEDICAL VISUALIZATION SYSTEMS AND RELATED METHODS OF USE - Embodiments of the disclosure relate to medical devices and, in particular, to medical visualization systems and methods of use. In one embodiment, a medical visualization system may include a video source configured for insertion into a patient and an external data source. A central processing unit in communication with the video source and the external data source may be configured to merge data from the video source and data from the external data source into a left hybrid image and a right hybrid image. The medical visualization system may further include eyewear having left and right oculars in communication with the central processing unit. The left ocular and right ocular may each include a display, and the displays may be configured to project the left hybrid image on the left display and the right hybrid image on the right display.12-27-2012
20120330131MR COMPATIBLE COMPRESSION BASED NUCLEAR IMAGING SYSTEM FOR BREAST CANCER - An apparatus combines magnetic resonance (MR) and nuclear imaging of human breast for cancer diagnosis. An MRI system including an MR breast RF coil is combined with a nuclear imaging system having a detector disposed or disposable within the MR breast RF coil arranged and configured for the performance of simultaneous or sequential coregistered breast MRI and nuclear imaging. A selectively controlled compression mechanism for lightly compresses the breast being imaged. The remotely controlled compression mechanism is integrated with the MR breast RF coil.12-27-2012
20110306869APPARATUS AND METHOD FOR PRODUCING TOMOGRAPHIC IMAGE - An apparatus and method for producing tomographic image is disclosed. The disclosed apparatus for producing tomographic image comprises: an ultrasonic imaging unit configured to obtain multiple ultrasonic images of a subject; a tomographic imaging unit configured to obtain one or more tomographic image data of the subject; and a tomographic image correction unit configured to produce corrected tomographic image of a tomographic image which can be produced from the one or more tomographic image data by using the multiple ultrasonic images.12-15-2011
20110319747MAGNETIC RESONANCE DEVICE FOR USE IN A MAGNETIC RESONANCE-GUIDED ULTRASOUND TREATMENT - A magnetic resonance device for use in a magnetic resonance-guided ultrasound treatment has a magnet housing defining a patient receptacle and including a primary magnet, and an ultrasound device, such as an HIFU device, with a transducer unit, The magnet housing has a receptacle therein for the transducer unit of the ultrasound device, in particular in the region of the homogeneity volume.12-29-2011
20120101366MAGNETIC STIMULATION DEVICE AND METHOD - The present publication discloses a device and method for generating magnetic pulses and directing them to brain. The device in accordance with the invention comprises means (04-26-2012
20120101365ASSESSMENT OF BLOOD-BRAIN BARRIER DISRUPTION - A method of analyzing a blood-brain bather of a subject is disclosed. A detectable dose of an MRI contrast agent is administered to the subject, and a plurality of magnetic resonance images of the subject's brain are acquired over a predetermined time-period. Two or more of the magnetic resonance images are compared thereamongst so as to determine variations in concentration of the contrast agent in the brain, and blood-brain barrier function is assessed based on the variations.04-26-2012
20120101364SYSTEM AND METHOD FOR MAGNETIC-RESONANCE-GUIDED ELECTROPHYSIOLOGIC AND ABLATION PROCEDURES - A system and method for using magnetic resonance imaging to increase the accuracy of electrophysiologic procedures includes an invasive combined electrophysiology and imaging antenna catheter which includes an RF antenna for receiving magnetic resonance signals and diagnostic electrodes for receiving electrical potentials. The combined electrophysiology and imaging antenna catheter is used in combination with a magnetic resonance imaging scanner to guide and provide visualization during electrophysiologic diagnostic or therapeutic procedures, such as ablation of cardiac arrhythmias. The combined electrophysiology and imaging antenna catheter may further include an ablation tip, and be used as an intracardiac device to deliver energy to selected areas of tissue and visualize the resulting ablation lesions.04-26-2012
20120101363METHODS AND APPARATUS FOR PATIENT TREATMENT USING MAGNETIC MEDICAL HARDWARE - Methods, systems, and apparatus are disclosed to provide treatment to patient tissue using medical hardware incorporating magnetic material. Methods, systems, and apparatus are disclosed to provide magnetic induction heating of cells at a tissue site in a patient.04-26-2012
20120101362CATHETER BEING USABLE IN A MAGNETIC RESONANCE IMAGING SYSTEM - The present invention relates to a catheter (04-26-2012
20120289815METHODS AND DEVICES FOR DIAGNOSING, MONITORING, OR TREATING MEDICAL CONDITIONS THROUGH AN OPENING THROUGH AN AIRWAY WALL - Methods and devices for diagnosing, monitoring, and/or treating tissue through an opening or port through an airway wall are provided herein.11-15-2012
20100179415MODEL-BASED DIFFERENTIAL DIAGNOSIS OF DEMENTIA AND INTERACTIVE SETTING OF LEVEL OF SIGNIFICANCE - When detecting and classifying hypo-metabolic regions in the brain to facilitate dementia diagnosis, a patient's brain scan image, generated using an FDG-PET scan, is compared to a plurality of hypo-metabolic region patterns in brain scan images associated with a plurality of types of dementia. In a fully automated mode, the patient's scan is compared to all scans stored in a knowledge base, and a type of dementia associated with a most likely match is output to a user along with a highlighted image of the patient' s brain. In a semi-automated mode, a user specifies two or more types of dementia, and the patient's scan is compared to scans typical of the specified types. Diagnosis information including respective likelihoods for each type is then output to the user. Additionally, the user can adjust a threshold significance level to increase or decrease a number of voxels that are included in hypo-metabolic regions highlighted in the patient' brain scan image.07-15-2010
20100179414IMAGE GUIDED THERAPY - A therapeutic system comprises a therapy module to direct a therapeutic action, e.g. focused ultrasound or RF energy to a target. An imaging module such as an magnetic resonance examination system generates image information of a therapy region that includes the target. By way of a motion analysis module a motion vector field is derived from the image information of the therapy region. A control module controls the therapy module on the basis of the motion vector field. Notably, on the basis of the motion vector field an accurate temperature distribution is derived from magnetic resonance signals and the motion vector field. Also magnetic resonance elastography data may be employed to improve the accuracy of the temperature distribution.07-15-2010
20100179413DETERMINATION AND DISPLAY OF MATERIAL PROPERTIES - The invention provides for the visualisation of conventional and parametric images of materials as they are progressively distorted during examination. A conventional image is displayed simultaneously alongside one or more parametric images derived from the original image data, with the parametric images displaying mechanical properties such as elasticity and mobility. The mobility values are calculated from the tracking error obtained from a motion or strain estimation algorithm applied to a sequence of image frames. The values of elasticity and mobility are displayed in a colour overlay on the conventional image background and the transparency of the overlay is varied according to the parameter values to de-emphasise less relevant values.07-15-2010
20130012805COMPUTER AIDED DIAGNOSTIC METHOD AND DEVICE - A method for generating a map of a region of a patient's body containing one or more lesions that provides information about MR diffusion properties and/or level of suspicion of malignancy. Performing at least one first scan of the region with an MRI apparatus set to a first b value to obtain a first matrix of pixel or voxel values, int(B01-10-2013
20130012804METHODS FOR PHYSIOLOGICAL MONITORING, TRAINING, EXERCISE AND REGULATION - A computer assisted method for measuring activity of one or more internal voxels of a brain using computer executable logic that receives and utilizes the measured brain activity. The computer assisted methods can relate to physiological monitoring, training, exercise and regulation.01-10-2013
20120150018SHIELD TYPE RADIATION THERAPY AND IMAGING HYBRID DEVICE - A shielding structure against nuclear fragments (referred to as a shield) is operated according to ON and OFF of beam irradiation so as to reduce incidence of nuclear fragments on detectors during beam irradiation. This enables measurement of annihilation radiations and three-dimensional imaging of the irradiation field immediately after irradiation or even during irradiation.06-14-2012
20110160567FUNCTIONAL MRI CARDIAC OPTIMIZATION - An implantable or other ambulatory device, such as a pacer, defibrillator, or other cardiac function management device, can use imaging information, such as one or more of cardiac functional magnetic resonance imaging (fMRI) information or cardiac magnetic resonance imaging (MRI) information, such as for helping optimize one or more parameters of the implantable or other ambulatory device.06-30-2011
20110160566MRI AND ULTRASOUND GUIDED TREATMENT ON A PATIENT - A method is provided for guiding a procedure on a region of interest in a body part of patient, where the body part moves within the patient by breathing, cardiac or other action. The procedure includes radiation therapy, or guidance of a probe for example for biopsy or brachytherapy. The method includes using an MRI system to obtain an MR image of the body part, during the procedure on the body part of the patient, obtaining real time ultrasound images of the body part of the patient as the body part moves within the body of the patient, registering the MR image of the body part with the ultrasound image of the body part so as to locate the region of interest in the ultrasound image of the body part and using the registered images to target the action to the region of interest as the body part moves.06-30-2011
20110160565DETECTING PROXIMITY TO MRI SCANNER - A plurality of separate indications of a scanner field can be received using a corresponding plurality of scanner field sensors of an implantable medical device (IMD). In an example, the IMD can be switched from a first therapy mode to a second therapy mode using one or more of the plurality of scanner field sensors, and from the second therapy mode back to the first therapy mode using each of the plurality of scanner field sensors. In certain examples, shock therapy can be terminated or inhibited using a detected proximity of the IMD to a magnetic resonance imaging (MRI) scanner, or antitachycardia pacing (ATP) can be terminated or inhibited using a detected active scan of the MRI scanner.06-30-2011
20090043189Mobile combined MRI/PET apparatus - A combined positron emission tomography/magnetic resonance imaging apparatus, in a trailer housing is disclosed, for imaging organs of an examination object in an examination space. In at least one embodiment, the positron emission tomography/magnetic resonance imaging apparatus includes a positron emission tomography apparatus with at least one radiation detector and a magnetic resonance imaging apparatus with at least one main magnetic field coil for generating a main magnetic field, at least one gradient coil for generating a magnetic gradient field, and a radio-frequency antenna device for transmitting excitation pulses and receiving magnetic resonance signals from the examination space, the radiation detector and the at least one gradient coil being arranged coaxially and at substantially the same axial height. In order to create a mobile MRI/PET apparatus which is designed as compactly as possible and, firstly, satisfies the radiation protection requirements for protecting the surroundings of the measurement apparatus to the best possible extent and, secondly, excludes interfering environmental influences on the measurement apparatus, a shielding arrangement with at least one shielding element for attenuating the main magnetic field and the gradient field and also the annihilation radiation outside the trailer housing is provided in at least one embodiment.02-12-2009
20080228063System and method for irradiating a target with electromagnetic radiation to produce a heated region - A system and corresponding method for irradiating a target with electromagnetic radiation to produce a heated region. The system comprises a coupling device operable to couple electromagnetic radiation from a magnetic resonance imaging system. A plurality of energy radiator applicators are connected to the coupling device to receive electromagnetic radiation energy from the coupling device. Each of the radiator applicators is operable to emit a radio frequency heating signal using the electromagnetic radiation energy from the coupling device. A bolus filled with a dielectric fluid is positioned within the inner area of the MRI system. The bolus is operable to receive the radio frequency heating signals from the plurality of energy radiator applicators and direct the radio frequency heating signals into a section of the body to produce a heated region within the body.09-18-2008
20110263965PET DETECTOR MODULE USING GAPD COMPOSED OF LARGE AREA MICRO-CELLS - Provided is a positron emission tomography (PET) detector module using Geiger-mode avalanche photodiode (GAPD) as a photosensor. The PET detector module includes: a PET detector unit comprising a scintillation crystal detecting gamma rays emitted from a living body and converting them into a flash of light and a first GAPD photosensor and a second GAPD photosensor each being connected to either end of the scintillation crystal and converting the light flash into an electrical signal; and a reaction depth determination unit receiving the signals from the PET detector unit and comparing amplitude of the signals detected by the first GAPD photosensor and the second GAPD photosensor, thereby determining the position where the gamma rays are incident on the scintillation crystal (reaction depth). The disclosed PET detector module can provide high energy and high energy and reaction depth data while maintaining linearity.10-27-2011
20080221430APPARATUS FOR MAGNETIC RESONANCE IMAGING - A magnetic resonance imaging (MRI) apparatus for high-speed and high-accuracy detection of cell positions labeled with magnetic nanoparticles. A transmitter coil is controlled to generate amplitude-modulated burst RF pulses as excitation RF pulses whose amplitude is modulated by a function that repeatedly inverts the polarity of multiple high-frequency magnetic field sub-pulses separated time-wise and changes the amplitude at each polarity inversion, moreover the time interval of the amplitude-modulated burst RF pulse is set to effectively 1/(2×a first frequency), and the transmitter coil controlled so the carrier frequency of the amplitude-modulated burst RF pulse is set to a second frequency shifted substantially from the first frequency of the magnetic resonance frequency of the proton at the magnetic field strength in the MRI apparatus. The first frequency is here determined based on magnetic nanoparticle information loaded from the magnetic nanoparticle information storage unit and the magnetic resonance frequency of the proton in the static magnetic field. The MRI apparatus can in this way detect the position of cells labeled with magnetic nanoparticles, with high-speed and high accuracy.09-11-2008
20120253173IMAGE PROCESSING APPARATUS, ULTRASONIC PHOTOGRAPHING SYSTEM, IMAGE PROCESSING METHOD THEREFOR, AND STORAGE MEDIUM STORING PROGRAM - An image processing apparatus includes an ultrasonic image obtaining unit configured to obtain an ultrasonic image by capturing a subject by ultrasound, a generation unit configured to generate a corresponding cross-sectional surface which corresponds to an image capturing cross-sectional surface of the ultrasonic image, which is parallel to a reference direction, and which includes a position specified in advance from a three-dimensional image of the subject, and a cross-sectional image obtaining unit configured to obtain a cross-sectional image of the three-dimensional image from the generated corresponding cross-sectional surface.10-04-2012
20080214927Integrated Pet-Mri Scanner - One embodiment of the present invention provides an integrated PET-MRI scanner. This integrated scanner includes a main magnet that generates a magnetic field, wherein images of the subject is generated in a central region of the magnetic field. It also includes a PET scanner which is enclosed by the main magnet. The PET scanner further comprises: (1) at least one ring of scintillators, which is situated in the central region of the magnetic field and, (2) one or more photodetectors, which are coupled to the ring of scintillators, so that the one or more photodetectors are outside the central region of the magnetic field. The integrated scanner also includes radio-frequency (RF) coils which are enclosed by the PET scanner. By keeping the photodetectors and associated circuitry outside the central region of the magnetic field, the integrated scanner reduces the electromagnetic interference (EMI) between the PET scanner and the MRI scanner.09-04-2008
20130172728ATHEROSCLEROSIS THERAPY VIA DELIVERY AND LOCALIZED HEATING OF MICRO SIZE PARTICLES - The present invention relates generally to the treatment of atherosclerosis and thrombosis. Specifically, the invention relates to a method for removing vascular deposits by locally heating plaque sites with micron size particles that are administered intravenously and are heated inductively.07-04-2013
20130172729ACTIVE ADAPTIVE DETUNING SYSTEMS AND METHODS FOR INTERVENTIONAL DEVICES - Active MRI compatible interventional devices, such as catheters, include at least one RF antenna so that they are visible under MRI analysis. However, metallic structures within intravascular devices may heat up significantly during interventional MRI procedures due to eddy current formation over the conductive transmission lines. The electrical field coupling that occurs between interventional devices and RF signals depend on the position and orientation of interventional device within the bore and the insertion length of the interventional device. The system detects an induced current signal during RF transmission phase and selectively adjusts the impedance value associated with the interventional device by using a varactor and integrated circuit components in such a manner that the currents induced in the interventional device are below a threshold current level, thereby controlling current levels and heating in the interventional device.07-04-2013
20130137963SYSTEM AND METHOD FOR AUTOMATICALLY INITIALIZING OR INITIATING A MOTION COMPENSATION ALGORITHM - A system and method for automatically initializing or initiating a motion compensation algorithm is provided. The system includes a processing apparatus configured to acquire data representing information relating to movement of a medical device, determine whether the medical device is stationary based on the information represented by said data, and automatically initiate the execution of the motion compensation algorithm in response to a determination that the medical device is stationary. In an exemplary embodiment, the system further comprises the medical device. The method comprises acquiring data representing information relating to movement of a medical device. The method further comprises determining whether the medical device is stationary based on the information represented by the acquired data. The method still further comprises automatically initiating the execution of the algorithm in response to a determination that the medical device is stationary.05-30-2013
20130096416METHOD AND APPARATUS FOR MEASURING A RATIO OF A VARIABLE IN MEDICAL IMAGING DATA - In a method and apparatus for measuring a ratio of a variable for assessment in medical imaging data of a subject, a viewable image is generated from source imaging data of the subject. A pair of regions of interest for arrangement on the viewable image is then generated, and a value of the variable for each region of the pair from the source imaging data is determined. The ratio of the two values is then determined from the pair.04-18-2013
20130102878Trackable Biopsy Needle - A trackable biopsy needle assembly including an inner tube of an outer cannula, an inner dielectric layer, a first coil, a second coil, a third coil, an outer dielectric layer, and an outer tube of the outer cannula. The inner tube defines a bore. The inner dielectric layer is secured onto an outer surface of the inner tube. The first, second, and third coils are wound over the inner dielectric layer. The outer dielectric layer is secured onto the first coil, the second coil, and the third coil. The outer tube is fastened to the outer dielectric layer.04-25-2013
20130102879Method For Correcting Susceptibility-Induced Image Artifacts In MRI After Prospective Motion Correction - A method of magnetic resonance imaging (MRI) is characterized by the following steps: a) forming a susceptibility model (04-25-2013
20130131494METHOD AND SYSTEM FOR GUIDED SHIELDING OF A PATIENT VOLUME FROM ULTRASOUND ENERGY - In order to decrease collateral heating of ribs and tissue surrounding the ribs in a patient during high-intensity focused ultrasound (HIFU) therapy, shielding material may be positioned on or adjacent to an external surface of the patient and aligned with ribs to be protected using a magnetic resonance imaging (MRI) system. The MRI system may be used to image the shielding material and the ribs to be protected, and an error of alignment between the ribs to be protected and the shielding material may be determined based on the images. The shielding or masking material may be repositioned based on the determined error of alignment, images of the shielding material and the ribs to be protected may be reacquired, and the error of alignment may be redetermined based on the reacquired images until the shielding material is aligned with the ribs to be protected.05-23-2013
20130131495PLANNING SYSTEM FOR TARGETING TISSUE STRUCTURES WITH ULTRASOUND - The disclosed subject matter provides systems and methods for targeting tissue structures and applying ultrasound thereto. A method according to the disclosed subject matter for targeting a tissue structure using corresponding tissue structure image data includes inputting the tissue structure image data into a targeting simulator, determining acoustic properties of the tissue structure from the corresponding tissue structure image data, and utilizing the determined acoustic properties to align a simulated transducer with the tissue structure such that the tissue structure is targeted. The method can further include acquiring the tissue structure image data, aligning the image data with an atlas of a body structure encompassing the tissue structure and/or selecting parameters of the simulated transducer such that a focal region of an ultrasound wave generated by the simulated transducer targets the tissue structure.05-23-2013
20130131496MRI-GUIDED CATHETERS - An MRI-compatible catheter that reduces localized heating due to MR scanner-induced currents includes an elongated flexible shaft having a distal end portion and an opposite proximal end portion. A handle is attached to the proximal end portion and includes an electrical connector interface configured to be in electrical communication with an MRI scanner. One or more RF tracking coils are positioned adjacent the distal end portion of the shaft. Each RF tracking coil includes a conductive lead, such as a coaxial cable, that extends between the RF tracking coil and the electrical connector interface and electrically connects the RF tracking coil to an MRI scanner. In some embodiments of the present invention, the conductive lead has a length sufficient to define an odd harmonic/multiple of a quarter wavelength of the operational frequency of the MRI Scanner, and/or includes a series of pre-formed back and forth segments along its length.05-23-2013
20110218420RADIATION THERAPY SYSTEM - A radiation therapy System comprises a magnetic resonance imaging (MRI) apparatus and a linear accelerator capable of generating a beam of radiation. The linear accelerator is immersed in and oriented with respect to the MRI magnetic field to expose the linear accelerator to magnetic force that directs particles therein along a central axis thereof.09-08-2011
20080200797METHOD AND APPARATUS FOR ENDOBRONCHIAL DIAGNOSIS - The present invention provides systems, methods, devices and kits for assessing the level of pulmonary disease in individual lung compartments. A lung compartment comprises a subportion of a lung, such as a lobe, a segment or a subsegment, for example. By measuring individual lung compartments, the level of disease of the pulmonary system may be more precisely defined by determining values of disease parameters reflective of individual subportions or compartments of a lung. Likewise, compartments may be separately imaged to provide further measurement information. Once individual compartments are characterized, they may be compared and ranked based on a number of variables reflecting, for example, level of disease or need for treatment. Such comparison may be aided by simultaneous display of such variables or images on a visual display. Further, the same tests may be performed on the lung as a whole or on both lungs and to determine the affect of the diseased lung compartments on the overall lung performance. In addition, the diseased lung compartments may be temporarily isolated and the measurement tests performed to determine the affect of the isolation on overall lung performance. As a result, the most beneficial treatment options may be selected.08-21-2008
20080200796Method and system for computerized drawing and writing during functional magnetic resonance imaging - The present invention provides a method and device to record and visualize drawing and writing movements during functional magnetic resonance imaging (fMRI) of brain activity. The system includes a touch-sensitive tablet, an elevated mounting platform, a stylus, and a controller box, as well as the necessary cabling and software. All equipment residing inside the magnet room is non-ferromagnetic and does not interfere with scanner operation and does not affect fMRI data quality. Individuals lying inside the scanner interact with device in a natural, intuitive way, similar to writing with pen and paper. Drawing motions captured by the tablet are displayed through a pair of fMRI-compatible goggles or by using a projector and screen. Other visual stimuli can be concurrently presented with the drawing motions for the purpose of assessing specific aspects of human behavior. The system allows for a plurality of experiments to be performed, all while brain activity is measured and recorded.08-21-2008
20080200795Method of Modifying MR Signals Using Ultrasound Waves - Described herein is a medical imaging technique that includes directing ultrasound waves into a portion of a body of interest during at least a portion of a time period during which an MR imaging process is simultaneously performed on the portion of the body of interest such that the MR signal is altered by the application of the ultrasound waves. The ultrasound waves may be applied continually during the MR imaging process, or only during a portion thereof. The frequency of the ultrasound waves may be substantially the same as, or different than that of the MR signals. Images may be produced from only the MR imaging process or both the MR imaging process and the application of ultrasound waves prior to the imaging sessions.08-21-2008
20110224535MAGNETIC RESONANCE-ASSISTED BIOPSY EXAMINATION METHOD, AND A MAGNETIC RESONANCE SYSTEM FOR IMPLEMENTING THE METHOD - In a magnetic resonance-assisted biopsy method for a biopsy examination, using magnetic resonance measurement executed by a magnetic resonance measurement unit and a biopsy unit and a computer console, the computer console is located separately from the magnetic resonance measurement unit, the following steps are implemented:09-15-2011
20110275927SYSTEMS AND METHODS FOR STIMULATING AND MONITORING BIOLOGICAL TISSUE - The invention generally relates to apparatuses and methods for stimulating and monitoring biological tissue. In certain aspects, the invention provides a system for stimulating and monitoring tissue, the system including a first energy source, a second energy source, and an imaging device, in which the system is configured such that the first and second energy sources target the same region of tissue and the combined effect of the first and second energy sources stimulates the region of tissue.11-10-2011
20130150703BIOPSY GRID - A biopsy grid is provided that is useful in medical imaging. The biopsy grid comprises a hydrogel layer containing a mixture of contrast agents that are visible in images from X-ray, CT scans, MRI, and/or positron emission tomographs. The hydrogel mixture is attached to a frame having a silicone coated release liner and an adhesive layer. The hydrogel layer is cut into strips that serve as markers in an image. The biopsy grid can be used to locate the position of the marker relative to a tissue of interest in a medical image.06-13-2013
20130150704MAGNETIC RESONANCE IMAGING METHODS FOR RIB IDENTIFICATION - A method for spatially localizing a rib cage prior to transcostal ultrasound treatment of visceral tissue includes computationally refining a three-dimensional model of the rib cage based on image slices taken at multiple locations along the ribs with orientations dependent on local rib orientations.06-13-2013
20130137966TISSUE EXTRACTION SYSTEM AND THREE-DIMENSIONAL DISPLAY METHOD OF THE SAME - A tissue extraction system for extracting tissue from a subject by using an image, wherein the tissue extraction system comprises: an imaging unit for arranging coordinate axes to capture a plurality of sequences; a conversion unit for converting the plurality of sequences captured by the imaging unit into histogram space in which the sequences are described in terms of the coordinate axes; and an extraction unit for extracting the tissue of the subject from the distribution of the histogram converted by the conversion unit.05-30-2013
20130131493METHOD AND APPARATUS FOR PERFORMING DUAL-MODALITY IMAGING - A method for performing an examination of a patient using a dual-modality imaging system includes accessing a list that includes a magnetic resonance imaging (MRI) examination protocol to be used to perform a predetermined MRI examination, the examination protocol including a plurality of MRI protocol actions, receiving an input selecting at least one of the MRI protocol actions, scanning the patient using the MRI examination protocol, scanning the patient using a positron emission tomography (PET) imaging system to acquire PET data, and marking the PET data, using a first visual indication, to indicate the selected MRI protocol action. An imaging system and a non-transitory computer readable medium are also described herein.05-23-2013
20100317962MRI-Guided Devices and MRI-Guided Interventional Systems that can Track and Generate Dynamic Visualizations of the Devices in near Real Time - An MRI-compatible catheter includes an elongated flexible shaft having opposite distal and proximal end portions. A handle is attached to the proximal end portion and includes an actuator in communication with the shaft distal end portion that is configured to articulate the shaft distal end portion. The distal end portion of the shaft may include an ablation tip and includes at least one RF tracking coil positioned adjacent the ablation tip that is electrically connected to an MRI scanner. The at least one RF tracking coil is electrically connected to a circuit that reduces coupling when the at least one RF tracking coil is exposed to an MRI environment. Each RF tracking coil is a 1-10 turn solenoid coil, and has a length along the longitudinal direction of the catheter of between about 0.25 mm and about 4 mm.12-16-2010
20100317961MRI-Guided Devices and MRI-Guided Interventional Systems that can Track and Generate Dynamic Visualizations of the Devices in near Real Time - An MRI-guided medical device includes an elongated sheath, an elongated dilator, and an elongated needle. The sheath has a distal end, an opposite proximal end, and a central lumen extending between the proximal and distal ends. The sheath comprises MRI-compatible material and includes a tracking member located adjacent to the sheath distal end that is visible in an MRI image. The dilator comprises MRI-compatible material and is movably disposed within the sheath lumen. A distal end of the dilator is configured to extend outwardly from the sheath distal end and dilator includes at least one tracking member that is visible in an MRI image. The needle is movably disposed within the dilator lumen and is movable between stored and operative positions relative to the dilator. An RF shield may be coaxially disposed within the elongated sheath so as to surround a portion of the sheath central lumen.12-16-2010
20100317960THERMOTHERAPY DEVICE AND METHOD TO IMPLEMENT THERMOTHERAPY - A thermotherapy device has a transmitter, a receiver and a processing unit. The transmitter is designed to emit a high-energy radiation in a treatment region of a patient. The high-energy radiation exhibits a power that is suitable for thermotherapy. The receiver is designed to detect a sound signal that is generated by the treatment region depending on the high-energy radiation radiated into said treatment region. The processing unit is coupled with the transmitter) and the receiver. The processing unit automatically determines information about the treatment region depending on the detected sound signal.12-16-2010
20130158386SYSTEM FOR ENSURING PRECISION IN MEDICAL TREATMENT - A system for ensuring precision in medical treatment of a patient comprising one or more clusters of targets attached to a patient, a strapping mechanism or a carrier defining a patient-fixed coordinate system. The system also includes a first electro-optical measurement system for observing the one or more clusters of targets and local reference markers of an imaging system to determine the relationship between the patient-fixed coordinate system and a coordinate system of the imaging system, whereby a location to be treated inside the patient can be calculated in the patient-fixed coordinate system. The system further includes a second electro-optical measurement system for observing the one or more clusters of targets and local reference markers of a treatment system, whereby the location to be treated inside the patient can be calculated in a coordinate system of a treatment system.06-20-2013
20120283548METHOD AND DEVICE TO ASSIST A PATIENT IN RE-ASSUMING A DEFINED BREATH HOLD POSITION FOR AN IMAGE ACQUISITION - In a method and device to assist a patient in the resumption of a defined breath hold position for an image acquisition, in particular a magnetic resonance image acquisition, reference data describing the defined breath hold position are acquired in a first breath hold phase by a measurement device, measurement data describing the current breath hold position are acquired with the measurement device and are compared with the reference data in the preparation of an additional breath hold phase, and information describing the deviation of the measurement data from the reference data is emitted by an output device in a humanly-perceptible form.11-08-2012
20130184560GUIDE BLOCK FOR BIOPSY OR SURGICAL DEVICES - A guide block for an MRI device has a block body with a proximal face, a distal face, and a plurality of passageways extending between the two faces. A first guide passageway within the guide block is open along the body length, extends between the proximal face and the distal face, and is configured to receive a tissue-removing device. A second guide passageway within the guide block is open along the body length, extends between the proximal face and the distal face, and is configured to receive the tissue-removing device. A longitudinal opening extends between the first guide passageway and the second guide passageway, and is coextensive with the first guide passageway and the second guide passageway between the proximal face and the distal face.07-18-2013
20130158385Therapeutic Ultrasound for Use with Magnetic Resonance - Therapeutic ultrasound applicator is provided for use with magnetic resonance system. An array of many elements, such as a multi-dimensional array, is used. To avoid cabling, the transmitters are positioned at the array. The array and transmitters are shielded to reduce interference. To avoid large inductors for the many elements, an acoustic matching layer may be sized to provide a desired phase angle or electrical impedance matching.06-20-2013
20130158387MRI THERMAL IMAGING OF WATER TISSUE AND FAT TISSUE USING TRANSVERSE RELAXOMETRY DATA AND PROTON RESONANCE FREQUENCY SHIFT DATA - An apparatus (06-20-2013
20130184559Magnetic Resonance Imaging Compatible Positron Emission Tomography Detector - A compact magnetic resonance imaging compatible positron emission tomography detector. The detector has integrated mechanical and electrical subcomponents. The detector uses a cooling channel which does not interfere with magnetic resonance imaging. The layout and selection of electrical subcomponents of the detector, along with a magnetic resonance compatible cooling strategy, enables the detector to function in a magnetic resonance imaging environment.07-18-2013
20130123609Flexible Coil for MR Experiments on Small Animals - A flexible coil device for supporting imaging experiments on subjects, such as small animals. The device has a rigid part where electronics are accommodated and a flexible loop acting as a receiving coil that picks up the imaging signal. The flexible loop allows its shape to be adapted to the particular shape of the imaged subject at the point of placement. This provides a better filling factor and hence better SNR of the region of interest (ROI). This has the advantage that various imaging applications pose less of a compromise than with rigid coils. The flexible loop can be positioned right against the region of interest (ROI) and so maximises the filling factor and the image SNR.05-16-2013
20110313278METHOD OF MAGNETIC RESONANCE-BASED TEMPERATURE MAPPING - An MRI method (12-22-2011
201301906022D3D REGISTRATION FOR MR-X RAY FUSION UTILIZING ONE ACQUISITION OF MR DATA - Systems and methods for 2D3D registration of apply MR volumes and X-ray images using DRR techniques. A bone classifier is trained from co-registered UTE1, UTE2 and CT prior images. Dual-echo MR UTE1 and UTE2 images are acquired from a patient. The bone structure of the patient is classified and a labeled segmentation is generated. A DRR image is generated from the labeled segmentation and is registered with an X-ray image of the patient. The registration methods are implemented on a processor based system.07-25-2013
20130190603METHOD FOR ULTRASOUND FOCAL SPOT SHAPING - The focus of a focused ultrasound system is calibrated with respect to a frame-of-reference, such as that of a magnetic resonance system, by selectively activating only specific regions of the ultrasound transducer of the ultrasound system, thereby altering the shape of the focus. The focal shape is selectively modified in shape and positioned in successive steps of a calibration procedure, while moving the focus through successive localizers of the frame-of-reference. The parameters for operating the ultrasound system when the calibration procedure is completed are stored as parameters that accurately position the focus of the ultrasound system with respect to the frame-of-reference.07-25-2013
20130190605METHODS AND COMPOSITIONS FOR OBJECTIVELY CHARACTERIZING MEDICAL IMAGES - Methods and compositions are provided for objectively characterizing a pathological lesion in a patient. The method comprises: introducing into the patient a contrast enhancing agent; subjecting the patient to at least one of magnetic resonance imaging and computed tomography to obtain an image; and applying a 3-D autocorrelation function to a subdomain of interest of the image to obtain at least one 3-D autocorrelation spectrum. The method may further comprise comparing the at least one 3-D autocorrelation spectrum to a pre-existing 3-D autocorrelation spectrum that is characteristic for the pathological lesion. In one example, the methods and compositions may be useful for identifying and objectively characterizing amyloid plaque deposits characteristic of Alzheimer's Disease.07-25-2013
20130190606COMBINED QUANTITATIVE MRI AND QUANTITATIVE MRS FOR DIAGNOSIS OF ALZHEIMERS DISEASE AND HIPPOCAMPAL SCLEROSIS - Using both quantitative MRI and quantitative MRS, the inventor demonstrates herein that as age and dementia progress, hippocampal volume (HV), amygdala volume (AV), and NAA/mI ratio all decrease compared to normal controls. The inventor's data also demonstrate herein that NAA/mI vs. total amygdala volume showed a very strong linear correlation, while NAA/mI vs. mean total hippocampal volume had a lesser but still significant correlation. Further, after analyzing the data derived from both quantitative MRI and quantitative MRS methods, the inventor made the surprising discovery that the two tests, when combined, provide significantly improved biomarkers over either alone, and are more effective at early MCI and/or AD diagnosis, as well as HS diagnosis.07-25-2013
20130190604Drive System for a Head Clamp for Use in Imaging by Magnetic Resonance and X-Ray - A head clamp for Magnetic Resonance and X-ray imaging is generally C-shaped including a base and two legs carrying pin clamp members. A course and fine adjustment system allows one of the clamp members to move inwardly relative to the other and then to be finely adjusted so as to apply a clamping force to the skull. The C-shaped support member comprises a truss with a C-shaped inner band adjacent the skull, an outer band generally following the shape of inner band and a plurality of openings defining spaced bars between the inner band and the outer band. The adjustment system comprises a screw that adjusts the width of the C-shaped member at the base and at one leg and includes a gauge to measure force applied with the mechanism located outside the field of view of the head both vertically and horizontally.07-25-2013
20130197350RADIATION FORCE BALANCE CALIBRATOR - A radiation force balance calibrator (08-01-2013
20130197349METHOD FOR CALCULATING A VALUE OF AN ABSORPTION PARAMETER IN POSITRON EMISSION TOMOGRAPHY - A method is disclosed for calculating a spatially resolved value of an absorption parameter for a positron emission tomography (PET) scan of an examination object via magnetic resonance tomography (MRT). Magnetic resonance data is acquired within a first region lying within a field of view of a magnetic resonance system and within a second region bordering on the first and lying at the edge of the field of view. The method includes the spatially resolved calculation of a first value of the absorption parameter from the first MR data within the first region and of a second value from the second MR data within the second region. A three-dimensional parameter map is obtained from the first value. This parameter map is extended by the second value such that within the first region and the second region the parameter map has the value of the absorption parameter in spatially resolved form.08-01-2013
20130197351BEAM DEFLECTION ARRANGEMENT WITHIN A COMBINED RADIATION THERAPY AND MAGNETIC RESONANCE UNIT - In a radiation therapy and magnetic resonance unit, a magnetic resonance diagnosis part is provided with an interior within which a main magnet generates a main magnetic field, the interior being limited in a radio direction about an axis by the main magnet. A radiation therapy part is provided for irradiation of an irradiation area within the interior, said radiation therapy part comprising an electron beam accelerator providing an electron beam parallel to the main magnet field. At least parts of the radiation therapy part comprise the beam deflection arrangement for deflecting the electron beam toward the axis from an initial trajectory parallel to the axis. The beam deflection arrangement comprises a magnetic arrangement providing a first magnetic field in a region of the beam deflection arrangement but of opposite direction and affective to cancel the main magnet field. The second magnet field is directed perpendicular to a trajectory of the electron beam to cause the electron beam to be deflected inward towards the axis.08-01-2013
20130197348CHARGE CONTROL FOR HIGH VOLTAGE THERAPY ENERGY STORAGE COMPONENT - This disclosure provides an implantable medical device comprising a power source a therapy module that includes at least one energy storage component, and a charging module coupled between the power source and the therapy module. The charging module is configured to control charging of the at least one energy storage component of the therapy module. The charging module may be further configured to detect a condition indicative of improper charging, to detect a condition indicative of the implantable medical device being subjected to fields generated by an magnetic resonance imaging (MRI) device, and to terminate charging of the at least one energy storage component when both the condition indicative of improper charging and the condition indicative of the implantable medical device being subjected to fields generated by the MRI device are detected.08-01-2013
20120035462Systems and Methods for Real-Time Tumor Tracking During Radiation Treatment Using Ultrasound Imaging - Systems and methods for tracking a target volume, e.g., tumor, in real-time during radiation treatment are provided. Under one aspect, a system includes an ultrasound probe, an x-ray imager, a processor, and a computer-readable medium that stores a 3D image of the tumor in a first reference frame and instructions for causing the processor to: instruct the x-ray imager and ultrasound probe to substantially simultaneously obtain inherently registered x-ray and set-up ultrasound images of the tumor in a second reference frame; establish a transformation between the first and second reference frames by registering the 3D image and the x-ray image; instruct the ultrasound probe to obtain an intrafraction ultrasound image of the tumor; registering the intrafraction ultrasound image with the set-up ultrasound image; and track target volume motion based on the registered intrafraction ultrasound image.02-09-2012
20120059243MOTION COMPENSATION FOR NON-INVASIVE TREATMENT THERAPIES - Procedures and systems facilitate non-invasive, focused delivery of therapeutic energy to a target within or on a patient using, in various embodiments, a closed-loop approach such that feedback regarding anatomical movement and/or morphology changes is tracked and the uncertainty inherent in the measurements is addressed.03-08-2012
20130204118SYSTEM AND METHOD FOR COLLECTION & USE OF MAGNETIC RESONANCE DATA & MICROWAVE DATA TO IDENTIFY BOUNDARIES OF INTEREST - A system and method for detecting permittivity and conductivity boundaries within a high resolution spatial image of a material is presented. Electrical properties of a material, such as permittivity and conductivity, may assist in identification of physical properties of the material. Structural boundaries within tissue may be identified in spatial images, such as MR images. Image reconstruction algorithms may combine these structural boundaries with microwave images of the tissue to determine the permittivity and conductivity parameters within the structural boundaries. In the case of soft tissue, the microwave images may be captured simultaneously with the spatial images. The microwave images may be taken at a different time from the spatial image for rigid tissue. The method may be employed for two dimensional or three dimensional image reconstruction.08-08-2013
20130204119DEVICE FOR MEASURING KNEE LAXITY - The present invention relates to a device (08-08-2013
20130204121NANOPARTICLE-GUIDED RADIOTHERAPY - The present invention relates to a method and nano-sized particles for image guided radiotherapy (IGRT) of a target tissue. More specifically, the invention relates to nano-sized particles comprising X-ray-imaging contrast agents in solid form with the ability to block x-rays, allowing for simultaneous or integrated external beam radiotherapy and imaging, e.g., using computed tomography (CT).08-08-2013
20130204120EQUIPMENT AND METHODOLOGIES FOR MAGNETICALLY-ASSISTED DELIVERY OF THERAPEUTIC AGENTS THROUGH BARRIERS - Magnetic gradients are used to transport Magnetic Nano Particles through a barrier, for example, the cribiform (also spelled “cribriform”) plate, which is a porous bony structure which separates the nasal cavity from the cranial vault. By utilizing a configuration of magnets (whether of the electromagnetic type or permanent magnets), MNPs can be propelled, pushed, pulled or otherwise manipulated in relation to an anatomical and/or physiological barrier, to position, re-position or maintain the position(s) of the MNPs.08-08-2013
20130204122DEVICE FOR USE IN ELECTRO-BIOLOGICAL SIGNAL MEASUREMENT IN THE PRESENCE OF A MAGNETIC FIELD - A measurement device is presented for use in an EEG measurement performed in the presence of a magnetic field. The device comprises a wiring array for connecting an electrodes arrangement to an electroencephalogram (EEG) monitoring device. The wiring array comprises a plurality of sampling lines arranged to form a first group of sampling lines arranged in a spaced-apart substantially parallel relationship extending along a first axis, at least some of said sampling lines being wire bundles of said first group comprising a plurality of first wires for connecting to a corresponding first plurality of electrodes of said EEG electrodes arrangement; and a second group of sampling lines arranged in a spaced-apart substantially parallel relationship extending along a second axis, intersecting with said first axis, such that said second group of bundles crosses said first group of bundles to form a net structure, at least some of said sampling lines being wire bundles of said second group comprising a plurality of second wires for connecting to a corresponding second plurality of electrodes of said EEG electrodes' arrangement. The wiring array is configured and operable for transmitting a signal measured by the respective electrodes to the EEG monitoring device, enabling generation of EEG data indicative of the neural signal profile along tow directions and characterized by reduced motion artifact and/or reduced gradient artifact associated with the presence of the magnetic field during the EEG measurement.08-08-2013
20120071746MAGNETIC RESONANCE THERMOMETRY USING PRF SPECTROSCOPY - During the thermal treatment of an anatomical zone of interest, tissue temperature within the zone may be determined with a computational model whose parameters are adjusted using spectroscopy-based temperature measurements at interfaces of fat and non-fat tissues.03-22-2012
20120071745PREMATURE NEONATE CLOSED LIFE SUPPORT SYSTEM - A premature neonate closed life support system (NCLSS) including: at least one chamber confining a cradle-like neonate support (CLNS) having suitable dimensions and geometric-configuration for accommodating at least one premature neonate having at least two operational configurations, said operational configurations comprising: a first operational OPEN configuration whereby said CLNS is adapted to couple said neonate to at least one life supporting system by means of at least one life supporting coupling line, prior to positioning said CLNS in a medical device; and a second operational air-tight CLOSED configuration whereby said neonate remains continuously coupled to said at least one life supporting system by means of at least one life supporting coupling line, when positioning said CLNS within said medical device. The OPEN and CLOSED configurations are reversible.03-22-2012
20120095325TREATMENT OF BRAIN DISEASES VIA ULTRASOUND/MAGNETIC TARGETING DELIVERY AND TRACING OF THERAPEUTIC AGENTS - Disclosed herein is a method for treating a brain disease in which focused ultrasound and magnetic targeting are applied to a subject in need of such treatment, so that therapeutic agent-magnetic nanoparticle composites are directed across the blood-brain barrier to a designated locus inside the brain of the subject. Each of the composites includes a magnetic nanoparticle that is formed of an iron-based core and a shell encapsulating the iron-based core, and a therapeutic agent that is bound to the shell of the magnetic nanoparticle. The magnetic nanoparticle has a size ranging from 5 to 200 nm. The iron-based core has a crystalline structure that imparts the composites with a sufficiently high magnetization, thereby enhancing magnetic targeting of the composites to the designated locus inside the brain of the subject. The magnetic targeting treatment is conducted via a magnet providing a magnetic flux density not less than 0.18 T.04-19-2012
20120095324METHOD FOR A NUCLEAR MEDICINE EXAMINATION - A method for a nuclear medicine examination of a patient is disclosed. In at least one embodiment of the method, a magnetic resonance recording of an examination region of the patient is created after a magnetic resonance contrast agent has been administered to the patient. A distribution of the magnetic resonance contrast agent in the examination region is automatically determined from the magnetic resonance recording. After a nuclear medicine tracer has been administered to the patient, a nuclear medicine recording of the examination region of the patient is created. The magnetic resonance contrast agent and the nuclear medicine tracer have essentially identical pharmacokinetic properties. The nuclear medicine recording is corrected as a function of the distribution of the magnetic resonance contrast agent in the examination region.04-19-2012
20120095323Bandpass Sampling for Elastography - The characterization of tissue viscoelastic properties requires the measurement of tissue displacements over a region of interest at frequencies that exceed significantly the frame rates of conventional medical imaging devices. The present invention involves using bandpass sampling to track high-frequency tissue displacements. With this approach, high frequency signals limited to a frequency bandwidth can be sampled and reconstructed without aliasing at a sampling frequency that is lower than the Nyquist rate. With bandpass sampling, it is feasible to use conventional beam-forming on diagnostic ultrasound machines to perform high frequency dynamic elastography. The method is simple to implement as it does not require beam interleaving, additional hardware or synchronization and can be applied to magnetic resonance elastography.04-19-2012
20120095322Devices, systems and methods for multimodal biosensing and imaging - Provided herein are robotic or automated multimodal tissue scanning or imaging systems and methods. The systems comprise a robotic delivery device configured to mechanically scan one or more zones of a tissue by co-registering at least two modalities, i.e., one or more of each of a sensor modality and an imaging modality and acquiring sensor modality data at one or more positions in the zone(s) as the sensor modality is dimensionally translated along the device axes. The system also comprises a computational core of a plurality of interlinked modules for planning, processing, tissue-sampling, visualization, fusion, and control of the delivery device and the system. The methods provided herein utilize the automated systems to produce spatial maps based on the analyzed sensor modality data.04-19-2012
20130211231METHOD AND SYSTEM FOR VISUALIZATION OF TREATMENT VOLUMES - A method for visualization of treatment volumes includes accessing a plurality of images of a region of interest in a subject that are parallel to a plane. The method also includes delineating a cross section of a first treatment volume and a cross section of a second treatment volume in each of the plurality of images. The method includes reconstructing a three dimensional representation of the first and second treatment volumes from the plurality of images based on the delineated cross sections in the plurality of images. The method includes displaying, in a three dimensional image, a portion of the first treatment volume that is located on a first side of a plane and displaying, in the three dimensional image, at least a part of a portion of the second treatment volume that is located on a second side of the plane. The second side is opposite the first side.08-15-2013
20130211232Arthroscopic Surgical Planning and Execution with 3D Imaging - A method includes obtaining a first three-dimensional (3-D) image of a bone structure, generating a surgical plan based on the first 3-D image and registering the surgical plan to the bone structure to generate a registered surgical plan by obtaining a first 2-D real-time video image of the bone structure and a second 3-D image of the bone structure, and correlating structures from the first 2-D real-time video image and the second 3-D image with the surgical plan. The method also includes obtaining a second 2-D real-time image of the bone structure and overlaying the registered surgical plan onto the second 2-D real-time video image.08-15-2013
20130211233INTEGRATED PET/MRI SCANNER - In the integrated PET/MRI scanner provided with an RF coil for MRI and a plurality of PET detectors in the measuring port of the MRI scanner, the PET detectors are disposed with spaces therebetween and at least the transmitting coil elements of the RF coil for MRI are disposed between adjacent PET detectors. Here, the PET detectors are disposed in the circumferential direction of the measuring port with spaces therebetween and the transmitting coil elements are disposed in the axial direction of the measuring port. Alternatively, at least some of the PET detectors are disposed in the axial direction of the measuring port with spaces therebetween and the transmitting coil elements are disposed between adjacent PET detectors. The PET detectors can be DOI-type detectors capable of detecting position in the depth direction.08-15-2013

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