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Determining blood constituent

Subclass of:

600 - Surgery

600300000 - DIAGNOSTIC TESTING

600309000 - Measuring or detecting nonradioactive constituent of body liquid by means placed against or in body throughout test

600310000 - Infrared, visible light, or ultraviolet radiation directed on or through body or constituent released therefrom

Patent class list (only not empty are listed)

Deeper subclasses:

Class / Patent application numberDescriptionNumber of patent applications / Date published
600323000 Oxygen saturation, e.g., oximeter 542
600341000 Inserted in body 11
Entries
DocumentTitleDate
20120203087SYSTEMS AND METHODS FOR MONITORING DEPTH OF CONSCIOUSNESS - During patient monitoring, a depth of consciousness (DOC) measure, such as a bispectral index, may be used in conjunction with additional information obtained from an awareness metric derived from one or more physiological signals, such as a photoplethysmograph signal. In an embodiment, a DOC measure may be combined with information from an awareness metric to produce a combined DOC measure. In an embodiment, information from an awareness metric derived from one or more physiological signals may be used to provide an indication of confidence in a DOC measure. In an embodiment, a DOC measure may be used to provide an indication of confidence in a depth of consciousness assessment based on an awareness metric. In an embodiment, one or the other of a DOC measure and an awareness metric may be used to provide an indication of a patient's depth of consciousness (e.g., by one “overriding” the other).08-09-2012
20110190610OPTICAL SENSOR FOR MEDICAL DEVICE - An optical sensor for a medical device includes a fixed lens spacing between emit and receive modules to achieve target sensor sensitivity, while varying other sensor parameters in order to increase signal amplitude without increasing power demand. The arrangement of an opto-electronic component within an optical sensor receive module is improved by masking the receive module lens with an opaque member to create a masked lens leading edge that is aligned with a leading edge of the opto-electronic component.08-04-2011
20110196215LIVING BODY MONITORING APPARATUS - This living body monitoring apparatus includes an image acquirer which emits light to a living body and acquires a living body image by imaging the living body to which the light is being emitted, a concentration acquirer which acquires a concentration of a blood component of the living body by analyzing the living body image, an information acquirer which acquires information about a change of a circulating blood volume contained in the living body on the basis of the concentration of the blood component, and an output portion which outputs the information about a change of a circulating blood volume.08-11-2011
20090312616Transmission Fluorometer - This disclosure relates generally to a system and method for noninvasive, non-destructive fluorescent measurement. More specifically, the disclosure provides a non-invasive metrology system and method to monitor levels of fluorescent chemicals in the blood. A major application for the invention is field-based non-invasive blood testing for micro-nutrient deficiency and diseases resulting from it, such as Iron deficient anemia. The invention may help reduce or eliminate the need for blood drawing, sending the sample to a blood lab and having to wait for a result.12-17-2009
20100152559APPARATUS AND METHOD FOR NON-INVASIVE AND MINIMALLY-INVASIVE SENSING OF PARAMETERS RELATING TO BLOOD - Medical diagnostic system, apparatus and methods are disclosed. Optical transmitters generate radiation-containing photons having a specific interaction with at least one target chromophore in a target structure, preferably a blood vessel such as the interior jugular vein. The optical transmitters transmit the radiation into at least a first area including a substantial portion of the target structure and into a second area not including a substantial portion of the target structure. Optical receivers detect a portion radiation scattered from at least the first area and the second area. A processor estimates oxygenation, pH or cardiac output based on the scattered radiation detected from the first area, and the scattered radiation from the second area.06-17-2010
20130035569METHOD AND APPARATUS FOR HEMOMETRY - The present invention pertains to a method and apparatus for hemometry in humans. Pressure is applied proximal to a target area in human tissue. A modulated optical signal based on a digital code sequence is transmitted to the target area. A temporal transfer characteristic is derived from the modulated optical signal. Concentration of an analyte is determined based on the temporal transfer characteristic.02-07-2013
20130035568INFORMATION PROCESSING APPARATUS, INFORMATION PROCESSING METHOD, PROGRAM, AND INFORMATION PROCESSING SYSTEM - Provided is an information processing apparatus including a judgment unit for using measurement data in relation to reflectance of light obtained by irradiating a surface of a living body of a subject with light of a predetermined wavelength to judge a condition of a blood vessel and/or a condition of blood flow of the living body in accordance with a color phase corresponding to the reflectance of light.02-07-2013
20100105996FINGER DEPLOYED DEVICE FOR MEASURING BLOOD AND PHYSIOLOGICAL CHARACTERISTICS - The present invention relates to a device for measuring blood and physiological characteristics by passing light through human tissue that is configured for deployment on a human finger. The device includes a lower finger-trough configured in the main housing of the device; a hingedly attached closeable lid that has an upper finger-trough configured for deployment of at least one finger stabilizing element, the lid being latchable in a closed position; a finger stabilizing element made of a material having flexibly soft malleable characteristics so as to sealingly engage the top of the finger; a light source that is deployed in the sloped end wall of the lower finger-trough adjacent to the lower portion of the finger tip; and an end cap the is deployable on the open end of the device when the lid is in the closed position, which enables calibration of the device with a minimum of light wave “noise” from ambient light.04-29-2010
20090326343FLUID HANDLING CASSETTE HAVING A SPECTROSCOPIC SAMPLE CELL - A fluid handling module is configured for removable engagement with a reusable main fluid handling instrument. The module includes a module housing and a first fluid passageway extending from the module housing. The first fluid passageway has a patient end remote from the housing. The first fluid passageway is configured to provide fluid communication with a bodily fluid in a patient. A fluid component separator is in fluid communication with the first fluid passageway. The fluid component separator is configured to separate at least one component from a portion of the bodily fluid drawn from the patient. A spectroscopic sample cell is configured to hold at least a portion of the first component.12-31-2009
20130090540DEVICE FOR CLAMPING A HOSE LINE FOR DETERMINING THE CONCENTRATION OF A BLOOD CONSTITUENT - A device for clamping a hose line for determining the concentration of a constituent of blood in a hose line, in particular in the hose line of an extracorporeal blood circuit of an extracorporeal blood treatment apparatus, includes a clamping unit with two receiving elements and an electric motor-driven actuation mechanism. Actuation mechanism is constituted such that, when a clamping force is applied, the first and second receiving element can be moved from a position releasing the hose line into a position clamping the hose line. Moreover, the device comprises an unlocking mechanism which is constituted such that, by actuating an unlocking element, the actuation mechanism in the position clamping the hose line can be decoupled from electromotive drive. Unlocking mechanism makes it possible for the receiving elements to be transferred easily and rapidly by hand from the position clamping the hose line into the position releasing the hose line.04-11-2013
20090306487PHOTOPLETHYSMOGRAPHY - A photoplethysmograph device includes a light source for illuminating a target object. A modulator drives the light source such that the output intensity varies as a function of a modulation signal at a modulation frequency. A detector receives light from the target object and generates an electrical output as a function of the intensity of received light. A demodulator with a local oscillator receives the detector output and produces a demodulated output,insensitive to any phase difference between the modulation signal and the oscillator, indicative of blood volume as a function of time and/or blood composition. A number of demodulators may be provided to derive signals from multiple light sources of different wavelengths, or from an array of detectors. The plethysmograph may operate in a transmission mode or a reflectance mode. When in a reflectance mode, the device may use the green part of the optical spectrum and may use polarising filters.12-10-2009
20090299160INFORMATION PROCESSING APPARATUS, INFORMATION PROCESSING METHOD, INFORMATION PROCESSING PROGRAM AND RECORDING MEDIUM - An information processing apparatus includes: an internal information acquisition unit for acquiring pieces of information acquired by a measuring tool attached to a subject's head and indicating blood component changes at measurement portions inside the subject's head; a noise removed signal extracting unit for removing noise components of a brain signal on the basis of a reference signal generated on the basis of information indicating blood component changes at a predetermined measurement portion among the acquired pieces of information indicating blood component changes at the measurement portions, the brain signal being generated on the basis of information indicating blood component changes at the measurement portion different from the predetermined measurement portion; and an output unit for outputting the brain signal, from which the noise components are removed, as a signal indicating an activated state at the corresponding measurement portion of a brain surface layer of the subject.12-03-2009
20090247844Detecting Chemical Components From Spectroscopic Observations - Embodiments disclosed herein may include methods and systems capable of estimating the underlying concentrations of chromophores in a sample. The photon scattering and absorption model may be based on Laplace and stable distributions, which may reveal that measurements in diffuse reflectance may follow a Beer-Lambert and Kohlrausch-Williams-Watts (KWW) product. This Beer-Lambert portion of the product may dominate in high absorption sample areas, while the KWW portion of the product may dominate in low absorption sample areas.10-01-2009
20090234206MEDICAL DEVICE FOR DIAGNOSING PRESSURE ULCERS - Medical device or instrument for diagnosing pressure ulcers using optical reflectance spectroscopy. The device may comprise a tip and a controller. The tip is pressed against the skin of the patient and collects the optical reflectance data. The controller processes the data to determine whether there exists a pressure ulcer and, if there is one, its depth. The tip may also include a pressure sensor for sensing the pressure at which the tip is applied to the patient's skin.09-17-2009
20090234205METHOD AND APPARATUS FOR KIDNEY FUNCTION ANALYSIS - A method and apparatus for determining physiological data related to an animal, such as kidney diagnostics data, is provided. The method includes injecting a mixture of a first and a second molecule into an animal (e.g., a human patient), determining a molecular ratio of the molecules, and determining the physiological data based on the molecular ratio. The apparatus includes a number of finger receiving apertures, a light generation circuit, a light detection circuit, a pulse counting circuit, and a user interface.09-17-2009
20090012378Pulsed Lighting Imaging Systems and Methods - Systems and methods for monitoring patients utilizing reflectance avoidance as well as other imaging modalities. Information regarding perfusion, oxygen saturation and oxygen availability, as well as others may be obtained. System embodiments may include a light source, a light transport body configured to project light from the light source to an examination substrate and transmit light reflected by the examination substrate, and an analysis section in optical communication with the light transport body. The light source may be pulsed in order to improve the quality of video images produced by the systems.01-08-2009
20130165756Analyte Sensor - Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.06-27-2013
20120238845ELECTRONIC DEVICE AND METHOD OF USING THE SAME - An electronic device includes an upper layer made of a non-conductive material; a lower layer made of a non-conductive material, wherein at least one of the upper layer and the lower layer is made of a resilient material having a sufficient elasticity such that it will return to an original shape after being deformed, wherein the upper layer comprises an upper conductor and the lower layer comprises a lower conductor and a space is provided between the upper conductor and the lower conductor such that the upper conductor and the lower conductor are not in contact until a force is applied to deform at least one of the upper layer and the lower layer. A sensor device for human body testing connected with the lower conductor, or the lower conductor is configured to function as part of a sensor device for human body testing.09-20-2012
20120238844Method and Apparatus for the Non-Invasive Sensing of Glucose in a Human Subject - An apparatus for a non-invasive sensing of biological analytes in a sample includes an optics system having at least one radiation source and at least one radiation detector; a measurement system operatively coupled to the optics system; a control/processing system operatively coupled to the measurement system and having an embedded software system; a user interface/peripheral system operatively coupled to the control/processing system for providing user interaction with the control/processing system; and a power supply system operatively coupled to the measurement system, the control/processing system and the user interface system for providing power to each of the systems. The embedded software system of the control/processing system processes signals obtained from the measurement system to determine a concentration of the biological analytes in the sample.09-20-2012
20110028808METHOD AND APPARATUS FOR EXAMINATION OF CANCER, SYSTEMIC LUPUS ERYTHEMATOSUS (SLE), OR ANTIPHOSPHOLIPID ANTIBODY SYNDROME USING NEAR-INFRARED LIGHT - An object of the present invention is to provide apparatuses for examining/diagnosing clinical disease of cancer, systemic lupus erythematosus (SLE), or antiphospholipid antibody syndrome. Blood, blood-derived component, urine, sweat, nail, skin, or hair is irradiated with light having a wavelength of 400 to 2,500 nm or a part of the range, of which the reflection light, the transmission light, or the transmission reflection light is then detected to give spectroscopic absorbance data, and afterward a previously prepared analysis model is used to analyze the absorbance over the whole wavelengths or at a specific wavelength for the measurement to allow the achievement of the object.02-03-2011
20090326342METHOD, ARRANGEMENT AND SENSOR FOR NON-INVASIVELY MONITORING BLOOD VOLUME OF A SUBJECT - A method, arrangement and sensor for monitoring blood status of a subject are disclosed. In-vivo measurement signals indicative of absorption caused by blood are acquired at a plurality of measurement wavelengths. Based on the in-vivo measurement signals, successive values are determined for a hemoglobin parameter indicative of the concentration of hemoglobin in the blood of the subject and the blood volume status of the subject is monitored based on the successive values. The monitoring may involve determining the absolute value of the blood volume or relative changes in the blood volume. In one embodiment, the absolute value of the blood volume is indicated continuously together with hemoglobin concentration and composition.12-31-2009
20100292547SYSTEM AND METHOD FOR NON-INVASIVE PHOTOTHERMAL RADIOMETRIC MEASUREMENT - There is provided a glucose monitoring method and apparatus based on the principle of Wavelength-Modulated Differential Laser Photothermal Radiometry (WM-DPTR). Two intensity modulated laser beams operating in tandem at specific mid-infrared (IR) wavelengths and current-modulated synchronously by two electrical waveforms 180 degrees out-of-phase, are used to interrogate the tissue surface. The laser wavelengths are selected to absorb in the mid infrared range (8.5-10.5 μm) where the glucose spectrum exhibits a discrete absorption band. The differential thermal-wave signal generated by the tissue sample through modulated absorption between two specific wavelengths within the band (for example, the peak at 9.6 and the nearest baseline at 10.5 μm) lead to minute changes in sample temperature and to non-equilibrium blackbody radiation emission. This modulated emission is measured with a broadband infrared detector. The detector is coupled to a lock-in amplifier for signal demodulation. Any glucose concentration increases will be registered as differential photothermal signals above the fully suppressed signal baseline due to increased absorption at the probed peak or near-peak of the band at 9.6 μm at the selected wavelength modulation frequency. The emphasis is on the ability to monitor blood glucose levels in diabetic patients in a non-invasive, non-contacting manner with differential signal generation methods for real-time baseline corrections, a crucial feature toward precise and universal calibration (independent of person-to-person contact, skin, temperature or IR-emission variations) in order to offer accurate absolute glucose concentration readings.11-18-2010
20110046460METHOD AND MEASUREMENT DEVICE FOR RECORDING MEASUREMENT SIGNALS FROM VITAL TISSUE - The invention is directed to a measuring method and apparatus for taking spectrometric readings from vital tissue. The object of the invention is to provide solutions by which, in the course of a spectrometric measurement, it is possible to generate measurement values that, compared to above-described previous recording methods, provide more comprehensive information. According to the invention, this object is attained by a method that generates spectrometric signals and in which light is directed into a sample of vital tissue to be examined, remission light exiting the tissue sample to be examined is fed to a spectrometer, and the spectrometer generates output signals that represent the intensity of the remission light with respect to the wavelength, the measurement being performed in such a manner that it extends over a period of time during which the presence of hemoglobin in the examined tissue sample is actively changed by changing pressure on the tissue, wherein the spectra determined in succession for different tissue pressures are used in order to determine changes in the spectra induced by the hemoglobin concentration, and, from these different spectra, the concentrations of selected substances in the tissue sample are calculated. In this manner, it is advantageously possible to generate, in relatively quick succession, a plurality of spectra relating to the tissue sample under examination, wherein these spectra have differences (“distortions”) caused by actively induced changes of pressure on the tissue, and the differences are sufficient for determining the concentration of substances to be detected in the vascular parts of the tissue system.02-24-2011
20080269577INSTRUMENT FOR MEASURING CARBON MONOXIDE POISONING OF HUMANS USING IN VIVO NIRS TECHNOLOGY - Spectral, frequency based non-invasive procedure for determination of blood constituents utilizing in vivo NIRS (Near-Infrared Spectrum) technology, which is the measurement of the near-infrared absorption spectrum within a region of the living human body for the purpose of identifying tissue and blood components and their concentrations and more particularly to novel applications and methodology for determining the optical response, measurements and calculations relating to the concentrations of individual chromophores in the bloodstream and particularly to the level of CO chromophores in the tissues of an animal or human being.10-30-2008
20110288387Transmissivity adjustment apparatus, observation apparatus and obsevation system - Using a transmittance adjusting device decreasing a transmittance of at least from 460 nm to 500 nm, which is a wavelength range between a point of end of a first optical absorption peak of hemoglobin and a point of start of a second optical absorption peak of hemoglobin, to between 20% and 70% for illuminating light from an illuminating light supply section or reflected light from an object, during observation of the inside of a body cavity, enhanced display of vessels with color reproduction that has no difference from that in observation under visible light, enabling color reproduction similar to that in observation under visible light and further enhanced display of vessels.11-24-2011
20100268042CONFOCAL PHOTOACOUSTIC MICROSCOPY WITH OPTICAL LATERAL RESOLUTION - A confocal photoacoustic microscopy system includes a laser configured to emit a light pulse, a focusing assembly configured to receive the light pulse and to focus the light pulse into an area inside an object, an ultrasonic transducer configured to receive acoustic waves emitted by the object in response to the light pulse, and an electronic system configured to process the acoustic waves and to generate an image of the area inside the object. The focusing assembly is further configured to focus the light pulse on the object in such a way that a focal point of the focusing assembly coincides with a focal point of the at least one ultrasonic transducer.10-21-2010
20100099961METHOD FOR DETERMINING MICROVASCULAR LESIONS - The invention relates to a method for determining microvascular diseases wherein, first, a volume pulse development of a first blood constituent of the blood in a blood path is determined, and a volume pulse development of a second blood constituent in a blood path, being different from the first blood constituent, is determined. Thereafter, comparable reference points in the volume pulse development of the first blood constituent and in the volume pulse development of the second blood constituent are determined. Then, there is determined a temporal difference (Δt) of the determined reference points in the volume pulse developments of the first blood constituent and the second blood constituent.04-22-2010
20100125187Blood constituent concentration detector and starter for transporter - A blood constituent concentration detector includes: a detection portion having an optical window for measuring a blood constituent concentration of a part, of a living body in an optical manner when the part of the living body is pressed on the detection portion; a load determination element for determining whether a load to the detection portion is equal to or larger than a first threshold, and smaller than a second threshold, wherein the second threshold is larger than the first threshold; and a measurement element for measuring the blood constituent concentration when the load determination element determines that the load to the detection portion is equal to or larger than the first threshold, and smaller than the second threshold.05-20-2010
20090088616Ultrasonic Diagnostic Apparatus - There is provided an optical bioinstrumentation device, with which measurement data reflect more correctly the information inside the living body with less noise even the subject moves when the information inside the living body is measured by using the light.04-02-2009
20080208018Apparatuses for Noninvasive Determination of in vivo Alcohol Concentration using Raman Spectroscopy - Methods and apparatuses for the determination of an attribute of the tissue of an individual use non-invasive Raman spectroscopy. For example, the alcohol concentration in the blood or tissue of an individual can be determined non-invasively. A portion of the tissue is illuminated with light, the light propagates into the tissue where it is Raman scattered within the tissue. The Raman scattered light is then detected and can be combined with a model relating Raman spectra to alcohol concentration in order to determine the alcohol concentration in the blood or tissue of the individual. Correction techniques can be used to reduce determination errors due to detection of light other than that from Raman scattering from the alcohol in the tissue. Other biologic information can be used in combination with the Raman spectral properties to aid in the determination of alcohol concentration, for example age of the individual, height of the individual, weight of the individual, medical history of the individual and his/her family, ethnicity, skin melanin content, or a combination thereof. The method and apparatus can be highly optimized to provide reproducible and, preferably, uniform radiance of the tissue, low tissue sampling error, depth targeting of the tissue layers or sample locations that contain the attribute of interest, efficient collection of Raman spectra from the tissue, high optical throughput, high photometric accuracy, large dynamic range, excellent thermal stability, effective calibration maintenance, effective calibration transfer, built-in quality control, and ease-of-use.08-28-2008
20100280343MULTIPLE WAVELENGTH PHYSIOLOGICAL MEASURING APPARATUS, SENSOR AND INTERFACE UNIT FOR DETERMINATION OF BLOOD PARAMETERS - A measuring apparatus, a physiological sensor, and an interface unit for determining blood parameters of a subject are disclosed. The sensor comprises an emitter unit comprising a first plurality of emitter elements configured to emit radiation at a second plurality of wavelengths and a detector unit configured to receive radiation generated by the emitter unit and transmitted through tissue of the subject. The sensor further comprises a sensor memory storing sensor-specific information about the sensor unit, wherein the sensor-specific information includes at least calibration data for a given measurement mode, and a memory access interface for enabling an entity external to the sensor to update at least part of the sensor-specific information in a sensor ability update process, thereby to update ability of the sensor unit to operate in the given measurement mode.11-04-2010
20080281173Noninvasive blood analysis by optical probing of the veins under the tongue - A method for analysis of blood components or parameters is disclosed where a probe having an excitation outlet and a response inlet is placed in proximity to or in contact with a tissue of an underside of a patient's tongue over a big vein in the tongue so that an excitation signal exits the outlet, produces a response which enters the inlet for detection and analysis.11-13-2008
20080269578Method for Detecting an Analyte Within the Body of a Patient or an Animal - The invention relates to a method for detecting an analyte within tissue of a patient or an animal. In the laboratory medicine it is often necessary to determine the amount of analytes within body fluids such as blood. For that purpose a blood withdrawal is carried out by experienced medical personnel, and the blood is analysed in the laboratory. This ex-vivo measurement of analytes is uncomfortable for the patient. Moreover, there is an unwanted delay between the blood withdrawal and the time at which the measurement values are obtained from the laboratory. In order to avoid these disadvantages it is suggested to detect analytes 10-30-2008
20100004520Method and Apparatus for Foreign Matter Detection For Blood Content Sensors - Apparatus and methods for detecting and removing foreign matter on an in vivo blood content sensor window utilizing time and wavelength techniques to provide more beneficial information to an operator to facilitate for more accurate blood content readings.01-07-2010
20090005661Non-invasive blood component measuring device and non-invasive blood component measuring method - A non-invasive blood component measuring device comprising: a light source section for irradiating a light to a blood vessel through a skin; an imaging section for imaging the irradiated blood vessel through the skin; and a controller, including a memory under control of a processor, the memory storing instructions enabling the processor to carry out operations, comprising: creating a concentration profile based on an image obtained by imaging the blood vessel with the imaging section; calculating a blood component concentration based on the concentration profile; acquiring a shape feature of the concentration profile; and correcting the blood component concentration based on the shape feature of the concentration profile is disclosed. A non-invasive blood component measuring method is also disclosed.01-01-2009
20080319289Antigen monitoring system - A method for detecting cancer in a subject includes administering polysilicon mirrors to the subject, transmitting near infrared light through subject's skin, receiving light which is reflected from the polysilicon mirrors though the subject's skin, converting received light into a digital signal and calculating a level of CEA in the subject's blood from the digital signal.12-25-2008
20090326344System and Method for Optical Continuous Detection of an Analyte In Bloodstream - A method for performing a blood assay includes the steps of positioning an optical biosensor in fluid communication with a blood vessel whereby blood from the blood vessel contacts the biosensor. The biosensor includes at least one material adapted to bind to an analyte. The method also includes the steps of detecting a change in at least one optical property of the biosensor resulting from binding of the at least one material with the analyte and transmitting a continuous signal representative of the change in at least one optical property of the biosensor to a display module to provide real time analysis by a clinician.12-31-2009
20090203976Non-invasive blood component measuring device, non-invasive blood component measuring method, and a computer program product - A noninvasive blood component measuring device configured so as to resolve the variance of measuring results depend on the fixing position to the living body. Concretely, a non-invasive blood component measuring device comprising a light source section for illuminating a living body which includes a blood vessel, an imaging section for imaging the living body illuminated by the light source, and a controller is disclosed. The controller includes a memory under control of a processor. The memory stores instructions enabling the processor to carry out following operations: calculating a blood component concentration based on a blood vessel in a living body image obtained by the imaging section imaging a living body; determining the position of the blood vessel in the living body image; preparing at least a first luminance distribution which is distributed along the blood vessel based on the position of the blood vessel; obtaining an index which reflects the amount of blood contained in the peripheral tissue of the blood vessel based on the first luminance distribution; and correcting the blood component concentration based on the index. Non-invasive blood component measuring method and a computer program product capable of achieving above mentioned function are also disclosed.08-13-2009
20080262325TISSUE PROFILE WELLNESS MONITOR - A tissue profile wellness monitor measures a physiological parameter, generates a tissue profile, defines limits and indicates when the tissue profile exceeds the defined limits. The physiological parameter is responsive to multiple wavelengths of optical radiation after attenuation by constituents of pulsatile blood flowing within a tissue site. The tissue profile is responsive to the physiological parameter. The limits are defined for at least a portion of the tissue profile.10-23-2008
20090247845System And Method For Estimating Blood Analyte Concentration - There is provided a system and method for estimating blood analyte concentration using a non-invasive medical device. The method includes detecting light from a plurality of light sources and generating signals representative of observed absorption of the light from the plurality of light sources. Blood analyte concentrations are then estimated using support vector regression analysis.10-01-2009
20100160750SYSTEM AND METHOD FOR NON-INVASIVE SPECTROSCOPIC DETECTION FOR BLOOD ALCOHOL CONCENTRATION - An apparatus and method for acquiring and analyzing a spectroscopic sample for a substance from a sampling region of the tissue of a person at an interstitial region between the fingers of the person, by way of a probe and a spectroscopic detector for radiating the interstitial region with electromagnetic radiation and analyzing a diffuse-reflectance signal obtained from the tissue at the sampling region. The apparatus preferably also incorporates a biometric sensor to perform a verification of the person.06-24-2010
20090318786CHANNELED TISSUE SAMPLE PROBE METHOD AND APPARATUS - Sampling is controlled in order to enhance analyte concentration estimation derived from noninvasive sampling. More particularly, sampling is controlled using controlled fluid delivery to a region between a tip of a sample probe and a tissue measurement site. The controlled fluid delivery enhances coverage of a skin sample site with the thin layer of fluid. Delivery of contact fluid is controlled in terms of spatial delivery, volume, thickness, distribution, temperature, and/or pressure.12-24-2009
20110112386NONINVASIVE ALCOHOL SENSOR - The present invention provides a noninvasive alcohol sensor that measures ethanol concentration with high accuracy by suppressing error dependent on glucose concentration. An alcohol sensor 05-12-2011
20110028809PATIENT MONITOR AMBIENT DISPLAY DEVICE - Embodiments of the disclosure include an orb or lamp communicating with a noninvasive monitor to provide a readily identifiable point indication of a wellness of a monitored patient. In an embodiment the orb emits a color gradient from a first color through at least two other colors responsive to values of a wellness measurement. Exemplary wellness indications include one or a statistical combination of blood constituent measurements, combinations of other physiological parameters, or the like.02-03-2011
20080275320METHOD AND DEVICE FOR MEASUREMENTS IN BLOOD - We present an optical probe arrangement that surrounds blood in a receptacle. It comprises LED's and light detector arranged to overcome the variations when the receptacle is translucent medical tubing and the like. Also, a signal processing algorithm is used to average signals from a plurality of light detectors, to further enhance results when measuring hematocrit. The invention makes it possible to add the feature of hematocrit measurement into dialysis system without major alterations to the dialysis machine or transport tubing.11-06-2008
20110004081METHODS AND APPARATUS FOR DETERMINING BREATHING EFFORT CHARACTERISTIC MEASURES - One or more respiratory characteristics of a patient are measured by coupling patient monitor apparatus (e.g., a photoplethysmograph (“PPG”)) to the patient in order to produce a patient monitor signal that includes signal indicia indicative of effort the patient is exerting to breathe. A breathing or respiratory effort signal for the patient is extracted from the patient monitor signal. A respiratory characteristic signal is extracted (at least in part) from the effort signal. This may be done, for example, on the basis of an amplitude feature of the effort signal and a relative time of occurrence of that amplitude feature. Alternatively, the respiratory characteristic signal may be based on a relationship between two amplitude features of the effort signal, with or without regard for specifics of the times of occurrence of those amplitude features. A breath air flow meter may also be coupled to the patient, if desired, in order to produce a flow signal. One or more of the respiratory characteristic measures may also be partly based on the flow signal.01-06-2011
20100217103Ear sensor - An ear sensor provides a sensor body having a base, legs extending from the base and an optical housing disposed at ends of the legs opposite the base. An optical assembly is disposed in the housing. The sensor body is flexed so as to position the housing over a concha site. The sensor body is unflexed so as to attach the housing to the concha site and position the optical assembly to illuminate the concha site. The optical assembly is configured to transmit optical radiation into concha site tissue and receive the optical radiation after attenuation by pulsatile blood flow within the tissue.08-26-2010
20090216096METHOD AND APPARATUS TO DETERMINE SKIN STEROL LEVELS - A method and apparatus is provided for measuring a sterol, such as cholesterol, deposited in the skin. Light of two or more wavelengths is emitted toward or into a skin sample and the light is differentially absorbed by the sterol in the skin sample. The differentially absorbed light is detected and the amount of sterol in the skin sample is determined based on the differential absorption.08-27-2009
20110152648PULSE OXIMETER SENSOR - A method of sensing or measuring various characteristics of blood is disclosed. The method includes providing a sensor having an emitter and a receiver coupled to external processing apparatus. The sensor has a generally elongated configuration designed to be formed into a generally U-shaped orientation so that the sensor can be positioned over the skin of a patient adjacent the patient's mouth with the emitter and receiver in an aligned orientation on opposite sides of the skin. One of the emitter and receiver is positioned against the skin outside of the mouth and the other is positioned against the skin on the inside of the mouth. The sensor is used to sense or measure at least one selected characteristic of the blood of the patient.06-23-2011
20120203088BIOLOGICAL OPTICAL MEASUREMENT INSTRUMENT AND REFERENCE IMAGE DISPLAY METHOD - The biological optical measurement instrument is provided with a mobile position sensor that can move in a 3-dimensional space and that detects spatial position in the 3-dimensional space, a head-surface image creating unit that creates a head-surface image of an object and a head-surface point creating unit that creates, on the head-surface image, a head-surface point corresponding to the spatial position of the mobile position sensor.08-09-2012
20100280342MULTIPLE WAVELENGTH PHYSIOLOGICAL MEASURING APPARATUS, SENSOR AND INTERFACE UNIT FOR DETERMINATION OF BLOOD PARAMETERS - A measuring apparatus, a physiological sensor, and an interface unit for determining blood parameters of a subject are disclosed. The sensor comprises an emitter unit comprising a first plurality of emitter elements configured to emit radiation at a second plurality of wavelengths and a detector unit configured to receive radiation generated by the emitter elements and transmitted through the tissue of the subject, wherein the detector unit is further configured to produce electric measurement signals indicative of absorption caused by the blood of the subject. In order to make the sensor compatible with a variety of different monitoring units, the sensor or the interface unit is provided with a memory that stores emitter activation information for at least a third plurality of wavelengths, thereby to enable a monitoring unit operably connectable to the physiological sensor to employ a combination of wavelengths selected from the third plurality of wavelengths, wherein the third plurality is equal to or smaller than the second plurality.11-04-2010
20090118602Disease Diagnosis Support System - There is provided a system for supporting the assessment as to which disease group the subject to be examined falls in or what position in the whole disease group the subject is in. This support system comprises the data storage part which stores feature values of optical bio-measurement data of many subjects including patients in multiple disease groups, the analysis part which extracts plural kinds of feature values from the optical bio-measurement data and the display part which displays the results of analysis in the analysis part associated with the dictionary data, wherein the display part produces a scatter diagram on which features values of the dictionary data are plotted, with one of the two feature values being plotted along the axis of abscissa and the other along the axis of ordinate, and displays the positions of the subject to be assessed on the scatter diagram superimposed on the scatter diagram. With this scatter diagram, the relationship between the features of the subject and the feature of the disease group can be known in one glance.05-07-2009
20110054278EMITTER DRIVER FOR NONINVASIVE PATIENT MONITOR - Embodiments of the present disclosure include an emitter driver configured to be capable of addressing substantially 2N nodes with N cable conductors configured to carry activation instructions from a processor. In an embodiment, an address controller outputs an activation instruction to a latch decoder configured to supply switch controls to activate particular LEDs of a light source.03-03-2011
20110118572METHOD AND APPARATUS FOR TOTAL HEMOGLOBIN MEASUREMENT - The present invention pertains to a method and apparatus for total hemoglobin measurement. A modulated optical signal based on a digital code sequence is transmitted to human tissue. A temporal transfer characteristic is derived from the modulated optical signal. Total hemoglobin is determined based on the temporal transfer characteristic.05-19-2011
20110201908INTERMITTENT EXTRACORPOREAL SPECTROPHOTOMETRY - An apparatus for intermittent measurement of blood parameters using spectrophotometry is provided. In exemplary embodiments, blood is temporarily withdrawn from the patient and passed through a cuvette, allowing spectrophotometric analysis. This blood may then immediately returned to the patient in a sterile fashion. The technique allows for real-time analysis of blood at the bedside without delays in transportation and laboratory analysis. In exemplary embodiments, there is no blood loss, so measurements can be repeated frequently with no detriment to the patient. In exemplary embodiments, the spectrophotometer is detachable from the cuvette and does not come in contact with blood, such that it can be used for multiple patients with minimal cost. The apparatus may be used to measure the oxygen saturation of blood and hemoglobin concentration, although it could be easily adapted to measure these and many other parameters simultaneously.08-18-2011
20110201909ANALYTE DETECTION DEVICES AND METHODS WITH HEMATOCRIT-VOLUME CORRECTION AND FEEDBACK CONTROL - Disclosed are devices, arrangements and methods for quantifying the concentration of an analyte present in bodily fluid, including: an assay pad having at least one chemical reagent capable of producing a detectable signal in the form of a reaction spot upon reaction with the analyte; a light source; a detector array; a processor; and a memory in communication with the processor, the memory comprising: (a) at least one value indicative of one or more of: (i) the level of hematocrit contained in the sample; (ii) the volume of the sample applied to the assay pad; or (iii) imperfections present in the reaction spot; and (b) at least one algorithm for calculating the concentration of the analyte contained in the sample.08-18-2011
20100030041MULTI-STREAM EMITTER FOR NONINVASIVE MEASUREMENT OF BLOOD CONSTITUENTS - The present disclosure relates to an emitter that is suitable for a noninvasive blood constituent sensor. The emitter is configured as a point optical source that comprises a plurality of LEDs that emit a sequence of pulses of optical radiation across a spectrum of wavelengths. In some embodiments, the plurality of sets of optical sources may each comprise at least one top-emitting LED and at least one super luminescent LED. In some embodiments, the emitter comprises optical sources that transmit optical radiation in the infrared or near-infrared wavelengths suitable for detecting glucose. In order to achieve the desired SNR for detecting analytes like glucose, the emitter may be driven using a progression from low power to higher power. In addition, the emitter may have its duty cycle modified to achieve a desired SNR.02-04-2010
20100298675Hemoglobin Display and Patient Treatment - The present disclosure describes embodiments of a patient monitoring system and methods that include the measure and display of hemoglobin statistics. In an embodiment, total hemoglobin trending is displayed over a period of time. Statistics can include frequency domain analysis, which may be unique for each patient monitored. The total hemoglobin trending and/or statistics can further be used to help control the treatment of a patient, such as being used to control IV administration.11-25-2010
20100160751PHOTOPLETHYSMOGRAPHIC SENSOR BASED BLOOD GAS MONITOR DEVICE FOR ANALYSIS, RESEARCH AND CALIBRATION IN AN EXTRACORPOREAL CIRCUIT OR EXTRACORPOREAL PULSE SIMULATION SYSTEM - A blood oxygenation monitoring device may comprise an extracorporeal pulse simulation system including one at least partially transparent blood holding element with a photoplethysmographic sensor coupled to the element and adapted to measure particular gas content of the blood. The system includes a pulse simulation mechanism configured to simulate pulsatile behavior of the blood within the element relative to the photoplethysmographic sensors. The blood holding element may be a reservoir, wherein the pulse simulation mechanism includes a magnetic stirrer and stir bar within the reservoir. The blood holding member may be flexible tubing having blood flow there through, wherein the pulse simulation mechanism is a peristaltic pump coupled to the tubing. The monitoring device can rapidly and accurately form oxygen dissociation curves. The monitoring device can be utilized in conjunction with a heart lung bypass machine or other extra corporeal circuit devices or can be a calibration tool for sensors.06-24-2010
20120209096NASAL AND ORAL PATIENT INTERFACES - A patient interface for communicating fluids to and/or from a patient's nasal cavity and/or oral cavity is disclosed. In addition, a patient interface for fluid and physiological function monitoring proximate to the patient's nasal cavity and/or oral cavity is disclosed. An apnea monitor and a method for monitoring apnea are also disclosed.08-16-2012
20120310058PHOTON DENSITY WAVE BASED DETERMINATION OF PHYSIOLOGICAL BLOOD PARAMETERS - A system for measuring a physiological parameter of blood in a patient is presented. The system includes a transmission module configured to emit a plurality of photon density waves into tissue of the patient from a plurality of modulated light sources. The system also includes a receiver module configured to detect characteristics of the plurality of photon density waves. The system also includes a processing module configured to identify characteristics of a pulsatile perturbation of the tissue based on the characteristics of the plurality of photon density waves, and identify a value of the physiological parameter based on at least the characteristics of the pulsatile perturbation of the tissue and the characteristics of the plurality of photon density waves.12-06-2012
20120209095SENSOR, APPARATUS AND METHOD FOR NON-INVASIVELY MONITORING BLOOD CHARACTERISTICS OF A SUBJECT - A sensor, apparatus and method for non-invasively monitoring blood characteristics of a subject are disclosed. The sensor comprises an emitter unit configured to emit radiation through the tissue of the subject at a plurality of measurement wavelengths and a detector unit that comprises photo detectors. To achieve a simple sensor assembly, the photo detectors are together adapted to receive the radiation at the plurality of wavelengths and to produce in-vivo measurement signals corresponding to the plurality of measurement wavelengths, the in-vivo measurement signals being indicative of absorption caused by blood of the subject. Furthermore, the photo detectors are mounted so that optical paths from the emitter unit to the photo detectors are different, and the plurality of wavelengths are divided between the photo detectors so that two spectrally adjacent photo detectors have at least one common wavelength. The apparatus comprises a path normalization unit configured to normalize the in-vivo measurement signals to an optical path specific to one of the photo detectors.08-16-2012
20110092784ADJUSTABLE CONNECTOR AND DEAD SPACE REDUCTION - Methods and systems for determining the concentration of one or more analytes from a sample such as blood or plasma are described. The systems described herein can be configured to withdraw a certain volume of sample from a source of bodily fluid, direct a first portion of the withdrawn sample to an analyte monitoring system and return a second portion of the sample to the patient. The analyte monitoring system can be connected to the source of bodily fluid via a connector that is configured to maintain uniform velocity across the connector and reduce the dead space volume.04-21-2011
20100094107REFLECTION-DETECTOR SENSOR POSITION INDICATOR - A reflection-detector sensor position indicator comprises emitters that transmit light having a plurality of wavelengths. A detector outputs a sensor signal. At least one reflection detector outputs at least one sensor position signal. An attachment assembly attaches the emitters, the detector and the reflection detector onto a tissue site. A sensor-on condition indicates that the attachment assembly has positioned the emitters generally centered over a fingernail, the detector on a fingertip opposite the fingernail and the reflection detector over the fingernail. The sensor signal, in the sensor-on condition, is at least substantially responsive to the emitter transmitted light after attenuation by pulsatile blood flow perfused within a fingernail bed underneath the fingernail. The sensor position signal, in the sensor-on condition, is at least substantially responsive to the emitter transmitted light after reflection off of the fingernail.04-15-2010
20110112385APPARATUS AND METHOD FOR DATING A BODY SAMPLE - A method and apparatus for dating a body sample, for example a sample of body fluid involves taking a series of spectroscopic measurements of the sample, each measurement in the series including at least two predetermined positions in the spectrum. The positions have spectral characteristics corresponding to two or more predetermined substances present in the sample that have a time varying relationship with each other. The measurements in the series are spaced in time. A concentration of each of the substances present in the sample is then determined from each of the spectroscopic measurements at each point in time. Next, a ratio of the concentrations of the two predetermined substances at each point in time is determined and then the ratios of the concentrations of the two predetermined substances over time are analysed to estimate when the concentrations of the two substances were at a limit of their concentrations, thereby providing an indication of the age of the sample. The sample may be blood, which may be either within the body (e.g. as a bruise), or external to the body.05-12-2011
20120165628System and method for reliable sleep diagnostic testing - A method for securely affixing a sensor to a patient is provided. The method includes attaching the sensor to the patient's index finger with a sensor signal cable routed along the patient's hand, and configuring an identification band to encircle the signal cable and the patient's wrist using a secure affixing arrangement. The identification band is configured to evidence tampering when removed. The secure affixing arrangement may take various forms, including tying loops and securing the cable and/or sensor to the patient using tape, plastics, and so forth.06-28-2012
20120220841MEDICAL SENSOR USING PHOTONIC CRYSTAL LED - Systems and methods are provided for spectrophometric measurement of a physiological property of a patient. For example, an embodiment of a patient monitoring system may include a monitor operatively coupled to a spectrophotometric sensor, which may include an emitter configured to transmit light into tissue of the patient and a detector configured to receive the light from the tissue. The emitter may use a photonic crystal light emitting diode to generate the light.08-30-2012
20090264720Wearable Automated Blood Sampling and Monitoring System - A wearable blood chemistry monitoring device is disclosed which comprises a wearable automated blood chemistry monitoring device comprising (A) a mini pump which can be, for example a peristaltic pump or syringe pump; (B) a portable form factor mechanical apparatus which preferably includes a rotatable disc with a hole which fits over the pump; (C) at least one measurement element for measuring at least one blood parameter, preferably on the disc, and preferably a series of glucose strips arranged radially in a spoke-like pattern on the disc; (D) a catheter connected to the pump via a tube; (E) a computerized device adapted to automatically measure blood analytes and blood parameters; (F) a belt adapted to hold the housing, a waste bag, and a flush solution bag; wherein the pump and disk are arranged in the housing so that a hole in a disk fits over the pump.10-22-2009
20100010326CONTOURED PROTRUSION FOR IMPROVING SPECTROSCOPIC MEASUREMENT OF BLOOD CONSTITUENTS - A noninvasive physiological sensor for measuring one or more physiological parameters of a medical patient can include a bump interposed between a light source and a photodetector. The bump can be placed in contact with body tissue of a patient and thereby reduce a thickness of the body tissue. As a result, an optical pathlength between the light source and the photodetector can be reduced. In addition, the sensor can include a heat sink that can direct heat away from the light source. Moreover, the sensor can include shielding in the optical path between the light source and the photodetector. The shielding can reduce noise received by the photodetector.01-14-2010
20120253150MULTI-STREAM SENSOR FOR NONINVASIVE MEASUREMENT OF BLOOD CONSTITUENTS - The present disclosure relates to a sensor having a set of photodetectors that are arranged at various locations to enable the measurement of blood glucose. The photodetectors are arranged across multiple locations. For example, the detector may comprise multiple photodetector arrays that are arranged to have a sufficient difference in mean path length to allow for noise cancellation and noise reduction. Walls may be used in the detector to separate individual photodetectors and prevent mixing of detected optical radiation between the different locations on the measurement site. A window may also be employed to facilitate the passing of optical radiation at various wavelengths for measuring glucose in the tissue.10-04-2012
20120253149METHOD AND APPARATUS FOR NON-INVASIVE PHOTOMETRIC BLOOD CONSTITUENT DIAGNOSIS - A non-invasive method and apparatus utilizing a single wavelength (800 nm, isobestic) for the instantaneous, reflective, non-pulsatile spatially resolved reflectance system, apparatus and mathematics that allows for the correct determination of critical photo-optical parameters in vivo. Transcutaneous blood constituent (analyte or drug level) measurements can be determined in real-time. The “closed-form” nature of the mathematics allows for immediate calculations and real-time display of Hematocrit and other pertinent blood values in a variety of handheld or other like devices.10-04-2012
20090018420Apparatus for Non-Invasive Spectroscopic Measurement of Analytes, and Method of Using the Same - An apparatus for spectroscopic evaluation of a subject's body fluids may be used at the interstitial region adjacent to or in between a subject's extremities using a spectroscopic probe. The spectroscopic probe may possess one or more of the movements such as rotational, translational, and/or vertical freedom necessary for the probe to contact the subject's tissue at a consistent angle and pressure while accommodating the different size of the subject's extremities, and may be housed in a device optimized for attaining reproducible blood flow to the region of the subject that is measured, and for minimizing the effects of the housing pulling, stretching, pressing, compressing the subject's skin. A pressure sensor may be used to ensure that measurements are taken at an optimal pressure. A touch sensor may be used to activate a system and/or to ensure flushness. In addition, the spectroscopic measurement may be coupled with a temperature measurement means that detects the subject's local body temperature in or near the region being measured, or the subject's core or mean body temperature, or the ambient temperature proximate to the probe, or any combination of those measurements. The system may also include one or more indicators to communicate information to a test subject.01-15-2009
20110282167SYSTEM FOR NONINVASIVE DETERMINATION OF ALCOHOL IN TISSUE - An apparatus and method for non-invasive determination of attributes of human tissue by quantitative infrared spectroscopy to clinically relevant levels of precision and accuracy. The system includes subsystems optimized to contend with the complexities of the tissue spectrum, high signal- to-noise ratio and photometric accuracy requirements, tissue sampling errors, calibration maintenance problems, and calibration transfer problems. The subsystems include an illumination/modulation subsystem, a tissue sampling subsystem, a calibration maintenance subsystem, an FTIR spectrometer subsystem, a data acquisition subsystem, and a computing subsystem.11-17-2011
20120289799High-Throughput Alignment-Insensitive Optical Connector for Laser-Based Photoplethysmography - One embodiment of an optical coupling for use in a photoplethysmographic device having a first light guide (11-15-2012
20120289798Anti-Reflective Launch Optics in Laser-Based Photoplethysmography - An embodiment of a light launching portion of a photoplethysmographic device having a laser (11-15-2012
20130018239DEVICES AND METHODS FOR REDUCING WIRELESS COMMUNICATION IN A PATIENT MONITORING SYSTEMAANM Lisogurski; DanielAACI BoulderAAST COAACO USAAGP Lisogurski; Daniel Boulder CO US - The present disclosure relates generally to patient monitoring systems and, more particularly, to wireless patient sensors and patient monitors. In an embodiment, a patient sensor device includes an emitter configured to emit light into a tissue of a patient as well as a detector configured to detect the light from the tissue of the patient and produce a corresponding electrical signal. The patient sensor also includes signal processing circuitry configured to receive and convert the electrical signal of the detector into detector signal data. The patient sensor also includes a wireless module communicatively coupled to a patient monitor and configured to transmit a physiological parameter value, the detector signal data, or both, to the patient monitor. The patient sensor also includes a processor configured to determine whether the patient sensor or the patient monitor should calculate the physiological parameter value based, at least in part, on the detector signal data. The processor is also configured to calculate the physiological parameter value for the patient based, at least in part, on the detector signal data, if the processor determines that the patient sensor should calculate the physiological parameter value. The processor is also configured to send the detector signal data to the patient monitor, via the wireless module, to calculate the physiological parameter value for the patient based, at least in part, on the detector signal data, if the processor determines that the patient monitor should calculate the physiological parameter value.01-17-2013
20130172701MULTIPLE WAVELENGTH SENSOR EMITTERS - A physiological sensor has light emitting sources, each activated by addressing at least one row and at least one column of an electrical grid. The light emitting sources are capable of transmitting light of multiple wavelengths and a detector is responsive to the transmitted light after attenuation by body tissue.07-04-2013
20130144138MEASURING DEVICE FOR GATHERING SIGNALS MEASURED IN VITAL TISSUE - The invention relates to a measuring device comprising a light source device (Q06-06-2013
20130144139METHOD AND DEVICE FOR DETERMINING A BLOOD CONSTITUENT - A method and device for determining the concentration of blood constituents, in particular haemoglobin, in a hose line of an extracorporeal blood circuit of an extracorporeal blood treatment apparatus, and an extracorporeal blood treatment apparatus with a device for determining the concentration of a blood constituent, are based on the correction of the influence of the blood flow rate of the blood flowing through the hose line on the determination of the concentration of the blood constituent. The device comprises a computing and evaluation unit configured such that a correction factor is ascertained for the influence of the blood flow rate on the determination of the concentration of the blood constituent. The concentration of the blood constituent is then determined based on a relationship describing the dependence of the concentration of the blood constituent on the intensity of the decoupled electromagnetic radiation, taking account of the correction factor.06-06-2013
20080200784Method and device for measuring parameters of cardiac function - A device for non-invasively measuring parameters of a cardiac blood vessel in a patient is provided. The device comprises at least one light source that emits light in the 400 nm to 1000 nm wavelength range and at least one photodetector adapted to receive light emitted by the light source, which light is reflected from or transmitted through tissue of the patient, the output of said photodetector correlating with a parameter of the blood vessel. The device also includes a probe which permits delivery of light from the light source to an external tissue site on the patient in the proximity of a cardiac blood vessel and permits the photodetector to receive light originating from the light source which has been reflected from or transmitted through tissue at the patient site.08-21-2008
20110230740METHOD AND APPARATUS FOR DETERMINING THE HEMATOCRIT OF A BLOOD SAMPLE UTILIZING THE INTRINSIC PIGMENTATION OF HEMOGLOBIN CONTAINED WITHIN THE RED BLOOD CELLS - A method for determining the hematocrit of a blood sample is provided that includes the steps of: 1) depositing the sample into an analysis chamber adapted to quiescently hold the sample for analysis, the chamber defined by the interior surfaces of first and second panels and a height extending there between, wherein both panels are transparent, and the height is such that at least some of the red blood cells within the sample contact both interior surfaces of the panels and one or more lacunae within the quiescent sample extend between the interior surfaces; 2) imaging at least a portion of the quiescent sample, which sample portion contains the red blood cells and one or more lacunae to determine an optical density of the imaged portion of the sample on a per image unit basis; 3) selecting and averaging the optical density values of the image units aligned with the red blood cells contacting the interior surfaces, and assigning an upper boundary value of 100% to the average optical density value of those image units; 4) selecting the optical density values of the image units aligned with the one or more lacunae, and assigning a lower boundary value of 0% to the optical density values of those image units; and 5) determining the hematocrit of the sample by assigning relative values to the optical density value of each image of the imaged sample portion as a function of the upper and lower boundary values, and averaging the relative values.09-22-2011
20120283532BIOLOGICAL OPTICAL MEASUREMENT INSTRUMENT AND METHOD FOR DISPLAYING INFORMATION RELATING TO NECESSITY/UNNECESSITY OF REPLACEMENT OF LIGHT-EMITTING UNIT - Disclosed is a biological optical measurement instrument provided with: a light source unit which has a light-emitting unit that emits light and irradiates the light to an object; a light measurement unit configured to measure passing light at a measurement point of the object: a signal processing unit configured to process hemoglobin information outputted from the light measurement unit and create a light measurement image; and a display unit configured to display the light measurement image, further provided with a measurement/determination unit configured to measure the deterioration state of the light-emitting unit from the light output of the light-emitting unit and an electric current injected into the light-emitting unit and determine the necessity/unnecessity of replacement of the light-emitting unit, wherein the display unit displays information relating to the necessity/unnecessity of replacing the light-emitting unit determined by the measurement/determination unit.11-08-2012
20120029329ANALYTE DETECTION SYSTEMS AND METHODS USING MULTIPLE MEASUREMENTS - In certain embodiments, a sampling assembly is for use with a main analyzer. The main analyzer is configured to sense an analyte in a body fluid obtained from a patient through a first fluid passageway extending from the main analyzer. The sampling assembly includes an instrument portion separate from the main analyzer and including at least one sensor. The instrument portion is removably engaged with the first fluid passageway. The at least one sensor is in sensing engagement with the first fluid passageway such that the at least one sensor can sense a property of a fluid within the first fluid passageway.02-02-2012
20130204102SYSTEM AND METHOD FOR NON-INVASIVE DETERMINATION OF HEMOGLOBIN CONCENTRATION IN BLOOD - A system and method for measurement of absolute value of hemoglobin concentration non-invasively is provided. The system comprises a probe device comprising a sliding top structurally configured to be manually slid forward and backward onto the finger seat which is positioned on top of the housing for placing a fingertip. The finger seat houses two cavities for housing a set of three light emitting diodes and a photodetector respectively. Multiple distinct wavelengths of light transmitted through the fingertip is detected by the photodetector. Further, electronic signals generated by the photodetector are processed to obtain alternating and direct components of light corresponding to each wavelength. A system of three equations are obtained including unknown values of two primary constituent absorbers and known consolidated values of one or more secondary constituent absorbers corresponding to each wavelength of light. The system of equations are then solved simultaneously derive absolute value of hemoglobin concentration.08-08-2013

Patent applications in class Determining blood constituent

Patent applications in all subclasses Determining blood constituent