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Measuring or detecting nonradioactive constituent of body liquid by means placed against or in body throughout test

Subclass of:

600 - Surgery

600300000 - DIAGNOSTIC TESTING

Patent class list (only not empty are listed)

Deeper subclasses:

Class / Patent application numberDescriptionNumber of patent applications / Date published
600310000 Infrared, visible light, or ultraviolet radiation directed on or through body or constituent released therefrom 1074
600345000 Electroanalysis 462
600365000 Glucose measurement 451
600364000 Blood gas 41
600367000 Holder for color indicator (e.g., fertility tester) 5
20130060114TEST ELEMENT FOR ANALYZING A BODY FLUID - A test element comprises a puncture element and a test pane. The puncture element has a tip for generating a wound and a capillary structure. The capillary structure extends from the tip to the test panel and has a fluid connection to the tip configured to allow body fluid to penetrate into the capillary structure. The test panel contains at least a part of the reagent system and is positioned in the test element adjacent to a part of the capillary structure of the puncture element in such a manner that body fluid penetrating into the capillary structure contacts a liquid entry side of the test panel. The test panel comprises a transparent support layer and a test layer applied to the support layer by coating, the side of the test panel facing away from the support layer forming its liquid entry side, which faces toward the capillary structure.03-07-2013
20110077495Detection indicator - An apparatus comprises a detection indicator and a housing. The detection indicator is configured to change from a first visual indication to a second visual indication upon contact with a fluid based on a characteristic of the fluid. The housing comprises an interior chamber configured to receive the fluid and to provide contact between the fluid and the detection indicator. The housing is configured to removably engage a lumen inserted into a patient to receive the fluid from the patient through the lumen.03-31-2011
20120316415FLUID CHARACTERISTIC MEASUREMENT - An apparatus comprises a detection indicator, a housing, and an exoskeleton in which the housing nests. The detection indicator is configured to furnish a visual indication upon contact with a fluid responsive to a characteristic of the fluid. The housing comprises an interior chamber configured to receive the fluid and to provide contact between the fluid and the detection indicator. The housing is configured to removably engage a conduit coupled to a source of a fluid sample, which may be a lumen inserted into a patient to receive fluid therefrom. In methods for use with the apparatus, a sample is collected, a characteristic is measured by the apparatus, and the apparatus is disconnected so as to avoid leakage of the sample and exposure of personnel.12-13-2012
20130131479DIAGNOSTIC SYSTEM - A composite diagnostic system comprising a support member having a membrane penetration element; a bodily fluid collection point positioned for collection of a bodily fluid released by application of the membrane penetration element to a user's body; a test material positioned in the support member such that in use the bodily fluid is brought into contact with the test material.05-23-2013
20130131480BODY FLUID TESTING DEVICE - Body fluid testing device for analyzing a body fluid comprises a test media tape adapted to collect the body fluid. The test media tape comprises a tape and test media portions. A free tape portion without test medium is located between successive test media portions. The testing device further comprises a supply portion. The supply portion comprises a housing in which uncontaminated test media tape is contained. The housing further has an opening for withdrawing test media tape from the housing. The testing device further has a sealing means for closing the opening against the surrounding. A free tape portion of the test media tape is located between a wall of the housing and the sealing means when the sealing means closes the opening. Further aspects concern a test media cassette with sealing means and a method for providing test media while holding them sealed against humidity during onboard storage.05-23-2013
600363000 Perfusion detection 5
20130030272TONOMETRIC DEVICE FOR EXAMINING RESPIRATORY INSUFFICIENCY AND REGIONAL TISSUE PERFUSION FAILURE - A probe comprising a tubular member arranged substantially in a plane within a perimeter fitting into the sublingual or postlabial area of a human patient. The tubular member is made preferably of silicone rubber or a material permeable for gases, particularly for carbon dioxide, and forming a barrier against body fluids. The tubular member has consecutive curved sections communicating with each other and form a continuous flow pass. Ends of the tubular member have connection tubes adapted for delivering the fluid inside the lumen of the tubular member directly or indirectly to a measuring apparatus. The connection tubes are made preferably of a material substantially impermeable for carbon dioxide.01-31-2013
20090326356CARDIAC SIGNAL SENSOR CONTROL - An optical perfusion sensor may monitor blood oxygen saturation of blood-perfused tissue, which may be referred to as tissue perfusion, until a tissue perfusion value is within a threshold range of a reference value, and, in some examples, for at least a minimum period of time. The tissue perfusion value may indicate an absolute blood oxygen saturation level or a relative change in blood oxygen saturation level. The reference value may be, for example, determined by an optical oxygenation (O2) variation index that indicates a change in blood oxygen saturation of tissue. In some examples, an operation of a cardiac signal sensing module may be controlled based upon detecting a threshold change in tissue perfusion. For example, the cardiac signal sensing module may be activated upon detecting a threshold change in tissue perfusion.12-31-2009
20100049023Non-invasive method and system for determining physiological characteristics - A non-invasive method of determining a physiological characteristic, comprising providing at least one physiological sensor that is adapted to measure at least one physiological characteristic at a target measurement site on a subject's body, heating an extended tissue region on the subject's body, whereby blood perfusion of the tissue region is enhanced, and measuring at least one physiological characteristic with the physiological sensor during or within a predetermined period after heating the extended tissue region.02-25-2010
20080294027System for extracting morphological information through a perfusion assessment process - A perfusion assessment system is proposed. The system includes means for providing an echo-power signal indicative of a reperfusion of a contrast agent in a body-part of a living subject following destruction of a significant portion of the contrast agent in the body-part, means for associating the echo-power signal to a perfusion function with an S-shape based on a plurality of elementary perfusion functions with said S-shape each one for a corresponding value of at least one perfusion parameter, the elementary perfusion functions being weighted according to a probability density distribution of the at least one perfusion parameter, wherein the S-shape includes an initial portion with substantially zero first derivatives, a final portion with substantially zero first derivatives, and a central portion between the initial portion and the final portion changing monotonically from a value of the initial portion to a value of the final portion, means for determining at least one shape indicator of the probability density distribution, and means for comparing the at least one shape indicator with at least one predetermined further shape indicator to identify morphological characteristics of the body-part according to a result of the comparison.11-27-2008
20080221421APPARATUS FOR MEASURING PERFUSION RATE OF LEGS - The present invention relates to an apparatus for measuring the perfusion rate of legs. The measurement apparatus of the present invention includes a light leakage prevention unit including a light emitting device for radiating light having a certain wavelength onto a living body injected with Indocyanine Green (ICG), and a light leakage prevention housing formed to prevent transmission of external light. A data acquisition unit includes a band pass filter for passing therethrough only light, having a near infrared wavelength, in a fluorescence image emitted by the ICG and the light emitting device, and a Charge Coupled Device (CCD) camera for photographing a near infrared wavelength region. A data processing unit calculates a perfusion rate of the living body on a basis of data about the near infrared wavelength region through a data cable connected to the data acquisition unit. A data output unit outputs the perfusion rate calculated by the data processing unit.09-11-2008
600366000 Equilibration and analysis of fluid 4
20090043184CATHETER AND PROBE FOR MEASURING ANALYTES OR OTHER PARAMETERS - A medical sensing system including an access tube with a fluid infusate lumen and a sensing probe that can be passed through a second lumen in the access tube and extended into the vasculature for sensing a blood parameter. The sensing probe has a sensor on a distal end thereof and a shape that permits it to extend from the access tube such that the sensor is displaced laterally from the access tube, and out of the infusate flow. If the sensing probe passes through the lumen opening at the distal tip of the catheter, the distal end of the probe bends or otherwise deflects laterally so that the sensor is displaced laterally from the infusate flow path. Alternatively, the probe may exit a side port of the access tube upstream of an infusate side port. The deflectable probe is particularly useful for sensing glucose in blood through any number of conventional, off-the-shelf catheters.02-12-2009
20090312622Device And Method For Determining A Value Of A Physiological Parameter Of A Body Fluid - A device for determining a value of a physiological parameter of a body fluid of a body under investigation, the device comprising a fluid reservoir for containing a perfusate fluid, a body interface insertable into the body under investigation for a fluid communication between the fluid reservoir and the body fluid, a fluid conduit between the fluid reservoir and the body interface, a bidirectional fluid transport unit for transporting the perfusate fluid from the fluid reservoir through the fluid conduit a the body interface into the body under investigation and for subsequently transporting a mixture of the perfusate fluid and the body fluid from the body under investigation through the body interface into the fluid conduit, and a sensor for sensing the value of the physiological parameter based on an analysis of the mixture of the perfusate fluid and the body fluid.12-17-2009
20130165758MINIATURE INFUSION PUMP - A miniature infusion pump (MIP) suitable for use with a human patient is configured for non-human animal testing. In one example, a MIP includes an electromagnetic piston pump, a circuit board, and a housing. The pump is configured to deliver a therapeutic agent from a reservoir through an implantable catheter. The circuit board includes programmable electronics configured to control the pump to deliver the therapeutic agent through the catheter. The pump and the circuit board are sealed within the housing. The MIP is sized to be at least one of harnessed to or implanted in a non-human test subject including a weight greater than or equal to approximately 150 to approximately 250 grams.06-27-2013
20120203089MONITORING SYSTEMS AND METHODS WITH FAST INITIALIZATION - Some embodiments provide a system for synchronizing and configuring monitoring devices. In some embodiments, a patient monitoring device settings module is configured to automatically provide configuration settings to a plurality of patient monitoring devices. A monitoring device data module is configured to receive measurement data from at least one of the patient monitoring devices. An electronic medical records system interface is configured to provide patient data at least partially derived from the received measurement data to an electronic medical records system. A patient records interface is configured to provide patient data to at least one of the patient monitoring devices.08-09-2012
600362000 Absorbent patch for fluid analysis 4
20110166433Systems, Methods, and Devices for Sampling Bodily Fluid - A fluid sampling system is disclosed comprising a fluid drawing device and a fluid sampling device. In one embodiment, the fluid sampling device has a base portion having a cannula, a handle, and a ridge extending around at least a portion of an outer surface. A top portion has a flange adapted to engage the ridge to couple the top portion to the base portion. In another embodiment, the fluid sampling device has a base portion having a cannula, a handle, a mounting portion, and a test strip coupled to the base portion at least partially within the mounting portion. In yet another embodiment, the fluid sampling device has a test strip housing for receiving an end of a test strip therein. Extending from an end of the test strip housing is a blunt cannula.07-07-2011
20110166432DIAGNOSTIC INTERLABIAL PAD - A diagnostic agent is delivered intravaginally or to the interlabial space by positioning an interlabial device, such as an absorbent pad, between the labia. The pad is retained between the labia to deliver an active agent, or allow a reaction with a diagnostic agent. Alternatively, the pad is applied after the diagnostic agent is administered, to help reduce discomfort to the subject, or loss of the diagnostic agent. The active agent may be carried by the pad itself, or in an intravaginal extension of the pad, or separately in a suppository or other dosage form. In particular examples, the pad has a smaller minor portion superimposed on a larger major portion, and the smaller minor portion is inserted as a leading edge between the labia of the subject to facilitate interlabial insertion. In another example, the pad is placed interlabially after insertion of an agent.07-07-2011
20130197334BIODETECTOR - The invention concerns a Biodetector with a functionalised surface for isolating molecules or cells from the human body. In order to improve a Biodetector of the type mentioned above such that the functionalised surface of the Biodetector or there upon enriched molecules or cells are exposed to a lower abrasion, and the biocompatibility of the Biodetector is improved, the Biodetector is designed to remove a fluid from the human body and absorb it into an inner space of the Biodetector, wherein the functionalised surface is oriented to the inner space of the Biodetector.08-01-2013
20120095308DETECTOR AND DETECTION METHOD - Provided is a strip-shaped detector that detects an analyte in a liquid sample. The detector includes a collecting member that directly collects a liquid sample from a living organism, a holding member that holds a labeling reagent binding specifically to the analyte in a state where the labeling reagent can move along with the movement of the liquid sample, a detecting member to which a detection reagent is immobilized which captures a complex of the analyte and the labeling reagent by binding specifically to the analyte, an absorbing member that can absorb the liquid sample, and a liquid-impermeable supporting member, wherein the respective members are arranged on the supporting member in the longitudinal direction of the detector so that the liquid sample moves through the inside of these members, and the collecting member includes a protruding portion sticking out of the supporting member at the upstream side in the movement direction of the liquid sample.04-19-2012
Entries
DocumentTitleDate
20130030262SENSING FOLEY CATHETER - Foley type catheter embodiments for sensing physiologic data from a urinary tract of a patient are disclosed. The system includes the catheter and a data processing apparatus and methods for sensing physiologic data from the urinary tract. Embodiments may also include a pressure sensor having a pressure interface at a distal end of the catheter, a pressure transducer at a proximal end, and a fluid column disposed between the pressure interface and transducer. When the distal end is residing in the bladder, the pressure transducer can transduce pressure impinging on it into a chronological pressure profile, which can be processed by the data processing apparatus into one or more distinct physiologic pressure profiles, for example, peritoneal pressure, respiratory rate, and cardiac rate. At a sufficiently high data-sampling rate, these physiologic data may further include relative pulmonary tidal volume, cardiac output, relative cardiac output, and absolute cardiac stroke volume.01-31-2013
20130030263Device for Taking a Sample of a Body Fluid and Method for Implementing Same - The invention relates to a device (01-31-2013
20110190604Nitric oxide sensors and systems - The present disclosure relates to nitric oxide sensors and systems.08-04-2011
20100152557APPARATUS FOR MEASURING BIOLOGICAL INFORMATION AND EARPHONE HAVING THE SAME - Disclosed is an apparatus for measuring biological information and an earphone having the same for contacting with a uniform pressure a user body part using an elastic member. The apparatus includes a first housing; a second housing foldably connected with the first housing; a third housing foldably connected with the second housing and provided with a sensor for measuring the biological information; a plurality of joint parts for connecting the housings to be folded or unfolded to each other; one or more locking parts for restraining or releasing the housings to be folded or unfolded to each other; and the elastic member for applying the same pressure to make the sensor contact with the user's body by enabling the respective housings to be folded or unfolded using a stress-strain.06-17-2010
20100152555METHOD AND DEVICE FOR MICRODIALYSIS SAMPLING - The microdialysis technique and device of the present invention can be used to study metabolic aspects of human and animal organs. When a microdialysis catheter is for example placed into the substance of a beating heart, there is always concern for problems with the catheter position. Further, there is always a risk for damage to heart tissue as well as to the catheter. The present invention is designed to avoid such damages, and a study has confirmed that data obtained from the epicardial probe of the present invention reflects the state of the myocardial metabolism. In anesthetized normoventilated pigs (n=20), a sternotomy was performed and a Gore-tex suture snare was placed around a branch of the left anterior descending (LAD) artery. One microdialysis probe was inserted in the myocardial tissue supplied by the snared LAD branch. Another microdialysis probe was placed on the epicardial surface above the myocardial probe. The protocol included four, ten minute ischemic periods (intervention group) followed by a forty minute ischemic period. The control group was only exposed to a forty minute ischemic period. It was possible to place the microdialysis probes of the present invention on the epicardial surface, and to recover samples reflecting the myocardial metabolic state of the heart. It was also possible to measure rapid changes in concentrations especially for lactate, where ischemia periods as short as ten minutes resulted in detectable increases. A similar pattern was found when analysing glucose and glycerol concentrations in paired samples. Data obtained from the device and method of the present invention, placed on the epicardial surface showed a similar pattern compared to data from a standard probe placed in the myocardium. Thus, the epicedial application of the present invention is useful for perioperative monitoring during cardiac surgery.06-17-2010
20100152554MONITORING DEVICE - Provided is a small sized, portable monitoring device capable of determining an analyte under investigation and having a system and method for providing compliance information to a user of his management of a disease, and for easily navigating a menu structure by means of manual control(s). Further provided is the provision of feedback to the user in form of a disease management information to be easily understood by a user such as the further described COMPLIANCE WINDOW or the INDICATOR CATEGORIES. The user interface can be used in connection with a glucose diagnostic device, a coagulation diagnostic device, immunoassay diagnostic device, and other monitoring devices such as an blood pressure monitor or a pedometer.06-17-2010
20110196214Fetal Scalp Blood Analyzer - A hand-held analyzer for collecting a sample of blood from the scalp of a fetus and measuring the pH or other blood characteristic of the blood sample. The analyzer includes a probe with a proximal end and a gasket that facilitate a firm and positive placement of the probe against the scalp. The probe includes a capillary tube for collecting blood and an extensible lancet which at rest is positioned within the capillary tube. During operation, the lancet is extended to make an incision in the scalp. The lancet then retreats, and blood flows into the capillary tube. Sensors for measuring pH are in liquid communication with the capillary tube. A display on or near the hand-held analyzer shows a readout of the fetal scalp blood pH or other blood characteristic. Measuring the pH of the fetal scalp blood in utero can provide early detection of acidosis and likely hypoxia.08-11-2011
20100049014Sensor Inserter Assembly - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion.02-25-2010
20100076280Health Monitor - Methods and devices to detect analyte in body fluid are provided. Embodiments include enhanced analyte monitoring devices and systems.03-25-2010
20130079603INTRAGASTRIC IMPLANT DEVICES - An intragastric anchor implant device with an elongate member having proximal and distal ends with atraumatic features disposed thereon is described herein. The atraumatic features inhibit damage to the tissues of the stomach and the gastrointestinal tract and help anchor the device. The elongate member may be substantially rigid to resist bending and engage a tissue of the stomach or gastrointestinal tract to prevent passage therethrough and may include one or more bends to conform to the shape of the tract. The anchor implant device may be coupled with a therapeutic device, such as an intestinal bypass sleeve with a sliding seal, such as an expandable structure, that secures the sleeve to direct a flow of food particles from the stomach therethrough, for use in treating various disorders, including obesity and diabetes. Methods of deploying the anchor implant devices are also disclosed.03-28-2013
20130079604SYSTEMS AND METHODS FOR PARENTERALLY PROCURING BODILY-FLUID SAMPLES WITH REDUCED CONTAMINATION - The present invention is directed to the parenteral procurement of bodily-fluid samples. The present invention is also directed to systems and methods for parenterally procuring bodily-fluid samples with reduced contamination from dermally-residing microbes. In some embodiments, a bodily-fluid withdrawing system is used to withdraw bodily fluid from a patient for incubation in culture media in one or more sample vessels. Prior to withdrawing bodily fluid into the one or more sample vessels for incubation, an initial volume of withdrawn bodily fluid is placed in one or more pre-sample reservoirs and is not used for the incubation in culture media.03-28-2013
20130035564REAL TIME INTRAVASCULAR MONITORING DEVICE - A real time tissue sampling and analysis system includes a catheter including an elongated body defining at least one internal lumen, a sampling device positionable within the at least one internal lumen of the catheter for collecting a tissue sample, and a biochip disposed within the at least one internal lumen. The biochip includes a substrate for receiving the tissue sample, a marker for interacting with the tissue sample, and a sensor for identifying a characteristic of the tissue sample and transmitting data about the tissue sample to a processing unit for analysis.02-07-2013
20130035566Method and Apparatus for Enhancement of Transdermal Transport - According to the present invention, a method for enhancing transdermal transport is disclosed. The method includes the steps of increasing a permeability an area of a membrane with a permeabilizing device. The membrane may be, inter alia, biologic skin or synthetic skin. The permeabilizing device may be an ultrasound-producing device. A substance is transported into and through the area the membrane. The substance may be a drug, a vaccine, or a component of interstitial fluid.02-07-2013
20130035565Method and System for the Reactivation of an Implantable Chemical Sensor - A method for the operation and, in particular, for the reactivation of an implantable chemical sensor that measures values in bodily fluid, including the steps of wetting the sensor surface with a reactivation substance that carries out a chemical reaction on the sensor surface that removes molecules originating in the bodily fluid, or the reaction or degradation products thereof, which have collected on the sensor; and dewetting the sensor surface of the reactivation substance, wherein the sensor surface is wetted and dewetted with the reactivation substance in situ.02-07-2013
20090024009Body fluid sampling device with a capacitive sensor - A body fluid sensing device with a body fluid capture structure and a body fluid measurement sensor positioned in the body fluid capture structure. A capacitance sensor is coupled to the body fluid measurement sensor. The capacitance sensor is used to assist in the positioning of a body part relative to the body fluid capture structure.01-22-2009
20130041236SAMPLE ANALYSIS SYSTEM AND METHOD OF USE - A sample collection device having a sample container and microfluidic device having one or more microfluidic circuits, the system for analyzing biological samples. The microfluidic device has a sample inlet port, a microconduit in communication with the inlet port and with reaction chamber. The reaction chamber is connected to an air vent via another microconduit. Air may be vented from the microfluidic circuit via the air vent of the microfluidic circuit via an air vent in the sample container.02-14-2013
20130123589WEARABLE DEVICE, BIOLOGICAL GAS MEASUREMENT DEVICE AND METHOD - One aspect of the present invention relates to a wearable device worn in contact with a user's skin including a gas reservoir structure configured to, when the user wears the wearable device, form a space for accumulating a biological gas component released from a skin surface or expiration of the user and a gas sensor device configured to measure the biological gas component accumulated in the formed space.05-16-2013
20090156911LOW DRAW VOLUME ANALYTE DETECTION SYSTEMS - Systems and methods for determining the concentration of an analyte in a sample such as bodily fluid are disclosed. Systems and methods disclosed herein comprise reducing the volume of sample withdrawn from the source of biological fluid. Low draw volume systems can be implemented using small inner diameter tube, valves and one or more sensors, for example. A method for calibrating a measurement of an analyte in a fluid sample for dilution of the fluid sample is also disclosed.06-18-2009
20100094105PIEZOELECTRIC TRANSDUCER - A miniature piezoelectric transducer element is provided, comprising; (a) a cell element having a cavity; (b) a flexible piezoelectric layer attached to the cell member, the piezoelectric layer having an external surface and an internal surface, the piezoelectric layer featuring such dimensions so as to enable fluctuations thereof at its resonance frequency upon impinging of an external acoustic wave; and (c) a first electrode attached to the external surface and a second electrode attached to the internal surface of the piezoelectric layer. At least one of the electrodes may be specifically shaped so as to provide a maximal electrical output, wherein the electrical output may be current, voltage or power. A preferred shape of the electrodes includes two cores interconnected by a connecting member. The transducer element may function as a transmitter.04-15-2010
20130090535SYSTEMS, DEVICES, AND METHODS INCLUDING PARAMAGNETIC OSCILLATION, ROTATION, AND TRANSLATION OF HEMOZOIN ASYMMETRIC NANOPARTICLES IN RESPONSE TO DARK-FIELD OR RHEINBERG DETECTION OF THE PRESENCE OF HEMOZOIN - Systems, devices, and methods are described for providing a monitor/treatment device configured to, for example, detect hemozoin, as well as to monitor or treat a malarial infection.04-11-2013
20110066012NEEDLE INSERTION SYSTEMS AND METHODS - A housing may have a needle, plunger, and bias mechanism supported within the housing by a tab configured to retain the plunger in position and to allow the plunger to move under bias force imparted by the bias mechanism to move the needle to an insert position when the tab is removed. A base and a structure may be configured for relative movement there between and may be adapted to be secured to a user with a cannula extending through a body of the structure into the user during use of a medical device. A housing may be adapted to be secured to a user to support a medical device operable with an insertion needle, the housing having a magnifying material for increasing visibility of an injection site.03-17-2011
20090240121Intravascular sensor and insertion set combination - An intravascular sensor assembly insertable into an intravenous catheter, the sensor assembly includes a sheath having a sheath proximal end and a sheath distal end wherein an outer diameter of the sheath is sized to be substantially equal to the outer diameter of an insertion needle of the intravenous catheter, a hub sealingly connected to the sheath proximal end, the hub adapted for removably coupling to the intravenous catheter, a sensor disposed within the sheath, the sensor having a sensor shank with a shank distal end and a shank proximal end, a plurality of sensor elements including a working electrode with a reagent matrix disposed thereon, the reagent matrix comprising an enzyme capable of catalyzing a reaction involving a substrate for the enzyme and a reference electrode, the plurality of sensor elements disposed adjacent the shank distal end, a plurality of connector pads disposed at the shank proximal end where the plurality of connector pads are contained within the hub and the plurality of sensor elements are exposed adjacent the sheath distal end, and a plurality of elongated conductive elements where each of the plurality of conductive elements electrically couples one of the plurality of sensor elements to one of the plurality of connector pads, and a cable electrically coupled to the plurality of connector pads.09-24-2009
20090270697ANALYTE METER PROTECTORS AND METHODS - Analyte meter protectors, meters that include the same, and methods.10-29-2009
20090270696ANALYTE METER PROTECTORS AND METHODS - Analyte meter protectors, meters that include the same, and methods.10-29-2009
20130066171Lancet Magazine and Method for the Production Thereof - A lancet magazine is disclosed which includes a housing and a plurality of lancets each of which is enclosed in a sterile chamber of the housing, wherein the chambers each have a puncturing opening which is closed with a foil, wherein the lancets include a sample receiving device for receiving body fluid and the chambers each include a further opening which is closed with a membrane that is permeable to gas and fluid and includes a lower side that faces the lancet and serves to receive body fluid from the sample receiving device and an upper side that serves to transfer body fluid to a test field arranged on the membrane.03-14-2013
20100121162CHILD-FRIENDLY ANALYTE MEASUREMENT INSTRUMENT - Embodiments of a child-friendly analyte measurement system are provided for detecting at least one analyte in a bodily fluid. A measurement system comprises at least one measurement instrument for detecting the analyte in the bodily fluid, such as a commercially available measurement instrument. The measurement instrument is configured as a portable hand-held instrument and has a housing with at least one display element. Furthermore, the measurement system comprises a toy, in particular a figurine or a toy animal. The toy has at least one receptacle for reversibly holding the measurement instrument, which receptacle is configured such that if the measurement instrument is held by the receptacle, the display element is accessible, at least in part. The measurement instrument is configured such that it can be used both in the measurement system and also, optionally, independently of the toy. Further aspects include a kit, a method, and the toy for the provided measurement system.05-13-2010
20110046457MULTILUMEN CATHETER - A multilumen catheter having tubings extending into lumens within the catheter. The lumens may be used for blood, drugs or other medicants. The lumens may also be used for sensors. The junction element, external to the patient, connects the tubings to the lumens. The tubings, also external to the patient, connect to infusion members, to which one or more infusion systems may be connected to deliver blood, drugs and other medicants to the patient. A sensor having a sensing element may extend through the sensor lumen and be positioned internal to the patient for physiological parameter sensing. An external portion of the sensor may be connected to associated electronics to provide automatic monitoring of the physiological parameters and automatic delivery and control of the infusants. Also, a central line catheter for delivering fluids directly into a main artery or vein near the heart, which contains a first lumen to deliver a fluid through the central line catheter and a second lumen containing a sensor capable indicating a characteristic level in blood. The first lumen delivers the fluid downstream of the sensor to prevent any interference between the fluid delivery and the sensor readings. In other versions, the central line catheter can have additional lumens for additional purposes. In addition, the central line catheter can further include a flush sleeve to remove debris around the sensor.02-24-2011
20110046455METHODS AND DEVICES FOR EXAMINING A PARTICULAR TISSUE VOLUME IN A BODY, AND A METHOD AND A DEVICE FOR SEGMENTING THE PARTICULAR TISSUE VOLUME - A tip of an elongate device is navigated into a particular tissue volume in order to examine the particular tissue volume in a body and part of the tissue volume is analyzed in real-time by way of a biosensor. In at least one embodiment, in the process, either the biosensor can be arranged on the tip of the device or the device includes a catheter, by which a substance to be analyzed is transported out of the tissue volume from the tip to the biosensor arranged at the proximal end of the catheter.02-24-2011
20120116190Continuous Analysis Device And Sample Component Control System - A continuous analysis apparatus capable of transmitting information about components in body fluid to another apparatus such as medicine dosing apparatus more correctly without giving a user displeasure. The continuous analysis apparatus according to the present invention includes a sensing unit 05-10-2012
20100081896GASTRIC INSERTION CONFIRMATION DEVICE AND METHOD OF USE - A confirmation device. The device includes a housing having a central passageway and a secondary passageway extending from the central passageway. The device also has a negative pressure member in communication with the secondary passageway and an indicator mechanism in fluid communication with the secondary passageway for visually indicating the presence of one or more components within the secondary passageway. The negative pressure member is operable to draw fluid across the indicator mechanism.04-01-2010
20100081895WIRELESS MEDICAL TELEMETRY SYSTEM AND METHODS USING RADIO FREQUENCY ENERGIZED BIOSENSORS - A system is provided that furnishes physiological or biomechanical parameters from sensors placed upon or within a subject. The system comprises radio frequency energized biosensor (RFEB) devices that are powered by and communicate with an external receiver and monitoring apparatus. One embodiment of the system provides for infant monitoring in a crib utilizing RFEB devices incorporated into a dermal patch. Said patch communicates with a receiver suspended above the crib and alerts of early warning signs of sudden infant death syndrome (SIDS) or other physiologic abnormalities. Another embodiment comprises implantable RFEB devices that relay information related to the condition of an internal tissue, organ, or cavity to an external receiver, monitor, and recorder. Other embodiments include wearable sensors for detecting a subject attempting to get out of bed, dislodge medical equipment, or stray from a given location.04-01-2010
20090012377METHOD AND STRUCTURE FOR SECURING A MONITORING DEVICE ELEMENT - Structures and methods for attaching a device to a user's skin are provided. Embodiments include refreshing an adhesive attaching an element of an analyte monitoring device so that a first adhesive attaches the element of the analyte monitoring device during a first time period and a second adhesive attaches the element of the analyte monitoring device to the user's skin during a second time period. A sensor remains at least partially inserted into the user's while the refreshing of the adhesive from the first to the second adhesive occurs.01-08-2009
20100087716Portable microchip module for instantaneous analysis of bodily fluids - A portable microchip substrate supported in a receptacle having one end connected to a catheter inserted in the body of a patient. The other end of the receptacle is connected to a needleless syringe for drawing a bodily fluid sample (e.g. blood) through the receptacle and into contact with the substrate. The substrate is adapted to instantaneously perform diagnostic tests on the fluid sample in contact therewith within the receptacle. A communication device on the receptacle transmits signals to an analyzer which includes a display for indicating various diagnostic characteristics of the bodily fluid sample in real time. The receptacle and the substrate may be cleaned (sterilized) for re-use or may be disposed of after a one-time use. In an alternatively preferred embodiment, the substrate and/or communication device are directly carried on and supported by the insertable catheter.04-08-2010
20120238836System, devices, and methods for real-time monitoring of cerebrospinal fluid for markers of progressive conditions - Systems, devices, methods, and compositions are described for providing real-time monitoring of cerebrospinal fluid for markers of progressive conditions.09-20-2012
20080294025Anti-Inflammatory Signal Molecules and Exercise - The present invention provides methods for assessing the effect of exercise on an individual by measuring changes in the concentration of a compound in the individual's blood. Specifically, the invention measures changes in the concentration of an anti-inflammatory signal molecule or endogenous morphine. Anti-inflammatory signal molecules include, for example, adrenocorticotropin (ACTH), cortisol, and interleukin-10 (IL-10).11-27-2008
20080294024Glucose meter system and monitor - A handheld portable glucose meter includes a glucose sensor having a sensor output related to glucose in a blood sample. A display is configured to display information to a user. A manual input is configured to receive user input data from the user. Communication circuitry is configured to send and/or receive data to and/or from a remote location. A controller controls operation of the handheld portable glucose meter.11-27-2008
20080294023Device, System, and Method for In-Vivo Analysis - A device, system and method for in-vivo analysis. An autonomous in-vivo device may include a magnet to detain at least a portion of a sample collected from a body lumen; a sensor to sense a property of the detained sample portion; and a transmitter to transmit data of the sensed property.11-27-2008
20120046529PHYSIOLOGICALLY ACTIVE SUBSTANCE COLLECTING DEVICE - A physiologically active substance collecting device, includes: a collecting section brought into contact with a body surface of a living organism to acquire a physiologically active substance from the body surface; and a liquid sending means for sending a solvent to the collecting section, the collecting section having an aperture at which the solvent flown by being sent from the liquid sending means contacts the body surface.02-23-2012
20100240969Systems and Methods for Transdermal Secretion Detection - Various embodiments of the present invention provide systems and methods for detecting chemicals. As an example, a system is disclosed that includes a chemical sensor, a processor, and a computer readable medium. The computer readable medium includes instructions executable by the processor to: receive a plurality of outputs from the chemical sensor; calculate a baseline value using the plurality of outputs from the chemical sensor; and report an event when the baseline value is exceeded.09-23-2010
20110301442DIAGNOSTIC ANALYTE COLLECTION DEVICE BASED ON FLEXIBLE POLYMERS WITH BIOLOGICAL SURFACE MODIFICATION AND MICROFLUIDIC FUNCTIONALITY - The invention relates to a device for detecting analytes. In order to supply a need in alternative prenatal diagnostic methods which do not include the risks known in the state of art, the present invention provides a device for detecting analytes, including a polymer fiber and capturing molecules, wherein the capturing molecules bind to an analyte and/or a linker molecule.12-08-2011
20110288386On-Body Medical Device Securement - Devices and methods for maintaining a medical device on-body are provided. Embodiments include medical device securement systems having first and second on-body securement elements. Also provided are systems and kits for use maintaining a medical device on-body.11-24-2011
20110295091METHOD AND SYSTEM FOR MANAGING PATIENT DATA - The present invention relates to a method and apparatus for managing patient data. In one aspect, the invention relates to a system for managing patient data having many instruments. The instruments have a sampling member for sampling a body fluid from a patient and are in direct communication with at least one other instrument.12-01-2011
20110295090Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant.12-01-2011
20110295089Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant.12-01-2011
20110295088Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant.12-01-2011
20090099427MICRONEEDLE ARRAY WITH DIVERSE NEEDLE CONFIGURATIONS - The invention relates to a surface penetration device, a method to use the device, and an analyte monitor. Embodiments of the surface penetration device include a substrate with first and second surfaces, and first and second tissue piercing elements, the elements differing in configuration, but each associated with the first surface of the substrate. At least some of the tissue piercing elements have a distal and a proximal opening and a lumen extending between the openings. The proximal openings are in fluid communication with an opening in the second surface of the substrate. Embodiments of the analyte monitor include the features of the penetration device plus an analyte sensor that detects an analyte in a fluid. Embodiments of the method of penetrating tissue include providing a surface penetration device and urging the surface penetration device against a tissue surface until some of the first and second tissue piercing elements penetrate the tissue surface.04-16-2009
20090149725Integrated fluid analyte meter system - An integrated meter system for determining information related to an analyte of a fluid sample includes a meter including a housing and a plurality of test sensors. Each of the plurality of test sensors includes a penetrating member, a testing portion, and a channel. The channel is adapted to receive the fluid sample. The test sensors are removably located within the housing. At least one of the test sensors is removably connected to an adjacent test sensor. The integrated meter system also includes a test-sensor advancement mechanism that is configured to advance the test sensors.06-11-2009
20120108922Implantable Medical Sensor and Fixation System - An implantable medical device, such as a sensor for monitoring a selected internally detectable physiological parameter of a patient, is attached to a fixation member that is deployable within the patient to position and orient the sensor to enable it to perform its function. The fixation member may be configured to lie in a single plane when deployed or may be tubular in shape. The attachment of the housing and fixation member includes providing the fixation member with a linear attachment strut that is non-circular in cross section and providing the housing with external members that define an elongate channel, non-circular in cross section and receptive to the attachment strut. The attachment strut can be inserted transversely into the channel and the external member can be crimped over the strut to secure the housing and fixation member together.05-03-2012
20120108921GASTRIC BANDING SYSTEM ADJUSTMENT BASED ON A SATIETY AGENT CONCENTRATION LEVEL - Methods and devices are provided for adjusting a gastric band to obtain a predetermined optimal expression of hormones. These hormones may be used to control appetite, metabolism and other weight control mechanisms. Ultimately, weight-loss efficacy is desired by tightening or loosening the gastric band based on hormone response.05-03-2012
20100056885IMPLANTABLE BIOSENSOR DEVICES FOR MONITORING CARDIAC MARKER MOLECULES - An implantable biosensor system is disclosed for determining levels of cardiac markers in a patient to aid in the diagnosis, determination of the severity and management of cardiovascular diseases. The sensor includes nanowire sensor elements having a biological recognition element attached to a nanowire transducer that specifically binds to the cardiac marker being measured. Each of the sensor elements is associated with a protective member that prevents the sensor element from interacting with the surrounding environment. At a selected time, the protective member may be disabled, thereby allowing the sensor element to begin sensing signals within a living body.03-04-2010
20090062630Sensor permitting detection of a substance in the body of a living being - A sensor is disclosed for permitting detection of a substance in the body of a living being. In at least one embodiment, the sensor includes probe molecules, for binding the substance that is to be detected, and marking elements designed in such a way that the binding of the probe molecules to the substance to be detected is detectable by way of an imaging modality. For example, antigens or pathogens that are present only in a low concentration can be detected.03-05-2009
20090287069METHODS AND APPARATUS FOR REPEATED ISCHEMIC CONDITIONING TREATMENT OF HYPERTENSION AND OTHER MEDICAL CONDITIONS - Methods for ischemic conditioning treatments of a chronic medical condition are provided. Baseline disease-related parameters of a patient with a chronic medical condition are measured. Ischemia is induced in the patient by occluding and releasing arterial flow in one or more extremities of the patient. Post-ischemia parameters in the patient are measured. The baseline and post-ischemia parameters are compared to provide an assessment of an ischemic conditioning treatment of a chronic medical condition. The repeated, scheduled delivery of ischemic conditioning provides a beneficial, therapeutic effect on the chronic medical condition. Also provided is a device for pulse oximetry during periods of absent or low pulsatile blood flow including an artificial pulse generator as well as the use of said device in assessment of ischemic conditioning.11-19-2009
20080269574Diagnosing Peripheral Vascular Disease by Monitoring Oxygen Saturation Changes During a Hyperemia Phase - Peripheral vascular disease is diagnosed through measurements of oxygen saturation. In a specific implementation, peripheral vascular disease is diagnosed based on changes in oxygen saturation in tissue. Ischemia is induced, and then measurements of changes in oxygen saturation in tissue are made. Based on changes in oxygen saturation during a hyperemia phase, a diagnosis is provided of whether a patient has or does not have peripheral vascular disease.10-30-2008
20090187083CATHETER - A catheter and associated method for taking a plurality of samples from within a length of a blood vessel. The catheter includes an elongate central body arranged to be inserted into and positioned along a central region of a blood vessel. A plurality of collection areas are defined along the elongate central body for collecting samples at the central region of the blood vessel. A plurality of mixers are provided radially outwardly of the elongate central body and arranged to create a flow of blood from a boundary layer at a wall of the blood vessel to the elongate central body. This enables the collection areas to collect samples from the boundary layer.07-23-2009
20090088613CONTINUITY CIRCUITS FOR DETECTING ACCESS DISCONNECTION - A monitor for an extracorporeal therapy access site is disclosed. The monitor includes a bandage atop or adjacent the access site and a sensor for monitoring the bandage. The bandage includes a layer of polymer that expands when wetted with blood. The expansion causes a break in continuity of the sensor, or in an alternate embodiment, causes a sensor to cease detecting a target. When the break occurs, the control circuit monitoring the bandage sends a signal that a break has occurred, and a remote monitor then takes appropriate action, such as ceasing therapy, sending an alert, or sounding an alarm. In another embodiment, connecting wires in a continuity circuit are held apart by a polymer that dissolves when contacted by blood. If a leak occurs and a small portion of the polymer dissolves, the wires make contact, thus detecting a blood leak.04-02-2009
20110172508SAMPLING DEVICE INTERFACES - The present invention generally relates to systems and methods for delivering and/or withdrawing a substance or substances such as blood or interstitial fluid, from subjects, e.g., from the skin and/or from beneath the skin. In one aspect, the present invention is generally directed to devices and methods for withdrawing or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a fluid transporter (for example, one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some cases, the device may be self-contained, and in certain instances, the device can be applied to the skin, and activated to withdraw blood from the subject. The device, in some cases, may be interfaced with external equipment to determine an analyte contained within a fluid contained within or collected by the device. For example, the device may be mounted or engaged on an external holder, the device may include a port for transporting fluid out of the device, the device may include a window for interrogating a fluid contained within the device, or the like. The device, or a portion thereof, may then be processed to determine the blood and/or an analyte within the blood, alone or with an external apparatus. For example, blood may be withdrawn from the device, and/or the device may contain sensors or agents able to determine the blood and/or an analyte suspected of being contained in the blood. Other aspects of the present invention are directed at other devices for withdrawing blood (or other bodily fluids, e.g., interstitial fluid), kits involving such devices, methods of making such devices, methods of using such devices, and the like.07-14-2011
20090292183BIOLOGICAL INFORMATION, ACQUISITION METHOD AND INSTRUMENT, AND PHYSIOLOGICALLY-ACTIVE SUBSTANCE MEASUREMENT METHOD AND INSTRUMENT - A biological information acquisition method for acquiring information on a living body on a basis of a quantified value of a physiologically active substance originated from the living body, includes a step of collecting the physiologically active substance from a body surface of the living body.11-26-2009
20090043177METHOD FOR INTEGRATING FACILITATED BLOOD FLOW AND BLOOD ANALYTE MONITORING - A method for the integrated facilitization of blood flow and monitoring of blood analyte concentration (for example, blood glucose concentration) includes implanting a stent configured to facilitate blood flow into a cardiovascular system of a user's body with the stent having attached thereto a continuous blood analyte determination module of a blood analyte monitoring system. The method also includes disposing a reader module of the blood analyte monitoring system external to the user's body and in proximity to a portion of the user's skin layer and monitoring blood analyte concentration via (i) emitting an RF carrier signal from the reader module toward the stent; (ii) receiving the RF carrier signal at a reflection antenna of the continuous blood analyte determination module; (iii) reflecting a modulated signal by the reflection antenna with the modulated signal being encoded with a blood analyte concentration determined by a sensor of the continuous blood analyte determination module; (iv) receiving the modulated signal by the reader module; and (v) decoding the analyte concentration from the modulated signal by the reader module.02-12-2009
20090292185Sensor Inserter Assembly - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion.11-26-2009
20090292184Sensor Inserter Assembly - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion.11-26-2009
20110270055MEASUREMENT SYSTEM FOR AN ANALYTE DETERMINATION AND A METHOD - A measurement system and method for operating a measurement system is disclosed for an analyte determination. The system includes an analysis unit, which is configured to determine a measured analyte value for a body fluid specimen that is applied, a fingerprint sensor, which is configured to detect fingerprint sensor signals for one or various users, and a control unit, which is connected to the analysis unit and the fingerprint sensor unit for data transmission. The control unit is configured to perform a user identification using the detected fingerprint sensor signals and after successful user identification to enable a determination of a measured analyte value with the analysis unit for an identified user. The control unit is additionally configured to analyze the detected fingerprint sensor signals and optionally additional detected fingerprint sensor signals in addition to the user identification in order to provide control signals for performing additional measurement system functions.11-03-2011
20110270054ASSAY FOR POSITIONING A FEEDING TUBE AND METHOD THEREOF - The present invention discloses a bedside or point of care assay for properly positioning a feeding tube in the stomach of a patient based on detecting the presence of a hydrolytic enzyme found in the stomach by an ester substrate which can be impregnated on a pH strip. The application of this test reduces the risk of tube misplacement and the resulting harm to the patient that occurs in the event of tube misplacement.11-03-2011
20110208021Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant.08-25-2011
20110208020System with a reservoir for perfusion management - A system for perfusion management that monitors, maintains, diagnoses, or treats perfusion deficiencies.08-25-2011
20110270053Intra-Oral Detector and System for Modification of Undesired Behaviors and Methods Thereof - Methods, devices and systems are disclosed for use in detecting a number of substances that may be present, whether constantly or intermittently, in the oral cavity and indicative of specific undesirable and/or unhealthy behaviors. Disclosed devices including detectors that indicate the presence of targeted substances qualitatively or quantitatively, may be secured temporarily, semi-permanently or permanently in the oral cavity employing known dental materials and techniques. The disclosed methods and devices enable constant passive monitoring and therefore may aid in the cessation via a number of positive and negative feedback mechanisms, as well as providing additional diagnostic information to healthcare providers.11-03-2011
20080287755METHOD AND APPARATUS FOR TREND ALERT CALCULATION AND DISPLAY - Embodiments of the present invention provide methods, apparatuses, and systems associated with detecting, monitoring, analyzing, and/or displaying analyte level trends in a body. In an embodiment, there is provided a method comprising obtaining a plurality of analyte measurements from a body using an analyte sensing device, and selecting two or more measurements of the plurality of measurements to calculate and display on a device associated with the analyte sensing device a rate of change of the analyte over a period of time spanning the two or more measurements.11-20-2008
20090264717ANALYTE METER PROTECTORS AND METHODS - Analyte meter protectors, meters that include the same, and methods.10-22-2009
20110208022DEVICE AND METHODS FOR SAMPLING PROSTATE FLUID - Disclosed are devices and methods to improve sampling of prostate secretions for purposes of diagnoses, staging, assessment of malignant potential, prognosis.08-25-2011
20090082646ACCESS DISCONNECT DETECTION SYSTEM - An access site disconnection system and method are disclosed. Radio frequency transmitters and receivers are placed near an access site. When a patient receives dialysis treatment, wetness may arise from blood if the access needle becomes disconnected from the access site. Radio-frequency transmitters are mounted on or near gauze or other absorbent material placed adjacent the access site, as are radio-frequency receivers. After the sensors are placed, the dialysis machine and radio-frequency control circuit may be initialized or baselined, and dialysis treatment, such as hemodialysis, begun. If blood leaks from the access site, such as if the access needle is dislodged, the blood attenuates the radio frequency transmissions, which are detected by the receivers. A signal is sent to a controller or to an output device to raise an alert or sound an alarm.03-26-2009
20090143654BIOLOGICAL MEASUREMENT SYSTEM - This invention measures cerebral blood volume changes to evaluate, from properties of low-frequency components of such changes and heart rate changes calculated by analysis, a distribution of cerebral blood vessel hardness and its with-time change to thereby estimate and display diseased and dangerous portions based on the evaluation. Briefly, the above-noted object is attainable by a biological measurement system having a cerebral blood volume measurement unit which measures a regional cerebral blood volume of a body under test, an analyzer unit that analyzes a signal measured by the cerebral blood volume measurement unit, an extraction unit for extracting, based on an output of the analysis unit, information concerning a regional cerebral blood vessel state of the test body, and a display unit which displays a measurement result of the cerebral blood volume measurement unit, an analysis result of the analyzer unit or an extraction result of the extraction unit.06-04-2009
20090012376Continuous Analyte Monitor and Method of Using Same - The use of an analyte-monitoring device for continuously monitoring analytes within a bodily fluid bypass flow path. A method of monitoring analytes in a patient by continuously monitoring analytes present in a bodily fluid of that patient within the bodily fluid bypass flow path is provided.01-08-2009
20090082647DETECTING ACCESS DISCONNECT USING NEEDLE SLEEVE - An access needle for extracorporeal therapy is equipped with a mount and a sleeve having a metal or magnetic component at its distal end. The mount includes a sensor for detecting when the distal end is pressed against the mount. The sensor is a hall-effect sensor or a proximity sensor. When therapy is begun, the sleeve is rolled up and urged against the mount, exposing the needle for use with the patient. While the sleeve, and the piece of metal or magnet, remains in contact with the sensor, the needle has not been dislodged and therapy may continue. If the needle is dislodged, the sleeve pushes away from mount, moving the metal or magnet away from the sensor. The sensor notes the dislodgement and sends a signal to alert the patient or a caregiver.03-26-2009
20110230737DEVICE AND METHOD FOR EARLY DIAGNOSIS AND PROGNOSIS OF HEALING PROGRESSIONS, IN PARTICULAR FOR BONE INJURIES - The invention relates to a device comprising: i) a sample-receiving unit (09-22-2011
20110230736DEVICE AND METHOD FOR DRUG EVALUATION AND LOCAL TREATMENT - Described here are devices, systems, and kits for delivering substances to tissues. The devices generally include one or more chambers (09-22-2011
20080234559Analyte Meter Protectors and Methods - Analyte meter protectors, meters that include the same, and methods.09-25-2008
20080319284METHOD FOR TRAINING A USER IN RECOGNITION OF THE USER'S BODILY FLUID ANALYTE CONCENTRATION AND CONCENTRATION TRENDS VIA USER-PERCEIVED SENSATIONS - A method for training a user in recognition of the user's bodily fluid analyte concentration and concentration trends includes monitoring a user's bodily fluid analyte concentration (for example, a user's whole blood glucose concentration) with an analyte monitoring module of a device for training a user in recognition of the user's bodily fluid analyte concentration. The method also includes generating, at a predetermined time interval, using a generation module of the device, a user-perceived sensation (e.g., a user-perceived vibratory sensation) that is proportional the user's bodily fluid analyte concentration in a predetermined manner.12-25-2008
20110230735ANALYTE SENSOR APPARATUSES HAVING IMPROVED ELECTRODE CONFIGURATIONS AND METHODS FOR MAKING AND USING THEM - Embodiments of the invention provide analyte sensors having optimized elements and/or configurations of elements as well as methods for making and using such sensors. Typical embodiments of the invention include glucose sensors used in the management of diabetes.09-22-2011
20090105563BIOSENSOR AND COMPONENT CONCENTRATION MEASURING APPARATUS - An object of the invention is to provide a component concentration measuring apparatus by blood sampling by laser perforating, capable of preventing leak of an abnormal odor generated during laser perforating, and improving user's convenience. In a component concentration measuring apparatus of the invention, a slide sheet 04-23-2009
20090221885Optical Window Assembly for Implantable Medical Device - Embodiments of the invention are related to optical window assemblies for implantable medical devices, amongst other things. In an embodiment, the invention includes an optical window assembly for a medical device. The assembly can include a ferrule defining an aperture and a spacer ring disposed within the aperture. The assembly can also include an optical window coupled to the metal ferrule and the spacer ring. In an embodiment, the invention includes an implantable medical device including a housing and an optical window assembly coupled to the housing. In an embodiment, the invention can include a method of manufacturing a medical device. The method can include brazing a spacer ring to a metal ferrule, coupling an optical window to the spacer ring and the metal ferrule with a bonding glass material, depositing a chemical sensing element over the optical window, and coupling a porous cover layer to the spacer ring and the ferrule with an adhesive. Other embodiments are also included herein.09-03-2009
20090247838ANALYTE TESTING DEVICE - The present invention is a testing device for testing analyte levels in bodily fluids. The testing device comprises memory (10-01-2009
20090240122INTRAJUGULAR CATHETER - A catheter for insertion into a vascular system of a patient and for directing fluid flow includes a catheter body having a longitudinal axis and longitudinally spaced proximal and distal catheter ends with an intermediate catheter portion defined therebetween. An intermediate catheter outlet in the catheter body is located in the intermediate catheter portion and is spaced longitudinally from the proximal and distal catheter ends. A first lumen is defined within the catheter body and has longitudinally spaced proximal and distal first lumen ends with a reversing bend located therebetween, the first lumen providing fluid communication between the proximal catheter end and the intermediate catheter outlet. The reversing bend is located longitudinally between the intermediate catheter outlet and the distal catheter end. The reversing bend directs fluid flow to turn approximately 180° as the fluid flows through the first lumen. A method of using the catheter is also described.09-24-2009
20100152556APPARATUS FOR MEASURING BIOLOGICAL INFORMATION AND EARPHONE HAVING THE SAME - Disclosed is an apparatus for measuring biological information and an earphone having the same for contacting with a uniform pressure a user body part using an elastic member. The apparatus includes a first housing; a second housing foldably connected with the first housing; a third housing foldably connected with the second housing and provided with a sensor for measuring the biological information; a plurality of joint parts for connecting the housings to be folded or unfolded to each other; one or more locking parts for restraining or releasing the housings to be folded or unfolded to each other; and the elastic member for applying the same pressure to make the sensor contact with the user's body by enabling the respective housings to be folded or unfolded using a stress-strain.06-17-2010
20100274107POLYMER MEMBRANES FOR CONTINUOUS ANALYTE SENSORS - Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species.10-28-2010
20100274108Method and Apparatus for Providing Rechargeable Power in Data Monitoring and Management Systems - Method and apparatus for providing a disposable power supply source integrated into the housing of the transmitter unit mount that is placed on the skin of the patient, and configured to receive the transmitter unit is disclosed. The transmitter unit mount is configured to be disposable with the analyte sensor so that power supply providing power to the transmitter unit is also replaced. The transmitter unit may include a rechargeable battery that is recharged by the power supply unit of the transmitter unit mount when the transmitter is mounted to the transmitter unit mount. Other energy store configurations including single large capacitor (supercap) or a capacitor and DC/DC converter configurations are disclosed.10-28-2010
20090318784Devices and Methods for Detecting B-Haematin and Haemozoin - In the application, the change in the magnetic state of the haemoglobin caused by the malarial infection is exploited by detecting suitable properties of haemozoin which are dependent on the application of a magnetic field. FIG. 12-24-2009
20100160748Analyte Monitoring Device and Methods of Use - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor.06-24-2010
20100185065SYSTEM AND METHODS FOR PROCESSING ANALYTE SENSOR DATA - Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.07-22-2010
20100168534BLOOD INSPECTION DEVICE - A blood inspection device using laser as puncture means. The blood inspection device has an electric power source control circuit for controlling electric power supply of an electric power source section including an electric power source for driving an electric circuit for measurement and also including an electric power source for driving a laser emission device. When a battery is used as the electric power source, the circuit measures the remaining level and voltage of the battery to control the power source so that electric power shortage does not disenable measurement.07-01-2010
20110060196Flexible Mounting Unit and Cover for a Medical Device - Generally, embodiments of the present disclosure are directed to an adhesive mounting unit that is formed from a nonwoven polymeric material that is breathable, flexible, waterproof and durable. Additionally, the adhesive mounting unit of the present disclosure includes a retention mechanism that is insert molded directly into or on the mounting unit such that the mounting unit and retention mechanism form a single unitary structure.03-10-2011
20100234702DEVICE FOR ACCURATELY MEASURING CONCENTRATION OF COMPONENT IN BLOOD AND CONTROL METHOD OF THE DEVICE - A measurement device includes an electronic component device, a perspiration acceleration device, and a perspiration collection device. The perspiration acceleration device or the perspiration collection device is removably coupled to the electronic component device. The electronic component device is attached to a measurement site with a belt. A perspiration accelerating performance is made with respect to the measurement site with the perspiration acceleration device coupled to the electronic component device, and thereafter, the perspiration acceleration device is replaced with the perspiration collection device with the electronic component device attached to the measurement site, and the perspiration collection and measurement computation performance are made.09-16-2010
20100240970METHOD FOR AN IN VIVO MEASUREMENT USING A DEVICE IMPLANTED IN A PATIENT, AND CORRESPONDING DEVICE - An embodiment of the present invention relates to a device, which can be implanted into a patient, for an in vivo measurement. In an embodiment, the device includes a catheter for guiding a sample of the patient town analysis unit in the device. A measurement result is determined in the analysis unit by analyzing the sample with the aid of a reagent. In an embodiment, the device furthermore includes an interchange chamber, with the aid of which the reagent can be removed from the device or can be inserted into the device. The interchange chamber has a connector allowing removal or insertion of the reagent while the device is implanted.09-23-2010
20110112384Medical system having consumables monitoring - The invention proposes a medical system which comprises a central control unit which is set up to display at least one diagnostic measured value using a display element. The medical system also comprises at least one invasive unit, wherein the invasive unit has at least one invasive consumable. The invasive consumable is set up to invasively intervene in a tissue of a patient. The invasive unit has at least one contactlessly readable electronic identifier for storing at least one piece of information. The central control unit is set up to electronically read the at least one piece of information in the electronic identifier. The central control unit and the invasive unit are functionally independent of one another such that the respective function of the central control unit and of the invasive unit can be performed independently of the presence of the respective other unit.05-12-2011
20120245438MEDICAL SYSTEM HAVING PLUG AND PLAY FUNCTION - A medical system is disclosed, which can be useable in particular for monitoring and/or controlling at least one bodily function of a user. The medical system comprises a control device and at least one medical user element embodied separately from the control device. The medical user element and the control device are designed to exchange data wirelessly. The medical system is designed to enable an automatic assignment step, wherein an exchange of personal data between the medical user element and the control device is enabled by the automatic assignment step. The medical system is furthermore designed to automatically initiate the automatic assignment step by means of an assignment coupling between the medical user element and the control device. The medical system is furthermore designed to enable a separation of the assignment coupling for medical operation of the medical system after the assignment step.09-27-2012
20110130637PROTEIN PRODUCT FOR MODIFYING CARDIOVASCULAR HEALTH - A composition for use in the treatment or prophylaxis of conditions mediated by endothelial function in mammals is provided. The composition includes a milk protein hydrolysate generated by treating milk or milk whey protein with a proteolytic enzyme having subtilisin or subtilisin-like activity and/or glutamyl endopeptidase or glutamyl endopeptidase-like activity. The composition is useful in the management of vascular conditions.06-02-2011
20120143023SYSTEM AND METHOD FOR FACIAL NERVE MONITORING DURING FACIAL SURGERY - An apparatus for monitoring the activity of a surgeon. At least one wireless sensing unit is provided for monitoring potential damage to a nerve and is located at a first location of a body being operated on by a surgeon. The wireless sensing unit senses a change in the body at the first location resulting from potential damage to the nerve occurring at a second location of the body remote from the first location. The wireless sensing unit produces a wireless sensed change output signal indicative of the change in the body which is received by a receiver and generates a corresponding received output signal. An analyzer unit receives and analyzes the received output signal to determine the change in the body. An indicator responsive to the output of said analyzer unit indicates the change in the body to indicate the potential damage to the nerve the surgeon.06-07-2012
20090069650Integrated Analyte Sensor And Infusion Device And Methods Therefor - Method and system for providing an integrated analyte monitoring system and on-body patch pump with multiple cannulas and a sensor combination is provided.03-12-2009
20090069649Method and System for Providing Analyte Monitoring - Methods and apparatuses for determining an analyte value are disclosed.03-12-2009
20090036758SIGNAL PROCESSING FOR CONTINUOUS ANALYTE SENSOR - Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.02-05-2009
20110009717BLOOD SAMPLING DEVICE - A blood sampling device useful for collecting a blood sample from a separate vascular access device is described herein. The blood sampling device includes a body shaped and sized for partial insertion into a separate vascular access device. The body includes a reservoir defined within the body, which has an internal volume sufficient to contain enough blood for use in a diagnostic blood test. The body also includes a gas permeable vent disposed on the body, in which the gas permeable vent is in gaseous communication with the reservoir. When connected to a separate vascular access device the blood sampling device collects a blood sample as blood flows into the reservoir from the separate vascular access device and as gases pass out the reservoir via the gas permeable vent.01-13-2011
20100331635Finger-Clipped Oximeter with Finger Pressed Plate - The present invention discloses a finger-clipped oximeter comprising: an upper case (12-30-2010
20100331634HYDROGEL IMPLANT FOR SENSING METABOLITES IN BODY TISSUE - An implant (12-30-2010
20110040160ANALYSIS DEVICE HAVING A DISCARDING MECHANISM - An analyzing device which fits an analyzing instrument 02-17-2011
20110034785Biopolymer resistant devices using coatings with surface energy gradient - A medical device or analytical device comprising a fluid-impervious surface comprising a base surface, at least one distinct region of the base surface covered by a mixed monolayer film, the mixed monolayer film comprising a species having a functional group M1 and a species having a functional group M2 where M1 and M2 have different surface energies, the mixed monolayer forming a surface energy gradient wherein at least one of the species used to form the monolayer on the surface comprises a biopolymer-resistant domain.02-10-2011
20110245634Methods, Systems, and Devices for Analyzing Patient Data - Described herein is a method of analyzing an analyte distribution from discrete, quasi-continuous or continuous measurements to determine a glycemic state of a patient in order to understand how often, and for how long, a patient's post-prandial glucose is out of control without requiring laboratory blood test and especially post-prandial levels laboratory analysis. The systems, devices, and methods assist in predicting risk levels of developing diabetes-associated complications. Therefore applicants have recognized also a need for a tool which facilitates stratification of patients for risk of and/or onset of one or more complications having the same HbA1c level.10-06-2011
20100168535METHODS AND APPARATUSES RELATED TO BLOOD ANALYTE MEASUREMENT SYSTEM - The present invention relates to a blood analyte measurement system for the procurement of blood samples for measurement of blood properties such as analyte concentration or analyte presence. A blood access system can be coupled with a measurement system such as an electrochemical sensor, and can also be used with other measurement modalities. Embodiments of the present invention can facilitate accurate measurement of blood glucose by the clinician in a sterile manner. Embodiments of the present invention can also enable the calibration of the sensor at one or more calibration points. One desired analyte of measurement is glucose for the effective implementation of glycemic control protocols. Embodiments of the present invention can also be used for the measurement of other analytes such as arterial blood gases, lactate, hemoglobin, potassium and urea. Additionally, embodiments of the present invention can function effectively on a variety of blood access points and specifically enables glucose monitoring in an existing arterial line that is already in place for hemodynamic monitoring. The present invention does not consume a significant amount of blood. Some embodiments of the present invention can re-infuse the blood into the patient, which can facilitate operation of the system in a sterile manner.07-01-2010
20110124984Device for Aliquoting and Filtering Blood - Device for aliquoting and filtering blood, comprising: an element (05-26-2011
20110124986Microchip, Blood Analysis System and Blood Analysis Method - A microchip to be installed in a blood analysis system for measuring properties of blood, provided with a plurality of channels through which blood passes, wherein only each of first subset channels among the plurality of channels is provided with a first plurality of barriers for locally changing a direction of blood flow, in a blood flow direction on a wall face demarcating the channels, and among the first plurality of barriers, barriers which are adjacent to each other in the blood flow direction differ in shape from each other.05-26-2011
20110124985VISCOSIMETRIC BIOSENSOR FOR MONITORING ANALYTE LEVELS - The invention relates to a viscosimetric sensor for monitoring an analyte level in a patient or in body fluids ex vivo. In particular, the invention relates to a sensor for monitoring analytes, such as glucose levels in a patient. The sensor comprises at least two hermetically closed chambers (05-26-2011
20110077477SENSORS WITH THROMBORESISTANT COATING - Embodiments of the present invention relate to analyte sensors comprising a heparin benzalkonium antithrombogenic coating, and methods of coating analyte sensors.03-31-2011
20110092783IN VIVO MICRO-INVASIVE INVESTIGATION DEVICE INCLUDING A METAL GUIDE - The invention relates to an analysis device, wherein said system includes at least one metal guide at one end of which is provided at least one series of pits to which are directly coupled reagents specific to a substrate, said end being a perforating one, while the other end is intended for controlling said guide and is optionally associated with a suction system. The guide may be inserted into a protection system that is removable at the level of the functionalised end, up to the micro-analysis and/or micro-sampling site, and/or into a medical instrument having an inner channel in which said guide may slide. The present invention also relates to the use of such a device for making a tool for diagnosing cancer, an inflammation, an infection, a neurodegenerative disease or a graft rejection in a patient, preferably by transparietal delivery. The invention further relates to a method for the ex vivo analysis of a substrate using such a device.04-21-2011
20090048499Sensor film for transcutaneous insertion and a method for making the sensor film - There is provided a thin film (02-19-2009
20090312614Transdermal Analyte Sensor Assembly and Methods of Using the Same - A transdermal test sensor assembly adapted to determine an analyte concentration of a fluid sample is disclosed. The assembly comprises a sensor support including at least one reservoir adapted to hold a liquid. The assembly further comprises a test sensor being coupled to the sensor support. The test sensor forms at least one aperture therein. At least a portion of the at least one aperture is adjacent to the at least one reservoir. The assembly further comprises a hydrogel composition positioned on the test sensor. The hydrogel composition is linked to the at least one reservoir via the at least one aperture.12-17-2009
20090216094Method of deriving a quantitative measure of a degree of calcification of an aorta - A method of deriving a quantitative measure of a degree of calcification of a blood vessel such as an aorta by processing an image such as an X-ray image of at least a part of the blood vessel containing said calcification comprises: taking a starting set of digital data representative of an image of at least part of a blood vessel containing a calcification set against a background; estimating the boundary of the calcification; using inpainting to replace digital data in said starting set representing the calcification with data extrapolating the boundary of the background to extend over the area of calcification, and so generating an inpainted set of digital data; and computing the difference between the starting set of digital data and the inpainted set of digital data to obtain a quantitative measure of the degree of calcification of the blood vessel.08-27-2009
20100069726COMPOSITIONS AND METHODS FOR RAPID ONE-STEP DIAGNOSIS - Devices for fast easy monitoring of analyte levels, disease, or other physiological changes are provided. In some cases, the devices may include particles or the like that can be placed and read at the site of detection, typically on or in the skin or mucosa. In one embodiment, the particles may include anisotropic particles. Typically the devices will typically provide a visual colorimetic signal, but other signals are possible, such as smell, taste (e.g., release of food acceptable flavor), or tactile (e.g., shape change). The devices are preferably single use, disposable devices, although some may be able to provide multiple readings over a period of time. These devices may be used with any patient and are particularly useful for pediatric and elderly patients, as well as for the military, and people without health insurance. The devices can be used to assess when intervention may be required without expensive testing at a physician's office, or simply for routine maintenance of those who are concerned about their health.03-18-2010
20110098541Method and apparatus for penetrating tissue - These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generator moves the member along a path out of a housing having a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. A cartridge houses the penetrating member. The cartridge has first and second seals coupled to the penetrating member to maintain a sterile environment around a portion of the penetration member prior to penetrating member actuation. A user interface is configured to relay at least one of, penetrating member performance or a penetrating member setting.04-28-2011
20110077479Method and System for Providing Basal Profile Modification in Analyte Monitoring and Management Systems - Method and system for providing basal profile modification in insulin therapy for use with infusion devices includes periodically monitoring the analyte levels of a patient for a predetermined period of time in order to determine, based on the monitored analyte levels, an appropriate modification factor to be incorporated into the underlying basal profile which was running at the time the periodic monitoring of the analyte levels were performed.03-31-2011
20110077478Body fluid sampling module with a continuous compression tissue interface surface - A body fluid sampling device includes a housing, a penetrating member positioned in the housing and a test strip. A compliant front end is coupled to the housing. The compliant front-end includes a rigid member with an interior aperture to receive the body fluid from a wound site.03-31-2011
20110152643"Band-aid"-type potassium ion (K+) biosensor - Potassium ion (K+) is important in regulating normal cell function in the human body, specifically the heartbeat and the muscle function. It is important to be able to monitor potassium ion concentrations in human fluids. This invention describes a novel concept for a potassium ion biosensor that accurately, rapidly, and efficiently monitors the presence and records the concentration of potassium ions with high specificity, not only in serum and urine, but also in the sweat or even eye fluid. This specific biosensor design utilizes a nanomanufacturing technique, i.e. electrospinning, to produce advanced nano-bio-composites that specifically trace even minute quantities of potassium ions through the use of selective bio-receptors (ionophores) attached to high surface area nanofibers. Electroactive polymers are then employed as transducers to produce an electronic (rather than ionic) output that changes instantly with the change in K+ concentration. Such biosensors may be manufactured in a skin patch configuration.06-23-2011
20110152641DISPOSABLE COVER FOR USE IN AN INCUBATOR FOR PREMATURE INFANTS - The invention refers to a disposable cover for use in an incubator for premature infants comprising a moisture-pervious surface layer and a preferably moisture-impervious back sheet, wherein the total weight of the cover before use is communicated to the caregiver by indication on said cover, a label accompanying said cover or on the package for said cover. The cover may further be provided with a wetness indicator.06-23-2011
20120035441MOUNT UNIT, SENSOR UNIT, MEASUREMENT APPARATUS AND SENSOR FIXATION METHOD - A mount unit 02-09-2012
20080255434METHOD AND APPARATUS FOR PROVIDING DATA PROCESSING AND CONTROL IN MEDICAL COMMUNICATION SYSTEM - Methods and apparatus for providing data processing and control for use in a medical communication system are provided.10-16-2008
20120277551INTERSESSION MONITORING FOR BLOOD FLUID REMOVAL THERAPY - Methods for monitoring patient parameters and blood fluid removal system parameters include identifying those system parameters that result in improved patient parameters or in worsened patent parameters. By comparing the patient's current parameters to past parameters in response to system parameters or changes in system parameters, a blood fluid removal system may be able to avoid future use of parameters that may harm the patient and may be able to learn which parameters are likely to be most effective in treating the patient in a blood fluid removal session.11-01-2012
20120203084POSITIONING SYSTEM, APPARATUS, AND METHOD FOR WIRELESS MONITORING OF ESOPHAGEAL pH VALUE - A positioning system, an apparatus, and a method for wireless monitoring of esophageal pH value. The positioning system includes an internal transmitting apparatus and an external recording apparatus. The external recording apparatus includes a second element, and the second element of the external recording apparatus cooperates with a first element of the internal transmitting apparatus. If the external recording apparatus detects that the internal transmitting apparatus is not located in the preset region, alerting action is conducted under the control of a micro-processor. The external recording apparatus periodically detects the intensity of a signal received by a second wireless transceiver module, under the control of the micro-processor, and if the signal intensity is not within the preset range, the alerting action is conducted under the control of the micro-processor.08-09-2012
20100280341POLYMER MEMBRANES FOR CONTINUOUS ANALYTE SENSORS - Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species.11-04-2010
20110213225Medical devices and methods - Methods and devices to monitor an analyte in body fluid are provided. Embodiments include continuous or discrete acquisition of analyte related data from a transcutaneously positioned in vivo analyte sensor automatically or upon request from a user.09-01-2011
20110178378TRANSCUTANEOUS ANALYTE SENSOR - The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.07-21-2011
20110152642DETECTION OF BUBBLES DURING HEMODYNAMIC MONITORING WHEN PERFORMING AUTOMATED MEASUREMENT OF BLOOD CONSTITUENTS - Example embodiments of the present invention provide methods and apparatuses that enable the detection of bubbles so that hemodynamic performance can be assured following an automated blood analyte measurement. An example apparatus according to the present invention comprises a blood access system, adapted to remove blood from a body and infuse at least a portion of the blood back into the body. The infusion of at least a portion of the blood back in to the body can be done in a manner to assure that no bubbles of clinical significance are injected into the patient. Additionally an example embodiment can assess for the presence of bubbles in the fluid column that can affect hemodynamic monitoring performance. If a condition exists where hemodynamic monitoring performance cannot be assured, an example embodiment can provide appropriate warning or corrective actions.06-23-2011
20120203083Biologocal Test Kit - The biological test kit is a device for drawing and, optionally, testing biological samples. The biological test kit is an array of Lancets set in wells in a rigid base. Each lancet well is covered by a protective cover which when deformed permits the lancet to puncture a user or other patient. In one embodiment the biological test kit employs distinct covers for each lancet and in another the covers are formed from sheet material formed into blisters which cover the lancet.08-09-2012
20120302844SKIN MOUNTED MEDICAL PATCH DEVICE - Medical patch device mountable on skin for drug delivery or analyte sensing, including a mounting base (11-29-2012
20080214909Catheter With Microchannels For Monitoring The Concentration Of An Analyte In A Bodily Fluid - Catheter for monitoring the concentration of an analyte in a body fluid having an implantable distal area (09-04-2008
20110166431TAPE CASSETTE FOR A MEDICAL HANDHELD DEVICE - A tape cassette for a medical handheld device is disclosed as comprising a carrier tape, which carries test fields for assaying a sample of a human or animal bodily fluid and/or lancets as functional elements, a supply chamber, in which a supply section of the carrier tape comprising unused functional elements is positioned, a winding unit, in order to wind up the carrier tape and draw it through a tape exit opening of the chamber, so that the functional elements may be brought sequentially into a usage position. The carrier tape in the tape exit opening is oriented transversely to the supply section positioned in the supply chamber.07-07-2011
20110054275Mounting Unit Having a Sensor and Associated Circuitry - Disclosed herein is a mounting unit assembly that includes a mounting unit and a sensor integrally formed with the mounting unit such that the mounting unit and sensor form a single unit.03-03-2011
20110054274DEVICE AND METHOD FOR WITHDRAWING BODY FLUID - The invention relates to a device for removing body fluid with a puncture element that can puncture the skin of a body part. The device includes a housing structure for body fluids obtained from the skin puncture and a puncture drive for a back and forth movement of the puncture element. The duration of withdrawal movement is longer than the duration of the forward movement. The puncture drive is designed to withdraw the puncture element in a first withdrawal phase of the withdrawal movement with a maximum withdrawal speed of more than 0.02 m/s. A second retraction phase follows the first retraction phase. Body fluid is collected during the second retraction phase, which has a duration of between 0.3 and 0.8 seconds and/or a retraction speed of between 0.6 and 2 mm/s.03-03-2011
20110054273HEALTH CARE DEVICE - Embodiments described herein relate to health monitoring apparatuses, systems and methods that allow a user to passively monitor her/his health. Embodiments include acquiring chemical substances from a subject's skin (e.g., in sweat and/or sweat vapor or oil excretions) using a sample capture system located on a mounting portion in a fixed location. Embodiments also include analyzing chemical substance(s) acquiring from the subject's skin to generate raw data. Embodiments further include analyzing the raw data to generate health status data for a particular subject.03-03-2011
20110263952INCONTINENCE MANAGEMENT SYSTEM AND DIAPER - An incontinence management system for monitoring wetness in one or more absorbent articles, includes input for receiving one or more sensor signals indicative of a presence of wetness in an absorbent article, processor for processing the one or more sensor signals and for performing an analysis of the signals to characterise wetness events occurring in an absorbent article and user interface for communicating with a user of the system. A mathematical model is used to characterise wetness events, receiving as inputs variables derived from sensor signals and optionally, patient and demographic data. The mathematical model can be configured and/or re-configured utilising observation data obtained while monitoring a patient for wetness. A diaper for use with such as system is also disclosed.10-27-2011
20110257493BODY FLUID SAMPLING DEVICE - Body fluid sampling device comprising a sampling element having a fluid pathway (10-20-2011
20110118569Advanced Detection of Sepsis - The present invention relates to methods, monitors and systems measuring lysophosphatidylcholine, its derivatives and/or procalcitonin as well as at least one clinical marker (e.g. temperature or respiration rate) and/or at least one biomarker for the early detection of sepsis in a subject.05-19-2011
20110118568ASSISTANCE DEVICE - Disclosed is an assistance device which can be used for the puncture into the skin with a puncture tool having a puncture needle and the measurement of a desired component in the blood with a blood glucose monitoring system equipped with a measurement tool. The assistance device comprises a main body which contacts with the skin and a lid which is connected to the main body in a freely openable and closable manner, wherein one of the main body and the lid has a puncture guide for positioning the puncture needle toward a position on the skin to be punctured with the puncture needle, and the other has a blood collection guide for positioning the measurement tool toward the position on the skin punctured with the puncture needle.05-19-2011
20100179401INTEGRATED RECEIVER FOR CONTINUOUS ANALYTE SENSOR - A system is provided for monitoring glucose in a host, including a continuous glucose sensor that produces a data stream indicative of a host's glucose concentration and an integrated receiver that receives the data stream from the continuous glucose sensor and calibrates the data stream using a single point glucose monitor that is integral with the integrated receiver. The integrated receiver obtains a glucose value from the single point glucose monitor, calibrates the sensor data stream received from the continuous glucose sensor, and displays one or both of the single point glucose measurement values and the calibrated continuous glucose sensor values on the user interface.07-15-2010
20100179400SIGNAL PROCESSING FOR CONTINUOUS ANALYTE SENSOR - Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.07-15-2010
20100179399SYSTEM AND METHODS FOR PROCESSING ANALYTE SENSOR DATA - Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.07-15-2010
20100179398Analyte Monitoring Device and Methods of Use - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor.07-15-2010
20100179397Device And Method For Continuous Monitoring Of A Chemical Parameter Of An Individual - A device according to an embodiment of the invention includes a microdialysis catheter having an inlet and an outlet, a pump, and a flow-through monitor. The monitor is configured to analyze dialysate present in perfusion fluid exiting the microdialysis catheter. A chemical parameter may thereby be continuously monitored.07-15-2010
20110137139POST-OPERATIVE BACTERIA TEST STRIP SPOOL AND METHOD - A method for testing body fluids is disclosed. The method includes providing a media-dispensing apparatus, placing at least the distal opening of the elongated tubular member adjacent body fluid (e.g., near a patient's abdomen) or adjacent a medical device such that a portion of the media strip contacts body fluid or the medical device, and advancing the media strip such that the portion of the media strip that contacted the body fluid or the medical device advances at least through the second lumen. Additionally, the step of cutting the media strip with a cutting instrument is also disclosed.06-09-2011
20100113896DIAGNOSTIC DEVICE WITH DISPLAY MODULE AND LEVERAGED COMPONENT CONNECTIONS - The present invention provides an innovative means for efficient and secure component assembly and for ensuring secure electrical connections in a small diagnostics device where available space for fasteners is limited. In one embodiment, principles of leverage are employed to produce a force at a location where space is available. The force is transferred to a different location of the assembly where it is used to maintain secure connections between components.05-06-2010
20110190603Sensor Inserter Having Introducer - A sensor inserter assembly having an introducer configured with one or more holding members to releasably retain a sensor and/or a compressible member.08-04-2011
20090105562SYSTEM AND METHODS FOR SCREENING OR ANALYZING TARGETS - The present invention relates to the system and methods for screening or analyzing targets.04-23-2009
20110152644PROTECTIVE CONTAINER FOR HOLDING REUSABLE DIAGNOSTIC COMPONENTS - A protective container for holding a reusable control part of a transcutaneous sensor system for detecting at least one analyte in a bodily fluid is disclosed. The control part includes at least one coupling, which has at least one sensor coupling for connection to at least one transcutaneous sensor. The protective container has at least one container housing. The control part can be held in the container housing. The container housing is adapted to shield the control part from environmental influences. The container housing also has at least one connector which can be connected to the coupling and seals the latter in a media-tight fashion.06-23-2011
20100030038SIGNAL PROCESSING FOR CONTINUOUS ANALYTE SENSOR - Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.02-04-2010
20100022854Implantable Chip Medical Diagnostic Device for Bodily Fluids - An implantable microchip that is attached to a source of bodily fluids such as a vein, capillary, small artery or other fluid source such as lymph fluid or urine where the fluid flows through the microchip. The microchip can contain a micro-laboratory with reagent sources and micro-canal test chambers. The microchip can contain a readout mechanism where test data is command and/or readout to an external unit. Test results can be detected with an on-chip fluorescence or light detector or an external detector.01-28-2010
20100022855SIGNAL PROCESSING FOR CONTINUOUS ANALYTE SENSOR - Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.01-28-2010
20100016687SIGNAL PROCESSING FOR CONTINUOUS ANALYTE SENSOR - Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.01-21-2010
20090024010Hand-held analysis device having different setting modes - A handheld analysis device for examining a sample of body fluid, such as blood to analyze blood glucose, has a setting mode for changing various device settings to improve the changing of device settings. The handheld analysis device comprises a measurement unit, a microprocessor, a segment display, and an operating element. When the operating element is actuated, the device is placed in a selection mode and further actuation of the operating element, then in one of several setting modes, the user can efficiently change device settings by inputting data and/or control commands.01-22-2009
20110306852Pharmaceutical Dosages Delivery System - Pharmaceutical delivery systems for delivering dosages according to the present invention include a carrier component and a cap configured to seal an internal volume of the carrier component, wherein the cap includes a device that produces a unique current signature. Dosages prepared to be delivered according to embodiments of the invention find use in a variety of different applications, including clinical trials.12-15-2011
20110306853Body fluid sampling/fluid delivery device - A body fluid sampling or fluid delivery system includes a polymeric support and an array of polymeric microneedles coupled to the support, each of a microneedle having a height of 500 to 2000 μm and a tapering angle of 60 to 90°. A plurality of polymeric microchannels are provided with being associated with a microneedle. The plurality of polymeric microchannels are integrally formed with the array of polymeric microneedles without bonding. At least one polymeric reservoir is coupled to the plurality of microchannels.12-15-2011
20120041286Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant.02-16-2012
20120041287Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant.02-16-2012
20120041285Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant.02-16-2012
20120271127SANITARY SWAB COLLECTION SYSTEM, MICROFLUIDIC ASSAY DEVICE, AND METHODS FOR DIAGNOSTIC ASSAYS - Biohazard specimen collection containers are provided with an external disposable skin, that is stripped away and discarded after the biohazardous specimen is collected, thus reducing or eliminating objectionable or dangerous residues on the outside surfaces of the container. Further, we teach that the sample collection container with external disposable skin may also serve as an integrated microfluidic biosample processing and analytical device, thereby providing a single entry, disposable assay unit, kit and system for “world-to-result” clinical diagnostic testing. These integrated assay devices are provided with synergic, multiple safe-handling features for protecting healthcare workers who handle them. The modified collection containers and analytical devices find application, for example, in PCR detection of infectious organisms or pathogenic markers collected on a swab.10-25-2012
20120004521INTEGRATED LANCING TEST STRIP WITH RETRACTABLE LANCET - An integrated lancing test strip device includes a lancet configured to form an incision in tissue and a test strip coupled to the lancet for analyzing body fluid. A retention mechanism acts as a detent to hold the lancet in a static position relative to the test strip before forming the incision. The retention mechanism is configured to release the lancet for retracting the lancet relative to the test strip to reduce smearing of body fluid by the lancet during collection of the fluid with the test strip. In one form, the retention mechanism includes breakable tabs that are broken to release the lancet, and the lancet is retracted via translational movement. The retention mechanism in another form includes one or more dimples that release the lancet when the lancet is retracted via rotational motion. In a further form, the entire integrated device is rotated to collect fluid.01-05-2012
20100179402SYSTEM AND METHODS FOR PROCESSING ANALYTE SENSOR DATA FOR SENSOR CALIBRATION - Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.07-15-2010
20120209090Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant.08-16-2012
20120209091Apparatus and Method for Processing a Set of Data Values - An apparatus for processing a set of data values, a data value representing a physiological measure of a body fluid at a time instant, comprising: an estimated probability function calculator for calculating an estimated probability function associated with the set of data values; a transform calculator for calculating a non-linear transform rule using a predetermined target probability function being different from the estimated probability function, so that the probability function of a set of transform data values is closer to the target probability function than the estimated probability function; and a transformer for applying the transform rule to the set of data values or to at least one further data value not included in the set of data values and sampled at the different time instant from the time instants for the set of data values to obtain at least one transformed value representing the physiological measure.08-16-2012
20120010482INSERTION SYSTEM - An insertion system for inserting a sensor into fatty tissue, comprising an insertion device and an insertion needle containing a sensor, wherein the insertion device comprises a holder for the insertion needle, and a piercing mechanism so as to move the holder, with the needle held by the same, in a feed direction for a puncture. The piercing mechanism changes the feed direction during the puncture so that, at the end of the puncture, an insertion needle held by the holder is oriented obliquely or perpendicular to the initial feed direction. Also provided are methods for controlling a needle moved by an insertion device.01-12-2012
20120010481Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant.01-12-2012
20120116189BATTERY - A battery comprises a carrier foil, with solid state battery elements spaced along the foil and mounted on opposite sides of the foil in pairs, with the battery elements of a pair mounted at the same position along the foil. The carrier foil is folded to define a meander pattern with battery element pairs that are adjacent each other along the foil arranged back to back.05-10-2012
20120065482DETERMINATION OF BLOOD PUMP SYSTEM PERFORMANCE AND SAMPLE DILUTION USING A PROPERTY OF FLUID BEING TRANSPORTED - The present invention provides methods and apparatuses related to measurement of analytes, including measurements of analytes in samples withdrawn from a patient.03-15-2012
20120016213BLOOD TEST STRIP AND AN INTRAVENOUS CATHETER SYSTEM - A blood test strip useful for venting a closed intravenous system and collecting a blood sample is described herein. The blood test strip includes a blood test strip, one or more vents, and a gripping member coupled to the proximal end of the blood test strip. The one or more vents are disposed between the distal and the proximal portions of the blood test strip.01-19-2012
20120016212Implantable Sensor Device - An implantable sensor device for capturing at least one physical, chemical, biological or physiological parameter in the body of a living being wearing the sensor device upon contact with the body fluid or tissue of the same, including a sensor housing, a sensor element that is accommodated in the sensor housing and has a capturing section, which has direct contact with the body fluid or the body tissue, or which internally adjoins a surface or opening section of the sensor housing that has contact with the body fluid or the body tissue, and a mechanically acting sensor cleaning device for cleaning the capturing section of the sensor element and/or the surface or opening section of the sensor housing adjoining the same.01-19-2012
20090137884METHODS AND APPARATUS FOR REPEATED ISCHEMIC CONDITIONING TREATMENT OF HYPERTENSION AND OTHER MEDICAL CONDITIONS - Methods for ischemic conditioning treatments of a chronic medical condition are provided. Baseline disease-related parameters of a patient with a chronic medical condition are measured. Ischemia is induced in the patient by occluding and releasing arterial flow in one or more extremities of the patient. Post-ischemia parameters in the patient are measured. The baseline and post-ischemia parameters are compared to provide an assessment of an ischemic conditioning treatment of a chronic medical condition. The repeated, scheduled delivery of ischemic conditioning provides a beneficial, therapeutic effect on the chronic medical condition. Also provided is a device for pulse oximetry during periods of absent or low pulsatile blood flow including an artificial pulse generator as well as the use of said device in assessment of ischemic conditioning.05-28-2009
20120022344INSERTION SYSTEM AND INSERTION DEVICE - An insertion system having a base unit for placing on the body of a patient and an insertion device that can be coupled to the base unit, wherein the insertion device comprises an insertion needle holder for holding an insertion needle and a drive mechanism for displacing the insertion needle holder in a pricking direction. According to the invention, the insertion device comprises a locking mechanism causing locking of the drive mechanism in an active state and being set to an inactive state in which the locking is released by coupling the insertion device to the base unit.01-26-2012
20120022346Analyte Sensor Transmitter Unit Configuration for a Data Monitoring and Management System - Method and system for providing analyte sensor alignment and retention mechanism for improved connectivity with a transmitter unit for electrical connection, and further including transmitter unit contact pins with metal components to improve electrical conductivity with the analyte sensor in an analyte monitoring and management system is provided.01-26-2012
20100191078ENERGY SUPPLY FOR FLUID DISPENSING DEVICE - Disclosed is a portable fluid dispensing device for infusing a fluid into the body of a user and/or for sensing an analyte within the body. The device includes at least one housing to retain a source of energy to energize the device, the source of energy comprising at least one electrochemical cell to produce electrical energy upon exposure of the cell to air, and a seal to prevent exposure of the at least one cell to air when the source of energy is not in use and to enable exposure of the at least one cell to air prior to energizing the device with the source of energy. The at least one housing includes an opening to provide access to the seal to enable actuation of the seal to control exposure of the at least one cell to air.07-29-2010
20120022345LANCET HAVING CAPILLARY CHANNEL AND STERILE PROTECTION ELEMENT AND METHOD FOR PRODUCING SUCH A LANCET - Lancets comprising a piercing element for puncturing the skin of a patient, a test region containing detection reagents for determining an analyte concentration of a body fluid sample, a capillary structure arranged in the piercing element for transporting a body fluid sample to the test region, and a sterile protection element, which encloses the tip of the piercing element. The capillary structure is blocked in a section surrounded by the sterile protection element. Also provided are methods for producing a lancet, comprising: producing a piercing element, which on the upper side has an upwardly open capillary structure; covering a section of the upper side of the piercing element and blocking the capillary channel in this section using a first material; covering a section of the underside using a second material; sterilizing the piercing element; and attaching a test region containing detection reagents to the piercing element.01-26-2012
20120059231DEVICE FOR PERFORMING AT LEAST ONE MEDICAL FUNCTION - A device for performing at least one medical function on a user is proposed. The device has at least one medical functional element that is designed to perform the medical function. The medical function is selected from a diagnostic, a therapeutic and a surgical function. The device has at least one evaluation and control part that comprises at least one actuation component for controlling the medical function. The evaluation and control part has at least one casing and at least one battery receptacle. The battery receptacle comprises at least one electrical energy reservoir, more particularly at least one battery. The battery receptacle is designed to be opened irreversibly by the user for removing the energy reservoir.03-08-2012
20120157801Adaptor for On-Body Analyte Monitoring System - An analyte monitoring system comprising: an on-body housing; an analyte sensor coupled to the housing; an electrical output interface disposed on an outer surface of the housing; and a removable adaptor coupled to the housing. In one embodiment, a portion of the analyte sensor extends from the housing for implantation into a patient's body. The electrical output interface is electrically coupled to the analyte sensor. The removable adaptor is mechanically coupled to the housing and electrically coupled to the electrical output interface. The removable adaptor serves as a data conduit between the analyte sensor and a remote device.06-21-2012
20080319285Apparatus and Method for Measuring Constituent Concentrations within a Biological Tissue Structure - Apparatus for minimally invasively measuring concentrations of constituents contained within a biological tissue structure includes a microwave energy source arranged generate a range of microwave frequencies, a first antenna coupled to the microwave energy source and arranged to transmit at least a portion of the microwave energy into the tissue structure, a second antenna arranged to receive at least a portion of the microwave energy transmitted through the tissue structure, a signal processor arranged to determine the resonant frequency of the received microwave energy, and a data processor arranged to provide an output of the concentration of constituents within the biological tissue structure according to the determined resonant frequency.12-25-2008
20090088612ACCESS DISCONNECT DETECTION - Techniques are disclosed for monitoring the flow of blood returning to a patient from an extracorporeal therapy machine, such as a hemodialysis machine or an apheresis machine. Blood returning from such a machine is pumped, typically by a peristaltic pump, which returns the blood in pulsed flow or pulses. This flow can be sensed by Doppler flow sensors or accelerometers as it returns to the patient. If the flow is interrupted by dislodgement of the venous access needle, or by leaking of blood from the needle, these sensors will detect significantly different flow or vibrations. A controller can then cease therapy, alert a caregiver, or sound an alarm.04-02-2009
20090082648METHOD AND APPARATUS FOR TREATING SKIN PRIOR TO BIOSENSOR INSERTION - Embodiments of the present invention provide a device and method for treating animal skin to produce tautness in the skin during the insertion of an analyte sensor. A device in accordance with embodiments of the present invention includes a housing that partially encloses a cavity and is adapted for mounting onto animal skin and a sensor insertion module adapted to insert an analyte sensor through animal skin.03-26-2009
20110184258Balloon Catheter Analyte Measurement Sensors and Methods for Using the Same - Balloon catheters, assemblies and systems and methods for using them for the continuous in vivo monitoring of one or more selected analytes or other physiological chemistries within a patient using an implantable analyte sensor associated with a balloon catheter are provided.07-28-2011
20120123229MODEL-BASED INFUSION SITE MONITOR - A medication delivery monitoring device is disclosed. The device includes a user interface configured to receive input information, and a sensor configured to measure a plurality of fluid state parameters of a fluid delivery channel through which the medication is delivered by a vascular access device (VAD) to an infusion site region of the patient. The device also includes a processor configured to determine a state of the infusion site region based on the plurality of measured fluid state parameters and the input information, and an output device configured to provide a communication regarding the state of the infusion site region. Methods and computer-readable mediums for monitoring medication delivery are also disclosed.05-17-2012
20120123228METHODS AND APPARATUS FOR TESTING DISRUPTION OF A VAGAL NERVE - Method and apparatus for disrupting a gastric vagal nerve in the gastroesophageal region and testing the function and disruption of the vagal nerve. In one example embodiment, a treatment device applies ultrasound at a high energy level, such as high intensity focused ultrasound, to a vagal nerve to disrupt it and then ultrasound at a lower energy level to another portion of the vagal nerve, preferably further from the stomach, so as to stimulate the vagal nerve. Alternative ways to test the function or disruption of the vagal nerve involve using PCP-GABA, a pancreatic polypeptide, pressure changes inside the stomach, the gastric mucusol pH, a dye agent in the stomach, and other tests.05-17-2012
20120123227Apparatus, Systems, and Methods Adapted to Transmit Analyte Data Having Common Electronic Architecture - Embodiments provide apparatus, systems, and methods adapted to communicate analyte data and/or related information. In a first aspect, the apparatus includes a transmitter/receiver unit which is configurable as either a transmitter or a receiver. The transmitter/receiver unit may be coupled to an on-body sensor and may be configured as a transmitter, or may be coupled to a management unit and may be configured as a receiver as part of a continuous analyte monitoring system. Analyte data communication systems and methods are provided, as are other aspects.05-17-2012
20090131769ANALYTE SENSOR - Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.05-21-2009
20090131768ANALYTE SENSOR - Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.05-21-2009
20120316409Hygiene Materials and Absorbents - A topical product including but not limited to a feminine hygiene product or incontinence shield which contains at least two kinds of particulate metals distributed throughout which, when in contact with moisture, form a galvanic current (virtually if not completely imperceptible to the user) that has antimicrobial effect on all pathogens. Galvanic current virtually or completely imperceptible to the user facilitates antimicrobial effect.12-13-2012
20120130207 MICRO-NEEDLE DEVICE AND APPARATUS AND A METHOD FOR APPLYING A MICRO-NEEDLE ELEMENT TO A SITE ON THE SKIN OF A SUBJECT - A micro-needle device (05-24-2012
20120316408INDICATORS FOR DETECTING THE PRESENCE OF METABOLIC BY-PRODUCTS FROM MICROORGANISMS - pH indicator compositions, solutions and suspensions and pH indicating food storage devices, medical devices and components thereof are provided for visually monitoring, detecting, and/or determining the presence of metabolic by-products from harmful or potentially harmful microorganisms. Also provided are methods of use and preparation of the pH indicator compositions, solutions and suspensions.12-13-2012
20100174158TRANSCUTANEOUS ANALYTE SENSOR - The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.07-08-2010
20100174157TRANSCUTANEOUS ANALYTE SENSOR - The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.07-08-2010
20100174156Method of Detecting and Measuring Hydration Imbalance - Hydration imbalance can adversely affect individuals who work in adverse environments or suffer from hydration related conditions. Rapid and continuous monitoring of at least one saliva component allows monitoring of an individual's hydration level. Interceptive preventive measures based on the detection and measurement of saliva osmolality/osmolarity at the early stages of hydration imbalance negates potential health hazards and death.07-08-2010
20120083677BLOOD ANALYZER - A blood analyzer capable of obtaining a blood analysis result instantaneously without sampling blood but rather applying a DC current to blood flowing through an artery and irradiating it with an ultrasonic wave is provided. It is equipped with a main measurement unit 04-05-2012
20100049013ANALYTE-TESTING DEVICE - A device adapted to determine an analyte concentration of a fluid sample using a test sensor. The device comprises a display adapted to display information to a user. The device further comprises at least one user-interface mechanism adapted to allow the user to interact with the device. The device further comprises a body portion including at least one opening formed therein, the at least one opening being of sufficient size to receive the test sensor. The device further comprises a memory adapted to store a plurality of stored analyte concentrations. The device further comprises a processing feature adapted to inhibit the stored analyte concentrations from being displayed on the display.02-25-2010
20100298671METHOD FOR ANALYZING ANALYTE IN TISSUE FLUID, ANALYZER FOR ANALYZING ANALYTE IN TISSUE FLUID, CARTRIDGE FOR ANALYZING ANALYTE IN TISSUE FLUID, AND KIT FOR ANALYZING ANALYTE IN TISSUE FLUID - A method for analyzing an analyte in tissue fluid is disclosed. The method comprises: placing a collecting member in contact with the skin of a subject, wherein the collecting member is configured to collect and retain tissue fluid containing the analyte from the subject; collecting tissue fluid from the subject into the collecting member; detaching the collecting member from the skin of the subject; causing the analyte in the tissue fluid collected by the collecting member to diffuse in a liquid by supplying the collecting member with the liquid; and detecting the analyte diffused in the liquid.11-25-2010
20100298670ELECTROLYTE MONITORING USING IMPLANTED CARDIAC RHYTHM MANAGEMENT DEVICE - A method for diagnosing an electrolyte level with a cardiac rhythm management device includes recording intra-cardiac electrograms from multiple sites. The method determines the electrolyte level based upon a comparative analysis of intra-cardiac electrograms recorded from at least two of the sites. The electrolyte level can be quantified based upon a general model, or a patient specific model.11-25-2010
20100305416NON-INVASIVE PRESSURED PROBING DEVICE - A non-invasive probing device wearable over a skin of a patient for monitoring the patient is provided. The probing device includes a physiological probe having a sensing interface, and a housing for housing the probe. The housing includes a body having a skin-side surface for lying next to the skin of the patient and a fixed or resilient protruding member fixedly or resiliently protruding from the skin-side surface. The protruding member houses the sensing interface. The device also includes attachment means for attaching the device to the skin of the patient. In the case of a resilient protruding member, the device may include a resilient mechanism for biasing the resilient protruding member against the body. Also in the case of a resilient protruding member, the device may include a protective cover for protecting the device against unwanted external influences.12-02-2010
20100010323Temperature-compensated in-vivo sensor - A reagent matrix composition disposed on an electrically conductive electrode to form an in-vivo sensor for a predefined analyte includes a first hydrogel layer containing an enzyme that is a substrate for the analyte adjacent the electrically conductive electrode and a composite membrane layer disposed onto the first hydrogel layer where the composite layer includes a membrane hydrogel containing a plurality of microspheres. The plurality of microspheres is made of a material having no or little permeability to the analyte and a substantially high permeability to oxygen.01-14-2010
20100010324SIGNAL PROCESSING FOR CONTINUOUS ANALYTE SENSOR - Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.01-14-2010
20120253145Systems and Methods for Transcutaneously Implanting Medical Devices - Systems and methods for transcutaneously implanting medical devices, such as in vivo analyte sensors, are provided. The systems and methods involve the use of introducers or inserters made of shape memory alloy (SMA) materials which are transitionable from one operative state or configuration to another operative state or configuration, wherein the transition from state to state enables the transcutaneous implantation and/or transcutaneous explantation of the medical device.10-04-2012
20120226115STACK MAGAZINE SYSTEM - A meter system for analyzing body fluids includes a supply magazine for storing a stack of test elements, a meter for analyzing fluid samples, and a transport system for transporting test elements from the supply magazine to the meter. The test element in one embodiment includes a lancet integrated test element that has a lancet coupled to a test strip. The transport system is configured to minimize damage to the test element. In one form, the transport system includes a shuttle that slides the top-most test element from the stack onto a connection portion of the meter. In another form, the transport system includes a drum that rotates to transport test elements from the supply magazine to a testing position and, once used, to a waste magazine for disposal. In a further form, the transport system includes a disc that rotates to transport the test elements.09-06-2012
20120259186Method and apparatus for an improved sample capture device - A body fluid sampling device is provided. A mesh (10-11-2012
20120190943Medical Device Inserters and Processes of Inserting and Using Medical Devices - An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices.07-26-2012
20120190942Medical Device Inserters and Processes of Inserting and Using Medical Devices - An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices.07-26-2012
20120190941Medical Device Inserters and Processes of Inserting and Using Medical Devices - An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices.07-26-2012
20090018413IMPLANTABLE MEDICAL DEVICE FOR DIAGNOSTIC SENSING - An implantable medical device is provided for use with an external detector to detect an analyte in vivo. In one embodiment, the device consisting essentially of a substrate; a plurality of discrete reservoirs located in the substrate, each reservoir having at least one opening; a reacting component contained in each reservoir; and at least one non-degradable barrier layer covering each reservoir opening, the barrier layer being permeable to an analyte to be detected, wherein the reacting component remains inside the reservoirs and can react with the analyte to be detected, and wherein the device is adapted for implantation into the body of a patient.01-15-2009
20090018412Medical unit with an apparatus for an examination of a patient and an associated method - The invention relates to a medical unit with an apparatus designed for the examination or treatment of a patient. The medical unit comprises at least one means designed for the collection or analysis of at least one substance exuded from the body of the patient during the course of a bodily process concomitantly to the examination or treatment of the patient with the apparatus.01-15-2009
20090018411Analyte Test Device - An analyte test device is constructed as an integrated, single-use, disposable cartridge which can be releasably installed into a compatible analyte test monitor. In use, the device can be used in conjunction with the monitor to lance the skin of a patient to create a blood sample and, in turn, calculate the concentration of a particular analyte in the expressed blood sample. In one embodiment, the device includes a base and a cover which are affixed together to create a test cartridge which has a substantially flat and low profile design. A lancet carrier is disposed between the base and the cover and includes a anchor fixedly mounted on the base and a lancet support member which is slidably mounted on the base, the anchor and the lancet support member being connected by a spring. A lancet is removably mounted on the lancet support member is disposed directly beneath an analyte test strip which secured to the underside of the cover. In another embodiment, the device includes a cylindrical housing with an open top end and an open bottom end. A spring biased lancet is slidably mounted within the cylindrical housing. An analyte test strip is fixedly mounted within the cylindrical housing and is disposed at an acute angle relative to the lancet.01-15-2009
20110004078BLOOD TESTING DEVICE - A blood testing device in which a blood sensor does not contaminate a piercing section when discarded. The blood testing device (01-06-2011
20110004077CONTAINER CONTAINING REFERENCE SOLUTION - The present disclosure provides a container containing reference solution for clinical chemistry, whereby the container includes a closure part-covered outlet at which reference solution can be removed by puncturing with a puncturing element. The disclosure further provides a wick that is soaked with the reference solution and arranged in the container to extend from the outlet and such that a majority of its length extends into an interior space of the container.01-06-2011
20120265034TISSUE-INTEGRATING SENSORS - Tissue-integrating biosensors, systems comprising these sensors and methods of using these sensors and systems for the detection of one or more analytes are provided.10-18-2012
20120265037ADVANCED ANALYTE SENSOR CALIBRATION AND ERROR DETECTION - Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.10-18-2012
20120265033EVALUATING DOSING FROM AN IMPLANTABLE INFUSION DEVICE - A method for evaluating dosing from an implanted infusion system that includes receiving input regarding the identity of a therapeutic agent into an external device. The method further includes displaying on the external device a predetermined set of symptoms associated with the therapeutic agent; receiving input into the external device regarding with which of the symptoms the patient presents; and determining whether the therapeutic agent is being delivered, or has been delivered, at an appropriate dose based on the input identity of the therapeutic agent and the input symptoms.10-18-2012
20120265036ADVANCED ANALYTE SENSOR CALIBRATION AND ERROR DETECTION - Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.10-18-2012
20120265035ADVANCED ANALYTE SENSOR CALIBRATION AND ERROR DETECTION - Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.10-18-2012
20110046458DEVICE FOR DETECTING A MEDICAL CONDITION OR DISEASE - The invention relates to a capsule or chip or sensor comprising a marker/detector and signalling device/method associated with the development of a medical condition/disease and to its use. This In Situ Lab On a Chip Signalling device (ISLOGS device) is used for detecting a medical condition/disease in situ or in vivo (inside the body), for example by swallowing it for testing in the digestive tract or by putting it into the vagina, mouth or nose. All reactions takes place in the body and when the test result is positive the device will notify the subject by colorizing the tested body fluid or biomaterial (for example faeces, urine or saliva) or the device itself. The detection is made outside of the body when the biomaterial or ISLOCS device has left the body.02-24-2011
20110046456Assembly Comprising Inserter, Cannula Part and Base Part - The invention relates to an assembly comprising—an inserter (02-24-2011
20110046454INJECTION APPARATUS - An injection apparatus (02-24-2011
20110046453TEST STRIP WITH A SHAPED TIP FOR SKIN STRAIGHTENING - The test strip stabilizes skin prior to incision by a lancet tip. The innovative test strip includes a pair of skin contacting tabs that apply pressure linearly to the skin to stretch the skin taut. Beneficially an incision by a lancet tip to an accurate depth can be formed on the taut skin. Moreover, pressure from the tabs is applied linearly to the skin which results in a higher ratio of pressure to surface that can be reached as compared to applying pressure laminarily to skin. Some manufacturing techniques of the skin contacting tabs include cutting or stamping through all of the layers and test area of the test strip to form these tabs. These techniques increase the manufacturing efficiency and cost savings associated with test strips and integrated lancet testing devices. Contamination from other sampling events is eliminated since the test strips are disposed of after each use.02-24-2011
20120271123Integrated lancing device - A lancing device is provided that has a housing with a length greater than a width. Electronics are positioned in an interior of the housing. A test strip aperture is in the housing and is adapted to receive a body fluid test strip. A lancet aperture is positioned in line with the test strip aperture.10-25-2012
20120271126Apparatus for obtaining and analyzing a blood sample with a lancet coupling mechanism - An apparatus for obtaining and analyzing a blood sample is presented. The apparatus comprises an integrated drive unit having a common drive source and a drive force transmission gearing that couples a lancet drive, a device for advancing a magazine, and a sample transfer device to the drive source. A tensioning rotor and a drive rotor are mounted so that they are rotatable coaxially to one another. A first cam control converts the rotation of the drive rotor into a radial forward and reverse movement of a drive rod. A second cam control converts the rotational movement of the tensioning rotor into a linear movement of a link slide. A switching link moved by the link slide rotates the magazine an additional step. A third cam control converts the rotational movement of the tensioning rotor into a linear movement of a pressure tappet perpendicular to the piercing axis.10-25-2012
20120271125DEVICES AND METHODS FOR DELIVERY AND/OR WITHDRAWAL OF FLUIDS AND PRESERVATION OF WITHDRAWN FLUIDS - The present invention generally relates to systems and methods for delivering and/or withdrawing a substance or substances such as blood or interstitial fluid, from subjects, e.g., from the skin and/or from beneath the skin. In one aspect, the present invention is generally directed to devices and methods for withdrawing or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a fluid transporter (for example, one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some cases, the device may be self-contained, and in certain instances, the device can be applied to the skin, and activated to withdraw blood from the subject. The device, or a portion thereof, may then be processed to determine the blood and/or an analyte within the blood, alone or with an external apparatus.10-25-2012
20120271124Thrombospondin Fragments and Uses Thereof In Clinical Assays for Cancer and Generation of Antibodies and Other Binding Agents - The invention relates to thrombospondin fragments found in plasma, their use or use of portions thereof in diagnostic methods, as method calibrators, method indicators, and as immunogens, and as analytes for methods with substantial clinical utility; and their detection in plasma or other bodily fluids for purpose of diagnostic methods, especially for cancer.10-25-2012
20120323091METHODS AND APPARATUS FOR GUIDING MEDICAL CARE BASED ON DETECTED GASTRIC FUNCTION - Embodiments relate to guiding medical care based on detected gastric function. For example, gastric acid stimulant or suppressant is administered, and then a change in the gastric juice H+ concentration is measured. This change is compared to a guidance H+ concentration differential indicative of relatively healthy gastric function. Medical care is guided based on a relatively healthy gastric function if the measured H+ concentration differential is equal to or exceeds the guidance H+ concentration differential, while medical care is guided based on a relatively unhealthy gastric function if the measured H+ concentration differential is less than the guidance H+ concentration differential. Disclosed embodiments implementing this procedure include, but are not limited to, methods, apparatus, processors, computer programs, and computer-readable mediums.12-20-2012
20120277552CHRONIC pH OR ELECTROLYTE MONITORING - Methods include monitoring blood pH or electrolyte levels and setting initial fluid parameters, such as dialysate fluid parameters or replacement fluid parameters, for a blood fluid removal session based the monitored data. Blood fluid removal systems may employ sensors that monitor blood pH or electrolyte levels to adjust the fluid parameters during a blood fluid removal session.11-01-2012
20110245635PRESSURE REDUCTION MECHANISM, PUNCTURE DEVICE, BLOOD ANALYSIS DEVICE, AND SENSOR MOUNTING MECHANISM - Provided are a decompression mechanism capable of performing a desired pressure reduction by simple operation and having improved operability, a puncture device, a blood analysis device, and a sensor mounting mechanism. A needle puncturing device (10-06-2011
20120088990MEDICAL SENSOR SYSTEM - A medical sensor system (04-12-2012
20120088989Management Method And System For Implementation, Execution, Data Collection, and Data Analysis of A Structured Collection Procedure Which Runs On A Collection Device - In one embodiment, a method of performing a structured collection protocol by utilizing a collection device comprising a processor may include collecting at least one sample using the collection device. The at least one sample can be associated with biomarker data. A classification can be associated with the at least one sample via the processor. The classification can be based upon an intended use of the at least one sample. Compliance with an adherence criteria for the at least one sample can be determined via the processor. When the at least one sample is not compliant with the adherence criteria, an adherence event can be associated with the at least one sample, and the processor can perform at least one additional task that is based upon the classification associated with the at least one sample.04-12-2012
20120330115ANALYTE MONITORING SYSTEMS AND METHODS - A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.12-27-2012
20110319729MEDICAL DEVICE INSERTERS AND PROCESSES OF INSERTING AND USING MEDICAL DEVICES - An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices.12-29-2011
20110319728BLOOD PARAMETER SENSOR AND FLOW CONTROL SYSTEM, METHOD AND COMPUTER PROGRAM PRODUCT - A system is provided for sensing a blood parameter, such as an analyte, in a patient's vasculature. The system includes a vascular access device, a parameter sensor, a pressure sensor and a flow control device. The vascular access device supports the parameter sensor within the vasculature of the patient and includes an internal passageway for drawing samples onto and calibrating the parameter sensor. The pressure sensor is within the internal passageway. The flow control device modulates sample draw, calibration and flushing fluid flows to prevent or remove clots based on communication with the pressure sensor. Advantageously, the dynamic, adaptive modulation of flow reduces flushing and other cycle times while at the same time improving clot flushing. As another advantage, this enables reduction or elimination of the use of heparin and other anticoagulant components in the solution supplied for flushing and/or calibration.12-29-2011
20120289795Self-Flowing Measuring System - The invention relates to a method and arrangement for continuously measuring substances in a pressurised body fluid. A probe (11-15-2012
20120150000Non-Invasive Monitoring Device - The invention concerns a device for non invasive monitoring of the concentration of a constituent of a human or animal bloodstream. In the preferred example the device comprises drive circuitry (06-14-2012
20120149999Tissue penetration device - A sampling module includes a module body portion with a lancet channel, a lancet slidably disposed within the lancet channel. A cover sheet is disposed over the lancet and a lancet channel that captures the lancet shaft in the lancet channel, and a sample reservoir for collection of a sample obtained by lancing a patient with the lancet.06-14-2012
20080228048Physiological Sensors with Telemonitor and Notification Systems - Systems and methods are provided which enable communications to be initiated locally relative to an individual's developing physiological condition and remotely as the condition requires. Physiological sensors and associated medical delivery systems can be coupled to a unit wearable by an individual which can provide various audible or visual outputs and one or more manual inputs indicative of the individual's condition. A global positioning unit can be incorporated so that condition information as well as location information can automatically be provided, wirelessly, to a remote monitoring system for follow up as needed.09-18-2008
20130172696MEDICAL HAND-HELD MEASURING DEVICE WITH EXCHANGEABLE PROBE - The invention relates to a medical hand-held measuring device for measuring the pH value and/or the temperature of wounds, including a housing (07-04-2013
20130178722Sharp Tip Carbon Nanotube Microneedle Devices and Their Fabrication - Carbon nanotube needles and needle arrays are described in which the precursor pillars are etched by oxygen plasma treatment to provide tapered and/or sharp-tip needles. Processes, products by process, and devices incorporating the sharp-tip needles are further described.07-11-2013
20080221407Method for evaluating skin hydration and fluid compartmentalization - There is provided a system and method for evaluating skin hydration and fluid compartmentalization. The system includes a microneedle array configured to extract fluid from an interstitial space and a pressure sensor configured to measure a pressure differential between the interstitial space and ambient pressure during extraction of the fluid. A processor coupled to the pressure sensor is configured to compute a hydration index based on the pressure differential. A display coupled to the processor is configured to display the hydration index.09-11-2008
20120253144SENSOR - An embeddable sensor includes a sensor body, a detector housed in the sensor body, and a retaining mechanism mounted on a side surface of the sensor body. The retaining mechanism includes at least one projection on the side surface of the sensor body. The projection is of a V shape which is progressively wider and higher from a distal end toward a proximal end of the sensor body. The projection is made of a material whose hardness is lowered upon elapse of a certain period of time within a living body. When the embeddable sensor is inserted in the living body, the projection retains the embeddable sensor within the living body. Upon elapse of the certain period of time within the living body, the projection loses its capability to retain the embeddable sensor within the living body.10-04-2012
20100030037BLOOD INSPECTION DEVICE - A blood inspection device capable of separately discharging a sensor and a filter by using single discharge means. The blood inspection device has a housing (02-04-2010
20130172695Medical Skin Mountable Device and System - A medical device is provided comprising a transcutaneous device unit and a process unit. The transcutaneous device unit may comprise a transcutaneous device for transporting a fluid through a skin portion of a subject, and a mounting surface adapted for application to the skin of the subject. The process unit may comprise a reservoir adapted to contain a fluid drug, the reservoir comprising an outlet means allowing the transcutaneous device to be arranged in fluid communication with an interior of the reservoir, and an expelling assembly for expelling a fluid drug out of the reservoir and through the skin of the subject via the transcutaneous device. The transcutaneous device unit and the process unit further comprise coupling means allowing the reservoir unit to be secured to the transcutaneous device unit in the situation of use. By this arrangement a two-unit system is provided which can be used in a convenient and cost-effective manner.07-04-2013
20130096399METHODS AND DEVICES FOR DETECTING BOWEL PERFORATION - The present disclosure relates to methods and devices to detect perforation of the bowel, for example, resulting from surgical procedures, such as laparoscopy, diagnostic procedures, such as colonoscopy, medical conditions, such as diverticulitis, and trauma. The present disclosure also relates to filtration systems and electrical connector assemblies for use in the methods and devices.04-18-2013
20130102860Drains for Use in Medical Applications and Methods of Using the Same - A drain for use in medical applications may include an elongated conduit configured to be implanted in a body cavity, wherein the conduit has a proximal end and a distal end. The conduit may include at least one channel configured to drain fluid from the body cavity and at least one lumen extending from the proximal end to the distal end of the conduit. The lumen may be at least partially surrounded by the at least one channel and may be separated from the at least one channel by a wall. At least one hole in the wall may be configured to provide fluid communication between the lumen and the at least one channel.04-25-2013
20130131468MEDICAL DEVICE COMPRISING A MULTIPART HOUSING - A medical device for carrying out at least one medical function, comprising at least one element that can be at least partially inserted into a body tissue of a user and further comprising at least one housing that can be placed on a skin surface of the user. The housing has a multipart design and comprises at least one functional component. The functional component can be connected to the insertable element. The housing further comprises at least one protective component. The protective component is designed to at least partially enclose the functional component. The protective component can be connected to the functional component, particularly after insertion of the insertable element.05-23-2013
20130131467METHOD AND DEVICE FOR PUNCTURE OF INSERTION NEEDLE INTO SUBCUTANEOUS FATTY TISSUE - An insertion device with an underside for placing on the skin of a patient, which has a recess for an insertion needle. The insertion device has means for forming a skin surface rising like a step or slope and facing towards the recess, preferably bearing on the recess. The means for forming the step or slope may include first and second pressure areas for pressing the skin with the recess for the needle located between the first and second pressure areas. The device may be configured whereby a downwardly extending cutting plane, in which the insertion needle lies, intersects the first pressure area in a first line and the second pressure area in a second line, and wherein the first line in the vicinity of the recess extends at a greater height than the second line. At least one of the two pressure areas may be a strip.05-23-2013
20130144133DEVICES WITH SELECTIVELY PERMEABLE BARRIERS - Devices having selectively permeable barriers are provided with a substrate, a first layer overlaying at least a portion of the substrate, and a second layer overlaying at least a portion of the first layer. The first layer has at least one first pore and the second layer has at least one second pore. At least a portion of the first and/or second layers are movable with respect to each other between an open condition and a closed condition in response to a change in an environmental factor. In the open condition, the first and second pores are substantially aligned to allow fluid communication between the substrate and the outside environment. In the closed condition, the first and second pores are substantially misaligned to prevent fluid communication between the substrate and the outside environment.06-06-2013
20130144134NMR SYSTEMS FOR IN VIVO DETECTION OF ANALYTES - This invention relates generally to NMR systems for in vivo detection of analytes. More particularly, in certain embodiments, the invention relates to systems in which superparamagnetic nanoparticles are exposed to a magnetic field and radio frequency (RF) excitation at or near the Larmor frequency, such that the aggregation and/or disaggregation of the nanoparticles caused by the presence and/or concentration of a given analyte in a biological fluid is detected in vivo from a monitored RF echo response.06-06-2013
20130144135METHOD AND APPARATUS FOR THREE DIMENSIONAL RECONSTRUCTION OF A JOINT USING ULTRASOUND - A method of generating a 3-D patient-specific musculoskeletal model. The method includes acquiring a plurality of raw radiofrequency (“RF”) signals from an A-mode ultrasound scan of the bone while tracking the acquiring in 3D space. The bone contours are isolated in each of the plurality of RF signals and transformed into a point cloud. A 3-D model of the bone is then optimized with respect to the point cloud. The 3-D patient-specific musculoskeletal model may include a model of a bone, a model of a joint, a model of cartilage, or a combination thereof.06-06-2013
20080200779Implant Sensor and Control - An implant includes a humidity sensor for generating a signal indicative of humidity within the implant. A controller within the implant receives the signal indicative of humidity, and controls the implant based on the signal indicative of humidity.08-21-2008
20110275912Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant.11-10-2011
20120259185Systems, Methods and Devices for Adjusting the Insertion Depth of a Cannula Associated with a Portable Therapeutic Device - Systems, methods and devices are described herein for adjusting the insertion depth of a cannula associated with a portable therapeutic device within the body of a patient. The systems may include a mounting unit securable to the skin of the patient and having a mounting base and a well defining a passageway through the mounting base and a cannula unit including a cannula subcutaneously insertable through the well of the mounting unit. The well may have an adjustable height and/or adjustable anchoring mechanisms that allow for varying and customized insertion depths of the cannula within the body of the patient.10-11-2012
20100317935TEST MEDIA CASSETTE FOR BODILY FLUID TESTING DEVICE - A bodily fluid sampling device includes a piercing device and a sensor enclosed in a housing. A cassette, which contains test media, is positioned proximal to the sensor so that the sensor is able to analyze a bodily fluid sample collected on the test media. The cassette includes a supply portion from which unused test media is supplied and a storage portion in which contaminated test media is stored after exposure to the bodily fluid. The cassette is adapted to collect a series of bodily fluid samples without requiring disposal of the test media.12-16-2010
20120283528TAPE MAGAZINE WITH REWIND LOCK AND INTEGRATED TAPE RELEASE - A replaceable magazine for use in an analytic test instrument a plurality of analytic aids on a carrier tape. The analytic aids can be made available in an application position of the magazine by means of the carrier tape. The magazine has a supply reel for holding regions of the carrier tape with unused analytic aids and a take-up reel for holding regions of the carrier tape with used-up analytic aids. The carrier tape can be moved in a spooling direction from the supply reel to the take-up reel. The magazine has a rewind lock of the take-up reel. The magazine has a tape release device, which is configured to make available a take-up reel tape reserve of the carrier tape on the side of the application position facing the take-up reel. The take-up reel tape reserve enables a lifting movement of an analytic aid situated in the application position.11-08-2012
20130184543Systems and Methods for Obtaining Analytes From a Body - A method may include collecting at least one analyte from within a body, ejecting the collected at least one analyte from the body through at least one dermal layer of the body, and receiving the ejected at least one analyte outside the body. A system may include a means for collecting at least one analyte from within a body, a means for ejecting the collected at least one analyte from the body through at least one dermal layer of the body, and a means for receiving the ejected at least one analyte outside the body.07-18-2013
20130184542Method and System for Providing an Integrated Analyte Sensor Insertion Device and Data Processing Unit - Method and apparatus for providing an integrated analyte sensor and data processing unit assembly is provided.07-18-2013
20130184541INFUSION SET COMPONENT WITH MODULAR FLUID CHANNEL ELEMENT - An infusion set component of a fluid infusion device and/or a fluid infusion port component for delivery of fluid to a patient is compatible with a cooperating fluid channel module. The fluid channel module includes a body section having coupling features to mate with a base of the component. The fluid channel module also includes an interior fluid flow channel formed within the body section to receive fluid from the fluid infusion device and/or from a syringe or pen delivery device. The fluid channel module also includes a conduit having a first end in fluid communication with the interior fluid flow channel, and having a second end to deliver the fluid to the patient.07-18-2013
20130190578Low pain penetrating member - Reducing the volume or drag on skin or sharpness of the penetrating member entering the wound during the cutting process will reduce the pain associated with lancing, and result in less power desired for retraction of the penetrating member from the skin. A variety of other penetrating member configuration as shown in the application.07-25-2013
20120029325Device for determining the characteristics of peritoneal membrane - Device for determining the characteristics of peritoneal membrane comprising means for measuring glucose in the fluid drainage and a processing unit comprising means for determining the characteristics of the membrane as a function of that rate of glucose measured at different times. The invention also relates to a method for determining the characteristics of peritoneal membrane including the consideration of glucose measured at different moments in the liquid drainage.02-02-2012
20120029324THERAPY PREDICTION AND OPTIMIZATION FOR RENAL FAILURE BLOOD THERAPY, ESPECIALLY HOME HEMODIALYSIS - A method of predicting serum phosphorus concentrations in a patient during hemodialysis includes measuring serum phosphorus concentrations of the patient over a hemodialysis treatment session time and an ultrafiltration rate calculated by a difference between pre- and post-dialytic body weight of the patient during an initial hemodialysis treatment session divided by a total treatment time of the treatment session and estimating a phosphorous mobilization clearance and a pre-dialysis distribution volume of phosphorus for the patient. Serum phosphorus concentrations of the patient can then be predicted at any time during any hemodialysis treatment session with the estimated phosphorous mobilization clearance and pre-dialysis distribution volume of phosphorus of the patient.02-02-2012
20130197325ANTI-COAGULANT INFUSION FLUID SOURCE - Methods and systems for preventing or eliminating blood coagulation or thrombus during use of an intravenous anti-thrombotic sensor are disclosed. The method further comprises for providing antimicrobial into the infusion fluid source. An anti-thrombotic sensor is also disclosed that comprises a coating of a complex of a non-heparin anti-thrombotic agent and an alkylbenzyldimethyl ammonium cationic salt.08-01-2013
20120071737Breath Delivery System and Method - Some embodiments of the invention provide a mouthpiece for use with an electronic analyzer for breath analyte detection in an individual. The mouthpiece includes a biosensor and a hydration system. The biosensor includes a chemically active area where a chemical reaction takes place and the hydration system delivers a liquid to the chemically active area of the biosensor to at least one of enhance, enable, and facilitate the chemical reaction. The mouthpiece further includes hardware to transmit breath analyte data.03-22-2012
20120071736Medical Device With a Fitting Having A Gas Venting Position - A blood parameter measurement cassette or other device is configured to control incidental liquid discharged during the device's calibration process. The cassette includes optical sensors which are chemically responsive to blood constituents and require calibration with a blood parameter monitoring device prior to use in a medical procedure. During the calibration process, an incidental amount of a liquid may be expelled from the cassette. The present invention is directed towards controlling the expelled liquid by absorbing it using an absorbent material disposed on the exterior of the cassette's main body. The absorbent material thereby prevents the liquid from causing detrimental effects to the monitoring and calibration equipment used in conjunction with the cassette. The scope includes additional embodiments wherein the inventive concept is applied to other fluid-handling medical devices that require venting of gases.03-22-2012
20130211211SAMPLING APPARATUS - There is provided a chip-type sampling apparatus to be attached so that a sampling side of the sampling apparatus faces the skin, the apparatus including a porous adsorption layer that faces the sampling side and has a pore diameter in a range of 0.1 to 1000 nm. One example of the adsorption layer includes at least three porous layers with different central pore diameters that are laminated from the sampling side in descending order of the central pore diameters. The sampling apparatus should preferably also include a layer that sucks air through the adsorption layer.08-15-2013

Patent applications in class Measuring or detecting nonradioactive constituent of body liquid by means placed against or in body throughout test

Patent applications in all subclasses Measuring or detecting nonradioactive constituent of body liquid by means placed against or in body throughout test