Class / Patent application number | Description | Number of patent applications / Date published |
568816000 | Plural alicyclic rings containing | 29 |
20100081850 | ISOLATION AND PURIFICATION OF CARTENOIDS FROM MARIGOLD FLOWERS - A process for isolation of carotenoids crystals having lutein and zeaxanthin in a weight ratio of about 10:1, 5:1 or 1:1. The process comprises contacting a plant source rich in lutein with hexane and extracting at a temperature of about 40° C. to 60° C. to obtain an oleoresin rich in lutein; contacting a plant source rich in zeaxanthin with hexane and extracting at a temperature of about 40° C. to 60° C. to obtain an oleoresin rich in zeaxanthin. The oleoresin rich in lutein and the oleoresin rich in zeaxanthin are mixed separately in a ratios ranging from about 80:20(w/w) to 90:10(w/w) or about 70:30(w/w) to 30:70(w/w) or about 10:90(w/w) to 20:80(w/w) and homogenized to obtain a mixed oleoresin. The mixed oleoresin is hydrolyzed with an alcoholic alkali at a temperature of about 70° C. to 80° C. to obtain a reaction mixture. The carotenoids crystals are precipitated by adding hot water to the reaction mixture to form a precipitate. Carotenoids crystals having lutein and zeaxanthin in a ratio of about 10:1 or 5:1 or 1:1 respectively are obtained by filtering, washing and drying the precipitate. | 04-01-2010 |
20100121112 | Method for the purification of carotenoids from plant extracts and the products so obtained - A novel process for the preparation of highly purified carotenoids from plant extracts, especially the marigold flower extracts, is disclosed. The process includes the formation, isolation and purification of carotenoids, primarily lutein and zeaxanthin, at lower temperatures with the use of at least a polar solvent and at least a non-polar solvent. The highly purified carotenoids so obtained are useful for human consumption, such as nutritional supplements and pharmaceuticals. | 05-13-2010 |
20100204523 | METHOD OF PREVENTING DISCOLORATION OF CAROTENOID PIGMENT AND CONTAINER USED THEREFOR - The method includes storing a carotenoid pigment in a container that has an average spectral transmittance of 0.01 to 45.0% at a wavelength of 535 to 695 nm. | 08-12-2010 |
20100240933 | Lutein Extraction from Ozone-Treated Plant Sources - The use of ozonation has been discovered to increase the lutein extraction from aflatoxin-free corn and for some batches of alfalfa. In addition, the ozonation will substantially decrease any aflatoxin in the plant source. The structure of lutein as indicated by HPLC elution profile and the function of lutein using an antimutagenic activity was shown not to be affected by the ozonation. | 09-23-2010 |
20100280286 | Process For The Preparation of Beta and Alpha Cryptoxanthin - The present invention relates to a process for converting lutein and/or lutein esters to (3R)-β-cryptoxanthin and (3R,6′R)-α-cryptoxanthin, suitable for human consumption as dietary supplements, by employing safe and environmentally friendly reagents. (3R)-β-Cryptoxanthin and (3R,6′R)-α-cryptoxanthin are two rare food carotenoids that are not commercially available and the former exhibits vitamin A activity. In the first synthetic step, commercially available lutein and/or lutein esters are transformed into a mixture of dehydration products of lutein (anhydroluteins) in the presence of a catalytic amount of an acid. The resulting anhydroluteins are then converted to (3R)-β-cryptoxanthin (major product) and (3R,6′R)-α-cryptoxanthin (minor product) by heterogeneous catalytic hydrogenation employing transition elements of group VIII (Pt, Pd, Rh supported on alumina or carbon) in a variety of organic solvents under atmospheric pressure of hydrogen and at temperatures ranging from −15° C. to 40° C. Among these catalysts, Pt supported on alumina at 40° C. in ethyl acetate provides the best yield of (3R)-β-cryptoxanthin and (3R,6′R)-α-cryptoxanthin. Several homogeneous catalysts can also promote the regioselective hydrogenation of anhydroluteins to a mixture of (3R)-β-cryptoxanthin and (3R,6′R)-α-cryptoxanthin in low to moderate yields. The catalysts may be transition metal complexes such as palladium acetylacetonate, Rh(Ph | 11-04-2010 |
20100305366 | Lutein Extraction Processes - A lutein extraction process comprises pulverizing marigold, adding organic solvent in the former, then placing into an ultrasonic extraction vessel for ultrasonic extraction, filtering the extracted solution, and recovering to obtain a filtrate containing lutein ester; adding an alkaline solution that is 2 times of the filtrate volume in the filtrate recovered in the above step, and performing saponification on the lutein ester in the filtrate at 50-70° C.; washing the resultant after saponification with deionized water until lutein crystallization occurs, centrifuging the solution containing the lutein crystals to obtain crude crystals of lutein; subjecting the crude crystals of lutein to recrystallization; washing the lutein crystals obtained by recrystallization, and drying to obtain lutein crystal product. The ultrasonic extraction method in the present invention utilizes ultrasonic wave-induced intensive vibration, high acceleration, intensive cavitation effect, and stirring action to accelerate entrance of lutein into solvent, so as to increase extraction rate of effective components and shorten the extraction time. | 12-02-2010 |
20110065965 | PROCESSES AND METHODS FOR EXTRACTION AND PURIFICATION OF LUTEIN FROM MARIGOLD ESTERS - A process is disclosed for simultaneously extracting, saponifying, and isolating lutein without the use of harmful organic solvents. In one embodiment the method includes (a) dispersing Marigold oleoresin in an alkane hydrocarbon alkanol solution, (b) adding a potassium hydroxide to the Marigold oleoresin and alkane hydrocarbon alkanol solution to form a homogenous solution of Marigold oleoresin, (c) refluxing the homogeneous solution until ester hydrolysis of the Marigold oleoresin is completed, (d) cooling the homogeneous solution and allowing it to settle until lutein crystals are formed and (e) washing the lutein crystals with methanol-hexane solution to separate and filter them from the solvents. | 03-17-2011 |
20120296126 | Preparing Method for Xanthophyll Crystals with Higher Content of Zeaxanthin from Plant Oleoresin - The invention makes public a preparing method for xanthophyll crystals with higher content of zeaxanthin from plant oleoresin. The current methods generally are to get quite pure crystal forms of xanthophyll or zeaxanthin, and they refer to several separation steps. The invention mixes the xanthophyll diester-containing plant oleoresins and food grade alcohol solvents to form even solution, and then soap-dissolve the solution under an alkaline environment; then replenish organic solvents and emulsifiers into the reaction solution and drop some alkali solution into the solution to make partial xanthophyll crystals be transformed to be zeaxanthin through epimerization reaction; after the reaction is finished, add the mixed solvents of alcohol solvent and water to separate out the crystals; use the method of centrifugation or filtration to get the crystals; wash the crystals several times with the mixed solution of deionized water and alcohols to remove the impurities among the crystals; recrystallize the gained crystals with absolute ethyl alcohol, and then dry the crystals to get the products. The invention can gain mixture crystals that contain xanthophyll and zeaxanthin at one time in quite high collection rate, and it is convenient for the followed product application. | 11-22-2012 |
20130030218 | METHOD FOR PRODUCING ZEAXANTHIN BY FERMENTATION - A method for microbiologically producing zeaxanthin at high concentration and low cost while suppressing production of gluconic acid is presented. Specifically, a method for producing carotenoids containing zeaxanthin by culturing a bacterium producing carotenoids containing zeaxanthin in a medium containing biotin is provided. | 01-31-2013 |
20130066117 | PROCESS FOR ISOLATION AND PURIFICATION OF CAROTENOIDS - The present invention discloses a novel saponification process for the isolation and purification of highly pure carotenoids from different carotenoid rich oleoresin derived from plants and microorganisms without the use of toxic chemicals and hazardous solvents. The hydrolysis is carried out by treating the carotenoid rich oleoresin with a novel mixture of a Fatty alcohol, alkali and a fatty acid without the use of any other solvents. Further the invention explains a process of stabilising the carotenoids from getting degraded due to high temperature and exposure time during the saponification process. Further the invention discloses an economically viable process of isolating high pure carotenoids with higher yield. | 03-14-2013 |
20140200374 | METHOD OF EXTRACTING LUTEIN/XANTHOPHYLLS FROM NATURAL MATERIALS AND HIGHLY PURIFIED LUTEIN/XANTHOPHYLLS OBTAINED FROM THE METHOD THEREOF - The present invention provides the new method for extracting lutein from natural materials wherein the said method comprises of modification of natural lutein ester in the natural materials to free lutein and/or low molecular weight lutein ester, extraction of the said natural materials with supercritical fluid at the optimal conditions. The said method yields high amount of crude lutein with high purity due to the mild condition used for extraction. Therefore, no degradation of the desired product is occurred. The crude lutein can be further purified with chromatography in order to obtain the highly purified lutein. The method according to this invention can be applied to the extraction of xanthophylls or others beside lutein. | 07-17-2014 |
20140303406 | Process for Preparing Xanthophyll Crystal - Disclosed a process for preparing a xanthophyll crystal, comprising: dissolving the plant extract containing a xanthophyll ester in n-hexane, then filtering the mixture; adding acetone to the filtrate, filtering and collecting a filter cake; mixing the filter cake with soybean oil and ethanol uniformly; saponifying the mixed solution with alkaline aqueous solution; then adding an acidic solution thereto until the mixed solution becomes acidic, concentrating under reduced pressure to obtain a pasty substance; adding n-hexane to the pasty saponified product, standing still and then conducting a solid-liquid separation; washing the resulting solid substance with deionized water; adding a mixed solvent to the washed solid substance, dissolving it with stirring; and then adding n-hexane thereto and standing still to recrystallize. According to the application, organic solvents are used to treat the plant extract and remove non-xanthophyll ester compounds in order to improve the efficiency of the saponification reaction; the saponified solution is concentrated under acidic condition at reduced pressure, then extracted with an organic solvent for saving water; purifying a xanthophyll crystal with a mixed solvent in order to significantly increase the purity of a xanthophyll crystal and proportion of trans-xanthophyll. | 10-09-2014 |
20150099901 | METHOD FOR PRODUCING HYDROGENATED BIPHENOL - Provided is a method for efficiently producing high-purity hydrogenated biphenol based on a simple method that can be industrially utilized using easily-available biphenol as a starting material. | 04-09-2015 |
20160122268 | PROCESS FOR SIMULTANEOUS EXTRACTION AND SEPARATION OF ESTERIFIED AND UNESTERIFIED MONOHYDROXYCAROTENOIDS - The present invention is in the field of organic and natural product chemistry. The present invention relates to an efficient process for purification, simultaneous extraction, and separation of monohydroxycarotenoids from dihydroxycarotenoids in various natural products or in synthetic mixtures. Similarly, the process can also be applied to the simultaneous extraction, saponification, and separation of esterified mono- and dihydroxycarotenoids in natural products and their oleoresins or in their synthetic mixtures. Therefore, esterified and unesterified monohydroxycarotenoids such as (3R)-β-cryptoxanthin and (3R,6′R)-α-cryptoxanthin can be efficiently separated from their corresponding dihydroxycarotenoids such as (3R,3′R,6′R)-lutein and (3R,3′R)-zeaxanthin that are found in various plants or in synthetic mixtures. | 05-05-2016 |
568817000 | Polycyclo ring system | 15 |
20090030242 | POLYMER OF POLYCARBONATE DIOL HAVING AN ALICYCLIC STRUCTURE AND PRODUCTION PROCESS THEREOF - The invention relates to a polycarbonate diol, comprising an organic residue derived from a diol component represented by formula (1), | 01-29-2009 |
20090253943 | BIRCH BARK PELLETIZATION AND METHODS FOR OBTAINING NATURAL PRODUCTS FROM BIRCH BARK PELLETS - The present invention provides birch bark pellets that include outer birch bark. The present invention also provides methods of manufacturing birch bark pellets from outer birch bark. The present invention also provides methods for obtaining a natural product from birch bark pellets. The birch bark pellets are manufactured from outer birch bark that includes relatively low amounts of inner birch bark and wood. The birch bark pellets meet the requirement for extraction, to obtain e.g., betulin and/or lupeol from the pellets. | 10-08-2009 |
20110021848 | WICKEROL AND METHOD FOR PRODUCING THE SAME - The present invention includes wickerol and a method for producing the wickerol. In the method for producing the wickerol, | 01-27-2011 |
20120088939 | HYALURONIC ACID PRODUCTION PROMOTER AND MELANIN PRODUCTION INHIBITOR - Provided is a hyaluronic acid production promoter and a melanin synthesis inhibitor. The hyaluronic acid production promoter and the melanin synthesis inhibitor of the present invention each contain soybean saponin as an active ingredient. The soybean saponin is preferably soybean saponin aglycone. The soybean saponin aglycone preferably includes soyasapogenol A and/or soyasapogenol B. The hyaluronic acid production promoter and the melanin synthesis inhibitor of the present invention are each administered transdermally or orally. | 04-12-2012 |
20130190538 | PROCESS FOR THE PREPARATION OF PROTOESCIGENIN - A process for the preparation of protoescigenin by hydrolysis of escin isolated from | 07-25-2013 |
20150011802 | PARTIALLY HALOGENATED, HYDROXYLATED FULLERENE AND ALLERGEN ADSORBENT USING THE SAME - Provided are a novel fullerene derivative which can adsorb quickly and efficiently an allergen which may cause a pollen allergy without releasing the allergen again, does not contain a metal or the like which may cause a harmful effect to a human body, and is easily applicable, impregnable, or chemically bondable onto surface of various materials: and a process for producing the same. The fullerene derivative is characterized in that a halogen group and many hydroxyl groups are bonded directly to a fullerene nucleus. In the case that the halogen group is chlorine, the fullerene derivative can be synthesized by a partial hydroxylation of a chlorinated fullerene or a partial chlorination of a hydroxylated fullerene. | 01-08-2015 |
568818000 | Adamantane ring system | 1 |
20130245329 | PROCESS FOR PREPARING ADAMANTANE POLYOL - The present invention provides a process for preparing an adamantane polyol by reacting an adamantane with a ruthenium compound and a hypochlorite in a biphasic water/organic solvent system. The process includes the steps of adding an inorganic adsorbent to a reaction system; and adding an alkali to a reaction mixture to separate the ruthenium compound together with the inorganic adsorbent, and reusing the separated ruthenium compound and inorganic adsorbent in a subsequent reaction. | 09-19-2013 |
568819000 | Bicyclo ring system | 8 |
20090149678 | PROCESS FOR PREPARATION OF PARICALCITOL AND INTERMEDIATES THEREOF - The invention relates to a novel process for the preparation of Paricalcitol and intermediates thereof. | 06-11-2009 |
20090326282 | PROCESS FOR THE MANUFACTURE OF BICYCLIC MOLECULES BY COPPER-CATALYSED PHOTOCHEMICAL CYCLISATION - The present invention relates to a new copper-catalysed photochemnical cyclisation process for the preparation of bicylic molecules useful as intermediates in the manufacture of drugs. In a preferred aspect, the process of the invention may be used to prepare 3-hydroxy-bicyclo[3.2.0]heptane. | 12-31-2009 |
20100010275 | FRAGRANCE COMPOSITION - A fragrance composition containing 0.0005 to 10% by mass of a decalin alcohol as component (a) represented by formula (1a) and 90 to 99.9995% by mass of one or more polycyclic woody-amber fragrances as component (b) selected from the group consisting of 7-acetyl-1,2,3,4,5,6,7,8-octahydro-1,1,6,7-tetramethylnaphthalene, 1,2,3,4,4a,5,6,7-octahydro-2,5,5-trimethyl-2-naphthalenol, 1,2,3,4,4a,7,8,8a-octahydro-2,4a,5,8a-tetramethyl-1-naphthyl formate, 3a-ethyldodecahydro-6,6,9a-trimethylnaphtho[2,1-b]furan, and racemic or optically active dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan; and a cosmetic product, a household product and an environmental/sanitary product containing the fragrance composition. The fragrance composition of the present invention is a highly versatile fragrance composition that brings about an odor of natural ambergris and can attain effects to enhance warmth and an odor quality even in a small amount. | 01-14-2010 |
20100063330 | PARICALCITOL PURIFICATION - Paricalcitol, a synthetic vitamin D analog, is purified to a purity greater than 99.7% by crystallization from solution in isopropyl acetate solvent, followed by filtration and vacuum drying. Isopropyl acetate appears to be unique among commonly available and pharmaceutically acceptable solvents in its ability to precipitate paricalcitol in this high purity, essentially free of isomers thereof. | 03-11-2010 |
20100099923 | Process for the Preparation of Bicyclo[3.1.0]Hexanols - A process for the preparation of a the formula (I): which process comprises the intramolecular cyclopropanation of an epoxide of me formula (II); in the presence of 0.05 to 0.75 equivalents of a secondary amine base and at least one equivalent of an alkyl lithium base, wherein R R | 04-22-2010 |
20100222614 | PROCESS FOR THE PREPARATION OF CALCIPOTRIOL - A process for the preparation of calcipotriol at least including: (a) reacting a C-22 phenylsulfonyl derivative of cholecalciferol of Formula 2, wherein R | 09-02-2010 |
568820000 | The two cyclos share at least three ring carbons (i.e., bridged ring) | 2 |
20100145107 | NOVEL PROPANOL AND RELATED COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS - The present invention a method of improving, enhancing or modifying a fragrance formulation through the addition of an olfactory acceptable amount of a compound of formula: | 06-10-2010 |
20120059196 | METHOD FOR PREPARING A TERPENYLCYCLOHEXANOL - A method for preparing a terpenylcyclohexanol using a terpenylphenol is described. A method for preparing a terpenylcyclohexanol by hydrogenation of a terpenylphenol is also described wherein the method includes hydrogenating the latter in a liquid phase, in the presence of a Raney nickel catalyst including residual aluminium and doped with a mixture of iron and chromium. | 03-08-2012 |