Class / Patent application number | Description | Number of patent applications / Date published |
558286000 | Borate esters (i.e., compounds having boron and carbon each single bonded to the same oxygen, which carbon may be single bonded to any atom but may be multiple bonded only to carbon) | 30 |
558287000 | Boron and oxygen in the same ring | 27 |
558288000 | Carbon in the ring | 27 |
20100267981 | BORON-CONTAINING SMALL MOLECULES - This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate. | 10-21-2010 |
20110207957 | PROCESSES FOR THE PREPARATION OF BIPHENYL COMPOUNDS - The invention concerns processes for the synthesis of a compound of the formula: wherein: R | 08-25-2011 |
20110282090 | PROCESS FOR PREPARING BORONIC ACIDS AND ESTERS IN THE PRESENCE OF MAGNESIUM METAL - The present invention relates to the process for preparing a boronic acid or ester chemically, in which an aromatic compound is reacted with a boronating agent, in the presence of magnesium metal (Mg | 11-17-2011 |
20120184768 | PREPARATION METHOD OF AROMATIC BORONATE COMPOUNDS - Preparation method of aromatic boronate compound is provided, in which the is as follows: reacting aromatic amine Ar-NH | 07-19-2012 |
20120220794 | PROCESS FOR HYDROGENATION OF HALOGENOALKENES WITHOUT DEHALOGENATION - The present invention relates in general to the field of organic chemistry and in particular to the preparation of halogenoalkanes. | 08-30-2012 |
20120289733 | NOVEL BORATE DERIVATIVES AND THEIR APPLICATIONS - Borates, compositions comprising chiral (cyclic and acyclic) and achiral (cyclic and acyclic) borates; chiral (cyclic and acyclic) and achiral (cyclic and acyclic) biborates; and methods for their synthesis. Additionally, a significantly improved synthetic protocol for the synthesis of wide range of boronates starting from borates or biborates and Grignard or organolithium reagents that can be used for kilo lab and commercial scale production. | 11-15-2012 |
20130023689 | PROCESS FOR THE BORYLATION OF ORGANOHALIDES - The present invention relates to a process for the borylation of organohalides. | 01-24-2013 |
20130035501 | PROCESS FOR PREPARING BENZOXABOROLES - The present invention is a process comprising contacting a compound of formula 6: | 02-07-2013 |
20130184484 | PROCESS FOR PREPARING BORONIC ACIDS AND ESTERS IN THE PRESENCE OF MAGNESIUM METAL - The present invention relates to the process for preparing a boronic acid or ester chemically, in which an aromatic compound is reacted with a boronating agent, in the presence of magnesium metal (Mg | 07-18-2013 |
20130324757 | PREPARATION METHOD FOR FLUORINE-CONTAINING OLEFINS HAVING ORGANIC-GROUP SUBSTITUENTS - An object of the present invention is to provide a method that enables the easy and efficient (high yield, high selectivity, low cost) preparation of a fluorine-containing olefin substituted with an organic group or groups from a fluorine-containing olefin. | 12-05-2013 |
20130331595 | Proteasome Inhibitors - The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases. | 12-12-2013 |
20140046086 | PROCESS FOR THE PREPARATION OF TAFLUPROST AND INTERMEDIATES THEREOF - The present invention provides efficient, economical and environmental friendly methods for synthesis of prostaglandin analogs including tafluprost and intermediates thereof. The invention involves a selective oxidation using in situ boronate ester protection and a unique crystallization method to remove the undesired isomers of fluorinated intermediates. | 02-13-2014 |
20140213810 | PREPARATION OF SITAGLIPTIN INTERMEDIATES - The invention relates to the preparation of chiral compounds, in particular to the preparation of chiral compounds which may be used as intermediates for the preparation of anti-diabetic agents, preferably sitagliptin. | 07-31-2014 |
20140336402 | LIGAND FORMING ASYMMETRICAL TRANSFORMATION CATALYST FOR MAKING NEW PHARMACEUTICALS - The present invention provides a catalyst complex or ligand, and compositions thereof, for use in a variety of organic reactions having high reactivity and enantioselectivity. The catalyst is a N-heterocyclic carbene having three fused rings with first and second rings being six-membered rings and the third being a five-membered ring. The first ring is fused to the second and has four substituents. The second ring has two nitrogens flanking a carbene atom with one nitrogen bound to a substituent. The carbene atom may optionally be bonded to a metal. The third ring is fused to the second ring and contains two nitrogens. The third ring of the catalyst has a double bond and two substituents on adjacent non-fused carbons. A non-fused nitrogen of the third ring is partially bonded to another substituent. Methods for the synthesis and use of the catalyst embodiments of the present invention are also provided. | 11-13-2014 |
20140343314 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF - The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases. | 11-20-2014 |
20140357886 | PROCESS FOR THE PREPARATION OF 2-CYANOPHENYLBORONIC ACID AND ESTERS THEREOF - The present invention relates to a process for the synthesis of 2-cyanophenylboronic acid and the esters and salts thereof of formula (II), which are intermediates of the synthesis of active pharmaceutical ingredients such as Perampanel or E2040. formula (II): (II). | 12-04-2014 |
20150065743 | METHODS FOR PRODUCING BORYLATED ARENES - Methods for the selective borylation of arenes, including arenes substituted with an electron-withdrawing group (e.g., 1-chloro-3-fluoro-2-substituted benzenes) are provided. The methods can be used, in some embodiments, to efficiently and regioselectively prepare borylated arenes without the need for expensive cryogenic reaction conditions. | 03-05-2015 |
20150361109 | METHODS FOR PRODUCING BORYLATED ARENES - Methods for the borylation of aromatic compounds using cobalt catalysts are provided. | 12-17-2015 |
20160031913 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF - The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases. | 02-04-2016 |
20160168168 | PROCESS FOR PREPARING BENZOXABOROLES | 06-16-2016 |
558289000 | Nitrogen in the ring | 3 |
20120059184 | System for Controlling the Reactivity of Boronic Acids - A protected organoboronic acid includes a boron having an sp | 03-08-2012 |
20140275601 | PROTECTING GROUPS FOR BORONIC ACIDS - Di- and trivalent protecting groups for organoboronic acids including phenyl boronic acids, benzoxaboroles and benzoxaborins, which are prepared from precursor compounds of formula I: | 09-18-2014 |
20140296557 | Cyclopropyl MIDA Boronate - This disclosure concerns a protected cyclopropylboronic acid comprising a substituted cyclopropyl group and a boronic ester group having a protecting group. The protecting group is an N-methyliminodiacetic acid (MIDA) group or MIDA-based group. | 10-02-2014 |
558290000 | Plural rings each having boron, carbon and oxygen as ring members | 4 |
20110040118 | FLUORINE-CONTAINING BORONIC ACID ESTER COMPOUND AND METHOD FOR PRODUCING THE SAME - A fluorine-containing boronic acid ester compound | 02-17-2011 |
20110166375 | FLUORINE-CONTAINING BORONIC ACID ESTER COMPOUND AND METHOD FOR PRODUCING THE SAME - A fluorine-containing boronic acid ester represented by the general formula: | 07-07-2011 |
20150025262 | BIS(ARYL)ACETAL COMPOUNDS - A bis(aryl)acetal has the formula | 01-22-2015 |
20160090390 | SYNTHETIC METHODS FOR DIBORON REAGENTS AND RELATED COMPOUNDS - The disclosure is directed to diboron compounds, related methods of making, and related intermediate boron and diboron compounds used to make the same. The diboron compounds can be used as reagents to prepare chemical intermediates that are used in pharmaceutical, agrochemical, and specialty electronics industries. The disclosed processes and compounds provide simplified synthetic paths that significantly reduce steps, improve scalability, and minimize costs for producing the diboron reagents. | 03-31-2016 |
558293000 | Three oxygens attached directly to the same boron by nonionic bonding | 1 |
558296000 | Trialkyl borates (i.e., compounds having the structure (RO)B(OR)(OR), wherein the R's represent the same or diverse alkyl groups | 1 |
558297000 | Processes utilizing boric oxide or an inorganic boric acid | 1 |
20090099385 | PROCESS FOR MAKING ALKALINE EARTH METAL BORATED SULFONATES - An alkaline earth metal borated sulfonate prepared by a process comprising reacting a mixture of the following materials(A) (1) at least one of an oil soluble sulfonic acid or alkaline earth sulfonate salt or mixtures thereof (2) at least one source of an alkaline earth metal; and (3) at least one source of boron, in the presence of a mixture of comprising (4) at least one hydrocarbon solvent; and (5) at least one low molecular weight alcohol; and (6) from 0 to less than 10 mole percent, relative to the source of boron, of an overbasing acid, other than the source of boron; and (B) heating the reaction product of (A) to a temperature above the distillation temperatures of (4) and (5) to distill (4), (5) and water of reaction, wherein no additional water is added in the process. | 04-16-2009 |
558298000 | Carbon bonded directly to the boron | 2 |
20140371480 | COPPER CATALYZED HALOGENATON AND REACTION PRODUCTS - A Cu(I)-catalyzed 1,3-halogen migration reaction effectively recycles an activating group by transferring a halogen from an sp | 12-18-2014 |
20150329564 | CHIRAL 4-BORONOPHENYLALANINE (BPA) DERIVATIVE AND METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING 18F-LABELED BPA USING SAID DERIVATIVE - Provided are: a novel chiral 4-boronophenylalanine (BPA) derivative; a method for producing the derivative; and a method for producing | 11-19-2015 |