Class / Patent application number | Description | Number of patent applications / Date published |
548570000 | Chalcogen attached indirectly to the five-membered hetero ring by acyclic nonionic bonding | 20 |
20080234498 | Pyrovalerone Analogues and Therapeutic Uses Thereof - New compounds that bind to monoamine transporters are described. The compounds of the present invention can be racemic or pure R— or S-enantiomers. Certain preferred compounds of the present invention have a high selectively dopamine transporter versus the serotonin transporter. Preferred monoamine transporters for the practice of the present invention include the dopamine transporter, the serotonin transporter and the norepinephrine transporter. | 09-25-2008 |
20100113803 | ENANTIOSELECTIVE SYNTHESIS OF PYRROLIDINES SUBSTITUTED WITH FLAVONES, AND INTERMEDIATES THEREOF - The present invention relates to an enantioselective synthesis of (+)-trans enantiomer of pyrrolidines substituted with flavones, represented by Formula 1 or salts thereof, which are inhibitors of cyclin dependant kinases and can be used for treatment of proliferative disorders such as cancer. | 05-06-2010 |
20140121385 | CRYSTALLINE FORMS OF A 3-[2-METHANESULFONYL-1-(4-TRIFLUOROMETHYL-PHENOXY)ETHYL]PYRROLIDINE COMPOUND - The invention provides crystalline hydrochloride salts of (S)-3-[(S)-2-methanesulfonyl-1-(4-trifluoromethylphenoxy)ethyl]pyrrolidine. This invention also provides pharmaceutical compositions comprising the crystalline salts, processes and intermediates for preparing the crystalline salts, and methods of using the crystalline salts to treat diseases. | 05-01-2014 |
20140243536 | SEROTONIN REUPTAKE INHIBITORS - In one aspect, the invention relates to compounds of formula I: | 08-28-2014 |
548571000 | The chalcogen, X, is in a -C(=X)- group (e.g., 1-phenyl -2-pyrrolidino hexanone-1, etc.) | 2 |
20090048454 | Process for Producing Aminoacetyl Pyrrolidine Carbonitrile Derivative and Intermediate for Production Thereof - Novel intermediates for the production of aminoacetyl pyrrolidine carbonitrile derivatives ensure the safe and efficient production of the compounds. Specifically, the present invention provides a sulfonyloxyacetyl pyrrolidine derivative, represented by the following formula: | 02-19-2009 |
548572000 | The -C(=X)- is part of a -C(=X)X- group wherein the X's are the same or diverse chalcogens (e.g., 3-pyrrolidinemethanol propionates, etc.) | 1 |
20110269975 | NOVEL COMPOUNDS - The present invention related to compounds that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to novel salts thereof, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS). | 11-03-2011 |
548574000 | The chalcogen is in a substituent attached to the ring nitrogen of the five membered hetero ring | 14 |
20120142942 | PROCESSES FOR THE PREPARATION OF ENAMINES - The invention disclosed in this document is related to the field of processes for the preparation of enamines | 06-07-2012 |
20120142943 | PROCESSES FOR THE PREPARATION OF ENAMINES - The invention disclosed in this document is related to the field of processes for the preparation of enamines | 06-07-2012 |
20120142944 | PROCESSES FOR THE PREPARATION OF ENAMINES - The invention disclosed in this document is related to the field of processes for the preparation of enamines | 06-07-2012 |
20140155628 | PROCESSES FOR THE PREPARATION OF ENAMINES - The invention disclosed in this document is related to the field of processes for the preparation of enamines | 06-05-2014 |
20140155629 | PROCESSES FOR THE PREPARATION OF ENAMINES - The invention disclosed in this document is related to the field of processes for the preparation of enamines | 06-05-2014 |
20140155630 | Processes for the Preparation of Enamines - The invention disclosed in this document is related to the field of processes for the preparation of enamines | 06-05-2014 |
20140235872 | NOVEL LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY - The instant invention provides for novel cationic lipids that can be used in combination with other lipid components such as cholesterol and PEG-lipids to form lipid nanoparticles with oligonucleotides. It is an object of the instant invention to provide a cationic lipid scaffold that demonstrates enhanced efficacy along with lower liver toxicity as a result of lower lipid levels in the liver. The present invention employs low molecular weight cationic lipids with one short lipid chain to enhance the efficiency and tolerability of in vivo delivery of siRNA. | 08-21-2014 |
20150315112 | NOVEL LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY - The instant invention provides for novel cationic lipids that can be used in combination with other lipid components such as cholesterol and PEG-lipids to form lipid nanoparticles with oligonucleotides. It is an object of the instant invention to provide a cationic lipid scaffold that demonstrates enhanced efficacy along with lower liver toxicity as a result of lower lipid levels in the liver. The present invention employs low molecular weight cationic lipids with one short lipid chain to enhance the efficiency and tolerability of in vivo delivery of siRNA. | 11-05-2015 |
20150329475 | QUATERNARY AMMONIUM HYDROXIDES - A composition including (a) a quaternary ammonium hydroxide having a general formula (I): | 11-19-2015 |
20150329507 | PROCESSES FOR THE PREPARATION OF ENAMINES - The invention disclosed in this document is related to the field of processes for the preparation of enamines | 11-19-2015 |
20150329508 | Processes for the Preparation of Enamines - The invention disclosed in this document is related to the field of processes for the preparation of enamines | 11-19-2015 |
20150329509 | PROCESSES FOR THE PREPARATION OF ENAMINES - The invention disclosed in this document is related to the field of processes for the preparation of enamines | 11-19-2015 |
548575000 | Carbocyclic ring bonded directly to the chalcogen | 2 |
20090012314 | Process for Production of Lasofoxifene or Analogue Thereof - Disclosed is a novel process for production of lasofoxifene, nafoxidine or an analogue thereof, which comprises reduced number of reaction steps, has a high efficiency, and is practically advantageous. For the production of lasofoxifene or an analogue thereof, a compound represented by the formula (4) is used as an intermediate. The compound represented by the formula (4) can be produced using compounds represented by the formulae (1) to (3) as starting compounds by performing the coupling of the three components in one step. | 01-08-2009 |
548576000 | The substituent on the ring nitrogen of the five-membered hetero ring contains a bicyclo carbocyclic ring system | 1 |
20100160648 | STEREOSELECTIVE HYDROGENATION PROCESS FOR PREPARING CIS-6-PHENYL-5-[4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYL]-2-METHOXY-5,6,7,8-TE- TRAHYDRONAPHTHALENE HYDROCHLORIDE - This invention provides an improved process for preparing cis-6-phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-2-methoxy-5,6,7,8-tetrahydronaphthalene hydrochloride which is an intermediate for the preparation of (−)-cis-6-phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6,7,8-tetrahydronaphthalene-2-ol which is useful for the treatment of osteoporosis. | 06-24-2010 |