Class / Patent application number | Description | Number of patent applications / Date published |
546329000 | Nitrogen attached indirectly to the six-membered hetero ring by nonionic bonding | 61 |
20090012302 | METHOD OF ISOLATING A NUCLEIC ACID USING A MATERIAL CONTAINING AN AMINO GROUP AND A CARBOXYL GROUP AND POSITIVELY CHARGED AT A FIRST PH AND A SOLID MATERIAL FOR NUCLEIC ACID ISOLATION USED FOR THE METHOD - Provided are a method of isolating a nucleic acid from a sample and a solid material for isolating the nucleic acid which can be used for the above method. The method includes contacting the sample with a bifunctional material containing an amino group and a carboxyl group at a first pH to bind the nucleic acid to the bifunctional material, the bifunctional material being positively charged at the first pH; and releasing the nucleic acid at a second pH which is higher than the first pH. | 01-08-2009 |
20090082573 | Methods For Preparation Of Pyridylamines - Alternate methods for preparing functionalized pyridyl-amine products from pyridinyl starting materials are provided herein. In addition, these alternately-prepared functionalized pyridyl-amines can be used as ligands or ligand precursors in catalytic compositions, e.g. for use in alkene oligomerization reactions. | 03-26-2009 |
20090281325 | METHOD FOR SELECTIVELY PRODUCING PRIMARY AMINE COMPOUND - Disclosed is a method for producing a primary amine compound represented by the formula (3): | 11-12-2009 |
20100029952 | Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems - Fluorophores derived from photoactivatable azide-pi-acceptor fluorogens or from a thermal reaction of an azide-pi-acceptor fluorogen with an alkene or alkyne are disclosed. Fluorophores derived from a thermal reaction of an alkyne-pi-acceptor fluorogen with an azide are also disclosed. The fluorophores can readily be activated by light and can be used to label a biomolecule and imaged on a single-molecule level in living cells. | 02-04-2010 |
20100174090 | METHODS OF PREPARING PRIMARY, SECONDARY AND TERTIARY CARBINAMINE COMPOUNDS IN THE PRESENCE OF AMMONIA - The present application relates to novel methods for the preparation of primary, secondary and tertiary carbinamine compounds, particularly the preparation of compounds of formulae I, IV and VI, from a carbonyl compound of formula II in the presence of ammonia or an ammonium equivalent of the formula NH | 07-08-2010 |
20100197930 | PROCESS FOR PRODUCING TOLUIDINE COMPOUND - Because fluazinam is excellent as an active ingredient of pesticides and highly useful, it is desired to produce it efficiently in a proper form with simple operations at low cost in an environmentally friendly manner. The desired product is obtained in good yields with simple operations by using industrially advantageous reaction systems by a process comprising (1) a step of reacting ACTF and DCDNBTF in the presence of an alkali component, a solvent selected from the group consisting of ketones, nitriles, ethers and esters and a sufficient amount of water to substantially dissolve the alkali component, (2) a step of neutralizing or acidifying the reaction mixture with an acid and (3) a step of removing the solvent by distillation from the mixture containing fluazinam as the reaction product and the reaction solvent to precipitate crystals the product. | 08-05-2010 |
20100274021 | METHOD FOR PRODUCING 2,2-DIFLUOROETHYLAMINE DERIVATIVES BY IMINE HYDROGENATION - Process for preparing 2,2-difluoroethylamine derivatives, wherein compounds of the general formula (IV) are hydrogenated to the corresponding 2,2-difluoroethylamine derivatives of the general formula (III), where the A radical is as defined in the description: | 10-28-2010 |
20100298572 | METHODS OF PREPARING SECONDARY CARBINAMINE COMPOUNDS WITH BORONIC ACIDS - The present application relates to novel methods for the preparation of secondary carbinamine compounds, particularly the preparation of secondary carbinamine compounds of the formula Ia, formula Ib or formula IV from aldehydes of the formula II and boronic acids of the formula III or formula V, in the presence of ammonia or an ammonia equivalent of the formula NH | 11-25-2010 |
20110306770 | Process for preparing 2-2-difluoroethylamine derivatives by alkylation with 2-2-difluoroethyl-1-haloethanes - Process for preparing 2,2-difluorethylamine derivatives of the general formula (III) | 12-15-2011 |
20120022264 | METHOD FOR PRODUCING 2,2 DIFLUOROETHYLAMINE DERIVATIVES BY IMINE HYDROGENATION - Process for preparing 2,2-difluoroethylamine derivatives, wherein compounds of the general formula (IV) are hydrogenated to the corresponding 2,2-difluoroethylamine derivatives of the general formula (III), where the A, R | 01-26-2012 |
20120123130 | PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE DERIVATIVES STARTING FROM N-(2,2-DIFLUOROETHYL)PROP-2-EN-1-AMINE - Process for the preparation of 2,2-difluoroethylamine derivatives of the formula (IV) | 05-17-2012 |
20120157686 | a-OLEFIN MANUFACTURING PROCESS - In an α-olefin manufacturing process by the oligomerization of ethylene using an iron complex of a diimine of a 2,6-diacylpyridine or a 2,6-pyridinecarboxaldehyde, in which certain substituted iminoaryl groups are present, less higher molecular weight unwanted products are produced when the diimine and/or its precursor arylamine does not have impurities with substitution on a second ortho position to the imino group. This leads to less fouling of the process apparatus and higher yields of desired α-olefins. | 06-21-2012 |
20130123506 | SUBSTITUTED ENAMINOCARBONYL COMPOUNDS - The present invention relates to novel substituted enaminocarbonyl compounds, to processes for their preparation and to their use for controlling animal pests, especially arthropods, in particular insects. | 05-16-2013 |
20130245276 | PROCESS FOR HOMOGENEOUSLY CATALYZED, HIGHLY SELECTIVE DIRECT AMINATION OF PRIMARY ALCOHOLS WITH AMMONIA TO PRIMARY AMINES WITH A HIGH VOLUME RATIO OF LIQUID PHASE TO GAS PHASE AND/OR HIGH PRESSURES - The present invention relates to a process for preparing primary amines comprising the process steps
| 09-19-2013 |
20130331580 | PROCESS FOR THE DIRECT AMINATION OF ALCOHOLS USING AMMONIA TO FORM PRIMARY AMINES BY MEANS OF A XANTPHOS CATALYST SYSTEM - The present invention relates to a chemocatalytic liquid-phase process for the direct one-stage amination of alcohols to primary amines by means of ammonia in high yields using a catalyst system containing at least one transition metal compound and a xantphos ligand. | 12-12-2013 |
20150322011 | PROCESS FOR PREPARING 2,2-DIFLUOROETHYLAMINE DERIVATIVES BY ALKYLATING 2,2-DIFLUOROETHYLAMINE - A method for preparing a 2,2-difluoroethylamine of the formula (III) in which 2,2-difluoroethylamine of the formula (I) is reacted with a halide of the formula (II) in the presence of a tertiary nitrogen base: | 11-12-2015 |
20150344428 | Catalytic Manufacturing Method for Imine Having No Substituent Group on the Nitrogen, and Use for the Imine Produced - The present invention relates to a method for manufacturing an imine having no substituent group on the nitrogen by using, as a catalyst, a metal complex on an organic azide compound, and more specifically relates to a method in which a metal-complex catalyst is used to produce, from an organic azide having an alpha-hydrogen, an imine having no substituent group on the nitrogen via a continuous nitrogen removal and 1,2-hydrogen transfer reaction. The imine having no substituent group on the nitrogen manufactured by means of the method of the present invention can synthesise diverse coupling products comprising amine compounds by means of reactions with diverse nucleophiles. | 12-03-2015 |
20150380656 | MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME - A compound for an organic electroluminescence device and an organic electroluminescence device, the compound being represented by the following Chemical Formula 1: | 12-31-2015 |
20160145193 | DUAL SITE CATALYST FOR MILD, SELECTIVE NITRILE REDUCTION - A ruthenium bis(pyrazolyl)borate scaffold that enables cooperative reduction reactivity in which boron and ruthenium centers work in concert to effect selective nitrile reduction is provided. The pre-catalyst compound [κ | 05-26-2016 |
546330000 | Cyano attached indirectly to the six-membered hetero ring by nonionic bonding | 10 |
20080207910 | Process for the preparation of certain substituted sulfilimines - Cyano-substituted sulfilimines are produced efficiently and in high yield from the corresponding sulfides by reaction with cyanamide and hypochlorite. | 08-28-2008 |
20100240900 | DISPERSIBLE CARBON NANOSPHERES AND METHODS FOR MAKING SAME - The carbon nanomaterials and methods relate to methods for causing carbon nanospheres to be readily dispersible in a material. The carbon nanospheres are rendered dispersible using a cationic surfactant. The surfactant includes one or more cationic group that can bond to the surface of the carbon nanospheres, without detrimentally affecting the unique properties of carbon nanospheres. The dispersible carbon nanospheres can be dried (i.e., solvent is driven off) while maintaining their dispersibility in solvents and other materials. | 09-23-2010 |
20110319629 | TITANIUM COMPOUNDS AND PROCESS FOR CYANATION OF IMINES - The present invention relates to titanium catalysts for synthesis reactions produced by bringing a reaction mixture comprising a titanium alkoxide and a ligand in contact with water, wherein the ligand is represented by the general formula (e): wherein R | 12-29-2011 |
20120004417 | FLUORINATION OF AROMATIC RING SYSTEMS - This disclosure relates to reagents and methods useful in the synthesis of aryl fluorides, for example, in the preparation of | 01-05-2012 |
20120165538 | PROCESS FOR THE PREPARATION OF CERTAIN SUBSTITUTED SULFILIMINES - Cyano-substituted sulfilimines and sulfoximines are produced efficiently and in high yield from the corresponding sulfides by reaction with cyanamide and hypochlorite. | 06-28-2012 |
20120209007 | TITANIUM COMPOUNDS AND PROCESS FOR CYANATION OF IMINES - The present invention relates to titanium catalysts for synthesis reactions produced by bringing a reaction mixture comprising a titanium alkoxide and a ligand in contact with water, wherein the ligand is represented by the general formula (e): wherein R | 08-16-2012 |
20130217883 | METHODS OF PRODUCING SULFILIMINE COMPOUNDS - Methods of producing a sulfilimine compound, such as N-cyano-S-methyl-S-[1-(6-trifluoromethyl-3-pyridinyl)ethyl]sulfilimine or other substituted sulfilimine compound. The method includes combining a sulfide compound, cyanamide, a hypochlorite compound, and a base, and oxidizing the sulfide compound to form the sulfilimine compound. The sulfide compound may include a 2-trifluoromethyl-5-(1-substituted)alkyl-thiopyridine compound. The base may include sodium hydroxide. A buffer, such as a phosphate buffer, may, optionally, be used in the reaction. | 08-22-2013 |
20140163236 | PROCESS FOR THE PREPARATION OF CERTAIN SUBSTITUTED SULFILIMINES - Cyano-substituted sulfilimines are produced efficiently and in high yield from the corresponding sulfides, cyanamide and hypochlorite by adding the sulfide to a solution of the cyanamide and hypochlorite in the presence of a nitrile solvent while maintaining the pH from about 8 to about 12. | 06-12-2014 |
20160046580 | METHODS OF PRODUCING SULFILIMINE COMPOUNDS - Methods of producing a sulfilimine compound, such as N-cyano-S-methyl-S-[1-(6-trifluoromethyl-3-pyridinyl)ethyl]sulfilimine or other substituted sulfilimine compound. The method includes combining a sulfide compound, cyanamide, a hypochlorite compound, and a base, and oxidizing the sulfide compound to form the sulfilimine compound. The sulfide compound may include a 2-trifluoromethyl-5-(1-substituted)alkyl-thiopyridine compound. The base may include sodium hydroxide. A buffer, such as a phosphate buffer, may, optionally, be used in the reaction. | 02-18-2016 |
20160137603 | PROCESS FOR THE PREPARATION OF CERTAIN SUBSTITUTED SULFILIMINES - Cyano-substituted sulfilimines are produced efficiently and in high yield from the corresponding sulfides, cyanamide and hypochlorite by adding the sulfide to a solution of the cyanamide and hypochlorite in the presence of a nitrile solvent while maintaining the pH from about 8 to about 12. | 05-19-2016 |
546332000 | Plural acyclic nitrogens bonded directly to the same carbon or single bonded directly to each other | 9 |
20090176990 | PROCESS FOR PRODUCING NITROGUANIDINE DERIVATIVES - Disclosed is an improved process for producing nitroguanidine derivatives represented by the following general formula (3), which has an insecticidal activity, or a salt thereof. Specifically, disclosed is a process for producing nitroguanidine derivatives represented by the following general formula (3) or a salt thereof, in which nitroisourea derivatives represented by the following general formula (1) or a salt thereof and compounds represented by the following general formula (2) or a salt thereof are reacted in the presence of a base in an aqueous solution wherein an inorganic salt is dissolved at not less than 50% of its saturated solubility, | 07-09-2009 |
20110184184 | METHOD FOR SEPARATING AND PURIFYING alpha- UNSATURATED AMINE COMPOUND - A method for purifying an α-unsaturated amine compound represented by Formula (1), the method comprising a step of extracting with water the compound of Formula (1) from a crude product of the α-unsaturated amine compound represented by Formula (1), and a step of extracting with a pyridine solvent the α-unsaturated amine compound of Formula (1) from the aqueous solution containing the compound of Formula (1) obtained in the previous step to obtain a pyridine solvent solution of the compound of Formula (1): | 07-28-2011 |
20120157687 | IMPROVED PROCESS FOR THE PREPARATION OF ARYLPYRIDINYL COMPOUNDS - A process is described for the preparation of arylpyridine compounds by aryl-aryl cross-coupling reactions between a halopyridine and an arylmagnesium halide carried out in the presence of a catalytic amount of a zinc salt and a catalytic amount of palladium complex with a bidentate phosphine. The zinc salt is preferably selected from ZnCl | 06-21-2012 |
20130035493 | Process for Preparing Form A of Atazanavir Sulfate - A process of making Form A of atazanavir sulfate comprises: a) mixing atazanavir free base with a solvent selected from the group consisting of methanol (MeOH), ethanol (EtOH), isopropanol (IPA), N-methylprrolidone (NMP) and combinations thereof; b) reacting sulfuric acid with the atazanavir free base in the mixture formed in step a) to form a reaction solution comprising atazanavir sulfate; c) mixing an antisolvent with the reaction solution; d) seeding the mixture formed in step c) with an effective amount of Form A of atazanavir sulfate to form a seeded mixture comprising Form A of atazanavir sulfate; and e) isolating Form A of atazanavir sulfate in solid form from the seeded mixture; wherein the antisolvent is selected from the group consisting of methyl tert-butyl ether (MTBE), ethyl acetate (EtOAc), acetonitrile (MeCN), isopropyl acetate (IPAc), cyclohexane, and combinations thereof. In one alternative, step c) may be performed before step b). In another alternative, step d) may be carried out concurrent with or prior to step c). | 02-07-2013 |
20130041156 | AZAPEPTIDE DERIVATIVES - This invention relates to novel compounds that are azapeptides, and pharmaceutically acceptable salts thereof. More specifically, the invention relates to novel azapeptide compounds that are derivatives of the HIV protease inhibitor atazanavir sulfate. This invention also provides pyrogen-free compositions comprising one or more compounds of the invention and a carrier, and the use of the disclosed compounds and compositions in methods of treating diseases and conditions that are treated by administering HIV protease inhibitors. The invention also relates to the use of one or more of the disclosed compounds as reagents in analytical studies involving atazanavir. | 02-14-2013 |
20130217884 | ETHYNYLPHENYLAMIDINE COMPOUND OR SALT THEREOF, METHOD FOR PRODUCING SAME, AND FUNGICIDE FOR AGRICULTURAL AND HORTICULTURAL USE - An object of the present invention is to provide a novel fungicide having an excellent fungicidal activity. The compound used as the fungicide of the present invention is an ethynylphenylamidine compound or a salt thereof, the compound being represented by Formula (1): | 08-22-2013 |
20140005406 | PROCESSES FOR THE PRODUCTION OF N-SUBSTITUTED SULFOXIMINE PYRIDINE N-OXIDES | 01-02-2014 |
20140031559 | TUNABLE PHENYLACETYLENE HOSTS - A compound, or a salt thereof, having the formula | 01-30-2014 |
20140343290 | PROCESS FOR THE PREPARATION OF ATAZANAVIR OR ITS BISULFATE SALT - The present invention relates to an improved process for the preparation of atazanavir bisulfate, an inhibitor of retroviral aspartate protease. The process of the present invention comprises conversion of 1,1-dimethylethyl[(2S,3R)-4-chloro-3-hydroxy-phenylbutan-2-yl]carbamate (Formula II) into 1-[4-(pyridine-2-yl)-phenyl]-4(S)-5 hydroxy-2-N-tert-butoxycarbonylamino-5(S)—N—(N-methoxycarbonyl-(L)-tert-leucyl)amino-6-phenyl-2-azahexane (Formula VII) without isolating intermediate compounds formed therein, followed by its subsequent conversion to atazanavir or its bisulfate salt. | 11-20-2014 |
546333000 | The six-membered hetero ring and another ring bonded directly to the same carbon | 1 |
20140100371 | PROCESS FOR PREPARING AZOMETHINES FROM ALPHA-OXOCARBOXYLATES, AMINES AND ARYL BROMIDES - A process for preparing azomethines of the general formula (V) where R is an optionally substituted carbocyclic aromatic radical having 6 to 24 carbon atoms or an optionally substituted alkyl radical or an optionally substituted heteroaromatic radical having 5 to 24 carbon atoms, and R | 04-10-2014 |
546334000 | Chalcogen attached indirectly to the six-membered hetero ring by nonionic bonding | 22 |
20080275246 | PROCESS FOR HALOMETHYL ETHERS OF HYDROXYIMINOMETHYL QUATERNARY PYRIDINIUM SALTS - A halide salt of a 1-(hydroxyiminomethyl-1-pyridino)-3-(halomethyl)-2-oxapropane is prepared by adding a pyridinealdoxime to a bis-halomethylether in such a manner that the bis-halomethylether is maintained in excess throughout the addition. This procedure produces the halide salt of a 1-(hydroxyiminomethyl-1-pyridino)-3-(halomethyl)-2-oxapropane in high yield and purity, which facilitates its use as an intermediate in the manufacture of an asymmetrically substituted 1,3-di(1-pyridino)-2-oxapropane, a class of compounds that are generally useful antidotes to various toxic agents. A prominent member of the class is the dimethylsulfonate salt of 1-(2-hydroxyiminomethyl-1-pyridino)-3-(4-carbamoyl-1-pyridino)-2-oxapropane. The use of mercaptoalkyl-functionalized polymers is disclosed as a preferred metal ion scavenger for a final purification step in the manufacture of these compounds. | 11-06-2008 |
20110144348 | VOLTAGE-SENSITIVE DYE AND METHOD OF PREPARING THE SAME - Provided is a voltage sensitive dye represented by Formula 7. | 06-16-2011 |
20130197234 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE COMPOUND - The present invention relates to methods for producing an optically active amine compound via a highly enantioselective hydrogenation reaction of an imine compound, wherein the imine compound is hydrogenated using a ruthenium metal complex having high catalytic activity and represented by Formula (1) | 08-01-2013 |
20140121380 | METHOD FOR INDUSTRIALLY PREPARING NITROGEN SUBSTITUTED AMINO-5,6,7,8-TETRAHYDRONAPHTHOL | 05-01-2014 |
546335000 | The chalcogen, X, is part of a -C(=X)X- group, wherein the X's are the same or diverse chalcogens | 6 |
20100274022 | G PROTEIN-COUPLED RECEPTOR INHIBITOR AND PHARMACEUTICAL PRODUCT - Disclosed are a substance and a pharmaceutical product inhibiting activation of a G protein-coupled receptor. Specifically disclosed is a G protein-coupled receptor inhibitor containing a specific compound represented by the following formula (1): | 10-28-2010 |
20110098477 | Method Of Producing Compound Having Anti-Hcv Activity - There is provided a convenient and inexpensive method of producing a compound which has a high activity of inhibiting replication of hepatitis C virus (HCV) and is useful for preventing and treating a liver disease caused by HCV infection. | 04-28-2011 |
20110178305 | PROCESS FOR THE PREPARATION OF 3,4-EPOXY-2-AMINO-1-SUBSTITUTED BUTANE DERIVATIVES AND INTERMEDIATE COMPOUNDS THEREOF - The present invention relates to a process for the preparation of threo-3,4-epoxy-2-amino-1-substituted butane derivatives represented by general Formula I which comprises reacting compound of Formula III or salt thereof with an active ester of acid of Formula IV and treating the product thereof with base. The carbon atom bonded to the radical R | 07-21-2011 |
20130281705 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS - Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed. | 10-24-2013 |
20150376127 | PROCESS FOR PREPARING DESMOSINE, ISODESMOSINE, AND DERIVATIVES THEREOF - A process for preparing a compound represented by the following general formula (I) or a salt thereof, which comprises reacting lysine or a protective product thereof or a salt thereof with allysine or a protective product thereof in the presence of a specific trifluoromethane sulfonate to obtain a compound having pyridine ring or a salt thereof. | 12-31-2015 |
20190144390 | PROCESS FOR PREPARING DEUTERATED DESMOSINE AND DERIVATIVES THEREOF | 05-16-2019 |
546336000 | Acyclic nitrogen bonded directly to a -C(=X)- group, wherein X is chalcogen | 11 |
20100222593 | METHOD FOR PRODUCING 2,2-DIFLUOROETHYLAMINE DERIVATIVE BY AMIDE HYDROGENATION - Process for preparing 2,2-difluoroethylamine derivatives, wherein compounds of the general formula (IV) are reduced to the corresponding 2,2-difluoroethylamine derivatives of the general formula (III), where the A radical is as defined in the description: | 09-02-2010 |
20100305331 | ALPHA KETOAMIDE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS - The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them. | 12-02-2010 |
546337000 | Additional ring containing | 9 |
20090270631 | Therapeutic agent for diabetes - The present invention provides an agent for the prophylaxis or treatment of diabetes, which is associated with a fewer side effects such as body weight gain, adipocyte accumulation, cardiac hypertrophy and the like, and which contains a compound represented by the formula: wherein each symbol is as defined in the specification, or a salt thereof or a prodrug thereof. | 10-29-2009 |
20100022781 | TRYPSIN-LIKE SERINE PROTEASE INHIBITORS, AND THEIR PREPARATION AND USE - The invention relates to inhibitors of trypsin-like serine proteases of the general formula (I) which, as well as plasmin, also inhibit plasma kallikrien, and to their preparation and use as medicaments, preferably for treatment of blood loss, especially in the case of hyperfibrinolytic states, in organ transplants or heart surgery interventions, in particular with a cardiopulmonary bypass, or as a constituent of a fibrin adhesive. | 01-28-2010 |
20100184990 | Process for the Manufacture of Flecainide - The invention describes an improved process for the manufacture of a Flecainide intermediate viz N-(pyridin-2-ylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide (II). It consists of reacting 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with an acid chloride in a solvent mixture in presence of a base at −10 to −50° C. The resulting mixed anhydride is then condensed with 2-aminomethylpyridine at −10 to −40° C. and the resulting product after aqueous workup is purified by crystallization. This affords the intermediate II in vastly improved yields and quality. The intermediate II on catalytic hydrogenation affords N-(2-piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide (Flecainide), isolated as its acetate. | 07-22-2010 |
20100249424 | METHOD FOR PREPARING 5-HALOALKYL-4,5-DIHYDROISOXAZOLE DERIVATIVES - Disclosed is a method for preparing a compound of Formula 1 | 09-30-2010 |
20100292485 | PROCESS FOR THE PREPARATION OF A 2-PYRIDYLETHYLCARBOXAMIDE DERIVATIVE - Process for the preparation of a N-[2-(2-pyridinyl)ethyl]carboxamide derivative of general formula (I) or a salt thereof | 11-18-2010 |
20100317865 | ENZYME AND RECEPTOR MODULATION - Covalent conjugates of an α,α-disubstituted glycine ester and a modulator of the activity of a target intracellular enzyme or receptor, wherein the ester group of the conjugate is hydrolysable by one or more intracellular carboxylesterase enzymes to the corresponding acid and the α,α-disubstituted glycine ester is conjugated to the modulator at a position remote from the binding interface between the inhibitor and the target enzyme or receptor pass into cells and the active acid hydrolysis product accumulates within the cells. | 12-16-2010 |
20110009638 | METHOD FOR PREPARING 3-TRIFLUOROMETHYL CHALCONES - Disclosed is a method for preparing a compound of Formula 1 wherein Q and Z are as defined in the disclosure comprising distilling water from a mixture comprising a compound of Formula 2, a compound of Formula 3, a base comprising at least one compound selected from the group consisting of alkaline earth metal hydroxides of Formula 4 wherein M is Ca, Sr or Ba, alkali metal carbonates of Formula 4a wherein M | 01-13-2011 |
20120165539 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS - The present invention relates to a compound according to formula: (I); wherein X | 06-28-2012 |
20120226047 | COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM - The present invention relates to the use of certain high potency savory (‘umami’) taste modifiers, as savory flavoring agents and/or enhancers of monosodium glutamate, for the preparation of foods, beverages, and other comestible compositions, and to processes for preparing food flavorant compositions for use in the preparation of comestible food and drink. | 09-06-2012 |
546338000 | Acyclic nitrogen bonded directly to chalcogen | 1 |
20140142318 | PYRIDYLACETYLENES FOR USE AS RADIOTRACERS AND IMAGING AGENTS - The present invention relates to novel pyridylacetylene derivatives, their preparation, their use as radiotracers/markers and compositions containing them. | 05-22-2014 |