Class / Patent application number | Description | Number of patent applications / Date published |
546180000 | Halogen or nitro attached directly or indirectly to the quinoline ring system by nonionic bonding | 7 |
20100022777 | Process for the Preparation of E-3-[2-(7-Chloro-2-Quinolinyl)Ethenyl]Benzaldehyde - An improved, scalable, and environmentally friendly manufacturing procedure for the preparation of E-3-[2-(7-chloro-2-quinolinyl)ethenyl]benzaldehyde, which is a key early intermediate used in the preparation of montelukast sodium, and the compound prepared by such a process. | 01-28-2010 |
20100099879 | PROCESS FOR MAKING MONTELUKAST AND INTERMEDIATES THEREFOR - The reaction of methylmagnesium halide is improved by the presence of a cerium (III) salt such as cerium trichloride. The reactions are typically associated with the production of montelukast, a pharmaceutically useful compound of the following formula | 04-22-2010 |
20100217004 | PROCESS FOR THE PRODUCTION OF TERTIARY ALCOHOLS | 08-26-2010 |
20110144344 | FLUORIDATION OF IODONIUM SALTS - The present invention provides an improved method for fluoridation of an iodonium salt wherein a solution of the iodonium salt comprising a free radical trap is stored before the reaction is carried out. The method of the invention may be automated, which is particularly convenient when the method of the invention is radiofluoridation. As such the present invention also provides a cassette comprising the iodonium salt solution suitable for carrying out the method of the invention on an automated synthesizer. | 06-16-2011 |
20120215002 | SYNTHESIS OF OPTICALLY ACTIVE INTERMEDIATE FOR THE PREPARATION OF MONTELUKAST - The present invention relates to the synthesis of optically active alcohols by means of enantioselective hydrogenation of ketones in biphasic systems. In particular the present invention relates to the synthesis of an optically active alcohol of general formula (1). | 08-23-2012 |
20160176901 | Reagents and Methods for Fluorinating a Substrate | 06-23-2016 |
20160185691 | One-Component Reagent for the Fluoroalkylation Reaction - A composition, consisting essentially of copper, a fluoroalkyl group, and a ligand comprising at least one group-V donor. The molar ratio of copper to the fluoroalkyl group is approximately 1. | 06-30-2016 |