Class / Patent application number | Description | Number of patent applications / Date published |
544182000 | Asymmetrical (e.g., 1, 2, 4-triazines, etc.) | 33 |
20090312544 | METHOD FOR PREPARING LAMORTRIGINE AND ITS INTERMEDIATE 2,3-DICHLOROBENZOYL CHLORIDE - A method for preparing 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine, commonly known as lamotrigine, is disclosed. A method of preparing the intermediate, 2,3-dichlorobenzoyl chloride, by photochlorination of 2,3-dichlorobenzotrichloride followed by hydrolysis is also disclosed. The intermediate may then be used in the preparation of lamotrigine. | 12-17-2009 |
20100087638 | PROCESS FOR THE PREPARATION OF LAMOTRIGINE - A novel process for the preparation of lamotrigine and its intermediates is devised. | 04-08-2010 |
20100317851 | LUMINOPHORES - There is described novel organo-platinum luminophores comprising a complex of formula (I). The luminophores have application as the emissive component in organic light emitting diodes. | 12-16-2010 |
20120108812 | PROCESS FOR SUBSTITUTED 3-AMINO-5-OXO-4,5-DIHYDRO-[1,2,4]TRIAZINES - Processes including preparation of trans-4-[(3-amino-5-oxo-4,5-dihydro-[1,2,4]triazin-6-ylmethyl)-carbamoyl]-cyclohexanecarboxylic acid methyl ester, and its conversion to trans-4-(4-amino-5-substituted-imidazo[5,1-f][1,2,4]triazin-7-yl)-cyclohexanecarboxylic acid compounds. | 05-03-2012 |
20120136149 | METHOD FOR PREPARING 5-CHLORO-N-(METHYL)THIOPHEN-2-CARBOXAMIDE DERIVATIVE AND INTERMEDIATE USED THEREIN - Disclosed are: a method for preparing a 5-chloro-N-({(5S)-2-oxo-3-[4-(5,6-dihydro-4H-[1,2,4]triazin- | 05-31-2012 |
20120142919 | METHOD FOR SYNTHESIZING LAMOTRIGINE - The invention relates, in general, to an improved process for preparing lamotrigine, Formule (I). Processes for preparing and purifying lamotrigine, including lamotrigine hydrate, lamotrigine monohydrate and anhydrous lamotrigine, are described. | 06-07-2012 |
20120157681 | LUMINOPHORES - There is described novel organo-platinum luminophores comprising a complex of formula I: | 06-21-2012 |
20130005967 | METHOD FOR PREPARING (R)-3-(3-FLUORO-4-(1-METHYL-5,6-DIHYDRO-1,2,4-TRIAZIN-4(1H)-YL)PHENYL)-5-- (SUBSTITUTED METHYL)OXAZOLIDIN-2-ONE DERIVATIVES - Provided are a method for preparing (R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(substituted methyl)oxazolidin-2-one derivatives, which are oxazolidinone antibiotic compounds having a cyclic amidrazone group, represented by Chemical Formula 1, and intermediates thereof, and uses 3,4-difluoro-4-nitrobenzen as a starting material. According to the preparation method of the present invention, (R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(substituted methyl)oxazolidin-2-one derivatives, which are useful as oxazolidinone antibiotics, can be prepared in high purity and high yield in a simpler manner than conventional methods. | 01-03-2013 |
20130053559 | 1,2,4-Triazine Suitable as a Vulcanization Accelerator and Method for Producing Same - A 1,2,4-triazine of formula (I): | 02-28-2013 |
20130085276 | CARBOXYLATION CATALYSTS - The use of a complex of the form Z—M—OR in the carboxylation of a substrate is described. The group Z is a two-electron donor ligand, M is a metal and OR is selected from the group consisting of OH, alkoxy and aryloxy. The substrate may be carboxylated at a C—H or N—H bond. The metal M may be copper, silver or gold. The two-electron donor ligand may be a phosphine, a carbene or a phosphite ligand. Also described are methods of manufacture of the complexes and methods for preparing isotopically labelled caboxylic acids and carboxylic acid derivatives. | 04-04-2013 |
20130231479 | ARYLOXYUREA COMPOUND AND PEST CONTROL AGENT - The present invention provides a pest control agent, acaricide or fungicide that contains, as the active ingredient thereof, at least one type of compound selected from the aryloxyurea compounds represented by formula (V) (wherein R | 09-05-2013 |
20150065706 | OLIGOMER-CONTAINING SUBSTITUTED AROMATIC TRIAZINE COMPOUNDS - The invention relates to (among other things) methods for treatment comprising administering oligomer-containing substituted aromatic triazine compounds. A compound of the invention, when administered by any of a number of administration routes, exhibits one or more advantages over corresponding compounds lacking the oligomer. | 03-05-2015 |
20150361099 | PROCESSES FOR MAKING ALKYLATED ARYLPIPERAZINE AND ALKYLATED ARYLPIPERIDINE COMPOUNDS INCLUDING NOVEL INTERMEDIATES - Novel processes, and intermediates, for making alkylated arylpiperazine and alkylated arylpiperidine compounds of the general formulas (I) and (VII), respectively | 12-17-2015 |
20160194294 | OLIGOMER-CONTAINING SUBSTITUTED AROMATIC TRIAZINE COMPOUNDS | 07-07-2016 |
544183000 | Polycyclo ring system having the asymmetrical triazine ring as one of the cyclos | 19 |
20090318691 | Novel Aromatic AZA Heterocycles, Method of Production and Use of the Material in Organic Electronics - An electron transport material based on fused aromatic electron-deficient compounds. The accumulation of aromatic rings with an electron deficiency allows free-radical anions to be stabilized very efficiently in these systems. | 12-24-2009 |
20100056781 | INTERMEDIATES USEFUL IN PREPARING CERTAIN PYRROLOTRIAZINE COMPOUNDS AND A PROCESS FOR MAKING THE INTERMEDIATES - The invention relates to 2,4-dibromoropyrrolo[1,2-f][1,2,4]triazine, which is an intermediate useful in preparing 2,4-disubstituted pyrrolotriazine compounds, and a process for preparing the intermediate. | 03-04-2010 |
20110071288 | INTERMEDIATE USEFUL IN PREPARING CERTAIN PYRROLOTRIAZINE COMPOUNDS AND A PROCESS FOR MAKING THE INTERMEDIATE - The invention relates to 2,4-dibromoropyrrolo[1,2-f][1,2,4]triazine, which is an intermediate useful in preparing 2,4-disubstituted pyrrolotriazine compounds, and a process for preparing the intermediate. | 03-24-2011 |
20120253041 | NEW PHENYLALANINE DERIVATIVES - Specified phenylalanine derivatives and analogues thereof have an antagonistic activity to α4 integrin. They are used as therapeutic agents for various diseases concerning α4 integrin. | 10-04-2012 |
20120264935 | SYNTHESIS OF LIGANDS FOR USE IN ACTINIDE EXTRACTION - The invention discloses an improved process for the preparation of 2,2,5,5-tetrasubstituted hexane-1,6-dicarbonyl compounds, and in particular diethyl 2,2,5,5-tetramethylhexanedioate and dimethyl 2,2,5,5-tetramethylhexanedioate, by the alkylation of 1,2-difunctional ethane compounds with enolates of carbonyl compounds. The process provides higher yields and greater synthetic brevity than existing processes. | 10-18-2012 |
20120302747 | PYRROLOTRIAZINE KINASE INHIBITORS - The invention provides compounds of formula I | 11-29-2012 |
20160159814 | GLYCINE TRANSPORTER INHIBITOR - The present invention provides novel compounds of formula [I] or pharmaceutically acceptable salts thereof: | 06-09-2016 |
544184000 | Four or more ring hetero atoms in the polycyclo ring system | 12 |
20090082564 | INK JET DYE DESIGN - Magenta chromophore dyes which are stabilized by adding steric hindering groups to protect the imino carbons; nonlimiting examples of the steric hindering groups being phenyl, methyl, ethyl, isopropyl, fluoride, chloride, bromide and iodide groups. | 03-26-2009 |
20100228027 | NOVEL COMPOUNDS OF REVERSE TURN MIMETICS AND THE USE THEREOF (2) - Conformationally constrained compounds that are novel and mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins and having bicyclic frame-work are disclosed, as well as their prodrugs. Such reverse-turn mimetic structures and prodrugs have utility over a wide range of fields, including use as diagnostic and therapeutic agents. The invention also relates to the use of such compounds for the preparation of a medicament for treating or preventing cancer including an acute myeloid leukemia. | 09-09-2010 |
20110028720 | New Coupling Agents for Peptide Synthesis - The present invention is directed to compounds of the formula: | 02-03-2011 |
20110172422 | Methods of Making Pharmacokinetically Improved Compounds Comprising Functional Residues or Groups and Pharmaceutical Compositions Comprising Said Compounds - The present invention relates to methods of modulating the pharmacokinetic and/or pharmacodynamic properties of a compound by attaching at least one functional unit or group to the compound, thereby improving its non-specific binding characteristics and/or pharmacokinetic properties. Compounds comprising at least one functional residue are provided, as are pharmaceutical compositions comprising said compounds. | 07-14-2011 |
20110190495 | N-BUTYRAMIDE, THE PREPARATION METHOD AND USE THEREOF - Disclosed are N-{1-[3-(2-ethoxy-5-(4-ethylpiperazinyl)sulfonylphenyl)-4,5-dihydro-5-oxo-1,2,4-triazin-6-yl]ethyl}butyramide (which is represented by formula III), its preparation method, intermediates during preparation procedure, preparation method for such intermediates and a method for preparing vardenafil from the compound. In the method for preparing vardenafil, a chloro-sulfonation reaction carries out in the early stage of the preparation procedure. | 08-04-2011 |
20110190496 | FUSED BICYCLIC mTOR INHIBITORS - Compounds represented by Formula (I) | 08-04-2011 |
20120190849 | PROCESSES FOR THE PREPARATION OF VARDENAFIL - The present invention provides processes for the preparation of vardenafil, its pharmaceutically acceptable salts, hydrates and intermediates. | 07-26-2012 |
20120277428 | NEW COUPLING AGENTS FOR PEPTIDE SYNTHESIS - The present invention is directed to compounds of the formula: | 11-01-2012 |
20130030174 | COMPOSITION FOR REDUCING SKIN WRINKLES INCLUDING PDE5 INHIBITOR - Disclosed is a composition effective in reducing skin wrinkles. The composition comprises or uses a phosphodiesterase 5 (PDE5) inhibitor as an active ingredient. Further disclosed is a method for reducing skin wrinkles using the composition. | 01-31-2013 |
20140066622 | Imidazo[5,1-f][1,2,4]Triazines For The Treatment of Neurological Disorders - The present invention relates to compounds of the Formula | 03-06-2014 |
20140148598 | IMIDAZOLE DERIVATIVE - An object of the present invention is to provide a compound that can regulate plant growth. The compound selected from the group consisting of (A) and (B): | 05-29-2014 |
20140330014 | IMIDAZOTRIAZINONE COMPOUNDS - The present invention provides imidazotriazinone compounds which are inhibitors of phosphodiesterase 9. The present invention further provides processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of PDE9 associated diseases or disorders in mammals, including humans. | 11-06-2014 |