Class / Patent application number | Description | Number of patent applications / Date published |
536055000 | Plural nitrogens containing | 26 |
20080249296 | Molecular Transporters Based on Sugar and Its Analogues and Processes For the Preparation Thereof - The inventive molecular transporter compound shows significantly high permeability through a biological membrane such as a plasma membrane, nuclear membrane and blood-brain barrier, and accordingly, can be effectively used in delivering various biologically active molecules. | 10-09-2008 |
20090292115 | PROCESSES FOR CHEMICAL SYNTHESIS OF LIPOCHITOOLIGOSACCHARIDES - Processes for the synthesis of lipochitooligosaccharides were developed. A fully acylated oligoglucosamine precursor is prepared and reacted with a glucosamine monomer that has an amine protecting phthaloyl group. With removal of the phthaloyl group, a fatty acid may be added on the terminal glucosamine unit, forming a lipochitooligosaccharide. The processes can be adapted for use on a commercial scale. | 11-26-2009 |
20110144321 | SYNTHETIC INTERMEDIATES AND PROCESSES - The invention provides novel synthetic intermediates and processes that can be used to prepare compounds of formula (I), wherein R | 06-16-2011 |
20130046088 | Processes for the Preparation of SGLT2 Inhibitors - Provided are processes for the preparation of complexes that are useful in purifying compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The processes can reduce the number of steps needed to obtain the target compounds and the complexes formed in the processes are typically provided in a crystalline form. | 02-21-2013 |
20140031540 | CRYSTALLINE COMPLEX OF 1-CYANO-2-(4-CYCLOPROPYL-BENZYL)-4-(SS- D-GLUCOPYRANOS-1-YL)-BENZENE, METHODS FOR ITS PREPARATION AND THE USE THEREOF FOR PREPARING MEDICAMENTS - The invention relates to a crystalline complex of 1-cyano-2-(4-cyclopropyl-benzyl)-4-(β-D-glucopyranos-1-yl)-benzene and a natural amino acid, to methods for the preparation thereof, as well as to uses thereof for preparing medicaments. | 01-30-2014 |
20150011747 | METHODS FOR MAKING BIOCOMPATIBLE POLYMERIZABLE ACRYLATE PRODUCTS - Sugar-acrylic monomers are synthesized to have a carbohydrate moiety linked to an acrylate group. The sugar-acrylic monomers may be polymerized to form polymers, adhesives, hydrogels, and the like. The sugar-acrylic monomers and polymers may be used in tissue engineering, adhesives and sealers, wound healing, and the like. | 01-08-2015 |
20150315339 | BINDER - The present invention relates to binder compositions with an improved amine component, and a method of manufacturing a collection of matter bound by said binder compositions. | 11-05-2015 |
536550100 | Polysaccharides | 19 |
20080287672 | Preserved compositions containing hyaluronic acid or a pharmaceutically-acceptable salt thereof and related methods - The invention provides a composition containing hyaluronic acid (HA) or a pharmaceutically-acceptable salt thereof preserved with a cationic preservative and related methods. In one embodiment, the pharmaceutically-acceptable salt is sodium hyaluronate. In another embodiment, the cationic preservative includes benzalkonium chloride (BAK). | 11-20-2008 |
20080312429 | Bismuth Hyaluronate, the Preparation Method and the Use Thereof - The present invention discloses a bismuth hyaluronate, characterized in that the bismuth content is from 0.5% to 40%, and the glucuronate content is from 20% to 45%, based on dry weight. Also provided is a method for the preparation of said bismuth hyaluronate comprising reaction of a soluble hyaluronate salt with a bismuth salt in a basic aqueous solution, followed by steps of precipitation, filtration, desalting, dehydrating and drying to obtain the product. Further disclosed is the use of the bismuth hyaluronate in the manufacture of a medicament or health foods for preventing and treating gastrointestinal disorders, in particular ulcerous disorders of the GI tract. It has been proven in animal experiments to show a better therapeutic effect than products of the same type. | 12-18-2008 |
20100010210 | Vaccine - The invention relates to a vaccine for the treatment of disease caused by | 01-14-2010 |
20110060139 | CARBOHYDRATE DERIVATIVES - A 1,2-dideoxy-1,2-diamino oligosaccharide or polysaccharide in its free base, salt or metal-complex form as shown in General Formula 1 and derivative thereof is described. | 03-10-2011 |
20110166339 | CRYSTALLINE CARBOHYDRATE DERIVATIVE - α-Lactosamine hydrochloride, substantially free of β-lactosamine hydrochloride; a method of preparing α-lactosamine hydrochloride monohydrate from an anomeric mixture of lactosamine hydrochloride, including: preparing a solution including the anomeric mixture of lactosamine hydrochloride, water and at least one water-miscible organic solvent at a temperature of 0-100° C., and cooling the solution to cause crystallisation of α-lactosamine hydrochloride monohydrate; a method of preparing anhydrous α-lactosamine hydrochloride; and use of α-lactosamine hydrochloride as a food supplement or intermediate in synthesis. | 07-07-2011 |
20110224423 | INOSITOL AND TREHALOSE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING NEURODEGENERATIVE DISEASES COMPRISING THE SAME - The invented inositol and trehalose derivatives, prepared by introducing multiple units of the guanidine group to the backbone molecules, show excellent blood-brain barrier permeability, and accordingly, it can be easily transported to the brain tissues and utilized for the treatment of neurodegenerative diseases such as Alzheimer's disease and Huntington's disease. | 09-15-2011 |
20120232262 | METHOD FOR PREPARING N-SUCCINIMIDYL N-BIOTINYL-6-AMINOCAPROATE - The invention relates to a method for preparing N-succinimidyl N-biotinyl-6-aminocaproate, characterised in that said method includes a step of activating N-biotinyl-6-aminocaproic acid in the form of a mixed anhydride, followed by coupling said mixed anhydride with N-hydroxysuccinimide. | 09-13-2012 |
20130096295 | Maltoside and Phosphocholine Derivatives, Uses thereof and Methods of Preparing Artificial Lipid Structures Thereof - Disclosed are saccharide and phosphocholine derivatives. The derivatives include azide and alkyne derivatives which form one end of a variable length carbon chain. The opposite end of the variable length carbon chain is covalently linked to the saccharide or phosphocholine. The saccharide may be, for instance, a maltoside. The alkyne and azide derivatives of the saccharides and phosphocholine may be reacted together to form amphiphilic molecules useful in cellular membrane studies and applications. By adjusting the length of the carbon chain, the biochemical and biophysical properties of the resultant 1,4-disubstituted 1,2,3-triazole compounds may be custom tailored for the intended application. Resultant molecules may form micelles, bicelle, lipid bilayers and other like structures useful in the isolation and purification of membrane bound or membrane associated proteins and biochemical components. The saccharides and phosphocholine molecules may be alternatively substituted as desired to provide additional flexibility in designing the desired end product. | 04-18-2013 |
20130116423 | Synthetic Oligosaccharides for Staphylococcus Vaccine - The present invention synthetic oligo-β-(1→6)-glucosamine structures and a methodology which essentially allows for the synthesis of any oligo-β-(1→6)-glucosamine species having a definite number of monosaccharide units, including a set pattern of acetylated and non-acetylated residues. The invention further provides antibodies to these synthetic oligo-β-(1→6)-glucosamines as well as compositions thereof and methods for treating and preventing infections caused by bacteria expressing poly-β-(1→6)-glucosamines, such as | 05-09-2013 |
20130231474 | POLYSACCHARIDE DERIVATIVES INCLUDING AN ALKENE UNIT AND THIOL-CLICK CHEMICAL COUPLING REACTION - The invention relates to polysaccharides grafted with a unit including a carbon-carbon double bond, to polysaccharides grafted with a unit including a carbon-carbon double bond functionalized by a thioether unit, to the methods for preparing said compounds, to the compositions including such compounds and to the materials including such materials or compositions. | 09-05-2013 |
20130338352 | DERIVATIVE OF HYALURONIC ACID MODIFIED WITH AMINO-CARBOXYLIC ACID - The present invention provides a hyaluronic acid derivative comprising disaccharide units of Formula (I), and a hyaluronic acid derivative/drug conjugate wherein one or more drugs are conjugated to the hyaluronic acid derivative. | 12-19-2013 |
20140011991 | PROCESS FOR PRODUCING WATER-SOLUBLE HYALURONIC ACID MODIFICATION - The present invention provides a water-soluble modified HA practically used as a drug carrier and a production method thereof. The present invention provides: a water-soluble modified hyaluronic acid, the residence time in blood of which is elongated to a practical level, which is produced by introducing a substituent into the carboxy group of the glucuronic acid of hyaluronic acid or a derivative thereof, via an amide bond, at a lower limit of an introduction ratio of 5 mole % or more, using a BOP condensing agent in an aprotic polar solvent; and a production method thereof. Moreover, by cross-linking the modified hyaluronic acid, the present invention provides a hyaluronic acid gel capable of extremely long drug sustained-release even at the same cross-linking functional group introduction ratio as that of the conventionally known gel. | 01-09-2014 |
20140051849 | HEMOSTATIC COMPOSITIONS AND THERAPEUTIC REGIMENS - The present invention relates generally to the field of hemostasis, including methods, compositions, and devices that can be employed to treat wounds. More specifically the present invention relates to hemostatic compositions that reduce the need for, and cost of, nursing care of patients with chronic wounds by reducing the frequency of wound dressing changes. | 02-20-2014 |
20140066617 | METHOD FOR PRODUCING SIALIC-ACID-CONTAINING SUGAR CHAIN - [Problem to be Solved] | 03-06-2014 |
20140179911 | METHODS AND MEANS FOR THE MANUFACTURE OF HYALURONAN - The present invention relates to plant cells and plants which synthesize hyaluronan and to methods for preparing such plants, and also to methods for preparing hyaluronan with the aid of these plant cells or plants. Furthermore, the present invention relates to the use of plants for preparing hyaluronan and to food or feed which comprises hyaluronan. | 06-26-2014 |
20150087821 | Benzimidazole Compounds And Their Use As Chromatographic Ligands - The present invention provides a new method for isolation and/or purification of immunoglobulins from a solution containing one or more immunoglobulins using a solid phase matrix represented by the formula: M-SP-L, wherein M is designates a matrix backbone, SP designates a spacer and L designates a substituted benzimidazole ligand. | 03-26-2015 |
20150291706 | Photoreactive Derivative of Hyaluronic Acid, Method of Preparation Thereof, 3D.Crosslinked Derivative of Hyaluronic Acid, Method of Preparation and Use Thereof - The subject-matter of the invention is a photoreactive derivative of hyaluronic acid (formula I) and the method of preparation thereof, where first an aldehyde derivative of hyaluronic acid is prepared, oxidized in the position 6 of the glucosamine cycle and then the oxidized derivative reacts with an amine carrying a photoreactive species, for example 1-(2-aminoethyl)pyridine-2(1H)-one, in the presence of a reducing agent, forming a photoreactive derivative. The prepared photoreactive derivative may be then photocrosslinked, wherein the reaction is based on [4+4] photocycloaddition. Moreover, the invention relates to a 3D-crosslinked derivative of hyaluronic acid (formula II) which exhibits an increased hydrolytic stability and improved sorption properties, with the possibility of a further design of the physical properties thereof according to the requirements of the final applications, and moreover, to the use thereof in tissue engineering, regenerative medicine, medical agents or formulations or cosmetics. | 10-15-2015 |
20160082150 | HYALURONIC ACID GELS CROSSLINKED BY SODIUM TRIMETAPHOSPHATE - Injectable dermal fillers including hyaluronic acid crosslinked with trimetaphosphate, and methods of making same are provided. | 03-24-2016 |
20160159937 | POLYSACCHARIDE DERIVATIVES INCLUDING AN ALKENE UNIT AND THIOL-CLICK CHEMICAL COUPLING REACTION - The invention relates to polysaccharides grafted with a unit including a carbon-carbon double bond, to polysaccharides grafted with a unit including a carbon-carbon double bond functionalized by a thioether unit, to the methods for preparing said compounds, to the compositions including such compounds and to the materials including such materials or compositions. | 06-09-2016 |