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Composition suitable for use as tissue or body member replacement, restorative, or implant

Subclass of:

523 - Synthetic resins or natural rubbers -- part of the class 520 series

523000000 - SYNTHETIC RESINS (CLASS 520, SUBCLASS 1)

523001000 - PROCESSES OF PREPARING A DESIRED OR INTENTIONAL COMPOSITION OF AT LEAST ONE NONREACTANT MATERIAL AND AT LEAST ONE SOLID POLYMER OR SPECIFIED INTERMEDIATE CONDENSATION PRODUCT, OR PRODUCT THEREOF

523105000 - Nonmedicated composition specifically intended for contact with living animal tissue or process of preparing; other than apparel

Patent class list (only not empty are listed)

Deeper subclasses:

Class / Patent application numberDescriptionNumber of patent applications / Date published
523115000 Composition suitable for use as tooth or bone replacement, restorative, or implant 163
523118000 Sealant or adhesive 47
523114000 Composition which anchors by ingrowth of surrounding tissue 4
20110288199Fiber-Hydrogel Composite for Tissue Replacement - The present invention includes tailored fiber-reinforced hydrogel composites for implantation into a subject. The present invention also includes systems and methods for controlling the relative percent volume of the hydrogel and fibers, cross-linking, fiber orientation, weave and density, such that the material properties of the composite can be controlled and/or customized to match particular tissue types. The composites of the present invention are suitable for repairing or replacing musculoskeletal tissues and/or fibrocartilage, such as the meniscus, ligaments and tendons.11-24-2011
20100010114Hydrophilic Interpenetrating Polymer Networks Derived From Hydrophobic Polymers - A composition of matter comprising a water-swellable IPN or semi-IPN including a hydrophobic thermoset or thermoplastic polymer and an ionic polymer, articles made from such composition and methods of using such articles. The invention also includes a process for producing a water-swellable IPN or semi-IPN from a hydrophobic thermoset or thermoplastic polymer including the steps of placing an ionizable monomer solution in contact with a solid form of the hydrophobic thermoset or thermoplastic polymer; diffusing the ionizable monomer solution into the hydrophobic thermoset or thermoplastic polymer; and polymerizing the ionizable monomers to form a ionic polymer inside the hydrophobic thermoset or thermoplastic polymer, thereby forming the IPN or semi-IPN.01-14-2010
20100280147High refractive index interpenetrating networks for ophthalmic applications - Ophthalmic devices are provided based on an interpenetrating (IPN) double network hydrogel of a first network physically entangled with a second network. The first network is an entangled network of self-linked hydrophilic telechelic macromonomers and hydrophobic moieties. The second network is a hydrophilic network of crosslinked polyacrylic acid. The IPN double network hydrogels including the hydrophobic moieties are characterized by being optically clear and having refractive indices above 1.34.11-04-2010
20110071233HARDENING COMPOSITION - A hardening composition comprising a particulate glass, said glass comprising 10-35% by weight of silica, 10-35% by weight of alumina, 3-30% by weight of zinc oxide, 4-30% by weight of P03-24-2011
Entries
DocumentTitleDate
20100063175Composition - A composition comprising polymer particles and a carrier, wherein the polymer particles are a mixture of at least a first polymer and a second polymer, wherein the first polymer is at least partially soluble or dispersible in the carrier, and wherein the polymer particles are arranged such that they can join together to form a scaffold of polymer particles, and wherein the composition is administrable to a human or non-human animal.03-11-2010
20120184642MULTIMODAL VISIBLE POLYMER EMBOLIZATION MATERIAL - The present invention relates to embolization material for therapeutic use, wherein said material is visible via more than one imaging technique.07-19-2012
20110196060NON-DEGRADABLE, LOW SWELLING, WATER SOLUBLE RADIOPAQUE HYDROGEL POLYMER - Hydrogel compositions prepared from amine components and glycidyl ether components are provided which are biocompatible and suitable for use in vivo due, in part, to their excellent stability.08-11-2011
20100076114POLYMERIC MATERIALS - An assembly comprises first and second parts which bear against one another, wherein said first part comprises a polyetherketone and said second part comprises a polyetherketone. The parts bear against one another such that one or both of the parts may have a tendency to wear and/or produce wear debris by virtue of contact between the parts. The materials used, however, minimise wear and the production of such wear debris.03-25-2010
20100076113COATING WITH ANTIMICROBIAL AGENTS - A coating with antimicrobial agents for use with medical devices. In one approach, a related method involves coating high temperature vulcanized silicone material with a room temperature vulcanized dispersion.03-25-2010
20130035415IN SITU BULKING COMPOSITION - The present invention relates to a hydrated, biocompatible tissue-augmentation compound and methodology for its implantation into mammalian tissue. The tissue-augmentation compound is comprised of: living tissue, optionally body derived fluids, and at least one NCO-terminated hydrophilic urethane prepolymer derived from an organic polyisocyanate, and oxyethylene-containing diols or polyols in which essentially all of hydroxyl groups are capped with polyisocyanate.02-07-2013
20100041788Implantation Compositions for Use in Tissue Augmentation - A composition of matter and method for preparation of a tissue augmentation material. A polysaccharide gel composition is prepared with rheological properties selected for a particular selected application. The method includes preparing a polymeric polysaccharide in a buffer to create a polymer solution or gel suspending properties in the gel and selecting a rheology profile for the desired tissue region.02-18-2010
20100105800BARRIER MEMBRANE - Cell-occlusive membrane, obtainable by reaction of at least two precursors in the presence of water. The first precursor A comprises a core and n chains each having a conjugated unsaturated group or a conjugated unsaturated bond, and the second precursor B comprises a core and m chains each having a thiol group, wherein m is greater than or equal to 2, n is greater than or equal to 2, and m+n is greater than or equal to 5. The reaction forms a three dimensional network with crosslinking-points. The adjacent crosslinking-points are connected by a chain having less than 600 atoms.04-29-2010
20100105799DEGRADABLE COMPOSITE - A degradable composite comprising a degradable matrix, a first fibre type and a second fibre type, wherein the first fibre type has a different rate of degradation to that of the second fibre type.04-29-2010
20090306245Implant Filling Material and Method - Compositions of cross-linked polyvinylpyrrolidone (PVP) are disclosed that are generally in the form of an elastic, hydrophilic, water-insoluble viscous cohesive mass of material that has many important medical uses including uses as a filler for implants. The present invention also involves a process for producing such compositions.12-10-2009
20120225972Poly (Diol Co-Citrate) Hydroxyapatite Composite for Tissue Engineering and Orthapaedic Fixation Devices - The present invention is directed to a novel poly (diol citrates)-based bioceramic composite materials created using completely biodegradable and a bioceramic material polymers that may be used in implantable devices. More specifically, the specification describes methods and compositions for making and using bioceramic composites comprised of citric acid copolymers and a bioceramic material.09-06-2012
20110021657HYDROPHILIC POLYURETHANE SOLUTIONS - The present invention relates to a coating compound comprising at least one polyurethane urea terminated with a copolymerized unit of polyethylene oxide and polypropylene oxide.01-27-2011
20080293844Gels - The present invention relates to silicon-containing biostable gels and processes for their preparation. The gels possess properties which make them useful in the manufacture and repair of biomaterials and medical devices, articles or implants, in particular the manufacture of soft tissue implants such as breast implants and the repair of orthopaedic joints such as spinal discs.11-27-2008
20110301259TEMPORAL INTRALUMINAL STENT, METHODS OF MAKING AND USING - A biodegradable polymer stent with radiopacity and a method of making and using a stent with enhanced mechanical strength and/or controlled degradation for use in a bodily lumen is described.12-08-2011
20100137471Compositions Containing Fast-Leaching Plasticizers For Improved Performance Of Medical Devices - Medical implants containing a temporary plasticizer, methods of producing such implants, and methods of using the implants in treating a disease, or ameliorating one or more symptoms thereof, in a subject are provided.06-03-2010
20080281016Polymer Composite - The invention provides a polymer composite comprising a thermoplastic host polymer having solid particulate material dispersed therethrough, the host polymer having at least one phase nanodomain, wherein the solid particulate material comprises particles having height, length and width dimensions of which at least one is substantially less than one or both of the other dimensions, and wherein the composite exhibits an increase in modulus of no more than 15% and a higher tensile strength, relative to said host polymer.11-13-2008
20080312356Vapor-deposited biocompatible coatings which adhere to various plastics and metal - A method of providing a biocompatible PEG-comprising coating on a substrate, without the use of an underlying adhesion layer. The coating is vapor deposited onto the substrate from a precursor which includes a PEG-derived moiety and an amino silane-containing functional group which reacts with the substrate. The substrate may be metal or plastic, where plastic excludes polyimide and polycarbonate. The substrate may be plasma treated prior to deposition of the PEG-comprising coating.12-18-2008
20090149568Biodegradable Coatings For Implantable Medical Devices - Biodegradable coatings for implantable medical devices are disclosed.06-11-2009
20090326094CUPS OF ARTIFICIAL CARDIAC VALVE AND METHOD FOR MANUFATURING THEREOF - The invention relates to medical technology and could be used in manufacturing artificial cardiac valves having one or more cusps made of a polymer composite. The method for manufacturing a cusp of an artificial cardiac valve, includes the steps of: manufacturing a casting mold, and molding a cusp from a polymer composite comprising 78 to 92% by weight of polyamide and 8 to 22% by weight of radiographic contrast medium dispersed therein. The polymer composite can comprise additionally fine acetylene black in amount of 1 to 2% by weight. The preferred radiographic contrast medium is barium sulphate. In one embodiment of the method, the casting mold is manufactured for the molding size 1 to 5% less than necessary, and the cusp is placed after molding into an anticoagulant solution and matured therein until expanding by 1 to 5%.12-31-2009
20110224325POLYETHYLENE CROSS-LINKED WITH AN ANTHOCYANIN - A method for manufacturing of ultrahigh molecular weight polyethylene (UHMWPE) for implants, where the implants have been machined out of UHMWPE blocks or extruded rods, has anthocyanin dispersely imbedded in the polyethylene. The implant is then exposed to γ ray or electron beam irradiation in an amount of at least 2.5 Mrad followed by a heat treatment to prevent the implant from becoming brittle in the long term as well as to improve strength and wear. The method includes mixing a powder or granulate resin of UHMWPE with an aqueous liquid that contains anthocyanin in a predetermined amount. The water is then evaporated in order to deposit the anthocyanin in a predetermined concentration on the polyethylene particles. The doped UHMWPE particles are compressed into blocks at temperatures in a range of approximately 135° C.-250° C. and pressures in a range of approximately 2-70 MPa. Medical implants are made from the blocks.09-15-2011
20090023835High Ion And Metabolite Flux Lenses And Materials - An exemplary embodiment provides a biocompatible polymer composition suitable for making intraocular lenses, especially posterior chamber phakic lenses, that includes a hydrogel having an equilibrium water content of less than about 55 wt. %. The hydrogel has a refractive index greater than about 1.41 and a sodium ion flux between about 16 to about 20 μeq-mm/hr/cm01-22-2009
20110230590POLYMERIC MATERIALS - Granules or pellets comprising polymeric materials such as polyaryletherketones and ceramic materials may be prepared and used to make a variety of different parts of components for use in medical applications, by melt-processing. The ceramic material may be a bioactive glass and/or a controlled-release glass, and may include less than 20 mole % sodium oxide and/or be water soluble.09-22-2011
20110060073Methods For Fabricating Polymer-Bioceramic Composite Implantable Medical Devices - Methods relating to polymer-bioceramic composite implantable medical devices are disclosed.03-10-2011
20090076188Polymer containing calcium sulfate particles for bone augmentation - Polymer containing calcium sulfate particles as an implant material are provided. The polymer containing calcium sulfate particles include a calcium sulfate compound coated with a therapeutic polymer containing salicylate, with a coating thickness from about 2 μm to about 50 μm. The therapeutic polymer in the particles is in a range from about 0.1% to about 22% (w/w). The resorption of the particles in vivo is from about four weeks to about twenty weeks. The polymer containing calcium sulfate particles can be used as an implant material for bone repairing and bone augmentation.03-19-2009
20110245367DEGRADABLE PHOTO-CROSSLINKER - Described herein is a degradable linking agent of formula Photo10-06-2011
20090312455Nanocomposites of repeat sequence proteins and phyllosilicate clays and their preparation - Nanocomposites of repeat sequence protein polymers and phyllosilicates demonstrated improved material properties, for example, improved elasticity, and are useful as suture, tissue scaffolding, and biodegradable composite materials.12-17-2009
20100210752PVA HYDROGELS HAVING IMPROVED CREEP RESISTANCE, LUBRICITY, AND TOUGHNESS - The invention provides creep resistant, lubricious and tough PV A-PAAm-hydrogels, creep resistant, lubricious, tough PVA-PAAm-hydrogel-containing compositions, and methods of making the same. The invention also provides methods of implanting or administering the creep resistant, lubricious and tough PV A-PAAm-hydrogels, or the PVAPAAm-hydrogel-containing compositions to treat a subject in need. Methods of cross-linking pre-solidified or pre-gelled hydrogel particles and making cross-linked PVA-PAAm-hydrogels, and cross-linked PVA-PAAm-hydrogel-containing compositions also are disclosed herein.08-19-2010
20100063174SYSTEMS AND METHODS FOR CONTROLLING AND FORMING POLYMER GELS - In preferred embodiments, the present invention provides methods of controllably making a vinyl polymer hydrogel having desired physical properties without chemical cross links or radiation. The gelation process is modulated by controlling, for example, the temperature of a resultant vinyl polymer mixture having a gellant or using active ingredients provided in an inactive gellant complex. In accordance with a preferred embodiment, the method of manufacturing a vinyl polymer hydrogel includes the steps of providing a vinyl polymer solution comprising a vinyl polymer dissolved in a first solvent; heating the vinyl polymer solution to a temperature elevated above the melting point of the physical associations of the vinyl polymer, mixing the vinyl polymer solution with a gellant, wherein the resulting mixture has a higher Flory interaction parameter than the vinyl polymer solution; inducing gelation of the mixture of vinyl polymer solution and gellant; and controlling the gelation rate to form a viscoelastic solution, wherein workability is maintained for a predetermined period, thereby making a vinyl polymer hydrogel having the desired physical property. In further preferred embodiments, the present invention provides physically crosslinked hydrogels produced by controlled gelation of viscoelastic solution wherein workability is maintained for a predetermined period. In another aspect, the present invention provides kits for use in repairing intervertebral disks or articulated joints including a dispenser and single use containers housing components that form the vinyl polymer hydrogel.03-11-2010
20100331444COMPOSITION CONTAINING UNSATURATED SILICONE COMPOUNDS, DENTAL MATERIALS CONTAINING THEM AND USE THEREOF - The invention relates to a curable composition comprising addition curable silicone component (A) having a linear siloxane backbone at least one unsaturated, non-activated side group pendant from the Si atom or atoms in the backbone, component (A) having an equivalent weight in the range of about 68 to about 1000, crosslinker component (B) comprising at least 2SiH groups, catalyst component (C) being able to catalyse the reaction between component (A) and component (B), filler component (D), wherein the equivalent weight is defined as (molecular weight of the molecule)/(number of unsaturations in the molecule).12-30-2010
20110257291Ophthalmic and Otorhinolaryngological Device Materials - Disclosed are soft, high refractive index, acrylic device materials. The materials contain a hydrophilic side-chain macromer for glistening resistance.10-20-2011
20110118379INTERVERTEBRAL DISC AND INTRAOCULAR LENS - The invention relates to the use of an aqueous gel in the repair of or prevention of damage to soft tissue, the gel comprising an aqueous gel obtainable by polymerizing one or more olefinically unsaturated monomers comprising one or more phosphate, phosphonate, borate, sulphate and/or sulphonate groups. This is preferably used for intervertebral discs or a lens of an eye. Kits and syringes containing the components are also provided.05-19-2011
20080293845Biodegradable Implant Polymers and Composites - Biodegradable oligomeric polyesters based upon hydroxy acids, such as glycolic acid (GA), lactic acid (LLA), and copolymers thereof are described. Composites that include biodegradable polyesters and bioabsorbable fillers are also described. The described polymers and composites are injectable and in situ curable.11-27-2008
20090012208Medical Device Having a Wetted Hydrophilic Coating - The present invention relates to a medical device having a wetted hydrophilic coating comprising: 01-08-2009
20100168270BIOCOMPATIBLE POLYCARBONATE AND RADIOPAQUE POLYMER COMPOSITIONS AND METHODS OF MANUFACTURING MEDICAL DEVICES WITH SAME - The invention relates to biocompatible polycarbonate/polyamide polymer compositions for use in medical and surgical devices. Additional additives, crosslinking agents, phosphites, and optionally a radiopaque filler or fillers can be used to produce the high performance compositions desired. The polymer compositions have improved melt processability along with balanced or enhanced physical and mechanical properties, especially when combined or over-extruded onto or covering other polymer layers, such as soft and/or flexible layers commonly used in medical device applications and catheter tips, for example. The ability to incorporate radiopaque compounds into these polymer compositions during melt processing offers improved methods for monitoring and visualizing medical devices when used inside the body and as well as improving the operating characteristics of the medical device components07-01-2010
20090076187High Refractive-Index, Hydrophilic Monomers and Polymers, and Ophthalmic Devices Comprising Such Polymers - An intraocular lens comprising a polymer that is prepared from a monomer mixture comprising a monomer of formula03-19-2009
20110009520DIMENSIONALLY STABLE, SHAPED ARTICLES COMPRISED OF DRIED, AGGREGATED, WATER-SWELLABLE HYDROGEL MICROSPHERES AND METHOD OF MAKING SAME - Dimensionally stable, shaped articles comprised of dried, aggregated, water-swellable hydrogel microspheres are described. The microspheres are aggregated together without the use of a binding agent. When exposed to an aqueous medium in a container, the dimensionally stable, shaped article swells slowly and disaggregates, forming at least partially swollen hydrogel microspheres, which take the shape of the container. The dimensionally stable, shaped articles disclosed herein have many potential applications, including medical applications such as a medical implant.01-13-2011
20110306699IN SITU FORMATION OF NANOPARTICLES IN RESINS - Methods of forming antimicrobial polymeric materials comprising metallic nanoparticles are disclosed. Such methods generally comprise: combining a metal-containing material with a resin in situ; and curing the resin in the presence of a metal-containing material. Antimicrobial polymeric materials formed by said methods are also disclosed.12-15-2011
20090093565Bio-polymer and scaffold-sheet method for tissue engineering - A method of making a new type of biomaterials, biodegrable crosslinked urethane-containing polyester (CUPE) elastomers and a scaffold-sheet engineering method for tissue engineering applications is provided. CUPEs can be synthesized by forming a linear pre-polymer, which is a polyester, introducing the urethane bonds into polyester using a diisocyanate as a linker, and crosslinking the resulting urethane containing linear polymers to form CUPEs via post-polymerization. This family of polymers, CUPEs, exhibit excellent biocompatibility with desired degradation. Tissue engineering scaffolds made of CUPEs are soft and elastic, and have good mechanical strength. Complex tissue grafts can be constructed by a novel layer-by-layer (LBL) scaffold-sheet engineering design using CUPE sheets. CUPE scaffolds can provide openings for cell to cell communication across scaffold layers and angiogenesis into the depth of the construct. Biomolecules, such as anticoagulants, can be incorporated into the CUPE polymers, increasing their viability as vascular graft scaffolds.04-09-2009
20090156709SOFT TISSUE FILLER - An improved non-toxic soft tissue filler is provided. The soft non-toxic tissue filler consists of textured surfaced spherically shaped solid particles of a size range of between about 32 and 90 microns (depending on the concentration that is desired) that are suspended evenly in a gel as a carrier. The solid particles are preferably a non-ceramic cured polymer such as polymethylmethacrylate (PMMA). The gel is a combination of a cellulose polysaccharide such as carboxymethylcellulose (CMC) and an alcohol such as polyvinyl alcohol (PVA) dissolved in water or some other solvent. The filler is used by injection in order to augment a patient's soft tissue as well as to correct soft tissue defects.06-18-2009
20120046383SILICONE RUBBER COMPOSITION - The silicone rubber composition disclosed here is formed a configuration in which vitamin E or a derivative thereof, or a salt of any one thereof is dispersed at least at a portion of the silicone rubber. Also disclosed is a method of manufacturing a medical apparatus that involves mixing a silicone rubber precursor with vitamin E or a derivative thereof, or a salt of any one thereof and hardening the obtained mixture, or a process of infiltrating a silicone rubber into vitamin E or a derivative thereof, or a salt of any one thereof in a liquid state. Further, the method of manufacturing a medical apparatus as disclosed here includes installing the obtained silicone rubber composition onto a medical apparatus; hermetically packaging the obtained medical apparatus; and irradiating radiation to the hermetically packaged medical apparatus.02-23-2012
20090149569SURFACE ENGINEERING OF TISSUE GRAFT MATERIALS FOR ENHANCED POROSITY AND CELL ADHESION - In one aspect, the invention relates to providing enhanced application tissue graft materials in regenerative medicine through improved cellular interactions. Biocompatible implant materials, methods for preparing biocompatible implant materials, methods for using same, and methods for treating tissue injury are disclosed. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.06-11-2009
20110166249POLYMERS HAVING LIPOPHILIC HYDROCARBON AND BIODEGRADABLE POLYMERIC SEGMENTS - The present invention pertains, among other things, to polymers having one or more lipophilic hydrocarbon segments and one or more biodegradable polymeric segments, to methods of making such polymers and to products formed using such polymers.07-07-2011
20110166250COPOLYMERS HAVING ZWITTERIONIC MOIETIES AND DIHYDROXYPHENYL MOIETIES AND MEDICAL DEVICES COATED WITH THE COPOLYMERS - Copolymers are manufactured to include a zwitterionic monomer (e.g., methacryloyloxyethyl phosphorylcholine monomer), a dihydroxyphenyl derivatized monomer, and optionally one or more additional monomers. The dihydroxyphenyl derivatized monomer gives the copolymers excellent adhesion properties. Optional monomers include a cationic amino monomer, a hydrocarbon monomer, and/or a hydrophilic monomer. The copolymers are biocompatible and can be used with medical devices.07-07-2011
20100234488USE OF PLASMA-SYNTHESISED PYRROLE-DERIVED POLYMERS FOR THE NEUROPROTECTION AND RECONNECTION OF THE CENTRAL NERVOUS SYSTEM - The purpose of the present invention is to demonstrate that semiconducting and non-biodegradable implants made with polypyrrole and polyethylenglycol copolymers and iodine-doped and plasma-synthesised pyrrole polymers, have a neuroprotector effect and induce the reconnection of the spinal cord after an injury; this effect was proved in a model involving a complete section of the spinal cord in rats; the results o the functional evaluation demonstrated 5 times greater recovery in animals implanted with the polypyrrole-polyethylenglycol copolymer compared with the control group which only underwent a complete section of the spinal cord; in addition, the functional recovery of the group with iodine-doped polypyrrole was ten times greater compared to the control group; in the histological study various inflammatory and immune cells were identified at the injury site in the three experimental groups with and without implants and the integration of the polymers in the nervous tissue of the spinal cord was also observed; finally, no respiratory, renal or skin infections, adverse effects or rejection of the biomaterials were found in any of the animals.09-16-2010
20120329905High Refractive Index Lenses - An optical copolymer comprising: a constituent derived from a sulfated lens monomer of general formula I12-27-2012
20120101185POLYMERIC MATERIALS COMPRISING BARIUM SULPHATE - The use of barium sulphate for increasing the impact strength of a polyaryletherketone and/or a polyarylethersulphone involves compounding the barium sulphate with the polymeric material and including water in the composition prepared. The material may be used in implantable prostheses.04-26-2012
20130178555POLYMERS FOR INTRAOCULAR LENSES - The present invention provides optic portions, intraocular lenses, and polymers for use in manufacturing optic portions and intraocular lenses. The optic portions include a polymer that comprises (a) one or more alkoxyalkyl methacrylate monomers and/or one or more alkoxyalkyl acrylate monomers that are incorporated in the polymer; (b) one or more hydroxyalkyl methacrylate monomers and/or one or more hydroxyalkyl acrylate monomers that are incorporated in the polymer; and (c) optionally, one or more crosslinking agents that are incorporated in the polymer.07-11-2013

Patent applications in class Composition suitable for use as tissue or body member replacement, restorative, or implant

Patent applications in all subclasses Composition suitable for use as tissue or body member replacement, restorative, or implant