Class / Patent application number | Description | Number of patent applications / Date published |
514517000 | S-X-C containing (e.g., sulfates, etc.) (X is chalcogen) | 35 |
20080207750 | Use of N-Chlorotaurine for Treatment of Oozing Tissue Deficiencies - A pharmaceutical composition containing N-chlorotaurine is administered to a mammal to treat oozing tissue deficiencies. | 08-28-2008 |
20090069419 | MASKED CARBOXYLATE NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE - Masked carboxylate neopentyl sulfonyl ester prodrugs of acamprosate, pharmaceutical compositions comprising such prodrugs, and methods of using such prodrugs and compositions thereof for treating diseases are disclosed. In particular, acamprosate prodrugs exhibiting enhanced oral bioavailability and methods of using acamprosate prodrugs to treat neurodegenerative disorders, psychotic disorders, mood disorders, anxiety disorders, somatoform disorders, movement disorders, substance abuse disorders, binge eating disorder, cortical spreading depression related disorders, tinnitus, sleeping disorders, multiple sclerosis, and pain are disclosed. | 03-12-2009 |
20090082440 | SIMPLE PANTOIC ACID ESTER NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE - Pantoic acid ester neopentyl sulfonyl ester prodrugs of acamprosate, pharmaceutical compositions comprising such prodrugs, and methods of using such prodrugs and compositions thereof for treating diseases are disclosed. In particular, acamprosate prodrugs exhibiting enhanced oral bioavailability and methods of using acamprosate prodrugs to treat neurodegenerative disorders, psychotic disorders, mood disorders, anxiety disorders, somatoform disorders, movement disorders, substance abuse disorders, binge eating disorder, cortical spreading depression related disorders, tinnitus, sleeping disorders, multiple sclerosis, and pain are disclosed. | 03-26-2009 |
20090082441 | DEUTERIUM-ENRICHED TESAGLITAZAR - The present application describes deuterium-enriched tesaglitazar, pharmaceutically acceptable salt forms thereof, and methods of treating using the same. | 03-26-2009 |
20090192220 | TREATMENT FOR SOLID TUMORS - A method for treating a solid tumor in a subject comprises administering to the subject an ACAT inhibitory compound or a prodrug thereof, for example avasimibe, wherein (a) the solid tumor is at least about 2 mm in diameter and (b) the compound or prodrug thereof is administered in an amount that is therapeutically effective, but ineffective to cause unacceptable toxicity to normoxic tissues. | 07-30-2009 |
20100035984 | Use of an antibacterial compound which is derived from alliaceae, as a natural additive in animal feed - The invention relates to the use of an antibacterial compound, which is derived from alliaceae, as a natural additive in animal feed, intended as an antimicrobial agent in animal feed, and as an alternative, due to its antibacterial nature, to the use of antibiotics as growth promoters, proposing the use of the compound separately (purity greater than 95%), and encapsulated or supported on different inert materials or food coatings, and in that said compound preferably consists of propyl propylthiosulfinate and, in an alternative variant, of propyl propylthiosulfonate. | 02-11-2010 |
20100240747 | Motuporamine Mimic Agents - Disclosed herein are motuporamine mimic agents and methods of making and using same. Particularly exemplified are motuporamine mimic agents comprising cytotoxic activity and/or anti-metaplastic activity. | 09-23-2010 |
20110105604 | MOISTURIZING AND CLEANSING COMPOSITION - An enhanced cleansing and moisturizing composition that uses strong cationic surfactants and strong anionic surfactants to deposit more moisturizers onto a user's skin. The improved cleansing and moisturizing composition, generally includes a water-soluble strong cationic surfactant, a water-soluble strong anionic surfactant, a polymeric surfactant, and an aqueous carrier. | 05-05-2011 |
20110190392 | Polysaccharide Based Antimicrobial Formulations - Described herein are antimicrobial formulations or compositions comprising an N-halogenated or N,N-dihalogenated amine compound and a saccharide-based gelling agent. Methods of using such formulations, including a method of preventing or treating an infection caused by a bacterial, a microbial, a sporal, a fungal or a viral activity, are also disclosed. | 08-04-2011 |
20110257263 | JASMONIC ACID COMPOUNDS IN COCOA PRODUCTS - The invention provides methods for isolating and enhancing the levels of jasmonates from cacao plant sources. In a preferred embodiment, jasmonic acid and 12-hydroxy jasmonate sulfate are detected in various cocoa products, and the levels of these compounds can be manipulated to increase the beneficial health effects of a food product made with the cocoa products The invention includes methods to prepare edible products containing cocoa jasmonates. | 10-20-2011 |
20120004302 | Cosmetic Use of N-Substituted Sulfonyloxybenzylamines and Related Compounds - Cosmetic compositions comprising N-substituted sulfonyloxybenzylamines and methods of using such compositions to impart anti-aging benefits to the skin are disclosed. The N-substituted sulfonyloxybenzylamines are believed to have modulatory activity against one or more biochemical pathways implicated in skin aging. | 01-05-2012 |
20120071553 | CHLORINE-FREE WATER TREATMENT - A combination of the surfactant SDS with levulinic acid produces a synergistic effect in relation to the antimicrobial effectiveness of the individual compounds, allowing the formulation of compositions wherein the active agents are present at concentrations effective to reduce bacterial and fungal counts in liquids, including, but not limited to, water and other beverages, without altering the organoleptic properties of the treated food substance. The active agents are FDA-approved as food additives, and the treated beverages can be any aqueous-based beverage consumable by humans or animals. The levulinic acid-SDS combination is also suitable for reducing or eliminating the microbial population on the surfaces of water and beverage containers, and the machinery and facilities for the bottling of liquids. | 03-22-2012 |
20120088828 | HIGH SURFACE ACTIVITY PESTICIDES - The present disclosure relates generally to the field of pesticides. In particular, the present disclosure relates to pesticide compositions that include high surface activity and slower drying surfactant pesticides. | 04-12-2012 |
20120129928 | Chlorine-Free Liquid Microbicide Treatment - The combination of the surfactant SDS with levulinic acid produces a synergistic effect in relation to the antimicrobial effectiveness of the individual compounds. Accordingly, this surprising synergy allows the formulation of compositions wherein the active agents are present at concentrations effective to reduce bacterial counts in liquids, including, but not limited to, water and other beverages, especially those having a pH value less than about 7.0 by a factor between 10 | 05-24-2012 |
20120136051 | RHEOLOGY MODIFIED LOW FOAMING LIQUID ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF - The present disclosure relates to rheology modified, low foaming aqueous antimicrobial compositions. The compositions are phase stable under acidic conditions, and do not need to be rinsed from the surface to which they are applied. The present disclosure further relates to methods of use thereof. | 05-31-2012 |
20120270939 | FORMULATIONS AND METHODS FOR TREATING AMYLOIDOSIS - Methods, formulations, and compositions for the treatment of amyloidosis are described. | 10-25-2012 |
20130059908 | SULFONAMIDES FOR THE PREVENTION OF DIABETES - The use of sulfonamides of formula (I) wherein R and R | 03-07-2013 |
20130059909 | Cinnamaldehyde-Allicin Formulations and Methods of Their Use - The invention is directed to emulsifiable oil suspension concentrate formulations containing cinnamaldehyde (cinnamic aldehyde) and allicin that are effective in protecting plants from pests, especially nematodes, and methods of their use. | 03-07-2013 |
20130079402 | Use of at Least One Dialkyl Thiosulfonate or Thiosulfinate for Reducing the Number of Apicomplexa in an Animal - The invention relates to the use of at least one dialkyl thiosulfonate or thiosulfinate in order to reduce the number of apicomplexa, such as coccidioides and, in particular, | 03-28-2013 |
20130090380 | NON-AEROSOL FOAMING ALCOHOL HAND SANITIZER - A non-aerosol, foaming high alcohol content hand sanitizer is provided which has excellent antimicrobial activity and tolerance for organic load and excellent residual activity, as well as enhanced moisturization and skin-feel properties over currently marketed alcohol-based sanitizers. The inventive composition achieves an unexpectedly large amount of quality, stable foam even in the presence of significant quantities of skin conditioning agents through the use of novel silicone surfactants and achieves enhanced and prolonged antimicrobial efficacy through the combination of high alcohol content and activity enhancing components. | 04-11-2013 |
20130253053 | Method of Treating Skin with microRNA Modulators - Methods for preventing, ameliorating, or reducing dermatological signs of aging are provided which employ active agents that suppress or down-regulate microRNA expression in dermal fibroblast, resulting in enhanced production of collagen, elastin and/or fibrillin in the skin. Also provided are methods for screening for activity against specific microRNAs and the methods of using active agents identified by the screening protocol in the treatment of skin. | 09-26-2013 |
20130310453 | GREEN GARLIC AND METHODS OF PRODUCTION - A new vegetable, referred to herein as green garlic, grown from garlic bulbils is disclosed. In particular examples, the green garlic is rich in one or more thiosulfinates. Methods of producing green garlic are also disclosed. In some examples, such methods permit year-round commercial production of green garlic. | 11-21-2013 |
20140121268 | Personal Care Compositions - A personal care composition exhibiting a tan delta of about 0.30 or more at about 10° C. includes a primary surfactant, secondary surfactant, and a polyol. Methods are also provided to improve the stability of a personal care composition. | 05-01-2014 |
20150148415 | DERIVATIZED DENDRIMER WITH LOW CITOTOXICITY FOR IN VIVO, EX VIVO, IN VITRO OR IN SITU CHELATION OF HEAVY METALS OR ACTINIDES - The present invention considers derivatized nanomolecules with proven effectiveness to bind to actinides, more specifically uranium, during in vivo, ex vivo, in vitro or in situ assays. When assayed in vivo, the invention showed a reduction in at least kidney damage due to exposition to uranium. | 05-28-2015 |
20160100577 | NATURALLY-DERIVED SURFACE SANITIZER AND DISINFECTANT - Food processing equipment, food contact surfaces, and non-food contact surfaces are sanitized or disinfected using an acid-anionic surfactant solution that has efficacy in hard water, is non-corrosive, and is stable at elevated temperatures. The sanitizing/disinfecting solution is prepared as a highly concentrated liquid and diluted to end use concentrations prior to application to food processing equipment or food or non-food contact surfaces. Efficacy in hard water is important for sanitizers and disinfectants that are diluted by the end user using potentially hard water. Stability at elevated temperatures is important for long-term storage and transportation. The diluted sanitizing/disinfecting solution exhibits strong antimicrobial activity against gram positive and gram negative bacteria even when diluted in hard water. The sanitizing/disinfecting solution exhibits low toxicity to humans and the environment since it is prepared from low toxicity ingredients that are readily biodegradable. | 04-14-2016 |
20160151324 | IMPROVEMENTS IN OR RELATING TO ALLIUM EXTRACTS | 06-02-2016 |
20160183525 | METHODS OF PREVENTING THE TRANSMISSION OF COMMUNICABLE DISEASES IN LIVESTOCK - A composition that includes ethylhexyl sulfate or a salt thereof, an alkylbenzenesulfonic acid or a salt thereof, and a carrier. The composition can be used for killing or inhibiting a microorganism or pathogen (e.g., bacteria, gram-negative bacteria, gram-positive bacteria, enteric bacteria, virus, fungus, mold, mildew or powdery mildew), located on a topical surface of an animal, located on a surface of an object that will contact a topical surface of an animal, or a combination thereof, wherein the microorganism or pathogen is associated with the transmission of communicable diseases. | 06-30-2016 |
20160199497 | Cholesterol Ester-Depleting Nanomedicine for Non-toxic Cancer Chemotherapy | 07-14-2016 |
514518000 | S of S-X-C attached directly to a benzene ring | 7 |
20090069420 | Small molecule inhibitors of STAT3 with anti-tumor activity - The present invention concerns compounds, compositions containing these compounds, and methods of using these compounds and compositions as inhibitors of Stat3 signaling, Stat3 dimerization, Stat3-DNA binding, Stat5-DNA binding, and/or aberrant cell growth in vitro or in vivo, e.g., as anti-cancer agents for treatment of cancer, such as breast cancer. The compounds of the invention include, but are not limited to, NSC 74859 (S3I-201), NSC 42067, NSC 59263, NSC 75912, NSC 11421, NSC 91529, NSC 263435, and pharmaceutically acceptable salts and analogs of the foregoing. Other non-malignant diseases characterized by proliferation of cells that may be treated using the compounds of the invention, but are not limited to, cirrhosis of the liver; graft rejection; restenosis; and disorders characterized by a proliferation of T cells such as autoimmune diseases, e.g., type 1 diabetes, lupus and multiple sclerosis. The invention further includes an in-vitro screening test for the presence of malignant cells in a mammalian tissue; a method of identifying inhibitors of constitutive Stat3 activation, Stat3-DNA binding, Stat5-DNA binding, and/or Stat3 dimerization; and a method of identifying anti-cancer agents. | 03-12-2009 |
20100234456 | APOPTOSIS PROMOTERS - Compounds which inhibit the activity of anti-apoptotic Mcl-1 protein, compositions containing the compounds and methods of treating diseases during which are expressed the Mcl-1 protein are disclosed. | 09-16-2010 |
20110166223 | METHODS OF INHIBITING FGFR3 SIGNALING - Novel inhibitors of FGFR3 signaling having a structure shown as Formula 1 and a method of inhibiting FGFR3 signaling by administering a quantity of the inhibitor, or pharmaceutical equivalent, analog and/or salt thereof, to a mammal are disclosed. Additionally, the inhibitor may be used for treating one or more conditions associated with FGFR3 mediated signaling | 07-07-2011 |
20110257264 | USE OF 2,5-DIHYDROXYBENZENE DERIVATIVES FOR TREATING ACTINIC KERATOSIS - The present invention relates to the use of a 2,5-dihydroxybenzene derivative represented by Formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the therapeutic and/or prophylactic treatment of, inter alia, actinic keratosis. | 10-20-2011 |
20140088191 | Inhibition of Renal Fibrosis - The invention provides compositions and methods for inhibiting renal fibrosis. | 03-27-2014 |
20140221477 | Process For The Preparation Of A Sulfated Derivative Of 3,5-Diiodo-O-[3-Iodophenyl]-L-Tyrosine - The present invention relates to a process for the preparation of the mono sodium salt of the derivative 3,5-diiodo-O-[3-iodo-4-(sulphooxy)phenyl]-L-tyrosine (T3S) by starting from the corresponding phenolic compound, in the presence of chlorosulfonic acid and dimethylacetamide as a solvent. The so obtained T3S compound may conveniently be isolated in a pure form as a solid in good yields. The present invention further relates to the process for T3S preparation, wherein the starting reagent is T2 and further comprising the formulation of such compound in tablets. Furthermore, the invention discloses non-radioactive immunoassays based on T3S derivatives. | 08-07-2014 |
20140329900 | SMALL MOLECULE INHIBITORS OF STAT3 WITH ANTI-TUMOR ACTIVITY - The present invention concerns compounds, compositions containing these compounds, and methods of using these compounds and compositions as inhibitors of Stat3 signaling, Stat3 dimerization, Stat3-DNA binding, Stat5-DNA binding, and/or aberrant cell growth in vitro or in vivo, e.g., as anti-cancer agents for treatment of cancer, such as breast cancer. The compounds of the invention include, but are not limited to, NSC 74859 (S31-201), NSC 42067, NSC 59263, NSC 75912, NSC 11421, NSC 91529, NSC 263435, and pharmaceutically acceptable salts and analogs of the foregoing. Other non-malignant diseases characterized by proliferation of cells that may be treated using the compounds of the invention, but are not limited to, cirrhosis of the liver; graft rejection; restenosis; and disorders characterized by a proliferation of T cells such as autoimmune diseases, e.g., type 1 diabetes, lupus and multiple sclerosis. The invention further includes an in-vitro screening test for the presence of malignant cells in a mammalian tissue; a method of identifying inhibitors of constitutive Stat3 activation, Stat3-DNA binding, Stat5-DNA binding, and/or Stat3 dimerization; and a method of identifying anti-cancer agents. | 11-06-2014 |