Class / Patent application number | Description | Number of patent applications / Date published |
514512000 | X-C(=X)-X containing (e.g., carbonic acid ester, thiocarbonic acid ester, etc.) (X is chalcogen) | 17 |
20090005444 | USE OF PROPOFOL PRODRUGS FOR TREATING ALCOHOL WITHDRAWAL, CENTRAL PAIN, ANXIETY OR PRURITUS - Methods of treating alcohol withdrawal, central pain, anxiety, or pruritus in a patient comprising orally administering a therapeutically effective amount of a propofol prodrug having high oral bioavailability are disclosed. | 01-01-2009 |
20090076141 | Use of Propofol Prodrugs for Treating Neuropathic Pain - Methods of treating alcohol neuropathic pain in a patient comprising orally administering a therapeutically effective amount of a propofol prodrug having high oral bioavailability are disclosed. | 03-19-2009 |
20090149533 | NOVEL FENOFIBRATE FORMULATIONS AND RELATED METHODS OF TREATMENT - The invention provides novel omega-3 ester-based oil solutions of fenofibrate. These solutions are substantially free of any food effect, effective in small volumes, and readily bioavailable. Notably, because the solutions of the invention contain an omega-3 ester-based oil as the major ingredient, they not only provide an antihyperlipidemic effect due to the fenofibrate active ingredient, they also provide recommended daily dosages of omega-3 oils (i.e., approximately 1 gram of omega-3 oil per day), or a portion thereof. | 06-11-2009 |
20090203776 | METHODS OF USING MENTHOL PROPYLENEGLYCOL-CARBONATE AND ANALOGS THEREOF FOR PRODUCING ANTI-INFLAMMATORY AND ANTI-ANGIOGENIC EFFECTS - Menthol propyleneglycal-carbonate, analogs thereof and compositions containing such compounds are administered to mammals, preferably humans, to produce anti-inflammatory or anti-angiogenic effects. | 08-13-2009 |
20100048699 | CHEMICAL COMPOUNDS - A compound of formula I | 02-25-2010 |
20100273875 | Composition for External Application to Skin - A composition for external application to skin, containing a compound represented by formula (I) or a salt thereof, and/or a quaternary ammonium salt represented by formula (II): | 10-28-2010 |
20110028544 | CATECHOL PROTECTED LEVODOPA DIESTER PRODRUGS, COMPOSITIONS, AND METHODS OF USE - Catechol protected levodopa diester prodrugs pharmaceutical, compositions comprising catechol protected levodopa diester prodrugs, and methods of using such prodrugs and pharmaceutical compositions for treating diseases such as Parkinson's disease are provided. | 02-03-2011 |
20110184061 | THIOCOLCHICINE AND COLCHICINE ANALOGS, METHODS OF MAKING AND METHODS OF USE THEREOF - Disclosed herein are thiocolchicine and colchicine analogs and derivatives suitable for use as a muscle relaxant, an anti-inflammatory agent, an anti-gout agent, an anti-proliferative agent, or an anti-cancer agent; methods of making the compounds, and compositions comprising the compounds. | 07-28-2011 |
20110294879 | METHOD OF TREATMENT OF FRAGILE X SYNDROME, DOWN'S SYNDROME, AUTISM AND RELATED DISORDERS - Disclosed herein are methods of treating fragile X syndrome, fragile X-associated tremor/ataxia syndrome, Down's syndrome and/or autism, comprising administering a prodrug of acamprosate to a subject suffering therefrom, wherein, in certain embodiments, the acamprosate prodrugs comprise compounds of Formula (I). | 12-01-2011 |
20120059056 | CARBONATE DERIVATIVES AS SKIN CARE - Carbonates of anti-aging ingredients, in particular anti-oxidants and skin illuminating phenol ingredients, have been prepared as derivatives of these ingredients with enhanced physical properties. It has been demonstrated that these carbonates will hydrolyze under enzymatic catalysis to release the parent ingredient. In contrast, esters of the phenolic groups in many cases do not hydrolyze under the same conditions. | 03-08-2012 |
20120149769 | Thiocarbonates as Anti-Inflammatory and Antioxidant Compounds Useful For Treating Metabolic Disorders - The invention is directed to thiocarbonate compounds of Formula (I)-(III) and methods of treating atherosclerosis, neuropathy, nephropathy, retinopathy, inflammatory disorders, COPD, cardiovascular diseases, metabolic disorders, type I diabetes mellitus, type II diabetes mellitus, LADA, Wolfram Syndrome 1, Wolcott-Rallison syndrome, metabolic syndrome, dyslipidemia, hyperglycemia, or insulin resistance. The compounds of the invention are also useful for protecting pancreatic beta-cells and for reducing free fatty acids, triglycerides, advanced glycated end products, ROS, lipid peroxidation, tissue and plasma TNFalpha and IL6 levels, or for delaying or preventing cardiovascular complications associated with atherosclerosis. | 06-14-2012 |
20120157523 | PRODRUGS OF METHYL HYDROGEN FUMARATE, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE - Prodrugs of methyl hydrogen fumarate, pharmaceutical compositions comprising prodrugs of methyl hydrogen fumarate, and methods of using prodrugs of methyl hydrogen fumarate and pharmaceutical compositions thereof for treating diseases such as psoriasis, asthma, multiple sclerosis, inflammatory bowel disease, and arthritis are disclosed. | 06-21-2012 |
20120302634 | SKIN PROTECTION COMPOSITIONS, IN PARTICULAR CREAM TO PROTECT AGAINST COLD - The invention relates to a silicone-free skin protection composition, in particular a composition to protect against cold, containing the components
| 11-29-2012 |
20130116319 | Agent for Treating Parkinson's Disease - The present invention relates to the use of 3-methyl-6-(1-methylethenyl)cyclohex-3-ene-1,2-diol, its isomers and derivatives, as a compound for Parkinson disease treatment, that can be used in medicine. The compound is highly active, low toxic and can be synthesized from available natural compound α-pinene. | 05-09-2013 |
20150119461 | TETRAHYDRO-ISOHUMULONE DERIVATIVES, METHODS OF MAKING AND USING - The present application provides novel tetrahydro-isohumulone (THIAA) derivatives and substantially enantiomerically pure compositions and pharmaceutical formulations thereof. The application further provides methods of using the disclosed compounds and compositions to activate PPARγ, inhibit inflammation, and treat conditions associated with inflammation and conditions responsive to PPARγ modulation such as diabetes. | 04-30-2015 |
20160090351 | INHIBITORS OF DEUBIQUITINATING PROTEASES - Disclosed are small molecule inhibitors of deubiquitinating enzymes (DUBs), and methods of using them. Certain compounds display a preference for specific ubiquitin specific proteases (USPs). | 03-31-2016 |
20160120778 | CLEANSING COMPOSITIONS - A personal care composition including at least one dry emollient and one oily emollient, where the personal care composition is free of silicone or silicone containing materials. | 05-05-2016 |