Entries |
Document | Title | Date |
20100234454 | TREATMENT OF CNIDARIA INTOXICATION - The present invention relates to the use of vanilloid receptor (VR) antagonists, and more particularly vanilloid receptor 1 (VR1) antagonist, as analgesics in the treatment and/or prohylaxis of cnidaria envenomations. | 09-16-2010 |
20110046217 | USE OF 2,2'-CYCLOLIGNANS FOR INDUCING, RESTORING OR STIMULATING THE PIGMENTATION OF THE SKIN, HAIR OR HAIRS - The invention relates to the use of 2,2′-cyclolignanes in the cosmetic or pharmaceutical field for inducing, restoring or stimulating the pigmentation of the skin, hair or hairs. | 02-24-2011 |
20110054015 | SOLID FORMS OF ORTATAXEL - The present invention relates to solid forms of 13-(N-Boc-β-isobutylserinyl)-14-β-hydroxybaccatin III 1,14-carbonate (Ortataxel). Amorphous Form A, crystalline Form B, mixtures thereof and processes for preparing them are disclosed. Amorphous Form A is prepared by fast precipitation of Ortataxel from a mixture of acetone and water. Form A transforms in Form B when suspended and stirred in a mixture of ethanol and water for 4-8 hours. If the suspension is stirred for less than 4 hours, mixtures of Form B and Form A are obtained. Form B or mixtures of Forms A and B can also be obtained dissolving Ortataxel in a protic organic solvent, followed by addition of water. | 03-03-2011 |
20110213026 | EXTRACTS WITH LIVER-X-RECEPTOR MODULATORS, COMPOUNDS AND THEIR USE ESPECIALLY IN WEIGHT CONTROL - The invention relates to the use, or methods (especially with regard to animals, especially human, that are in need of such treatment) comprising the use, of an extract and/or one or more natural compounds from plants or parts of plants, respectively, from a genus selected from the group consisting of | 09-01-2011 |
20110288166 | TRIPTOLIDE C-RING DERIVATIVES AS ANTICANCER AGENTS AND IMMUNE MODULATORS - Disclosed are compounds based on C- and D-ring modifications of triptolide and hydroxylated triptolide, for use in therapy, such as antiproliferative, anticancer, and immunosuppressive therapy. | 11-24-2011 |
20120225934 | INCLUSION COMPLEX OF DEOXYPODOPHYLLOTOXIN OF CYCLODEXTRIN, PREPARATION METHOD, USE FOR TREATMENT OF CANCER THEREOF - Inclusion complex of deoxypodophyllotoxin of cyclodextrin, the preparation method and the use for the treatment of cancer thereof are disclosed. The inclusion complex consists of deoxypodophyllotoxin and beta-cyclodextrin derivative, wherein the molar ration of deoxypodophyllotoxin to beta-cyclodextrin derivative is 1:1-1:10. The beta-cyclodextrin derivative is sulfobutyl ether-beta-cyclodextrin or hydroxypropyl-beta-cyclodextrin. | 09-06-2012 |
20130143959 | EXTRACTS WITH LIVER-X-RECEPTOR MODULATORS, COMPOUNDS AND THEIR USE ESPECIALLY IN WEIGHT CONTROL - The invention relates to an extract and/or one or more natural compounds from plants or parts of plants, respectively, from a genus selected from | 06-06-2013 |
20130225672 | SUBSTITUTED 4-BETA-ACRYLAMIDOPODOPHYLLOTOXIN CONGENERS AS ANTITUMOUR ANTIBIOTICS AND THE PROCESS FOR PREPARATION THEREOF - The present invention provides compounds of general formula (3) as useful potential antitumour agents against human cancer cell lines. The present invention further provides a process for the synthesis of 4β-acrylamidopodophyllotoxin congeners of general formula (3), wherein R and R1 are an aryl group and R is selected from 3,4,5-trimethoxyphenyl or 2-methoxy phenyl and R1 is selected from the group consisting of 4-hydroxy-3-methoxyphenyl, 3-hydroxy-4-methoxyphenyl, 4-fluoro-3-methoxyphenyl, 3-fluoro-4-methoxyphenyl, 2-fluoro-5-methoxyphenyl, 2-fluoro-4-methoxyphenyl, 4-hydroxy-3-nitrophenyl, 4-methoxy-3-nitrophenyl, 4-nitrophenyl, 3-nitrophenyl, 2-nitro phenyl, 4-methoxyphenyl, 3-methoxyphenyl and 4-hydroxyphenyl. | 08-29-2013 |
20130317099 | Picropodophyllin Polymorphs B or C for Use in Cancer Therapy - The invention relates to novel polymorphs of picropodophyllin, methods for preparing said polymorphs and pharmaceutical compositions comprising said polymorphs, as well as the use of said polymorphs in therapy such as cancer therapy. | 11-28-2013 |
20130331445 | Picropodophyllin Monohydrate or Polymorph A in Cancer Therapy - The invention related to picropodophyllin monohydrate as well as to picropodophyllin polymorph A for use in therapy, such as their use in cancer therapy. | 12-12-2013 |
20140128459 | SOLID FORMS OF ORTATAXEL - The present invention relates to solid forms of 13-(N-Boc-β-isobutylserinyl)-14-βhydroxybaccatin III 1, 14-carbonate (Ortataxel). Amorphous Form A, crystalline Form B, mixtures thereof and processes for preparing them are disclosed. Amorphous Form A is prepared by fast precipitation of Ortataxel from a mixture of acetone and water. Form A transforms in Form B when suspended and stirred in a mixture of ethanol and water for 4-8 hours. If the suspension is stirred for less than 4 hours, mixtures of Form B and Form A are obtained. Form B or mixtures of Forms A and B can also be obtained dissolving Ortataxel in a protic organic solvent, followed by addition of water. | 05-08-2014 |
20140142173 | PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF A NEURODEGENERATIVE DISEASE, COMPRISING A DAPHNE GENKWA EXTRACT OR A COMPOUND ISOLATED THEREFROM - The present invention relates to: a pharmaceutical composition or a Nurr1 activating composition for the prevention or treatment of a neurodegenerative disease or a disease induced by impaired Nurr1 function, wherein the composition comprises an active ingredient in the form of genkwanin N or yuanhuacine, a | 05-22-2014 |
20150031759 | Analogues of (-)Picropodophyllin, Synthesis And Uses Thereof - Compounds, compositions, methods of making, and methods of using analogues of (−)-picropodophyllin, as well as a transgenic animal model and its use for identifying anticancer agents. | 01-29-2015 |
20150045425 | PELTATIN AND METABOLIC DISORDERS - The present invention relates to the field of metabolic disorders and aims to identify natural compounds that can be used effectively in this field. In particular, the present invention provides a composition comprising at least one peltatin for use in the treatment or prevention of metabolic disorders or risk factors thereof. | 02-12-2015 |
20150057344 | PELTATIN FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISORDERS - The present invention generally relates to health benefits of natural compounds. In particular, the present invention relates peltatins, a group of natural compounds that can be used to treat, prevent or alleviate chronic inflammatory disorders. For example, the present invention concerns a composition comprising at least one peltatin for use in the treatment or prevention of chronic inflammatory disorders. | 02-26-2015 |
20150313870 | LOW DOSE TOPIRAMATE / PHENTERMINE COMPOSITION AND METHODS OF USE THEREOF - A method for effecting weight loss by administering a combination of topiramate and phentermine is provided. The phentermine is generally administered in immediate release form, in a daily dose in the range of 2 mg to 8 mg, in combination with a daily dose of topiramate selected to prevent the loss of effectiveness of phentermine alone. Methods for treating obesity, conditions associated with obesity, and other indications are also provided, as are compositions and dosage forms containing low doses of phentermine and topiramate, e.g., 3.75 mg phentermine and 23 mg topiramate. | 11-05-2015 |
20150335562 | Method of Treating or Reducing the Severity of Dermatological Conditions - The present disclosure provides compositions and methods for treating dermatological disorders using a podophyllotoxin formulation. | 11-26-2015 |
20150344411 | Catalytic Method for Dibenzocycloheptane Synthesis and Allocolchicinoid Synthesis - In a non-limiting embodiment, there is provided a compound of formula (I), which may permit for a method or use in treating or preventing a cancer, such as pancreatic cancer or leukemia. In one embodiment, there is also provide a method of preparing a compound of formula (Ia), the method including conducting a cyclization reaction of a compound of formula (III) to obtain a compound of formula (IV), wherein conducting the cyclization reaction comprises conducting a Michael reaction in the presence of a Lewis acid. | 12-03-2015 |
20150366839 | Schisantherin A for the treatment of neurodegenerative diseases - This invention is directed to the use of Schisantherin A or Schizandrin C in treating and/preventing neurodegenerative diseases. | 12-24-2015 |