Class / Patent application number | Description | Number of patent applications / Date published |
514462000 | Spiro ring system | 29 |
20080200539 | Topical antifungal treatment - The present invention is a topical skin preparation for treatment of fungal infections of the skin and nails. The preparation comprises triacetin in combination with one or more antifungal agents. In a preferred form, the preparation comprises a combination of the antifungal agents tolnaftate and grisiofulvin are used in combination with triacetin. The concentrations of these constituents are 40 to 50% concentration triacetin, 30 to 50% acetone, 0.5-3.0% concentration tolnaftate and 0.5-4.0% concentration grisiofulvin, in one preferred embodiment. Other compounds, such as ethyl alcohol, acetone, amino acids such as n-acetylcysteine, and herbal additives may also be added to the preparation. Further, other antifungal agents such as nystatin, clortimazole, econazole, ketoconazole, miconazole, solconazole, oxiconizole, naftifine, terbinafine, and butenafine, for example, may be substituted for the antifungal agents tolnaftate and grisiofulvin. The preparation of the present invention is effective in treating immune compromised patients and those with diabetes, as well as relatively healthy persons. | 08-21-2008 |
20080227855 | Solid Dispersion of Hydrophobic Bioactive - A stable composition of an amorphous component (such as a bioactive) and a carrier polymer is formed by mixing a bridging polymer with the bioactive and the carrier polymer, wherein the bridging polymer is a hydrogen bond donor to both the bioactive and the carrier polymer, thereby forming a composition in which the bioactive and the carrier polymer have less of a tendency to crystallise than if the bridging polymer were not present. | 09-18-2008 |
20090118362 | CHEMOTHERAPEUTIC AGENTS FOR INHIBITION OF PROTEIN TRANSLATION - The present invention relates to a anti-proliferative target for designing chemotherapeutic agents, which comprises a EIF4A protein having an amino acid sequence, as defined in claim | 05-07-2009 |
20090156668 | Ginkgolide Compounds, Compositions, And Extracts, And Uses Thereof - The present invention relates to Ginkgolide derivatives, compositions and extracts comprising one or more Ginkgolides and/or derivatives thereof and methods of use of the compositions to treat neurological disorders and as imaging agents. | 06-18-2009 |
20090156669 | COMBINATION OF ACTIVE INGREDIENTS WITH INSECTICIDAL AND ACARICIDAL PROPERTIES - The novel active compound combination of spiromesifen and gamma-cyhalothrin has very good insecticidal and acaricidal properties. | 06-18-2009 |
20090253784 | USE OF 3-(2,4,6-TRIMETHYLPHENYL)-4-NEOPENTYLCARBONYLOXY-5,5-TETRAMETHYLENE- - DELTA3-DIHYDROFURAN-2-ONE FOR CONTROLLING DIPTERA FROM THE CECIDOMYIIDAE FAMILY - The present application relates to the use of 3-(2,4,6-trimethylphenyl)-4-neopentylcarbonyloxy-5,5-tetramethylene-Δ | 10-08-2009 |
20090312412 | 3,4-DIAMINO-3-CYCLOBUTENE-1,2-DIONE DERIVATIVES AS POTASSIUM CHANNEL OPENERS - The present invention is directed to novel 3,4-diamino-3-cyclobutene-1,2-dione derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders related to potassium channel. | 12-17-2009 |
20090318548 | PARA-QUINOL DERIVATIVES AND METHODS OF STEREO SELECTIVELY SYNTHESIZING AND USING SAME - This application relates to para-quinol derivatives, such as analogues of manumycins, aranorosins and gymnastatins. This application also relates to methods of synthesizing and using the para-quinol derivatives. In one embodiment of the invention a compound having the chemical structure (I) is provided wherein X | 12-24-2009 |
20100010081 | ANTI-TUMOR EFFECT OF DIMERIC PHTHALIDE COMPOUND - The present invention provides for the use of a dimeric phthalide compound, the dimeric phthalide compound has broad anti-tumor activity, can directly inhibit the proliferation of tumor cells and induce cell death, but also indirectly inhibit the development of tumors by suppressing neovascularization. And further, the dimeric phthalide compound can be used alone or in combination to treat cancer, as well as in combination with chemotherapeutics to increase the efficacy of chemotherapeutics and decrease the toxicity of chemotherapeutics. | 01-14-2010 |
20100041747 | USE OF CERTAIN CHEMICAL COMPOUNDS FOR THE INHIBITION OF THE PEPTIDYL-PROLYL CIS/TRANS ISOMERASE ACTIVITY OF CYCLOPHILINS - The present invention relates to the use of certain spiro, ketone and carboxylic acid compounds for the inhibition of the peptidyl-prolyl cis/trans isomerase activity of cyclophilins and the use of these compounds for the production of a cosmetic or pharmaceutical composition for the promotion of hair growth or for the treatment or prevention of inflammatory autoimmune diseases, of diseases caused by fungi, of bacterial infections, of viral infections, of diseases caused by parasites, protozoa or worms, of cancer, of diseases of cells, of fibrosing diseases, and of non-neoplastic changes and diseases which are attributable to prions and changes in the structure and function of cellular proteins and cells. | 02-18-2010 |
20100056620 | ACTIVE COMPOUND COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERTIES - The novel active compound combinations consisting, firstly, of cyclic ketoenols and, secondly, of beneficial species (natural enemies) have very good insecticidal and/or acaricidal properties. | 03-04-2010 |
20100168226 | SPIROCYCLIC TETRONIC ACID DERIVATIVES - The present invention relates to novel spirocyclic tetronic acid derivatives of the formula (I) | 07-01-2010 |
20100173987 | ACTIVE AGENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERTIES - The novel active compound combinations consisting, firstly, of cyclic ketoenols and, secondly, of beneficial species (natural enemies) have very good insecticidal and/or acaricidal properties. | 07-08-2010 |
20110021624 | Alpha-Amino-N-Substituted Amides, Pharmaceutical Composition Containing Them and Uses Thereof - Disclosed are a series of α-amino-N-substituted amide compounds having a structure of the following formula, the pharmaceutically acceptable salts thereof, and the pharmaceutical composition comprising the same. The α-amino-N-substituted amide compounds or the pharmaceutically acceptable salts thereof according to the present invention have anti-tumor and/or anti-cancer activities in vivo and in vitro, can effectively depress the growth of various tumor cells and/or cancer cells, and thus can be used in preparing drugs for treating tumors and/or cancers. | 01-27-2011 |
20110021625 | NEURONAL CELL DEATH INHIBITOR - There is provided a neuronal cell death inhibitor having a high efficacy. A neuronal cell death inhibitor comprising a compound of general formula (1) below: | 01-27-2011 |
20110071220 | Use of Tetronic Acid Derivatives for Fighting Insects and Red Spider Mites by Watering on the Ground, Droplet Application or Immersion Application - Compounds of the formula (II) | 03-24-2011 |
20110178170 | GRISEOFULVIN ANALOGUES FOR THE TREATMENT OF CANCER BY INHIBITION OF CENTROSOMAL CLUSTERING - The present invention relates to uses of compounds having a structure as shown by formula (I) for the manufacture of a pharmaceutical composition for the treatment of cancer. Moreover, the present invention encompasses methods of treatment for said diseases. | 07-21-2011 |
20110275708 | POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO - The invention relates to a novel compound of formula I or pharmaceutically acceptable salts thereof as well as pharmaceutical, nutraceutical, and botanical drug compositions and therapeutic methods related thereto. In certain embodiments, the compounds are used for the treatment of abnormal cell growth, hyperproliferative disorders, and inflammatory diseases in mammals. In other embodiments, the invention encompasses methods to isolate and synthesize the compounds. | 11-10-2011 |
20110275709 | TELLURIUM-CONTAINING COMPOUNDS FOR AFFECTING MALE'S FERTILITY FOLLOWING CHEMOTHERAPY AND/OR RADIOTHERAPY - Use of tellurium-containing compounds for maintaining and/or augmenting fertility in a male subject following chemotherapy and/or radiotherapy is disclosed. The tellurium-containing compound is utilized in combination with a chemotherapeutic agent and/or radiation, such that the male subject treated by the chemotherapeutic agent and/or radiation and by the tellurium-containing compound is instructed to refrain from conceptive sex for a pre-determined time period, following the chemotherapy and/or radiotherapy, during which conception is undesired. | 11-10-2011 |
20110301233 | Novel Polyisoprenylated Benzophenone Derivatives from Garcinia paucinervis - Novel polyisoprenylated benzophenone derivatives isolated from the plant | 12-08-2011 |
20110306662 | Steroid-Derived Cyclopamine Analogs and Methods for Using the Same in the Prevention or Treatment of Cancer - The present invention relates to steroid-derived cyclopamine analogs and methods for using the same for inhibiting sonic hedgehog signaling and preventing or treating cancer. A method for synthesizing the analogs of the present invention from a steroid is also provided. | 12-15-2011 |
20120010281 | ANTIMICROBIAL AND ANTITUBERCULAR COMPOUNDS - Infections caused by | 01-12-2012 |
20120329865 | MOLECULES RELATED hERG ION CHANNELS AND THE USE THEREOF - Disclosed are compounds having structural formula (I, II) or a pharmaceutically acceptable sale, solvate, clathrate, or prodrug thereof, wherein R | 12-27-2012 |
20130338222 | METHODS FOR CONTROLLING VARRO MITES - The present invention relates to methods and compositions comprising spirodiclofen and/or spiromesifen for the control of bee mites and for the reduction of bee mite infestations, such as the control and reduction of infestations of parasitic bee mites, such as | 12-19-2013 |
20140128458 | POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO - The invention relates to a novel compound of the formula | 05-08-2014 |
20140171498 | C-9 OXYGEN FUNCTIONALIZED LABDANE DERIVATES - This invention relates to diterpenes of general formula (1) belonging to labdane class, isolated from | 06-19-2014 |
20140221473 | Compositions, Methods of Use, and Methods of Treatment - Embodiments of the present disclosure provide compositions including ketamine analogues, salts, and disalts, pharmaceutical compositions including ketamine analogues, salts, or disalts, methods of treatment of a condition or disease, methods of treatment using compositions or pharmaceutical compositions, and the like. | 08-07-2014 |
20150073045 | POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO - The invention relates to a novel compound of the formula | 03-12-2015 |
20160002193 | ANTICANCER COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF - The invention disclosed herein relates to novel Peribysin E analogues of general formula-I. Further the invention provides simple, economical and short synthesis of Peribysin E and its analogues of Formula I, in good yield and purity leading to the identification of more potent cell adhesion inhibitors. | 01-07-2016 |