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1,2,4-triazoles (including hydrogenated)

Subclass of:

514 - Drug, bio-affecting and body treating compositions

514001000 - DESIGNATED ORGANIC ACTIVE INGREDIENT CONTAINING (DOAI)

514183000 - Heterocyclic carbon compounds containing a hetero ring having chalcogen (i.e., O,S,Se or Te) or nitrogen as the only ring hetero atoms DOAI

514359000 - Five-membered hetero ring containing at least one nitrogen ring atom (e.g., 1,2,3-triazoles, etc.)

Patent class list (only not empty are listed)

Deeper subclasses:

Class / Patent application numberDescriptionNumber of patent applications / Date published
514384000 Chalcogen bonded directly to the triazole ring 38
Entries
DocumentTitleDate
20110190362ANTIMICROBIAL COMPOSITION USEFUL FOR PRESERVING WOOD - Antimicrobial compositions useful for preserving wood, and comprising a variety of antimicrobial compounds.08-04-2011
20100004303TREATMENT OF ENDOCRINE DYSFUNCTION USING IRON CHELATORS - The invention relates to the use of an iron chelator for the treatment or prevention of pathologies due to iron loading, e.g. related to a dysfunction, in particular a reduction or inhibition, of the secretory function of cells from endocrine glands, in the human or animal body.01-07-2010
20080312302Desferasirox Dispersible Tablets - The invention pertains to dispersible tablets comprising as active ingredient 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid or pharmaceutically acceptable salt thereof in an amount of from 5 to 40% in weight by weight of the total tablet.12-18-2008
20090124678Combined Use of Metconazole and Epoxiconazole for Reducing or Preventing the Contamination of Cereals With Mycotoxins - The invention relates to the combined use of metconazole and epoxiconazole for reducing or preventing the contamination of cereals with mycotoxins formed by mould fungus producing trichothecene.05-14-2009
20130046002TRIAZOLE COMPOUND HAVING PESTICIDAL ACTIVITIES - To provide a triazole compound which has remarkably excellent pesticidal activities. Optically active (+)-1-[2-fluoro-4-methyl-5-(2,2,2-trifluoroethylsulfinyl)phenyl]-5-amino-3-(trifluoromethyl)-1H-1,2,4-triazole represented by the following formula (I), which is obtainable by subjecting a racemic modification of 1-[2-fluoro-4-methyl-5-(2,2,2-trifluoroethylsulfinyl)phenyl]-5-amino-3-(trifluoromethyl)-1H-1,2,4-triazole to optical resolution:02-21-2013
20090306160METHODS FOR IMPROVING DRUG DISPOSITION - The invention provides a method for improving the bioavailability, preferably, oral bioavailability and/or drug disposition, e.g. brain penetration, of an iron chelator, which method comprises co-administering to a mammal, especially a human, in need of such treatment, a combination of an iron chelator and an efflux protein inhibitor.12-10-2009
20110046193DEFERACIROX DISPERSIBLE TABLETS - The invention pertains to dispersible tablets comprising as active ingredient 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid or pharmaceutically acceptable salt thereof in an amount of from 5 to 40% in weight by weight of the total tablet.02-24-2011
20130165491THERAPEUTIC AGENT FOR PAIN06-27-2013
20080293794DIARYLTRIAZOLMETHYLAMINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF - The invention concerns compounds of formula (I):11-27-2008
20080293793Fungicidal Mixtures for Wood Preservation - Using synergistically effective mixtures comprising triadimefon and/or triadimenol and at least one further known fungicidally active compound, it is possible to protect industrial materials, in particular wood, against attack, damage and/or destruction by biological pests, in particular by wood-destroying fungi.11-27-2008
20080293792Tocopherol derivatives and uses thereof - Tocopherol derivatives having the general formula:11-27-2008
20130012555Compounds, Compositions and Methods for the Treatment of Islet Amyloid Polypeptide (IAPP) Accumulation in Diabetes - Dihydroxyaryl compounds and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of IAPP or amylin fibril diseases, and the manufacture of medicaments for such treatment.01-10-2013
20110294861METHOD OF TREATMENT OF HEREDITARY HEMOCHROMATOSIS - The present invention relates to the use of Compound I of the following formula12-01-2011
20100173963COMPOUND - There is provided a compound of Formula I07-08-2010
20090170918Solid Formulation of Fungicidal Mixtures - The invention provides highly concentrated WG formulations of fungicidal mixtures, comprising 07-02-2009
20090186928Novel crystalline forms of an inhibitor of 11-beta-hydroxysteroid dehydrogenase type 1 - Novel crystalline salts of 3-[1-(4-chlorophenyl)-trans-3-fluorocyclobutyl]-4,5-dicyclopropyl-r-4H-1,2,4-triazole are potent inhibitors of 11β-hydroxysteroid dehydrogenase Type 1 and are useful for the treatment of conditions associated with Metabolic Syndrome as well as cognitive impairment. The invention also relates to pharmaceutical compositions containing these novel salts, processes to prepare these salts and their pharmaceutical compositions as well as uses thereof for the treatment of Type 2 diabetes, hyperglycemia, obesity, dyslipidemia, hypertension, and cognitive impairment.07-23-2009
20090247597AGROCHEMICAL FORMULATIONS THAT CAN BE DISPERSED IN WATER CONTAINING POLYALKOXYTRIGLYCERIDED AS PENETRATION ENHANCES - The present invention relates to novel water-dispersible agrochemical formulations such as, for example, water-based suspension concentrates and water-dispersible granules of agrochemically active compounds comprising a penetrant from the class of the polyalkoxytriglycerides, to a process for preparing these formulations and to their use for applying the active compounds comprised therein.10-01-2009
20090270471METHOD FOR INHIBITING MYCOTOXIN PRODUCTION - The present invention provides a method for prominently inhibiting the production in fungi of mycotoxin, which has serious effects on health of humans and other animals, and provides a mycotoxin production inhibitor. Mycotoxin content such as deoxinivalenol (DON) in harvested crops can be reduced without a correlation with the control effects against fungi by spraying a fungicide containing a benzimidazole-type fungicidal compound such as thiophanate-methyl as an active ingredient onto food crops such as wheat, barley, and the like. Concomitant use of the benzimidazole-type fungicidal compound and a sterol biosynthesis inhibitor (SBI agent) such as tebuconazole can further enhance the effect.10-29-2009
20100331381Substituted Phenylureas and Phenylamides as Vanilloid Receptor Ligands - The invention relates to substituted phenylureas and phenylamides, to processes for the preparation thereof, to pharmaceutical compositions containing these compounds and also to the use of these compounds for preparing pharmaceutical compositions.12-30-2010
20110071201PHENOL-CONTAINING AZOLE COMPOSITIONS FOR THE PROTECTION OF INDUSTRIAL MATERIALS - Composition, comprising 03-24-2011
20100184816Method for Reducing the Phytotoxicity of Azoles on Dicotyledonous Plants by Adding Additives - The present invention relates to a method for reducing the phytotoxicity of azoles on dicotyledonous plants by addition of additives. Furthermore, the application relates to novel compositions comprising certain triazole fungicides in combination with additives, in particular alkali metal sulphosuccinates, and their use for controlling unwanted phytopathogenic fungi.07-22-2010
20100113543Crystalline Complexes of Agriculturally Active Organic Compounds - The present invention relates to crystalline complexes comprising at least one agriculturally active organic compound A having at least one functional moiety which is capable as serving as a hydrogen acceptor in a hydrogen bond and thiophanate-methyl.05-06-2010
20100113542TRIAZOLE DERIVATIVE AS AN HSP 90 INHIBITOR - 5-[4-(2-Methylphenyl)-3-hydroxy-4H-1,2,4-triazol-5-yl]-2,4-dihydroxy-N-methyl-N-butylbenzamide is an HSP90 inhibitor and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 plays a role.05-06-2010
20110021586PHENYL-SULFAMATES AS AROMATASE INHIBITORS - There is provided a compound of Formula I01-27-2011
20120035230Compounds, Compositions, and Methods for the Treatment of Beta-Amyloid Diseases and Synucleinopathies - Dihydroxyaryl compounds and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment.02-09-2012
20090111863Compounds, Compositions and Methods for the Treatment of Beta-Amyloid Diseases and Synucleinopathies - Dihydroxyaryl compounds and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of β-amyloid diseases, such as observed in Alzheimer's disease, and synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment.04-30-2009
20100120879INSECTICIDES AS SAFENER FOR FUNGICIDES WITH PHYTOTOXIC ACTION - The present invention relates to the use of insecticides which are selected among GABA antagonists and nicotin receptor agonists/antagonists, if appropriate in combination with at least one gibberellin, as safener for fungicides which have a phytotoxic effect. Moreover, the invention relates to a method of reducing or preventing the phytotoxic effect of fungicides on plants treated therewith or on plants whose seeds or growth substrate have been or are treated with these fungicides. The invention finally also relates to compositions which comprise at least one GABA antagonist, at least one azole fungicide or strobilurin fungicide and, if appropriate, at least one gibberellin, and to compositions which comprise at least one nicotin receptor agonist/antagonist, at least one azole fungicide or strobilurin fungicide and, if appropriate, at least one gibberellin.05-13-2010
20120071530AGROCHEMICAL COMPOSITION AND METHOD FOR PREPARING AND USING THE SAME - An agrochemical composition comprises an azole active ingredient and an N,N-dialkyl long chain alkylamide. The N,N-dialkyl long chain alkylamide is present in sufficient amount to prevent or inhibit the crystallization of the azole derivative during the application of the composition to a locus. Preferred N,N-Dialkyl long chain alkylamide(s) comprised in the composition is/are selected from the group consisting of compounds of the formula (I): in which (a) R03-22-2012
20090291994Use of Pyraclostrobin as Safener for Triticonazole for Controlling Harmful Fungi - (1) Use of pyraclostrobin of the formula I11-26-2009
20100099724Formulations Comprising Triazoles and Alkoxylated Amines - The present invention relates to the use of alkoxylated amines to enhance the activity of fungicidal formulations comprising fungicidal triazoles. It also relates to formulations comprising one or more fungicidal triazoles and alkoxylated amines. These formulations are useful for the protection of any living or non-living material, such as crops, plants, fruits, seeds, objects made of wood, thatch or the like, biodegradable material and textiles against deterioration due to the action of fungi.04-22-2010
20080200528Derivatives of a 1-Phenyltriazole - Compounds of formula (I)08-21-2008
20090062357DEUTERIUM-ENRICHED FLUCONAZOLE - The present application describes deuterium-enriched fluconazole, pharmaceutically acceptable salt forms thereof, and methods of treating using the same.03-05-2009
20090137649Concentrated liquid triazole-fungicide formulations - Concentrated liquid formulations of triazole fungicides are provided and the use of such formulations in diluted form for the control of harmful fungi. The formulations are both storage stable and prevent crystallization of the triazole fungicide when applied in diluted form.05-28-2009
20090082413DEUTERIUM-ENRICHED LETROZOLE - The present application describes deuterium-enriched letrozole, pharmaceutically acceptable salt forms thereof, and methods of treating using the same.03-26-2009
20080262061COMPOSITION AND USE OF A LIQUID FUNGICIDAL FORMULATION OF MYCLOBUTANIL OR TEBUCONAZOLE FUNGICIDE - A fungicide composition containing a fungicide compound and a surfactant, wherein the fungicide is fully dissolved in the surfactant, and wherein the fungicide is selected from either myclobutanil or tebuconazole or a mixture thereof.10-23-2008
20080262060Crystalline forms of Deferasirox - The present invention provides novel crystalline forms of deferasirox, methods for their production, and methods for conversion of the novel forms to the known crystalline form I.10-23-2008
20120196909DEFERACIROX DISPERSIBLE TABLETS - The invention pertains to dispersible tablets comprising as active ingredient 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid or pharmaceutically acceptable salt thereof in an amount of from 5 to 40% in weight by weight of the total tablet.08-02-2012
20100179204CO-CRYSTALS OF PROPICONAZOLE - The present invention relates to co-crystals of propiconazole and a co-crystal forming compound.07-15-2010
20100184815AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA - Disclosed are compounds of the formula:07-22-2010
20100222400F1F0-ATPase Inhibitors and Related Methods - The present invention relates to a family of guanidine-based F1F0-ATPase inhibitors, e.g., mitochondrial F1F0-ATPase inhibitors, methods for their discovery, and their use as therapeutic agents for treating certain disorders.09-02-2010
20100144812Heterocyclic Sulfonamide Inhibitors of Beta Amyloid Production Containing an Azole - Compounds useful for lowering beta amyloid levels are provided. The compounds have the structure of formula Ia:06-10-2010
20100120878FORMULATION - This invention relates to mixtures of triazole compounds and in particular to the use of such mixtures in non-crystallising compositions. It relates to mixtures that are concentrated solutions and also to the use of the concentrated solutions in water diluted form. Furthermore, it relates to the use of such mixtures for agricultural or materials protection purposes and to the use of one triazole compound to prevent or delay crystallisation of a second triazole compound.05-13-2010
20090111862Compound - There is provided a compound of Formula I04-30-2009
20130137738FUNGICIDAL COMPOSITIONS FOR TURF TREATMENT AND IMPROVEMENT - The present invention relates to novel compositions comprising: a fungicide that inhibits mitochondrial respiration at the QoI site (QoI inhibitor), a contact fungicide, a demethylation inhibitor, and pigments, which are highly suitable for controlling unwanted phytopathogenic fungi. Moreover, the fungicidal compositions are able to control mold and fungus infection in grasses and in particular turf grasses.05-30-2013
20090036507BIS (CYANOPHENYL) METHYL-TRIAZOLE FOR USE IN PREVENTION OF BREAST CANCER - The present invention relates to the use of a lower dosage of bis(cyanophenyl)methyl-triazole of the formula (I) or a pharmaceutically acceptable salts thereof, for the preparation of a pharmaceutical composition for the prevention of conditions responsive to aromatase inhibition and to inhibition of estrogen biosynthesis, especially breast cancer, in mammals.02-05-2009
20100331380Compounds, Compositions, and Methods for the Treatment of Beta-Amyloid Diseases and Synucleinopathies - Dihydroxyaryl compounds and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of β-amyloid diseases, such as observed in Alzheimer's disease, and synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment.12-30-2010
20110245306CO-CRYSTALS - The present invention relates to co-crystals of propiconazole and a co-crystal forming compound.10-06-2011
20110039904Alcohol alkoxylates, agents comprising the same and use of the alcohol alkoxylates as adjuvants in the agrochemical field - The present invention relates to certain alcohol alkoxylates of the amphiphilic type, to agrochemical agents comprising them, and to the use of the alcohol alkoxylates as activity-improving adjuvants in the agrochemical field and particularly in the field of plant protection. The alcohol alkoxylates are alkoxylated alcohols of the formula (I)02-17-2011
20110144171THIOPENE CONTAINING ANALOGUES OF FLUCONAZOLE AS ANTIFUNGAL AGENTS AND PROCESS FOR THEIR PREPARATION - The present invention discloses novel compounds of the Formula (1), containing thiophene moieties and pharmaceutically acceptable salts thereof, methods for preparing these compounds, the use of these compounds in prevention and treatment of fungal infections, and pharmaceutical preparations containing these novel compounds.06-16-2011
20110257234Agrochemical Auxiliary Compositions - Suggested are agrochemical auxiliary compositions, comprising (a) alkoxylated polyol esters, (b) optionally alkoxylated alk(en)yl oligoglycosides, and (c) fatty acids or their salts.10-20-2011
20080249150HETEROCYCLIC SULFONAMIDE INHIBITORS OF BETA AMYLOID PRODUCTION CONTAINING AN AZOLE - Compounds useful for lowering beta amyloid levels are provided. The compounds have the structure of formula Ia:10-09-2008
20090030054CYTOPLASMIC ANTIGENS FOR DETECTION OF CANDIDA - The present invention relates to a method and a means of diagnosing 01-29-2009
200803190371,2,4-TRIAZOL-1-YL BISPHENYL DERIVATIVES FOR USE IN THE TREATMENT OF ENDOCRINE-DEPENDENT TUMORS - There is provided a compound of Formula I12-25-2008
20080275097Non-nucleoside reverse transcriptase inhibitors - Compounds of Formula I:11-06-2008
20100152261NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND - A nitrogen-containing heterocyclic derivative represented by the following general formula (I), or a hydrate or solvate thereof, which has a selective antagonistic action on the muscarinic M06-17-2010
20080255216Diaryltriazoles as Inhibitors of 11-Beta-Hydroxysteroid Dehydrogenase-1 - 2,5-Diaryl-1,2,4-triazole derivatives of structural formula I are selective inhibitors of the 11&bgr;-hydroxysteroid dehydrogenase Type 1 enzyme (11&bgr;-HSD-1). The compounds are useful for the treatment of diabetes, hyperglycemia, obesity, insulin resistance, atherosclerosis, dyslipidemia, hyperlipidemia, hypertension, and Metabolic Syndrome. Also disclosed are novel compounds of structural formula II which are inhibitors of 11&bgr;-HSD-1.10-16-2008
20110053996Use of phenyltriazoles for controlling insects and spider mites by watering, droplet application or dip application or by treating seed - The present invention relates to the use of compounds of the formula (I)03-03-2011
20080287512Plant Protection Composition Including an Active Compound Selected from Azoles and a Solvent, and Useful Solvent Composition - The present invention relates to a concentrated plant protection composition containing an active compound selected from azoles and preferable triazoles such as tebuconazole. The composition contains at least one solvent. The composition is stable and easy for farmers to use. The present invention further relates to a useful solvent composition particularly suitable for implementing the plant protection composition.11-20-2008
20090163564Translational Dysfunction Based Therapeutics - Provided are methods and compositions for inhibiting eukaryotic translation initiation factor eIF4E. Such methods and compositions may be used alone or in conjunction with other therapies, such as gene therapies, for inhibiting cell proliferation and/or treating cancer.06-25-2009
20110105575METHOD OF TREATMENT OF HEREDITARY HEMOCHROMATOSIS - The present invention relates to the use of Compound I of the following formula05-05-2011
20100298394ANTIFUNGAL AGENTS AS NEUROPROTECTANTS - Provided herein are compounds, compositions and methods for protecting neuronal and glial cells.11-25-2010
20090215845Fungicidal mixtures - Synergistically effective mixtures comprising prochloraz and tebuconazole and fungicidal compositions based thereon are highly suitable for protecting industrial materials, in particular wood and timber products, against attack, damage and/or destruction by biological pests.08-27-2009
20090048319Method of Using a Micronutrient as Safener for a Triazole for Controlling Harmful Fungi - A method of using a micronutrient selected from the group consisting of salts and adducts of Mg, Ca, B, Mn, Fe, Co and Zn and Mo as a safener for a triazole, selected from the group consisting of azaconazole, bitertanol, bromuconazole, cyproconazole, difenoconazole, diniconazole, enilconazole, epoxiconazole, fenbuconazole, fluquinconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, ipconazole, metconazole, myclobutanil, penconazole, propiconazole, prothioconazole, simeconazole, tebuconazole, tetraconazole, triadimenol, triadimefon and triticonazole or salts or adducts thereof for controlling harmful fungi.02-19-2009
20100056590POLYMORPHIC FORMS OF DEFERASIROX (ICL670A) - The invention relates to crystalline forms of -[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid and to its amorphous form, to processes for the preparation thereof, to compositions containing the same and their uses for the manufacture of a medicament for the treatment of the human body.03-04-2010
20110092556PLANT DISEASE CONTROLLING COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE - There is provided a plant disease controlling composition comprising at least one compound (A) selected from the group consisting of metconazole, bromuconazole and epoxyconazole, as well as a compound represented by the formula (I): as active ingredients. Also provided is a method for controlling a plant disease, which comprises applying at least one compound (A) selected from the group consisting of metconazole, bromuconazole and epoxyconazole, as well as the compound represented by the formula (I) to a plant, a seed of a plant or a cropland.04-21-2011
20090030053FUNGICIDAL COMPOSITIONS - The invention relates to a composition capable of controlling phytopathogenic fungi on a plant or propagation material thereof said composition comprising as active ingredients a mixture of: (A) Difenoconazole or a salt or metal complex thereof; and (B) Chlorothalonil, wherein said Difenoconazole or the salt or metal complex thereof and said Chlorothalonil are present in said composition in amounts which produce a synergistic effect. The composition of the invention is also suitable for the protection of industrial materials.01-29-2009
20090197929Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi and Agents Containing Said Compounds - The present invention relates to azolylmethyloxiranes of the general formula I08-06-2009
20120010259Methods of Treating an Overweight or Obese Subject - The invention herein generally relates to methods of treating a subject having an overweight or obese condition, and overweight- or obesity-related conditions. In one embodiment, the invention herein provides a method of treating a subject having an overweight or obese condition involving administering to the subject in need thereof, an amount of a pharmaceutical composition including a MetAP-2 inhibitory compound, or a salt, ester, or prodrug thereof, effective to result in weight loss in the subject.01-12-2012
20120015993Novel Pharmaceutical Forms, and Methods of Making and Using the Same - Crystalline salts, polymorphs, solvates, and hydrates of bicalutamide, 5-fluorouracil, donepezil, anastrozole, nelfinavir, mirtazapine, lansoprazole, and tamsulosin, or derivatives thereof are provided by the subject invention. Methods of making and using the same are also provided.01-19-2012
20120309801CALIXARENE-BASED PEPTIDE CONFORMATION MIMETICS, METHODS OF USE, AND METHODS OF MAKING - A class of topomimetic calixarene-based peptide mimetics is described. Calixarene-based peptide mimetics have various biological activities such as, for example, bactericidal activity, antiangiogenic activity, and/or antitumor activity. Methods of use and methods of designing calixarene-based peptide mimetics are described.12-06-2012
20100197749CHEMICAL COMPOUNDS - The invention relates to chemical compounds of formula (I) and (II):08-05-2010
20110065766METHODS OF USE OF ANTIVIRAL COMPOUNDS - The present invention relates, in part, to methods of treatment, prevention, and inhibition of viral disorders. In one aspect, the present invention relates to inhibition of the M2 proton channel of influenza viruses (e.g. influenza A virus) and other similar viroporins (e.g., VP24 of Ebola and Marburg viruses; and NS3 protein of Bluetongue). The present invention further relates, inter alia, to compounds which have been shown to possess antiviral activity, in particular, inhibiting the M2 proton channel of influenza viruses.03-17-2011
20110105576PESTICIDAL COMBINATIONS - A method of controlling or preventing pathogenic damage and/or pest damage in a plant propagation material, a plant, part of a plant and/or plant organ that grow at a later point in time, which comprises applying on the plant, part of the plant, plant organ, plant propagation material or a surrounding area thereof a combination comprising (I) prochloraz, (II) metconazole, and optionally (III) metalaxyl or mefenoxam.05-05-2011
20120165378THIOPHENE-CARBOXAMIDES USEFUL AS INHIBITORS OF PROTEIN KINASES - The present invention relates to compounds useful as inhibitors of protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, or disorders. The invention also relates to processes for preparing compounds of the inventions.06-28-2012
20120129901TRITERPENOID DERIVATIVES USEFUL AS ANTIPROLIFERATIVE AGENTS - Formula (I) and (II). The present invention relates to the use of a new lupane derivative of general formula (I) or (II), or a pharmaceutically acceptable salt, crystal form, complex, hydrate, or hydrolysable ester thereof, for preventing and/or inhibiting tumor growth and for treating cancer and other proliferative diseases, more particularly for treating leukemia, liver, cervical, colon and prostate cancer. The present invention also relates to the synthesis of these compounds and to pharmaceutical compositions which contain them.05-24-2012
20100173964PHARMACEUTICAL COMPOSITION THAT INCLUDES A DIPEPTIDYL PEPTIDASE-IV INHIBITOR - The present patent application relates to a pharmaceutical composition for oral administration that includes a certain pyrrolidine derivative as DPP-IV inhibitor, and a pharmaceutically acceptable excipient. More particularly, the present invention contemplates pharmaceutical compositions that include melogliptin and a pharmaceutically acceptable excipient as well as to processes for preparing the pharmaceutical composition and the use of the composition in reducing glucose level in a subject. The present invention also contemplates an impurity associated with melogliptin.07-08-2010
20100048655Comb Polymers and Use Thereof for the Production of Active or Effective Ingredient Formulations - The present invention relates to novel comb polymers, to a process for their manufacture and to the use thereof in the stabilization in an aqueous phase of active or effect substances which are insoluble or sparingly soluble in water. The invention furthermore relates to the use of the comb polymers in the manufacture of active substance formulations or active substance preparations of water-insoluble active or effect substances, in particular of active substances for plant protection.02-25-2010
20090082412DEUTERIUM-ENRICHED DEFERASIROX - The present application describes deuterium-enriched deferasirox, pharmaceutically acceptable salt forms thereof, and methods of treating using the same.03-26-2009
20120190716METHODS AND USES OF CYTOCHROME P450 INHIBITORS - Methods are provided for treating or preventing chronic obstructive pulmonary diseases such as emphysema, and fibrotic diseases including heart, liver, kidney and vascular diseases, by administering to a subject a pharmaceutical composition comprising a compound that inhibits cytochrome P450RA or CYP26.07-26-2012
20090082414DEUTERIUM-ENRICHED VIRAMIDINE - The present application describes deuterium-enriched viramidine, pharmaceutically acceptable salt forms thereof, and methods of treating using the same.03-26-2009
20110003872MATERIAL FORMED FROM DENDRITIC MOLECULES CONTAINING ASSOCIATIVE GROUPS - The present invention relates to a material comprising dendritic molecules each constituted of fragments that are at least bifunctional and of fragments that are at least trifunctional joined together by ester or thioester bridges, alone or in combination with amide or urea bridges, said bridges being formed from two functions carried by different fragments, said molecules containing, on the fragments located at the ends of the dendritic branches, associative end groups capable of forming associations with one another by hydrogen bonds and joined covalently to the functions that are not involved in said bridges. It also relates to the method of production thereof, as well as to its uses and to compositions, notably cosmetic, containing this material.01-06-2011
20110319457DEFERACIROX DISPERSIBLE TABLETS - The invention pertains to dispersible tablets comprising as active ingredient 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid or pharmaceutically acceptable salt thereof in an amount of from 5 to 40% in weight by weight of the total tablet.12-29-2011
20130012556Bioactive Agrichemical Compositions and Use Thereof - Bioactive agrichemical concentrates and compositions having improved bioactivity comprising combinations of acid solutions and conventional bioactive agrichemical actives or formulations.01-10-2013
20120149744ANTI-MITOTIC ANTI-PROLIFERATIVE COMPOUNDS - Substituted triazole compounds and pharmaceutical compositions thereof are presented. Also presented are methods for treating a pathology linked to a hyperproliferative disorder by administering the substituted triazole compounds to a patient in need thereof.06-14-2012
20130023571N- ( 4-PERFLUOROALKYL-PHENYL) -4-TRIAZOLYL-BENZAMIDES AS INSECTICIDES - The present invention relates to novel triazole-substituted benzamide derivatives, to processes and intermediates for preparing them, to methods of using them to control insect, acarine, nematode and mollusc pests, and to insecticidal, acaricidal, nematicidal and molluscicidal compositions comprising them. Formula (I).01-24-2013
20130172395COMPOUNDS FOR ANTI-FUNGAL TREATMENT - Provided are methods of treating or preventing a fungal infection in a subject. The methods comprise selecting a subject with or at risk of developing a fungal infection and administering to the subject a therapeutically effective amount of toremifene and fluconazole or derivatives thereof.07-04-2013
20080249149Crystalline Forms of Rizatriptan Benzoate - The present invention is directed to the novel polymorphic Form A and Form B of Rizatriptan benzoate, processes for the preparation thereof and pharmaceutical compositions comprising these crystalline forms.10-09-2008
20110237634NOVEL CRYSTALLINE FORMS OF AN INHIBITOR OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 - Novel crystalline salts of 3-[4-(3-ethanesulfonyl-propyl)-bicyclo[2.2.2]oct-1-yl]-4-methyl-5-(2-trifluoromethyl-phenyl)-4H-1,2,4-triazole are potent inhibitors of 11β-hydroxysteroid dehydrogenase Type 1 and are useful for the treatment of conditions associated with Metabolic Syndrome as well as cognitive impairment. The invention also relates to pharmaceutical compositions containing these novel salts, processes to prepare these salts and their pharmaceutical compositions as well as uses thereof for the treatment of Type 2 diabetes, hyperglycemia, obesity, dyslipidemia, hypertension, and cognitive impairment.09-29-2011
20090042963Triazole-Based Fungicidal Mixtures - Fungicidal mixtures, comprising02-12-2009
20130203826Pure Intermediate - The present invention relates to an improved process for the preparation of Letrozole (I) and its synthetic intermediate 4-[(1-(1,2,4-triazoly)methyl]benzonitrile (III). In particular, it relates to a process to prepare Letrozole and its intermediate (III) substantially free from regioisomeric impurities. The present invention further relates to acid addition salts of 4-[(1-(1,2,4-triazoly)methyl]benzonitrile (III) such as the oxalate salt, and also to Letrozole (I), the intermediate (III) and salts thereof preparable by the processes of the present invention.08-08-2013
20130210874DUAL-ACTING ANTIHYPERTENSIVE AGENTS - In one aspect, the invention relates to compounds having the formula:08-15-2013

Patent applications in class 1,2,4-triazoles (including hydrogenated)

Patent applications in all subclasses 1,2,4-triazoles (including hydrogenated)