Class / Patent application number | Description | Number of patent applications / Date published |
514195000 | 3-position substituent contains -COOC- group | 12 |
20080312203 | Bicyclic 6-Alkylidene-Penems as Beta-Lactamase Inhibitors - The present invention provides a compound of formula I | 12-18-2008 |
20090075965 | DEUTERIUM-ENRICHED AMOXICILIN - The present application describes deuterium-enriched amoxicilin, pharmaceutically acceptable salt forms thereof, and methods of treating using the same. | 03-19-2009 |
20090075966 | DEUTERIUM-ENRICHED TAZOBACTAM - The present application describes deuterium-enriched tazobactam, pharmaceutically acceptable salt forms thereof, and methods of treating using the same. | 03-19-2009 |
20100009954 | BETA-LACTAMASE INHIBITORY COMPOUNDS - Inhibitors of the enzyme beta-lactamase are provided. The compounds are adapted to inhibit beta-lactamase as produced by beta-lactam resistant bacterial strains. Methods of treatment of beta-lactam resistant bacterial infections in patients are provided. | 01-14-2010 |
20100048528 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF BETA-LACTAMASES - This invention discloses and claims methods for inhibiting bacterial β-lactamases and treating bacterial infections by inhibiting bacterial β-lactamases in man or an animal comprising administering a therapeutically effective amount to said man or said animal of a compound, or pharmaceutically acceptable salt thereof, of formula (I) either alone or in combination with a β-lactamine antibiotic wherein said combination can be administered separately, together or spaced out over time. Pharmaceutical compositions comprising a compound of formula (I), or a combination of a compound of formula (I) and a therapeutically effective amount of a β-lactamine antibiotic, and a pharmaceutically acceptable carrier are also disclosed and claimed. | 02-25-2010 |
20130023512 | Compositions for Combating Beta-Lactamase-Medicated Antibiotic Resistance Using Beta-Lactamase Inhibitors Useful For Injection - The invention describes a composition for combating beta-lactamase-mediated antibiotic resistance using beta-lactamase inhibitor useful for injection, capable of pharmaceutical application. The invention relates to pharmaceutical composition containing ceftriaxone (normally as ceftriaxone sodium) and sulbactam (normally as sulbactam sodium). Such compositions are found to be useful for intramuscular or intravenous administration as antibiotics for hospitalized patients with serious infections. Specifically, this invention relates to a pharmaceutical composition further including an aminocarboxylic acid chelating agent, for example, ethylenediaminetetraacetic acid (EDTA), or a pharmaceutically acceptable salt thereof. The pharmaceutical compositions of this invention have been found normally to enhance resistance to particulate formation in solutions to be administered parenterally. The invention also gives details of the dosage forms stored in sealed containers to be reconstituted before use. The invention also gives a process to manufacture these compositions. The invention gives a method of treating a subject having a condition or disorder, wherein a treatment with ceftriaxone sodium and sulbactam sodium is indicated. | 01-24-2013 |
20140057888 | COMPOUNDS AND THEIR USE - Described herein are compounds and their use in the treatment of infections. The compound of formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, solvates, pharmaceutically acceptable salts and pharmaceutical compositions described herein are also useful as β-lactamase inhibitors, which restore or enhance the antibiotic spectrum of a suitable antibiotic agent. The compounds of formula (I) act as inhibitors of β-lactamases. These compounds restore/potentiate the activities of β-lactam antibiotics against carbapenemases. These compounds find use in diagnostic method for detecting β-lactamases. | 02-27-2014 |
20140128358 | INSECTICIDAL PYRROLIDIN-YL-ARYL-CARBOXAMIDES - The invention relates to compounds of formula (I): where A | 05-08-2014 |
20160030398 | VETERINARY COMPOSITIONS FOR TREATING MASTITIS - The present invention relates to a veterinary composition for the prophylaxis and treatment of mastitis in mammals, preferably cows. The formulations of the present invention comprise two parts that are optionally administered to the animal as a blended formulation or two separate formulations. The first part is a seal formulation comprising a gel base and a non-toxic heavy metal salt in the base. The second part of the formulation is an oil-based product preferably containing an antibiotic in an oil-based formulation. The oil-based formulation may also optionally contain any other pharmaceutically active agent for the treatment or prophylaxis of disease in cattle. | 02-04-2016 |
20160175318 | COMPOSITIONS COMPRISING ANTIBACTERIAL AGENT AND TAZOBACTAM | 06-23-2016 |
20160176897 | 7-AMINOCEPHEM DERIVATIVE COMPOUNDS | 06-23-2016 |
20160199360 | COMPOSITIONS AND METHODS FOR TREATING BACTERIAL INFECTIONS | 07-14-2016 |