Entries |
Document | Title | Date |
20080200443 | Zinc complexes of natural amino acids for treating elevated copper caused toxicities - The present invention relates to the use of zinc complexes of natural amino acids, especially L-arginine, L-lysine, L-ornithine, and other natural amino acids, in a molar ratio of about 1:2 (metal:amino acid), and formulations thereof. These pharmaceutical compositions offer better tolerated and faster acting regimens than common zinc salts (i.e., acetate, sulfate, etc.) for long term maintenance therapy of diseases caused by abnormal elevated copper levels, such as in Wilson's disease, inflammatory and fibrotic diseases and Alzheimer's disease. | 08-21-2008 |
20080249078 | Method and use of nanoparticles to bind biocides in paints - This invention relates to the use of a combination of selected substances in paint to prevent the settlement and growth of different biofouling organisms with a reduced negative effect on the ecosystems compared to present methods. | 10-09-2008 |
20080255081 | Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin - Free radicals and reactive oxygen species have the potential to damage a wide variety of organic molecules, typically by oxidizing certain moieties. These damaging species can, for example, be produced by an organism as a by-product of cellular respiration or by the reaction of iron(II) and peroxide. The present invention includes methods of using aryl-substituted heterocyclic iron chelating compounds as antioxidants, as well as preventing the reduction of iron(III) to iron(II). In addition, the present invention provides methods of treating conditions such as inflammatory disease, neoplastic disease, and ischemic episodes. | 10-16-2008 |
20090029961 | Bio-Film Resistant Surfaces - The present invention relates to methods and compositions for rendering a surface resistant to bio-film formation by a combination of an alkanediol and an antimicrobial agent (and, optionally, an organic hydroxy acid). The invention provides for compositions which may be used to render surfaces bio-film resistant, articles having bio-film resistant surfaces, and methods for their preparation. The present invention may be advantageously applied to medical articles as well as articles used in non-medical contexts, such as child care or food preparation. | 01-29-2009 |
20090042848 | COPPER COMPLEXES - There are described mononuclear copper complexes having anti-inflammatory activity. The complexes include copper complexes of indomethacin. There are also provided methods for the prophylaxis or treatment of inflammation comprising administering such complexes to a mammalian subject. | 02-12-2009 |
20090042849 | Phosphorylation of 5-lipoxygenase at ser523 and uses thereof - The present invention provides novel mechanisms that regulate the production of anti-inflammatory and pro-inflammatory mediators generated by 5-lipoxygenase. In this regard, the present invention establishes that phosphorylation of 5-Lipoxygenase by protein kinase A, has a crucial role in determining the end products of 5-Lipoxygenase. With translocation to the nucleus, potent proinflammatory leukotrienes are produced, whereas following phosphorylation by protein kinase A, anti-inflammatory mediators are produced. The present invention also discloses compounds that regulate these pro- and anti-inflammatory mediators. | 02-12-2009 |
20090042850 | COMPOSITIONS AND METHODS FOR CYTOPROTECTION - The present invention provides compositions and methods for cytoprotection. In particular, it provides zinc chelate compositions comprising at least one zinc ion and at least one aminothiol ligand. | 02-12-2009 |
20090054391 | Biologically active complex - The invention relates to an aqueous solution containing at least one species selected from the group consisting of a 1:1 molar complex of TeO | 02-26-2009 |
20090082324 | Bifunctional Resorcinol, Thioresorcinol, and Dithioresorcinol Derivative Metal Chelating Conjugates - The present invention is directed to metal chelating conjugates for use as metallopharmaceutical diagnostic or therapeutic agents. Specifically, conjugates of the present invention include one or more carriers, a linker, and metal coordinating moiety comprising a resorcinol, thioresorcinol, or dithioresorcinol derivative through which the metal coordinating moiety is bonded to the linker. | 03-26-2009 |
20090105206 | Copper Melphalan And Copper Tegafur As Anti-Tumor Agents - The present invention relates to the use of copper compounds of general formula Cu(L) | 04-23-2009 |
20090105207 | Copper (1) Complex - Copper (I) chloride complex of pyrazinic acid is prepared, characterized by elemental analysis, IR, UV-visible spectra and its crystal structure determined by single crystal diffraction methods. This compound is found to exhibit a very positive influence as a drug, in a pharmaceutical acceptable composition for different incurable diseases, e.g. myopathy or weakness of muscles in general, infertility, and certain genetically causes disorders in mammals. These products were found to improve symptoms of myopathy, male infertility, fatigue and weakness of muscles for different reasons, and certain genetically causes disorders in mammals. It also enhanced regeneration of tissue affected by skin burns, scars, improved alopecia, decreased blood lipids and helped in loss of weight in obese patients. The observed wide scope of activities probably due to stem cell stimulation, enhancement the immune system and role of copper dependent enzyme activity. | 04-23-2009 |
20090270357 | Method and use of nanoparticles to bind biocides in paints - This invention relates to the use of a combination of selected substances in paint to prevent the settlement and growth of different biofouling organisms with a reduced negative effect on the ecosystems compared to present methods. | 10-29-2009 |
20090312301 | Transition Metal Complexes for Inhibiting Resistance in the Treatment of Cancer and Metastasis - The present invention relates to organometallic compounds useful in the treatment of metastasis. The organometallic compounds comprise a ligand that is covalently bound to a bioactive compound, which is an inhibitor of a resistance pathway or a derivative thereof. Preferably, the organometallic compounds are half-sandwich (“piano-stool”) compounds. The compounds of the present invention offer a high variability with respect to the bioactive compound and to the nature of the ligand bound to a central transition metal. | 12-17-2009 |
20100069345 | Lanthanide-porphyrin complexes as anti-tumor agents - The present invention relates to lanthanide porphyrin complexes and their uses as anti-tumor agents. The described complexes show promising cytotoxic properties toward cancer cells in both in vitro and in vivo studies. | 03-18-2010 |
20100120738 | ANTI-APOPTOTIC BENZODIAZEPINE RECEPTOR LIGAND INHIBITORS - The present invention provides low molecular weight porphyrin compositions for inhibiting, preventing or delaying the binding of a ligand of a mitochondrial benzodiazepine receptor. The invention also provides pharmaceutical compositions comprising these porphyrin compositions and their use in the treatment of conditions involving the mitochondrial benzodiazepine receptor or interactions between the receptor and the mitochondrial permeability transition pore e.g., drug overdose or apoptosis including neural degeneration and radiation-induced apoptosis. | 05-13-2010 |
20100152153 | Nitric Oxide Releasing Compounds - Compositions comprising nitrosyl-cobinamide are provided. Also provided are methods for treating hypertension, which comprise administering therapeutically effective amounts of nitrosyl-cobinamide. Also provided are methods for producing nitrosyl-cobinamide. | 06-17-2010 |
20100152154 | NOVEL PLATINUM COMPOUNDS FOR TREATING CANCER - A series of platinum compounds and methods of treating cancer by said platinum compounds are disclosed. | 06-17-2010 |
20100305083 | SUBSTITUTED PORPHYRINS - To improve bioavailability of the catalytic metalloporphyrin-based SOD mimics Mn(III) 5,10,15,20-tetrakis[N-ethylpyridinium-2-yl]porphyrin (MnTE-2-PyP | 12-02-2010 |
20100324008 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING - Described herein are prostate specific membrane antigen (PSMA) binding conjugates that are useful for delivering therapeutic, diagnostic and imaging agents. Also described herein are pharmaceutical composition containing them and methods of using the conjugates and compositions. Also described are processes for manufacture of the conjugates and the compositions containing them. | 12-23-2010 |
20110021483 | Platinum (IV) Complexes - Provided are nitroplatinum(IV) complexes containing a bidentate dicarboxylate ligand (e.g., oxalate) which maybe useful treating various forms of proliferative diseases, such as cancer. In some instances the platinum(IV) complexes are relatively stable and may be suitable for oral administration. Also provided are methods of treatment, as well as kits and unit dosages. | 01-27-2011 |
20110021484 | Gallium compounds and methods of use to treat inflammatory bowel disease - Provided are formulations and methods for treating inflammatory bowel disease, including Crohn's disease, ulcerative colitis, and Johne's disease. The formulations provided comprise pharmaceutically acceptable gallium compounds; the methods provided comprise means of using such formulations in the treatment of inflammatory bowel disease and closely related disorders. | 01-27-2011 |
20110039815 | MACROCYCLIC METAL COMPLEXES FOR THEIR USE AS ANTICANCER AGENTS - In one embodiment the present invention relates to a method of treating cancerous cells in a mammal comprising the steps of administering to the cancerous cells an effective amount of a cyclic amine wherein the cyclic amine contains sulfur or nitrogen and the structure includes an interchealted metal ion. | 02-17-2011 |
20110077230 | COPPER ORGANOCOMPLEXES, USE THEREOF AS ANTITUMOR MEANS AND FOR PROTECTING HEALTHY TISSUE FROM IONIZING RADIATION - The present invention relates to copper-organic complexes and pharmaceutical compositions containing the same. They can be used especially in the treatment of diseases caused by hyperproliferative cells and, in addition, protect healthy tissue from ionizing radiation. They are prepared by reacting a copper(II) acylate with an organic compound selected from 4-[bis(2-chloroethyl)amino]-D,L-phenyl-alanine (sarcolysine), the hydrochloride thereof, N-(2-furanidil)-5-fluorouracil (tegafur) and aminocarbonylaziridine (leacadin) at acidic to neutral pH in a chloroform/methanol mixture. | 03-31-2011 |
20110183951 | Copper (1) Complex - A Copper (I) chloride complex of pyrazinic acid having the empirical formula C | 07-28-2011 |
20110212936 | HIGH-VALENT PALLADIUM FLUORIDE COMPLEXES AND USES THEREOF - The present invention provides novel high-valent palladium fluoride complexes. The complexes typically include multi-dentate ligands that stabilize the octahedral coordination sphere of the palladium(IV) atom. These complexes are useful in fluorinating organic compounds, in particular aryl-containing compounds. The invention is particularly useful for fluorinating compounds with | 09-01-2011 |
20110245218 | Use of Maleimide Salts to Control Phytopathogenic Fungi - The present invention relates to the use of new and known maleimide salts for controlling phytopathogenic fungi, and also to methods for controlling phytopathogenic fungi in crop protection, in the household and hygiene sectors and in materials protection, and also to crop protection compositions comprising these maleimide salts. | 10-06-2011 |
20110245219 | VIRUCIDAL DISINFECTANT - A virucidal alcohol-based disinfectant, in particular for sanitary and/or surgical disinfection of hands, wherein at least one acid compound is present, is distinguished in that urea is present. | 10-06-2011 |
20110269730 | Metal Complexes of Thiourea and Derivatives as Metal Delivering Anti-Cancer and Anti-Inflammatory Agents - The present invention relates to metal thiourea complexes comprising N-substituted thiourea ligands and sulfur-coordinated metal ions, and methods for using the metal thiourea complexes for delivering otherwise unstable or impermeable metal ions to mammalian cells, for inhibiting cancer cell growth and inflammation, and for inhibiting the activities of associated drug targets under in vitro and in vivo conditions. The metal complexes of N-substituted thiourea are defined by the following formula (Ia or Ib) wherein R | 11-03-2011 |
20120178729 | CRYSTALLINE FORM I ROSUVASTATIN ZINC SALT - The present invention relates to crystalline Form I rosuvastatin zinc (2:1) salt, method of preparation thereof and use thereof as pharmaceutically active ingredient for the treatment of diseases related to lipid metabolism including hyperlipoproteinemia, hypercholesteremia, dyslipidemia and atherosclerosis. | 07-12-2012 |
20120270850 | METAL DELIVERY AGENTS AND THERAPEUTIC USES OF THE SAME - The present invention relates to metal complexes, processes for their preparation and their use as pharmaceutical or veterinary agents, in particular for the treatment of conditions in which metal delivery can prevent, alleviate or ameliorate the condition. There are a number of clinical conditions which are caused by or associated with abnormal levels of metals (typically low metal levels). Conditions in of this type include cancer and conditions characterised by or associated with oxidative damage, more specifically neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease or Huntington's disease. The invention also relates to ligands useful in the preparation of metal complexes of this type. | 10-25-2012 |
20130035322 | GOLD COMPLEXES - Gold (I) hydroxide complexes of the form Z-Au-OH and digold complexes of the form Z—Au-(μOH)—Au—Z where groups Z are two electron donors are provided. The groups Z may be carbenes, for example nitrogen containing heterocyclic carbenes (NHCs), phosphines or phosphites. The complexes can be used as catalysts, for example in reactions such as hydration of nitriles, skeletal arrangement of enynes, alkoxycyclisation of enynes, alkyne hydration, the Meyer-Shuster reaction, 3,3′ rearrangement of allylic acetates, cyclisation of propargylic acetates, Beckman rearrangements and hydroamination. The complexes can be used in medicine, for example in the treatment of cancer. | 02-07-2013 |
20130116224 | Method and Composition for Treatment of Tumors - A method for ameliorating tumors which result from high or increased activity of Gli by treating a human subject evidencing tumor growth by treating the subject with a deactivating effective amount of CTC-96 to reduce or inhibit tumor growth. | 05-09-2013 |
20130123227 | NOVEL ORGANO-PALLADIUM COMPLEXES - The present invention relates generally to novel complexes of palladium or a palladium salt, lipoic acid and a long chain fatty acid, where the palladium is bonded to lipoic acid via both sulfurs and carboxyl group oxygens of lipoic acid, and where the long chain fatty acid is bonded to the palladium via the carboxyl group of the long chain fatty acid. The complexes are useful as cancer chemotherapy agents. | 05-16-2013 |
20130137669 | MACROCYCLIC LACTONE RESISTANCE MARKER FOR DIROFILARIA IMMITIS - The invention relates to a method for determining the responsiveness of a | 05-30-2013 |
20130190284 | X-Ray and Gamma-Photon Activable Organic Compounds, Their Preparation and Their Uses - The present invention relates to a X-ray and gamma-photon activable compound responding to the following formula (I). The present invention also relates to methods of synthesizing a compound according to the invention, and to an aqueous or physiological solution comprising at least one compound of the invention. The present invention also concerns a method of liberating a biologically active compound, said method involving the step of irradiating at least one compound, or at least one aqueous or physiological solution according to the invention. Finally, the present invention relates to a pharmaceutical composition comprising at least one compound, or at least one aqueous or physiological solution according to the invention. | 07-25-2013 |
20130237509 | STRONTIUM (M) ASCORBATE, COMPOSITIONS CONTAINING SAME, MEHTOD FOR MAKING SAME AND METHOD OF USING SAME - A compound of formula (ascorbate) | 09-12-2013 |
20130237510 | METHOD OF TREATING NEUROENDOCRINE TUMORS - Methods and compositions for treating neuroendocrine tumors are disclosed. | 09-12-2013 |
20130267490 | TOPICAL PHARMACEUTICAL COMPOSITION COMPRISING NANONIZED SILVER SULFADIAZINE AND CHLORHEXIDINE GLUCONATE - The invention relates to an improved topical pharmaceutical composition for burn treatment and microbial infections on human beings or animals. The pharmaceutical composition comprises 0.1% w/w to 1% w/w of an antimicrobial drug, i.e., silver sulfadiazine and 0.2% w/w antiseptic, i.e., chlorhexidine gluconate; wherein silver sulfadiazine is in nanonized form. | 10-10-2013 |
20130274237 | COMPOSITION INCLUDING CHLOROPHYLL A AS AN ACTIVE INGREDIENT FOR PREVENTING AND TREATING TH2-MEDIATED IMMUNOLOGICAL DISEASES - The present invention relates to a composition including chlorophyll a as an active ingredient for preventing and treating Th2-mediated immunological diseases. The composition of the present invention is very effective for preventing and treating atopic dermatitis which is one of the Th2-mediated immunological diseases. Chlorophyll a is a natural ingredient used to treat atopic dermatitis and is advantageous in that it causes absolutely no side effects in humans. Further, the composition of the present invention may be applied as a medical composition including chlorophyll a, which has preventive and therapeutic effects for atopic dermatitis, as a food composition, as a cosmetic composition, and for various other products using chlorophyll a, and has excellent marketability. | 10-17-2013 |
20130316997 | ANTIBACTERIAL RESIN COMPOSITION - An antibacterial resin composition comprising a thermoplastic resin or a thermosetting resin that contains a metal compound represented by the following formula (1), permitting the metal such as silver having antibacterial power to efficiently elute out and the eluted metal to remain stable as metal ions so that excellent antibacterial power can be exhibited using only a decreased amount of an expensive compound containing silver or the like, | 11-28-2013 |
20140018340 | Insulin Mimetic Active Comprising Oxodiperoxo Vanadates and a Pharmaceutical Composition Obtained Thereof - A pharmaceutically acceptable peroxovanadium(v) amine product, DmpzH[VO(02)2](Dmpz)], and its oral as well as injectable use for the treatment of Diabetes mellitus, wherein the said therapeutically stable compound is obtained by reacting V205 or vanadate with hydrogen peroxide and the amine, dimethylpyrazole (Dmpz), at pH 5.5 and temperature 0-4° C. DmpzH[VO(02)2](Dmpz)] is thus poised as a versatile insulin mimic adapted for targeting insulin signaling, stimulating adipogenesis, abrogating insulin stimulated down stream signals thereby lowering the incidence of insulin resistance and type-2 diabetes. | 01-16-2014 |
20140024633 | Orally administrable gallium compositions and methods of use - Provided are pharmaceutical gallium compositions that are particularly useful for oral administration. The pharmaceutical compositions include solid, liquid, and paste formulations, which have high oral gallium bioavailability and are suitable for human and veterinary applications. The compositions comprise pharmaceutically acceptable gallium compounds, such as gallium maltolate, gallium 8-quinolinolonate, or gallium nitrate, together with certain viscosity-increasing agents, such as water-soluble forms of methylcellulose or carboxymethylcellulose. | 01-23-2014 |
20140031328 | Gallium compounds and methods of use to treat inflammatory bowel disease - Provided are formulations and methods for treating inflammatory bowel disease, including Crohn's disease, ulcerative colitis, and Johne's disease. The formulations provided comprise pharmaceutically acceptable gallium compounds; the methods provided comprise means of using such formulations in the treatment of inflammatory bowel disease and closely related disorders. | 01-30-2014 |
20140045809 | CORROLES FOR NEUROPROTECTION AND NEURORESCUE - Transition metal complexes of amphiphilic corroles, optical isomers and pharmaceutically acceptable salts thereof are useful for neuroprotection and neurorescue, particularly for treatment of diabetes and neurodegenerative diseases. The amphiphilic corrole is preferably a 5,10,15-tris-aryl- or 5,10,15-tris-CF | 02-13-2014 |
20140066418 | CONSTRUCTION MATERIAL PRESERVATIVE - The present invention provides a construction material preservative for wood and the like that retains preservative effects over a long period of time and continuously demonstrates those effects even at low concentrations even when using in combination with an insecticide. The construction material preservative contains a water-soluble silver-amino acid complex composed of 1 molar part of silver and 1 to 3 molar parts of amino acid. | 03-06-2014 |
20140080797 | SUBSTITUTED PORPHYRINS - Substituted metalloporphyrin compounds are described, along with pharmaceutical compositions containing the same, and methods of use thereof in protecting cells from oxidant-induced toxicity and pathological conditions such as inflammatory lung disease, neurodegenerative conditions, radiation injury, cancer, diabetes, cardiac conditions and sickle cell disease. Mn(III) porphyrins bearing oxygen atoms within side chains are particularly described. | 03-20-2014 |
20140088064 | PROCESS - The invention provides a method of forming an iron hydroxypyrone compound comprising reacting a hydroxypyrone with a non-carboxylate iron salt in an aqueous solution, and precipitating the iron hydroxypyrone compound from the aqueous solution having a pH of greater than 7. | 03-27-2014 |
20140088065 | COMPOSITION AND METHOD FOR AFFECTING OBESITY AND RELATED CONDITIONS - A composition including an effective amount of a compound including manganese [III] tetrakis (4-benzoic acid) porphyrin (MnTBAP), derivatives or analogs thereof to induce a reduction in body weight of a mammal or to improve insulin sensitivity of an obese mammal. A method including introducing an effective amount of a compound including manganese [III] tetrakis (4-benzoic acid) porphyrin (MnTBAP), derivatives or analogs thereof to a mammal to induce a reduction in body weight or to induce an increase in metabolism or insulin sensitivity of the mammal. | 03-27-2014 |
20140142079 | PLATINUM COMPOUNDS FOR TREATING CELL PROLIFERATIVE DISEASES, PREPARATION METHOD AND USE THEREOF - Disclosed are a class of platinum compounds with a leaving group of malonic acid derivatives containing amino and alkylamino, their pharmaceutically acceptable salts, their preparation methods and pharmaceutical composites comprising them. Disclosed also are for the uses of the compounds in the treatment of cell proliferative diseases, particularly for the treatment of cancers. The present platinum compounds have high water solubility and low toxicity. | 05-22-2014 |
20140155365 | COMPOSITIONS AND METHODS FOR CYTOPROTECTION - The present invention provides compositions and methods for cytoprotection. In particular, it provides zinc chelate compositions comprising at least one zinc ion and at least one aminothiol ligand. | 06-05-2014 |
20140155366 | PLATINUM ANTICANCER AGENTS - Described herein are novel platinum-based compounds and methods of using platinum-based compounds in the treatment of diseases, such as cancer, that are associated with cells expressing solute transporter proteins. | 06-05-2014 |
20140187527 | Macrocyclic Compounds And Metal Complexes For Bioimaging And Biomedical Applications - The present disclosure provides a novel class of macrocyclic compounds and their metal complexes formed with transition metal ion, lanthanide metal ions and other metal ions (e.g., Al, Ga, Y, In, Sn, Tl, Pb and Bi) and their applications in the fields of contrast agents, artificial nucleases, fluorescence probes, nuclear medicines and other biomedical applications in the therapeutics or diagnostics. | 07-03-2014 |
20140200204 | COMBINATIONS OF CORROLES AND STATINS - Embodiments of the invention relate to methods of treatment a cardiovascular disease in a patient comprising administering an effective amount of a statin or a pharmaceutically acceptable salt thereof in combination with an effective amount of a transition metal complex of a corrole, an optically active isomer thereof or a pharmaceutically acceptable salt thereof. Further embodiments refer to pharmaceutical compositions comprising a statin and a corrole. | 07-17-2014 |
20140303134 | PLATINUM COMPOUNDS THAT INHIBIT CONSTITUTIVE STAT3 SIGNALING AND INDUCE CELL CYCLE ARREST AND APOPTOSIS OF MALIGNANT CELLS - The subject invention concerns a compound and compositions having activity as an inhibitor of Stat3 protein and methods of using the compound and compositions. In one embodiment, a compound of the invention has the structure shown in formula I, formula II, or formula III. The subject invention also concerns methods of using the compounds and compositions of the invention. | 10-09-2014 |
20150038477 | ORALLY ADMINISTRABLE GALLIUM COMPOSITIONS AND METHODS OF USE - Provided are pharmaceutical gallium compositions that are particularly useful for oral administration. The pharmaceutical compositions include solid, liquid, and paste formulations, which have high oral gallium bioavailability and are suitable for human and veterinary applications. The compositions comprise pharmaceutically acceptable gallium compounds, such as gallium maltolate, gallium 8-quinolinolonate, or gallium nitrate, together with certain viscosity-increasing agents, such as water-soluble forms of methylcellulose or carboxymethylcellulose. | 02-05-2015 |
20150051184 | HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN - Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions. | 02-19-2015 |
20150320863 | PROCESS OF FORMING IRON HYDROXYPYRONE COMPOUNDS - The invention provides a method of forming an iron hydroxypyrone compound comprising reacting a hydroxypyrone with a non-carboxylate iron salt in an aqueous solution, and precipitating the iron hydroxypyrone compound from the aqueous solution having a pH of greater than 7. | 11-12-2015 |
20160016976 | GOLD COMPLEXES - Gold (I) hydroxide complexes of the form Z—Au—OH and digold complexes of the form Z—Au-(μOH)—Au—Z where groups Z are two electron donors are provided. The groups Z may be carbenes, for example nitrogen containing heterocyclic carbenes (NHCs), phosphines or phosphites. The complexes can be used as catalysts, for example in reactions such as hydration of nitriles, skeletal arrangement of enynes, alkoxycyclisation of enynes, alkyne hydration, the Meyer-Shuster reaction, 3,3′ rearrangement of allylic acetates, cyclisation of propargylic acetates, Beckman rearrangements and hydroamination. The complexes can be used in medicine, for example in the treatment of cancer. | 01-21-2016 |
20160068557 | PLATINUM COMPOUNDS, COMPOSITIONS, AND USES THEREOF - The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one reacting group for reacting with a functional group on a protein, engineered protein, antibody, antibody fragment, peptide, agonist, antagonist, aptamer or ligand which may be capable of recognizing a selected target cell population, and/or derivatives/analogs/mimics thereof. | 03-10-2016 |
20160130291 | PLATINUM COMPLEXES AS ANTICANCER AGENTS - Compounds comprising a Pt(II) metal center and S-containing ligands in accordance to Formula I as anticancer agents. Methods of treating cancer comprising administering the compounds are also provided. | 05-12-2016 |
20160151384 | NEW MODUS OF ADMINISTRATION OF IRON, AND NEW FORMULATIONS ADAPATED FOR THE SAID GOAL | 06-02-2016 |
20160249605 | ANTIBACTERIAL RESIN COMPOSITION | 09-01-2016 |