Class / Patent application number | Description | Number of patent applications / Date published |
506007000 |
METHOD OF SCREENING A LIBRARY
| 6458 |
506002000 |
METHOD SPECIALLY ADAPTED FOR IDENTIFYING A LIBRARY MEMBER
| 1607 |
506013000 |
LIBRARY, PER SE (E.G., ARRAY, MIXTURE, IN SILICO, ETC.)
| 1195 |
506033000 |
APPARATUS SPECIALLY ADAPTED FOR USE IN COMBINATORIAL CHEMISTRY OR WITH A LIBRARY
| 631 |
506023000 |
METHOD OF CREATING A LIBRARY (E.G., COMBINATORIAL SYNTHESIS, ETC.)
| 531 |
506001000 |
DIRECTED MOLECULAR EVOLUTION OF MACROMOLECULES (E.G., RNA, DNA, PROTEINS, ETC.)
| 126 |
506041000 |
TAG OR LABEL SPECIALLY ADAPTED FOR COMBINATORIAL CHEMISTRY OR A LIBRARY (E.G., FLUORESCENT TAG, BAR CODE, ETC.) | 5 |
20120270757 | SITE-SPECIFIC LABELING OF AFFINITY TAGS IN FUSION PROTEINS - The present invention provides methods and fluorescent compounds that facilitate detecting and labeling of a fusion protein by being capable of selectively binding to an affinity tag. The fluorescent compounds have the general formula A(B)n, wherein A is a fluorophore, B is a binding domain that is a charged chemical moiety, a protein or fragment thereof and n is an integer from 1-6 with the proviso that the protein or fragment thereof not be an antibody or generated from an antibody. The present invention provides specific fluorescent compounds and methods used to detect and label fusion proteins that contain a poly-histidine affinity tag. These compounds have the general formula A(L)m(B)n wherein A is a fluorophore, L is a linker, B is an acetic acid binding domain, m is an integer from 1 to 4 and n is an integer from 1 to 6. | 10-25-2012 |
20140038856 | Site-specific labeling of affinity tags in fusion proteins - The present invention provides methods and fluorescent compounds that facilitate detecting and labeling of a fusion protein by being capable of selectively binding to an affinity tag. The fluorescent compounds have the general formula A(B)n, wherein A is a fluorophore, B is a binding domain that is a charged chemical moiety, a protein or fragment thereof and n is an integer from 1-6 with the proviso that the protein or fragment thereof not be an antibody or generated from an antibody. The present invention provides specific fluorescent compounds and methods used to detect and label fusion proteins that contain a poly-histidine affinity tag. These compounds have the general formula A(L)m(B)n wherein A is a fluorophore, L is a linker, B is an acetic acid binding domain, m is an integer from 1 to 4 and n is an integer from 1 to 6. The acetic acid groups interact directly with the positively charged histidine residues of the affinity tag to effectively label and detect a fusion protein containing such an affinity tag when present in an acidic or neutral environment. | 02-06-2014 |
20140057809 | Miniaturized microparticles - A system and method for forming encoded microparticles is described. One embodiment includes an encoded microparticle, the microparticle comprising a plurality of segments aligned along an axis, wherein the plurality of segments define a code for the microparticle; and an outer cuboid encapsulating the plurality of segments, wherein the plurality of segments are detectable through the outer cuboid. | 02-27-2014 |
20140349893 | LABELING OF IMMOBILIZED PROTEINS USING DIPYRROMETHENEBORON DIFLUORIDE DYES - The invention describes methods for labeling or detecting of immobilized poly(amino acids), including peptides, polypeptides and proteins, on membranes and other solid supports, using fluorescent dipyrrometheneboron difluoride dyes. Such immobilized poly(amino acids) are labeled or detected on blots or on arrays of poly(amino acids), or are attached to immobilized aptamers. | 11-27-2014 |
20160122813 | Methods And Kits Using Extended Rhodamine Dyes - Extended rhodamine compounds exhibiting favorable fluorescence characteristics having the structure | 05-05-2016 |
506043000 |
MISCELLANEOUS | 2 |
20080293596 | Systems and Methods for the Generation of Crystalline Polymorphs - The present invention relates to systems and methods for generating polymorphs of compounds. In particular, the present invention provides high throughput systems and methods for generating and identifying new crystalline polymorphs that find use as improved drugs, pigments, explosives, nonlinear optical crystals, solid-state reactive compounds, and other polymorphic materials. | 11-27-2008 |
20140274814 | Removable fluidics structures for microarray, microplates, sensor arrays, and other removable media - A removable microfluidics structure comprising at least one actuated fluid delivery element, wherein the actuated fluid delivery element is a pump element of a valve element configured to control fluid delivery to or from a removable media detachably coupled with the removable microfluidics structure based on an actuation force. The actuation force is an external actuation force or an internal actuation force. The removable microfluidics structure may include an electromechnical actuator for providing the actuation force, such as a solenoid, a solenoid with an ferromagnetic core or a piezoelectric actuator. The removable microfluidics structure may further include a coupling mechanism for detachably coupling the removable microfluidics structure with the removable media, such as a cell array, such that when the microfluidics structure couples with the removable media, the microfluidics structure controls fluid delivery to or from a cell of the cell array. | 09-18-2014 |
506042000 |
LINK OR SPACER SPECIALLY ADAPTED FOR COMBINATORIAL CHEMISTRY OR A LIBRARY (E.G., TRACELESS LINKER, SAFETY-CATCH LINKER, ETC.) | 1 |
20090239770 | DETECTION OLIGOMER AND METHOD FOR CONTROLLING QUALITY OF BIOCHIP USING DETECTION OLIGOMER - A detection oligomer and method for controlling the quality of a biochip using the detection oligomer are provided. The detection oligomer includes a template having a first and second end and having a sequence that is complementary to a specific sequence of an oligomer, and a hairpin connected to the first end of the template. | 09-24-2009 |