Entries |
Document | Title | Date |
20080241957 | Sample analyzer, sample analyzing method, and computer program product - A sample analyzing method comprising: aspirating a sample from a sample container; preparing a plurality of measurement samples from the aspirated sample; sequentially measuring the plurality of prepared measurement samples; obtaining a plurality of measurement data for the respective measurement samples; and obtaining an analysis result of a predetermined item of the sample based on the plurality of measurement data, is disclosed. A sample analyzer and a computer program product are also disclosed. | 10-02-2008 |
20090093065 | ASPIRATING AND DISPENSING SMALL VOLUMES OF LIQUIDS - A metering device for aspirating and dispensing a liquid includes a housing; a pumping medium, preferably a gas containing chamber contained within the housing; a channel having a proximate end in fluid communication with the chamber and a distal end in fluid communication with an external environment; a heat or cold source providing a source of heat or cold to the gas containing chamber; and a temperature sensor for measuring the temperature inside the chamber. In a preferred embodiment, the device further includes a pressure sensor for measuring gas pressure inside the chamber, or multiple chambers. A method for aspirating and dispensing a liquid includes: providing a metering device for aspirating and dispensing a liquid that includes a housing; a gas containing chamber contained within the housing, the chamber; a channel having a proximate end in fluid communication with the chamber and a distal end in fluid communication with an external environment; a heat or cold source providing a source of heat or cold to the gas containing chamber; and a temperature sensor for measuring the temperature inside the chamber; providing a source of liquid to be aspirated; bringing the distal end of the channel into contact with the liquid; cooling the gas containing chamber with the heat or cold source to aspirate a first volume of liquid into the device; and heating the gas containing chamber to dispense a second volume of liquid out of the device. In a preferred embodiment, the metering device is a used in a diagnostic analyzer for determining the presence of one or more analytes in a sample. | 04-09-2009 |
20090098659 | METHOD OF PATTERNING PARTICLES ON AN ARBITRARY SUBSTRATE AND CONDUCTING A MICROFLUIDIC INVASION ASSAY - A method is provided for sequentially patterning different particle populations on spatially defined regions in microfluidic device. The microfluidic device has a channel and a plurality of access ports therein. Each access port has an input and an output communicating with the channel. The method includes the step of depositing a drop of a first suspension on the input of a first access port. The first suspension includes a plurality of particles. A drop of a second suspension is deposited on the input of a second access port. The second suspension includes a plurality of particles. The particles in the first and second suspensions settle onto and are patterned along corresponding spaced portions of the channel. | 04-16-2009 |
20090137062 | ANALYSIS SYSTEM AND METHOD FOR THE ANALYSIS OF A BODY FLUID SAMPLE FOR AN ANALYTE CONTAINED THEREIN - Analysis system and method for the analysis of a body fluid sample for an analyte contained therein are disclosed. The analysis system has a dosing station for dosing a liquid into a test element through a sample supply opening, which reacts with a reagent system present in a sample analysis channel of the test element. The analysis system also has a measurement station for measuring a measurement variable characteristic of the reaction at the measuring zone of a test element for the analytical result. The test element also includes a separate flushing liquid supply opening and a flushing liquid collection chamber which are in fluid communication to one another via a flushing liquid channel. The flushing liquid channel and the sample analysis channel differ from one another in such a manner that a liquid flowing through the flushing liquid channel does not reach the measuring zone. | 05-28-2009 |
20090155927 | MICROREACTOR AND METHOD OF LIQUID FEEDING MAKING USE OF THE SAME - A microreactor capable of reaction between a sample and a mixed reagent containing a mixture of multiple reagents, which microreactor avoids the interposition of air between driving solution and reagents and realizes high-precision controlling of the timing of mixing of reagents and other liquids, the mixing ratio of liquids, the pressure for liquid feeding, etc. Further, there is provided a method of liquid feeding making use of the same. Accordingly, a flow path branched at the position of an inlet from a flow path through which an opening communicating with an external pump communicates with the inlet is provided with an air evacuation flow path with its terminal open outward. Further, the flow path resistance of the air evacuation flow path for a liquid is made greater than the flow path resistance, for the liquid, of a flow channel from the reagent storage chamber to a reagent feed-out flow path. | 06-18-2009 |
20090162940 | Specimen Analysis Tube - A method and apparatus for analyzing a fluid sample. More particularly, this relates to a specimen analysis tube ( | 06-25-2009 |
20090162941 | Methods and Devices, Including Stoppers Comprising an Internal Recess with Particular Hydrophilicity Characteristics, for Limiting Air Ingestion During Sample Extraction - The present invention relates to methods and devices for air ingestion prevention. The invention provides a stopper or plug with one or more conduits and a recess that prevents air ingestion during outlet of a liquid from a liquid container covered with the stopper. | 06-25-2009 |
20090162942 | Method and apparatus for sample preparation in an automated discrete fluid sample analyzer - An automated discrete fluid sample analyzer includes a sample preparation module. The sample preparation module includes a well configured to receive a sample deposited by a pipettor and a sample preparation device in fluid communication with the well. The fluid sample is transferred from the well to the sample preparation device, and the sample preparation device prepares the fluid sample. The pipettor then aspirates the prepared fluid sample. The prepared fluid sample may be transferred from the sample preparation device back to the well, and the pipettor aspirates the prepared fluid sample from the well. In one embodiment, the sample preparation device includes a receptacle having a catalyst disposed therein. The catalyst may include a noble metal catalyst, such as cadmium. In another embodiment, the sample preparation device includes an ultraviolet lamp configured to apply ultraviolet light to the fluid sample. In yet another embodiment, the sample preparation device includes a heater configured to heat the fluid sample. In another aspect, a fluid sample is agitated to place more of the fluid sample in contact with the catalyst. | 06-25-2009 |
20090176316 | Automated fluid handling cartridge, fluid processing system, and methods - The present invention relates to a cartridge, system, and methods that can be used for automated handling of fluids, such as blood. The cartridge can be configured to obtain a fluid sample from a sealed container, e.g., a septum sealed container. The system can be configured to handle the cartridge for operations such as obtaining a sample and/or dispensing the sample from the cartridge into, for example, a microtiter plate. The method of the invention can employ the cartridge or system of the invention. | 07-09-2009 |
20090253216 | Delivery and Sensing of Metered Amounts of Liquid Materials - A liquid delivery apparatus is provided for depositing liquid materials onto prescribed areas. The apparatus includes a sensing and delivery pin and a photo sensor. The apparatus is sized to deliver a droplet of liquid material to the surface of a target area without coming into contact with the target surface. The apparatus is also capable of drawing geometric features, such as lines and grids of liquid material. The photo sensor measures the intensity of light during a processing cycle. Measured reflected-light intensity can be compared in real-time to a reference curve which is based on test process cycles representing the light intensity expected when the process proceeds in the preferred fashion to produce a normal spot having an expected droplet size. The light intensity measurements can also be fitted with a mathematical function such as an asymmetric double sigmoidal curve. | 10-08-2009 |
20090325309 | Reagent Delivery System, Dispensing Device and Container for a Biological Staining Apparatus - The invention concerns reagent delivery system for an apparatus for processing of biological samples arranged on microscope slides, comprising a reagent section having one or more reagent containers; a slide section in which at least one microscope slide is arranged; a probe for dispensing a portion of reagent onto a predetermined microscope slide, and means for handling the probe. The probe comprises a continuous prove tubing element extending through a rigid probe member and connecting the probe tip to a pneumatic pressure regulation device. The reagent containers are adapted for cooperation with the probe tip. In this manner a high though-put and a very low carry over of fluid residues is achieved since there is no assembled parts making up the inside volume of the probe in which the fluid may be retained. | 12-31-2009 |
20100009459 | METHOD AND MICROFLUIDIC DEVICE FOR COMBINING REACTION COMPONENTS CONTAINED IN LIQUIDS - The invention relates to a method and a microfluidic device for combining reaction components contained in liquids. The method comprises the steps: application of at least one first liquid filament containing a first reaction component on a first carrier substrate; application of at least one second liquid filament containing a second reaction component on a second carrier substrate; positioning of the two carrier substrates relative to each other at a predetermined distance such that the liquid filaments face each other; and bringing at least one of the at least one first liquid filament into contact with at least one of the at least one second liquid filament by creating at least one connecting point of the respective first and second liquid filaments. A microfluidic device for combining reaction components contained in liquids comprises two carrier substrates each being adapted for accommodating at least one first and at least one second liquid filament, wherein the liquid filaments are preferably each accommodated in a receiving means which is comprised in the carrier substrate. | 01-14-2010 |
20100009460 | Multifunctional vacuum manifold - A laboratory device design particularly for a multiplate format that includes a manifold wherein the position of the plate is not a function of gasket compression or vacuum rate applied. In one embodiment, the device has a modular design, wherein one or more removable inserts, preferably with different functionalities can be positioned between a base component and a collar component. The particular insert(s) chosen depend on the desired sample preparation or assay to be carried out. The insert(s) are stacked and are positioned between the base and collar as a unit, so that the stack within the manifold does not move during evacuation of the vacuum chamber. The consistent position of the insert(s) facilitates using vacuum sample processing with automated liquid handlers. | 01-14-2010 |
20100151586 | DOSING DEVICE FOR DOSING A FLUID INTO A RECEIVING CHANNEL OF A TEST ELEMENT FOR ANALYZING BODILY FLUIDS AND METHOD THEREOF - Methods for dosing a fluid into a receiving channel of a test element using a dosing device are disclosed. The dosing device comprises a dosing chamber in fluid connection with a dosing tube having a dosing tip, an optional dosing element extending at least partially into the dosing chamber, a dosing control device, and a movement device for moving the dosing tube and the test element closer to one another. The movement device is actuated to move the dosing tube relative to the test element. The dosing control device is actuated to discharge a fluid into the receiving channel. During the discharge, a fluid bridge forms between the dosing tip and the receiving channel. At the end of the discharge, at least some of the fluid reaches the receiving channel through suction force. A disposable cartridge may be used for dosing a fluid into such a receiving channel. | 06-17-2010 |
20100184235 | WELL PLATE FOR HOLDING A SAMPLE DURING ANALYSIS AND A METHOD FOR PREPARING A SAMPLE FOR ANALYSIS - A well plate ( | 07-22-2010 |
20110027906 | METERING DOSES OF SAMPLE LIQUIDS - A device and method of metering and mixing a dose of a sample liquid with a diluent liquid includes introducing a sample liquid into a channel defined in a housing. The housing defines a pocket open to the channel and sized to both collect a metered dose of the sample liquid, and to retain the collected dose by capillary force when the channel is emptied. The sample liquid is then removed from the channel under conditions that enable retention of the collected, metered dose of the sample liquid in the pocket. Following a cleaning step, a volume of diluent liquid is introduced into the channel to induce diffusion and mixing of the diluent liquid with the dose of sample liquid to form a mixture. | 02-03-2011 |
20110086433 | Microfluidic chip - A microfluidic chips ( | 04-14-2011 |
20110129941 | Method of Producing Polymeric Particles With Selected Size, Shape, Morphology and Composition - The present invention provides a method and apparatus for producing polymeric particles with pre-designed size, shape, morphology and composition, and more particularly the present invention uses a microfluidic polymerization reactor for producing same. The present invention disclosed herein provides a process for producing polymer particles with pre-selected shapes. The method includes injecting a first fluid comprising a polymerizable constituent with a controlled flow rate into a microfluidic channel and injecting a second fluid with a controlled flow rate into the microfluidic channel in which the second fluid mixes with the first fluid, the second fluid being immiscible with the first fluid so that the first fluid forms into droplets in the microfluidic channel. The microfluidic channel has pre-selected dimensions to give droplets of pre-selected size, morphology and shape. The microfluidic channel is sufficiently long so that the droplets have a sufficiently long residence time in the channel so that they polymerize or otherwise harden into droplets of pre-selected size and shape. | 06-02-2011 |
20110136252 | Integrated Microfluidics for Parallel Screening of Chemical Reactions - A microfluidic device allows for different reactions to be conducted in parallel with the use of nanoliter quantities of reagents. | 06-09-2011 |
20110143452 | CRYOGENIC VIAL - Provided is a cryogenic vial for storing at least one sample, the vial including a pipette, a cap assembly, and a container having at least one opening in a body portion of the container to allow liquid and/or gas to enter and/or exit the vial to balance the pressure between the inside of vial and the outside environment. The cryogenic vial allows for reduced processing time and minimizes the chance a sample may be lost or damaged while being processed. | 06-16-2011 |
20110151578 | VALVES AND OTHER FLOW CONTROL IN FLUIDIC SYSTEMS INCLUDING MICROFLUIDIC SYSTEMS - Articles and methods for controlling flow in fluidic Systems, especially in microfluidic Systems, are provided. A microfluidic System includes a configuration such that the actuation of a single valve can allow the switching of fluids from a first fluid path (e.g., a first channel section) to a second fluid path (e.g., a second channel section). This may be achieved by incorporating a valve ( | 06-23-2011 |
20110171748 | Device And Method For Making Discrete Volumes Of A First Fluid In Contact With A Second Fluid, Which Are Immiscible With Each Other - Various embodiments described in the application relate to an apparatus, system, and method for generating, within a conduit, discrete volumes of one or more fluids that are immiscible with a second fluid. The discrete volumes can be used for biochemical or molecular biology procedures involving small volumes, for example, microliter-sized volumes, nanoliter-sized volumes, or smaller. The system can comprise an apparatus comprising at least one conduit operatively connected to one or more pumps for providing discrete volumes separated from one another by a fluid that is immiscible with the fluid(s) of the discrete volumes, for example, aqueous immiscible-fluid-discrete volumes separated by an oil. | 07-14-2011 |
20110183433 | PIPETTE TIPS - Disclosed here are pipette tips useful for acquiring or dispelling liquids, and include one or more design that may increase fluid delivery precision and/or accuracy, and may reduce certain repetitive motions. | 07-28-2011 |
20110223682 | SAMPLE ANALYZER AND REAGENT MANAGEMENT METHOD - A sample analyzer for performing analysis regarding a predetermined measurement item by using a combination of at least a first reagent and a second reagent, the sample analyzer comprising: a reagent container holder configured to hold a first reagent container which contains the first reagent and which includes a first storage medium, and a second reagent container which contains the second reagent and which includes a second storage medium; a writer configured to write information into the first storage medium and the second storage medium; and a controller configured to control the writer to write, into the first storage medium of the first reagent container, identification information for identifying the second reagent container which is paired with the first reagent container is disclosed. A reagent management method is also disclosed. | 09-15-2011 |
20110236990 | Automatic Analyzer and Sample Dispensing Method for the Automatic Analyzer - An automatic analyzer capable of avoiding carry-over between samples, and a sample dispensing method, are provided. To that end, an automatic analyzer ( | 09-29-2011 |
20110244593 | METHOD AND APPARATUS FOR SELECTIVELY ADMIXING REAGENTS IN A SUBSTANTIALLY UNDILUTED BIOLOGIC FLUID SAMPLE ANALYSIS - A biologic fluid sample analysis method and system is provided that includes a reagent depository, and analysis chamber, a biologic fluid transfer system, and a programmable analyzer. The reagent depository has a plurality of reagent deposits, and each reagent deposit located at a position within the depository independent of the other reagent deposits. The analysis chamber is adapted to quiescently hold a biologic fluid sample and one or more reagents during analysis. The biologic fluid transfer system has at least one fluid transfer device. The programmable analyzer is adapted to control the biologic fluid transfer system to acquire a volume of sample from a sample reservoir, dispense a volume of the sample into the reagent depository, acquire a volume of sample and reagent from the reagent depository, and to transfer the sample and reagent to the analysis chamber, and to analyze the combined sample and reagent. | 10-06-2011 |
20110281373 | MULTI-POSITION SAMPLING VALVE - The invention relates to a sampling valve, for taking samples of fluid from a common collecting vessel in order to perform a plurality of analyses using reagents. The valve of the invention comprises two members that are movable relative to each other, comprising a sampling member having sampling loops, each intended to receiving an aliquot of fluid, and a connection member capable of assuming at least three functional positions relative to the sampling member. These three positions enable the delayed access to two separate sampling circuits in order to fill them and to dispense reagents to the loops that make them up. | 11-17-2011 |
20110300639 | Improved Sample Injection Port for Laminated Devices - Contemplated diagnostic test containers and methods include an adapter configured to sealingly receive and retain a positive displacement pipette tip to so form a fluid-tight seal for the container during at least part of the diagnostic test. Most preferably, the entire container is flexible and the container and adapter are single-use disposable and are usable with known commercially available positive displacement pipette tips. | 12-08-2011 |
20120015447 | Method for operating an analytical apparatus - A method for operating an analytical apparatus for determining concentration of an analyte, especially an oxidizable substance, in a sample liquid, comprises the steps of: placing the analytical apparatus in maintenance operation; operating a metering system, which includes a pump, especially a peristaltic pump, and a supply line, for metering single volume units of a sample liquid from a source via the supply line into a reactor, wherein there exists in the reactor a temperature, which is greater than the boiling temperature of the sample liquid, so that a volume unit of the sample liquid metered into the reactor transforms at least partially into the gas phase following entry into the reactor, especially due to heat transfer from contact with a surface within the reactor, especially directly after contact with the surface within the reactor, and wherein a carrier gas is flowing through the reactor; registering at least one measuring transducer signal for detection of the transforming of the volume unit of the sample liquid into the gas phase, and deriving, with application of the measuring transducer signal, a signal correlated with an instantaneous operating state of the metering system. | 01-19-2012 |
20120021529 | Micro-Valve and Micro-Fluidic Device Using Such - A micro-valve ( | 01-26-2012 |
20120034705 | FLUID PROCESSING AND CONTROL - A fluid control and processing system for controlling fluid flow among a plurality of chambers comprises a body including a fluid processing region continuously coupled fluidicly with a fluid displacement region. The fluid displacement region is depressurizable to draw fluid into the fluid displacement region and pressurizable to expel fluid from the fluid displacement region. The body includes at least one external port. The fluid processing region is fluidicly coupled with the at least one external port. The fluid displacement region is fluidicly coupled with at least one external port of the body. The body is adjustable with respect to the plurality of chambers to place the at least one external port selectively in fluidic communication with the plurality of chambers. | 02-09-2012 |
20120040472 | SYSTEM AND METHOD FOR AUTOMATED GENERATION AND HANDLING OF LIQUID MIXTURES - The invention relates to a system ( | 02-16-2012 |
20120058571 | METHODS, DEVICES, AND SYSTEMS FOR FLUID MIXING AND CHIP INTERFACE - In one aspect, the present invention provides methods, devices, and systems for ensuring that multiple components of a mixture are fully mixed in a continuous flow microfluidic system while ensuring that mixing between segments flowing through the chip is minimized. In some embodiments, the present invention includes mixing fluids in a droplet maintained at the tip of a pipette before the mixture is introduced to the microfluidic device. In another aspect, the present invention provides a pipette tip having a ratio of an outside diameter to an inside diameter that provides sufficient surface area for a droplet comprising up to the entire volume of the liquid to suspend from the pipette tip intact. In yet another aspect, the present invention provides methods, devices, and systems for delivering a reaction mixture to a microfluidic chip comprising a docking receptacle, an access tube and a reservoir. | 03-08-2012 |
20120100630 | MIXER WITH ZERO DEAD VOLUME AND METHOD FOR MIXING - The invention relates to a micro fluidics system ( | 04-26-2012 |
20120122232 | CASSETTE FOR SAMPLE PREPARATION - A cassette for preparing a sample is disclosed herein. The cassette includes a housing, which encloses the structures and the processes used to prepare the sample. | 05-17-2012 |
20120156800 | LIQUID FEEDING SYSTEM FOR MICROCHIP, SAMPLE DETECTION DEVICE, AND LIQUID FEEDING METHOD FOR LIQUID FEEDING SYSTEM FOR MICROCHIP - A liquid feeding system for a microchip performs: a first liquid feeding step in which a sample liquid in a sample liquid containing section is fed in the direction to a primary containing section via a reaction field; a second liquid feeding step in which, after the first liquid feeding step, the sample liquid is fed from the primary containing section in the direction to the reaction field; and a third liquid feeding step in which, after the second liquid feeding step, the feedings of the sample liquid from and to the reaction field and the primary containing section a rear side gas-liquid boundary face of the sample liquid in the first liquid feeding step and the front side and rear side gas-liquid boundary faces of the sample liquid in the second and third liquid feeding steps do not pass through the reaction field. | 06-21-2012 |
20120156801 | AUTOMATIC ANALYZER AND ANALYSIS METHOD FOR USE IN THE SAME - An automatic analyzer performs for plural kinds of reagents dispensed at different timings. The automatic analyzer includes a plurality of reaction cells, a reaction cell moving unit for moving the plurality of reaction cells at a certain cycle; a sample dispensing unit for dispensing a sample into a reaction cell and a reagent dispensing unit for dispensing reagents to be added during a sample-reagent reaction process at different timings. | 06-21-2012 |
20120178179 | DIAGNOSTIC CARTRIDGE AND CONTROL METHOD FOR DIAGNOSTIC CARTRIDGE - Discussed are a diagnostic cartridge and a control method for the diagnostic cartridge. The cartridge includes a sample port through which a sample is injected, a first chamber moving the sample injected from the sample port, a second chamber moving a substrate solution, a first membrane formed at a distal end of the first chamber to function as a valve for preventing other substances from being injected into the first chamber after the sample is completely moved, and a second membrane formed at a distal end of the second chamber to function as a valve for preventing other substances from being injected into the first chamber after the substrate solution is completely moved. | 07-12-2012 |
20120190128 | MODULAR MICROFLUIDIC SAMPLE PREPARATION SYSTEM AND METHOD OF MIXING AND DELIVERING A SAMPLE FLUID - A modular microfluidic sample preparation system ( | 07-26-2012 |
20130017621 | METHODS AND SYSTEMS PROVIDING REAGENT MIXING - Disclosed are methods and systems adapted to provide mixing of a liquid reagent in an automated clinical analyzer. The methods include aspirating an air separator (e.g., an air slug) into the interior of a probe. A relatively small volume of reagent liquid is also aspirated into the probe adjacent to the air separator; the volume of liquid reagent being entirely contained within the probe. The volume of liquid reagent may be repeatedly aspirated and dispensed at a relatively high frequency to accomplish reagent mixing in the reagent container. Improved sample and reagent mixing may be promoted using a similar method. Systems carrying out the methods are provided, as are other aspects. | 01-17-2013 |
20130078736 | SYSTEM AND APPARATUS FOR REACTIONS - This disclosure provides systems, apparatuses, and methods for liquid transfer and performing reactions. In one aspect, a system includes a liquid transfer device having a housing having a pipette tip and a plunger assembly; and a reaction chamber, wherein the housing of the liquid transfer device is configured to sealably engage with the reaction chamber. In another aspect, a liquid transfer device including a housing having a pipette tip; and a plunger assembly disposed within the housing and the pipette tip, wherein a portion of the plunger assembly is configured to engage a fluid reservoir such that the plunger assembly remains stationary relative to the fluid reservoir and the housing moves relative to the plunger assembly. | 03-28-2013 |
20130109106 | SYSTEM FOR SELECTIVELY PROCEEDING A SAMPLE | 05-02-2013 |
20130149791 | BIOCHIPS AND METHODS FOR INJECTING A SPECIFIC MICROVOLUME OF SAMPLE - A biochip is provided. The biochip may include a reaction chamber containing a reagent, an injection channel including a sample injection channel to inject the sample into the reaction chamber and a sample bypass channel preventing the sample from being injected into the reaction chamber, and an exhaust channel connected to both of the sample exhaust channel and the sample bypass channel. | 06-13-2013 |
20130224878 | BIOCHIP WELL, SEALED WELL ASSEMBLY, CARTRIDGE THEREFOR, AND APPARATUS AND METHODS FOR OPENING SEALED WELLS - A biochip well is disclosed, including a vessel containing a well therewithin, the vessel forming at least base and side walls of the well and defining at least one aperture giving access to the well, and further including retaining means for holding a biochip at a predetermined position within the well, the well including a laterally offset region into which the biochip does not protrude when held at the predetermined position by the retaining means. Also disclosed are sealed well assemblies and apparatus and methods for opening sealed wells. | 08-29-2013 |
20130252345 | Specimen Collection Container Having a Transitional Fill-Volume Indicator Indicating Extraction Method - A specimen collection container having a transitional fill-volume indicator is disclosed. The specimen collection container includes an open top end, a closed bottom end, and a sidewall extending therebetween defining an interior. The specimen collection container includes a transitional fill-volume indicator adjacent the sidewall, such that the container defines a first volumetric interior defined by the sidewall between the closed bottom end and the transitional indicator. The specimen collection container also defines a second volumetric interior defined by the sidewall between the closed bottom end and a portion of the sidewall disposed above the transitional indicator. The first volumetric interior is adapted to allow extraction of a specimen therefrom by a first extraction process, and the second volumetric interior is adapted to allow extraction of a specimen therefrom by either the first extraction process or a second extraction process, the second extraction process being different than the first extraction process. | 09-26-2013 |
20130267038 | MICROPLATE GUIDE FOR A PIPETTE - Microplate guide for a pipette, said guide comprising means for selecting the type of the microplate, the mode of dispensing and the dispensing direction, as well as means for indicating the next target for dispensing on the display of the pipette prior to each pipetting operation, and a method for guiding a pipetting operation, said method comprising the steps of selecting the type of microplate, selecting the mode of dispensing, and selecting the dispensing direction, followed by displaying on the display of the pipette the next target for dispensing prior to each pipetting operation. | 10-10-2013 |
20130288382 | Electric Pipetting Apparatus, and Method for Operating an Electric Pipetting Apparatus - The invention relates to a pipetting apparatus, for pipetting a fluid sample in accordance with at least one mode of operation of the pipetting apparatus, which is controlled by an operating parameter set, which is associated with a corresponding mode of operation, wherein the electric control device of the pipetting apparatus is designed to automatically store the at least one parameter value set determined by the user to be the at least one historic parameter value set for this mode of operation in the memory device, and is designed to provide, after the operating parameter set for this mode of operation has changed, the at least one automatically stored historic parameter value set for this mode of operation again for the subsequent control of the at least one, same, pipetting process. The invention also relates to a method for operating the pipetting apparatus. | 10-31-2013 |
20130337578 | MICROFLUIDIC DEVICE WITH AUXILIARY AND BYPASS CHANNELS - The invention is directed to a microfluidic device having a flow inlet and outlet, generally defining a flow direction. A bypass channel ( | 12-19-2013 |
20130344617 | SAMPLE METERING - A sample metering device for a liquid sample comprises at least one capillary passage with an inlet and an outlet; a side passage extending from the capillary passage part way along the length thereof and leading to an outlet; a fluid application region for receiving a liquid sample to be tested, for entry to the capillary passage via the inlet; first sealing means operable releasably to seal the outlet of the capillary passage; and second sealing means operable releasably to seal the outlet of the side passage. | 12-26-2013 |
20140011291 | LATERAL CAVITY ACOUSTIC TRANSDUCER BASED MICROFLUIDIC SWITCH - A microfluidic switching device that includes an upstream microfluidic channel configured to contain a liquid having particles therein and a plurality of outlet channels coupled to the upstream microfluidic channel at a junction. A dead-end side channel or LCAT is oriented generally perpendicular to the upstream microfluidic channel and coupled to the upstream microfluidic channel at the junction, the dead-end side channel having a gas contained therein. The device includes a transducer configured to apply an external source of acoustic energy. Actuation of the transducer effectuates symmetrical oscillation of a gas/liquid boundary at the junction. Preferably, the junction comprises a bifurcation with two outlets. Further, the LCAT has a leading edge and a trailing edge and wherein the trailing edge of the LCAT is substantially aligned with the bifurcation. | 01-09-2014 |
20140017806 | MICROFLUIDIC STRUCTURE, MICROFLUIDIC DEVICE HAVING THE SAME AND METHOD OF CONTROLLING THE MICROFLUIDIC DEVICE - A microfluidic structure in which a plurality of chambers arranged at different positions are connected in parallel and into which a fixed amount of fluid may be efficiently distributed without using a separate driving source, and a microfluidic device having the same. The microfluidic device includes a platform having a center of rotation and including at least one microfluidic structure. The microfluidic structure includes a sample supply chamber configured to accommodate a sample, a plurality of first chambers arranged in a circumferential direction of the platform at different distances from the center of rotation of the platform, and a plurality of siphon channels, each of the siphon channels being connected to a corresponding one of the first chambers. | 01-16-2014 |
20140024135 | MICRO PLATE TREATING DEVICE AND MICRO PLATE TREATING METHOD - An object is to provide a micro plate treating device and micro plate treating method capable of handling a larger number of kinds of solution or suspensions or a larger volume of solutions or suspensions per work area by use of a normalized micro plate without enlarging the scale of the device. The micro plate treating device comprises a micro plate having wells arranged in a matrix form, one or two or more nozzle heads each having nozzles capable of sucking and discharging a fluid and arranged in a matrix form, and moving means capable of moving relatively an interval between the micro plate and the nozzle heads, wherein tips of all the nozzles are configured to be permitted to be simultaneously inserted into some of the wells in the micro plate, at least one of the row interval or the column interval of the nozzles is set to a natural number multiple of the row interval or the column interval of the corresponding wells, the natural number being two or more, and at least one of the row number or the column number of all the corresponding nozzles is one to the natural number of the row number or the column number of the wells. | 01-23-2014 |
20140045275 | APPARATUS FOR HERMETICALLY SEALED STORAGE OF LIQUIDS FOR A MICROFLUIDIC SYSTEM - An apparatus for hermetically sealed storage of liquids for a microfluidic system includes at least one cavity and at least one sealing cone through which a connection to the microfluidic system is configured to be established and which closes the cavity. | 02-13-2014 |
20140051182 | Pipetting Apparatus, Pipetting Container and Method for the Production Thereof - The invention relates to a pipetting apparatus for pipetting laboratory samples into a pipetting container which can be connected to the pipetting apparatus, which pipetting container is in particular designed according to the invention, comprising a container side and a first connection section, by means of which the pipetting container can be connected to the pipetting apparatus, and comprising an information carrying device with at least one information section, which carries information, on this container side; the pipetting apparatus comprising an electric information reading device, by means of which information contained on the information reading device can be read when the pipetting container is connected to the pipetting apparatus, and which comprises at least one electric sensor device, which comprises at least one sensor section, opposite to which a measuring space is formed, wherein the sensor device is configured to read the information content of at least one information section when the latter is arranged in the measuring space. The invention furthermore relates to the pipetting container or adapter element, which can be used with the pipetting apparatus, and a method for the production thereof. | 02-20-2014 |
20140080226 | FLUID TRANSPORT SYSTEM WITH GASKET - Fluid transport system, including methods and apparatus, for moving fluid. The system may include a plurality of wells each having a rim. The system also may include a gasket defining a plurality of apertures that extend through the gasket from a top side to a bottom side of the gasket. The bottom side may define a plurality of grooves, with each groove extending at least partway around an axis defined by an aperture of the plurality of apertures. The gasket may be configured to have the top side of the gasket engaged with a pump assembly and at least a portion of the rim of each of the wells disposed in at least one groove of the plurality of grooves, to provide sealed communication between the pump assembly and each of the wells. | 03-20-2014 |
20140087479 | LIQUID REAGENT STORAGE AND OPERATION OF ANALYTICAL DEVICES - Improved mechanisms for storing and introducing liquid volumes in a liquid handling device and, in particular, improved mechanisms for rupturing a liquid storage package to introduce liquid into the device, improvements to the stability of a liquid receiving chamber inside the device and improvements to liquid handling in the receiving chamber are achieved. | 03-27-2014 |
20140106467 | PIPETTING UNIT AND METHOD OF PIPETTING A TEST LIQUID - A pipetting unit and a method of using the pipetting unit for pipetting a volume V | 04-17-2014 |
20140134750 | TEST DEVICE AND METHODS OF USE - A test device for analyzing fluid samples. The test device includes a planar support member for supporting reagent pads, and a handle attached to, or for attaching to the planar support member. The test device can be treated with a fluid sample by disposing a fluid sample on the reagent pads. The fluid sample can be disposed onto the reagent pads by the handle, or by dipping the test device into the fluid sample. | 05-15-2014 |
20140162373 | MICROCHIP AND LIQUID SENDING METHOD FOR MICROCHIP - A microchip capable of sending liquid in a micro flow channel to a predetermined place irrespective of the pressure difference and sending a mixture of two or more liquid masses to a predetermined place even if the channel structure is simple. The microchip comprises an intermediate reservoir portion provided in a micro flow channel and adapted for temporarily holding liquid sent through the micro flow channel. The microchip is characterized in that the intermediate reservoir portion has a side channel, the volume of the intermediate reservoir portion is smaller than the total volume of the liquid sent into the intermediate reservoir portion, the side channel is provided for communication of a micro flow channel on the upstream side of the intermediate reservoir portion with a micro flow channel on the downstream side thereof, and the cross-section area of the side channel is smaller than that of the micro flow channel. | 06-12-2014 |
20140199779 | AUTOMATIC ANALYZER - An automatic analyzer is capable of controlling the gap between the tip of the sample nozzle and the bottom surface of the reaction container and restricting the sample attached to the tip of the sample nozzle. A movement distance of an arm is calculated and stored while the tip of the sample nozzle contacts a coordinate measurement stand until a stop position detector detects a stop position detection plate. The sample nozzle is moved toward the bottom surface of the reaction container and is stopped at the time when the stop position detector detects the stop position detection plate. The arm is moved upwardly for the movement distance stored in memory from this position. The sample nozzle can be stopped such that the tip of the sample nozzle is contacted to the bottom surface of the reaction container and the bend (warp) of the sample nozzle is restricted. | 07-17-2014 |
20140212986 | Passive Micro-vessel and Sensor - An electrically passive device and method for in-situ acoustic emission, and/or releasing, sampling and/or measuring of a fluid or various material(s) is provided. The device may provide a robust timing mechanism to release, sample and/or perform measurements on a predefined schedule, and, in various embodiments, emits an acoustic signal sequence(s) that may be used for triangulation of the device position within, for example, a hydrocarbon reservoir or a living body. | 07-31-2014 |
20140220702 | FLUID RETENTION PLATES AND ANALYSIS CARTRIDGES - Fluid storage containers and analysis cartridges for use in assay processes are presented. In addition, systems comprising such storage containers and analysis cartridges and methods of using such containers and cartridges are presented as well. In specific embodiments, fluid storage containers are configured to be coupled to analysis cartridges in a first stage and a second stage. | 08-07-2014 |
20140242719 | Pipette With Piston Rotation Lock - The present invention concerns a pipette comprising a mechanism with which the stroke length of a piston can be changed by rotating the piston rod. The pipette comprises a locking mechanism which prevents the rotation of the piston rod when the piston has been pushed a certain distance downwards from its upper position, but does not prevent the rotation when the piston is in its upper position. | 08-28-2014 |
20140273268 | PREPARATION OF SAMPLES FOR ANALYSIS - An apparatus for preparation of samples for analysis comprising includes structure ( | 09-18-2014 |
20140287523 | Linear Track Diagnostic Analyzer - A diagnostic analyzer system includes a linear track, at least one pipetting device, and at least one diagnostic module. The linear track includes a pre-treatment lane disposed parallel to at least one processing lane. The linear track moves reaction vessels, containing samples, held by the pre-treatment lane and by the at least one processing lane. The pre-treatment lane pre-treats the samples in the reaction vessels of the pre-treatment lane. The pre-treatment lane is not connected to any diagnostic module for testing the samples in the reaction vessels of the pre-treatment lane. The at least one pipetting device transfers the pre-treated samples from the reaction vessels in the pre-treatment lane to the reaction vessels in the at least one processing lane. The at least one diagnostic module is connected to the at least one processing lane for testing the pre-treated samples transferred into the reaction vessels in the at least one processing lane. | 09-25-2014 |
20140287524 | MICROFLUIDIC DEVICE AND CONTROL METHOD THEREOF - A microfluidic device and a control method, the microfluidic device including a platform including a chamber configured to accommodate a sample, a channel connected to the chamber, and a metering unit connected to the chamber by the channel and configured to meter an amount of the sample, wherein the metering unit includes a metering chamber configured to measure the amount of the sample, and an accommodation chamber connected to the metering chamber and configured to accommodate the sample to prevent the sample from overflowing out of the metering chamber. | 09-25-2014 |
20140287525 | Reagent Container Pack - A reagent container pack for storing, preserving, and automatically unsealing and resealing a plurality of reagent containers in a reagent container pack on-board an automated clinical sample analyzer for analyzing analytes in a body fluid. | 09-25-2014 |
20140295572 | MANIPULATION OF FLUIDS AND REACTIONS IN MICROFLUIDIC SYSTEMS - Microfluidic structures and methods for manipulating fluids and reactions are provided. Such structures and methods may involve positioning fluid samples, e.g., in the form of droplets, in a carrier fluid (e.g., an oil, which may be immiscible with the fluid sample) in predetermined regions in a microfluidic network. In some embodiments, positioning of the droplets can take place in the order in which they are introduced into the microfluidic network (e.g., sequentially) without significant physical contact between the droplets. Because of the little or no contact between the droplets, there may be little or no coalescence between the droplets. Accordingly, in some such embodiments, surfactants are not required in either the fluid sample or the carrier fluid to prevent coalescence of the droplets. Structures and methods described herein also enable droplets to be removed sequentially from the predetermined regions. | 10-02-2014 |
20140308750 | Fluid Transfer Appratus - The invention relates to a fluid transfer apparatus, in particular pipetting apparatus, for transferring at least one fluid laboratory sample, in particular a biochemical or medical laboratory sample, comprising a base body, which has a connecting section serving for connecting a container to the base body for the intake of the at least one fluid sample into the container, a movement device, which can bring about the intake and/or delivery of at least one fluid laboratory sample into the container, an electrical control device, which controls at least one function of the fluid transfer apparatus, a sensor device, which comprises at least one acceleration sensor which is signal-connected to the control device and by means of which at least one acceleration value can be measured during the movement of the fluid transfer apparatus, wherein the control device is designed such that it uses the at least one acceleration value during the control of the at least one function. The invention furthermore relates to a method for using at least one acceleration value in a fluid transfer apparatus. | 10-16-2014 |
20140329333 | MICRO-SAMPLING-SYSTEM FOR SMALL AMOUNTS OF FLUID SAMPLES FOR ANALYSIS IN THE VAPOUR PHASE - Microsampling system for small amounts of fluid samples for analysis in the vapour phase, which comprises a plurality of integrated functional units and is suitable for small sample quantities with fast reaction times. | 11-06-2014 |
20150031143 | SYSTEM FOR PRETREATING SAMPLE - A sample pretreatment system is equipped with a pipetting device for pipetting multiple primary samples to make multiple aliquot samples. The sample volume expected to be held in a test tube is set as a minimum guaranteed volume for each type of test tube; and a minimum guaranteed volume value is set for each type of the test tubes. A cumulative totaling unit adds up cumulatively the aliquot volumes of the aliquot samples based on pipetting request information with regard to the supplied test tubes. A reading unit reads the minimum guaranteed volume of the supplied test tube; and an aliquot sample preparation unit compares the minimum guaranteed volume successively with the cumulative total values of the aliquot volumes of the aliquot samples, and causes a pipetting device to pipette a maximum number of the aliquot samples in a manner not exceeding the minimum guaranteed volume. | 01-29-2015 |
20150037904 | INTERFACE DESIGNED WITH DIFFERENTIAL PUMPING AND BUILT-IN FIGURE OF MERIT METHOD TO MONITOR CHAMBERS WHERE ENVIRONMENTALLY SENSITIVE SAMPLES ARE PREPARED AND TRANSFERRED FOR ANALYSIS - In some embodiments, a system may function to transfer samples in a controlled environment. The system may include a sample container configured to convey a sample from a first device to a second device. The first device may be under pressure and the second device may be under vacuum. The second device may include a load chamber which functions to accept the sample from the sample container. The second device may include a pump chamber coupled to the load chamber using a conduit such that the pump chamber is in fluid communication with the load chamber as required. The second device may include a high vacuum pump coupled to the pump chamber. The second device may include a vacuum pump coupled to the pump chamber through the high vacuum pump in sequence. The second device may include an orifice sized to significantly restrict the flow of fluids through the conduit coupling the pump chamber to the load chamber, wherein the orifice is configured to allow for a transition from a viscous into a molecular flow. | 02-05-2015 |
20150056717 | Microfluidic Metering of Fluids - This document provides methods and devices for metering fluids. In some cases, the methods and devices include intersecting channels that include capillary-stop geometries at each intersection point that guides the fluids on a desired path, which is controlled by the opening and closing of valves. For example, a metering channel can intersect a loading channel and intersect an outflow channel and a metering portion can be defined by the geometry of the metering channel between the intersection points. | 02-26-2015 |
20150056718 | DUAL SYRINGE - A dual syringe is provided. The dual syringe includes a first barrel and a second barrel. The first barrel may slidably engage within the second barrel. A first chamber and a second chamber may be formed in the first barrel. A first plunger may be slidably engaged within the first chamber and a second plunger may be slidably engaged within the second chamber. A first valve may be attached in between the first chamber and a mixing chamber of the second barrel | 02-26-2015 |
20150087078 | WELL SEALS IN PIPETTE WORKSTATIONS - A pipette workstation of the type dispensing fluids into a microtiter plate with well closure structures that are thimble-shaped members with ridges that form a seal. The closure structures have a beveled nose lower end for self-centering entry into a well with a lower peripheral ridge acting as a first seal. An intermediate peripheral ridge contacts the wall of the well and forms a second seal barrier. An upper peripheral ridge has a diameter that barely enters the well for wedge action stoppage of entry of closure member into the well and further sealing the well. A pipette head with a nozzle array attaches to an array of seals and inserts the seals into wells. The pipette head uses a vacuum force to remove the seals. | 03-26-2015 |
20150093838 | MICROFLUIDIC VALVE SYSTEMS - A microfluidic device having a chip defining fluid channels and having toner patches printed within the channels. The toner patches are printed with hydrophobic toner to apply inertial pressure to fluids travelling through the channels. The density of hydrophobic toner and the dimensions of the toner patch can be varied to alter the inertial pressure applied to the fluid. The chip can be rotated about a rotational axis to apply external pressure to fluids sufficient to overcome the inertial pressure created by the toner patch to push fluid past the toner patch. The rotational speed of the chip can be varied to facilitate movement of fluid through the channels and to push fluid past the hydrophobic toner patches. | 04-02-2015 |
20150099310 | SAMPLE INTRODUCTION SYSTEM - A sample port system/device associated with a fluid collection device is provided and is configured to receive fluid-containing devices of varying diameters. A method of improving the work flow and safety involved in acquiring and/or testing fluid samples using such sample port system/device is also provided. | 04-09-2015 |
20150118761 | MANIPULATION OF FLUIDS AND REACTIONS IN MICROFLUIDIC SYSTEMS - Microfluidic structures and methods for manipulating fluids and reactions are provided. Such structures and methods may involve positioning fluid samples, e.g., in the form of droplets, in a carrier fluid (e.g., an oil, which may be immiscible with the fluid sample) in predetermined regions in a microfluidic network. In some embodiments, positioning of the droplets can take place in the order in which they are introduced into the microfluidic network (e.g., sequentially) without significant physical contact between the droplets. Because of the little or no contact between the droplets, there may be little or no coalescence between the droplets. Accordingly, in some such embodiments, surfactants are not required in either the fluid sample or the carrier fluid to prevent coalescence of the droplets. Structures and methods described herein also enable droplets to be removed sequentially from the predetermined regions. | 04-30-2015 |
20150147819 | INTERFACING APPARATUS BETWEEN A LABORATORY AUTOMATION SYSTEM AND A PLATFORM FOR HANDLING CONSUMABLES AND LIQUIDS IN THE FIELD OF MOLECULAR BIOLOGY - Apparatus for automatically filling wells of plates with biological material from a laboratory automation system for conveying biological samples or reactants contained in test tubes, and automatically routing said plates towards processing modules of said biological material. Said apparatus contains a platform interposed between said laboratory automation system and a handling system of consumable products, which includes a horizontal crosspiece whereon a first robot and a second robot are sliding mounted, the first robot being provided with gripping means of pipettes adapted to collect and release the biological material or the reactant, and a second robot being provided with gripping means of consumable products. | 05-28-2015 |
20150147820 | SYSTEM FOR MANAGING INVENTORY OF BULK LIQUIDS - A system for managing bulk liquids for an automated clinical analyzer. The system comprises (a) at least one local reservoir for storing a bulk liquid for impending use, (b) at least one container for holding a bulk liquid before the liquid is transferred to a local reservoir, and (c) a controller for monitoring the level of a bulk liquid in a local reservoir. The local reservoir for storing a bulk liquid for impending use can be a trough. The use of troughs for storing a reagent, a diluent, or some other treating agent for impending use enables an aspirating/dispensing device having a plurality of pipettes to aspirate and dispense the reagent,diluent, or other treating agent at a high rate of throughput. The controller can monitor the level of a liquid in (a) a local reservoir for storing a bulk liquid for imminent use and the level of liquid in a (b) container for holding a bulk liquid before the liquid is transferred to a local reservoir. In the laboratory automation system described herein, the container for holding a bulk liquid before the liquid is transferred to a local reservoir can be a bottle. Other desirable features in the system include, but are not limited to, pump(s), valves, liquid level sensors. | 05-28-2015 |
20150290643 | Sample Metering Device - A sample metering device for a liquid sample comprises at least one capillary passage ( | 10-15-2015 |
20150314283 | FLUIDIC SYSTEM WITH FLUIDIC STOP - An embodiment of the invention relates to a fluidic system ( | 11-05-2015 |
20150321192 | MICROFLUIDIC STRUCTURE, MICROFLUIDIC DEVICE HAVING THE SAME AND METHOD OF CONTROLLING THE MICROFLUIDIC DEVICE - A microfluidic structure in which a plurality of chambers arranged at different positions are connected in parallel and into which a fixed amount of fluid may be efficiently distributed without using a separate driving source, and a microfluidic device having the same. The microfluidic device includes a platform having a center of rotation and including at least one microfluidic structure. The microfluidic structure includes a sample supply chamber configured to accommodate a sample, a plurality of first chambers arranged in a circumferential direction of the platform at different distances from the center of rotation of the platform, and a plurality of siphon channels, each of the siphon channels being connected to a corresponding one of the first chambers. | 11-12-2015 |
20150360221 | Reagent Mixer and Fluid Control Devices - An apparatus for preparing a reagent solution includes an enclosure and a container disposed within the enclosure. The container defines an internal cavity having a compressible volume and defines a passage providing fluidic communication between the internal cavity and the exterior of the container. Optionally, a compressible member is disposed within the internal cavity. A reagent is disposed within the internal cavity. | 12-17-2015 |
20160001289 | SYSTEM AND METHOD FOR PERFORMING DROPLET INFLATION - The present invention generally pertains to a system for performing droplet inflation, and methods and kits comprising the same. The system comprises at least one microfluidic channel comprising one or more droplets flowing therein, one or more fluid reservoirs, one or more inflators, one or more inflator nozzles, and at least one mechanism for disrupting an interface between a droplet and a fluid. The present invention provides for the inflation of a relatively controlled volume of fluid into a droplet resulting in an increase in the volume of the droplet relative to its volume prior to inflation and, accordingly, dilution of the concentration of species, if any, previously present and emulsified in the droplet. | 01-07-2016 |
20160038938 | MICROFLUIDIC CHIP WITH SEALED ON-BOARD REAGENT - A microfluidic product pouch assembly may be used in a microfluidic chip. The microfluidic product pouch may include a pouch surrounding an inner chamber and having a rupturing portion and an inner membrane positioned within the inner chamber. The inner membrane may separate the inner chamber into a first cavity and a second cavity. A reagent may be positioned within the first cavity and/or the second cavity. The microfluidic product pouch assembly may also include a rupturing structure. The rupturing structure may be configured to selectively break the rupturing portion of the microfluidic product pouch. | 02-11-2016 |
20160038941 | MICROFLUIDIC CIRCUIT ELEMENT COMPRISING MICROFLUIDIC CHANNEL WITH NANO INTERSTICES AND FABRICATION METHOD THEREOF - A microfluidic circuit element comprising a microfluidic main channel and nano interstices is disclosed. The nano interstices are formed at both sides of the main channel and are in fluid communication with the main channel. The nano interstices have a height less than that of the main channel, gives more driving force of the microfluidic channel and provides stable flow of a fluid. The microfluidic circuit element may be made from a plastic material having a contact angle of 90 degrees or less. The microfluidic circuit element is particularly useful when filling a liquid sample to the channel which is empty or filled with air and shows greatly improved a storage stability. | 02-11-2016 |
20160077118 | AUTOMATED SAMPLE HANDLING INSTRUMENTATION, SYSTEMS, PROCESSES, AND METHODS - The present invention provides a processing station for automatically processing a biological sample, a system for automated real-time inventory control of consumables within a biological sample handling or assay instrument, a high throughput random access automated instrument for processing biological samples, an automated instrument for processing or analysis of a sample, and processes for automated mucoid detection and elimination. Methods of using the disclosed instruments, mucoid detection processes, and systems to process and/or analyze samples are also disclosed. | 03-17-2016 |
20160114324 | FLUID HANDLING DEVICE AND METHOD OF HANDLING FLUID - A fluid handling device has a first substrate, a second substrate, and a resin film disposed between the first substrate and the second substrate. The first substrate includes a first channel, a valve body facing area having a substantially circular segment-shaped opening, a second channel, and a partition wall formed between the valve body facing area and an end on one side of the second channel. The second substrate includes a pressure chamber. The resin film includes a substantially spherical cap-shaped diaphragm portion. A radius of an outer edge of the diaphragm portion is smaller than a radius of a circular arc of the valve body facing area. The diaphragm portion is so arranged as to straddle the valve body facing area and the end on one side of the second channel. | 04-28-2016 |
20160144363 | GAS-BASED MICROFLUIDIC DEVICES AND OPERATING METHODS THEREOF - Gas-based microfluidic devices and operating methods of gas-based microfluidic devices are provided. The gas-based microfluidic devices comprise a drive module and a microfluidic platform, in which the microfluidic platform further comprises a microfluidic element having an injection chamber, a process chamber, an air chamber, an overflow channel, a barrier, and at least one detection chamber. Gases in the air chamber enable solutions to move toward the direction opposite to the centrifugal force applied by the drive module. Accordingly, the operating methods utilize the gases compressed in the air chamber to move solutions to difference components in the microfluidic element. | 05-26-2016 |
20160158743 | DEVICES AND METHODS FOR MANIPULATING DEFORMABLE FLUID VESSELS - A fluid container comprises a first vessel, a second vessel connected or connectable to the first vessel, and a sealing partition preventing fluid flow from the second vessel. The container further includes a spherical opening element initially supported within the second vessel by the sealing partition and configured to be contacted with the sealing partition to open the sealing partition and permit fluid flow from the second vessel | 06-09-2016 |
20160175835 | FLUIDIC CARTRIDGE AND METHOD FOR PROCESSING A LIQUID SAMPLE | 06-23-2016 |
20160187239 | Assay cartridge processing systems and methods and associated assay cartridges - An assay cartridge processing system includes an agitation source for agitating assay components within an assay cartridge, and a timing module for controlling timing of agitation. An assay cartridge processing method includes applying agitation to an assay cartridge to mix assay components, and electronically controlling timing of agitation. An assay cartridge processing system includes a puncture device for puncturing an assay cartridge to allow fluid flow, and a timing module for controlling timing of puncturing. An assay cartridge processing method includes puncturing a vent of a capillary channel of an assay cartridge to allow fluid flow from an inlet port of the assay cartridge into the capillary channel, and electronically controlling timing of the step of puncturing. An assay cartridge includes a capillary channel, an inlet port, and a vent including a frangible seal for preventing fluid flow from into the capillary channel when the frangible seal is intact. | 06-30-2016 |
20160202280 | Methods and Systems for Automated Pipette Tracking | 07-14-2016 |
20180021776 | VOLTAGE UPCONVERTER | 01-25-2018 |