Class / Patent application number | Description | Number of patent applications / Date published |
436096000 | Hetero-N | 42 |
20080311671 | Mass Spectrometry Method for Measuring Vitamin B6 in Body Fluid - Provided are methods of detecting the presence or amount of the active form of vitamin B6, pyridoxal 5′-phosphate, in a body fluid sample using tandem mass spectrometry coupled with liquid chromatography. | 12-18-2008 |
20080318331 | Anthraquinone Derivatives as Markers For Liquids - The use of compounds of the general formula (I) | 12-25-2008 |
20100120160 | Fluorescent Probe - A compound represented by the formula (I) wherein R | 05-13-2010 |
20100129921 | MONITORING OF IONIC LIQUID CATALYST DEACTIVATION - A process for determining ionic liquid catalyst deactivation including (a) collecting at least one sample of an ionic liquid catalyst; (b) hydrolyzing the at least one sample to provide at least one hydrolyzed sample; (c) titrating the at least one hydrolyzed sample with a basic reagent to determine a volume of the basic reagent necessary to neutralize a Lewis acid species of the ionic liquid catalyst; and (d) calculating the acid content of the at least one sample from the volume of basic reagent determined in step (c) is described. Processes incorporating such a process for determining ionic liquid catalyst deactivation are also described. These processes are an alkylation process, a process for controlling ionic liquid catalyst activity in a reaction producing by-product conjunct polymers, and a continuous process for maintaining the acid content of an ionic liquid catalyst at a target acid content in a reaction producing by-product conjunct polymers. | 05-27-2010 |
20100129922 | DEVICES AND METHODS FOR THE COLLECTION AND DETECTION OF SUBSTANCES - The present invention provides a single self-contained device for collecting, extracting, on-site testing, and transferring for forensic confirmatory analysis, a wide variety of substances including, but not limited to, drugs of abuse, explosives, weapons of mass destruction, food toxins and industrial wastes. Samples can be obtained from a surface by swabbing a suspect area or the testing of solid materials (pills, capsules, powders), air samples and biological and non-biological fluids by placing the substance in the device. The device includes a swab, a retention well including a wash, and analysis technologies that can be, for example, a lateral flow testing system. The swab is rinsed with a wash prior to testing thereby not compromising the chemistry of the detection technologies and allowing for a wide variety of applications under a number of field conditions. Also, the device is a single self-contained unit instead of having a separate reagent droppers or sprays, making it compact and easy to use. Moreover, the device is designed to not only collect and test samples but to seal the originally target analyte, not affected by testing procedures, in a specially designed cap for shipping under chain of custody documentation to a forensic laboratory for confirmatory testing. | 05-27-2010 |
20110086429 | METHODS AND DEVICES FOR DETECTING OZONE AND CARBONYL-CONTAINING COMPOUNDS - Methods and devices are provided for detecting the presence of both ozone and carbonyl-containing compounds in air samples. Method and device for detecting the presence of ozone and carbonyl-containing compounds in an air sample, the method comprising: (a) contacting an air sample with an ozone-reactive adsorbent wherein if ozone is present in the air sample, the ozone reacts with the ozone-reactive adsorbent to form an aldehyde product; (b) contacting the air sample from Step (a) further with a carbonyl-reactive adsorbent wherein if a carbonyl-containing compound is present in the air sample, the carbonyl-containing compound reacts with the carbonyl-reactive adsorbent to form a first hydrazone product; (c) eluting with a solvent from the carbonyl-reactive adsorbent into the ozone-reactive adsorbent, wherein any aldehyde product of step (a) forms a second hydrazone product; and (d) analyzing eluate from Step (c) for presence of hydrazone products formed in Step (b) and Step (c). | 04-14-2011 |
20110312100 | ASSAY METHOD FOR DETECTING PRIMARY AMINES - The invention provides an assay method for the detection of a primary amine analyte in an aqueous body fluid, which method comprises contacting a sample of said body fluid at a pH below 9.5 with a thiol and an unsaturated cis-dialdehyde and testing for the presence of a pyrrole reaction product. | 12-22-2011 |
20120295363 | MATERIAL AND METHOD FOR TRAPPING, DETECTING AND QUANTIFYING HETEROCYCLIC AROMATIC COMPOUNDS AND OTHERS - What is provided includes a porous sol-gel material whose intrinsic pH is lower than 1 and comprising at least one probe molecule chosen from the group consisting of croconic acid, p-dimethyl-aminobenzaldehyde (DMABA), p-dimethyl aminocinnamaldehyde (DMACA), p-methoxybenzaldehyde (MOB) and 4-methoxy-1-naphtaldehyde (MON). In addition, a detection system containing the porous sol-gel material and a method of preparation and use of the porous sol-gel material for trapping and/or detecting and optionally quantifying at least one chemical compound such as indole and indole compounds are provided. | 11-22-2012 |
20130017616 | Methods For Treating Inflammation - The present invention provides methods for treating or limiting development of inflammatory disorders. | 01-17-2013 |
20130071939 | URINE ANALYSIS METHOD, DEVICE THEREOF, PROGRAM USED IN URINE ANALYSIS METHOD, AND STORAGE MEDIUM THEREOF - An analysis device includes determination means, capable of performing a first determination on whether a specific component in urine is positive or negative, on the basis of a color reaction between a reagent and the specific component in urine; and optical measurement means capable of working out data on light absorption characteristics of the urine itself with respect to light of a predefined wavelength region. When the data on the light absorption characteristics lies within a predefined range, and a result of the first determination is either positive or negative as established beforehand, the determination means changes the result of the first determination to a false positive or a false negative, or performs second determination to the effect that there is a likelihood of a false positive or a false negative. | 03-21-2013 |
20130130396 | Detection of Nicotine Metabolites - The present invention relates to assays for detection of nicotine metabolites, in particular cotinine, in fluid samples and uses of these assays in quantification of smoking habits. The assays comprise contacting a body fluid sample with a cyanogen halide and a pyrazolone compound and detecting a change in light absorbance of the pyrazolone compound which is associated with the presence of nicotine metabolites. Also provided are assay kits including a cyanogen halide or cyanogen halide-precursor(s) and a pyrazolone compound. | 05-23-2013 |
20140220698 | METHOD FOR RAPIDLY MEASURING MELATONIN ADULTERATION OF CHINESE PATENT MEDICINE OR HEALTHCARE FOOD - A method for rapidly measuring melatonin adulteration of Chinese patent medicines and healthcare foods comprises: (1) extracting melatonin added to a Chinese patent medicine or healthcare food by using ethyl acetate; and (2) adding p-dimethylaminocinnamaldehyde to the extracted solution, and observing color. The method is rapid, simple and convenient, has strong specificity, high accuracy, reaction sensitivity, and a wide application range, and is applicable to on-site detection of melatonin adulteration of a Chinese patent medicine or healthcare food. | 08-07-2014 |
20150132857 | Systems, Sensing Devices And Methods For Detection Of Airborne Contaminants - A device for detecting airborne contaminants includes a protonated, electrically conductive sensing material with affinity for binding with, and capable of being deprotonated by, the airborne contaminant. Electronics measure a property of the sensing material that is sensitive to deprotonation and generates signals indicative of the airborne contaminant. A method for detecting airborne contaminants includes: determining a property change of the protonated, electrically conductive material; and determining presence of the airborne contaminant based on the change. A system for detecting airborne contaminants includes: a data center in remote communication with multiple sensing devices each having: protonated, electrically conductive sensing material with affinity for binding with, and capable of being depronated by, an airborne contaminant, and electronics for relaying signals indicative of a sensing material deprotonation property to the data center; and wherein a user associated with a sensing device is notified of an abnormal level of the airborne contaminant. | 05-14-2015 |
20150377751 | METHOD OF COLLECTING AND QUANTIFYING MELANIN IN SKIN - A non-invasive method of obtaining a melanin derivative from a test subject. The method includes contacting a target skin surface with an adhesive to provide a sample of biological material and obtaining the melanin derivative from the sample of biological material. | 12-31-2015 |
20160069915 | MODULATORS OF PHARMACOKINETIC PROPERTIES OF THERAPEUTICS - The present application provides for a compound of Formula IV, | 03-10-2016 |
20160097721 | HANDHELD FLUOROMETER - A method of detecting concentration of dipicolinic acid and terbium chloride in a chemical composition with a fluorometer, wherein the fluorometer comprises an excitation source for emitting electromagnetic radiation at one or more wavelengths, and a detector module for detecting fluorescence emitted by dipicolinic acid, emitting electromagnetic radiation from the excitation source at wavelengths that induce fluorescence in dipicolinic acid-terbium chloride combination present in the chemical composition, detecting the fluorescence emitted by the dipicolinic acid-terbium chloride combination via the detector module, and determining the concentration of dipicolinic acid using predetermined relationship between fluorescence emitted and the concentration of dipicolinic acid-terbium chloride combination. | 04-07-2016 |
20160131641 | COMPOUNDS AND COMPOSITIONS FOR USE AS ALKYLATING AGENT SENSORS AND METHODS OF USE THEREOF - This invention provides compound having a structure of Formula I: | 05-12-2016 |
436097000 | Bile pigment | 2 |
20150369827 | REDUCTION OF FALSE POSITIVE ON REAGENT TEST DEVICES - Methods and systems are disclosed including a reagent analyzer, comprising a test analyzing mechanism, such as an optical imaging system, configured to read a first sample of a specimen combined with a reagent configured to react with the sample in a presence of an analyte of interest and a second sample of the specimen that is not combined with a reagent, and to output one or more first signals indicative of the test analyzing mechanism reading the first and second samples; and a processor receiving the one or more first signals and executing logic to analyze the second sample responsive to the processor determining that the analyte of interest is present in the first sample. The processor may execute logic to analyze the second specimen utilizing one or more ratio algorithm and comparing the results of the algorithm against predetermined values indicative of expected color. | 12-24-2015 |
20160169917 | WATER SOLUBLE POLYFLUORENE FUNCTIONALIZED WITH GLUCURONIC ACID USEFUL IN BILIRUBIN SENSING | 06-16-2016 |
436098000 | Plural nitrogen in the same ring (e.g., barbituates, creatinine, etc.) | 23 |
20090311795 | BILATERAL CONTROL OF FUNCTIONS TRADITIONALLY REGULATED BY ONLY SEROTONIN OR ONLY DOPAMINE - Methods of using amino acid precursors of the serotonin and catecholamine neurotransmitter systems and laboratory urinary assay of serotonin and catecholamine neurotransmitter levels for optimal treatment of transporters for neurotransmitters, and or neurotransmitter dysfunction and dysfunction of systems regulated or controlled by the serotonin and/or catecholamine neurotransmitter systems. The methods may also include determining a urinary neurotransmitter phase response to a change in dosing of supplemental amino acid precursors of the serotonin and catecholamine neurotransmitters to optimally treat neurotransmitter transporters, neurotransmitter dysfunction and dysfunction of systems regulated or controlled by the serotonin and/or catecholamine neurotransmitter systems. | 12-17-2009 |
20100035354 | PROCESS FOR PREPARING AZACYTIDINE INTERMEDIATE - The present invention provides a processes for preparing 5-Azacytidine, and intermediates thereof. The present invention further provides an analytical method for determining the purity of 5-Azacytidine in a sample. | 02-11-2010 |
20100047916 | DETECTION OF MATERIALS VIA NITROGEN OXIDE - Methods and devices for detecting the presence of a NO forming material (e.g., a material that can form, or is, a nitrogen monoxide molecule) are disclosed based on detection of fluorescence exhibited by NO molecules in a first vibrationally excited state of a ground electronic state. Such excited NO molecules can be formed, for example, when small amounts of explosives are photodissociated. By inducing fluorescence of the material, a distinct signature of the explosive can be detected. Such techniques can be performed quickly and with a significant standoff distance, which can add to the invention's utility. In another aspection of the invention, methods and apparatus for generating electromagnetic radiation are disclosed. Such methods and apparatus can be used in conjunction with any detection method disclosed herein. | 02-25-2010 |
20100178705 | Apparatus, System And Method For Consumer Detection Of Contaminants In Food Stuffs - An apparatus, system and method of detecting contaminants, such as melamine, in at least one ingestible item. The apparatus, system and method may include a disposable notched probe having therein at least one send and one receive fiber optic, or electrical, or heat source, and a reactant associated with said disposable notched probe, wherein a reaction of the reactant with at least a portion of the ingestible item indicates, to the consumer user, a presence of a contaminant. | 07-15-2010 |
20110003395 | SPECIFIC ANALYSIS OF ANALYTES USING REAGENT COMPOUNDS, LABELING STRATEGIES, AND MASS SPECTROMETRY WORKFLOW - Labeling reagents, sets of labeling reagents, and labeling techniques are provided for the relative quantitation, absolute quantitation, or both, of ketone or aldehyde compounds including, but not limited to, analytes comprising steroids or ketosteroids. The analytes can be medical or pharmaceutical compounds in biological samples. Methods for labeling, analyzing, and quantifying ketone or aldehyde compounds are also disclosed as are methods that also use mass spectrometry. | 01-06-2011 |
20110151572 | METHOD, DEVICE AND APPARATUS FOR MEASURING THE CONCENTRATION OF CREATININE, AND METHOD, DEVICE AND APPARATUS FOR MEASURING THE AMOUNT OF SALT IN URINE USING THE SAME - A method for measuring the concentration of creatinine includes the steps of: (A) mixing a sample containing creatinine with a creatinine quantitative reagent including 1-methoxy-5-methylphenazinium in the absence of picric acid and any enzyme responsive to creatinine, to cause the creatinine to reduce the 1-methoxy-5-methylphenazinium; (B) electrochemically or optically measuring the amount of the 1-methoxy-5-methylphenazinium reduced in the step (A); and (C) determining the concentration of the creatinine contained in the sample from the amount of the reduced 1-methoxy-5-methylphenazinium measured in the step (B). | 06-23-2011 |
20110207231 | Melamine Assay Methods and Systems - A method of detecting melamine which includes providing a quantity of SERS-active particles and mixing the SERS-active particles with a solution containing melamine. The method further includes detecting a surface enhanced Raman spectrum of the melamine. The foregoing method may optionally include aggregating the SERS-active particles. Aggregation may occur before or after the SERS-active particles are mixed with a solution containing melamine. The method of detecting melamine may optionally include concentration of the SERS-active particles. The method may further include mixing a chaotropic agent having a higher affinity for a selected binding site than melamine into the solution containing melamine. The method may further include mixing a quantity of a SERS-active standard having a known SERS spectrum with the solution containing melamine and SERS-active particles. Assay apparatus and systems are also disclosed. | 08-25-2011 |
20120196378 | Methods, Mixtures, Kits and Compositions Pertaining to Analyte Determination - This invention pertains to methods, mixtures, kits and compositions pertaining to analyte determination by mass spectrometry using labeling reagents that comprise a nucleophilic reactive group that reacts with a functional group of an analyte to produce a labeled analyte. The labeling reagents can be used as isobaric sets, mass differential labeling sets or in a combination of isobaric and mass differential labeling sets. | 08-02-2012 |
20120264222 | Method and Device for Detection of Nitroamines - An ultrasensitive method for detecting non-aromatic non-planar nitroamine analytes in a sample is provided. | 10-18-2012 |
20120264223 | METHODS FOR DETECTING SULFHYDRYL-CONTAINING COMPOUNDS IN A BIOLOGICAL TEST SAMPLE - The invention relates to methods for detecting the presence of a compound of formula I in a biological test sample: | 10-18-2012 |
20130065318 | DETECTION OF ANALYTES INCLUDING NITRO-CONTAINING ANALYTES - Sensors and methods for determination of analytes are provided. Analytes including explosives (e.g., RDX or PETN) may be determined by monitoring, for example, a change in an optical signal of a material upon exposure to the analyte. In some embodiments, the analyte and the material may interact via a chemical reaction to form a new emissive species. Embodiments described herein may provide inexpensive sensors with high selectivity and sensitivity. | 03-14-2013 |
20130071940 | METHODS OF CHEMOSELECTIVE DERIVATION OF MULTIPLE CLASSES OF METABOLITES - Chemoselective derivatization of biological amines, carboxylic acids, aldehydes or ketones are employed in methods to detect a plurality of components, or members of a component, such as metabolites, that vary in molecular structure. The methods of the invention can be employed in aqueous and nonaqueous conditions. | 03-21-2013 |
20130084644 | THIN-FILM TRANSISTORS FOR CHEMICAL SENSOR APPLICATIONS - A chemical sensor is disclosed. The chemical sensor is an electronic device including in specific embodiments a first transistor and a second transistor. The first transistor includes a semiconducting layer made of a first semiconductor and carbon nanotubes. The second transistor includes a semiconducting layer made of a second semiconductor, and does not contain carbon nanotubes. The two transistors vary in their response to chemical compounds, and the differing response can be used to determine the identity of certain chemical compounds. The chemical sensor can be useful as a disposable sensor for explosive compounds such as trinitrotoluene (TNT). The electronic device is used in conjunction with an analyzer that processes information generated by the electronic device. | 04-04-2013 |
20130210159 | METHOD FOR DETERMINING ODOR WHEN USING A SELF-TANNING AGENT - A method for evaluating an odor generated when using a self-tanning agent, wherein at least one compound selected from pyrazine compounds represented by the following general formula (1) is used as an indicator substance: | 08-15-2013 |
20140024127 | METHODS FOR RECOVERING AND ANALYZING AMINES - The objects of embodiments in the present disclosure are to provide a method capable of recovering two or more amine compounds at the same time from a gas or solution, and also to provide a method capable of analyzing the recovered amines. | 01-23-2014 |
20140113379 | Apparatus, System and Method for Consumer Detection of Contaminants in Food Stuffs - An apparatus, system and method of detecting contaminants, such as melamine, in at least one ingestible item. The apparatus, system and method may include a disposable notched probe having therein at least one send and one receive fiber optic, or electrical, or heat source, and a reactant associated with said disposable notched probe, wherein a reaction of the reactant with at least a portion of the ingestible item indicates, to the consumer user, a presence of a contaminant. | 04-24-2014 |
20140127822 | Electro-Mechanical Switches and Methods of Use Thereof - One aspect of the invention relates to an ultrathin micro-electromechanical chemical sensing device which uses swelling or straining of a reactive organic material for sensing. In certain embodiments, the device comprises a contact on-off switch chemical sensor. For example, the device can comprises a small gap separating two electrodes, wherein the gap can be closed as a result of the swelling or stressing of an organic polymer coating on one or both sides of the gap. In certain embodiments, the swelling or stressing is due to the organic polymer reacting with a target analyte. | 05-08-2014 |
20140242711 | VITAMIN B2 DETECTION BY MASS SPECTROMETRY - Methods are described for measuring the amount of a vitamin B2 in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying vitamin B2 in a sample utilizing on-line extraction methods coupled with tandem mass spectrometric techniques. | 08-28-2014 |
20150056711 | Explosive Detection Polymer Comprising Functionalized Polyamine Polymers and Methods of Using the Same - Explosives detection polymers are provided that include a polyamine polymer, such as polyethylenimine, functionalized with a small molecule fluorophore. Methods for detecting an explosive material using polyamine polymers functionalized with a small molecule fluorophore are also provided. Sensors for explosive detection are provided that include a polyamine polymer functionalized with a small molecule fluorophore and a complementary analytical device. | 02-26-2015 |
20150330961 | METHOD FOR DETECTING ORGANIC AND INORGANIC EXPLOSIVES - Methods, devices, and systems are disclosed for releasing a sample from a carrier medium. A method of releasing a sample from a carrier medium comprises treating a sample on a carrier medium with a first organic reagent, wherein when the sample contains at least one inorganic salt, the first organic reagent binds to a cation of the inorganic salt to produce both a first volatile compound and an isolated anion of the inorganic salt; treating the sample on the carrier medium with a second organic reagent, wherein the second organic reagent reacts with the isolated anion to produce a second volatile compound; and releasing the treated sample from the carrier medium, wherein when the first and the second volatile compounds are produced, the releasing step releases at least one of the first and second volatile compounds from the carrier medium. | 11-19-2015 |
20160002421 | CROSS-LINKED POLYMER NETWORKS AND METHODS OF MAKING AND USING SAME - Cross-linked polymer networks that are at least partially conjugated (e.g., phenylene vinylene polymer networks). The cross-linked polymer networks may be thin-films disposed on a substrate. The cross-linked polymer network may be covalently bonded to the substrate. The cross-linked polymer networks can be used, for example, in methods of detecting explosives (e.g., RDX (cyclotrimethylenetrinitramine)) and degradation products thereof. | 01-07-2016 |
20160084769 | Fluorescent Caffeine Sensor And Portable Kit And Microfluidics Device For Caffeine Detection - The present invention relates to Caffeine Orange, a novel aqueous-phase fluorescence turn-on sensor for caffeine that is structurally based on a BODIPY-scaffold. The present invention further provides for methods of detecting and measuring caffeine in aqueous media. A change in the intensity or visible color of the fluorescence is detectable by either a fluorimeter or by the naked eye. The methods disclosed herein provide for the utilization of a reverse-phase SPE column, optionally as a component in a syringe or a microfluidics-based automation detection system. The invention further provides for the solid phase extraction of an analyte such as caffeine from a liquid medium, the extraction occurring on a microfluidic disc. | 03-24-2016 |
20160154001 | NEAR-INFRARED FLUORESCENT DYES WITH LARGE STOKES SHIFTS | 06-02-2016 |