Class / Patent application number | Description | Number of patent applications / Date published |
435287900 | Including a coated reagent or sample layer | 49 |
20080233636 | Humidity-controlled gas-borne matter collection device - A system includes a device for collecting gas-borne matter therein and a humectant provided external to the device for maintaining a desired humidity level for collected matter in the device. | 09-25-2008 |
20080241913 | CHROMATOGRAPHIC TEST DEVICE AND METHOD FOR DETECTING ANALYTE - The present invention provides a chromatographic test device, comprising a first blood cell separation member, a second blood cell separation member and a chromatographic carrier disposed in this order from the upstream side of the direction of development of a sample, wherein the first blood cell separation member is constituted so as to separate the blood cell components and the liquid components from each other based on a development speed; the second blood cell separation member is constituted so as to separate the blood cell components and the liquid components from each other based on filtration; and the chromatographic carrier carries a capturing substance being capable of binding specifically to the analyte. A method for detecting the analyte in the sample containing red blood cells and liquid components by using the chromatographic test device is also disclosed. | 10-02-2008 |
20080261297 | Assay Device - An assay device ( | 10-23-2008 |
20080274540 | BLOOD TESTING BOTTOMED TUBE, STOPPER FOR BLOOD TESTING BOTTOMED TUBE AND BLOOD TESTING CONTAINER - The present invention relates to a blood testing bottomed tube, which comprises a tubular member having an open one end and closed another end, and a coating layer formed on at least a part to be contacted with blood on said tubular member, said coating layer being made of a polyoxyalkylene alkyl ether or a polyoxyalkylene glycol ether, the present invention also relates to a stopper for a blood testing bottom tube and a blood testing container. | 11-06-2008 |
20090023202 | NUCLEIC ACID ANALYSIS DEVICE AND NUCLEIC ACID ANALYZER USING THE SAME - The present invention relates to a nucleic acid analysis device for analysis of nucleic acid in a sample through fluorometry, in which a localized surface plasmon by light irradiation, and in which a nucleic acid probe or a nucleic acid synthase for the analysis of the nucleic acid in the sample is disposed in a region of generation of the surface plasmon. The present invention allows the fluorescence intensifying effect of the surface plasmon to be produced efficiently and also enables the immobilization of a DNA probe or the nucleic acid synthase in a region on which the fluorescence intensifying effect is exerted, thus making it possible to carry out a measurement on the base elongation reaction without having to remove the unreacted substrate with the fluorescent molecule. | 01-22-2009 |
20090061506 | Method for precipitating mono and multiple layers of organophosphoric and organophosphonic acids and the salts thereof in addition to use thereof - The invention relates to a method for precipitating mono or multiple layers of organophosphoric acids of the general formula I (A) | 03-05-2009 |
20090075361 | Microfluidic Device and Method of Manufacturing the Microfluidic Device - A microfluidic device having a substrate with an array of curvilinear cavities. The substrate of the microfluidic device is preferably fabricated of a polymer such as polydimethylsiloxane (PDMS). The microfluidic device is manufactured using a gas expansion molding (GEM) technique. | 03-19-2009 |
20090111171 | LATERAL FLOW IMMUNOASSAY CONTROLS - Rapid lateral flow immunoassays have an extensive history of use in both the clinical and home settings. These devices are used to test for a variety of analytes, such as drugs of abuse, hormones, proteins, urine or plasma components and the like. The present invention provides an improved procedural control that indicates to the test user that at least a portion of the applied sample has passed through the test result zone of the test strip, and optionally that the test is complete and the test results may be read. | 04-30-2009 |
20100028987 | METHOD FOR IMPROVING HEAT STABILITY OF COMPOSITION CONTAINING WATER-SOLUBLE COENZYME-BOUND GLUCOSE DEHYDROGENASE (GDH) - The invention relates to a method for improving the heat stability of glucose dehydrogenase (GDH). The invention provides a method for preparing a glucose sensor with soluble flavin-bound GDH by providing a composition comprising soluble flavin-bound GDH at an acidic pH and heat drying the composition onto a glucose sensor. | 02-04-2010 |
20100041128 | Microfluidic Device for Application of Shear Stress and Tensile Strain - The present invention provides a cell culture device for applying shear stress and strain on single cells. The device includes at least one channel, at least one cell culture chamber having at least one single-cell attachment surface, a flexible membrane, at least one vacuum channel, and an inlet and an outlet. The inventive single-cell culture assembly fluid flow for applying fluid induced stress and/or substrate induced stress to cultured cells. | 02-18-2010 |
20100112680 | INDICATOR SYSTEM FOR DETERMINING ANALYTE CONCENTRATION - A method for quantitatively sensing, using an indicator system based on diffusion in space and time of a reaction front, for determining and reporting the prevailing concentration or exposure history of an analyte in food, beverage, and pharmaceutical monitoring for the state of quality, for ripeness indication in fruit, for monitoring environments for concentrations of sanitisers, pollutants and nutrients, for monitoring the residual life of filters, and for monitoring stream flows. | 05-06-2010 |
20100203623 | SUBSTRATE IMPRINTED UNIVERSAL SENSORS AND SENSORS HAVING NANO-TUNNELING EFFECT - A universal sensor fabrication approach, molecular substrate imprinting technique, which utilizes the interaction between molecular building blocks and the surface of a transducer to develop specific molecular recognition cavities has been established. Integration of molecular recognition cavities with the surface of a nanoscale transducer will result in a nano-tunneling effect that takes place which will provide a sensor or a device that exhibits new properties not already exhibited by either the molecular recognition cavities on a bulk transducer or the nanotransducer material. One of the new properties of this nano-tunneling effect is that a universal potentiometric molecular sensor can be fabricated and used to detect any compounds, whether they are ions or molecules, with enhanced selectivity, sensitivity, and stability when molecular recognition cavities or elements are integrated on the surface of a nanoscale transducer. | 08-12-2010 |
20100255567 | AUTO-CALIBRATING TEST SENSOR AND METHOD OF MAKING THE SAME - An electrochemical test sensor ( | 10-07-2010 |
20100291670 | Method for Detecting Candida on Skin - A method and system for rapidly detecting | 11-18-2010 |
20100323433 | HINGED CAP FOR DIAGNOSTIC DEVICE - A hinged cap for engaging a housing of a diagnostic device comprises a central body; two arms extending from opposing sides of one end of said central body, said arms being substantially parallel; each of said arms comprising a cap hinge member for engaging a housing hinge member on said housing, wherein said cap hinge member and said housing hinge member define a hinge axis around which said cap is pivotable between an open and a closed position with respect to said housing. | 12-23-2010 |
20100330662 | Apparatus, System and Method for Consumer Detection of Contaminants in Food Stuffs - An apparatus, system and method of detecting contaminants, such as salmonella, in at least one ingestible item. The apparatus, system and method may include a disposable detector having therein at least one circuit layer, wherein a reaction of the reactant with at least a portion of the at least one circuit layer indicates, to the consumer user, a presence of a contaminant. | 12-30-2010 |
20110111488 | BIOSENSOR - Disclosed herein is a biosensor, in which sensing electrodes are formed on an upper insulating substrate and a lower insulating substrate such that, using the sensing electrodes, a measuring device can determine whether a sample (e.g., blood) injected through a sample injection port is completely filled in a sample path and determine a time point at which the sample is injected and a time point at which the sample is completely filled. Therefore, it is possible to estimate the flow characteristics of the sample and the flow rate and use the estimated values to correct the measurement result, thus obtaining a more accurate measurement result. | 05-12-2011 |
20110294202 | BIOREACTORS WITH MULTIPLE CHAMBERS - A bioreactor for cultivating living cells in a liquid medium. In one embodiment of the present invention, the bioreactor has a first substrate having a first surface and an opposite second surface, defining a chamber therebetween for receiving the cells and the liquid medium. The bioreactor further has a barrier dividing the chamber into a first subchamber and a second subchamber, wherein the barrier has a porosity to allow the first subchamber and the second subchamber in fluid communication and allow at least one predetermined type of cells to permeate between the first subchamber and the second subchamber. | 12-01-2011 |
20120021502 | SENSOR FOR FAST DETECTION OF E-COLI - A method of fabricating biochip sensor comprising providing a precursor; depositing the precursor on a substrate to form a coating; and rapid melting/quenching treatment of the coating with an energy source to form micro/nanotextured surface with enhanced reflectance for fast chemiluminescence response of | 01-26-2012 |
20120231533 | DEVICE AND METHOD FOR THE STUDY OF CELL AND TISSUE FUNCTION - A chamber device for analyzing living cell(s). The chamber device includes a base and a lid that when reversibly pressed closed create a chamber. The base is configured with an optically transparent well to contain at least one cell. The lid has a breadth greater than the base and is configured to contain at least one sensor. The lid is further configured with a lip that when pressed between the lid and the base creates an impermeable seal. The base and the lid are configured so that, when closed and in use, the sensor remains spatially apart from the at least one cell. | 09-13-2012 |
20120301953 | GRAPHENE NANOMESH AND METHOD OF MAKING THE SAME - A graphene nanomesh includes a sheet of graphene having a plurality of periodically arranged apertures, wherein the plurality of apertures have a substantially uniform periodicity and substantially uniform neck width. The graphene nanomesh can open up a large band gap in a sheet of graphene to create a semiconducting thin film. The periodicity and neck width of the apertures formed in the graphene nanomesh may be tuned to alter the electrical properties of the graphene nanomesh. The graphene nanomesh is prepared with block copolymer lithography. Graphene nanomesh field-effect transistors (FETs) can support currents nearly 100 times greater than individual graphene nanoribbon devices and the on-off ratio, which is comparable with values achieved in nanoribbon devices, can be tuned by varying the neck width. The graphene nanomesh may also be incorporated into FET-type sensor devices. | 11-29-2012 |
20130011914 | BIOCHIP - A biochip including a metal nanoparticle layer on a multilayer substrate can perform qualitative and quantitative analyses simply without a separate tag. A biochip including a metal nanoparticle layer on a multilayer substrate and using a CMOS image sensor can be an economically beneficial biochip reusable and convenient in use by employing a relatively simple detection method without a need of using a separate tag. | 01-10-2013 |
20130040379 | Method for Measuring Low-Density Lipoprotein (LDL) Cholesterol and Test Piece for Measuring LDL Cholesterol - An LDL cholesterol measurement method that can be used with a test piece is provided. The LDL cholesterol measurement method for measuring LDL cholesterol in a sample has (A) a step of providing a total-cholesterol measurement portion and a non-LDL cholesterol measurement portion for measuring non-LDL cholesterol, which is cholesterol other than LDL cholesterol; (B) a step of measuring the total cholesterol in the sample in the total-cholesterol measurement portion; (C) a step of measuring the non-LDL cholesterol in the sample in the non-LDL cholesterol measurement portion; and (D) a step of obtaining the LDL cholesterol level in the sample by subtracting the non-LDL cholesterol value measured in the step (C) from the total-cholesterol value measured in the step (B). | 02-14-2013 |
20130189769 | BIOCHEMICAL SENSOR - A biochemical sensor includes a substrate with a printing surface, an intermediate layer, and a cover. The printing surface includes a reactive film, two electrode films, a conductive electrode film, and a referential electrode film. The conductive electrode film is arranged between the two electrode films. Each ends of the two electrode films contacts with the reactive film. One end of the conductive electrode film, proximate to the reactive film, contacts with one of the two electrode films. The referential electrode film and one of the two electrode films are arranged on the relative two sides of the printing surface. One end of the referential electrode film extends to contact with the reactive film. The intermediate layer has a notch corresponding to the reactive film, and the cover has an test slot corresponding to the notch. The intermediate layer and the cover are sequentially covered on the substrate. | 07-25-2013 |
20130288353 | BIOLOGICAL INDICATOR - A kinase is used in a biological indicator for validation of treatment processes designed to reduce the amount or activity of a biological agent in a sample. The indication can be used for validation of sterilisation treatment. The formation of ATP from a substrate comprising ADP is measured via the liciferin/luciferate system in a luminameter. Thermostable adenylate kinase from sulfolobus acidocaldarius is especially suitable for the validation of procedures to inactivate transmissable spongiform encephalopathy agents. | 10-31-2013 |
20130323828 | URINE TEST SHEET - A urine test sheet which can reduce the workload of a person performing a test through the use of a urine test sheet, caused by the above-mentioned temporary restriction and which makes it possible to obtain a determination result having high reliability. The urine test sheet includes a support, and a reaction reagent which is formed on the support, and by the urine test sheet being immersed in urine to be a specimen and then being taken out, shows a reaction for a prescribed subject to be tested after a prescribed period of time, wherein a detection member in a pad-like shape including the reaction reagent and a reaction-terminating agent having an action causing the reaction to terminate is formed on the support, the reaction-terminating agent is covered with a water-soluble material, and the water-soluble material causes the reaction-terminating agent to act by being dissolved by moisture in the urine. | 12-05-2013 |
20130330815 | Compositions, Devices And Methods For SERS And LSPR - The present invention relates to compositions, devices and methods for detecting microorganisms (e.g., anthrax). In particular, the present invention provides portable, surface-enhanced Raman biosensors, and associated substrates, and methods of using the same, for use in rapidly detecting and identifying microorganisms (e.g., anthrax). | 12-12-2013 |
20140024106 | MONITORING OF WOUNDS BY MEASUREMENT OF PROTEASE AND PROTEASE INHIBITOR LEVELS IN WOUND FLUIDS - A diagnostic test apparatus for determining a ratio of: (a) at least one endogenous protease enzyme inhibitor, to (b) at least one endogenous protease enzyme, in a sample of a wound fluid. Suitably the protease enzyme is a neutrophil elastase and the protease enzyme inhibitor is alpha-1-antitrypsin. Also provided are wound treatment systems comprising an apparatus according to the invention and a wound dressing comprising an oxidized cellulose. Also provided are methods of diagnosis, prognosis and treatment of wounds using the apparatus and systems of the invention. | 01-23-2014 |
20140099703 | Capillary Waveguide Cuvette - A cuvette for use with a spectophotometer having a capillary sample chamber having a volume of from 1 microliter to 1 femtoliter. | 04-10-2014 |
20140099704 | INCREASE IN STORAGE LIFETIME OF A THROMBIN SENSOR - A blood coagulation time measuring sensor comprising a surface, a resin layer applied thereto, including at least one substance with a detection function, characterized in that the resin layer comprises a lacquer system, wherein said lacquer system i) is suitable for immobilization of the at least one substance with a detection function on the surface; and ii) provides a negatively charged surface layer; iii) and allows the replacement of biological blood coagulation promoters by non-biological chemically inert and stable compounds. | 04-10-2014 |
20140193894 | SENSOR AND PACKAGE - A fluid sensor comprises a formed plastic body and a reagent. The body has a top face with an integral first surface. The body also has a bottom face opposed to the first surface and a sidewall that extends from the periphery of the top face. The first surface is adapted to accept a fluid sample. The reagent is disposed on the integral first surface and causes a color change detectable on the bottom face when the reagent reacts with an analyte in the fluid sample. | 07-10-2014 |
20140220670 | METHOD OF COMPONENT ASSEMBLY ON A SUBSTRATE - A method of component assembly on a substrate, and an assembly of a bound component on a substrate. The method comprises the steps of forming a free-standing component having an optical characteristic; providing a pattern of a first binding species on the substrate or the free standing component; and forming a bound component on the substrate through a binding interaction via the first binding species; wherein the bound component exhibits substantially the same optical characteristic compared to the free-standing component. | 08-07-2014 |
20140234950 | CULTURE CONTAINERS WITH INTERNAL TOP COATING OVER GAS BARRIER COATING AND ASSOCIATED METHODS - A container for culturing a test sample includes a molded monolithic single layer polymeric container body having an upwardly extending, visually transmissive wall with an inner surface and a wall thickness that is between about 0.2 mm and 10 mm. The container also has a thin gas barrier coating comprising silica on the inner surface of the sealed container body and an internal top coating on the gas barrier coating. The gas barrier and top coating are visually transmissive (after curing). The container includes a cap sealably attached to the container body. The sealed container has an oxygen transmission rate (OTR) after autoclaving and aging that is between about 0.0001 to about 0.04 (cc/package/day/atm). | 08-21-2014 |
20140248694 | Test Strip - The invention includes a base, a working wire, a grounding wire, a first division layer, a second division layer and a cover layer. The base has a reaction area. The working wire is formed with a first measure contact and a first bioreaction contact. The grounding wire is formed with a second measure contact and a second bioreaction contact. The first division layer and second division layer have a first inlet and a second inlet, respectively. The first inlet and the second inlet correspond to the reaction area in position to expose the first and second bioreaction contacts. The guiding trough is formed by the cover layer, the base and the first and second inlets. | 09-04-2014 |
20140302595 | NANOSENSORS AND METHOD OF MANUFACTURE - A nanosensor and methods to manufacture are disclosed. For example, a detection system for detecting the presence of a target substance can include a nanosensor that includes a sensing layer, and a plurality of sockets embedded within the body of the sensing layer, each socket having a physical profile matching a shape of the target substance such that, when target substances occupy the sockets, at least one measurable physical characteristic of the sensing layer changes. | 10-09-2014 |
20140370584 | SENSOR DEVICE - A sensor device includes a flow path and a metal layer disposed in the flow path. The flow path is configured to allow a sample containing analytes to flow and to allow a carrier to be disposed therein. The carrier has acceptors that are fixed on a surface thereof and specifically bound with the analytes for producing aggregates. The flow path includes an aggregate trapping section at which the analytes locally concentrate to the section. This sensor device has high detection sensitivity with a simple structure. | 12-18-2014 |
20140370585 | ENVIRONMENTAL SAMPLING ARTICLES AND METHODS - The present invention refers to articles for collecting samples from a surface, articles for microbiological analyses of said samples, and methods of use of said articles. The articles include sample collectors, sample housings with optional barrier layers, and sample-ready reagent strips comprising hydrophilic agents to grow and detect microorganisms. The disclosure includes methods to collect, detect, and quantify microorganisms in a surface sample. | 12-18-2014 |
20150031118 | Acoustic Mass Sensor - A mass sensor has a common RF input, a set of mass sensor cells, and a common hold input. Each of the mass sensor cells has a local input node coupled to the common RF input, a local output node, a mass-dependent RF filter that includes an electroacoustic resonator having receptors immobilized on a surface thereof, an RF detector, and a hold circuit having a local hold input. The RF filter, the RF detector and the hold circuit are connected in series between the local input node and the local output node. The common hold input is coupled to the local hold inputs of the hold circuits of at least a subset of the mass sensor cells. | 01-29-2015 |
20150104861 | SYSTEM AND METHOD FOR DETECTION OF A CONTAMINATED BEVERAGE - An apparatus may be configured to test a beverage, the apparatus may include but is not limited to, a beverage container that may be configured to hold a beverage, wherein the beverage container may include a material. An indicator may be chemically bonded to at least a portion of the material of the beverage container, wherein at least the portion of the material of the beverage container may include the indicator, wherein the indicator may be associated with at least part of a brand profile to identify a beverage brand's beverage, wherein the indicator may visibly react when the indicator is contacted with the beverage to show whether the beverage may be identified as the beverage brand's beverage, and wherein the visible reaction may be shown on at least the portion of the material of the beverage container via the indicator chemically bonded to at least the portion of the material of the beverage container. | 04-16-2015 |
20150316485 | Analytical Aid - A process for producing an analytical aid for the detection of at least one analyte in a sample, such as a body fluid. The analytical aid includes at least one housing and at least one test element including at least one test chemistry. The process includes the following steps: providing the test element; and producing at least one housing part of the housing using at least one shaping process, during which the test element is connected to the housing part. | 11-05-2015 |
20150338350 | DEVICE FOR MONITORING BIOFILM - The present invention relates to a device for monitoring a biofilm, which can monitor a formation state of the biofilm by using a biofilm shadow image. According to one embodiment of the present invention, the device for monitoring a biofilm can comprise: a water tank for storing water; a monitoring substrate arranged inside the water tank and surface-treated so as to accelerate the biofilm formation; a light-emitting module located at an upper portion of the monitoring substrate so as to emit light in a monitoring substrate direction; and an image sensor unit arranged below the monitoring substrate so as to capture a shadow image of the biofilm, which is formed on the monitoring substrate. | 11-26-2015 |
20150344829 | CELL CULTURE BAG AND METHOD FOR MANUFACTURING CELL CULTURE BAG - A cell culture bag is provided. The cell culture bag includes: an external film of the cell culture bag; at least one sensor chip arranged on a culture fluid side of the external film, the at least one sensor chip including a layer reacting to an object to be detected; and a permeable film that covers a culture fluid side of the sensor chip, the permeable film permeating the object to be detected. | 12-03-2015 |
20160003747 | Apparatus for two-step surface-enhanced raman spectroscopy - A kit of components is used in the detection, identification, analysis, and quantitation, by SERS, of a designated target analyte in a sample, comprising: packaging means normally containing a SER-active device component providing a support structure including a SER-active material, a collection component, a container component containing a liquid reagent comprised of a SER-active material, and a component for introducing the liquid reagent into the SER-active device. At least one of the SER-active materials is functionalized with an agent having the specific capability of binding the designated target analyte, and is accessible for the deposit thereon of liquid analyte samples. The SER-active device is constructed for receiving the liquid reagent and for enabling irradiation and collection of Raman-scattered radiation, by and from a Raman spectrometer, cooperatively generated by SER-active metals of the SER-active materials. | 01-07-2016 |
20160053294 | INTERACTIVE DEVICE FOR THE MICROBIOLOGICAL DETERMINATION OF ACTIVITIES BETWEEN NEIGHBORING COMMUNITIES WITHIN PREPARED NATURAL SAMPLES - A device for the microbiological detection and analysis of a controlled interface where known and controlled exposure of a sample of interest interacts with one of series of porous reactive zones in a manner that allows discernable activity to be detected. A favorable environment within the device allows agents emanating from the sample of interest to react with specific agents emanating from the porous reaction zone in a manner that is repeatable and precise. | 02-25-2016 |
20160115516 | RESISTIVE SENSOR BASED ON CONDUCTIVITY CHANGE OF CONDUCTIVE POLYMER AND MEASURING METHOD THEREOF - A resistive sensor for an analyte comprises a substrate, a conductive polymer layer and an oxidase layer. Hydrogen peroxide is produced via the reaction between analyte and oxidase when a liquid sample is applied to the sensor of the present invention. The produced hydrogen peroxide can oxidize peroxidase, which can be reduced by oxidizing the conductive polymer, thus resulting in decreased conductivity of the conductive polymer for determining the analyte concentration in the liquid sample. The present invention may be used for developing miniaturized and disposable electronic microsensors with high sensitivity and fast response, which can detect analyte level in typical physiological environment for routine monitoring. | 04-28-2016 |
20160131590 | BIOCHIP FOR MEASURING BLOOD GLUCOSE LEVELS, AND BLOOD GLUCOSE METER FOR SMARTPHONE, CONTAINING SAME - Disclosed are a biochip for measuring blood glucose levels and a blood glucose meter for a smartphone including the same. The biochip for measuring blood glucose levels includes: a substrate, one surface of which is provided with a blood glucose inflow region into which blood glucose flows and with a reaction region that is connected to the blood glucose inflow region and has a recess formed therein, a porous separator disposed on the blood glucose inflow region to face the surface of the substrate, and silica nanoparticles and a reaction reagent distributed on the reaction region of the substrate. Thereby, blood glucose levels can be measured using such a biochip, which is easy to carry, together with a CMOS image sensor, and particularly, blood glucose levels can be simply measured using a CMOS image sensor provided to a smartphone, and blood glucose levels can be quantitatively measured and checked using a blood glucose meter application installed on a smartphone. | 05-12-2016 |
20160178605 | Electrical Cell-substrate Impedance Sensor (ECIS) | 06-23-2016 |
20160252534 | Methodologies and Reagents for Detecting Fibrinolysis and Hyperfibrinolysis | 09-01-2016 |
20220137032 | BIOMATERIAL ASSAY STRIP - The present invention provides a biomaterial assay strip as a strip-type platform for use in a point-of-care test device. The strip includes a porous matrix bearing micropores and composed of materials comprising a copolymer selected from the group comprising polysulfone, polyethersulfone, and polyarylsulfone in order to increase separation efficiency of the blood cells contained in a sample and to improve accuracy and reproducibility of measurements with a small amount of blood, wherein the matrix comprises an enzyme, a dye, and a hydrophilic polymer material therein, which all respond to a biomaterial and wherein the matrix develops a color as the biomaterial contained in the sample which is brought into contact with the upper layer of the matrix and then diffuses to the lower layer of the matrix, thereby assaying the biomaterial. | 05-05-2022 |