Class / Patent application number | Description | Number of patent applications / Date published |
435286500 | Including liquid flow, level, or volume control | 41 |
20080261295 | Cell Sorting System and Methods - Apparatus and Methods are provided for a microfabricated fluorescence activated cell sorter based on a switch for rapid, active control of cell routing through a microfluidic channel network. This sorter enables low-stress, highly efficient sorting of populations of small numbers of cells (i.e., 1000-100,000 cells). The invention includes packaging of the microfluidic channel network in a self-contained plastic cartridge that enables microfluidic channel network to macro-scale instrument interconnect, in a sterile, disposable format. Optical and/or fluidic switching forces are used alone or in combination to effect switching. | 10-23-2008 |
20090023199 | MICRO-ORGANISM PRODUCTION SYSTEM AND METHOD - A micro-organism production system having at least one micro-organism growth unit for maintaining therein micro-organisms in solution. Upon the receipt of a predetermined amount of live organisms, liquid and nutrients within the at least one micro-organism growth unit and the application of radiation thereto, the system produces the rapid growth of micro-organisms within the at least one micro-organism growth unit. | 01-22-2009 |
20090068725 | BIOREACTOR FOR METHANIZATION OF BIOMASS HAVING A HIGH SOLIDS FRACTION - A bioreactor having improved gas yield is described, wherein the necessary residence time of the biomass in the digestion tank is reduced. During the fermentation of dry, i.e. non-pumpable biomass, percolating juices, so-called percolate, is generated as a result of the moisture contained in the biomass, which percolate is withdrawn via a drainage system and, if necessary, recirculated from the top onto the biomass to be fermented. It has now been found that the biomass yield is significantly increased—in the region of between 10% and 40%—when the resultant percolate is not immediately withdrawn by way of the drainage system, but is accumulated in the digestion tank up to a specific level. This is achieved by a technical device wherein the digestion tank is liquid-tight, i.e. also the flap for loading and unloading the digestion tank must be liquid-tight and also be designed in a correspondingly solid manner in order to withstand the resultant liquid pressure. By linking the existing percolate drainage system with a percolate control system it is possible to adjust and control the liquid level of the percolate in the fermenting biomass in such a way that the biogas generation rate or the biogas yield is maximized. | 03-12-2009 |
20090130744 | Apparatus and method to measure platelet contractility - An apparatus and method for measuring blood platelet contractility, hereinafter called a “retractometer” is disclosed. Also disclosed is a system apparatus and method for automatically measuring platelet contractility in a plurality of samples, having an array of retractometer units and an electronic solenoid valve controller to fully automate screening in clinical and research situations and save costs in labor. | 05-21-2009 |
20090137027 | SOLID PHASE METHODS FOR POLYNUCLEOTIDE PRODUCTION - Polynucleotides having in excess of 1,000 nucleotides can be prepared using a solid phase synthesis technique. A feature of the technique is the use of a reusable solid support that contains covalently bound oligonucleotide. This covalently bound oligonucleotide is annealed to a bridge oligonucleotide, where the bridge is also annealed to a first oligonucleotide that forms a portion of the target polynucleotide. After the target polynucleotide is synthesized, it can be removed from the solid support under denaturing conditions, and the solid support re-used to prepare additional target polynucleotides. The yield of the target polynucleotide increases when shearing force is applied to the solid support that is linked to the growing oligonucleotide. This shearing force is thought to extend the growing end of the oligonucleotide away from contact with other oligonucleotide bound to the solid support and make that end more accessible to annealing with solution oligonucleotide. The synthesis is conveniently accomplished on a porous frit, where reagents and washing solutions are pumped through the frit. | 05-28-2009 |
20090142824 | INCUBATOR - To improve an incubator. In an incubator for incubating a culture medium accommodated in an incubation space defined in a storage. A heater to control a temperature of the water stored in a water storing structure which is in the bottom side of the storage, and to keep the temperature of the water a predetermined temperature. A water supplier to supply the water to the water storing structure when the water has been decreased. In the incubator when the water supplier supplies the water during the culture medium is incubated, the water supplier decreases the amount of water supplied per an unit time than the amount of water supplied during the culture medium is not incubated. | 06-04-2009 |
20090221057 | Bio-Breeder System for Biomass Production - A system for converting flue gases into useful biofuels and oxygen. The system uses flue gases and thermal energy from smokestack industries to grow algae in a controlled environment. The flue gases are used as nutrients for the growth of algae through photosynthesis which is then processed into biofuels. The algae growth occurs in a controlled environment to minimize contamination of the algae as well as to optimize the algae growth. Sunlight and artificial light is modulated to provide the optimum light source for the photosynthesis process. | 09-03-2009 |
20090269836 | Apparatus and Method for Analysing a Biological Sample in Response to Microwave Radiation - Apparatus and method of exposing a chemical, biological or biochemical sample to radiation. A sample in liquid or vapour phase is segmented and conveyed along a sample path. At least one generator or source for generating electromagnetic radiation is directed at the sample and at least one of reflected, emitted and transmitted radiation is measured at least one point along the sample path. In one embodiment, the sample is a luminescent culture produced by a continuous culture system. | 10-29-2009 |
20090286307 | Automatic treatment system of leftover food treating device - The present invention relates to an automatic treatment system of a leftover food treating device comprising a setting means for receiving an output voltage of a voltage supplying means and setting control signals of the leftover food treating device; a controlling means for receiving input data through the setting means and controlling the operational state of the leftover food treating device; a sensing means for inputting measured data to the controlling means; a driving means for receiving the output signals of the controlling means; a displaying means for displaying the operational states of the setting means, the sensing means, the driving means, and the controlling means; and an alarming means for displaying an alarm setting value through the displaying means and outputting a predetermined alarm sound, in the case of the alarm setting value of a program preset to the controlling means. | 11-19-2009 |
20090311772 | MICRO REFINERY FOR ETHANOL PRODUCTION - A micro refinery system includes a fermentation tank, a distillation tube and a membrane ethanol separation mechanism. A batch that includes sugar, yeast and water is mixed in the fermentation tank. Sensors detect the physical characteristics of the batch and the operating status of the system. The sensors are coupled to a control system that compares the detected processing information to a look up table to determine if the system is operating under optimum ethanol productivity conditions. If the sensors detect a problem with the batch, the control system can add chemical components to the batch to correct the chemical imbalance. The system can also facilitate remote operations by transmitting sensed information to an operator computer and receiving control commands from the operator computer. | 12-17-2009 |
20100028980 | REAL-TIME PCR IN MICRO-CHANNELS - The present invention relates to methods for amplifying nucleic acids in micro-channels. More specifically, the present invention relates to methods for performing a real-time polymerase chain reaction (PCR) in a continuous-flow microfluidic system and to methods for monitoring real-time PCR in such systems. | 02-04-2010 |
20100105129 | Biomass production system - A system preferably for light irradiation, wherein the system includes a support structure, wherein the support structure is able to accommodate an array of vessels capable of receiving light; the system includes a buoyancy support system and a feeding harvesting system, wherein the buoyancy support system is in fluid and data communication with the array of vessels to regulate the amount of light introduced into the vessels within a fluid medium. | 04-29-2010 |
20100159571 | BIOGAS PLANT FOR METHANIZING BIOMASS HAVING A HIGH SOLIDS FRACTION - A biogas plant for methanizing biomass having a high solids fraction includes a digestion tank system having a plurality of digestion tanks adapted to be closed in a gas- and liquid-tight manner, each of which includes a charging and withdrawing opening for charging with biomass and withdrawing the biomass, a biogas discharge means, a percolate reservoir, a percolate drainage means for discharging percolate from the plurality of digestion tanks and supplying the percolate to the percolate reservoir, a percolate distributing means for distributing the percolate from the percolate reservoir over the biomass in the plurality of digestion tanks, and a percolate regulating means for regulating the percolate level in the plurality of digestion tanks. The percolate reservoir includes a first and a second percolate container, and supplying and discharging of percolate to/from the first and/or the second percolate container takes place with the aid of the percolate regulating means. | 06-24-2010 |
20100184199 | Well Plate Reactor - A well plate and its supporting devices provide capabilities found in larger fermenters, such as controlling the oxygen level, the pH level, and temperature of the contents of the well. The well plate includes a plurality of wells, each of which can be independently controlled. Apertures in the wells, for example, provide access for a gas supply and sensors within each well provide data relating to, e.g., oxygen and/or pH level in the well. A control system controls the gas supply for each well based on the information provided by the sensor within the well. Similarly, temperature control elements, such as a heater or cooler, is placed in thermal contact with the interior of the well, as is a temperature measurement element. A control system can independently control the temperature of the contents of the well based on information provided by the temperature measurement element for that well. | 07-22-2010 |
20100216223 | REAGENT PREPARING DEVICE, SPECIMEN MEASURING DEVICE AND REAGENT PREPARING METHOD - A reagent preparing device for preparing a reagent to be supplied to a measurement device for measuring a specimen, comprising: a first liquid storage unit for storing a first liquid; a reagent storage unit for storing a prepared reagent, including the first liquid and a second liquid different from the first liquid; a first liquid discarding unit for discarding the first liquid stored in the first liquid storage unit; and a controller configured for measuring an accumulated time of the first liquid in the first liquid storage unit; and controlling the first liquid discarding unit to discard the first liquid stored in the first liquid storage unit when the accumulated time reaches a predetermined time is disclosed. A specimen measuring device and a reagent preparing method are also disclosed. | 08-26-2010 |
20100216224 | REAGENT PREPARING DEVICE, SPECIMEN PROCESSING SYSTEM AND REAGENT PREPARING METHOD - A reagent preparing device capable of supplying a mixed solution, including a first liquid and a second liquid, to a measurement section for measuring a specimen using the mixed solution as a reagent, the reagent preparing device comprising: a first mixed solution container for accommodating the mixed solution; a second mixed solution container for accommodating the mixed solution; and a controller for controlling supply of the first liquid and the second liquid to supply the first liquid and the second liquid to the first mixed solution container, and to supply the first liquid and the second liquid to the second mixed solution container, is disclosed. A specimen processing system, and a reagent preparing method are also disclosed. | 08-26-2010 |
20110039328 | TISSUE PIECE TREATING APPARATUS - The present invention can solve such a problem that a conventional tissue piece treating apparatus has difficulty of reduction in size and restriction on installation and stopping subsequent treatment operations when the amount of chemical supplied to a processing chamber is insufficient. The tissue piece treating apparatus comprises: new chemical tanks | 02-17-2011 |
20110059519 | Automatic System of Isolating and Incubating Circulating Tumor Cells - The present invention is apllied in fields like biological medicine and tissue engineering. A fluid control system in a cell isolation and culture system is used to automatically process sample preparation, circulating tumor cell (CTC) isolation, plate changing and cell culturing. By using the present invention, time and labor are saved; moreover, the present invention has a small size and is easily carried. | 03-10-2011 |
20110091962 | Automated Stainer Having Stain Level Detection - An automated slide staining apparatus for staining slide samples is disclosed. The slide staining apparatus includes cuvette chambers that are flooded with solutions to cover a slide fitting within the cuvette chamber. Filling and emptying the chamber accomplishes a dipping function on the slide. The cuvette chamber includes a drainage flute and level detectors therein for proper fluid use and removal. The staining apparatus is useful to perform Gram stains, hematology cytology, dermatology cytology, fecal cytology and the like. Further, the method of using the slide stainer of the present invention along with the process of staining slides using the slide stainer of the present invention is disclosed. | 04-21-2011 |
20110177583 | Automated rinse water and body fluid bioagent detection - Testing of the foot soldier or other person on the battlefield for bioagent contamination is facilitated by a computer controlled portable testing unit that combines a sink or other receptacle ( | 07-21-2011 |
20120009664 | FERMENTER FOR BIOGAS PLANTS, COMPRISING A SUBMERSIBLE MOTOR-DRIVEN STIRRER VERTICALLY ADJUSTABLE BY MEANS OF A MOTOR - A fermenter for biogas plants, including a submersible motor-driven stirrer that can be vertically adjusted by means of a motor. During operation of the biogas plant, the fermenter is filled, to a level, with substrate that is to be fermented, and the agitator blades of the submersible motor-driven stirrer are fully immersed in the substrate. According to the invention, a level gauge is provided, by means of which the level of the substrate is detected and a corresponding level measuring signal is generated as an actual level signal. Furthermore, a control device is provided, to which the level measuring signal is fed and which controls the vertically adjusting motor for the submersible motor-driven stirrer in such a way when a lower level is detected that the stirrer is lowered and the agitator blades continue to be fully immersed in the substrate. | 01-12-2012 |
20120107921 | MODEL BASED CONTROLS FOR USE WITH BIOREACTORS - Embodiments of the present invention include model-based controls to control photobioreactor operation and the growth of algae for use as a biofuels feedstock. In some embodiments, the model-based control can accounts for future conditions such as weather, product pricing, customer demands and/or other variables to operate the reactors in a manner that optimizes product revenues, minimizes costs or energy, maximizes photosynthetic or energy balance efficiency, and/or any combination of the aforementioned factors. | 05-03-2012 |
20120288920 | DISPOSABLE CHIP-TYPE FLOW CELL AND FLOW CYTOMETER USING THE SAME - The object of the present invention is to provide (1) a cell sorter, (2) a flow cytometer capable of detecting sideward scattered light, (3) a method for accurately measuring cell concentration, (4) a method for multicolor staining analysis without a fluorescence correction, and the like, which satisfy requirements that carry-over and cross contamination of samples do not occur. | 11-15-2012 |
20130071914 | METHOD FOR STUDYING FLOATING, LIVING CELLS - Disclosed is a method of studying floating living cell by confining the cells floating in an aqueous medium in picowells located on a bottom surface of a top wall of a chamber. Disclosed is also a picowell-bearing device for the study of cells comprising a chamber having at least one picowell on a bottom surface of the chamber. Also disclosed is a picowell-bearing device for the study of cells comprising a chamber having at least one picowell on an internal surface and at least one moveable wall, a force applicator configured to removeably apply a substantially uniformly distributed force around the periphery of the moveable wall in a direction to retain the moveable wall secured to the chamber. | 03-21-2013 |
20130143307 | AUTOMATIC CULTURE DEVICE - In order to uniformly sow cells on the culture surface of a cartridge-type closed culture vessel and remove bubbles contaminating in liquid culture medium in the course of automatic culture, an automatic culture equipment is provided with a flow-controlling mechanism section for solving the non-uniformity in cell distribution by, after filling up a culture space in the cartridge-type closed culture vessel, said cartridge-type closed culture vessel being in an upright position, with cell suspension, turning the cartridge-type closed culture vessel into a horizontal position, and then repeatedly supplying the cell suspension and sucking the same multiple times to thereby create a mixing flow in the cell suspension. In this process, the liquid in channels is efficiently sent by applying a reduced pressure and an elevated pressure respectively to a channel on one side and a channel on the opposite side, using two syringes and check valves connected to the channels, to thereby load forces to the liquid from both sides. The liquid can be sent without any cell loss by conducting the same operations of the flow-controlling mechanism section in a tank and in a cell bag. | 06-06-2013 |
20130203157 | MICROFLUIDIC DEVICE FOR COUNTING BIOLOGICAL PARTICLES - A particle counter for analyzing blood has features which provide for automatic operation and preferably, also provide for portable use in a low resource setting. In a preferred embodiment, preferred embodiment, the device is used to obtain CD4 counts for AIDS diagnosis. | 08-08-2013 |
20130302882 | METHOD FOR STERILIZING SEPARATION MEMBRANE MODULES, STERILIZATION DEVICE, AND APPARATUS FOR PRODUCING CHEMICALS - A method of sterilizing a separation membrane module reduces damage of a ceramic separation membrane, a sterilization process device achieves the method of sterilizing, and an apparatus produces chemicals. The method of sterilizing the separation membrane module includes a ceramic-containing separation membrane including a temperature raise step of raising the temperature of the separation membrane module to a predetermined sterilization temperature by feeding sterilization water having a controlled temperature and pressure so that a rate of temperature change of the separation membrane module is 6.0° C. or less per minute, and a sterilization step of sterilizing the separation membrane module at a predetermined temperature for a predetermined time. | 11-14-2013 |
20130323824 | CONTROL DEVICE FOR A FOOD WASTE DISPOSAL APPARATUS - This invention relates to a control device for a food waste disposal apparatus. The control device is comprised of a touch screen, a memory device to perform a specific function to control the food waste disposal apparatus. The touch screen of the control device displays a plurality of input button images so that a user can click them by fingers to prosecute. The main menu of the touch screen is comprised of auto working mode, total monitoring mode, manual working mode, time setting mode, alarm message mode and function setting mode. The sub-menu of function setting mode further includes cumulative weight setting and part replacement cycle setting. | 12-05-2013 |
20140057338 | Automated Staining and Decolorization of Biological Material - An improved method and apparatus for staining samples of biological material for accurate analysis of the sample. Biological material is applied to a substrate, such as a microscope slide. The biological specimen is then stained with a selected staining composition, which may be gentian violet for a Gram's Stain analysis. The stained biological material is at least partially decolorized and the level of decolorization is analyzed optically. If necessary, the decolorizing step and the optical analysis steps are repeated until a selected level of decolorization is obtained. | 02-27-2014 |
20140295532 | SYSTEMS AND METHODS FOR PRODUCING BIOPRODUCTS - The present disclosure is directed to systems and methods for sampling and/or controlling the productivity of a bioreactor. | 10-02-2014 |
20140377850 | METHODS AND SYSTEMS FOR CONTROL OF MICROFLUIDIC DEVICES - The present invention provides control methods, control systems, and control software for microfluidic devices that operate by moving discrete micro-droplets through a sequence of determined configurations. Such microfluidic devices are preferably constructed in a hierarchical and modular fashion which is reflected in the preferred structure of the provided methods and systems. In particular, the methods are structured into low-level device component control functions, middle-level actuator control functions, and high-level micro-droplet control functions. Advantageously, a microfluidic device may thereby be instructed to perform an intended reaction or analysis by invoking micro-droplet control function that perform intuitive tasks like measuring, mixing, heating, and so forth. The systems are preferably programmable and capable of accommodating microfluidic devices controlled by low voltages and constructed in standardized configurations. Advantageously, a single control system can thereby control numerous different reactions in numerous different microfluidic devices simply by loading different easily understood micro-droplet programs. | 12-25-2014 |
20150010990 | INTEGRATED BIO-REACTOR MONITOR AND CONTROL SYSTEM - Systems and methods for automatically controlling conditions of a process are disclosed. In one example, a controller is programmed with a sequence of steps and parameters required to carry out a bioreactor process. A sensor system interacts with the bioreactor to receive information related to a condition of the bioreactor and/or receive a sample from the bioreactor, which it analyzes. The sensor system sends data signals related to the information and/or the sample to a controller, which determines a control signal based on the received information. The controller sends the control signal to the sensor system which, based on the control signal, performs an action that affects a condition of the bioreactor or affects the sensor system itself. | 01-08-2015 |
20150024472 | BIOLOGICAL GROWTH MONITORING AND PARAMETER EXTRACTION SYSTEM - A biological growth monitoring and parameter extraction system includes a comparison group platform and an experimental group platform. First environmental sensing modules of the comparison group platform extracts first environmental parameters of a biological comparison area, a first control module transmits the parameters to the experimental group platform, and a first biological inspection module extracts growth conditions of organisms of the biological comparison area. A biological experiment area of the experimental group platform emulates growth environment of the biological comparison area, second environmental sensing modules extract second environmental parameters of the biological experiment area, and the first environmental parameters are used as reference inputs of the experimental group platform, so as to enable the second control module to obtain an error value by comparing the second and the first environmental parameters. | 01-22-2015 |
20150050719 | DISPENSING ASSEMBLY - A dispensing assembly comprising a cartridge holder is presented. The cartridge holder can receive a cartridge for dispensing a fluid. The cartridge can comprise a reservoir for receiving the fluid. The reservoir can comprise an outlet. The reservoir can have an adjustable volume for forcing the fluid through the outlet. The cartridge can further comprise a nozzle for dispensing the fluid. The nozzle can be connected to the outlet. The dispensing assembly can further comprise an actuator for actuating the adjustable volume. The dispensing assembly can further comprise an impulse generator for imparting an impulse to the nozzle. The impulse generator can comprise an actor for contacting the nozzle. The dispenser assembly can further comprise a controller for controlling the actor and the impulse generator. | 02-19-2015 |
20150072401 | CULTURE VESSEL AND AUTOMATED CULTURE APPARATUS - In a closed system culture vessel to be used in an automated culture apparatus, some of the ports perform both liquid supply and gas supply functions. Culture medium is thereby made to flow always in one direction. The culture vessel is also configured so that, in the complete culture medium exchange process and the effluent recovery process for analyzing culture medium components, waste liquid medium does not get mixed into fresh culture medium. | 03-12-2015 |
20150079663 | SPECIMEN PROCESSOR - A dispensing unit that sucks and discharges a blood specimen via a nozzle. A liquid level-measuring unit that measures the liquid level height. A serum volume-estimating unit that estimates the volume of the serum separated in the blood specimen, on the basis of the total blood volume, said total blood volume corresponding to the volume of the blood specimen and having been derived from the liquid level height, and a hematocrit value. A residual volume-estimating unit that calculates the volume of the serum remaining after suction, on the basis of the serum volume estimated by the serum volume-estimating unit and the volume of the serum that is going to be sucked by the dispensing unit. A controller that controls the suction procedure of the dispensing unit so that the estimated residual volume is not less than the desired volume of the serum to be left in the blood collection tube. | 03-19-2015 |
20150079664 | Methods and Systems of Growing and Harvesting Cells in a Hollow Fiber Bioreactor System with Control Conditions - Embodiments described herein generally relate to methods and systems for using an air removal chamber as a control for a process in a cell expansion system. The air removal chamber may be mounted on a fluid conveyance assembly for use with the system. Fluid is pumped into a fluid containment chamber of the air removal chamber, in which the level of fluid in the fluid containment chamber may be monitored through the use of one or more sensors. The sensors are capable of detecting air, a lack of fluid, fluid, and/or a gas/fluid interface, e.g., an air/fluid interface, at measuring positions within the air removal chamber. Protocols for use with the system may include one or more stop conditions. In an embodiment, the stopping of a process is automated based on the detection of air, a lack of fluid, and/or a gas/fluid interface in the air removal chamber. | 03-19-2015 |
20160024455 | Method of Loading and Distributing Cells in a Bioreactor of a Cell Expansion System - One or more embodiments are described directed to a method and system for loading and distributing cells in a bioreactor of a cell expansion system. Accordingly, embodiments include methods and systems that may provide for adding a plurality of cells to a fluid within a bioreactor of the cell expansion system. A first percentage of the plurality of cells is allowed to settle in the bioreactor and a second percentage of the plurality of cells is allowed to settle outside of the bioreactor. The first percentage of cells is then expanded in the bioreactor. The second percentage of cells is wasted. | 01-28-2016 |
20160145559 | METHOD OF OPERATING CONTINUOUS STERILIZING APPARATUS, CONTINUOUS STERILIZING APPARATUS, FERMENTING SYSTEM, AND CONTINUOUS FERMENTING SYSTEM - A continuous sterilizing apparatus circulates, through members constituting a flow channel, a sterilizing medium that sterilizes the members to sterilize the members, circulates a sterilizing liquid subjected to sterilization treatment through pipes, performs a series of pieces of treatment including heating treatment, holding treatment, and cooling treatment on the sterilizing liquid, controls a flow rate, a temperature, and a pressure to be preset conditions, and switches a liquid to be circulated through the flow channel from the sterilizing liquid to a liquid to be sterilized. | 05-26-2016 |
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