Class / Patent application number | Description | Number of patent applications / Date published |
435252800 | Escherichia (e.g., E. coli, etc.) or salmonella | 18 |
20090053792 | OXYGEN-REGULATED MICROORGANISMS - The present invention relates to novel strains of microorganisms with oxygen-regulated metabolism. The microorganisms have higher growth rates and are more efficient than parental strains. The microorganisms may be used to produce a variety of products of interests, such as recombinant proteins, nucleic acids, such as DNA, amino acids, and chemicals. | 02-26-2009 |
20090053793 | Ethanol resistant and furfural resistant strains of E. coli FBR5 for production of ethanol from cellulosic biomass - Ethanol and furfural challenged strains of | 02-26-2009 |
20090061501 | Ethanol resistant and furfural resistant strains of E. coli FBR5 for production of ethanol from cellulosic biomass - Ethanol and furfural challenged strains of | 03-05-2009 |
20090275110 | Microorganism that Displays Biotin on Cell Surface - Provided is a microorganism that can display, on the cell surface, any molecules other than a molecule comprising amino acids, more specifically, a microorganism that displays biotin on a cell surface. The microorganism is capable of co-expressing a biotinylating enzyme and an acceptor peptide having a sequence recognized by the biotinylating enzyme, wherein the acceptor peptide is expressed on the cell surface, so that lysine of the acceptor peptide is biotinylated to display biotin on the cell surface. Also provided is a method for displaying an intended molecule, including not only a molecule comprising amino acids but also any molecules, on a cell surface of a microorganism. | 11-05-2009 |
20100167379 | BACTERIA FOR HIGH EFFICIENCY CLONING - Disclosed are novel bacterial hosts that are capable of high efficiency transformation with methylated and/or unmethylated nucleic acids, and that are bacteriophage resistant. Such bacteria contain: (1) an F′ episome that confers high efficiency transformability; (2) one or more mutations that allow transformation of methylated nucleic acids; (3) one or more mutations that allow transformation with unmethylated nucleic acids; and/or (4) one or more mutations that confer resistance to bacteriophage infection. Also disclosed are methods for transforming such bacteria, and kits that contain such bacteria (e.g., that have been made competent for transformation). | 07-01-2010 |
20100311146 | CELL CULTURE AND MIXING VESSEL - A mixing vessel ( | 12-09-2010 |
20110081708 | Method of Sequence Optimization for Improved Recombinant Protein Expression using a Particle Swarm Optimization Algorithm - An improved gene sequence optimization method, the systematic optimization method, is described for boosting the recombinant expression of genes in bacteria, yeast, insect and mammalian cells. This general method takes into account of multiple, preferably most or all, of the parameters and factors affecting protein expression including codon usage, tRNA usage, GC-content, ribosome binding sequences, promoter, 5′-UTR, ORF and 3′-UTR sequences of the genes to improve and optimize the gene sequences to boost the protein expression of the genes in bacteria, yeast, insect and mammalian cells. In particular, the invention relates to a system and a method for sequence optimization for improved recombinant protein expression using a particle swarm optimization algorithm. The improved systematic optimization method can be incorporated into a software for more efficient optimization. | 04-07-2011 |
20110136211 | Mist or Spray Microorganism Cultivation and Related Methods - Disclosed is an apparatus for culturing microorganisms and methods for using the same. | 06-09-2011 |
20110195483 | Non-Natural Amino Acid Replication-Dependent Microorganisms and Vaccines - Compositions and methods of producing vaccines, including methods wherein whole organism vaccines are provided with limited replication abilities, thereby increasing vaccine safety and efficacy, through the use of non-natural, unnatural, or non-naturally encoded amino acids. | 08-11-2011 |
20120015426 | BACTERIA FOR HIGH EFFICIENCY CLONING - Disclosed are novel bacterial hosts that are capable of high efficiency transformation with methylated and/or unmethylated nucleic acids, and that are bacteriophage resistant. Such bacteria contain: (1) an F′ episome that confers high efficiency transformability; (2) one or more mutations that allow transformation of methylated nucleic acids; (3) one or more mutations that allow transformation with unmethylated nucleic acids; and/or (4) one or more mutations that confer resistance to bacteriophage infection. Also disclosed are methods for transforming such bacteria, and kits that contain such bacteria (e.g., that have been made competent for transformation). | 01-19-2012 |
20130011906 | Chemical Additives to Make Polymeric Materials Biodegradable - The present invention is a new additive material that is physically blended with polymeric material to create at least a partially biodegradable product. | 01-10-2013 |
20130084622 | DEVICE AND METHOD FOR CONTINUOUS CELL CULTURE AND OTHER REACTIONS - Devices, systems, and methods for continuous cell culture and other reactions are generally described. In some embodiments, chambers (e.g., cell growth chambers) including at least a portion of a wall formed of a flexible member are provided. A retaining structure can be incorporated outside and proximate to the chamber such that when liquid is added to the chamber, the flexible member is consistently and predictably deformed, and a consistent volume of liquid is added. The flexible member can be formed of, in some embodiments, a gas-permeable medium. In some embodiments, reaction chambers can be arranged in a fluidic loop, and a bypass channel can be used to introduce and/or extract fluid from the loop without affecting loop operation. | 04-04-2013 |
20130344572 | Microbial Growth Enhancement From a Dry Film Additive - A hyperbranched polymer based on one or more repeating units of an AB | 12-26-2013 |
20140147908 | METHOD FOR SPLITTING DROPLETS ON DEMAND IN MICROFLUIDIC JUNCTION - The invention relates to a method for splitting droplets on demand in a microfluidic junction, comprising the supply channel, the first drain channel and the second drain channel, the method comprises the following steps:
| 05-29-2014 |
20140242673 | CHEMICALLY DEFINED CULTURE MEDIUM FOR FERMENTATION TO PRODUCE SUCCINIC ACID AND APPLICATION THEREOF - This invention belongs to the technical field of industrial microorganism fermentation and relates to a type of chemical defined medium used for succinic acid production by fermentation and its application. The chemical defined medium of this invention used for succinic acid production by fermentation includes conventional compositions and critical growth factor compositions. Said critical growth factor compositions include biotin or 5-ALA, niacin, amino acid, and methionine. This formula determines four critical growth factors of succinic acid fermentation through reasonable technical means. The culture medium is free of complicated and expensive nutritious compositions such as yeast powder and peptone. Reliance on expensive vitamin by production of succinic acid through fermentation in defined medium is avoided, so that production cost of succinic acid can be greatly lowered, and subsequent separation process can be simplified, constituting a key step of industrial production of succinic acid using chemical defined medium. | 08-28-2014 |
20160158756 | MAGNETIC SEPARATION FILTERS FOR MICROFLUIDIC DEVICES - A magnetic separation device has a membrane having a plurality of pores, a magnetically soft material layer disposed on the membrane, and a passivation layer disposed on the magnetically soft material layer. The magnetic separation device may be part of a microfluidic device having a lateral flow channel and a vertical flow magnetic separation filter. The magnetic separation device may be used to separate magnetically tagged particles, such as cells. | 06-09-2016 |
20160175634 | COMPOSITIONS INCLUDING MATRIX AND BIOMATERIAL, USES THEREOF AND METHODS OF USING THE SAME | 06-23-2016 |
20160251401 | METHOD FOR INCREASING ETEC CS6 ANTIGEN PRESENTATION ON CELL SURFACE AND PRODUCTS OBTAINABLE THEREOF | 09-01-2016 |