Class / Patent application number | Description | Number of patent applications / Date published |
435173500 | Membrane permeability increased | 52 |
20090081750 | TRANSFECTION IN MAGNETICALLY DRIVEN CONTINUOUS FLOW - Biological cells and other membranous structures are transfected in a flow-through system by first rendering the structures magnetically active such that they respond to a magnetic field, suspending the structures in a solution of an exogenous species with which the structures are to be transfected, then placing the suspension in a channel and using a moving magnetization pattern along the channel wall to cause the structures to travel through the channel. Along their path of travel, the structures pass a transmitter that emits transfection energy sufficient to cause the exogenous species in the suspension to permeate the structure membranes and enter the interiors of the structures. | 03-26-2009 |
20100021983 | Laser Dosimetry for the Optoperforation of Single Cells - A method of optoperforation of the membrane of a cell by application of laser pulses characterized by focusing the pulsed laser beam onto the cell membrane to be perforated, applying a series of laser pulses of predetermined pulse energy, measuring the oscillation time of the bubbles formed in the laser focus from the change in laser intensity of a test laser beam transmitted through the laser focus and caused by the bubbles in the laser focus, and increasing the pulse energy to a level at which the oscillation time of the bubbles attains a predetermined value. | 01-28-2010 |
20100086984 | OPTOINJECTION METHODS - Optoinjection method for transiently permeabilizing a target cell by (a) illuminating a population of cells contained in a frame; (b) detecting at least one property of light directed from the frame; (c) locating a target cell by the property of light; and (d) irradiating the target cell with a pulse of radiation. | 04-08-2010 |
20100196983 | Transformation of gram positive bacteria by sonoporation - The present invention provides a sonoporation-based method that can be universally applied for delivery of compounds into Gram positive bacteria. Gram positive bacteria which can be transformed by sonoporation include, for example, | 08-05-2010 |
20100203611 | NOVEL NUCLEAR TRANSLOCATION PEPTIDE - The present invention provides a peptide comprising amino acid sequences R I, F I and R I G C and containing 25 or fewer amino acid residues, and capable of transporting a functional molecule into a cell, and also into a nucleus, more efficiently than a previous PTD. | 08-12-2010 |
20110201075 | OPTOINJECTION METHODS - Optoinjection method for transiently permeabilizing a target cell by (a) illuminating a population of cells contained in a frame; (b) detecting at least one property of light directed from the frame; (c) locating a target cell by the property of light; and (d) irradiating the target cell with a pulse of radiation. | 08-18-2011 |
20120135493 | Methods for Phototransfecting Nucleic Acids Into Live Cells - The present invention includes methods for transferring a multigenic phenotype to a cell by transfecting, preferably by phototransfection, and locally transfecting a cell or a cellular process with a laser while the cell is bathed in a fluid medium comprising two or more nucleic acids, thereby introducing the nucleic acid into the interior of the cell. Expression of the nucleic acids results in a multigenic phenotype in the tranfected cell. | 05-31-2012 |
20120171746 | METHOD AND SYSTEM FOR MANIPULATION OF CELLS - The invention is directed to a method for the manipulation of at least one cell, the method comprising the steps of depositing a metal onto the surface of a substrate, placing the at least one cell at or near the surface of the substrate, and irradiating the surface of the substrate with at least one laser pulse. The inventive method is characterized by the formation of surface structures with a size of one micrometer or less on the surface of the substrate prior to depositing the metal thereon. The invention is also directed to a system for the manipulation of at least one cell, the system comprising a substrate with surface structures having a size of 1 micrometer or less, wherein a metal is deposited on the surface structures, and wherein the system further comprises a laser for irradiating the surface structures. | 07-05-2012 |
20120270293 | STANDARDIZATION OF TISSUE SPECIMEN PRESERVATION BY ULTRASOUND AND TEMPERATURE CONTROL - A tissue sample preservation process and device for improving and standardizing tissue preservation procedure, including placing tissue specimens in a cold fixative, performing fixative penetration at a refrigerated temperature, and accelerating fixative penetration by ultrasound. Also disclosed is the application of ultrasound and temperature control in the dehydration, clearing, and impregnation steps. | 10-25-2012 |
20130071905 | PLASMA IRRADIATION DEVICE FOR SUBSTANCE INTRODUCTION AND SUBSTANCE INTRODUCTION METHOD USING PLASMA IRRADIATION DEVICE - Disclosed is a liquid culture medium for substance introduction, which is capable of increasing the survival rate of cells after substance introduction as much as possible when the cells are irradiated with plasma for the purpose of introducing a target substance into each of the cells. Specifically disclosed is a liquid culture medium for substance introduction, which is used for the purpose of introducing a predetermined target substance into a cell and enables introduction of the target substance into the cell by having the cell in the liquid culture medium, which contains the target substance, irradiated with a plasma jet. The liquid culture medium contains a damage preventing component that prevents the cell from damage due to the plasma jet. | 03-21-2013 |
20130122564 | METHODS AND DEVICES FOR MANIPULATION OF TARGET CELLS USING A COMBINED APPLICATION OF ACOUSTICAL AND OPTICAL RADIATIONS - A method of applying a nondestructive mechanical force on one or more cells in aqueous environment by inducing heat generated acoustic pressure pulses. The method comprises providing an energy transmission pattern to induce the applying of a desired nondestructive mechanical force on a at least one cell by forming a plurality of heat generated acoustic pressure pulses in an aqueous environment and instructing the radiation of a target area in proximity to the at least one cell in the aqueous environment with light energy according to the energy transmission pattern. | 05-16-2013 |
20130230895 | METHOD AND DEVICE FOR UNIFORMLY TREATING ADHERENT CELLS - The invention relates to a method for subjecting adherent cells to at least one electric field, in which the electric field is generated by applying a voltage to at least two active electrodes | 09-05-2013 |
20140206059 | Transcriptome Transfer Produces Cellular Phenotype Conversion - The present invention includes methods for effecting phenotype conversion in a cell by transfecting the cell with phenotype-converting nucleic acid. Expression of the nucleic acids results in a phenotype conversion in the transfected cell. Preferably the phenotype-converting nucleic acid is a transcriptome, and more preferably an mRNA transcriptome. | 07-24-2014 |
20150328313 | PHOTOACTIVATED MOLECULES FOR LIGHT-INDUCED MODULATION OF THE ACTIVITY OF ELECTRICALLY EXCITABLE CELLS AND METHODS OF USING SAME - Methods and compositions modulate the activity of electrically excitable cells. Photovoltaic compounds which, upon exposure to light energy, increase or decrease the electrical activity of cells. These supplement and/or replace of vision based on the conversion of light energy to electrical energy within certain cells of the visual system. A “patch” or bridge to circumvent one or more defective, damaged, or diseased cells in the visual system. Additionally, in several embodiments, subjects with normal vision can benefit from the methods, compositions, systems, and/or devices disclosed herein as normal visual acuity can be heightened. The exposure induces an energy (e.g., a receipt of light energy, conversion to electrical energy, and passage of that electrical energy) from the photovoltaic compound to the cell, thereby altering the transmembrane potential of the cell and/or the opening of one or more ion channels, thereby modulating the activity of the electrically excitable cell. | 11-19-2015 |
20150337289 | METHODS AND DEVICES FOR MANIPULATION OF TARGET CELLS USING A COMBINED APPLICATION OF ACOUSTICAL AND OPTICAL RADIATIONS - A method of applying a nondestructive mechanical force on one or more cells in aqueous environment by inducing heat generated acoustic pressure pulses. The method comprises providing an energy transmission pattern to induce the applying of a desired nondestructive mechanical force on a at least one cell by forming a plurality of heat generated acoustic pressure pulses in an aqueous environment and instructing the radiation of a target area in proximity to the at least one cell in the aqueous environment with light energy according to the energy transmission pattern. | 11-26-2015 |
435173600 | Electroporation | 37 |
20080213854 | DEVICE AND METHOD FOR STABILISING THE FLOW THROUGH A CHAMBER | 09-04-2008 |
20080213855 | Planar electroporation apparatus and method - An electroporation apparatus provides for the electroporation of adherent cells attached to an electrode surface or suspended cells in close proximity to an electrode surface. In one embodiment, the electrodes are transparent to allow cell viewing using a microscope or an automated image analysis machine. The geometry of the electrodes and associated electrically non-conductive structures may provide for well-defined regions of electroporated and non-electroporated adherent cells with a clearly defined interface between these regions, facilitating comparison of electroporated cells and non-electroporated cells, and evaluation of transfer of material from cell to cell via intercellular gap junctions. | 09-04-2008 |
20080220493 | COMPOSITE ELECTROPORATION PLATE WITH INTERCHANGEABLE WELL INSERTS - Electroporation on a plurality of samples of membranous structures is performed in an electroporation well plate that includes a frame that can hold a plurality of well strips to form a two-dimensional array of wells, and a set of well strips, the set containing strips that differ in the number of wells while having the same outer dimensions and hence being interchangeable, thereby allowing the user to select strips appropriate for a given electroporation procedure, and allowing the manufacturer to replace defective strips without rejecting an entire well plate when a small number of wells is found to be defective. | 09-11-2008 |
20080280340 | Method and Apparatus for Bacterial Transformation by Electroporation with Waveforms Incorporating Pulsed Rf Between 3 and 125 Mhz - A method and apparatus for electroporation includes placing a mixture of bacterial suspension and transforming DNA into an electroporation cuvette. The resulting sample is subjected through a current-limiting device to a complex 5 waveform including a burst of high-voltage radio-frequency current, which in some embodiments is superimposed on a biphasic high-voltage DC pulse, and in other embodiments on a high-voltage lower-frequency AC burst. The total waveform has at least an initial portion greater than eleven thousand volts per centimeter of electrode spacing, and a later portion in some embodiments is reduced to less than thirty percent 10 of magnitude of the initial portion. Transformed bacteria are selected by culture in selective medium in an embodiment. The high-voltage radio-frequency current is between 3 and 125 MHz, and in an embodiment is 24 MHz. | 11-13-2008 |
20080280341 | System And Method For Local Field Stimulation - A system is provided for stimulating one or more cells, wherein the stimulation is sub-threshold and may alter a transmembrane potential of the one or more cells. For some populations of cells it may be possible to affect the transmembrane potential to gain a therapeutic benefit. Cells of the sino-atrial node spontaneously depolarize predominantly due to the slow depolarization of transmembrane potential. The present system may provide sino-atrial cells with a local field stimulation that while not eliciting an action potential may nonetheless alter local transmembrane potential. Such alteration of transmembrane potential may permit an increase or decrease in a rate of depolarization, and hence modify heart rate. | 11-13-2008 |
20090004717 | Device and Method to Facilitate Directed Delivery and Electroporation Using a Charged Stream - A method for facilitating a delivery of a molecule into an interior space of a cell includes the steps of introducing a molecule into a biological structure comprising a cell and applying a substantially continuous low-level electric field, in the form of non-thermal plasma (ionized gas) generated by a direct current voltage applied to an electrode, to the molecule and biological structure. The field is applied for a duration sufficient to effect a change in porosity the cell of the biological structure sufficient to facilitate an entry of a desired molecule into an interior thereof. | 01-01-2009 |
20090017517 | Preparation of Negative-Stranded RNA Viruses by Electroporation - The present invention encompasses methods of preparing non-segmented negative-stranded RNA viruses from cells utilizing electroporation. | 01-15-2009 |
20090170177 | STEM CELL TRANSFECTION METHOD - Stem cell transfection method. The stem cell infection method of the invention comprises providing a stem cell; positioning the stem cell at a buffer, wherein the buffer contains a foreign material; electroporating the stem cell in the buffer; and culturing the stem cell. | 07-02-2009 |
20090209017 | Electroporation Cuvette With Spatially Variable Electric Field - An electroporation cuvette is constructed with electroporation electrodes arranged in non-parallel relation to form a gap whose width varies with the location within the cuvette, plus a pair of positioning electrodes that are arranged to cause electrophoretic migration of biological cells within the cuvette according to cell size. Once the cells, suspended in a solution of the impregnant, are distributed in the cuvette by the positioning electrodes, electric field pulses are generated by the non-parallel electroporation electrodes. Because of their distribution in the cuvette, the various cells will experience voltage differentials across their widths that approach uniformity regardless of cell diameter, since the larger cells will be positioned at locations where the gap between the electrodes is greater and the smaller cells at locations where the gap is relatively small while the voltage drop across the entire gap is uniform along the length of the cell. The voltage differential across the width of the cell is thus roughly paired with the cell diameter, and this reduces the disparity in voltage differential that cells of different sizes would otherwise experience with parallel electrodes. | 08-20-2009 |
20090286297 | APPARATUS AND METHOD FOR TIP ALIGNMENT IN MULTIWELL PLATES - Apparatuses and methods of aligning at least one tip of a tip manifold with a plurality of wells of a multiwell plate. The tip manifold includes a plate, at least one tip depending from the plate, a first tip alignment pin depending from the plate, and a second tip alignment pin depending from the plate. The second tip alignment pin opposes the first tip alignment pin. The multiwell plate includes a body defining a plurality of non-porous wells for holding biological material, a first alignment hole, and a second alignment hole. The second alignment hole opposes the first alignment hole. | 11-19-2009 |
20090305380 | ELECTROPORATION OF ADHERENT CELLS WITH AN ARRAY OF CLOSELY SPACED ELECTRODES - Adherent cells and other membranous structures that are immobilized on a solid surface are transfected by electroporation in which the electric field is produced by a array of closely spaced electrodes positioned above the surface. Each electrode is substantially smaller in at least one lateral dimension than the dimensions of a single cell, and the electrodes in each pair are spaced apart by distances selected such that that a maximum of one cell will reside within the field produced by each pair, and the distance of the electrodes above the surface to which the cells are adherent is small enough to place the cell within the resulting electric field and yet great enough to avoid contact of the electrodes with the cell membrane. | 12-10-2009 |
20090317883 | INDIVIDUAL-CELL ELECTROPORATION USING AREA-FOCUSED ELECTRIC FIELDS - Electroporation is performed on a population of cells, liposomes, vesicles, or other membrane-encased structures with uniform results regardless of size variations within the population, by drawing the membrane-encased structures into micron-sized openings that contain paired electrodes. An electric potential is then imposed between the paired electrodes to permeabilize only that portion of each cell that extends into the openings and resides within the electric field focused in the area between the electrodes. | 12-24-2009 |
20100068780 | METHOD FOR THE SELECTION AND/OR THE PROCESSING OF PARTICLES, IN PARTICULAR CELLS - Method for the selection or the processing of first particles sensitive to the application of an external stimulus including the step of producing, through the application of the external stimulus, the permeabilization of at least a selected first particle, consisting in the organization of the first particles through a first force field, to generate a second force field substantially placed in proximity of at least a selected first particle to be permeabilized. | 03-18-2010 |
20100196984 | CONTROLLED ELECTROPORATION AND MASS TRANSFER ACROSS CELL MEMBRANES - Electroporation is performed in a controlled manner in either individual or multiple biological cells or biological tissue by monitoring the electrical impedance, defined herein as the ratio of current to voltage in the electroporation cell. The impedance detects the onset of electroporation in the biological cell(s), and this information is used to control the intensity and duration of the voltage to assure that electroporation has occurred without destroying the cell(s). This is applicable to electroporation, in general. In addition, a particular method and apparatus are disclosed in which electroporation and/or mass transfer across a cell membrane are accomplished by securing a cell across an opening in a barrier between two chambers such that the cell closes the opening. The barrier is either electrically insulating, impermeable to the solute, or both, depending on whether pore formation, diffusive transport of the solute across the membrane, or both are sought. Electroporation is achieved by applying a voltage between the two chambers, and diffusive transport is achieved either by a difference in solute concentration between the liquids surrounding the cell and the cell interior or by a differential in concentration between the two chambers themselves. Electric current and diffusive transport are restricted to a flow path that passes through the opening. | 08-05-2010 |
20110143415 | REPROGRAMMING NORMAL AND CANCEROUS HUMAN CELL LINES INTO HUMAN INDUCED POLURIPOTENT STEM CELLS BY CO-ELECTROPORATION WITH LIVING XENOPUS LAEVIS FROG OOCYTES - Using electroporation, it is possible to activate the natural reprogramming potential of living | 06-16-2011 |
20110229952 | METHOD AND APPARATUS FOR AVALANCHE-MEDIATED TRANSFER OF AGENTS INTO CELLS - The present invention provides a method and apparatus for transferring an agent into a cell. The method includes the steps of providing an agent outside of a cell and generating a vapor bubble and a plasma discharge between an avalanche electrode and a conductive fluid surrounding the cell. The vapor bubble and plasma discharge generate a mechanical stress wave and an electric field, respectively. The combination of this mechanical stress wave and electric field results in permeabilization of the cell, which in turn results in transfer of the agent into the cell. | 09-22-2011 |
20120040428 | PROCEDURE FOR EXTRACTING OF LIPIDS FROM ALGAE WITHOUT CELL SACRIFICE - A system and method are disclosed for extracting lipids from algal cells. In the method, lipids are extracted from algal cells by exposing the algal cells in an aqueous medium to an electric field sufficient to cause release of lipids from said cells. In the system, an electric field is formed between two electrodes connected with an electrical power supply and configured such that during use an aqueous medium containing the algal cells passes between the electrodes to extract lipids therefrom. | 02-16-2012 |
20120064594 | DEVICE AND METHOD FOR TREATING CELLS - The present invention relates to a device for treating biological cells in an object, the device comprising: —a single winding coil element; —an electrical generator connected to the single winding coil element, the single winding being configured to be positioned essentially around the object; wherein the electrical generator is configured to discharge into the single winding coil element so that the single winding coil element generates a short duration pulsed electromagnetic field by magnetic induction in the single winding coil element, the electromagnetic field having a field strength that is sufficiently high to affect, preferably increase the permeability of cell membranes and/or intracellular membranes of the biological cells contained in the object when in operation the object is placed inside the single winding coil element. | 03-15-2012 |
20120107896 | Method for Treating a Biological Material Comprising Living Cells - A plasma containing at least one reactive species are used to deliver agents into living cells or an extracellular matrix of the living cells. The method and system allows for treatment of the living cells without causing irreversible damage to the cell membranes of the living cells. The plasma is produced by dielectric barrier discharge. | 05-03-2012 |
20120107897 | DOUBLE-STRANDED OLIGONUCLEOTIDES - Antisense sequences, including duplex RNAi compositions, which possess improved properties over those taught in the prior art are disclosed. The invention provides optimized antisense oligomer compositions and method for making and using the both in in vitro systems and therapeutically. The invention also provides methods of making and using the improved antisense oligomer compositions. | 05-03-2012 |
20120231517 | MINIATURIZED ELECTROPORATION-READY MICROWELL ARAY FOR HIGH-THROUGHPUT GENOMIC SCREENING - Methods of introducing exogenous molecules into cells including cell lines and primary cells are provided. Additionally, miniaturized electroporation-ready microwell arrays are provided. These tools provide a miniaturized high-throughput functional genomics screening platform to carry out genome-size screens in a variety of cell types. | 09-13-2012 |
20120244593 | METHOD, DEVICE AND APPARATUS FOR INDUCING SELF-ADJUSTING CELL ELECTROPORATION - The invention provides methods, devices and apparatuses for providing cell electroporation. In accordance with an aspect of the invention, self-adjusting cell electroporation may be provided. A cell transfection apparatus may be provided. The cell transfection apparatus may include a plate comprising a plurality of chambers configured to receive and confine a population of host cells. The cell transfection apparatus may also include a plurality of electrodes configured to be in electrical communication with a corresponding chamber of said plate. A predetermined electrical current may be directed through a chamber to effect transfection of said host cells. | 09-27-2012 |
20120264187 | REACTOR SYSTEM FOR ELECTROPORATION - The invention relates to a reactor system, comprising: —a reactor chamber having a length and a width, whereby the reactor chamber contains a central section along its length; —a first pulse generator to which two electrodes A1 and A2 are connected, whereby the electrodes A1 and A2 are located in the reactor chamber in the central section and such that they are, when measured in the length direction, at least a distance equalling half the width of the reactor chamber apart; —a second pulse generator to which two electrodes B1 and B2 are connected, whereby the electrodes B1 and B2 are located in the reactor chamber in the central section and such that they are, when measured in the length direction, at least a distance equalling half the width of the reactor chamber apart. | 10-18-2012 |
20130023023 | ANTI-CANCER AGENT - Disclosed is a | 01-24-2013 |
20130045520 | Double-stranded oligonucleotides - Antisense sequences, including duplex RNAi compositions, which possess improved properties over those taught in the prior art are disclosed. The invention provides optimized antisense oligomer compositions and method for making and using the both in in vitro systems and therapeutically. The invention also provides methods of making and using the improved antisense oligomer compositions. | 02-21-2013 |
20130260434 | METHOD AND ELECTRODE ASSEMBLY FOR TREATING ADHERENT CELLS - The invention relates to an electrode assembly | 10-03-2013 |
20130260435 | ELECTROPORATION-INDUCED ELECTROSENSITIZATION - Methods of enhancing membrane permeabilization in a cell are provided. A method includes disposing the cell between a first electrode and a second electrode and applying a plurality of electrical pulses between the first electrode and the second electrode. In the method, the plurality of electrical pulses include at least two trains of pulses separated by an interval greater than about 10 s. Further, the amplitude of the electrical pulses is selected to be greater than about 0.2 kV/cm. | 10-03-2013 |
20140073027 | MICROFLUIDIC PHOTOPORATION - A cell permeabilizing micro fluidic system for permeabilizing one or more cells in a fluid flow. The system has a micro fluidic channel for channeling at least one cell in a fluid flow and an optical source for generating a beam of light for permeabilizing the at least one cell, wherein the channel and the source are arranged so that the light beam and fluid flow are collinear in a permeabilization part of the channel and cells are permeabilized within the permeabilization part. | 03-13-2014 |
20140106429 | METHODS AND COMPOSITIONS FOR HIGH EFFICIENCY TRANSFECTION OF siRNA - Described herein are methods and compositions for high efficiency transfection of siRNA into a cell population. Such methods and compositions utilize a low voltage pre-conditioning pulse to modulate the efficiency of siRNA transfection. In some embodiments, the methods and compositions permit spatial and temporal control of siRNA transfection efficiency within a population of cells. The disclosed methods and compositions, in some embodiments, are amenable to high throughput applications such as siRNA library-based phenotypic screening. | 04-17-2014 |
20140302579 | DEVICE COMPRISING A COMPOSITE MATERIAL AND HAVING NANOTUBES THAT ARE SUBJECTED TO AN ELECTRIC FIELD, AND USES THEREOF - The present invention concerns a device comprising (i) a composite material comprising (1) a plurality of conductive or semiconductive nanotubes, and (2) a matrix arranged between these nanotubes and (ii) means allowing said composite material to be subjected to an electric field. The present invention also concerns the uses of said device in particular to defoul or to modify a composite material and to electroporate at least one cell. | 10-09-2014 |
20150044750 | MICROFLUIDIC VORTEX-ASSISTED ELECTROPORATION SYSTEM AND METHOD - A system and method include delivering cells of interest to multiple traps via a channel connecting the traps, maintaining a vortex flow in the traps to trap the cells of interest in the traps, providing first molecules of interest to the traps, and providing an electric field across the traps to perform electroporation of the first molecules of interest into the cells of interest in the traps. | 02-12-2015 |
20150044751 | PHOTOTHERMAL SUBSTRATES FOR SELECTIVE TRANSFECTION OF CELLS - This invention provides novel tools for surgery on single cells and substrates/devices for delivery of reagents to selected cells. In certain embodiments the substrates comprise a surface comprising one or more orifices, where nanoparticles and/or a thin film is deposited on a surface of said orifice or near said orifice, where the nanoparticles and/or a thin film are formed of materials that heat up when contacted with electromagnetic radiation. In certain embodiments the pores are in fluid communication with microchannels containing one or more reagents to be delivered into the cells. | 02-12-2015 |
20160022989 | ELECTRO-STIMULATION DEVICE AND METHOD OF SYSTEMATICALLY COMPOUNDED MODULATION OF CURRENT INTENSITY WITH OTHER OUTPUT PARAMETERS FOR AFFECTING BIOLOGICAL TISSUES - A non-user controllable electro-therapy device has a housing for a microprocessor, power source, status indicator, activation switch, and one or more channels for electrode contact. Only the activation switch is user-accessible. The microprocessor generates a non-user controllable frequency dependent mixed electrical signal through the electrodes, wherein the mixed electrical signal is a combination of at least two different frequencies, a first frequency having a first minimum and maximum microamp range and a second frequency having a different second minimum and maximum microamp range. The higher of the two frequencies is superimposed on the lower frequency, creating a current intensity window as an envelope along a profile of the lower frequency. The mixed electrical signal is automatically applied for a pre-determined period of time, and amplitude and/or duration and/or frequencies is varied according to a pre-set schedule programmed into a controller coupled to the one or more electrodes. | 01-28-2016 |
20160108433 | SYSTEMS, APPARATUS, AND METHODS FOR DROPLET-BASED MICROFLUIDICS CELL PORATION - The present disclosure provides systems, apparatus, and methods that include an electrowetting-on-dielectric microfluidic apparatus for effecting poration of cells in a droplet. | 04-21-2016 |
20170233715 | DEVICE AND METHOD FOR LARGE VOLUME TRANSFECTION | 08-17-2017 |
20170233716 | DEVICE AND METHOD FOR LARGE VOLUME TRANSFECTION | 08-17-2017 |
20190144844 | DEVICE AND METHOD FOR LARGE VOLUME TRANSFECTION | 05-16-2019 |