Class / Patent application number | Description | Number of patent applications / Date published |
435148000 | Ketone | 78 |
20080220487 | Molecular design of thermostable alcohol dehydrogenase for synthesis for chiral aromatic alcohols - The present invention relates to compositions and methods utilizing thermostable and novel alcohol dehydrogenase enzymes for biosynthesizing chiral specific molecules for use as precursor molecules in synthesizing pharmaceutical compounds. Particularly, in preferred embodiments, the invention relates to directed engineering of an enzymatic catalytic site of an alcohol dehydrogenase enzyme gene for enhancing enantioselectivity for (S)-enantiomer substrate catalytic activity for providing aryl (S)-enantiomer products in stereomeric excess. | 09-11-2008 |
20080233622 | NOVEL METHODS FOR PRODUCTION OF 5-EPI-BETA-VETIVONE, 2-ISOPROPYL-6,10-DIMETHYL-SPIRO[4.5]DECA-2,6-DIEN-8-ONE, AND 2-ISOPROPYL-6,10-DIMETHYL-SPIRO[4.5]DECA-1,6-DIEN-8-ONE - The present invention is directed to novel methods for production of 5-epi-β-vetivone, 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-2,6-dien-8-one and 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-1,6-dien-8-one, which are useful for their fragrant qualities. In one embodiment the present invention describes a method for production of 5-epi-β-vetivone by the use of premnaspirodiene as starting material. In another embodiment the present invention describes a method for production of 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-2,6-dien-8-one and 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-1,6-dien-8-one by the use of premnaspirodiene as starting material. In yet another embodiment the present invention describes a novel method for production of premnaspirodiene from a terpene substrate. | 09-25-2008 |
20080261286 | Methods for producing optically active alpha-hydroxy amides - An objective of the present invention is to provide efficient methods for producing (R)-2-chloromandelamide with high optical purity. Another objective of the present invention is to provide novel methods for producing α-ketoamide reductases that reduce 2-chlorobenzoyl formamide to (R)-2-chloromandelamide with high optical purity, using NADPH as the coenzyme. | 10-23-2008 |
20080274522 | METHOD FOR THE PRODUCTION OF 2-BUTANONE - A method for the production of 2-butanone by fermentation using a microbial production host is disclosed. The method employs a reduction in temperature during the fermentation process that results in a more robust tolerance of the production host to the butanone product. | 11-06-2008 |
20090130730 | YEAST FOR EXTRACTION OF LIPID-SOLUBLE COMPONENT, METHOD FOR PRODUCING THE SAME, COLOR-IMPROVING AGENT USING THE SAME AND METHOD FOR PRODUCING LIPID-SOLUBLE COMPONENT - The production process for yeast for fat-soluble component extraction according to the invention comprises a breeding step wherein yeast having fat-soluble components to be extracted are bred, in such a manner that the pH of the medium decreases as growth proceeds, until falling below the limit of the breedable pH range. | 05-21-2009 |
20090162911 | STRAIN FOR BUTANOL PRODUCTION - Using screening of transposon random insertion mutants, genes involved in a complex that is a three-component proton motive force-dependent multidrug efflux system were found to be involved in | 06-25-2009 |
20090191604 | METHOD FOR OBTAINING NATURAL ASTAXANTHIN FROM EGGS AND GONADS OF SNAILS - The present invention relates to a process which can effectively extract and purify natural astaxanthin from the eggs and gonads of snails. | 07-30-2009 |
20090221046 | BIOCATALYTIC RACEMISATION OF ALPHA-HYDROXYKETONES - A process for the racemisation of an optically active alpha-hydroxyketone by incubating said alpha-hydroxyketone in the presence of an acetoin racemase of | 09-03-2009 |
20090298146 | Method of Producing Astaxanthin or Metabolic Product Thereof by Using Carotenoid Ketolase and Carotenoid Hydroxylase Genes - To provide a microorganism or a plant transformed with a β-ionone ring-4-ketolase gene and/or β-ionone ring-3-hydroxylase gene derived from | 12-03-2009 |
20090298147 | Method of Making (+)- Sitophilure - (+)-Sitophilure, the aggregation pheromone of the pests rice weevil and maize weevil, is synthesized in high yield and diastereomeric excess by contacting 4-methyl-3,5heptadione with a reduced nicotinamide cofactor and a ketoreductase enzyme capable of catalyzing the reduction of 4-methyl-3,5-heptadione to produce (4R,5S)-5-hydroxy-4-methyl-3-heptanone to the substantial exclusion of other diastereomers. | 12-03-2009 |
20090311761 | Process for Synthesis of (3S)- and (3R)-3-Hydroxy-Beta-Ionone, and Their Transformation to Zeaxanthin and Beta-Cryptoxanthin - (3R)-3-Hydroxy-β-ionone and (3S)-3-hydroxy-β-ionone are two important intermediates in the synthesis of carotenoids with β-end group such as lutein, zeaxanthin, β-cryptoxanthin, and their stereoisomers. Among the various stereoisomers of these carotenoids, only (3R,3′R,6′R)-lutein, (3R,3′R)-zeaxanthin, and (3R)-β-cryptoxanthin are present in commonly consumed fruits and vegetables. There are 3 possible stereoisomers for zeaxanthin, these are: dietary (3R,3′R)-zeaxanthin (1), non-dietary (3S,3′S)-zeaxanthin (2), and non-dietary (3R,3′S;meso)-zeaxanthin (3) which is a presumed metabolite of dietary lutein. Dietary lutein as well as 1 and 3 are accumulated in the human macula and have been implicated in the prevention of age-related macular degeneration. (3R)-β-Cryptoxanthin (4) is also present in selected ocular tissues at a very low concentration whereas its enantiomer (3S)-β-cryptoxanthin (5) is absent in foods and human plasma. | 12-17-2009 |
20100009421 | Method For The Enzymatic Reduction Of Alkyne Derivates - The invention relates to a method for the enzymatic reduction of alkyne derivatives of the formula (1), | 01-14-2010 |
20100035315 | PROCESS FOR ENZYMATIC REDUCTION OF ALKENE DERIVATIVES - A method for enzymatic preparation of compounds of the general formula (2) from unsaturated alkene derivatives of the general formula (1) by reducing a compound of the formula (1) in the presence of a reductase, comprising at least one of the polypeptide sequences SEQ ID NO: 1, 2 or 3 or having a functionally equivalent polypeptide sequence which is at least 80% identical to SEQ ID NO: 1, 2 or 3. | 02-11-2010 |
20100184173 | MICROORGANISMS FOR THE PRODUCTION OF METHYL ETHYL KETONE AND 2-BUTANOL - A non-naturally occurring microbial organism having a methyl ethyl ketone pathway includes at least one exogenous nucleic acid encoding a methyl ethyl ketone pathway enzyme expressed in a sufficient amount to produce methyl ethyl ketone. The methyl ethyl ketone pathway includes a β-ketothiolase, a β-ketovalerate decarboxylase and an enzyme selected from the group consisting of a β-ketovaleryl-CoA hydrolase and a β-ketovaleryl-CoA transferase. Alternatively, the methyl ethyl ketone pathway includes a 2-methylacetoacetyl-CoA thiolase, a 2-methylacetoacetate decarboxylase and an enzyme selected from the group consisting of a 2-methylacetoacetyl-CoA hydrolase and a 2-methylacetoacetyl-CoA transferase. Either pathway can further include a methyl ethyl ketone reductase to produce 2-BuOH. A method for producing methyl ethyl ketone or 2-BuOH includes culturing these non-naturally occurring microbial organisms under conditions, and for a sufficient period of time, to produce methyl ethyl ketone or 2-BuOH. | 07-22-2010 |
20100184174 | PROCESS FOR THE OXIDATIVE CLEAVAGE OF VINYLAROMATICS USING PEROXIDASES OR LACCASES - The invention relates to a method for the oxidative cleavage of vinyl aromatics of the formula (1) characterized in that (a) compound(s) of the formula (1) is/are oxidized to aldehydes and ketones of the formulas (2) and (3), respectively, in the presence of molecular oxygen using at least one enzyme selected from peroxidases and laccases as a catalyst, according to the following general reaction scheme: | 07-22-2010 |
20100190225 | D-PSICOSE PRODUCTION METHOD BY D-PSICOSE EPIMERASE - Provided is a method of producing D-psicose using a D-psicose epimerase derived from | 07-29-2010 |
20100279369 | METABOLICALLY ENGINEERED MICROORGANISM USEFUL FOR THE PRODUCTION OF ACETOL - This invention concerns a microorganism useful for the production of acetol from a simple carbon source, wherein said microorganism is characterized by:
| 11-04-2010 |
20110008858 | MICROORGANISMS AND METHODS FOR CARBON-EFFICIENT BIOSYNTHESIS OF MEK AND 2-BUTANOL - A non-naturally occurring microbial organism has at least one exogenous nucleic acid encoding a MEK pathway enzyme expressed in a sufficient amount to produce MEK. The MEK pathway includes an enzyme selected from an acetoacetyl-CoA dehydrogenase (bifunctional), an acetoacetyl-CoA aldehyde dehydrogenase, a 3-oxobutyraldehyde reductase, a 3-oxobutanol dehydratase, an MEK oxidoreductase, a 3-oxobutyraldehyde aminotransferase, a 4-aminobutan-2-one deaminase, a 2-amino-4-ketopentanoate (AKP) thiolase, an AKP aminotransferase, a 2,4-dioxopentanoate decarboxylase, an AKP deaminase, an acetylacrylate decarboxylase, an AKP decarboxylase, a glutamate dehydrogenase, a 3-oxobutyraldehyde oxidoreductase (aminating) and an AKP oxidoreductase (aminating). A 2-butanol pathway further includes an MEK reductase. A method for producing MEK or 2-butanol includes culturing these organisms under conditions and for a sufficient period of time to produce MEK or 2-butanol. | 01-13-2011 |
20110014668 | ORGANISMS FOR THE PRODUCTION OF CYCLOHEXANONE - A non-naturally occurring microbial organism has cyclohexanone pathways that include at least one exogenous nucleic acid encoding a cyclohexanone pathway enzyme. A pathway includes a 2-ketocyclohexane-1-carboxyl-CoA hydrolase (acting on C—C bond), a 2-ketocyclohexane-1-carboxylate decarboxylase and an enzyme selected from a 2-ketocyclohexane-1-carboxyl-CoA hydrolase (acting on thioester), a 2-ketocyclohexane-1-carboxyl-CoA transferase, and a 2-ketocyclohexane-1-carboxyl-CoA synthetase. A pathway includes an enzyme selected from a 6-ketocyclohex-1-ene-1-carboxyl-CoA hydrolase (acting on C—C bond), a 6-ketocyclohex-1-ene-1-carboxyl-CoA synthetase, a 6-ketocyclohex-1-ene-1-carboxyl-CoA hydrolase (acting on thioester), a 6-ketocyclohex-1-ene-1-carboxyl-CoA transferase, a 6-ketocyclohex-1-ene-1-carboxyl-CoA reductase, a 6-ketocyclohex-1-ene-1-carboxylate decarboxylase, a 6-ketocyclohex-1-ene-1-carboxylate reductase, a 2-ketocyclohexane-1-carboxyl-CoA synthetase, a 2-ketocyclohexane-1-carboxyl-CoA transferase, a 2-ketocyclohexane-1-carboxyl-CoA hydrolase (acting on thioester), a 2-ketocyclohexane-1-carboxylate decarboxylase, and a cyclohexanone dehydrogenase. A pathway includes an adipate semialdehyde dehydratase, a cyclohexane-1,2-diol dehydrogenase, and a cyclohexane-1,2-diol dehydratase. A pathway includes a 3-oxopimelate decarboxylase, a 4-acetylbutyrate dehydratase, a 3-hydroxycyclohexanone dehydrogenase, a 2-cyclohexenone hydratase, a cyclohexanone dehydrogenase and an enzyme selected from a 3-oxopimeloyl-CoA synthetase, a 3-oxopimeloyl-CoA hydrolase (acting on thioester), and a 3-oxopimeloyl-coA transferase. Each these pathways can include a PEP carboxykinase. A method for producing cyclohexanone includes culturing these non-naturally occurring microbial organisms. | 01-20-2011 |
20110027844 | METHOD FOR PRODUCING QUINONES - A method for conveniently and efficiently producing quinones, and particularly menaquinone, from a microorganism is provided. The present invention relates to a method for producing quinones, comprising culturing a microorganism that produces quinones in the presence of a porous carrier. | 02-03-2011 |
20110091948 | MICROORGANISM CAPABLE OF PRODUCING IMPROVED POLYHYDROXYALKANOATE AND METHOD OF PRODUCING POLYHYDROXYALKANOATE BY USING THE SAME - The present invention relates to a microorganism which is capable of producing a polyhydroxyalkanoate (PHA) and satisfies the requirements: (1) expression of a phbA gene is repressed or a catalytic activity of an enzyme encoded by the gene is repressed; (2) expression of a bktB gene is enhanced or a catalytic activity of an enzyme encoded by the gene is increased; and (3) a polyhydroxyalkanoate synthase gene and a crotonyl-CoA reductase gene are introduced thereinto. Culture of this microorganism enables efficient production of P(3HB-co-3HH), which is a PHA having excellent flexibility and being applied to a variety of applications, with an inexpensive carbon source. | 04-21-2011 |
20110143406 | Novel (S,S) -Butanediol Dehydrogenase, Gene for the Same, and Use of the Same - The present invention has its object to provide a novel (S,S)-butanediol dehydrogenase. The present invention also has its object to provide a gene coding for the enzyme protein, a vector containing the gene, a transformant harboring the vector, and a method of producing an optically active alcohol using the transformant. The polypeptide according to one embodiment of the present invention has the physicochemical properties including actions such as: acting on (2S,3S)-2,3-butanediol to form (S)-acetoin in the presence of NAD | 06-16-2011 |
20110201070 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 1,2-PROPANEDIOL AND ACETOL - The present invention concerns a modified microorganism with an increased methylglyoxal reductase activity, and its use for the preparation of 1,2-propanediol and/or acetol. In particular this increased methylglyoxal reductase activity is obtained by increasing the expression of specific genes from microorganisms. | 08-18-2011 |
20110207187 | BACTERIUM PRODUCING 2-DEOXY-SCYLLO-INOSOSE (DOI) AND METHOD OF PRODUCING 2-DEOXY-SCYLLO-INOSOSE (DOI) BY USING SAME - Disclosed is an | 08-25-2011 |
20110262980 | MICRO-ORGANISMS FOR THE PRODUCTION OF ACETOL OBTAINED BY A COMBINATION OF EVOLUTION AND RATIONAL DESIGN - The present invention concerns a new method combining evolution and rational design for the preparation of a strain of micro-organism for the production of acetol from a simple carbon source. The said method comprises:
| 10-27-2011 |
20110262981 | CAROTENOID FERMENTATION METHOD - The present invention provides a method for producing a carotenoid, which comprises culturing a carotenoid-producing bacterium in an amino acid-supplemented medium, and collecting the carotenoid from the resulting cultured product, wherein the amino acid is at least one selected, from the group consisting of glutamic acid, aspartic acid, glutamine, asparagine, alanine, glycine, serine, threonine, arginine, tyrosine, proline, phenylalanine and leucine, and salts thereof | 10-27-2011 |
20110275128 | Use Of Whey For The Manufacture Of Erythritol - Erythritol is prepared from whey. Whey is treated to form lactose, the lactose is treated to form glucose and galactose, the glucose and galactose are separated, and then the glucose is treated to form erythritol. | 11-10-2011 |
20120045806 | ENZYMATIC SYNTHESIS OF NOOTKATONE - Polypeptide with an amino acid sequence according to SEQ ID No. 1 or a variant in which up to 10% of the amino acids have been altered by insertions, deletions or substitution. | 02-23-2012 |
20120045807 | PROCESS FOR PRODUCING CHEMICALS USING MICROBIAL FERMENTATION OF SUBSTRATES COMPRISING CARBON MONOXIDE - A process for converting a substrate such as carbon monoxide to useful chemicals has been developed. The process involves providing a substrate comprising CO to a bioreactor which contains a culture of one or more micro-organisms and anaerobically fermenting the substrate to produce 2,3-butanediol (BDO). The BDO is next converted to one or more of butane, butadiene and/or methyl ethyl ketone which in turn can be converted to other compounds. The source of the CO can be an industrial process such as the ferrous metal products manufacturing. The microorganism can be | 02-23-2012 |
20120100583 | Enzymatic Synthesis of Polymers - The invention relates to new methods of enzymatic synthesis of polymers such as polyorganosilicones and polyesters, and new polymers made by these methods. | 04-26-2012 |
20120100584 | 2-deoxy-scyllo-inosose synthase - An object of the present invention is to provide a DOI synthase having properties such as stability to heat and pH, which are superior to those of conventional enzymes, and a method for producing DOI using the above-mentioned enzyme. The present invention provides a 2-deoxy-scyllo-inosose synthase having the properties described in the following (1), (2), (4), (6) and (7), and also having the properties described in the following (3) and/or (5):
| 04-26-2012 |
20120122169 | MUTANT YQHD ENZYME FOR THE PRODUCTION OF A BIOCHEMICAL BY FERMENTATION - The present invention concerns a method for the production of a biochemical selected among acetol and 1,2-propanediol, 1,3-propanediol, ethylene glycol and 1,4-butanediol comprising culturing a microorganism modified for an improved production of the biochemical selected among acetol and 1,2-propanediol, 1,3-propanediol, ethylene glycol and 1,4-butanediol in an appropriate culture medium and recovery of the desired biochemical which may be further purified wherein the microorganism expresses a YqhD enzyme which catalytic efficiency toward NADPH is increased. | 05-17-2012 |
20120196340 | Novel Sesquiterpene Synthase Gene and Protein - The invention relates to sesquiterpene synthases and methods for their production and use. Particularly, the invention provides nucleic acids comprising the nucleotide sequence of citrus valencene synthase (CVS) which codes for at least one CVS. The invention further provides nucleic acids comprising the nucleotide sequence coding for amino acid residues forming the tier 1 and tier 2 domains of CVS. The invention also provides for methods of making and using the nucleic acids and amino acids of the current invention. | 08-02-2012 |
20120295318 | CYCLOPROPENONES AND THE PHOTOCHEMICAL GENERATION OF CYCLIC ALKYNES THEREFROM - Cyclic alkynes (e.g., cyclooctynes such as dibenzocyclooctynes) can be photochemically generated from cyclopropenones as disclosed herein. The cyclic alkynes can be reacted (e.g., in situ) with materials having alkyne-reactive groups (e.g., azide groups in a “click” reaction). In preferred embodiments, the generation and reaction of the cyclic alkyne can proceed in the absence of a catalyst (e.g., Cu(I)). These reactions can be useful, for example, for the selective labeling of living cells that are metabolically modified with azido-containing surface monosaccharides, or for light-directed surface patterning. | 11-22-2012 |
20120329111 | Microorganisms for Producing Cyclohexanone and Methods Related Thereto - Provided herein is a non-naturally occurring microbial organism having a cyclohexanone pathway and comprising at least one exogenous nucleic acid encoding a cyclohexanone pathway enzyme. Also provided herein is a method for producing cyclohexanone, including culturing these non-naturally occurring microbial organisms. | 12-27-2012 |
20130122560 | Novel fragrance and methods for production fo 5-epi- -vetivone, 2-isopropyl-6, 10-dimethyl-spiro[4.5]deca-2,6-dien-8-one, and 2-isopropyl-6, 10-dimethyl-spiro[4.5]deca-1, 6-dien-8-one - The present invention is directed to novel methods for production of 5-epi-β-vetivone, 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-2,6-dien-8-one and 2-isopropyl-6,10-dimethylspiro[4.5]deca-1,6-dien-8-one, which are useful for their fragrant qualities. Provided are methods for production of premnaspirodiene from a terpene substrate, methods for production of 5-epi-β-vetivone from premnaspirodiene as starting material, and methods for production of 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-2,6-dien-8-one and 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-1,6-dien-8-one from premnaspirodiene as starting material. | 05-16-2013 |
20130164803 | CYCLOPROPENONES AND THE PHOTOCHEMICAL GENERATION OF CYCLIC ALKYNES THEREFROM - Cyclic alkynes (e.g., cyclooctynes such as dibenzocyclooctynes) can be photochemically generated from cyclopropenones as disclosed herein. The cyclic alkynes can be reacted (e.g., in situ) with materials having alkyne-reactive groups (e.g., azide groups in a “click” reaction). In preferred embodiments, the generation and reaction of the cyclic alkyne can proceed in the absence of a catalyst (e.g., Cu(I)). These reactions can be useful, for example, for the selective labeling of living cells that are metabolically modified with azido-containing surface monosaccharides, or for light-directed surface patterning. | 06-27-2013 |
20130177953 | RECOMBINANT PROCESS FOR THE PRODUCTION OF R-AROMATIC ALPHA HYDROXY KETONES - A process for preparation of (R)-aromatic α-hydroxy ketones of formula (I), said process occurring in strain(s) of yeast expressing a recombinant pyruvate decarboxylase, having cysteine residues at positions 221 and 222 of PDC1, an isoenzyme of said pyruvate decarboxylase, substituted with glutamate and alanine respectively such that the said mutation being in the regulatory site of pyruvate decarboxylase, selectively favours carboligation reaction over decarboxylation. | 07-11-2013 |
20130316414 | ENHANCED PYRUVATE TO 2,3-BUTANEDIOL CONVERSION IN LACTIC ACID BACTERIA - A high flux of metabolites from pyruvate to 2,3-butanediol in | 11-28-2013 |
20140045233 | Method for Biotechnological Production of Dihydrochalcones - A method for production of a dihydrochalcone, especially of phloretin, using a transgenic microorganism, containing a nucleic acid section (a), comprising or consisting of a gene coding for a bacterial chalcone isomerase, and/or a nucleic acid section (a′), comprising or consisting of a gene coding for a plant chalcone isomerase, and a nucleic acid section (b), comprising or consisting of a gene coding for a bacterial enoate reductase, corresponding transgenic microorganisms, containing a nucleic acid section (a), comprising or consisting of a gene coding for a bacterial chalcone isomerase, and/or a nucleic acid section (a′), comprising or consisting of a gene coding for a plant chalcone isomerase, and/or a nucleic acid section (b), comprising or consisting of a gene coding for a bacterial enoate reductase, and host cells, containing one or more identical or different such vectors. | 02-13-2014 |
20140206050 | 2-Deoxy-Scyllo-Inosose Synthase - An object of the present invention is to provide a DOI synthase having properties such as stability to heat and pH, which are superior to those of conventional enzymes, and a method for producing DOI using the above-mentioned enzyme. The present invention provides a 2-deoxy-scyllo-inosose synthase having the properties described in the following (1), (2), (4), (6) and (7), and also having the properties described in the following (3) and/or (5): | 07-24-2014 |
20140356919 | ORGANISMS FOR THE PRODUCTION OF CYCLOHEXANONE - A non-naturally occurring microbial organism has cyclohexanone pathways that include at least one exogenous nucleic acid encoding a cyclohexanone pathway enzyme. A pathway includes a 2-ketocyclohexane-1-carboxyl-CoA hydrolase (acting on C—C bond), a 2-ketocyclohexane-1-carboxylate decarboxylase and an enzyme selected from a 2-ketocyclohexane-1-carboxyl-CoA hydrolase (acting on thioester), a 2-ketocyclohexane-1-carboxyl-CoA transferase, and a 2-ketocyclohexane-1-carboxyl-CoA synthetase. A pathway includes an enzyme selected from a 6-ketocyclohex-1-ene-1-carboxyl-CoA hydrolase (acting on C—C bond), a 6-ketocyclohex-1-ene-1-carboxyl-CoA synthetase, a 6-ketocyclohex-1-ene-1-carboxyl-CoA hydrolase (acting on thioester), a 6-ketocyclohex-1-ene-1-carboxyl-CoA transferase, a 6-ketocyclohex-1-ene-1-carboxyl-CoA reductase, a 6-ketocyclohex-1-ene-1-carboxylate decarboxylase, a 6-ketocyclohex-1-ene-1-carboxylate reductase, a 2-ketocyclohexane-1-carboxyl-CoA synthetase, a 2-ketocyclohexane-1-carboxyl-CoA transferase, a 2-ketocyclohexane-1-carboxyl-CoA hydrolase (acting on thioester), a 2-ketocyclohexane-1-carboxylate decarboxylase, and a cyclohexanone dehydrogenase. A pathway includes an adipate semialdehyde dehydratase, a cyclohexane-1,2-diol dehydrogenase, and a cyclohexane-1,2-diol dehydratase. A pathway includes a 3-oxopimelate decarboxylase, a 4-acetylbutyrate dehydratase, a 3-hydroxycyclohexanone dehydrogenase, a 2-cyclohexenone hydratase, a cyclohexanone dehydrogenase and an enzyme selected from a 3-oxopimeloyl-CoA synthetase, a 3-oxopimeloyl-CoA hydrolase (acting on thioester), and a 3-oxopimeloyl-coA transferase. Each these pathways can include a PEP carboxykinase. A method for producing cyclohexanone includes culturing these non-naturally occurring microbial organisms. | 12-04-2014 |
20140370560 | BACTERIAL PRODUCTION OF METHYL KETONES - The present invention relates to methods and compositions for increasing production of methyl ketones in a genetically modified host cell that overproduces β-ketoacyl-CoAs through a re-engineered β-oxidation pathway and overexpresses FadM. | 12-18-2014 |
20150079649 | VALENCENE SYNTHASE - The present invention relates to a novel valencene synthase, to a nucleic acid encoding such valencene synthase, to a host cell comprising said encoding nucleic acid sequence and to a method for preparing valencene, comprising converting farnesyl diphosphate to valencene in the presence of a valencene synthase according to the invention. | 03-19-2015 |
20150093796 | CLOSTRIDIUM ACETOBUTYLICUM AND APPLICATION THEREOF - The present invention provides | 04-02-2015 |
20150315613 | ENONE REDUCTASES - The disclosure relates to engineered enone reductase polypeptides having improved properties, polynucleotides encoding the engineered polypeptides, related vectors, host cells, and methods for making the engineered enone reductase polypeptides. The disclosure also provides methods of using the engineered enone reductase polypeptides for chemical transformations. | 11-05-2015 |
20160121236 | METHODS AND SYSTEMS FOR REDUCING THE LEVEL OF ONE OR MORE IMPURITIES THAT ARE PRESENT IN A PRETREATED CELLULOSIC MATERIAL AND/OR DISTILLATE - The present invention relates to methods and systems for remediating one or more impurities (e.g., diacetyl) that are present in manufacturing an alcohol (e.g., ethanol) from cellulosic biomass. The methods and systems include reacting the one or more impurities with at least one treatment compound (e.g., an oxidizing agent, an alkali compound, or a mixture thereof) to form a reaction product that can be separated from the alcohol. | 05-05-2016 |
20160138053 | PRODUCTION METHOD FOR TAGATOSE - A method for producing tagatose comprises: a) performing epimerization of fructose using hexuronate C4-epimerase to obtain an epimerized product comprising tagatose; b) purifying the epimerized product; and c) crystallizing the purified epimerized product. The hexuronate C4-epimerase is an enzyme derived from | 05-19-2016 |
20160152907 | METHODS TO PRODUCE FUELS | 06-02-2016 |
20160186162 | ALDOLASE, ALDOLASE MUTANT, AND METHOD AND COMPOSITION FOR PRODUCING TAGATOSE BY USING SAME - This disclosure relates to aldolase, an aldolase mutant, and a method and a composition for producing tagatose by using the same. The feature of the disclosure is environment-friendly due to the use of an enzyme acquired from microorganisms, requires only a simple process of enzyme immobilization, uses a low-cost substrate in a substrate compared with a conventional method for producing tagatose and has a remarkably high yield, thereby greatly reducing production costs and maximizing production effects. | 06-30-2016 |
20160251281 | METHOD OF RECOVERING 1,3-BUTADIENE AND METHYLETHYLKETONE FROM DEHYDRATION PRODUCTS OF 2,3-BUTANEDIOL | 09-01-2016 |
20180023073 | ALDOLASE, ALDOLASE MUTANT, AND METHOD AND COMPOSITION FOR PRODUCING TAGATOSE BY USING SAME | 01-25-2018 |
435149000 | Cyclopentanone or cyclopentadione containing compound | 2 |
20110020887 | PROCESS FOR THE ENANTIOSELECTIVE ENZYMATIC REDUCTION OF SECODIONE DERIVATIVES - The invention relates to a process for the enantioselective enzymatic reduction of secodione derivatives. | 01-27-2011 |
20120040424 | PROCESS FOR THE ENANTIOSELECTIVE ENZYMATIC REDUCTION OF SECODIONE DERIVATIVES - The invention relates to a process for the enantioselective enzymatic reduction of secodione derivatives. The secodione derivative is reduced with an oxidoreductase/dehydrogenase in the presence of NADH or NADPH as a cofactor. The secodione derivative is used in the reaction batch at a concentration of ≧10 g/l and the oxidized cofactor NAD or NADP formed by the oxidoreductase/dehydrogenase is regenerated continuously. | 02-16-2012 |
435150000 | Acetone containing product | 24 |
20090047718 | Methods and compositions for producing solvents - Described herein are methods, compositions and synthetic biology approaches for solvent production, including but not limited to butanol production. Described herein are recombinant bacteria and yeast strains which may be used in production of a solvent, including but not limited to butanol, from lignocellulosic and other plant-based feedstocks. Described herein are methods of producing solvents, including but not limited to butanol, using bacteria and yeast strains. Described herein are methods of producing organisms that display highly efficient butanol production. | 02-19-2009 |
20090162912 | PROCESS FOR CONTINUOUS SOLVENT PRODUCTION - A continuous process for production of solvents, particularly acetone-butanol-ethanol (ABE) using fermentation of solventogenic microorganisms and gas stripping is provided. The solventogenic microorganisms are inoculated in a nutrient medium containing assimilable carbohydrates (substrate) and optional other additives. Control of the solventogenic microorganism concentration in the fermentor (cell concentration) and the assimilable carbohydrate concentration in the fermentor, along with removal of solvents formed results in a continuous process for production of solvents. | 06-25-2009 |
20100124774 | METHOD OF PRODUCING BIOFUEL USING SEA ALGAE - The present invention relates to a method of producing biofuel, more specifically a method of producing biofuel comprising the steps of generating monosugars from marine algae, or from polysaccharides extracted from marine algae by treating the marine algae or the polysaccharides with a hydrolytic enzyme and/or a hydrolytic catalyst; and fermenting the monosugars using a microorganism to produce biofuel. The method of producing biofuel of the present invention solve the problem of raw material suppliance since it uses marine algae as a raw material for biomass, and reduce the production costs by excluding lignin eliminating process that has been required by the conventional method using wood-based raw materials, resulting in economic and environmental advantages. | 05-20-2010 |
20100261237 | FERMENTATIVE PRODUCTION OF ACETONE FROM RENEWABLE RESOURCES BY MEANS OF NOVEL METABOLIC PATHWAY - The invention describes a process for preparing acetone starting from acetyl-coenzyme A comprising process steps A. enzymatic conversion of acetyl-CoA into acetoacetyl-CoA B. enzymatic conversion of acetoacetyl-CoA into acetoacetate and CoA and C. decarboxylation of acetoacetate to acetone and CO | 10-14-2010 |
20100330633 | Integrated System and Process for Bioproduct Production - Processes and systems for production of bioproducts such as biofuels are provided. The bioproduct production processes and systems utilize pretreatment of a carbohydrate-containing feedstock to produce soluble sugar molecules and continuous conversion of the pretreated feedstock to a bioproduct by an immobilized fermenting microorganism. | 12-30-2010 |
20110129886 | Biorefinery Process for Extraction, Separation, and Recovery of Fermentable Saccharides, other Useful Compounds, and Yield of Improved Lignocellulosic Material from Plant Biomass - Non-food plant biomass is subjected to hot-water extraction in a pressurized vessel at an elevated temperature up to about 250° C. and at a pH below about 7.0, to yield an aqueous extract containing hemicellulosic components, other wood-derived compounds, and a lignocellulosic residue. The separated aqueous extract or liquor is purified and concentrated through a multi-step process producing fermentable sugars. At each stage, inhibitory chemicals such as acetic acid, lignin, and furfural are separated and eventually recovered as commercial chemicals. The lignocellulosic residue may be further processed, as a material with enhanced resistance to sorption of water, for manufacture of improved pulp and paper, construction materials, pellet fuel, and/or other useful products. | 06-02-2011 |
20120100585 | PROCESS FOR THE PRODUCTION OF ALCOHOLS AND/OR SOLVENTS FROM LIGNOCELLULOSIC BIOMASS WITH ACID RECYCLE OF SOLID RESIDUES - The present invention describes a process for the production of alcohols and/or solvents from a cellulosic or lignocellulosic substrate, comprising at least the following steps:
| 04-26-2012 |
20120252083 | FERMENTATION PROCESS FOR PRODUCING ISOPROPANOL USING A RECOMBINANT MICROORGANISM - The invention provides, inter alia, methods for the production of acetone, isopropanol and/or precursors of acetone and/or isopropanol by microbial fermentation of substrates comprising CO, genetically modified microorganisms of use in such methods, nucleic acids suitable for preparation of genetically modified microorganisms, a novel alcohol dehydrogenase and nucleic acids encoding same. | 10-04-2012 |
20130017585 | PROCESS FOR THE PRODUCTION OF ALCOHOLS AND/OR SOLVENTS FROM PAPERMAKING PULPS WITH RECYCLING OF NON-HYDROLYZED VEGETATIONAANM Ropars; MarcelAACI PalaiseauAACO FRAAGP Ropars; Marcel Palaiseau FRAANM Aymard; CarolineAACI LyonAACO FRAAGP Aymard; Caroline Lyon FR - This invention describes a process for the production of alcohols and/or solvents from cellulosic or lignocellulosic biomass that comprises at least the following stages:
| 01-17-2013 |
20130017586 | METHOD FOR PRODUCING ALCOHOLS AND/OR SOLVENTS FROM PAPER PULPS WITH RECYCLING OF THE NON-HYDROLYSATED PLANT MATERIAL IN A REGENERATION REACTORAANM Ropars; MarcelAACI PalaiseauAACO FRAAGP Ropars; Marcel Palaiseau FRAANM Aymard; CarolineAACI LyonAACO FRAAGP Aymard; Caroline Lyon FRAANM Guillaume; AnaisAACI Rueil-MalmaisonAACO FRAAGP Guillaume; Anais Rueil-Malmaison FRAANM Menir; SandraAACI GonesseAACO FRAAGP Menir; Sandra Gonesse FR - This invention describes a process for the production of alcohols and/or solvents from cellulosic or lignocellulosic biomass that comprises at least the following stages:
| 01-17-2013 |
20130109068 | Methods For Producing Acetone, Butanol, and Ethanol | 05-02-2013 |
20130164804 | Low Severity Pretreatment of Lignocellulosic Biomass - Methods are provided for preparing a hydrolysate containing soluble sugar molecules from biomass that contains cellulose and hemicellulose. Hemicellulose sugars are extracted in the process, and the resulting hydrolysate may be used to support microbial fermentation to produce products of interest. | 06-27-2013 |
20140004582 | CONDITIONING OF SO2-ETHANOL-WATER SPENT LIQUOR FOR FERMENTATION BY CLOSTRIDIA | 01-02-2014 |
20140073025 | METHOD AND APPARATUS FOR RECYCLING AND REUSING BEVERAGES AND OTHER LIQUIDS AND CONTAINER MATERIALS - A system for destruction and recycling of containers (such as bottles, cans and the like), as well as associated liquids, food products or other residue, greatly reduces waste discharge and/or disposal requirements. Packaging and other solids are shredded, ground or otherwise processed, while associated liquids are collected. Evaporation removes water for reuse, thus concentrating sugars and other food materials for utilization as agricultural amendments or stock for bio-product production. Bio-fuels/solvents are generated, typically using an Immobilized Microbe Bioreactor system modified for fuels/solvents production. | 03-13-2014 |
20140113341 | ABE FERMENTATION METHOD COMPRISING PRODUCT ABSORPTION THROUGH ISOPHORON - The invention relates to a method comprising the following method steps: A) providing an aqueous solution comprising microorganisms producing low-molecular, organic compounds; B) introducing at least one gas or gas mixture into the aqueous solution; C) recovering the gas flow through a compound comprising an isophoron; and optionally D) separating the low-molecular, organic compound from the composition comprising the isophoron. | 04-24-2014 |
20140170721 | METHODS FOR PRODUCING SUGARS FROM BIOMASS - The present invention provides methods for producing a mixture of sugars from a solid biomass feedstock using a counter current extraction apparatus and a dilute acidic solution. | 06-19-2014 |
20140242656 | METHOD FOR PRODUCING ALCOHOLS AND/OR SOLVENTS FROM PAPER PULPS WITH RECYCLING OF THE NON-HYDROLYSATED PLANT MATERIAL IN A REGENERATION REACTOR - This invention describes a process for the production of alcohols and/or solvents from cellulosic or lignocellulosic biomass that comprises at least the following stages:
| 08-28-2014 |
20140242657 | PROCESS FOR THE PRODUCTION OF ALCOHOLS AND/OR SOLVENTS FROM PAPERMAKING PULPS WITH RECYCLING OF NON-HYDROLYZED VEGETATION - This invention describes a process for the production of alcohols and/or solvents from cellulosic or lignocellulosic biomass that comprises at least the following stages:
| 08-28-2014 |
20140273122 | NOVEL MICROORGANISM OF THE GENUS BACILLUS - The invention provides a microorganism of the genus | 09-18-2014 |
20140315268 | METHOD OF PRODUCING BIOFUEL USING SEA ALGAE - The present invention relates to a method of producing biofuel, more specifically a method of producing biofuel comprising the steps of generating monosugars from marine algae, or from polysaccharides extracted from marine algae by treating the marine algae or the polysaccharides with a hydrolytic enzyme and/or a hydrolytic catalyst; and fermenting the monosugars using a microorganism to produce biofuel. The method of producing biofuel of the present invention solve the problem of raw material suppliance since it uses marine algae as a raw material for biomass, and reduce the production costs by excluding lignin eliminating process that has been required by the conventional method using wood-based raw materials, resulting in economic and environmental advantages. | 10-23-2014 |
20160068802 | Methods and Compositions for Producing Solvents - Described herein are methods, compositions and synthetic biology approaches for solvent production, including but not limited to butanol production. Described herein are recombinant bacteria and yeast strains which may be used in production of a solvent, including but not limited to butanol, from lignocellulosic and other plant-based feedstocks. Described herein are methods of producing solvents, including but not limited to butanol, using bacteria and yeast strains. Described herein are methods of producing organisms that display highly efficient butanol production. | 03-10-2016 |
20180023101 | MICROORGANISMS AND METHODS FOR THE CO-PRODUCTION OF ETHYLENE GLYCOL AND THREE CARBON COMPOUNDS | 01-25-2018 |
435151000 | Substrate contains grain or cereal material | 1 |
20110318796 | METHOD FOR EXTRACTING SOLUBLE SUGAR MOLECULES FROM BIOMASS MATERIAL - Methods are provided for preparing a hydrolysate containing soluble sugar molecules from biomass that contains cellulose and hemicellulose. Hemicellulose sugars are extracted in the process, and the resulting hydrolysate may be used to support microbial fermentation to produce products of interest. | 12-29-2011 |
435154000 | Substrate contains inorganic compound, other than water | 1 |
20160376615 | RECOMBINANT MICROORGANISMS AND USES THEREFOR - The invention provides recombinant microorganisms and methods for the production of acetone from gaseous substrates. For example, the recombinant microorganism may be modified to express an exogenous thiolase, an exogenous CoA transferase, and an exogenous decarboxylase. | 12-29-2016 |