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MICRO-ORGANISM, TISSUE CELL CULTURE OR ENZYME USING PROCESS TO SYNTHESIZE A DESIRED CHEMICAL COMPOUND OR COMPOSITION

Subclass of:

435 - Chemistry: molecular biology and microbiology

Patent class list (only not empty are listed)

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Class / Patent application numberDescriptionNumber of patent applications / Date published
435132000 Preparing oxygen-containing organic compound 1629
435072000 Preparing compound containing saccharide radical 1419
435690100 Recombinant DNA technique included in method of making a protein or polypeptide 1403
435106000 Preparing alpha or beta amino acid or substituted amino acid or salts thereof 329
435117000 Preparing heterocyclic carbon compound having only O, N, S, Se, or Te as ring hetero atoms 231
435680100 Enzymatic production of a protein or polypeptide (e.g., enzymatic hydrolysis, etc.) 225
435166000 Preparing hydrocarbon 187
435128000 Preparing nitrogen-containing organic compound 107
435710100 Using a micro-organism to make a protein or polypeptide 95
435168000 Preparing element or inorganic compound except carbon dioxide 85
435700100 Using tissue cell culture to make a protein or polypeptide 56
435170000 Using bacteria 54
435052000 Preparing compound containing a cyclopentanohydrophenanthrene nucleus; nor-, homo-, or D-ring lactone derivatives thereof 35
435042000 Process involving micro-organisms of different genera in the same process, simultaneously 24
435067000 Preparing compound containing a carotene nucleus (i.e., carotene) 22
435171000 Using fungi 22
435043000 Preparing compound having a 1-thia-4-aza-bicyclo (3.2.0) heptane ring system (e.g., penicillin, etc.) 16
435131000 Preparing organic compound containing a metal or atom other than H, N, C, O, or halogen 14
435047000 Preparing compound having a 1-thia-5-aza-bicyclo (4.2.0) octane ring system (e.g., cephalosporin, etc.) 10
435127000 Preparing compound containing at least three carbocyclic rings 9
435130000 Preparing sulfur-containing organic compound 5
20110195466MICROORGANISMS FOR THE PRODUCTION OF ADIPIC ACID AND OTHER COMPOUNDS - The invention provides a non-naturally occurring microbial organism having an adipate, 6-aminocaproic acid or caprolactam pathway. The microbial organism contains at least one exogenous nucleic acid encoding an enzyme in the respective adipate, 6-aminocaproic acid or caprolactam pathway. The invention additionally provides a method for producing adipate, 6-aminocaproic acid or caprolactam. The method can include culturing an adipate, 6-aminocaproic acid or caprolactam producing microbial organism, where the microbial organism expresses at least one exogenous nucleic acid encoding an adipate, 6-aminocaproic acid or caprolactam pathway enzyme in a sufficient amount to produce the respective product, under conditions and for a sufficient period of time to produce adipate, 6-aminocaproic acid or caprolactam.08-11-2011
20090275094PROCESS FOR PRODUCING SULFUR-CONTAINING HYDROXYCARBOXYLIC ACID - There is provided is a process for producing a sulfur-containing α-hydroxycarboxylic acid compound represented by the formula (2):11-05-2009
20090053781Method for Producing 2-hydroxy-4-(methylthio)butyric Acid - A method for producing 2-hydroxy-4-(methylthio)butyric acid which comprises the following steps (A), (B) and (C): 02-26-2009
20120040418METHOD FOR PRODUCING 3-MERCAPTOPROPIONIC ACID OR SALT THEREOF - The present invention provides is a method for producing 3-mercaptopropionic acid from 3-mercaptopropionamide or a salt thereof with the use of an amidase. The method enables the production of 3-mercaptopropionic acid on an industrial scale through an enzymatic reaction.02-16-2012
20100203601PROCESS FOR SURFACE ACTIVATION AND/OR DEVULCANIZATION OF SULFUR-VULCANIZED RUBBER PARTICLES - Process for surface activation and/or devulcanization of sulfur-vulcanized rubber particles. In order to break the sulfur bridges and to reduce the sulfur, the rubber particles are treated in a biotechnological manner in a medium with mesophilic anaerobic and/or optionally anaerobic and/or microaerophilic bacteria and/or with one or more enzyme systems of such bacteria. The thus-treated activated rubber particles show improved vulcanization properties in comparison with non-treated rubber particles, and permit the production of better quality articles.08-12-2010
435066000 Preparing compound other than saccharide containing alloxazine or isoalloxazine nucleus 5
20080311617Modified Transketolase and Use Thereof - The present invention relates to a improved process for the biotechnological production of compounds for which ribose-5-phosphate, ribulose-5-phosphate or xylulose-5-phosphate is biosynthetic precursor like riboflavin (vitamin B12-18-2008
20100173356INCREASED PRODUCTION OF A TARGET PRODUCT VIA STABILIZATION OF mRNA - The present invention relates to newly identified mRNA stabilizing elements useful for the production of a target fermentation product, such as e.g. vitamins or enzymes, in particular riboflavin (vitamin B2), biotin, pantothenic acid (vitamin B5), folic acid, thiamin, pyridoxine (vitamin B6), vitamin B12, xylanase, amylase, protease, glucanase, amylomaltase or maltogenic amylase.07-08-2010
20110312026PROCESS FOR THE PRODUCTION OF RIBOFLAVIN - The invention relates to processes and means for the biotechnologically fermentative production of riboflavin (hereinafter also referred to as vitamin B2) and means for the implementation of this process, in particular a modified microbial host cell with increased riboflavin yield. The invention thus provides new processes and means for the regulation of the expression of enzyme activities involved in the riboflavin production of the host cell.12-22-2011
20110312025IMPROVED PRODUCTION OF RIBOFLAVIN - The present invention provides an improved biotechnological production of riboflavin (also referred herein as vitamin B2) through modification in the operon containing the riboflavin biosynthetic genes (rib operon), in particular modifications of/in the leader sequences (rib leader) upstream of the corresponding riboflavin biosynthetic genes (rib operon). Furthermore, the present invention relates to genetically engineered microorganisms carrying said modified sequences, processes to generate said modified sequences/microorganisms and the use thereof for production of riboflavin.12-22-2011
20130189731MODIFIED TRANSKETOLASE AND USE THEREOF - The present invention relates to a improved process for the biotechnological production of compounds for which ribose-5-phosphate, ribulose-5-phosphate or xylulose-5-phosphate is biosynthetic precursor like riboflavin (vitamin B07-25-2013
435064000 Preparing compound other than saccharide containing a tetracycline nucleus (e.g., naphacene, etc.) 2
20100291622NOVEL COMPOUND, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF - The present invention provides compounds which exhibit an inhibitory effect on undecaprenyl diphosphate synthase of microbes and thereby they are expected to be used clinically as pharmaceutical agents for infectious diseases caused by bacteria.11-18-2010
20130122541MICROORGANISM PRODUCTION OF HIGH-VALUE CHEMICAL PRODUCTS, AND RELATED COMPOSITIONS, METHODS AND SYSTEMS - This invention relates to metabolically engineered microorganism strains, such as bacterial strains, in which there is an increased utilization of malonyl-CoA for production of a chemical product, which includes polyketides and 3-hydroxypropionic acid.05-16-2013
435063000 Preparing compound containing a prostaglandin nucleus 1
20120142047Purification and Separation Treatment Assembly (PASTA) for Biological Products - An assembly capable of capturing and purifying expressed biological products during or at the end of a bioreaction cycle is disclosed wherein a binding resin is kept separated from the contents of the bioreactor allowing capturing, harvesting and purification of biological products in a bioreactor; the invention additionally provides means of removing undesirable metabolic products as well as provides for efficient loading of chromatography columns.06-07-2012
Entries
DocumentTitleDate
20110177551METHOD FOR PRODUCING A CHEMICAL PRODUCT AND CONTINUOUS FERMENTATION APPARATUS - To control flow velocity of a culture liquid inside a membrane separation tank without giving influences to culture conditions in the fermentation tank, and also suppress precipitation of microorganisms or culture cells so that the production efficiency of the chemical product can be improved, in a method for producing a chemical product including the steps of: cultivating microorganisms or culture cells in a fermentation tank; transferring a culture liquid from the fermentation tank to a membrane separation tank so as to filter the culture liquid through a separation membrane; and collecting a fermentation product from a filtration liquid as the chemical product while refluxing an unfiltered culture liquid that has not been filtered so as to be joined to the culture liquid on an upstream side of the membrane separation tank, one portion of the culture liquid to be transferred from the fermentation tank is allowed to bypass the membrane separation tank depending on a pressure at the culture liquid flow-in side of the membrane separation tank.07-21-2011
20110207170Bioreactor Exhaust - An exhaust system suitable for high volume exhaust from flexible disposable bags is described that prevents nutrient media volume loss and prevents cross-contamination without using any filters. The invention described here allows the use of disposable two-dimensional bioreactors for the cultivation of bacterial and other organisms and cells require high aeration.08-25-2011
20100062483PRODUCTION OF BIO-BASED MATERIALS USING PHOTOBIOREACTORS WITH BINARY CULTURES - A method, device and system for producing preselected products, (either finished products or preselected intermediary products) from biobased precursors or Co03-11-2010
20100159509Methods for increasing enzymatic hydrolysis of cellulosic material in the presence of a peroxidase - The present invention relates to methods for increasing hydrolysis of a cellulosic material, comprising: hydrolyzing the cellulosic material with an enzyme composition in the presence of a polypeptide having peroxidase activity.06-24-2010
20110195449Recombinant Thraustochytrids that Grow on Sucrose, and Compositions, Methods of Making, and Uses Thereof - The present invention is directed to recombinant thraustochytrids that grow on sucrose and cell cultures comprising the recombinant thraustochytrids as well as methods of producing cell cultures, biomasses, microbial oils, compositions, and biofuels using the recombinant thraustochytrids.08-11-2011
20110195448Recombinant Thraustochytrids that Grow on Xylose, and Compositions, Methods of Making, and Uses Thereof - The present invention is directed to recombinant thraustochytrids that grow on xylose and cell cultures comprising the recombinant thraustochytrids as well as methods of producing cell cultures, biomasses, microbial oils, compositions, and biofuels using the recombinant thraustochytrids.08-11-2011
20100120087Enzymatic or Organic Catalytic Chemical Reactions - In an aspect, a perturbation is applied to a system comprising an enzymatic chemical reaction and/or an organic catalytic chemical reaction with the perturbation being non-directional (average of the force applied by the perturbation being zero) with respect to a variable of the system. A directional effect is caused with respect to the said enzymatic or organic catalytic chemical reaction as a result of the perturbation and an asymmetry of the perturbed system. The present invention also embodies an apparatus comprising a site for an enzymatic or organic catalytic chemical reaction and a device controlled to perturb a system that includes the enzymatic or organic catalytic chemical reaction, the average of the force applied by the perturbation being zero, a directional effect being caused with respect to the chemical reaction as a result of the perturbation and an asymmetry of the perturbed system.05-13-2010
20100112632COMPOSTER MECHANISM - A rotary composter having a fuselage member where a drive system is configured to rotate the fuselage member where the end caps are substantially stationary and do not rotate and the fuselage member has a plurality of longitudinally extending slats contained therein.05-06-2010
20100143965METHOD FOR PRODUCTION OF ANTIMUTAGENIC SUBSTANCE USING LACTIC ACID BACTERIUM - Disclosed is a method for producing an antimutagenic substance by using a lactic acid bacterium, which can produce the antimutagenic substance in a large quantity in an extremely simple manner and is economically advantageous; particularly a method for producing an antimutagenic substance effective for a carcinogenic substance, particularly a heterocyclic amine (HCA) which is a carcinogenic substance derived from a food, by using a lactic acid bacterium. Specifically disclosed is a method for producing an antimutagenic substance by using a lactic acid bacterium, which is characterized by suspending the lactic acid bacterium in a poorly nutrient or nutrient-free medium and leaving the lactic acid bacterium in the medium. Preferably, the poorly nutrient or nutrient-free medium is selected from the group consisting of physiological saline, a phosphate-buffered saline without a calcium or magnesium salt (PBS (−)), a citrate buffer, a distilled water, an ion-exchanged water, a natural water, a well water, a tap water, a mineral-added water, a vitamin-added water, an ion supply beverage for an athlete and the like. More preferably, the lactic acid bacterium is 06-10-2010
20100041095PNEUMATIC BIOREACTOR - A pneumatic bioreactor includes a vessel containing a fluid to be mixed and at least one mixing device driven by gas pressure. A first embodiment includes a floating impeller that rises and falls in the fluid as gas bubbles carry it upward to the surface where the gas is then vented, permitting the impeller to sink in the fluid. The floating impeller may be tethered to a second impeller with a flexible member and pulley. The mixing speed is controlled with electromagnets in the vessel acting upon magnetic material in the impeller or its guides. In another embodiment, floating pistons mix the fluid, pushing it through a mixing plate with one or more apertures. In a third embodiment, the mixing device is a rotating drum with bubble-catching blades and rotating mixing plates with apertures. The top of the vessel for these mixers may include a closed top and sterile filters.02-18-2010
20130071877Chimeric isoprenoid synthases and uses thereof - Provided is a chimeric isoprenoid synthase polypeptide including a first domain from a first isoprenoid synthase joined to a second domain from a second, heterologous, isoprenoid synthase, whereby the chimeric isoprenoid synthase is capable of catalyzing the production of isoprenoid reaction products that are not produced in the absence of the second domain of the second, heterologous, isoprenoid synthase. Also provided is a chimeric isoprenoid synthase polypeptide including an asymmetrically positioned heterologous domain, whereby the chimeric isoprenoid synthase is capable of catalyzing the production of isoprenoid reaction products that are not produced when the domain is positioned at its naturally-occurring site in the isoprenoid synthase polypeptide.03-21-2013
20110014648A MICROBIOLOGICAL PRODUCTION METHOD AND EQUIPMENT FOR ITS USE - When using the equipment and method in accordance with this invention, it is possible to implement biotechnological production e.g. in biorefineries in such a way that it is possible to make use of the phenomena of the gas-liquid interface and interfaces between other phases by means of a moving process solution and gas led into it. This way, production and post-treatment methods can also be integrated, and desired acceleration of reactions and cost reductions can be achieved.01-20-2011
20110045528APPARATUS AND METHOD FOR ENHANCED DISRUPTION AND EXTRACTION OF INTRACELLULAR MATERIALS FROM MICROBIAL CELLS - Provided are surprisingly beneficial osmotic stress shock methods for facilitating disruption and/or extraction of microorganisms, comprising a synergistic combination of at least one hypotonic shock and at least two hypertonic shocks, wherein the last shock is a hypertonic shock. Preferred aspects of the invention relate to facilitating disruption of a broad spectrum of microorganisms (e.g., algae, bacteria, yeast, fungus, etc.). In particular aspects the microbial cells are subjected to: a hypertonic/hypotonic/hypertonic tertiary shock; a hypotonic/hypertonic/hypertonic tertiary shock; or a hypotonic/hypertonic/hypotonic/hypertonic quaternary shock. Particular aspects further comprise disrupting and/or extracting of the shocked microbial cells, and isolating a cellular constituent or bioproduct (e.g., biofuel, biocrude, bioenergy, biogas, biodiesel, bioethanol, biogasoline, pharmaceuticals, nutraceuticals, food, vitamins, feedstock, dyes, colorants, sulfur, fertilizer, bioplastic) therefrom. In particular preferred aspects, facilitation of algae disruption and/or extraction is provided and in certain embodiments, isolation of at least one of lipid, oil, and triacylglycerol is enhanced.02-24-2011
20120115185 DEVICE AND METHOD FOR RECOVERING BIOGAS - A device for recovering biogas, comprising at least one fermenter (05-10-2012
20120237970METHOD FOR OBTAINING NATURAL EXTRACTS, OLEORESINS, CONDIMENTS, COLORANTS, FLAVORING SUBSTANCES AND AROMAS FROM AROMATIC PLANT SUBSTANCES, ALFALFA, FLOWERS WITH PIGMENTS, AND VEGETABLES - A method for obtaining natural extracts, oleoresins, colorants flavors and aromas from aromatic plant substances, alfalfa, flowers with pigments, and vegetables, which includes washing the plant substances and vegetables, rinsing with water, milling and sifting the resulting product yielding a pulp phase and a cellulose phase. The pulp phase is transferred to fermentation tanks and a first centrifugation of the fermented pulp phase is then performed yielding two phases: phase (A) containing water, mineral salts and other water-soluble substances, with natural extracts, oleoresins, colorants, aromas and flavors and phase (B) in the form of a paste in which the moisture has been reduced to 50%, performing a second centrifugation of the mentioned phase (A), which causes the separation of natural extracts, oleoresins, colorants, aromas and flavors from the water and other water-soluble substances.09-20-2012
20090130705NADP-Dependent Glucose Dehydrogenase From Gluconobacter Oxydans - The present invention relates to microorganisms genetically engineered to increase yield and/or efficiency of biomass production from a carbon source, such as e.g. glucose. Processes for generating such microorganisms are also provided by the present invention. The invention also relates to polynucleotide sequences comprising genes that encode proteins that are involved in the bioconversion of a carbon source such as e.g. glucose into biomass. The invention also features polynucleotides comprising the full-length polynucleotide sequences of the novel genes and fragments thereof, the novel polypeptides encoded by the polynucleotides and fragments thereof, as well as their functional equivalents. Also included are processes of using the polynucleotides and modified polynucleotide sequences to transform host microorganisms leading to a microorganism with reduced carbon source diversion, i.e. higher yield and/or efficiency of biomass production from a carbon source such as e.g. glucose.05-21-2009
20100178670PROCESSES OF PRODUCING FERMENTATION PRODUCTS - The invention relates to a process of fermenting material derived from lignocellulose-containing material into a fermentation product by fermenting said material derived from lignocellulose-containing material using a fermenting organism obtained from a process of fermenting starch-containing material.07-15-2010
20100209965CATALYTIC PYROLYSIS OF FINE PARTICULATE BIOMASS, AND METHOD FOR REDUCING THE PARTICLE SIZE OF SOLID BIOMASS PARTICLES - A process is disclosed for converting a particulate biomass material to a bioliquid. In the process the biomass material is mixed with a heat transfer medium and a catalytic material, and heated to a temperature in the range of from 150 to 600° C. The particle size of the solid biomass may be reduced by abrasion in admixture with inorganic particles under agitation by a gas. The biomass particles of reduced size obtained in the abrasion process may be converted to bioliquid in any of a number of conversion processes.08-19-2010
20100184130ENGINEERED BIOMASS WITH INCREASED OIL PRODUCTION - The present invention relates to a genetically modified plant having an increased amount of oil in its green biomass as compared to the oil in the green biomass of its non-genetically modified counterpart. The plants may be used for producing bio-fuels such as biodiesel fuel.07-22-2010
20090035811Artificial scaffolding material for protein retention and use of the same - The present invention provides an artificial scaffolding material for retaining proteins suitable for placing contiguously one species or two or more species of proteins such as enzymes. To this end, the artificial scaffolding material for retaining proteins is provided with a cell and scaffolding proteins heterologous to the cell and placed on the surface layer side of the cell at an extent that allows aggregation properties to be conferred to the cell, and provided with a plurality of non-covalently binding protein-binding domains arranged in tandem.02-05-2009
20100173355Means for sequestration and conversion of COx and NOx, CONOx - The instant invention presents means for sequestering CO07-08-2010
20110281298METHOD AND APPARATUS TO EXTRACTED AND REDUCE DISSOLVED HEMI-CELLULOSIC SOLIDS IN BIOMASS FOLLOWING PRE-HYDROLYSIS - A method to wash and remove dissolved solids from biomass including: discharging a biomass slurry from a pretreatment vessel to a biomass slurry retention device; adding recovered wash liquid to dilute the biomass slurry in the retention device, wherein the recovered wash liquid is extracted from a drainer device upstream of the first retention device; discharging the diluted biomass slurry from the retention device to the drainer device; separating wash liquid with dissolved solids from the diluted biomass slurry in the drainer device and discharging a concentrated biomass slurry from the drainer device, and recovering the wash liquid from the diluted biomass slurry in the drainer device and transferring the recovered wash liquid to the retention device.11-17-2011
20100184128PRODUCTION OF PRODUCTS OF PHARMACEUTICAL INTEREST IN PLANT CELL CULTURES - The present invention relates to transgenic plant cell cultures comprising transgenic plant cells comprising a plurality of nucleic acids heterologous to said plant, each of said nucleic acids comprising a coding sequence encoding a pharmaceutical product of interest operably linked to one or more regulatory elements for directing expression of said coding sequence in said plant cell, said nucleic acids being stably integrated at or adjacent to native rDNA of said plant cell; methods of producing the transgenic plant cell culture; and methods of producing a pharmaceutical product of interest using the transgenic plant cell culture.07-22-2010
20110143394Methods and Means for Metabolic Engineering and Improved Product Formation by Micro-Organisms - The invention relates to the field of biochemistry, molecular biology and microbiology. More specific the invention relates to methods and means for metabolic engineering and improved product formation by a filamentous micro-organism or a low G+C gram-positive bacterium.06-16-2011
20110294159Biocompatible Article for the Treatment of Water and Production of Energy - A biocompatible article including (a) a biocompatible hydrogel; (b) an adhesive coating on at least a portion of the hydrogel; and (c) one or more organisms adhered to at least a portion of the adhesive coating is disclosed.12-01-2011
20090123964Novel Gene GMS 08 - The present invention relates to microorganisms genetically engineered to increase yield and/or efficiency of biomass production from a carbon source, such as e.g. glucose. Processes for generating such microorganisms are also provided by the present invention. The invention also relates to polynucleotide sequences comprising genes that encode proteins that are involved in the bioconversion of a carbon source such as e.g. glucose into biomass. The invention also features polynucleotides comprising the full-length polynucleotide sequences of the novel genes and fragments thereof, the novel polypeptides encoded by the polynucleotides and fragments thereof, as well as their functional equivalents. Also included are processes of using the polynucleotides and modified polynucleotide sequences to transform host microorganisms leading to a microorganism with reduced carbon source diversion, i.e. higher yield and/or efficiency of biomass production from a carbon source such as e.g. glucose.05-14-2009
20120107866METHODS TO INCREASE AND HARVEST DESIRED METABOLITE PRODUCTION IN ALGAE - Enhanced yields of photosynthetically fixed carbon produced by hypersaline photosynthetic algae are provided by co-culturing with a halophilic archaea. Further, methods are provided to control harvesting of desired metabolic products from hypersaline photosynthetic algae by controlling caspase activity.05-03-2012
20120270263ENZYME COMPLEX FROM TRICHODERMA REESEI AND P. FUNICULOSUM ENZYMES - The invention relates to an improved enzyme complex having a plurality of enzyme activities of an expression product obtained by fermentation of the genus 10-25-2012
20110201050Gas Scrubbed Perfusion Filter - Fine gas bubbles traveling at fast speed are employed to scrub a hard-surface filter for harvesting liquids from suspensions including those consisting of nutrient media and cell culture, on a continuous basis without clogging the filters.08-18-2011
20110171685Enzymatic Hydrolysis Of Pretreated Lignocellulose-Containing Material With Paper Mill Sludge - A method for producing a fermentation product from a lignocellulose-containing material comprises pre-treating the lignocellulose-containing material; introducing paper mill sludge to the pre-treated lignocellulose-containing material; exposing the pre-treated lignocellulose-containing material to an effective amount of hydrolyzing enzyme; and adding a fermenting organism to produce a fermentation product. In an embodiment, the paper mill sludge comprises deinking paper sludge.07-14-2011
20130217066PIGMENT PRODUCTION BY LATEX-EMBEDDED MICROORGANISMS - A process is provided for the extraction of pigments from immobilized microorganisms. Pigment producing cells are immobilized and dried in a binder matrix, and pigments are recovered from the cells by liquid rinsing. Following release of the pigments, cellular metabolism of the microorganisms is revived in culture medium and pigments are regenerated. Pigments are then recovered from the immobilized cells by successive rounds of dehydration/rinsing/cell recovery.08-22-2013
20120295303PHOTOSYNTHETIC ORGANISMS AND CELLS ADAPTED TO METABOLIZE PHOSPHITE AS A SOURCE OF PHOSPHORUS - System, including methods and compositions, for making and using photosynthetic organisms and cells that are adapted transgenically to metabolize phosphite as a source of phosphorus for supporting growth.11-22-2012
20100143967Compositions and methods for enhancing the degradation or conversion of cellulose-containing material - The present invention relates to methods for degrading or converting a cellulose-containing material, comprising: treating the cellulose-containing material with an effective amount of a cellulolytic enzyme composition comprising a polypeptide having cellulolytic enhancing activity, and one or more (several) components selected from the group consisting of a CEL7 polypeptide having endoglucanase activity, a CEL12 polypeptide having endoglucanase activity, a CEL45 polypeptide having endoglucanase activity, a CEL7 polypeptide having cellobiohydrolase activity with a cellulose binding domain, and a CEL7 polypeptide having cellobiohydrolase activity without a cellulose binding domain. The present invention also relates to such cellulolytic enzyme compositions.06-10-2010
20080293096Enzyme and Template-Controlled Synthesis of Silica from Non-Organic Silicon Compounds as Well as Aminosilanes and Silazanes and Use Thereof - The present invention relates to a method for synthesis of amorphous silicon dioxide (silica, condensation products of silicic acid) and other polymeric metal (IV) compounds from non-organic silicon compounds or metal (IV) compounds as well as from aminosilanes and silazanes, whereby (I) a template (collagen or another molecule, interacting with orthosilicic acid or polymeric silicic acid and salts thereof or other metal (IV) compounds) and (2) a silicase/carbonic anhydrase or a silicatein or similar polypeptide are used for synthesis. Said invention also relates to the technical use thereof.11-27-2008
20090029410Lipases from Thermophilic Anaerobes - The inventors have identified polypeptides having lipase activity in anaerobic thermo-philic bacteria. Accordingly, the invention provides a process for hydrolyzing an ester bond in a substrate, which comprises treating the substrate with a particular lipase (a polypeptide having lipase activity). The invention also provides a lipase for use in the process and a polynucleo-tide encoding the lipase.01-29-2009
20090098598PROCESS FOR INTERGRATED UTILIZATION OF THE ENERGY AND MATERIAL CONTENTS OF HYDROLYSATES - A process for integrated utilization of the energy and material contents of hydrolysates and solids obtained in the enzymatic hydrolysis of renewable raw materials, in which the resulting hydrolysis solution is used as a carbon source in fermentations and the unhydrolysed solids are sent to biogas production.04-16-2009
20090081723BIOREACTOR, CELL CULTURE METHOD, AND SUBSTANCE PRODUCTION METHOD - The present invention achieves a smaller difference between a dissolved oxygen concentration in an upper part of a culture tank and a dissolved oxygen concentration in a lower part of the culture tank. The present invention comprises: a culture tank; a sparger means arranged in a lower part of the culture tank; and multiple impellers being arranged in multiple stages in a vertical direction of the culture tank and having a larger mass transfer capacity coefficient K03-26-2009
20110229930MICROORGANISM COMPRISING PARTICLES AND USES OF SAME - A particle is disclosed. The particle comprising: (i) at least one inner core which comprises a solid matrix of nutrients for microorganism growth; (ii) an inner membrane being fabricated from a water-soluble polymer, the inner membrane surrounding the inner core and a population of dried microorganisms; and (iii) an outer porous membrane surrounding the inner membrane, the outer porous membrane being insoluble in water. Methods of generating same, propagating microorganisms within and uses of same are also disclosed.09-22-2011
20110143395Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from alicyclobacillus acidocaldarius and related organisms, methods - Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from 06-16-2011
20100273210Biofuel manufacturing methods and systems incorporating radiocarbon analysis techniques - The systems and methods described herein are directed toward the use of radiocarbon analysis techniques in the manufacture of biofuel products. Among other things, methods and systems for using measured fossil-fuel-derived carbon content in biofuel products to guide the design and modification of biofuel manufacturing systems are disclosed.10-28-2010
20110177550PROCESS FOR THE TREATMENT OF WATER AND PRODUCTION OF BIOMASS AND ASSOCIATED SYSTEMS - A process for the treatment of a saline water including: treating the water to adjust the salinity thereof and produce treated water having a predetermined salinity level; and directing at least a portion of the treated water having said predetermined salinity level to a bioreactor housing a microalgae for generating biomass; wherein said predetermined salinity level of the treated water is predicated by the specie of microalgae housed in the bioreactor.07-21-2011
20100184129SILICON MOULDED PART COMPRISING LUMINOUS BODIES - The invention relates to moulded parts containing a plurality of luminous bodies incorporated into a silicon matrix, the silicon matrix consisting of an inner soft silicon matrix A which is surrounded by at least one hard silicon matrix B. The silicon matrix B is optionally coated with a top coat C.07-22-2010
20100240095Polypeptides having cellobiohydrolase II activity and polynuleotides encoding same - The present invention relates to isolated polypeptides having cellobiohydrolase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.09-23-2010
20100240094FERMENTER FOR GENERATING BIOGAS FROM PUMPABLE ORGANIC MATERIAL - The invention relates to a fermenter for generating biogas from pumpable organic material with a low content of organic dry matter (oTS), comprising at least one inlet for the pumpable organic material, at least one fixed bed reactor for the pumpable organic material with at least one primary and one secondary section and at least one outlet the remaining fermentation residue. Furthermore, the fermenter can optionally comprises at least one sedimentation chamber for the pumpable organic material, arranged between the primary and secondary sections and at least one recycling section connected to the sedimentation chamber and designed such that specific lighter fractions of the pumpable organic material can be recovered and reintroduced to the rising (primary) section of the fixed bed reactor or a preceding or subsequent conventional fermenter.09-23-2010
20100255533Method for processing shark's cartilage marrow - A method for processing shark's cartilage marrow comprises steps of: (A). dissolving the shark's cartilage marrow by plant enzymes; (B). hydrolyzing the dissolved mixture obtained from step (A) with pure water and removing impurities from the hydrolyzed product by the specific gravity difference between the impurities and the hydrolyzed product; (C). homogenizing the product obtained from step (B) into an aqueous solution; (D). processing the aqueous solution with a precipitation procedure; and (E). removing excess water by chromatographic separation and obtaining shark's cartilage marrow extract (SDS; shark distillated for saccharide) via specific gravity difference.10-07-2010
20110003331Method for enhanced production of biofuels and other chemicals using biological organisms - The invention of this disclosure, also known as the method of this disclosure, provides the means of improved Chemical Product production from chemical production systems that use biological organisms to produce the desired chemicals. This improved production is by means of subjecting chemical producing organisms to vibration waves or to an electrical voltage potential. The waves or voltage accomplish one of two things or both: they will improve the extraction of the chemicals from the bodies and cells of organisms, or they will increase the rate at which the organisms synthesize chemicals. To illustrate how one of many possible chemical production systems can incorporate this method, a specific configuration for a continuous chemical production system called the Oil Production System 01-06-2011
20100062482Fermentation Device Comprising a Coupled Substrate and Sediment Transport Mechanism and Method for Operating the Fermentation Device - A fermentation device for biological degradation of substrate containing organic material and for recovery of biogas produced by degradation has an elongate closed container having a first end and a second end opposite the first end. The first end has an inlet opening for untreated substrate and the second end has at least one removal opening for treated substrate. The container has at least one removal opening for biogas. The container has several reaction cells provided with individually driven mixing units. The mixing units have mixing unit shafts positioned transversely to a longitudinal extension of the container and mixing impellers mounted on the mixing unit shafts and driven on a circular path. The mixing unit shafts are arranged at axial spacings smaller than a diameter of the mixing units so that the mixing impellers when the mixing unit shafts rotate pass trough an overlap range.03-11-2010
20090075326REPRODUCTIVE ABLATION CONSTRUCTS - The present invention relates to the regulation of reproductive development, particularly to the genetic ablation of reproductive tissues in angiosperm and gymnosperm species. Reproductive-preferred promoters, regulatory elements, and cytotoxic nucleotide sequences are disclosed herein, as are constructs and methods for genetic ablation.03-19-2009
20100055736VIRAL VECTOR AND USES THEREOF - The invention relates to a viral vector comprising a mutated replicon of the Semliki Forest virus (SFV) in the nucleotide sequence encoding subunit nsp2 of the SFV replicase. Said viral vector can be used to generate stable cell lines which can constitutively express heterologous products of interest.03-04-2010
20120196321SELECTABLE MARKERS AND RELATED METHODS - The invention relates to newly identified selectable marker systems, cells for use in a selectable marker system, and methods for using the selectable marker systems.08-02-2012
20110027828Enzymatic Modification in a Continuously Regenerated Packed Bed Column - A process for the modification of a substrate comprising passing the substrate through a packed bed column of a specific volume of immobilized enzyme wherein the substrate enters the column at or near one end of the column (the ‘inlet end’) and the modified substrate exits at or near the opposite end of the column (the ‘outlet end’), a portion of the volume of immobilized enzyme is periodically removed at or near to the inlet end of the column, and an equivalent portion of immobilized enzyme is periodically added at or near to the outlet end of the column.02-03-2011
20090246826Bi-Directional Selection Markers With Improved Activity - The present invention discloses a polypeptide selected from the group consisting of: a polypeptide having an amino acid sequence according to SEQ ID NO 3, a polypeptide having an amino acid sequence according to SEQ ID NO 6, a polypeptide having an amino acid that is substantially homologous to the sequence of SEQ ID NO 3 and a polypeptide having an amino acid that is substantially homologous to the sequence of SEQ ID NO 6, the polypeptide displaying acetamidase activity and providing a reverse selection on fluoroacetamide with an efficiency of at least 95%, preferably at least 96%, more preferably at least 97%, more preferably at least 98%, more preferably at least 99%, most preferably 100%. The gene encoding the polypeptide of the invention is used as an efficient bi-directional selection marker in the construction of selection marker free strains, in particular for processes for the production of a compound of interest.10-01-2009
20090203067Photobioreactor Systems and Methods for Growing Organisms - Photobioreactors and systems for growth of a photosynthetic organism are provided herein. The systems and photobioreactors can comprise features and modifications in order to improve photosynthetic growth efficiency and light energy utilization. Also provided are methods and systems to improve the cost-effectiveness of a photobioreactor system for growth of a photosynthetic organism.08-13-2009
20090130707Methods of reducing the inhibitory effect of a redox active metal ion on the enzymatic hydrolysis of cellulosic material - The present invention relates to methods of producing a cellulosic material reduced in a redox active metal cation having a redox potential (E05-21-2009
20100311110Thermal and acid tolerant beta xylosidases, arabinofuranosidases, genes encoding, related organisms, and methods - Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from 12-09-2010
20110008826METHOD OF PRODUCING COMPOUND ORIGINATING FROM POLYSACCHARIDE-BASED BIOMASS - A method of producing a compound originating from a polysaccharide-based biomass includes at least one of a saccharification step that produces a sugar solution containing a monosaccharide and/or an oligosaccharide from a product obtainable by hydrolyzing the polysaccharide-based biomass; a fermentation step that ferments the sugar solution containing the monosaccharide and/or oligosaccharide originating from the polysaccharide-based biomass; and a treatment that removes a fermentation inhibitor with the use of a separation membrane having a glucose removal rate and an isopropyl alcohol removal rate which simultaneously satisfy the following relationships (I) and (II) when a 500 ppm aqueous glucose solution at pH 6.5 at 25° C. and a 500 ppm aqueous isopropyl alcohol solution at pH 6.5 at 25° C. are respectively permeated through the membrane at an operation pressure of 0.5 MPa, prior to the saccharification step and/or in the step prior to the fermentation step:01-13-2011
20100317053PROCESS MACHINERY FOR FEEDING PRE-TREATED LIGNOCELLULOSIC MATERIALS INTO BIOREACTORS FOR BIO-FUELS AND BIOCHEMICALS - Methods for mixing a pretreated cellulosic biomass feedstock using a centrifugal mixer prior to reactions in a bioreactor.12-16-2010
20100184131AMENDMENT-FREE SLUDGE COMPOSTING - A composting system for promoting aerobic microbial activity in a composting bed. The system includes at least one composting bay for receiving composting material and an agitator for aerating and displacing composting material as it travels through the composting bay. Compost produced by the system is used in place of traditional woody amendment material for mixing with incoming material to be composted.07-22-2010
20110111453Compositions for saccharification of cellulosic material - The present invention relates to enzyme compositions for high temperature saccharification of cellulosic material and to uses thereof.05-12-2011
20100143966Method for facilitating fermentation of high solids compositions - The present invention features a method for facilitating the fermentation of a high solids composition. The method involves subjecting the high solids composition to granular starch hydrolyzing enzyme during the fermentation process to provide a steady source of glucose. Moreover, the instant method is carried out under reduced pressure to selectively remove volatile components such as ethanol and water from the fermentation vessel.06-10-2010
20110244512PENTOSE PHOSPHATE PATHWAY UPREGULATION TO INCREASE PRODUCTION OF NON-NATIVE PRODUCTS OF INTEREST IN TRANSGENIC MICROORGANISMS - Coordinately regulated over-expression of the genes encoding glucose 6-phosphate dehydrogenase [“G6PDH”] and 6-phospho-gluconolactonase [“6PGL”] in transgenic strains of the oleaginous yeast, 10-06-2011
20110250636Novel gene GMS 01 - The present invention relates to microorganisms genetically engineered to increase yield and/or efficiency of biomass production from a carbon source, such as e.g. glucose. Processes for generating such microorganisms are also provided by the present invention. The invention also relates to polynucleotide sequences comprising genes that encode proteins that are involved in the bioconversion of a carbon source such as e.g. glucose into biomass. The invention also features polynucleotides comprising the full-length polynucleotide sequences of the novel genes and fragments thereof, the novel polypeptides encoded by the polynucleotides and fragments thereof, as well as their functional equivalents. Also included are processes of using the polynucleotides and modified polynucleotide sequences to transform host microorganisms leading to a microorganism with reduced carbon source diversion, i.e. higher yield and/or efficiency of biomass production from a carbon source such as e.g. glucose.10-13-2011
20110151506Process for Culturing Adherent Cells - The subject of the present invention is a process for producing adherent cells comprising: 06-23-2011
20110250635Method and System for Processing Biomass - A method and system for processing biomass. The method uses an apparatus with a housing, a rotor inside of the housing, and a plurality of protrusions extending from the rotor. The method includes placing the biomass in a fluid medium, inducing cavitation within the fluid to partially separate the biomass, sending the biomass and fluid into the housing, rotating the rotor to further separate the biomass, heating the biomass and fluid, and maintaining the acidity of the fluid and biomass at a pH of between approximately 2 to 6. The system includes apparatus each having a housing and a rotor within the housing. One apparatus has abutting, alternating height protrusions extending from the rotor. Another apparatus has grooves formed in the rotor and an end wall of the housing. Another apparatus has two rows of protrusions extending from the rotor that are spaced apart no less than approximately 6 millimeters.10-13-2011
20110081677Active Microfluidic Membranes - The present invention relates to a biofabricated Active Microfluidic Membrane (AMM) in a microfluidic network of a microfluidic device and a method for the in situ biofabrication of such a microfluidic network. More specifically, the invention relates to devices exhibiting (and methods of) positioning (i.e., erecting, modifying or removing a membrane matrix in situ in a microchannel of a microfluidic network of a microfluidic device. In one embodiment, the membrane comprises a single type of matrix constituent, such as chitosan, alginate, etc. Alternatively, the membrane may be composed of two or more matrix constituents, which may be integrated into one another or layered adjacent to one another.04-07-2011
20100129860Methods of producing the cellulolytic enhancing activity of a polypeptide - The present invention relates to methods of increasing the activity of a polypeptide having cellulolytic enhancing activity, comprising: adding a soluble activating divalent metal cation to a composition comprising the polypeptide having cellulolytic enhancing activity, wherein the presence of the soluble activating divalent metal cation and the polypeptide having cellulolytic enhancing activity increases degradation or conversion of a cellulose-containing material by a cellulolytic enzyme composition compared to the polypeptide having cellulolytic enhancing activity without the soluble activating divalent metal cation. The present invention also relates to compositions, methods for degrading or converting a cellulose-containing material, and methods for producing a fermentation product.05-27-2010
20110151507Solar Biofactory, Photobioreactors, Passive Thermal Regulation Systems and Methods for Producing Products - The invention described herein relates to photobioreactors, methods, assembly and use of such apparatus for culturing light-capturing organisms in a cost-effective manner. Various embodiments provide for a passive thermal regulation system employing selected microorganisms in a photobioreactor apparatus and methods for biological production of various fuel and chemical products from these organisms. Additional embodiments provide a solar biofactory system capable of culturing light capturing organisms to an areal productivity of 3.3 g/m2/hr. Further embodiments are directed to a photobioreactor capable of culturing light capturing organisms to an OD06-23-2011
20110033887Three-Dimensional Microfabricated Bioreactors with Embedded Capillary Network - In an aspect, the present invention uses projection micro stereolithography to generate three-dimensional microvessel networks that are capable of supporting and fostering growth of a cell population. For example, provided is a method of making a microvascularized bioreactor via layer-by-layer polymerization of a photocurable liquid composition with repeated patterns of illumination, wherein each layer corresponds to a layer of the desired microvessel network. The plurality of layers are assembled to make a microvascular network. Support structures having different etch rates than the structures that make up the network provides access to manufacturing arbitrary geometries that cannot be made by conventional methods. A cell population is introduced to the external wall of the network to obtain a microvascularized bioreactor. Provided are various methods and related bioreactors, wherein the network wall has a permeability to a biological material that varies within and along the network.02-10-2011
20110212487Methods for Producing Charcoal and Uses Thereof - The present invention relates to methods for producing activated charcoal from lignocellulose-containing material residual solids and uses of the same.09-01-2011
20110165617Enzymatic Hydrolysis Of Pretreated Lignocellulose-Containing Material With Distillers Dried Grains - A method for producing a fermentation product from a lignocellulose-containing material comprises combining lignocellulose-containing material and distillers dried grains with or without solubles (DDG/S); pre-treating the combined ligno-cellulose-containing material and DDG/S; exposing the pre-treated combined lignocellulose-containing material and DDG/S to an effective amount of hydrolyzing enzyme; and fermenting with a fermenting organism to produce a fermentation product.07-07-2011
20120202242System and Method for Non-Sterile Heterotrophic Algae Growth - A system and method for non-sterile heterotrophic algae growth is provided. The system includes a first Continuous Stirred Tank Reactor (CSTR), kept under sterile conditions, for mixing a full load nutrient with algae cells to create a culture. After being transferred to a first Plug Flow Reactor (PFR), a nutrient is depleted from the culture to create an effluent. By depleting the nutrient, algae cells are able to grow more rapidly without having to compete with other microbes for available nutrients. Once the effluent is created, it is transferred to a second PFR where organic carbon is added. By adding organic carbon, the algae cells grow intracellular oil rapidly. Algae cells are then removed for processing into biofuel.08-09-2012
20110020863BIOREACTOR ASSEMBLY AND ASSOCIATED METHODS - A bioreactor assembly, including: a housing internally defining a plurality of reaction chambers; a medium flow supply line associated with each of the plurality of reaction chambers, wherein the medium flow supply line associated with each of the plurality of reaction chambers is operable for delivering a medium flow to each of the plurality of reaction chambers; and one or more framed membrane cartridges selectively disposed within each of the plurality of reaction chambers, wherein each of the one or more framed membrane cartridges disposed within each of the plurality of reaction chambers is operable for holding a biochemically active material that is reacted when exposed to the medium flow.01-27-2011
20110020862Biological solids processing system and method - The consumption of organic solids with anaerobic digestion to generate usable gases including methane is made more efficient by maintaining the ideal digestion temperature, which is attained by combining the anaerobic digestion process with a halogen digester which produces heat energy and hydrogen gas. With a given biological feedstock four outputs can be generated (methane, hydrogen, electricity, and heat) in the ratio that makes the most economical sense. The process also provides a significant reduction in volume of output solids. The halogen oxidation process can be used on all the anaerobic digester effluent to extract more energy and oxidize a wet feedstock. If there are solids which are not easily digested with the anaerobic process, these solids can be diverted to the halogen digester to derive more energy from the feedstock. Pathogens common to other anaerobic digester effluents are removed. The mixture of methane and hydrogen gas can be compressed to produce an enriched compressed natural gas (CNG) with a variety of uses.01-27-2011
20110053213Polypeptides Having Ferulic Acid Esterase Activity and Polynucleotides Encoding Same - The present invention relates to isolated polypeptides having ferulic acid esterase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.03-03-2011
20110117596COMPOSITE SORBENT MATERIAL, ITS PREPARATION AND ITS USE - A composite sorbent material is disclosed which comprises A) a housing of a dense, insoluble material having openings therein and B) a porous polymer gel housed within said housing, said housing being provided with openings therein for fluid communication between said porous monolithic polymer gel and the surroundings, and said porous monolithic polymer gel occupying the inner space of said housing and being kept on place within said housing by mechanical means. Processes for the preparation of composite sorbent materials by cryoprecipitation are also disclosed as well as the use of the composite sorbent material according to the invention e.g. for the removal of pollutants from gases or liquids, for the enrichment or separation of molecules and for cell culture.05-19-2011
20110136167Variants of glycoside hydrolases - The present invention relates to variants of a parent glycoside hydrolase, comprising a substitution at one or more positions corresponding to positions 21, 94, 157, 205, 206, 247, 337, 350, 373, 383, 438, 455, 467, and 486 of amino acids 1 to 513 of SEQ ID NO: 2, and optionally further comprising a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2 a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2, wherein the variants have glycoside hydrolase activity. The present invention also relates to nucleotide sequences encoding the variant glycoside hydrolases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences.06-09-2011
20110027827INTEGRATED SYSTEM FOR PRODUCTION OF BIOFUEL FEEDSTOCK - Disclosed is a culture system for the production of algae biomass to obtain lipid, protein and carbohydrate. By integrating heterotrophic processes with a phototrophic process in parallel, this system provides year around production in colder climates. By integrating heterotrophic processes with a phototrophic process in series, this system creates a two-stage, separated mixed-trophic algal process that uses organic carbon and nutrients for the production of seed in the heterotrophic process, followed by release of cultured seed in large-scale phototrophic culture for cell biomass accumulation. Organic carbon source including waste materials can be used to feed the heterotrophic process. The production capacity ratio between the heterotrophic and the phototrophic processes can be adjusted according to season and according to the availability of related resources. The systems are used for producing and harvesting an algal biofuel feedstock as well as other potential high-value products. The sequence and approach enhances utilization of carbon and nutrient waste-streams, provides an effective method for controlling contamination, adds flexibility in regard to production and type of available products, and supplies greater economic viability due to maximized use of available growth surface areas.02-03-2011
20100330614GLOBAL TRANSCRIPTION MACHINERY ENGINEERING TARGETING THE RNAP ALPHA SUBUNIT (RPOA) - The invention relates to global transcription machinery engineering to produce altered cells having improved phenotypes.12-30-2010
20100173354METHOD FOR THE FERMENTATION OF ENSILAGED RENEWABLE RAW MATERIALS - A method of fermenting ensilaged renewable raw materials, wherein the method comprises washing and crushing ensilaged renewable raw materials, removing at least some water from the washed and crushed ensilaged renewable raw materials, subjecting the washed and crushed ensilaged renewable raw materials to hydrolysis, and subjecting hydrolysis products to a biogas production method in fermenters07-08-2010
20110033888METHOD FOR PRODUCING SWEET JUICE FROM LIGNOCELLULOSIC BIOMASS WITH IMPROVED ENZYME RECYCLE - The present invention relates to a method of producing sweet juice from lignocellulosic substrate, wherein enzymatic hydrolysis is carried out by performing cellulase supplementation with supported β-glucosidases used in a reactor separate from the lignocellulose enzymatic hydrolysis reactor.02-10-2011
20100159508THERMALLY RESPONSIVE MICELLES - The invention provides an amphiphilic copolymer comprising monomer units derived from a first monomer and monomer units derived from a second monomer. The copolymer has at least one hydrophobic endgroup. The first monomer is such that the copolymer is thermally responsive and the second monomer comprises a carboxylic acid or carboxylate group.06-24-2010
20100021961METHOD FOR PREPARING BIOLOGICAL SCAFFOLD MATERIAL - Disclosed is a method for production of a bio-derived scaffold for use in regenerative medicine, which has a bio-compatibility and biodegradability and can self-organize and grow without causing calcification. The method comprises the steps of partially fixing a biological soft tissue with glutaraldehyde by cross-linking and incubating the partially fixed tissue together with an elastase.01-28-2010
20120040395ENZYME CATALYST IMMOBILIZED ON POROUS FLUOROPOLYMER SUPPORT - Enzyme catalyst immobilized on porous flouropolymer supports. Catalytically active enzymes can be bound to a variety of fluoropolymer supports for use as a reaction catalyst. Moreover, consistently high rate of conversion during catalyst re-use over time is achieved. Furthermore, inactive enzyme catalyst can be stripped from the support and fresh enzyme can be bound to the support to achieve the original conversion rate. The immobilization of catalytic enzymes on porous fluoropolymers is a viable and novel technology for the preparation of advantaged catalysts.02-16-2012
20110306088Mini-Reactor Optimized Channel Sizing - A honeycomb body is disclosed having cells extending along a common direction, a first plurality of the cells being open at both ends of the body and a second plurality of the cells being closed at one or both ends of the body, the second plurality of cells arranged in one or more groups of cells cooperating to define one or more fluid passages extending through the body at least in part perpendicularly to the common direction, wherein, in a plane perpendicular to the common direction, the ratio of the area of cells of the first plurality to the area of cells of the second plurality varies along the length of at least one of the one or more fluid passages.12-15-2011
20100167339PROCESS FOR MICROALGAE CONDITIONING AND CONCENTRATION - Conditioning and concentration of microalgae are accomplished by the process steps of grinding a dilute aqueous dispersion of microalgae in the presence of grinding media and then applying adsorptive bubble separation. This process is amenable to the use of dilute feed microalgal dispersions such as are encountered in the production of algal biomass for biofuel applications.07-01-2010
20110318778Organic Substrate Treatment System - The present invention is directed to an organic substrate treatment system that converts organic substrate and other organic materials to nutrient rich effluent and biogas. Using sequential degradation of the organic materials, biogas and effluent is efficiently produced with relatively short digestion times. Additives are added to the organic materials prior to anaerobic digestion to enhance biogas production. A desulfurizer may be used to clean the raw biogas so that it is suitable for use with gas engines and boilers.12-29-2011
20120003689HYDROPHOBIC MAGNETIC PARTICLES - A process for making a particulate material comprising mesoporous particles having granules of a metal containing species in at least some of the pores thereof, said process comprising: allowing a compound of the metal to enter pores of hydrophobic mesoporous particles, said compound being thermally decomposable at a decomposition temperature to form a metal containing species and said particles being substantially thermally stable at said decomposition temperature; and heating the hydrophobic mesoporous particles having the compound in the pores thereof to the decomposition temperature so as to decompose the compound and to form the mesoporous particles having granules of the metal containing species in at least some of the pores thereof.01-05-2012
20120003688COMPOSITIONS AND METHODS FOR USING NADH OXIDASES - The present disclosure relates generally to bacterial NADH oxidases and, more particularly, to novel NADH oxidases obtained from 01-05-2012
20090104655Fermentation Method and Apparatus for its Implementation - In order to develop and optimize metering strategies for fed-batch fermentations in two or more reaction vessels, release systems containing nutrients are attached to the inner surfaces of the reaction vessels in areas that will come into contact with culture liquid placed in the vessels.04-23-2009
20120058510ENZYME COMPLEX FROM TRICHODERMA REESEI AND P. FUNICULOSUM ENZYMES - The invention relates to an improved enzyme complex having a plurality of enzyme activities of an expression product obtained by fermentation of the genus 03-08-2012
20110086385PROCESS FOR THE PRODUCTION OF BIOGAS - A container (04-14-2011
20110091934Laccase Variants - The present invention relates to variants of a parent laccase. The present invention also relates to polynucleotides encoding the variant laccases and to nucleic acid constructs, vectors, and host cells comprising the polynucleotides, and methods of using the variant enzymes.04-21-2011
20120122152TREATING BIOMASS TO PRODUCE MATERIALS USEFUL FOR BIOFUELS - Fermentable sugar useful for the production of biofuels can be produced from biomass by contacting the biomass with a solution containing at least one α-hydroxysulfonic acid. The α-hydroxysulfonic acid can be easily removed from the product and recycled.05-17-2012
20090130706PHOTOBIOREACTOR SYSTEMS POSITIONED ON BODIES OF WATER - Certain embodiments and aspects of the present invention relate to a photobioreactor including photobioreactor units through which a liquid medium stream and a gas stream flow. The photobioreactor units are floated on a body of water such as a pond or a lake. The liquid medium comprises at least one species of phototrophic organism therein. Certain methods of using the photobioreactor system as part of fuel generation system and/or a gas-treatment process or system at least partially remove certain undesirable pollutants from a gas stream. In certain embodiments, the photobioreactor units are formed of flexible, deformable material and are configured to provide a substantially constant thickness of liquid medium. In certain embodiments, a barrier between the photobioreactor unit and the body of water upon which the unit is floated facilitates thermal communication between the liquid medium and the body of water.05-21-2009
20090130704Novel bioreactor - This invention provides bioreactors having a selectively permeable porous material with an open pore structure, useful for producing products including hydrogen gas, biomass, chemicals, and pharmaceuticals. The porous materials are utilized, for example, as one or more portions of or entire walls, covers, floors, filters, windows, or tubes of the bioreactors. This invention provides bioreactors comprising porous materials that are aerogels, xerogels, or sol-gel glasses, including silica aerogels. The selectively permeable porous materials are gas-permeable, and in addition optionally photopermeable, transparent, hydrophobic, and/or capable of functioning as sterile barriers. This invention provides methods for culturing cells and organisms employing the bioreactors of the invention. This invention further provides methods for producing gaseous products, including hydrogen, biomass, chemicals, and pharmaceuticals employing the bioreactors of the invention.05-21-2009
20100209966ASEPTIC BIOREACTOR SYSTEM FOR PROCESSING BIOLOGICAL MATERIALS - A bioreactor system according to one embodiment of the present invention is provided for producing and processing a biological material in an aseptic environment. For example, the system includes at least one culture tube configured to hold a liquid media containing a biological material and at least one flexible bag for promoting growth of the biological material therein. The liquid media and biological material are configured to be transferred from the culture tube to the flexible bag aseptically in an unclassified area. The system also includes at least one flexible harvest bag configured to be in flow communication with the flexible bag, wherein the flexible harvest bag is configured to separate biological material grown in the flexible bag from the liquid media aseptically in an unclassified area.08-19-2010
20120171718Submerged Perfusion Bioreactor - A device for biological purposes such as cell culturing, enzymatic reactions or filtering of fluid has a body with first and second surfaces. The body is delimited by a rim and an aperture in the center of the body. The aperture is covered at the first and second surface by first and second plates. The first and/or second plate has an inlet orifice allowing liquid medium into the aperture. Rotating means are arranged in the aperture between the first and second plate. At least one recessed portion is a cavity in the rim of the body having a first outlet orifice allowing the liquid medium to flow out of the body. At least one outlet channel connects the circular aperture with the recessed portion. Liquid is pumped into the aperture of the device and pumped through at least one outlet channel.07-05-2012
20100009403Reduced Activity of Ubica in E. Coli - Production of products by engineered bacteria is increased by regulating cellular respiration. Cellular respiration is controlled by reducing electron transfer enzyme activity. Some examples of electron transfer enzymes include NADH dehydrogenases, Succinate dehydrogenases, ubiquinone synthesis, cytochrome O, and cytochrome D. In one example, deletion of UbiCA prevents respiration. Respiration can the be controlled by addition of ubiquinone or expression of ubiCA.01-14-2010
20090061479MINERALIZED THREE-DIMENSIONAL BONE CONSTRUCTS - The present disclosure provides ex vivo-derived mineralized three-dimensional bone constructs. The bone constructs are obtained by culturing osteoblasts and osteoclast precursors under randomized gravity vector conditions. Preferably, the randomized gravity vector conditions are obtained using a low shear stress rotating bioreactor, such as a High Aspect Ratio Vessel (HARV) culture system. The bone constructs of the disclosure have utility in physiological studies of bone formation and bone function, in drug discovery, and in orthopedics.03-05-2009
20100291621ANAEROBIC PROCESS - An anaerobic process uses a continuous oscillatory flow reactor (11-18-2010
20100291620BIO-FUEL PRODUCTION SYSTEM - A biological material production system having an enclosure; a plant advancer located within th enclosure, the plant advancer configured to move one or more plants from a first position to a second position in a predetermined path; and at least one harvester positionable proximate the second position and configured to remove at least a portion of the one or more plants from the plant advancer. A biofuel production system having a biological material production system a harvesting device configured to harvest the biological material as the biological material matures, at least a portion of the harvesting system being substantially within the enclosure, the harvesting system configured to extract liquid from the biological material; a fermenting device proximate the harvesting system and configured to accept and ferment the liquid from the harvesting system; and a distillation device proximate the fermenting device and configured to distill the fermented liquid.11-18-2010
20120225450CARBOXYL-CONTAINING POLYMERS WITH IMPROVED STORAGE STABILITY AND PROCESSABILITY - The present invention relates to carboxyl-containing polymers having higher storage stability and improved processability in the form of powders, pellets or granules and to their use in laundry detergents and cleaners, and also in further fields of use.09-06-2012
20120190062PROCESS FOR THE CONVERSION OF BIOMASS TO LIQUID FUELS AND SPECIALTY CHEMICALS - A process is disclosed for converting biomass to fuels and/or valuable chemicals. The process comprises the steps of a) activating biomass to make it more susceptible to conversion; c) partially converting the biomass to a solubilized material; and d) subjecting the unconverted biomass to a second conversion step. The process optionally comprises a step b) of adding a solvent to the activated biomass. In a preferred embodiment the solubilized biomass obtained in step c) is removed before the unconverted biomass is subjected to step d).07-26-2012
20120264166MULTIFUNCTIONAL BIOMATERIALS AS SCAFFOLDS FOR ELECTRONIC, OPTICAL, MAGNETIC, SEMICONDUCTING, AND BIOTECHNOLOGICAL APPLICATIONS - One-dimensional ring structures from M13 viruses were constructed by two genetic modifications encoding binding peptides and synthesis of a heterobifunctional linker molecule. The bifunctional viruses displayed an anti-streptavidin peptide and hexahistidine (SEQ ID NO:4) peptide at opposite ends of the virus as pIII and pIX fusions. Stoichiometric addition of the streptavidin-NiNTA linker molecule led to the reversible formation of virus-based nanorings with circumferences corresponding to lengths of the packagable DNAs. These virus-based ring structures can be further engineered to nucleate inorganic materials and form metallic, magnetic, or semiconductor nanorings using trifunctionalized viruses.10-18-2012
20120231494COMBINED LIQUID TO SOLID-PHASE ANAEROBIC DIGESTION FOR BIOGAS PRODUCTION FROM MUNICIPAL AND AGRICULTURAL WASTES - Biogas is obtained in a solid-state anaerobic digester from a solid organic biomass and a digestion effluent produced in an associated liquid anaerobic digester. The solid organic biomass and digestion effluent are mixed to produce an effluent-biomass mixture. The effluent-biomass mixture is then incubated in the solid state anaerobic digester, producing a biogas and a digestate. The incubation is controlled by adjusting the composition and properties of the effluent-biomass mixture. The solid organic biomass may comprise lignocellulosic biomass, food waste, agricultural waste and the like.09-13-2012
20110045529METHOD AND GENE FOR PROVIDING OR ENHANCING NONSPECIFIC ADHESIVE PROPERTY AND/OR AUTOAGGLUTINATING PROPERTY FOR MICROORGANISMS - A method for providing or enhancing a nonspecific adhesive property, an autoagglutinating property, or both properties in a microorganism is provided. The method comprises introducing a nucleic acid encoding autotransporter adhesin from a microorganism having a nonspecific adhesion property into a target microorganism.02-24-2011
20110250637METHOD FOR PRODUCING SUGAR LIQUID - A sugar liquid containing only very small amounts of fermentation-inhibiting substances is produced by a method for producing a sugar liquid using a cellulose-containing biomass as a raw material, the method including: (1) a step of hydrolyzing a cellulose-containing biomass to produce an aqueous sugar solution; and (2) a step of filtering the obtained aqueous sugar solution through a nanofiltration membrane and/or reverse osmosis membrane to collect a purified sugar liquid from the feed side, while removing fermentation-inhibiting substances from the permeate side.10-13-2011
20120100572BIOPROCESSING - Bioreactors are provided that include a vessel and a jet mixer disposed in the vessel. Methods that utilize the bioreactors are provided, involving placing a microorganism or cells and a fluid medium in the bioreactor.04-26-2012
20120100571METHODS AND MATERIALS FOR NANOCRYSTALLINE SURFACE COATINGS AND ATTACHMENT OF PEPTIDE AMPHIPHILE NANOFIBERS THEREON - Biocompatible composites comprising peptide amphiphiles and surface modified substrates and related methods for attachment thereon.04-26-2012
20100178669Method for the Intensive Extraction of Cellular Compounds from Micro-Organisms by Continuous Culture and Extraction, and Corresponding Device - HA method is provided for extracting cellular compounds from micro-organisms. The method includes culturing the micro-organisms and extracting the cellular compounds from the micro-organisms. Each step is carried out in a continuous manner, wherein the extraction step is carried out separately from the culture step and in conditions of biocompatibility with the micro-organisms. The method further includes at least one step of recovering the cellular compounds and at least one step of recirculating the micro-organisms towards the culture step.07-15-2010
20080248519Agitator For A Fermenter, Fermenter And Method For Operating A Fermenter - The invention relates to an agitator for a fermenter, a fermenter and method of operating a fermenter.10-09-2008
20080241877Immobilised Enzymes - The present invention relates to a method for immobilizing enzymes in a solid porous support, and to enzymes immobilized in solid porous supports. Specifically, the present invention uses a fluid containing the enzyme under high pressure (such as 25 to 50 Mpa) to immobilize the enzyme (such as CALB) on the porous support (such as silica). The resulting porous support contain more immobilized enzyme than would otherwise have been obtained by a process carried out at atmospheric pressures.10-02-2008
20080213825Hyperbaric Criogenesis Chambers - The Hyperbaric Cryogenesis Chambers are equipment for medical usage, extracorporeal, and capable of promoting the proliferation and preservation of cells in a way mainly microbiologic, “not biologic”. They are compartments with containers that host tissues or cells in solution with nutrients, that bear pressures higher and lower to sea level They have a cold system inside that lowers the environmental temperature and maintains it permanently. They are for maintaining viability of cells or tissues and to induce their organized proliferation with oxygen or other gases at pressures higher or lower that the exterior of the chamber.09-04-2008
20130115654METHOD FOR PRODUCING BIOBASED CHEMICALS FROM AGRICULTURAL BIOMASS - A method for utilizing agricultural biomass components, namely cellulose, hemicellose, and lignin, and converting them to value-added biobased chemical products is described herein. The present method provides treatments to obtain a plurality of component streams from agricultural biomass for producing derivative products while minimizing waste products.05-09-2013
20130115653METHOD FOR PRODUCING BIOBASED CHEMICALS FROM WOODY BIOMASS - A method for utilizing woody biomass components, namely cellulose, hemicellose, and lignin, and converting them to value-added biobased chemical products is described herein. The present method provides treatments to obtain a plurality of component streams from woody biomass for producing derivative products while minimizing waste products.05-09-2013
20130143261METHOD FOR THE UTILIZATION OF VINASSE - In order to counteract comprehensively existing vinasse problems, in particular in production of bioethanol from plant raw materials, a method for production of feedstuff from 06-06-2013
20110275117PHOTOBIOREACTOR SYSTEM WITH HIGH SPECIFIC GROWTH RATE AND LOW DILUTION RATE - Systems and methods for growing photosynthetic cells that may be used to produce a biomass. The systems and methods recycle liquid and can produce a high cell concentration harvested biomass.11-10-2011
20110275116METHODS FOR CONTROL OF FLUX IN METABOLIC PATHWAYS THROUGH ENZYME RELOCATION - Genetically manipulated cells, lysates of such cells, systems, and methods of use thereof are provided, where one or more enzymes in a pathway of interest are genetically modified to incorporate a peptide sequence that provides for relocation of the protein, e.g., to the periplasm, so as to sequester the enzyme, and where the enzyme controls flux in the pathway of interest.11-10-2011
20110312024METHOD OF AND APPARATUS FOR FERMENTING BIOMASS - The invention relates to a method of and an apparatus for fermenting organic material in an apparatus comprising a container. The method includes the steps of feeding organic material and fermenting microbes (12-22-2011
20110312023Integrated Technology of Algae Bio-Diesel and Algae Ferment Reuse - An integrated technology of algae bio-diesel and algae ferment reuse includes providing algae, placing the algae into an optical reactor to grow the algae into rich algae, abstracting the rich algae to form abstracted algae and fat, placing the abstracted algae into a ferment tank so that the abstracted algae are decomposed and fermented to form a fermented substance and a fermented liquid, and making the fermented substance and the fermented liquid into a by-product. Thus, the algae produce carbon dioxide during the fermenting process, so that the carbon dioxide produced by the abstracted algae in the ferment tank is supplied to the algae in the optical reactor to form a breathing cycle between the optical reactor and the ferment tank so as to promote the growth of the algae simultaneously.12-22-2011
20120028299Enzymatic Hydrolysis Of Pretreated Lignocellulose-Containing Material With Dissolved Air Flotation Sludge - A method for producing a fermentation product from a lignocellulose-containing material comprises pretreating the lignocellulose-containing material; introducing treated dissolved air flotation sludge to the pretreated lignocellulose-containing material; exposing the pretreated lignocellulose-containing material to a hydrolyzing enzyme; and fermenting with a fermenting organism to produce a fermentation product.02-02-2012
20120083012Expression System for Producing Multi-Enzyme Complexes and Uses Thereof - An expression system for producing a multi-enzyme complex, the system including a nucleic acid molecule containing a promoter operatively linked to a nucleotide sequence including multiple genes encoding multiple enzymes that are components of the multi-enzyme complex.04-05-2012

Patent applications in class MICRO-ORGANISM, TISSUE CELL CULTURE OR ENZYME USING PROCESS TO SYNTHESIZE A DESIRED CHEMICAL COMPOUND OR COMPOSITION

Patent applications in all subclasses MICRO-ORGANISM, TISSUE CELL CULTURE OR ENZYME USING PROCESS TO SYNTHESIZE A DESIRED CHEMICAL COMPOUND OR COMPOSITION