Entries |
Document | Title | Date |
20080199429 | Cell Bandage - The invention provides a method for delivering cells across the surface of a tissue, the method comprising distributing the cells on and/or within a sheet of biomaterial to form a cell bandage and applying the cell bandage to the surface, wherein, after application of the cell bandage to the surface of the tissue, the cells are released from the cell bandage. Further provided is a method for bonding two or more tissues, the method comprising providing a cell bandage in intimate contact with the surfaces to be joined, wherein the cell bandage comprises a sheet of biomaterial, said biomaterial having cells distributed on and/or within it. Also provided is a cell bandage for use in the methods of the invention. | 08-21-2008 |
20080199431 | Self-Assembling Membranes And Related Methods Thereof - The present invention relates to self-assembling membranes. In particular, the present invention provides self-assembling membranes configured for securing and/or delivering bioactive agents. In some embodiments, the self-assembling membranes are used in the treatment of diseases, and related methods (e.g., diagnostic methods, research methods, drug screening). | 08-21-2008 |
20080206195 | Compositions and Methods for Treating Disorders Associated with Abnormal Phosphate Metabolism - The present invention uncovers that mutations in GALNT3 gene encoding UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T3) cause familial tumoral calcinosis (FTC). Methods and pharmaceutical compositions useful for treating disorders associated with abnormal phosphate metabolism are provided. Specifically, inducers of GalNAc-T3 can be used to treat hyperphosphatemia related disorders such as FTC, and on the other hand, inhibitors of GalNAc-T3 can be used to treat disorders associated with hypophosphatemia, such as hypophosphatemic rickets. The present invention further provides methods and kits for diagnosing familial tumoral calcinosis as well as for identifying agents suitable for treating disorders associated with abnormal phosphate metabolism. | 08-28-2008 |
20080206196 | Differentiation of cord blood into neural like cells, and method to treat neurological condition patients - The invention discloses a method of expansion and differentiation umbilical cord blood cells into neural-like cells in clinic grade, the cell preparation and herein the method for treating neurological condition in human. | 08-28-2008 |
20080247993 | Microorganisms Inhibiting the Formation of Axillary Malodor - Described are microorganisms which are able to suppress the production of malodorous compounds by axillary bacteria. Also described are compositions comprising such microorganisms as well as the use of such micoorganisms in cosmetic, prophylactic or therapeutic applications. | 10-09-2008 |
20080260692 | Spirulin Composition Rich in Active Principles, Method for Obtaining Same and Use Thereof - The invention relates to a spirulina combination composed of at least two distinct strain types from the genus | 10-23-2008 |
20080267919 | ANGIOGENESIS-PROMOTING SUBSTRATE - An angiogenesis-promoting substrate which can be manufactured easily and in reproducible quality and which, in particular, under physiological conditions, remains stable for a specified time and yet is biocompatible and resorbable is provided, comprising a porous shaped body formed from a gelatin-containing material which is insoluble and resorbable under physiological conditions. | 10-30-2008 |
20080279824 | ARTICLES FOR TISSUE REGENERATION WITH BIODEGRADABLE POLYMER - The invention is to articles made from extracellular matrix sheets that encase biodegradable polymeric material. Methods of healing wounds or regenerating tissue at sites of defect by placing said articles in mammals are claimed. The biodegradable polymer can change quality upon contact with a physiological parameter such as temperature or pH that causes, for example, a liquid polymer to gel or harden. The degradation of the polymer can be controlled to suit a tissue regeneration or wound healing time course. Additional components such as proteins, cells and drugs can be added to the biopolymer composition. | 11-13-2008 |
20080286235 | Antimicrobials and related methods - Compositions for antimicrobial, antibacterial, antiviral, fungicidal and sporicidal applications comprise a mixture of alkyl betaine and alkyl amine oxide components together with a protonating agent. The compositions are particularly effective in the treatment and elimination of microorganisms in planktonic cell form as well as in sessile cell form in biofilms. The compositions may be applied in the form of sprays and foams as well as in liquid forms, as a solution or as a balm, as the sole active ingredient or with other active ingredients together with carriers or diluents. | 11-20-2008 |
20080292591 | Tumor mouse models using lentiviral vectors - This invention provides model systems for study of tumors. Model cells and model animals are prepared to mimic characteristics of natural clinical tumors. The tumor models can be contacted with putative modulators to screen for therapeutics and to help understand tumorigenic processes. Model animals can include model cells, closely correlated to the characteristics of clinical tumors, in an environment closely mimicking that of the tumors in patients. Thus, the animal models are highly representative for use in clinical and pharmacological studies. | 11-27-2008 |
20090117078 | CROSSLINKED COMPOUNDS AND METHODS OF MAKING AND USING THEREOF - Described herein are crosslinked compounds useful in numerous treatments. Described herein are methods of making crosslinked compounds via (1) die oxidative coupling of two or more thiol compounds or (2) by the reaction between at least one thiol compound with at least one thiol-reactive compound. | 05-07-2009 |
20090117079 | METHODS AND MATERIALS FOR TREATING OR PREVENTING DISEASES/DISORDERS MEDIATED BY ALCOHOL DEHYDROGENASE - The present disclosure relates generally to methods and materials for treating and/or preventing a disease or disorder in a subject that is mediated by alcohol dehydrogenase by administering to the subject a therapeutically effective amount of one or more agents that prevents and/or inhibits the metabolism of methanol by alcohol dehydrogenase. Methanol metabolism may be reduced/inhibited in a subject by administering to the subject a therapeutically effective amount of ethanol. | 05-07-2009 |
20090186001 | Methods for Treating Ischemic Tissue - Compositions and methods for treating ischemic tissue are provided herein. | 07-23-2009 |
20090214475 | Extractability and Bioavailability of the Natural Antioxidant Astaxanthin From a Green Alga, Haematococcus Pluvialis - As the richest source of astaxanthin, a natural antioxidant and coloring agent, the unicellular green alga, | 08-27-2009 |
20090304635 | Methods for generating new hair follicles, treating baldness, and hair removal - The present invention provides methods of treating baldness in a subject and generating new hair follicles, comprising epidermal disruption and administration of a compound that promotes a differentiation of an uncorαmitted epidermal cell into a hair follicle cell. The present invention also provides methods for hair removal and inducing hair pigmentation. | 12-10-2009 |
20100111903 | COMPOSITIONS PRODUCED USING ENTERIC PATHOGENS AND METHODS OF USE - The present invention provides compositions including polypeptides having the characteristics of polypeptides expressed by a reference microbe such | 05-06-2010 |
20100119485 | NOVEL METHOD FOR BIOLOGICALLY COMBATING THE PROLIFERATION OF LEGIONELLA PNEUMOPHILA, AND NOVEL DISINFECTING AGENT CONTAINING AMOEBIC PROTOZOA OF THE WILLAERTIA GENUS - The invention relates to a method for biologically combating the proliferation of | 05-13-2010 |
20100150870 | METHOD FOR IMPROVING THE SKIN AND COAT OF PETS - A method for improving or maintaining the skin and coat system of a pet includes administering to the pet a nutritional agent which promotes the growth of bifido- and lactic-bacteria in its gastro-intestinal tract. The nutritional agent may be a prebiotic or a probiotic micro-organism, or both. The nutritional agent may be administered together with a long chain fatty acid. | 06-17-2010 |
20100196322 | POLYMER FOR TISSUE ENGINEERING APPLICATIONS AND DRUG DELIVERY - A biocompatible and biodegradable elastomeric polymer material, the polymer material comprising: glycerol and dodecanedioic acid, wherein the molar ratio of glycerol to dodecanedioic acid is from about 5:1 to about 1:5. Methods for using the biocompatible and biodegradable elastomeric polymer material comprises providing an PGD elastomeric polymer comprising glycerol and dodecanedioic acid, in a molar ratio of glycerol to dodecanedioic acid of about 1:1 and administering the PGD elastomeric polymer to a soft tissue defect site in needs thereof. | 08-05-2010 |
20100221224 | COMPOSITION AND METHOD FOR SELF-ASSEMBLY AND MINERALIZATION OF PEPTIDE-AMPHIPHILES - The present invention is directed to a composition useful for making homogeneously mineralized self assembled peptide-amphiphile nanofibers and nanofiber gels. The composition is generally a solution comprised of a positively or negatively charged peptide-amphiphile and a like signed ion from the mineral. Mixing this solution with a second solution containing a dissolved counter-ion of the mineral and/or a second oppositely charged peptide amphiphile, results in the rapid self assembly of the peptide-amphiphiles into a nanofiber gel and templated mineralization of the ions. Templated mineralization of the initially dissolved mineral cations and anions in the mixture occurs with preferential orientation of the mineral crystals along the fiber surfaces within the nanofiber gel. One advantage of the present invention is that it results in homogenous growth of the mineral throughout the nanofiber gel. Another advantage of the present invention is that the nanofiber gel formation and mineralization reactions occur in a single mixing step and under substantially neutral or physiological pH conditions. These homogeneous nanostructured composite materials are useful for medical applications especially the regeneration of damaged bone in mammals. This invention is directed to the synthesis of peptide-amphiphiles with more than one amphiphilic moment and to supramolecular compositions comprised of such multi-dimensional peptide-amphiphiles. Supramolecular compositions can be formed by self assembly of multi-dimensional peptide-amphiphiles by mixing them with a solution comprising a monovalent cation. | 09-02-2010 |
20100239533 | Thraustochytrids, Fatty Acid Compositions, and Methods of Making and Uses Thereof - The present invention is directed to isolated thraustochytrid microorganisms as well as strains and mutants thereof. The invention is further directed to biomasses, microbial oils, compositions, cultures, methods of producing microbial oils, and methods of using the isolated thraustochytrids, biomasses, and microbial oils. | 09-23-2010 |
20100266544 | NON-TOXIC CROSSLINKING REAGENTS TO RESIST CURVE PROGRESSION IN SCOLIOSIS AND INCREASE DISC PERMEABILITY - A method of improving the resistance of collagenous tissue to mechanical degradation in accordance with the present invention comprises the step of contacting at least a portion of a collagenous tissue with an effective amount of a crosslinking reagent. Methods and devices for enhancing the body's own efforts to stabilize discs in scoliotic spines by increasing collagen crosslinks. This stability enhancement is caused by reducing the bending hysteresis and increasing the bending stiffness of scoliotic spines, by injecting non-toxic crosslinking reagents into the convex side of discs involved in the scoliotic curve. Alternatively, contact between the tissue and the crosslinking reagent is effected by placement of a time-release delivery system directly into or onto the target tissue. Methods and devices that use crosslinking agents for increasing the permeability of an intervertebral disc, improving fluid flux to the intervertebral disc, and increasing the biological viability of cells within the intervertebral disc are provided. | 10-21-2010 |
20100278780 | Grass Endophyte Enhanced Attributes - Described is the method and use of AR584 endophyte (AGAL deposit no. NM98/04676 dated 12 May 1998) or variations in endophyte as exemplified by AR584, to produce a grass cultivar and AR584 combination wherein the plant or a part thereof produced by the combination retains viable AR584 endophyte after treatment with fungicide and/or after being subjected to elevated temperature or humidity. | 11-04-2010 |
20100297082 | WEIGHT-BEARING POLYURETHANE COMPOSITES AND METHODS THEREOF - Present inventions present composites of particles and polymers, as well as methods of making such composite and uses thereof. A low or non-porous composite comprises a plurality of bone particles; and polyurethane components with which the bone particles are combined. Provided composites can be prepared in a one-shot process. Alternatively or additionally, composites can be prepared by compression molding under a high pressure. Before or after implantation, provided composites may be set to form a hardened state of composites that provides mechanical strength and supports the in-growth of cells. | 11-25-2010 |
20100330036 | MARKERS OF MATRIX GENE EXPRESSION AND CELLULAR DIFFERENTIATION IN CHONDROCYTES - The invention relates generally to the field of tissue engineering. More particularly, the present invention relates to methods for identifying a population of cells suitable for the repair of connective tissue, including cartilage. The invention further provides methods and compositions related to the generation of a population of cells suitable for the repair of cartilage, in particular in the repair of cartilage degeneration associated with osteoarthritis. Methods of using said cells thus identified or thus generated, in methods to extend the period of cell manipulation, i.e. to increase the yield of cells suitable in the aforementioned methods, are also provided by the present invention. | 12-30-2010 |
20110020281 | Methods for Treating a Plant Exposed to a Phytotoxicant - Methods of treating a plant exposed to a phytotoxicant are provided. Embodiments of the subject methods include identifying a plant exposed to a phytotoxicant and applying an assimilable carbon-skeleton energy component-comprising composition to the identified plant. Embodiments of the subject compositions may include one or more of a macronutrient component, micronutrient component, vitamin/cofactor component, complexing agent and microbe. Kits for use in practicing the subject invention are also provided. The subject methods find use in a variety of different applications in which a plant is phytotoxic or at least in danger of becoming phytotoxic due to exposure or potential exposure to a phytotoxicant. | 01-27-2011 |
20110027230 | COMPOSITIONS COMPRISING PHYTOESTROGENES SELECTIVE FOR ESTROGEN BETA RECEPTOR AND DIETARY FIBRES - Oral compositions comprising an association of one or of a mixture of phytoestrogens, selective for the estrogen receptor-β, with dietary fibres are described. The compositions thereof can be profitably used for the prophylactic and therapeutic treatment in mammals, including humans, of health conditions characterised by a high risk of onset and recurrence of intestinal adenomas (adenopolyposis coli), and of adenoma's progression to colorectal carcinoma. In presence of pre-cancerous lesions in the colon, characterised by mutations of the APC tumor suppressor and defined as polyps or adenomas, the oral compositions disclosed can be in fact profitably used to reduce the number and volume of polyps, and to prevent their progression to neoplastic transformation, reducing their degree of dysplasia. | 02-03-2011 |
20110070198 | Plant-based biocidal materials and systems - The present invention is directed to a method and a composition for producing and using a plant-based biocidal solution. The plant-based biocidal solution contains a bioactive material and a plant-based substance formed from the cellular material of a plant. The plant-based substance is capable of binding to the bioactive material. In some embodiments, the bioactive material is hydrogen peroxide. The hydrogen peroxide can be added exogenously or generated endogenously. In accordance with further embodiments, the plant-based biocidal solution can be applied to a target, thereby impairing the target. In some embodiments, the target can be a pathogen. In accordance with another embodiment, the plant-based substance of the plant-based biocidal solution can form a microscopic cluster, a complex, or an aggregate for providing sufficient bioactive material to overcome the defense mechanism of the target. | 03-24-2011 |
20110076252 | COMPOUND AND METHOD FOR TREATMENT OF GASTROESOPHAGEAL REFLUX - The invention relates to the use of a L-theanine for the treatment of gastroesophageal reflux disease (e.g., heart-burn) in a human or animal, including useful methods and compositions. | 03-31-2011 |
20110091424 | ORAL DOSAGE COMPOSITION - The present invention is an oral dosage composition for prevention and treatment of hepatic inflammation such as NASH. The present invention is an oral dosage composition for prevention or treatment of hepatic inflammation, contains the radical scavenging active spirulina powder effective in preventing, ameliorating, and curing NASH or the like. | 04-21-2011 |
20110165125 | METHODS FOR ENHANCING ENERGY METABOLISM - The invention provides methods for one or more of enhancing energy metabolism, promoting healthy energy metabolism, maintaining healthy energy metabolism, preventing conditions that result in a decline or deficiency in energy metabolism, treating conditions that result in a decline or deficiency in energy metabolism, and preventing the accumulation of excess body fat in animals without reducing energy intake by the animals. The methods comprise administering isoflavones to the animals, preferably in amounts of from about 0.001 to about 10 g/kg/day. | 07-07-2011 |
20110177031 | Eicosapentaenoic Acid-Producing Microorganisms, Fatty Acid Compositions, and Methods of Making and Uses Thereof - The present invention is directed to isolated microorganisms as well as strains and mutants thereof, biomasses, microbial oils, compositions, and cultures; methods of producing the microbial oils, biomasses, and mutants; and methods of using the isolated microorganisms, biomasses, and microbial oils. | 07-21-2011 |
20110200559 | METHOD FOR PRODUCTION OF THREE-DIMENSIONAL STRUCTURE OF CELLS - The present invention provides a method for arranging various cells as cell clusters in an arbitrary three-dimensional space and producing a three dimensional structure of a desired shape constituted exclusively by cells. Furthermore, the present invention provides a support provided with a substrate and a thread or needle-shaped material that penetrates the substrate and cell clusters for positioning cell clusters in arbitrary space. The support is provided with a sheet that can be removed as necessary for covering the substrate. Further, a method for using the support structure to position cell clusters in an arbitrary space and a method for the production of three-dimensional cell structures are provided. | 08-18-2011 |
20110200560 | NON-IONIC SELF-ASSEMBLING PEPTIDES AND USES THEREOF - The invention relates to a novel class of non-ionic, self-assembling peptides, compositions thereof, methods for the preparation thereof and methods of use thereof. | 08-18-2011 |
20110250178 | COSMETIC COMPOSITIONS COMPRISING MICROALGAL COMPONENTS - The invention provides cosmetic compositions comprising microalgal biomass, whole microalgal cells, and/or microalgal oil in combination with one or more other cosmetic ingredients, and methods of making such compositions. In preferred embodiments, the microalgal components of the cosmetic compositions are derived from microalgal cultures grown heterotrophically and which comprise at least 10% oil by dry weight. | 10-13-2011 |
20110256100 | SECRETED MODULAR CALCIUM BINDING PROTEIN FOR INTRACELLULAR MODULATION OF BONE MORPHOGENETIC PROTEIN SIGNALING - A method for modulating Bone Morphogenetic Protein (BMP) signaling activity in a cell or tissue of a vertebrate subject is provided which comprises administering a polynucleotide or polypeptide encoding a Secreted Modular Calcium Binding Protein (SMOC) polypeptide, or a conservatively modified variant, derivative, or analog thereof, in an amount effective to activate intracellular Mitogen Activated Protein (MAP) kinase activity and to reduce BMP signaling activity in the cell or tissue of the vertebrate subject. Methods for treating joint disorders in a mammalian subject are provided. | 10-20-2011 |
20110280834 | METHODS AND COMPOSITIONS FOR CARDIAC TISSUE REGENERATION - Methods for treating an injured cardiac tissue in a subject are provided herein. Methods for improving survival, engraftment and proliferation of stem cells in a cardiac tissue are provided. Also provided are methods for generating cardiac cells. Further provided are compositions for generating cardiac cells in a subject. | 11-17-2011 |
20110300106 | THERAPEUTIC AMOEBA AND USES THEREOF - The present invention relates to amoebae (slime molds) and uses thereof. In particular, the present invention relates to the use of amoebae or their environmentally stable spores to treat microbial infections and other uses. | 12-08-2011 |
20110311486 | 1,2,4-OXADIAZOLE BENZOIC ACID COMPOSITIONS - Novel 1,2,4-oxadiazole benzoic acid compounds, methods of using and pharmaceutical compositions comprising an 1,2,4-oxadiazole benzoic acid derivative are disclosed. The methods include methods of treating or preventing a disease ameliorated by modulation of premature translation termination or nonsense-mediated mRNA decay, or ameliorating one or more symptoms associated therewith. | 12-22-2011 |
20120009152 | NITRIC OXIDE DONORS FOR TREATMENT OF DISEASE AND INJURY - A method of promoting neurogenesis by administering a therapeutic amount of a phosphodiesterase inhibitor compound to a patient in need of neurogenesis promotion. A compound for providing neurogenesis having an effective amount of a phosphodiesterase inhibitor sufficient to promote neurogenesis. A phosphodiesterase inhibitor for promoting neurogenesis. A method of augmenting the production of brain cells and facilitating cellular structural and receptor changes by administering an effective amount of a phosphodiesterase inhibitor compound to a site in need of augmentation. A method of increasing both neurological and cognitive function by administering an effective amount of a phosphodiesterase inhibitor compound to a patient. | 01-12-2012 |
20120027724 | METHODS OF TREATING IMPAIRED GLUCOSE METABOLISM VIA ADMINISTRATION OF ALGAL BIOMASS - The invention is directed to methods of using | 02-02-2012 |
20120039851 | USE OF ANDROGENS FOR VASCULAR REGENERATION AND ENDOTHELIAL REPAIR - The present invention relates to the field of therapy and prophylaxis of vascular tissue damage and/or complications and/or disease of vascular tissue by vascular regeneration and endothelium repair. The inventors have found that administration of an androgen receptor agonist alleviates one or more adverse vascular diseases and/or vascular complications thereof or adverse effects of androgen deficiency, with implications for prophylactic and therapeutic interventions. | 02-16-2012 |
20120045416 | Nutritional therapy method and dietary supplement food to restore compromised, ileal lymphoid nodular hyperplasia in autistic children - A nutritional therapy method to restore mesolimbic compromised, ileal lymphoid nodular hyperplasia in autistic children includes: dietary restriction of casein, gluten, opiatic peptides and branched chain amino acid and the herein described nutritional therapy solution of specified composition to rebalance parasympathetic pathways over sympathatic neural responses to retain and restore digestive, immune and endocrine function, reduce metal uptake across the blood-brain barrier, reduce Ig response, and rectal and gastrointestinal inflammation and dysfunction. | 02-23-2012 |
20120093771 | METHOD FOR PREPARING A HARDENED CALCIUM SULFATE DIHYDRATE BLOCK AND USE THEREOF - The present invention provides a technique for prolonging the working time and setting time of a calcium sulfate hemihydrate paste by mixing calcium sulfate hemihydrate powder with an aqueous solution containing phosphate ions, so that the paste is suitable for operation and the resultant hardened calcium sulfate dihydrate block from the paste has an improved mechanical strength. | 04-19-2012 |
20120100106 | COLLAGEN-BINDING SYNTHETIC PEPTIDOGLYCANS FOR WOUND HEALING - Methods and compositions for promoting wound healing in a patient by administering a collagen-binding synthetic peptidoglycan to the patient are described. Additionally, methods and compositions are described for decreasing scar formation in a patient by administering a collagen-binding synthetic peptidoglycan to the patient. | 04-26-2012 |
20120121542 | RED-SHIFTED OPSIN MOLECULES AND USES THEREOF - The invention, in some aspects relates to compositions and methods for altering cell activity and function and the use of light-activated ion pumps (LAIPs). | 05-17-2012 |
20120141417 | Collagen Preparation and Method of Isolation - Collagen compositions, methods for preparing those collagen compositions, and graft compositions formed from those collagen compositions are provided. In particular, methods of isolating collagen that exhibits an enhanced rate of polymerization and enhanced microstructural and mechanical properties upon polymerization, such collagen compositions, and graft compositions formed from such collagen compositions are provided. | 06-07-2012 |
20120183500 | ARTICLES AND METHODS INCLUDING STABLE THERMALLY-RESPONSIVE POLYMERS - Embodiments of the invention can include or be used in conjunction with implantable medical devices and various in vitro applications. In an embodiment, an implantable medical device is included herein. The device can include a frame having an inner lumen; the frame comprising a copolymer formed from monomers comprising N-isopropylacrylamide or a thermally responsive derivative thereof and a second monomeric species including one or more of a heteroatom or a charged moiety. In an embodiment, a method of isolating a component of a mixture is included herein. The method can include mixing a sample with a copolymer formed from monomers comprising N-isopropylacrylamide or a thermally responsive derivative thereof and a second monomeric species including one or more of a heteroatom or a charged moiety to form a reagent mixture, the copolymer further comprising a moiety exhibiting affinity for an analyte in the sample. The method can further include raising the temperature of the reagent mixture to high enough for the copolymer to form a hydrogel. Other embodiments are also included herein. | 07-19-2012 |
20120183501 | NOVEL METHOD FOR TREATMENT OF SKIN WOUNDS AND PREPARATIONS FOR IMPLEMENTATION OF SAME - Method for treatment of skin wounds, in a patient needing it, in which an effective amount of an insoluble globin preparation is placed in direct contact with the skin wound, the preparation is kept in place for at least one week, without having to change or wash the wound during said time and without a local infection, which would be detrimental to the patient. | 07-19-2012 |
20120189581 | USE OF TOXOPLASMA AND DERIVED COMPOSITIONS TO PREVENT OR TREAT MICROBIAL INFECTIONS - The invention provides a composition comprising an amount of a live attenuated or avirulent | 07-26-2012 |
20120207710 | NUTRITIONAL SUPPLEMENT TO IMPROVE SUPPLEMENTARY TARGET PROTEIN FRACTION (TPF) DELIVERY, INTRACELLULAR ABSORPTION AND UTILIZATION - A nutritional supplement includes the primary ingredients: N-acetyl D-glucosamine, cracked cell wall Green Chlorella, Licorice Root Extract, and Potassium Citrate, as well as secondary ingredients: Zinc L-Carnosine, Gamma-Oryzanol and Capsaicin, that improves the bodies uptake, utilization and over-all bioavailability of exogenous target protein fractions (TPF) including but not limited to: glycoproteins, (such as glucosamine) protein isolates as amino acids, glycosaminoglycans (GAG) (including proteoglycans, and mucopolysaccharides), and polysaccharides such as hyaluronic acid (hyaluronan). The biochemical interactions of the composition improves zeta potential for TPF incorporation in the body through direct and indirect interaction with primary cellular and digestive sites of multiple species. This facilitates greater passage of target protein substrates fractions and isolates into the bloodstream, provides superior intracellular absorption and utilization thereby potentiating the therapeutic effects of TPF systemically. | 08-16-2012 |
20120219525 | STABLE THICKENER FORMULATIONS - Stable thickener formulations and nutritional compositions having the stable thickener formulations are provided. In a general embodiment the present disclosure provides a stable thickener formulation comprising from about 0.015% to about 0.05% by weight of carrageenan and from about 1.2% to about 4.0% by weight of starch. The stable thickener formulation can be used in nutritional compositions used to treat a variety of physiological conditions. | 08-30-2012 |
20120225034 | AGENTS USEFUL IN TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY - The invention teaches antisense agents and RNA interference agents useful for treating diseases and conditions the treatment of which can benefit from reducing the expression of double homeobox 4 and/or double homeobox 4c, more particularly facioscapulohumeral muscular dystrophy. Further elaborated are methods, uses and further products employing such agents. | 09-06-2012 |
20120225035 | ANTIFUNGAL MIXTURE WITH FUNGAL ORGANISM PYTHIUM OLIGANDRUM - The antifungal mixture is designed for fighting human diseases and animal diseases of fungal, bacterial or other origin and for violation of bio-films on heterogeneous materials used both in human and veterinary medicine and for elimination of microflora from various objects coming in contact with humans or animals. The antifungal mixture uses the active component of the fungal organism Pvthium oligandrum in the mixture with inert components; the said antifungal mixture contains 0.001 to 25 weight portions of the fungal organism Pythium oligandrum and 75 to 99.999 weight portions of inert components. The activity of the fungal organism Pythium oligandrum in the mixture arises at the moment when this organism gets in touch with humidity. | 09-06-2012 |
20120225036 | PLANKTON STRAIN ALGAE PARACHLORELLA NUREKIS 1904 KIEG AND HIS USE TO EXTERMINATE CYANOBACTERIA, BACTERIA AND FUNGI - An industrial strain of a unicellular green algae | 09-06-2012 |
20120288478 | COSMETIC COMPOSITIONS - Disclosed are compositions and methods for their use that can be used in cosmetic applications. The composition can include an effective amount of a | 11-15-2012 |
20120301432 | NOVEL BOSWELLIA LOW POLAR GUM RESIN EXTRACT AND ITS SYNERGISTIC COMPOSITIONS - The present disclosure describes | 11-29-2012 |
20130004460 | SILYLATED BIOMOLECULES - The invention concerns: a silylated biomolecule having the following formula (I): the process for the preparation of a silylated biomolecule of formula (I), the use of a silylated biomolecule of formula (I) to functionalize the surface of a support, a process for the preparation of a hydrogel by use of a silylated biomolecule of formula (I), the hydrogel obtainable by said process, said hydrogel as a biological tissue substitute, a composition comprising said hydrogel in a pharmaceutically acceptable vehicle, said composition for the release of active principle. | 01-03-2013 |
20130017173 | NOVEL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE AND AIRWAY INFLAMMATION - Provided are compositions and methods for treating inflammation due to an immune response. Non-limiting example compositions include class-2 SPATE proteins that are capable of cleaving proteins involved in an inflammatory immune response in a patient. Example compositions include at least one mucin-cleaving class-2 SPATE protein. Further example compositions include protein involved in intestinal colonization (Pic). Non-limiting example methods include methods of decreasing inflammation in a patient having inflammation and methods of perturbing immune response in a patient having a disease or condition in which an active immune response is attributable to a cause of the disease or condition, by administering to the patient a composition including at least one class-2 SPATE protein capable of cleaving proteins involved in an inflammatory immune response. | 01-17-2013 |
20130045182 | Polysaccharide Based Hydrogels - Polysaccharide based hydrogel compositions and methods of making and using the same are provided. The subject polysaccharide based hydrogel compositions are prepared by combining a polysaccharide component with a hydrophilic polymer and a cross-linking agent. Also provided are kits and systems for use in preparing the subject compositions. | 02-21-2013 |
20130045183 | BOSWELLIA OIL, ITS FRACTIONS AND COMPOSITIONS FOR ENHANCING BRAIN FUNCTION - The present disclosure relates to non-acidic extracts or fractions selected from a | 02-21-2013 |
20130089521 | USE OF PHOTOSYNTHETIC SCAFFOLDS IN TISSUE ENGINEERING - The present invention is concerned with a photosynthetic scaffold that delivers oxygen and its uses for tissue engineering and the treatment of ischemia. | 04-11-2013 |
20130095070 | USE OF CHICORIC ACID AND DERIVATIVES FOR REGULATING SKIN PIGMENTATION - The present invention relates generally to the field of food supplements for cosmetic purpose. More specifically, the present invention aims to provide an ingredient containing chicoric acid and/or derivatives for preventing and/or treating hyper-pigmentation of skin, skin color imperfections such as age-spots and other skin disorders characterized by abnormal pigments. The present invention also aims at improving skin tone as well as providing a skin lightening agent. | 04-18-2013 |
20130101556 | USE OF CAFTARIC ACID AND DERIVATIVES IN FOOD SUPPLEMENT FOR REGULATING SKIN PIGMENTATION - The present invention relates generally to the field of food supplements and/or food products for cosmetic purpose. More specifically, the present invention aims to provide an ingredient containing caftaric acid and/or derivatives for preventing and/or treating hyper-pigmentation of skin, skin color imperfections such as age-spots and other skin disorders characterized by abnormal pigments. The present invention also aims at improving skin tone as well as providing a skin lightening agent. | 04-25-2013 |
20130209404 | Treatment of IBD and IBS Using Both Probiotic Bacteria and Fermented Cereal as Treatment Effectors - The invention covers a novel treatment strategy that considerably improves conventional probiotic treatments of inflammatory bowel diseases, irritable bowel syndrome and other gastrointestinal disorders. Both probiotic microorganisms and the carrier of the probiotic microorganisms in form of a fermented cereal gruel are used as treatment effectors. Phospholipids may also be an effector. The novel treatment strategy is capable of removing the symptoms of inflammatory bowel diseases regardless of a mild, moderate or severe stage of the disease. | 08-15-2013 |
20130230491 | COVALENTLY IMMOBILIZED PROTEIN GRADIENTS IN THREE-DIMENSIONAL POROUS SCAFFOLDS - The invention provides a method for forming an immobilized agent gradient within a 3-dimensional porous scaffold. A 3-dimensional scaffold formed from a biocompatible material is provided. The surface of the scaffold and/or the agent is activated so as to allow binding of the agent to the scaffold. The activated scaffold is contacted with a solution containing the agent. Contact with the solution is maintained for a sufficient period of time to allow diffusion of the solution through a portion of the scaffold, thereby forming a desired gradient of the agent through the 3-dimensional scaffold. | 09-05-2013 |
20130287735 | HIGH POROSITY MATERIALS, SCAFFOLDS, AND METHOD OF MAKING - Materials and methods for preparing three dimensional scaffolds are described. The materials, as improved high internal phase emulsions (HIPES), and the polymerization thereof may be suitable for injection prior to curing and when in an injectable form may be for site-directed in vivo use, curing after injection. In addition, said materials before curing may be engineered as a tissue substitution or enhancement and/or to include cell encapsulation. Said materials described herein form a monolith after curing and are biodegradable and porous after curing. Said materials are made from starting molecules using a process that does not rely on toxic solvents or monomers. Making of said materials to form the emulsion take advantage of one or more surfactants for HIPE stability. In addition, said materials cure at temperatures appropriate for use in an in vivo or in situ environment. | 10-31-2013 |
20140017200 | MODIFIED TWO-COMPONENT GELATION SYSTEMS, METHODS OF USE AND METHODS OF MANUFACTURE - Compositions, methods of manufacture and methods of treatment for post-myocardial infarction are herein disclosed. In some embodiments, the composition includes at least two components. In one embodiment, a first component can include a first functionalized polymer and a substance having at least one cell adhesion site combined in a first buffer at a pH of approximately 6.5. A second component can include a second buffer in a pH of between about 7.5 and 9.0. A second functionalized polymer can be included in the first or second component. In some embodiments, the composition can include at least one cell type and/or at least one growth factor. In some embodiments, the composition(s) of the present invention can be delivered by a dual bore injection device to a treatment area, such as a post-myocardial infarct region. | 01-16-2014 |
20140030227 | THERAPEUTIC AMOEBA AND USES THEREOF - The present invention relates to amoebae (slime molds) and uses thereof. In particular, the present invention relates to the use of amoebae or their environmentally stable spores to treat microbial infections and other uses. | 01-30-2014 |
20140037582 | Feed Additive Composition - A method for improving the performance of a subject or for improving digestibility of a raw material in a feed (e.g. nutrient digestibility, such as amino acid digestibility), or for improving nitrogen retention, or for improving dietary phosphorus absorption and retention, or for improving the efficacy of the phytase, or for improving the subject's resistance to necrotic enteritis or for improving feed conversion ratio (FCR) or for improving weight gain in a subject or for improving feed efficiency in a subject or for modulating (e.g. improving) the immune response of the subject or for reducing populations of pathogenic bacteria in the gastrointestinal tract of a subject, or for reducing nutrient excretion in manure, which method comprising administering to a subject at least one direct fed microbial in combination with a phytase, wherein the phytase is administered to the subject at a dosage of more than about 1500 FTU/kg feed. | 02-06-2014 |
20140037583 | METHODS AND COMPOSITIONS SUITABLE FOR PREVENTING AND TREATING HYPERLEPTINEMIA - The invention provides methods and compositions suitable for preventing and treating hyperleptinemia, preventing and treating insulin resistance, preventing and treating cardiovascular disease, preventing and treating obesity, preventing and treating hyperlipidemia, and preventing and treating hypertension in an animal. The methods comprise administering one or more isoflavones to the animal, preferably in amounts of from about 0.001 to about 10 g/kg/day. | 02-06-2014 |
20140056850 | DICTYOSTELID AMOEBA AND BIOCONTROL USES THEREOF - The present invention relates to Dictyostelids myxamoebae of phylum Mycetozoa and uses thereof. In particular, the present invention relates to the use of amoebae, slugs, or their environmentally stable spores to treat microbial infections and other uses. | 02-27-2014 |
20140056851 | METHODS FOR MANAGING WEIGHT LOSS AND BODY MASS - The invention provides methods for promoting weight loss by an animal, promoting weight loss by an animal while preventing or minimizing loss of lean body mass by the animal preventing a reduction in energy metabolism by an animal reducing the risk of regaining weight by an animal after weight loss, and ameliorating undesirable animal behaviors associated with reduced caloric intake by intermittently feeding an animal a first diet containing calories that meet the animal's maintenance energy requirements and a second diet containing calories that do not meet the animal's maintenance energy requirements. In preferred embodiments, the described feeding pattern and diets are ted in conjunction with one or more weight loss agents. | 02-27-2014 |
20140086874 | BIOMATERIAL, METHOD FOR MAKING THE BIOMATERIAL AND USES OF THE SAME - A method for making a biomaterial comprising providing at least one polypeptide fraction chymotryptically isolated and extracted from fibroin, and adding the at least one extracted polypeptide fraction to a hydrogel precursor before gelling, wherein the at least one isolated and extracted polypeptide fraction is selected from a soluble fraction Cs, and a precipitated fraction Cp. A biomaterial comprising at least one of the isolated and extracted polypeptide fractions incorporated in a hydrogel or a hydrogel precursor. Use of the biomaterial for constructing, regenerating, repairing, replacing or augmenting soft or hard tissue; as an in vitro or in vivo construct; as a coating material; or as a cell, molecule or particle delivery medium. Use of the isolated and extracted polypeptide fraction Cs for promoting osteoinduction, osteoconduction or osteogenesis. Use of the isolated and extracted polypeptide fraction Cp for enhancing a mechanical compressive modulus of a material into which it is incorporated. | 03-27-2014 |
20140120062 | THREE-DIMENSIONAL POROUS BIODEGRADABLE CELL SCAFFOLD - Disclosed are composites comprising water-soluble polymeric fibers dispersed in a biodegradable polymer matrix, as well as methods of making and using such composites. | 05-01-2014 |
20140147416 | ENGINEERING THE PRODUCTION OF A CONFORMATIONAL VARIANT OF OCCIDIOFUNGIN THAT HAS ENHANCED INHIBITORY ACTIVITY AGAINST FUNGAL SPECIES - Occidiofungin is a cyclic nonribosomally synthesized antifungal peptide with submicromolar activity. This invention is directed to compositions enriched for particular occidiofungin diastereomers/conformers, methods of making compositions enriched for particular diastereomers/conformers and microorganisms suitable for producing enriched compositions of particular diastereomers/conformers. Methods of treating fungal infections or plants infected by fungi are also provided. | 05-29-2014 |
20140154212 | CROSSLINKED GELATIN HYDROGELS - Hydrogels based on gelatin crosslinked with N,N′-methylenebisacrylamide (MBA) are disclosed. The hydrogels according to the invention are useful for cell culture, growth and proliferation, for the controlled release of bioactive molecules, and to promote tissue regeneration. | 06-05-2014 |
20140199265 | NUTRITIONAL COMPOSITIONS CONTAINING A NEUROLOGIC COMPONENT AND USES THEREOF - The present disclosure relates to nutritional compositions comprising a neurologic component, wherein, the neurologic component may promote brain and nervous system development and further provide neurological protection and repair. The neurologic component may include phosphatidylethanolamine, sphingomyelin, cytidine diphosphate-choline, ceramide, uridine, at least one ganglioside, and mixtures thereof. The disclosure further relates to methods of promoting brain and nervous system health by providing said nutritional compositions to target subjects, which includes pediatric subjects. | 07-17-2014 |
20140199266 | HONEY NASAL RINSE - Novel nasal rinse compositions are disclosed. The nasal rinse comprises a dried particulate composed of honey and a carrier. The composition may be a co-processed composition wherein the honey and carrier are combined while the honey is in liquid form and processed together to produce the dried particulate. Methods for producing the nasal rinse compositions are also provided, as well as methods of use of the nasal rinse compositions for the prevention or treatment of nasal infection, rhinitis, or sinusitis. | 07-17-2014 |
20140199267 | METHODS FOR AMELIORATING SYMPTOMS OR CONDITIONS CAUSED BY STRESS - The invention provides methods for using fatty acid alkanolamides for ameliorating one or more symptoms or conditions caused by stress, e.g., loss of appetite, or for maintaining and enhancing nutrient and caloric intake by an animal under stress or that has experienced stress. Generally, the fatty acid alkanolamides in amounts of from about 0.1 to about 1500 mg/kg/day before, during or after stress, preferably on a regular or daily basis as a component of a food composition or as a dietary supplement. | 07-17-2014 |
20140205569 | METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING OSTEOARTHRITIS - The invention provides methods for preventing and treating osteoarthritis, preventing and treating the degradation of articular cartilage, and promoting and maintaining joint health in an animal. The methods comprise administering DGLA to the animals, preferably in amounts of from about 0.01 to about 100 mg/kg/day. | 07-24-2014 |
20140219962 | POROUS CHITOSAN SCAFFOLDS AND RELATED METHODS - Porous chitosan scaffold having high mechanical strength, methods for making the porous chitosan scaffold, and method for using the porous chitosan scaffold. | 08-07-2014 |
20140219963 | Extracellular Matrix-Derived Gels and Related Methods - Provided are methods for preparing gelled, solubilized extracellular matrix (ECM) compositions useful as cell growth scaffolds. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the gelled, solubilized ECM is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient. | 08-07-2014 |
20140271548 | DEVICE AND METHOD FOR PREPARING A FLUID COMPOSITION FOR COMPLETE OR SUPPLEMENTAL ENTERAL NUTRITION - The invention relates to a device for preparing a fluid composition for complete or supplemental enteral nutrition, comprising a liquid feeding device, an ingredient feeding device and a mixing device for mixing a liquid fed from the liquid feeding device and at least one ingredient fed from the ingredient feeding device, the mixing device comprising a mixer and a mixing container in which the liquid and the at least one ingredient are mixed by the mixer. The device is operable to move the mixing container relative to the mixer during mixing of the liquid and the at least one ingredient of the fluid composition to be prepared. Also provided is a method for preparing a fluid composition for complete or supplemental enteral nutrition using the device. | 09-18-2014 |
20140286904 | ANITMICROBIAL PEPTIDE PRODUCED BY INTESTINAL LACTOBACILLUS SALIVARIUS - An antimicrobial peptide having potent antibacterial activity against | 09-25-2014 |
20140294770 | COMPOSITIONS AND METHODS FOR SPINAL DISC REPAIR AND OTHER SURGICAL AND NON-SURGICAL INDICATIONS - The present invention features, inter alia, biocompatible compositions that include a poloxamer and one or more additives such as hyaluronic acid, gelatin, fibronectin, or a peptide fragment of fibronectin. The compositions are useful in tissue repair or remodeling, including repair of an injured spinal disc, in drug delivery, in cell culture, and in inhibiting the formation of adhesions. | 10-02-2014 |
20140301983 | HYALURONIC ACID-BINDING SYNTHETIC PEPTIDOGLYCANS, PREPARATION, AND METHODS OF USE - This invention pertains to the field of hyaluronic acid-binding synthetic peptidoglycans and methods of forming and using the same. | 10-09-2014 |
20140308245 | PEST CONTROL COMPOSITION AND METHOD FOR PREPARING SAME - Disclosed are a pest control composition which comprises extracts of used coffee grounds, yolk oil, and an EM activated solution as active ingredients, and a method for preparing a pest control composition which comprises (A) preparing an extract of coffee grounds by heating coffee grounds in boiling water for 5 minutes or more so that coffee oil is sufficiently extracted in the boiling water; (B) diluting the extract of coffee grounds with water; (C) preparing egg yolk oil by mixing egg yolk and edible oil; and (D) mixing an EM activated solution with the extract of coffee grounds of Operation (A) and the egg yolk oil of Operation (C). | 10-16-2014 |
20140322167 | PROCESS FOR BIOLOGICALLY COMBATING PSEUDOMONAS - The invention relates to a method for controlling the proliferation of | 10-30-2014 |
20140328800 | METHOD FOR THE BIOLOGICAL CONTROL OF LISTERIA - The invention relates to a method for controlling the proliferation of | 11-06-2014 |
20150010510 | Bone-Derived Extra Cellular Matrix Gel - Methods of manufacturing a bone-derived extracellular matrix (bECM) product are provided. Also provided are bECM products and methods of using those products. | 01-08-2015 |
20150023922 | METHODS FOR PROMOTING NEURONAL DEVELOPMENT AND/OR HEALTH - The present disclosure relates to methods for promoting neuronal health and/or development in a subject by providing nutritional compositions comprising a neurologic component, wherein the neurologic component may promote brain and nervous system development and further provide neurological protection and repair. The neurologic component may include lactoferrin, zine sulfate, one or more organosulfur compound, and mixtures thereof. | 01-22-2015 |
20150023923 | METHODS FOR PROMOTING NEURONAL DEVELOPMENT AND/OR HEALTH - The present disclosure relates to methods for promoting neuronal health and/or development in a subject by providing nutritional compositions comprising docosahexaenoic acid and alpha-lipoic acid. The nutritional composition may further include lactoferrin, a prebiotic, a probiotic, and mixtures thereof. Additionally the present disclosure provides methods for accelerating the development of neuronal activity and/or strengthening electrochemical synapse signaling by providing the nutritional composition(s) disclosed herein to a target subject. | 01-22-2015 |
20150118188 | DIRECT PHOTOPATTERNING OF ROBUST AND DIVERSE MATERIALS - The present invention relates to methods of metathesizing olefins using catalysts previously considered to be practically inactive. The present invention further relates to novel photosensitive compositions, their use as photoresists, and methods related to patterning polymer layers on substrates. Further, modifications to the compositions and method provide for an unprecedented functionalization of the compositions, useful for example in the preparation of sensors, drug delivery systems, and tissue scaffolds. The novel compositions and associated methods also provide for the opportunity to prepare 3-dimensional objects which provide new access to critically dimensioned devices, including for example photonic devices. | 04-30-2015 |
20150297644 | CO-PROCESSING METHODS FOR HONEY NASAL RINSE PRODUCTION - Nasal rinse compositions are disclosed. The nasal rinse comprises a dried particulate composed of honey and a carrier. The composition may be a co-processed composition wherein the honey and carrier are combined while the honey is in liquid form and processed together to produce the dried particulate. Methods for producing the nasal rinse compositions are also provided, as well as methods of use of the nasal rinse compositions for the prevention or treatment of nasal infection, rhinitis, or sinusitis. | 10-22-2015 |
20160015761 | USE OF PHOTOSYNTHETIC SCAFFOLDS IN TISSUE ENGINEERING - The present invention is concerned with a photosynthetic scaffold that delivers oxygen and its uses for tissue engineering and the treatment of ischemia. | 01-21-2016 |
20160050915 | COMPOSITIONS AND METHODS FOR ENHANCING MICROBIAL STABILITY - Described herein are compositions and methods for increasing the survivability of one or more beneficial microorganisms. | 02-25-2016 |
20160101062 | TREATMENT AND PREVENTION OF CARDIOVASCULAR DISEASE AND THROMBOSIS - Provided herein are compositions for the treatment and/or prevention of cardiovascular disease (CVD), and methods of application and use thereof. In particular, the present invention provides treatment and/or prevention of cardiovascular disease with compounds that inhibit the production of TMA in the gut, such as 3,3-dimethyl-1-butanol (DMB) or other compounds represented by Formula I or as shown in FIGS. | 04-14-2016 |
20160108097 | MONOMERIC GRIFFITHSIN TANDEMERS - The invention provides a construct containing two or more monomeric griffithsin molecules, optionally joined by a linker, as well as conjugate comprising the construct, a nucleic acid encoding the construct or conjugate, vectors, and cells. A nucleic acid encoding the polypeptide or fusion protein, as well as compositions or cells comprising the polypeptide, fusion protein, or nucleic acid also are provided. | 04-21-2016 |
20160120912 | COMPOSITIONS AND METHOD FOR PROMOTING NERVE GROWTH AND REGENERATION - The invention relates generally to the fields of biology and health sciences. More particularly, the invention relates to compositions and methods for modulating cellular physiology and pathological processing using a combination of compounds that can be found in amniotic membrane tissue and umbilical cord tissue preparations. | 05-05-2016 |
20160249624 | METHOD FOR BIOLOGICALLY COMBATING NAEGLERIA FOWLERI, AND DISINFECTING AGENT CONTAINING PROTOZOA OF THE SPECIES WILLAERTIA MAGNA | 09-01-2016 |