Entries |
Document | Title | Date |
20080260784 | Compositions and Methods for Modulating an Immune Response - The present invention provides a composition for suppressing an inflammatory immune response comprising the excretory/secretory (ES) component of | 10-23-2008 |
20090074818 | Composition Comprising Parasite Eggs And Methods For Isolation And Storage Of Parasite Eggs - The invention relates to a composition for storage and development of eggs from helminthic parasites, where the composition further comprises a liquid carrier having a pH value of below 7 at a temperature of from 1° C. to ambient temperature. The liquid carrier can be sulphuric acid, H | 03-19-2009 |
20090130149 | BIOACTIVE COPEPOD-COMPOSITIONS, PROCESSES FOR THE PRODUCTION THEREOF, AND USE THEREOF TO PREVENT OR TREAT HOSTS INFESTED BY PHYLOGENETICALLY SIMILAR ECTOPARASITES - The present invention relates to novel compositions comprising copepods, such as marine | 05-21-2009 |
20100003285 | Human Hookworm Vaccine - A vaccine for human hookworm is provided. The vaccine comprises at least one L3 larval stage antigen (e.g. Na-ASP-2 or Na-SAA-2) and at least one adult stage human hookworm antigen (e.g. Na-APR-1, Na-CP-2, Na-CP-3, Na-CP-4, Na-CP-5, or Na-GST-1) and adjuvants. | 01-07-2010 |
20100074924 | MEMBRANE PROTEIN SM29 OF SCHISTOSOMA MANSONI AND USES THEREOF FOR TREATING AND DIAGNOSING SCHISTOSOMIASIS - The present invention relates to a Sm29 membrane protein and to an immunoenzymatic assay (diagnosis) capable of detecting specific IgG antibodies against the Sm29 protein present in the serum of schistosomiasis patients, the use of Sm29 as a vaccine in the prevention of schistosomiasis and the use of Sm29 in the treatment of allergic diseases. The immunoenzymatic assay is capable of detecting specific IgG antibodies against Sm29 present in the sera of individuals with schistosomiasis. Support-adsorbed Sm29 is reacted with the test sera. After incubation with the conjugate, the reaction is developed with a solution composed of the enzyme substrate used in the conjugate (chro-mogen). After the development of the reaction, it is paralyzed with the acid solution and read in a spectrophotometer. The vaccine using Sm29 is capable of reducing the number of adult worms in vaccinated animals in 31.2% (without adjuvant); 51% and 56.7% (with adjuvant). Vaccination is also capable of reducing the number of parasite eggs in the intestine in 37.6% and 60%, and the number of granulomas in the liver of the host in 48% and 61%. Vaccination is done by using 10-50 μg of recombinant Sm29 with or without the use of a sub-cutaneously-applied adjuvant. After 15 days, two booster doses are applied with a 15-day interval containing 10-50 μg of recombinant Sm29 with or without the use of an adjuvant. The stimulation of mononuclear cells of the peripheral blood of asthmatic patients shows that Sm29 is capable of inducing a high production of IL-10 the innate immune system cells, thus evidencing its potential use as a therapeutic in the treatment of allergic diseases. | 03-25-2010 |
20100255037 | NOVEL SEQUENCES OF HAEMONCHUS CONTORTUS, IMMUNOGENIC COMPOSITIONS, METHODS FOR PREPARATION AND USE THEREOF - The present invention relates to novel sequences of | 10-07-2010 |
20100303865 | USE OF OXAZOLE DERIVATIVES FOR CONTROLLING FISH PARASITES - The present invention relates to the use of compounds of formula (I), wherein R | 12-02-2010 |
20110008390 | Production of a Viable, Storable Worm Egg Suspension - The present application describes a novel, advantageous purification method which guarantees the embryonation capability and the viability of a worm egg suspension. The | 01-13-2011 |
20110091507 | SCHISTOSOMIASIS VACCINE COMPOSITIONS AND METHODS OF USE - No effective vaccine exists for the devastating parasitic disease of Schistosomiasis. The present invention focuses on Sm-p80, a functionally important antigen of | 04-21-2011 |
20110165197 | ADJUVANT COMPOSITIONS AND METHODS FOR ENHANCING IMMUNE RESPONSES TO POLYNUCLEOTIDE-BASED VACCINES - The invention provides adjuvants, immunogenic compositions, and methods useful for polynucleotide-based vaccination and immune response. In particular, the invention provides an adjuvant of cytofectin:co-lipid mixture wherein cytofectin is GAP-DMORIE. | 07-07-2011 |
20110171265 | Composition Comprising Parasite Eggs and Methods for Isolation and Storage of Parasite Eggs - The invention relates to a composition for storage and development of eggs from helminthes parasites, where the composition further comprises a liquid carrier having a pH value of below 7 at a temperature from 10 C to ambient temperature. The liquid carrier can be sulphuric acid, H | 07-14-2011 |
20110200640 | MULTIVALENT ANTIHELMINTHIC VACCINE - A multivalent anthelmintic vaccine targets both hookworm and schistosomiasis. The vaccine includes, at a minimum, a recombinant third-stage larval hookworm antigen, a recombinant adult stage hookworm antigen, and a recombinant schistosome antigen. Preferably, the hookworm antigens are | 08-18-2011 |
20110212134 | ANTI-ARTHROPOD VECTOR VACCINES, METHODS OF SELECTING AND USES THEREOF - The present invention provides methods of selecting and uses of anti-arthropod vector vaccines to prevent | 09-01-2011 |
20120128721 | SCHISTOSOMA VACCINE - The method for large scale production of a full length Schistosomal paramyosin coiled coil dimer composition is carried out by providing a composition comprising recombinant paramyosin, contacting the composition with a strand separation agent to remove paramyosin fragments and other contaminants. The purified paramyosin is used in vaccines for humans and bovine animals to induce immunity against schistosomal infection. | 05-24-2012 |
20130064853 | PARASITE VACCINE - The present invention provides one or more antigens from the fourth stage (L4) larvae of non-blood feeding parasitic nematodes, for raising an immune responses in an animals, in particular bovines. The invention further provides methods of making immunogenic and/or vaccine compositions. | 03-14-2013 |
20130084308 | ANTI-ARTHROPOD VECTOR VACCINES, METHODS OF SELECTING AND USES THEREOF - The present disclosure provides methods of selecting and uses of anti-arthropod vector vaccines to prevent Leishmaniasis. The present disclosure also provides compositions for vaccines to prevent Leishmaniasis. | 04-04-2013 |
20130273111 | DIAGNOSTIC ASSAYS AND METHODS OF USE FOR DETECTION OF FILARIAL INFECTION - The polynucleotide encoding the antigen Wb123 from the filarial nematode | 10-17-2013 |
20150079134 | TREATMENT TO PROMOTE WOUND HEALING - The invention relates to a field of tissue repair and regeneration. More particularly, the invention relates to a composition for promoting cutaneous wound healing. In one embodiment, the composition is composed of one or more metazoan parasites or a mimic thereof sufficient to promote helminth-induced type-2 immune response. Preferably, the composition contains | 03-19-2015 |
20150329603 | Compositions and Methods Related to Parasites - In some aspects, the invention relates to compositions and methods for preventing or treating a hookworm infection. In some aspects, the invention relates to nucleic acids, peptides, proteins, antigens, and cells that encode, comprise, and/or express one or more hookworm amino acid sequences, e.g., for use in manufacturing a vaccine. | 11-19-2015 |
20160045581 | Parasitic Biological Agents for Treatment and Prevention of Graft Versus Host Disease - The invention relates to helminthic parasite preparations and their use for treatment or prevention of GVHD in a subject that has undergone a transplant. The invention also related to helminthic parasite preparations and their use for prevention of GVHD in a subject prior to a transplant. | 02-18-2016 |