Entries |
Document | Title | Date |
20080274132 | VACCINES FOR BLOCKING TRANSMISSION OF PLASMODIUM VIVAX - The present invention relates novel methods and compositions for blocking transmission of | 11-06-2008 |
20080279881 | Truncated recombinant major outer membrane protein antigen (R56) of orientia tsutsugamushi strains karp, kato and gilliam and its use in antibody based detection assays and vaccines - A recombinant, refolded non-fusion polypeptide expressed from a truncated r56 gene of the causative agent of scrub typhus, | 11-13-2008 |
20080299143 | Cryptosporidium parvum antigens, antibodies thereof and diagnostic and therapeutic compositions thereof - Cloning and expression of genes encoding | 12-04-2008 |
20090017055 | PLASMODIUM LIVER STAGE ANTIGENS - The invention provides isolated liver stage Plasmodium polypeptides comprising an amino acid sequence selected from the group consisting of SEQ ID NOs: 1-48 and immunogenic derivatives thereof. The invention also provides isolated nucleic acid molecules encoding the liver stage Plasmodium polypeptides of the invention, compositions comprising one or more liver stage Plasmodium polypeptides of the invention, methods for inducing an immune response against the liver stage Plasmodium polypeptides, and methods for treating and diagnosing liver stage malaria. | 01-15-2009 |
20090028892 | Ostertagia Vaccine - The present invention relates to nucleic acid sequences encoding | 01-29-2009 |
20090060935 | AMEBIASIS VACCINE - An isolated protein fragment containing an epitope which is specific for | 03-05-2009 |
20090092630 | Chimeric recombinant antigens of toxoplasma gondii - A method for treatment or prevention of | 04-09-2009 |
20090104219 | Antigenic polypeptide SE36 of malaria plasmodium, process for purification thereof, and vaccine and diagnostic agent using the antigen - The present invention provides a polypeptide SE36 derived from the N-terminal domain (47 kd) of SERA (serine-repeat antigen) produced by malaria parasite, | 04-23-2009 |
20090162393 | Vaccine composition and uses thereof - The present invention provides a vaccine composition including a nucleic acid that encodes an amoeba-derived antigen (or a peptide molecule encoded thereby), or fragments or variants thereof. The present invention also provides for the use of such vaccine compositions in eliciting an immune response and/or protective immunity in a host against amoebic infection and screening a sample for the presence of amoebae. | 06-25-2009 |
20090175895 | METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING MALARIA - The present invention provides compositions and methods useful in the treatment or prevention of a condition caused by or associated with infection by | 07-09-2009 |
20090191236 | PIROPLASMID VACCINE - The invention relates to a Piroplasmid protein or an immunogenic fragment of said protein, and to a nucleic acid encoding said Piroplasmid protein or said immunogenic fragment. Furthermore, the invention relates to cDNA fragments, recombinant DNA molecules and live recombinant carriers comprising said nucleic acid. Also the invention relates to host cells comprising said cDNA fragments, recombinant DNA molecules and live recombinant carriers. Finally, the invention relates to vaccines comprising a Piroplasmid protein or an immunogenic fragment of said protein, to methods for the preparation of such vaccines, to the use of such proteins or fragments for vaccine purposes, and to diagnostic tests. | 07-30-2009 |
20090196883 | Plasmodium vivax hybrid circumsporozoite protein and vaccine - Described in this application is a synthetic | 08-06-2009 |
20090196884 | Malaria Vaccines - The present invention relates to a synthetic antigenic sequence which represents a combination of epitope-containing sequences from the highly polymorphic block 2 repeat region of K1-type | 08-06-2009 |
20090202579 | METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING MALARIA (2) - The present invention provides compositions and methods useful in the treatment or prevention of a condition caused by or associated with infection by | 08-13-2009 |
20090297550 | Chloroplast-derived human vaccine antigens against malaria - Disclosed is a method of making a malaria vaccine, the method comprising stably transforming a plant by inserting into its plastid genome a nucleic acid sequence encoding and operable to constitutively express a malaria antigenic polypeptide selected from AMA-1, MSP-1 or both; harvesting the stably transformed plant in whole or in part; purifying the expressed malaria antigenic polypeptide from the harvested plant; and packaging the purified antigenic polypeptide under sterile conditions in an amount for a predetermined dosage. Also disclosed is an oral vaccine effective in raising malaria antibodies in a susceptible host, the vaccine comprising leaf material from an edible plant containing plastids stably transformed to constitutively express a fusion polypeptide consisting essentially of cholera toxin B subunit and a malaria antigenic polypeptide selected from AMA-1, MSP-1 or both. | 12-03-2009 |
20090304732 | Cryptosporidium Hominis Genes and Gene Products for Chemotherapeutic, Immunoprophylactic and Diagnostic Applications - genes and gene products are provided. The genes and gene products are useful for chemotherapeutic, immunotherapeutic, immunoprophylactic and diagnostic applications. | 12-10-2009 |
20090324634 | Trypanosoma Antigens, Vaccine Compositions, and Related Methods - The present invention relates to the intersection of the fields of immunology and protein engineering, and particularly to antigens and vaccines useful in prevention of infection by | 12-31-2009 |
20100098717 | Polypeptides Recognized by Anti-Trichinella Antibodies, and Uses Thereof - The present invention relates to new polypeptides recognized by anti- | 04-22-2010 |
20100119539 | VACCINE AGAINST MALARIA, BASED ON THE 200L SUBUNITI OF PLASMODIUM VIVAX MSP1 PROTEIN - A candidate subunit for a vaccine against malaria caused by | 05-13-2010 |
20100150951 | PLASMODIUM FALCIPARUM ANTIGENS INDUCING PROTECTIVE ANTIBODIES - The present invention provides a vaccine against malaria containing a polypeptide having an epitope contained within a merozoite surface protein and a method for immunizing against malaria by administering the vaccine. | 06-17-2010 |
20100166794 | PLASMODIUM LIVER STAGE ANTIGENS - The invention provides isolated liver stage | 07-01-2010 |
20100172928 | Recombinant viral-based malaria vaccines - The present invention relates to novel vaccines against malaria infections, based on recombinant viral vectors, such as alpha viruses, adenoviruses or vaccinia viruses. The recombinant viral-based vaccines can be used to immunize against different | 07-08-2010 |
20100172929 | Malaria Vaccines - The invention provides isolated placental | 07-08-2010 |
20100209446 | Ostertagia Vaccine - The present invention relates to nucleic acid sequences encoding a 30 kD | 08-19-2010 |
20100215685 | ACYL PSEUDODIPEPTIDES WHICH CARRY A FUNCTIONALIZED AUXILIARY ARM - The present invention is directed in particular to dipeptide-like compounds derived from functionally substituted amino acids, having fatty acid chains bound thereto through amidification of the amine functional groups of said dipeptide-like compounds, one end portion of which bears an accessory functional side chain spacer, with the other end portion being an acid group either in neutral or charged state. | 08-26-2010 |
20100285049 | Ex vivo animal or challenge model as method to measure protective immunity directed against parasites and vaccines shown to be protective in the method - The invention relates to an ex vivo animal or challenge model as a method to identify protective (recombinant) proteins and rapidly measure protective immunity in intestinal segments directed against parasites and vaccines directed against parasitic infections. The invention further relates to vaccines directed against infection with parasites, such as | 11-11-2010 |
20100291133 | RECOMBINANT PROTEIN CONTAINING A C-TERMINAL FRAGMENT OF PLASMODIUM MSP-1 - The invention relates to a recombinant protein fabricated in a baculovirus system, of which the essential constitutive polypeptide sequence is that of a C-terminal fragment of 19 kilodalton (p19) of the surface protein 1 (protein MSP-1) of the merozoite parasite of the | 11-18-2010 |
20100297163 | RECOMBINANT MALARIA VACCINE - The present invention refers to a recombinant malaria vaccine and a method for its manufacture. | 11-25-2010 |
20110008381 | SUPPRESSION OF ALLERGIC INFLAMMATION BY ASCARIS HEME-BINDING PROTEIN (HBP) - This invention relates, e.g., to a method for suppressing inflammation (e.g. allergic inflammation, for example asthma caused by ragweed), a Th1-mediated condition and/or a Th2-mediated condition and/or a condition in which administration of an antioxidant would be beneficial, in a subject in need thereof, comprising administering to the subject an anitinflammatory-effective amount of | 01-13-2011 |
20110020387 | MALARIA VACCINE - A fusion protein, from | 01-27-2011 |
20110038887 | Novel Vaccine Against Trypanosoma Cruzi Infection - The present invention relates to a vaccine against | 02-17-2011 |
20110104195 | Plasmodium falciparum sporozoite and liver stage antigens - The invention provides novel malaria polypeptides expressed at the pre-erythrocytic stage of the malaria life-cycle. The antigens can be utilized to induce an immune response against malaria in a mammal by administering the antigens in vaccine formulations or expressing the antigens in DNA or other nucleic acid expression systems delivered as a vaccine formulation. | 05-05-2011 |
20110117120 | Plasmodium falciparum HLA class I restricted T-cell epitopes - The invention relates immunogenic polypeptides and epitopes from | 05-19-2011 |
20110189218 | Plasmodium vivax hybrid circumsporozoite protein and vaccine - Described in this application is a synthetic | 08-04-2011 |
20110206714 | MALARIA VACCINE COMPOSITIONS AND CONSTITUENTS WHICH ELICIT CELL MEDIATED IMMUNITY - Malaria vaccines based on polyepitope constructs that elicit cell-mediated immunity against a broad spectrum of malaria parasites and which cover the majority of HLA alleles are provided. Epitopes in the polyepitope constructs are from regions of the | 08-25-2011 |
20110280901 | Diagnosis and treatment of Trypanosoma cruzi infection and chagas disease - Provided herein are vaccine compositions for control of | 11-17-2011 |
20110311571 | METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING MALARIA USING AN INVASION LIGAND DIRECTED TO A PROTEASE-RESISTANT RECEPTOR - This invention relates to an immunogenic molecule comprising a contiguous amino acid sequence of an invasion ligand of a strain of | 12-22-2011 |
20110311572 | NUCLEOTIDE AND AMINO ACID SEQUENCES ENCODING AN EXPORTED PROTEIN 1 DERIVED FROM PLASMODIUM VIVAX AND USES THEREOF - The present invention is directed to novel polynucleotides and polypeptides directed to EXP1 of | 12-22-2011 |
20120003259 | MOLECULE - We describe an Fve polypeptide being a fragment, homologue, variant or derivative of Fve protein, which comprises at least one biological activity of Fve protein. uses of such a polypeptide, etc, and nucleic acids encoding these, in the treatment and prevention of allergy and cancer are also disclosed. | 01-05-2012 |
20120058138 | Novel Adenovirus Vectors - An adenoviral vector comprising a promoter further comprising a fragment of the 5′ untranslated region of the CMV IE1 gene including intron A and a nucleic acid sequence encoding a pathogen or tumour antigen for use as a medicament. | 03-08-2012 |
20120076815 | IDENTIFICATION AND CHARACTERIZATION OF RACEMASES, DEFINITION OF PROTEIN SIGNATURES, AND A TEST FOR DETECTING D-AMINO ACID AND FOR SCREENING MOLECULES CAPABLE OF INHIBITING THE ACTIVITY OF RACEMASE, ESPECIALLY PROLINE RACEMASE - This invention provides identification and characterization of racemases and definition of protein signatures of these racemases. This invention also provides identification of nucleic acid molecules encoding a peptide consisting of a motif characteristic of the protein signatures, and to the peptides consisting of these motifs. Antibodies specific for the peptides and to immune complexes of these antibodies with the peptides are also provided. Further, the invention relates to methods and kits for detecting racemases using the nucleic acid molecules of the invention, as well as the peptides consisting of the motifs and antibodies to these peptides. | 03-29-2012 |
20120076816 | NOVEL MALARIA VACCINE - The present invention provides a vaccine for preventing and/or treating | 03-29-2012 |
20120082694 | Recombinant Viral-Based Malaria Vaccines - Described are vaccines against malarial infections, which are based on recombinant viral vectors, such as alpha viruses, adenoviruses, or vaccinia viruses. The recombinant viral-based vaccines can be used to immunize against different | 04-05-2012 |
20120107342 | Ex vivo animal or challenge model as method to measure protective immunity directed against parasites and vaccines shown to be protective in the method - Described is an ex vivo animal or challenge model used as a method to identify protective (e.g., recombinant) proteins and rapidly measure protective immunity in intestinal segments directed against parasites and vaccines directed against parasitic infections. Further described are vaccines directed against infection with parasites, such as | 05-03-2012 |
20120164167 | SUB-REGION OF A PLASMODIUM PROTEIN WITH IMPROVED VACCINE POTENTIAL, AND MEDICAL USES THEREOF - The present application relates to a sub-region of a | 06-28-2012 |
20120231029 | ENHANCED MALARIA MSP-1 SUBUNIT VACCINE - Recombinant subunit proteins derived from the MSP-1 C-terminal region of the parasite | 09-13-2012 |
20120237538 | RECOMBINANTLY EXPRESSED PLASMODIUM CelTOS ANTIGEN AND METHODS OF USE THEREOF - A synthetic nucleotide, which transcribes as the cell-traversal protein for ookinetes and sporozoites (CelTOS) antigen of Malaria | 09-20-2012 |
20120244178 | Plasmodium falciparum antigens - The invention relates to antigens, associated with sterile immunity, and methods of their use, in an immunogenic formulation to confer an immune response against | 09-27-2012 |
20120263746 | USE OF AN L3 AND/OR L5 SOURCE AS A VACCINE OR AS A DIAGNOSTIC FOR A PARASITIC DISEASE - The invention relates to composition comprising an L3 and/or an L5 source and optionally an adjuvant for the preparation of a medicine for the treatment or prevention of a parasitic disease and to its diagnostic use of said parasitic disease. | 10-18-2012 |
20120276131 | ANTI-TRYPANOSOMIASIS VACCINES AND DIAGNOSTICS - The present invention has as an object a novel genetic material coding for trans-sialidase-like proteins of African trypanosomes, and relates to the use of said genes and proteins in vaccines, therapeutics and diagnostics. The present invention also relates to the immunization of human and/or nonhuman animals against trypanosomosis. | 11-01-2012 |
20120301497 | Plasmodium vivax Hybrid Circumsporozoite Protein and Vaccine - Described in this application is a synthetic | 11-29-2012 |
20120308598 | MALARIA VACCINES BASED ON APICOMPLEXAN FERLINS, FERLIN-LIKE PROTEINS AND OTHER C2-DOMAIN CONTAINING PROTEINS - The present invention relates to peptides comprising at least one antigenic determinant or epitope of an apicomplexan Ferlin, Ferlin-like protein and/or another C2-domain containing protein for use as malaria vaccines. It further relates to compositions comprising said peptides and to the use of such compositions as malaria vaccines. | 12-06-2012 |
20120308599 | VACCINE AND METHODS OF USE AGAINST STRONGYLOIDES STERCORALIS INFECTION - The polynucleotide encoding the SSIR gene from the nematode | 12-06-2012 |
20120328645 | Malaria Vaccines - Transcript profiles for irradiated and non-irradiated | 12-27-2012 |
20130045225 | Synthetic Antigen Based on the Ligand Domain of the Plasmodium vivax Duffy Binding Protein - The disclosure provides compositions that are useful for eliciting a strain-transcending immune response in an animal or human directed against the blood-stage of the malarial parasite | 02-21-2013 |
20130108660 | ANTI-TRYPANOSOME THERAPEUTIC AND DIAGNOSTIC APPLICATIONS | 05-02-2013 |
20130129766 | RECOMBINANT PLASMODIUM FALCIPARUM MEROZOITE SURFACE PROTEINS 4 AND 5 AND THEIR USE - Accordingly, the invention provides constructs in which the nucleic acids encoding | 05-23-2013 |
20130129767 | VACCINES AGAINST PREGNANCY-ASSOCIATED MALARIA - The present invention relates to specific regions of the N-terminal portion of the VAR2CSA protein and to the use of such specific regions in the prevention of pregnancy-associated malaria. The invention also provides immunogenic compositions and vaccines that are useful for preventing malaria in pregnant women. | 05-23-2013 |
20130156806 | Antigenic Polypeptides of Trichinella and Uses Thereof - The invention relates to novel polypeptides which are recognized by anti- | 06-20-2013 |
20130177584 | Recombinant Polyprotein Vaccines For the Treatment and Diagnosis of Leishmaniasis - Compositions and methods for preventing, treating and detecting leishmaniasis are disclosed. The compositions generally comprise fusion polypeptides comprising multiple | 07-11-2013 |
20130183332 | Treatment and Prevention of Malaria - There are provided antigens, vectors encoding the antigens, and antibodies and other binding compounds to the antigens and uses thereof in the prevention or treatment of malaria. In particular, compositions are provided comprising a Reticulocyte-binding protein Homologue 5 (PfRH5) antigen having at least 90% identity with SEQ ID NO: 1, or a fragment thereof; or which comprise a viral vector that expresses PfRH5 antigen having at least 90% identity with SEQ ID NO: 2, or a fragment thereof. | 07-18-2013 |
20130216569 | VACCINE - The present invention provides a polypeptide comprising the amino acid sequence as shown as SEQ ID No. 1 or a homologue or fragment thereof, a nucleic acid capable of encoding such a polypeptide and a vaccine comprising such a polypeptide/nucleic acid. The vaccine may be used for the treatment and/or prevention of a disease associated with an apicomplexan parasite. | 08-22-2013 |
20130230551 | Allergy Inhibitor Compositions And Kits And Methods Of Using The Same - Compositions, methods, and kits for inhibiting an allergic response against an allergenic protein are disclosed. Compositions, methods and kits for inhibiting an allergic response against an a flea allergenic protein; a feline allergenic protein; a canine allergenic protein; a dust mite allergenic protein; a peanut allergenic protein; a Japanese cedar allergenic protein; and a | 09-05-2013 |
20130236490 | Multivalent Vaccine for Filariasis - The present invention is a multivalent vaccine for immunizing an animal against filariasis. In some embodiments, the antigens of the multivalent vaccine are protein-based, DNA-based, or a combination thereof. | 09-12-2013 |
20130251740 | IMMUNOGENIC AGENTS - The present invention relates to immunogenic agents based on trypanosomes, related compositions, and related methods. | 09-26-2013 |
20130259890 | PLASMODIUM FALCIPARUM CIRCUMSPOROZOITE VACCINE GENE OPTIMIZATION FOR SOLUBLE PROTEIN EXPRESSION - The present invention provides novel nucleotide sequence and other constructs used for expression of novel recombinant | 10-03-2013 |
20130273094 | VACCINES AGAINST TOXOPLASMA GONDII - Vaccines are disclosed against parasites. The vaccines include peptides in an immunological composition. In particular, the parasite is | 10-17-2013 |
20130273095 | VACCINE COMPOSITION FOR CONTROLLING ECTOPARASITE INFESTATIONS - The present invention relates to the use of a peptide of P0 ribosomal protein in the manufacture of a vaccine composition to control of ectoparasite infestations and therefore the transmission of their associated pathogens. This peptide is located between 267 and 301 amino acids of the P0 protein, and can be obtained by recombinant means or by chemical synthesis. This peptide can be fused to a carrier protein or peptide, or an immuno-carrier and be included in an oily formulation. The formulations comprising the peptide vaccine confer protection against ticks and ectoparasites known as “sea lice” without generating autoimmunity in the host organism. Among these ticks may be mentioned species as | 10-17-2013 |
20130280290 | Nucleic Acid and Amino Acid Sequences, and Vaccine for the Control of Ectoparasite Infestations in Fish - The present invention is related with the isolation and cloning of a new gene, the production of the protein encoded by this gene by using recombinant systems, and the use of this antigen in a vaccine formulation as a purified protein and/or naked DNA, to induce an immune response in aquatic organisms against different ectoparasite species, including the known as sea lice, and pathogens associated with these infestations. The vaccine preparations, administered by oral route, immersion bath or injection, demonstrated its efficacy by producing IgM humoral immune response and reducing the number of parasites per fish in the vaccinated fishes. | 10-24-2013 |
20130315947 | Vaccination of Animals to Elicit a Protective Immune Response Against Tick Infestations and Tick-Borne Pathogen Transmission - Two antigenic and immunogenic proteins of the cattle tick, | 11-28-2013 |
20130323275 | METHODS AND COMPOSITIONS FOR INDUCING A T-CELL RESPONSE TO PLASMODIUM SPECIES - The present invention relates to methods of inducing a T-cell response against a | 12-05-2013 |
20130323276 | MALARIA VACCINES BASED ON PRE-ERYTHROCYTIC ANTIGENS FROM P. FALCIPARUM - The present invention relates to polypeptides or fragments thereof for use as malaria vaccines. It also relates to nucleic acid molecules coding for the polypeptides of the invention. It further relates to compositions comprising such polypeptides or fragments thereof or the nucleic acid molecules, in particular combinations of such polypeptides or fragments thereof, and the use of such compositions as malaria vaccines. | 12-05-2013 |
20140004141 | Methods And Compositions Of Protein Antigens For The Diagnosis And Treatment Of Toxoplasma Gondii Infections And Toxoplasmosis | 01-02-2014 |
20140093530 | MALARIA VACCINES - The present invention relates to a synthetic antigenic sequence which represents a combination of epitope-containing sequences from the highly polymorphic block 2 repeat region of K1-type | 04-03-2014 |
20140093531 | LUTZOMYIA LONGIPALPIS POLYPEPTIDES AND METHODS OF USE - Substantially purified salivary | 04-03-2014 |
20140170182 | PRODUCTION OF A CYSTEINE RICH PROTEIN - The present invention relates to a method for the production of correctly folded Pfs48/45. This is achieved in the | 06-19-2014 |
20140193452 | NOVEL AGENTS FOR THE PREVENTION OF LEISHMANIASIS - The invention relates to nucleic acid constructions, characterized in that they comprise nucleic acids which are isolated in the sense position and which are capable of coding for an immunogenic protein of promastigotes or amastigotes of | 07-10-2014 |
20140212452 | Vaccination of Animals to Elicit A Protective Immune Response Against Tick Infestations and Tick-Borne Pathogen Transmission - Two antigenic and immunogenic proteins of the cattle tick, | 07-31-2014 |
20140271702 | Vaccination of Companion Animals to Elicit a Protective Immune Response Against Tick Infestations and Tick-Borne Pathogen Transmission - Compositions of either the aquaporin protein from the cattle tick, | 09-18-2014 |
20140322257 | FUSION PROTEINS REPRESENTING DIFFERENT NS: PROPOSAL FOR A VACCINE AGAINST ALLERGY TO MITES - The present invention refers to recombinant DNA molecules codifying fused peptides from different allergens from | 10-30-2014 |
20140348870 | IMMUNOGENIC PLASMODIUM FALCIPARUM ANTIGEN COMPOSITIONS AND USES THEREOF - Contemplated compositions and methods employ selected antigens form | 11-27-2014 |
20140356391 | AMINO ACID SEQUENCES FOR CLINICAL REMISSION OF PSORIASIS AND RELATED DISEASES. - Polypeptides comprising amino acid sequences of particulate antigens isolated from various species of | 12-04-2014 |
20150017200 | FUSION PROTEINS AND THEIR USE IN THE DIAGNOSIS AND TREATMENT OF LEISHMANIASIS - The present invention relates generally to a fusion protein made from a synthetic gene construct comprising of elements derived from the | 01-15-2015 |
20150037365 | NOVEL MALARIA VACCINE - The present invention provides a vaccine for preventing and/or treating | 02-05-2015 |
20150037366 | METHOD FOR TREATING INFLAMMATION - A method for reducing or alleviating inflammation in a subject includes administering to the subject a therapeutically effective amount of: (a) Ac-TMP-1 or a biologically active fragment or variant of Ac-TMP-1; (b) Ac-TMP-2 or a biologically active fragment or variant of Ac-TMP-2; or (c) a combination of (a) and (b), to thereby reduce or alleviate inflammation in the subject. A method for preventing or treating asthma or inflammatory bowel disease in a subject includes administering to the subject a therapeutically effective amount of: (a) Ac-TMP-1 or a biologically active fragment or variant of Ac-TMP-1; (b) Ac-TMP-2 or a biologically active fragment or variant of Ac-TMP-2; or (c) a combination of (a) and (b), to thereby prevent or treat asthma or inflammatory bowel disease in the subject. The subject may be a mammal, inclusive of humans. | 02-05-2015 |
20150056243 | MULTICOMPONENT OR MONOCOMPONENT VACCINE TO BE USED AGAINST CHAGAS DISEASE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, PROCEDURE FOR THE OBTENTION OF IMMUNOGEN OF SAID VACCINES, AND NUCLEIC ACID USED IN SAID PROCEDURE - A vaccine against the Chagas disease, capable of stimulating the immune response against the trans-sialidase virulence factor of the | 02-26-2015 |
20150079126 | Plasmodium falciparum antigens - The invention relates to antigens, associated with sterile immunity, and methods of their use, in an immunogenic formulation to confer an immune response against | 03-19-2015 |
20150079127 | CANINE BABESIOSIS VACCINE ANTIGEN - The present invention relates to the field of veterinary parasitology, especially of canine Babesiosis. In particular the invention relates to a polypeptide being a novel canine | 03-19-2015 |
20150086583 | MUCIN-ASSOCIATED SURFACE PROTEIN AS VACCINE AGAINST CHAGAS DISEASE - Use of synthetic peptides derived from | 03-26-2015 |
20150093408 | Lyme disease vaccine, genetic construct, recombinant protein, method for designing genetic construct, method for producing vaccine, method for producing recombinant proteins, use of recombinant proteins in the production of Lyme disease vaccine - The present invention relates to a Lyme disease vaccine, a genetic construct, recombinant protein, method for genetic construct design, method for vaccine delivery, method for recombinant proteins delivery, use of recombinant proteins in the production of Lyme disease vaccine. In particular, the method concerns the use of TROSPA and TROSPA-Salp15 recombinant proteins derived from castor bean tick ( | 04-02-2015 |
20150125482 | Recombinant polypeptide construct comprising Plasmodium falciparum circumsporozoite protein HLA class I restricted T-cell epitopes - The invention relates to a recombinant polypeptide construct comprising epitopes from | 05-07-2015 |
20150125483 | FUSION PROTEINS OF CILIATE GRANULE LATTICE PROTEINS, GRANULAR PROTEIN PARTICLES THEREOF, AND USES THEREFOR - This invention is directed to methods for the production of immunogenic granular particles. In certain embodiments, the invention is directed to methods and products for the production immunogenic granular particles produced in ciliates. In certain embodiments, the invention is directed to compositions comprising Grl/Ag fusion polypeptides. | 05-07-2015 |
20150147349 | Conformation-Stabilized TRAP Antigens - This invention relates to compositions and methods for eliciting an immune response against a parasite of the genus | 05-28-2015 |
20150297699 | MALARIA ANTIGENS AND METHODS OF USE - The invention is directed to a composition comprising one or more polypeptides or one or more nucleic acid sequences that can induce a protective immune response against | 10-22-2015 |
20150297700 | Novel Adenovirus Vectors - An adenoviral vector comprising a promoter further comprising a fragment of the 5′ untranslated region of the CMV IE1 gene including intron A and a nucleic acid sequence encoding a pathogen or tumour antigen for use as a medicament. | 10-22-2015 |
20150307566 | VACCINE AND METHODS FOR DETECTING AND PREVENTING FILARIASIS - The present invention is a multivalent vaccine for immunizing an animal against filariasis. In some embodiments, the antigens of the multivalent vaccine are protein-based, DNA-based, or a combination thereof. This invention also provides a method and kit for detecting a filarial nematode and determining vaccine efficacy. | 10-29-2015 |
20150313980 | Genetic Attenuation of Plasmodium by B9 Gene Disruption - Disclosed herein are mutant | 11-05-2015 |
20150366958 | TREATMENT AND PREVENTION OF MALARIA - The present invention relates to recombinant fragments of | 12-24-2015 |
20160000895 | COMPOSITIONS AND METHODS OF ENHANCING IMMUNE RESPONSES TO EIMERIA OR LIMITING EIMERIA INFECTION - Vaccine vectors and methods of using the vaccine vectors to enhance the immune response to an Apicomplexan parasite and reduce the morbidity or morality associated with subsequent infection are provided herein. The vaccine vectors include a polynucleotide encoding a Rhomboid polypeptide and optionally include an immune-stimulatory polypeptide suitably expressed on the surface of the vaccine vector. | 01-07-2016 |
20160031953 | Recombinantly Expressed Plasmodium CelTOS Antigen and Methods of Use Thereof - A synthetic nucleotide, which transcribes as the cell-traversal protein for ookinetes and sporozoites (CelTOS) antigen of Malaria | 02-04-2016 |
20160038580 | SOLUBLE RECOMBINANT PLASMODIUM FALCIPARUM CIRCUMSPOROZOITE PROTEIN, USE IN VACCINES, METHODS OF MAKING AND USES THEREOF - The present invention provides novel nucleotide sequence and other constructs used for expression of novel recombinant | 02-11-2016 |
20160051649 | Vaccine Against Rhipicephalus Ticks - The present invention generally relates to the fields of parasitology and immunology, and especially to a vaccine against | 02-25-2016 |
20160083438 | Plasmodium falciparum antigens - The invention relates to antigens, associated with sterile immunity, and methods of their use, in an immunogenic formulation to confer an immune response against | 03-24-2016 |
20160083439 | NOVEL VACCINES AGAINST APICOMPLEXAN PATHOGENS - The technology provided herein generally relates to novel fusion proteins suitable as human and/or animal vaccines against parasites or pathogens of the phylum Apicomplexa. In particular, the present disclosure relates to novel fusion proteins as a basis for vaccines against | 03-24-2016 |
20160120975 | FISH VACCINE - A composition comprising a translocation sequence derived from a fish pathogen and a heterologous payload coupled to the translocation sequence is provided. The composition is able to translocate across the plasma membrane of a eukaryotic cell, for example a fish cell, and thus stimulate an immune response. Accordingly, nucleic acids, vectors, host cells, compositions and vaccines based thereon are also provided. | 05-05-2016 |
20160129099 | TREATMENT AND PREVENTION OF MALARIA - There are provided antigens, vectors encoding the antigens, and antibodies and other binding compounds to the antigens and uses thereof in the prevention or treatment of malaria. In particular, compositions are provided comprising a Reticulocyte-binding protein Homologue 5 (PfRH5) antigen having at least 90% identity with SEQ ID NO: 1, or a fragment thereof; or which comprise a viral vector that expresses PfRH5 antigen having at least 90% identity with SEQ ID NO: 2, or a fragment thereof. | 05-12-2016 |
20160136253 | VACCINES AGAINST PREGNANCY-ASSOCIATED MALARIA - The present invention relates to combinations of polypeptides or of polynucleotides corresponding to a specific region of the N-terminal portion of the VAR2CSA protein of different parasitic families or lines of | 05-19-2016 |
20160158329 | VACCINES COMPRISING LEISHMANIA POLYPEPTIDES FOR THE TREATMENT AND DIAGNOSIS OF LEISHMANIASIS - Compositions and methods for preventing, treating and detecting leishmaniasis are disclosed. The compositions generally comprise polypeptides comprising one or more | 06-09-2016 |
20160193316 | Inducing Cellular Immune Responses to Plasmodium Falciparum Using Peptide and Nucleic Acid Compositions | 07-07-2016 |
20170232091 | NOVEL ANTIGEN FOR USE IN MALARIA | 08-17-2017 |
20170234872 | In Vivo Induced Toxoplasma Gondii Protein For Application In Diagnosis, Vaccine And Therapy | 08-17-2017 |
20190142916 | BIOMARKERS AND IMMUNOGENIC COMPOSITIONS FOR FILARIAL PARASITES | 05-16-2019 |