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Polymer from ethylenic monomers only

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424 - Drug, bio-affecting and body treating compositions


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Class / Patent application numberDescriptionNumber of patent applications / Date published
424780350 Nitrogen or sulfur containing monomer 27
424780320 Heterocyclic monomer 23
20090196848ABSORBENT INGESTIBLE AGENTS AND ASSOCIATED METHODS OF MANUFACTURE AND USE - Appetite suppression and weight management achieved through pre-meal ingestion of temporary gastric bulking agents in the form of superabsorbent polymer hydrogels (SAPHs) selected from among a group consisting of crosslinked polycarboxylic acid moieties is described. The preferred compositions and manufacturing methods of ultrapure preparations of ingestible forms; as well as the preferred methods of use, dosage and administration; distribution and delivery of SAPH materials are also described.08-06-2009
20080260679METHODS AND COMPOSITIONS FOR TREATMENT OF ION IMBALANCES - The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising sodium-binding polymers and pharmaceutical compositions thereof. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of hypertension, chronic heart failure, end stage renal disease, liver cirrhosis, chronic renal insufficiency, fluid overload, or sodium overload.10-23-2008
20080260678MOLECULAR BAND-AID - A molecular sealant comprising a therapeutically effective amount of a poloxamer capable of sealing a cell or tissue from leaks. A method of treating tissue leakages by applying the above sealant to the tissue or cell in need of treatment. A composition for treating cellular leakages comprising a poloxamer capable of sealing a cell or tissue from leaks in a pharmaceutically acceptable carrier.10-23-2008
20100119472COMPOSITION FOR COMBATING EPISTAXIS - The invention relates to a gel composition comprising: a) a carboxy polymethylene polymer; b) glycine; c) a source of calcium ions; and d) water. The invention also extends to a dry composition comprising the aforementioned components a), b) and c). The gel compositions of the invention are useful for the prophylaxis and treatment of epistaxis. The gel compositions can be easily administered to the nasal cavity and do not require removal after use.05-13-2010
20100034770ANTIMICROBIAL SURFACES - The present invention relates to compositions having a light activated antimicrobial material connected to an environmental surface, such as fabric, through a linking moiety and a mediator polymer. Also taught herein are surfaces to which the compositions of this invention are attached to impart antimicrobial activity to those surfaces. The present invention facilitates or makes possible the attachment of certain light activated antimicrobial material such as Rose Bengal dye to a surface to achieve antimicrobial activity.02-11-2010
20130084262REPAIRING BRUCH'S MEMBRANE WITH HYDROGELS - The invention provides hydrogels and methods for their use in treating disorders of the retina such as age-related macular degeneration (AMD).04-04-2013
20090304622METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS - The present invention refers to a method of infiltrating enamel for the prevention and/or treatment of carious lesions comprising (a) exposing an enamel area to a conditioner comprising hydrochloric acid; (b) exposing the conditioned enamel area to an infiltrant; and (c) curing the infiltrant. The present invention further refers to a kit for carrying out the method of infiltrating enamel, which comprises a conditioner comprising hydrochloric acid and an infiltrant comprising at least one low viscous dental resin. Alternatively, the kit comprises ready-to-use means for carrying out the method of infiltrating enamel, e.g. application strips with delivery pads soaked with conditioner or infiltrant. The present invention also refers to a method for identifying an infiltrant by calculation of the penetration coefficient, and to an infiltrant identified by the method having a penetration coefficient of >50 cm/s or comprising a low viscous light curing resin having a penetration coefficient of >50 cm/s.12-10-2009
20090304621Biofilm Resistant Polymer Materials - The present invention relates to compounds and materials that reduce the accumulation of microorganisms on a surface by interfering with the attachment of the organisms to the surface. The compounds and materials of the present invention are thus useful in preventing the formation of biofilms. The compounds of the present invention may be either adhered to a surface or integrated within a polymer. Surfaces coated by the present invention are resistant to biofilm formation, in part due to the smoothness of the surface coated with the present invention.12-10-2009
20090010870Hydrophobic Flourinated Polymer Surfaces - The invention at hand concerns hydrophobic polymer surfaces, in particular superhydrophobic polymer surfaces, comprising at least one homo- or copolymer, which comprises at least one side chain with at least one fluoro-substituted aryl group. Furthermore, the invention at hand concerns a method for the production of polymer surfaces of this type, their use and polymers of the general formula I:01-08-2009
20100074859SKIN CARE COMPOSITIONS AND RELATED METHODS - A skin care composition comprising an acrylate polymer; a yield value increaser, and a surfactant. The composition has a yield value of at least about 4. Also included within the scope of the invention are related methods, such as methods of depositing a hydrophobic material on an epidermal surface and methods of incorporating a hydrophobic material into a skin care composition.03-25-2010
20110280825EXTRACORPOREAL DEVICES AND METHODS OF TREATING COMPLICATIONS OF PREGNANCY - The invention features extracorporeal methods for the treatment of a subject having a pregnancy related hypertensive disorder, such as pre-eclampsia or eclampsia. The invention also features devices used for the extracorporeal treatment of subjects have a pregnancy related hypertensive disorder, such as pre-eclampsia or eclampsia.11-17-2011
20100143286Preparation of functional gel particles with a dual crosslink network - Functional gel particle formed from a crosslinked polymeric network including a fraction of stable crosslinks and a second fraction of cleavable crosslinks are disclosed. Functional compounds may be chemically or physically encapsulated within and/or released from the gel particle by selective cleavage of the cleavable crosslinks. The functional compounds may be delivered and released to a pre-selected target site. Peripheral or other accessible functionality on the surface of the gel particle allows attachment of a surface reactive agent, thereby modifying one or more surface properties of the gel particle. Processes of preparing the gel particles and processes of delivering the functional compounds to a target site are also disclosed.06-10-2010
20080206187METHOD FOR TREATING A NEOPLASTIC DISORDER - A method for treating a neoplastic disorder in a subject includes administering to the neoplastic cells a neoplastic cell-sensitizing composition including a poly(ethylene oxide)-poly(propylene oxide) copolymer. The poly(ethylene oxide)-poly(propylene oxide) copolymer can sensitize the neoplastic cells to hyperthermia. Energy can be applied to the neoplastic cells to heat and ablate the cells.08-28-2008
20080286224Use of a Lotion Composition on an Absorbent Article for Reducing Adherence of Feces or Menses to the Skin - The present invention relates to lotion compositions comprised on a body facing surface of an absorbent article such as a diaper, training pants or adult incontinence product. The lotion composition reduces the adherence of feces or menses to the human skin. The lotion composition comprises at least two compounds wherein one first compound is liquid at 25° C. and at least one second component which is solid at 25° C. An effective amount of the lotion composition is comprised on a body facing surface of an absorbent article which is intended to be worn by a wearer.11-20-2008
20080286223Compositions Having a High Antiviral and Antibacterial Efficacy - Antimicrobial compositions having a rapid antiviral and antibacterial effectiveness, and a persistent antiviral effectiveness, are disclosed. The antimicrobial compositions contain (a) a disinfecting alcohol, (b) an organic acid, and (c) water, wherein the composition has a pH of about 5 or less.11-20-2008
20100284958BoNT/A Peptides and Methods of Predicting and Reducing Immunoresistance to Botulinum Toxin Therapy - The present invention provides BoNT/A peptides as well as methods of predicting or determining immunoresistance to botulinum toxin therapy in an individual using BoNT/A peptides.11-11-2010
20080206186Pro-Angiogenic Polymer Scaffolds - A pro-angiogenic porous polymer scaffold is disclosed. The polymer has at least 20 mol-% monomeric subunits containing acidic functional groups, and has a porosity of at least 40%. The pores in the scaffold are interconnected. A method of making such a scaffold using a novel adaptation to the traditional solvent casting/particulate leaching technique is also disclosed. The scaffold may be used for tissue regeneration.08-28-2008
20090081153COMBINATION OF SYNTHETIC ANTIMICROBIAL POLYMERS AND SESQUITERPENOID COMPOUNDS - The present invention provides compositions comprising a synthetic antimicrobial polymer and/or oligomer and a sesquiterpenoid compound useful in reducing the growth of microbes.03-26-2009
20110223128REGULATION OF MICROVASCULATURE OCCLUSION - The present invention provides compositions and methods to regulate embolic occlusion of the microvasculature. In particular, the present invention inhibits extravasation of emboli from microvasculature resulting in increased occlusion (e.g., by administering a MMP 2/9 inhibitor locally to a subject).09-15-2011
20120195848STRONTIUM-CONTAINING BIOACTIVE BONE CEMENT - The present invention provides bioactive bone cements that not only have sufficient radiopacity, low physiological toxicity, and requisite mechanism strength, but also promote local bone in-growth. The bone cement utilizes strontium salts as radiopacifiers, and comprises a powder component and a liquid component. In an embodiment, the powder component comprises a strontium salt, poly(methyl methacrylate) (PMMA), and a polymerization initiator; and the liquid component comprises methyl methacrylate (MMA) as reactive monomers and a polymerization accelerator.08-02-2012
20090117070Methods and Crosslinked Polymer Compositions for Cartilage Repair - A method of repairing damaged cartilage and soft tissue in a patient is provided using a biocompatible, non-immunogenic composition. The composition comprises a hydrophilic polymer and a plurality of crosslinkable components having reactive functional groups. The composition used in the method may be loaded with biologically active agents for delivery to the damaged tissues. Kits for use in carrying out the method of the invention are also provided.05-07-2009
20090252701Biostatic Polymer - Methods and compositions effective for at least a week for prevention of microbial colony growth on a surface, for example an inanimate surface, where the surface is covered with a dry or substantially dry film formed from a composition comprising a polyvinyl alcohol and a quaternary ammonium compound. The film may be formed in situ by coating the surface with a solution or emulsion comprising a polyvinyl alcohol and a quaternary ammonium compound and then causing or allowing it to dry or substantially dry.10-08-2009
20110236344Synthetic mimics of mammalian cell surface receptors: method and compositions - The present invention relates to new synthetic receptors. More particularly, the present invention relates to the use of the synthetic receptors for delivering a protein, peptide, drug, prodrug, lipid, nucleic acid, carbohydrate or small molecule into a target cell via receptor-mediated endocytosis. According to the invention, novel synthetic mimics of cell surface receptors have been designed and methods for use of the same are disclosed.09-29-2011
20090035251METHOD OF APPLYING AN INJECTABLE FILLER - Methods for applying injectable fillers are provided. In some embodiments, the methods can extend effectiveness of the injectable filler. In some embodiments, the methods can provide for an elevated level of effectiveness of the injectable filler. In some embodiments, the methods can prolong the effectiveness of the injectable filler.02-05-2009
20090035250Compositions and methods for treating cavity conditions - Compositions, methods and kits to be used as a lubricant and for treatment of a cavity pathology including joint pathology are provided. The composition comprises therapeutically effective amounts of at least one bioactive agent, such as magnesium compound, at least one lubricating agent, such as hyaluronic acid, and at least one cell membrane repairing agent, such as polyethylene glycol. The components of these compositions may be administered by a direct application, an application through a cannula, an intra-articular injection, as a flush fluid during an arthroscopy of the affected area, as a post-arthroscopy injection, or as part of a lavage of the area affected by the intra-articular pathology. In addition, the composition of the present invention may be administered to the patient from a pump or a depot.02-05-2009
20100178270METAL SALT NANOGEL-CONTAINING POLYMERS - The invention relates to a method for producing metal salt nanogel-containing aqueous dispersions, solid intermediate products and waterproof plastic products, thus allowing the simple production of novel products having homogeneously distributed agents, which exhibit, for example, an antimicrobial or barrier effect and/or have an absorbing capacity, such as with respect to oxygen, humidity, chemical, particularly gaseous compounds, or electromagnetic or radioactive radiation.07-15-2010
20110177021COMPOSITION FOR FORMING A TEMPORARY OBSTRUCTION AND METHOD OF FORMING THE SAME - The present invention relates to a method for forming a temporary obstruction of the intestine of a mammal, using a solidifiable composition, said composition being flow-able and solidifiable to form a solid plug at a desired site within the intestine, the structure of said plug being changeable in order to allow for the subsequent, at least partial removal of the obstruction.07-21-2011
20090317355ABUSE RESISTANT MELT EXTRUDED FORMULATION HAVING REDUCED ALCOHOL INTERACTION - The present invention relates to compositions for oral administration. The invention preferably comprises at least one abuse-resistant drug delivery composition for delivering a drug having potential for dose dumping in alcohol, related methods of preparing these dosage forms, and methods of treating a patient in need thereof comprising administering the inventive compositions to the patient. Most preferably, the dosage form includes verapamil. These formulations have reduced potential for abuse. In another formulation, preferably the abuse relevant drug is an opioid and the non-abuse relevant drug is acetaminophen or ibuprofen. More preferably, the opioid is hydrocodone, and the non-abuse relevant analgesic is acetaminophen. In certain preferred embodiments, the dosage forms are characterized by resistance to solvent extraction; tampering, crushing or grinding. Certain embodiments of the inventions provide dosage forms that provide an initial burst of release of drug followed by a prolonged period of controllable drug release.12-24-2009
20080267902BLOOD PRODUCTS WITH BINDING AGENT - The present invention provides a non-liquid biomaterial that may be used as a surgical sealant, a suture support, a blood flow controller, an adhesion reducing agent, an adhesion preventing agent, a tissue support, a tissue filler, a wound dressing or a combination thereof. The non-liquid biomaterial may comprise a blood derived material such as plasma, platelet poor plasma, platelet rich plasma or a material derived from blood containing tissue aspirate, such as bone marrow aspirate, a protein binding agent and a polymerizing agent. Methods for making and using the non-liquid biomaterial are also provided.10-30-2008
20110135593STERILIZING POLYMER AND METHOD OF PREPARATION THEREOF - The present invention provided a polymer and a method for preparing the polymer, wherein the polymer was a terpolymer having a molecular weight of more than 1000, and copolymerized by acrolein, acrylic acid, and low alkene-alkyl dibasic acid or low-alkene-alkyl polybasic acid.06-09-2011
20090074708Inhibitors and Enhancers of Uridine Diphosphate-Glucuronosyltransferase 2B (UGT2B) - A UGT2B inhibitor capable of increasing the bio-availability of a drug, is a compound in a free base or a pharmaceutically acceptable salt form that is selected from the group consisting of: capillarisin, isorhamnetin, β-naphthoflavone, α-naphthoflavone, hesperetin, terpineol, (+)-limonene, β-myrcene, swertiamarin, eriodictyol, cineole, apigenin, baicalin, ursolic acid, isovitexin, lauryl alcohol, puerarin, trans-cinnamaldehyde, 3-phenylpropyl acetate, isoliquritigenin, paeoniflorin, gallic acid, genistein, glycyrrhizin, protocatechuic acid, ethyl myristate, umbelliferone, PEG (Polyethylene glycol) 400, PEG 2000, PEG 4000, Tween 20, Tween 60, Tween 80, BRIJ® 58, BRIJ® 76, Pluronic® F68, Pluronic® F127, and a combination thereof. A UGT2B enhancer capable of enhancing a clearance rate of morphine-like analgesic agents, is a compound in a free base or a pharmaceutically acceptable salt form that is selected from the group consisting of: nordihydroguaiaretic acid, wogonin, trans-cinnamic acid, baicalein, quercetin, daidzein, oleanolic acid, homoorientin, hesperetin, narigin, neohesperidin, (+)-epicatechin, hesperidin, liquiritin, eriodictyol, formononetin, quercitrin, genkwanin, kaempferol, isoquercitrin, (+)-catechin, naringenin, daidzin, (−)-epicatechin, luteolin-7-glucoside, ergosterol, rutin, luteolin, ethyl myristate, apigenin, 3-phenylpropyl acetate, umbelliferone, glycyrrhizin, protocatechuic acid, poncirin, isovitexin, 6-gingerol, cineole, genistein, trans-cinnamaldehyde, and a combination thereof.03-19-2009
20100209382Polyphenol Conjugates as RGD-Binding Compounds and Methods of Use - Provided herein are compositions and methods for preventing and treating diseases and risk factors associated with metabolic syndrome by targeting the RGD-binding site of selected intra- and extracellular proteins. Exemplary compositions include RGD-polyphenol conjugates via an ester linkage; polyphenol polymer conjugated to RGD analogs or mimetics; and RGD polymer conjugates linked to polyphenol.08-19-2010
20120003177CURCUMIN-CONTAINING POLYMERS AND WATER-SOLUBLE CURCUMIN DERIVATIVES AS PRODRUGS OF PRODRUG CARRIERS - Curcumin, a polyphenol extracted from the rhizome turmeric, has been polymerized to produce a polymer material having a backbone of one or more repeating structural units, at least one of which comprises a curcumin monomer residue. These curcumin-containing polymers have a wide range of pharmacological activities, including, among others antitumor, antioxidant, antiinflammatory, antithrombotic and antibacterial activities. Certain species of these polymers have exhibited remarkable antitumor activity. Water-soluble curcumin derivatives and their use as prodrugs and prodrug carriers are also disclosed.01-05-2012
20120082637Lacquer Composition Comprising a Monomer with a Polyalicyclic Structure Element - A transparent lacquer composition that can be used as a protective and gloss lacquer for surface coating is described. The lacquer composition can be a dental material and a method for preparing a lacquer composition is also described. Also described are novel polymerizable monomers comprising at least one polyalicyclic structure element and certain ethylenic structure elements that are particularly suitable for use in a lacquer composition.04-05-2012
20080226584ANTIMICROBIAL AND ANTISTATIC POLYMERS AND METHODS OF USING SUCH POLYMERS ON VARIOUS SUBSTRATES - The present invention relates to a substrate having one or more antimicrobial or antistatic properties. Such properties are imparted by applying a coating or film formed from a cationically-charged polymer composition. The polymer composition includes a noncationic ethylenically unsaturated monomer and an ethylenically unsaturated monomer capable of providing a cationic charge to the polymer composition. Optionally, the polymer composition includes a steric stabilization component incorporated into the cationically-charged polymer composition. The present invention also relates to a personal care product and polymeric material comprising a base polymer blended with the above cationically-charged polymer composition.09-18-2008
20130177524METHODS FOR ENHANCING OXYGENATION OF JEOPARDIZED TISSUE - The present invention provides methods for preventing the adverse effects of transfusing a patient with blood or blood products compromised by storage lesion. The methods include administering to a patient a pharmaceutical composition comprising an effective amount of a polyoxyethylene/polyoxypropylene copolymer and a pharmaceutically acceptable carrier. The safety and effectiveness of transfusing blood with storage lesion can be increased using the methods of the invention.07-11-2013
20080213210Method to purify poly(vinyl alcohol) - Disclosed herein is a process to produce a film comprising poly(vinyl alcohol), wherein the poly (vinyl alcohol) solution has been purified utilizing an ion exchange resin. An approximate 50 micrometer thick film produced from the purified aqueous poly(vinyl alcohol) solution has an APHA color value of 50 or less after the film has been heated at 150° C. for 60 minutes.09-04-2008
20080213209Process for Producing Cross-Linked Material of Polylactic Acid and Cross-Linked Material of Polylactic Acid - A cross-linked material of polylactic acid produced by preparing a polylactic acid composition by mixing polylactic acid with at least a plasticizer containing either a rosin derivative or a dicarboxylic acid derivative and/or a glycerin derivative and cross-linking monomer, and kneading the resulting mixture; preparing a polylactic acid molded product by molding the composition into a desired shape; and then cross-linking the molded product by irradiation of ionizing radiation.09-04-2008
20110243883POLYMERIC BIOLUBRICANTS FOR MEDICAL USE - The present invention provides branched polymers which can be used as lubricants or shock absorbers in vivo. For example, the inventive polymers can be used as viscosupplements, viscoelastics, tissue space fillers, and/or anti-adhesive agents. Also provided are pharmaceutical compositions comprising the inventive polymers and methods of using them including, for example, in the treatment of arthritic and sport-injured knee joints; in reconstruction or cosmetic procedures, intervertebral disc repair, treatment of vocal cord problems, treatment of urinary incontinence, and prevention of adhesion formation following abdominal or gynecological surgery.10-06-2011
20110243882ANTIBACTERIAL POLYMER EMULSION AND COATING COMPOSITION - An aqueous antibacterial polymer emulsion and coating compositions are provided. The aqueous antibacterial polymer emulsion comprising a polymer A, an oxidant and a metal complexed with a copolymer B comprising heterocyclic containing monomers; wherein the metal is selected from copper, silver, gold, tin, zinc and combinations thereof; and wherein the emulsion is heat stable. The coating compositions made therefrom provide persistent, broad spectrum antibacterial activity without discoloration problem upon exposure to heat and/or sun light.10-06-2011
20130156724USE OF POLOXAMINESINES AS INDUCERS OF THE OSTEOGENIC DIFFERENTIATION OF MESENCHYMAL CELLS - The invention describes for first time the activity of poloxamines as inducers in the differentiation of mesenchymal or progenitor cells. In particular, the invention demonstrates that poloxamines have an osteogenic ability. The invention relates to the use of one or more poloxamines or a pharmaceutical composition comprising same for the preparation of a drug for treting patients with bone defects in general. The invention also relates to a method for inducing the differentiation of mesenchymal or progenitor cells into osteoblasts by bringing said cells into contact with a sterilised aqueous dispersion or solution of one or more poloxamines.06-20-2013
20120282212AQUEOUS OLIGOMER/POLYMER EMULSION WITH CATIONIC FUNCTIONALITY - An aqueous emulsion comprising at least a covalently bound vinyl oligomer and vinyl polymer, wherein said vinyl oligomer comprises 5 to 85 mol % of vinyl monomers bearing quaternary ammonium ion functional groups or quaternisable amine functional groups and is obtained by a controlled radical polymerisation of at least one vinyl monomer via a reversible addition-fragmentation chain transfer mechanism in solution in the presence of a control agent and a source of free radicals; wherein said vinyl polymer is obtained by emulsion polymerisation of vinyl monomers in the presence of the vinyl oligomer; wherein the weight % ratio of vinyl oligomer to vinyl polymer is in the range of from 0.5:99.5 to 65:35.11-08-2012
20090081152ANTIMICROBIAL COMPOSITIONS AND METHODS OF MAKING SAME - This invention relates to a process of making a group of silylated poly(N-alkyl-4-vinylpyridinium) quaternized salts suitable for use as coating materials for the treatment of substrate surfaces to impart an antimicrobial effect.03-26-2009
20120027715POLYMER FILMS WITH EMBEDDED IODINATED RESIN AND METHODS OF MANUFACTURING SAME - The disclosure relates to polymer films containing iodinated resin, where such films have advantageous antibacterial and/or antitoxic properties. The films may be used, for example, in medical tape, wound dressings and bandages. In certain embodiments, the invention is also directed to methods of manufacturing such polymer films, where various manufacturing difficulties have been addressed and overcome.02-02-2012
20130195792METHOD OF TREATING INFLAMMATION - The present invention concerns methods of treating systemic, regional, or local inflammation from a patient suffering or at risk of inflammation comprising administration of a therapeutically effective dose of a sorbent that sorbs an inflammatory mediator in said patient. In some preferred embodiments, the sorbent is a biocompatible organic polymer.08-01-2013

Patent applications in class Polymer from ethylenic monomers only

Patent applications in all subclasses Polymer from ethylenic monomers only