| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 424780310 | Polymer from ethylenic monomers only | 88 |
| 20090196848 | ABSORBENT INGESTIBLE AGENTS AND ASSOCIATED METHODS OF MANUFACTURE AND USE - Appetite suppression and weight management achieved through pre-meal ingestion of temporary gastric bulking agents in the form of superabsorbent polymer hydrogels (SAPHs) selected from among a group consisting of crosslinked polycarboxylic acid moieties is described. The preferred compositions and manufacturing methods of ultrapure preparations of ingestible forms; as well as the preferred methods of use, dosage and administration; distribution and delivery of SAPH materials are also described. | 08-06-2009 |
| 20100119472 | COMPOSITION FOR COMBATING EPISTAXIS - The invention relates to a gel composition comprising: a) a carboxy polymethylene polymer; b) glycine; c) a source of calcium ions; and d) water. The invention also extends to a dry composition comprising the aforementioned components a), b) and c). The gel compositions of the invention are useful for the prophylaxis and treatment of epistaxis. The gel compositions can be easily administered to the nasal cavity and do not require removal after use. | 05-13-2010 |
| 20100074859 | SKIN CARE COMPOSITIONS AND RELATED METHODS - A skin care composition comprising an acrylate polymer; a yield value increaser, and a surfactant. The composition has a yield value of at least about 4. Also included within the scope of the invention are related methods, such as methods of depositing a hydrophobic material on an epidermal surface and methods of incorporating a hydrophobic material into a skin care composition. | 03-25-2010 |
| 20100034770 | ANTIMICROBIAL SURFACES - The present invention relates to compositions having a light activated antimicrobial material connected to an environmental surface, such as fabric, through a linking moiety and a mediator polymer. Also taught herein are surfaces to which the compositions of this invention are attached to impart antimicrobial activity to those surfaces. The present invention facilitates or makes possible the attachment of certain light activated antimicrobial material such as Rose Bengal dye to a surface to achieve antimicrobial activity. | 02-11-2010 |
| 20130084262 | REPAIRING BRUCH'S MEMBRANE WITH HYDROGELS - The invention provides hydrogels and methods for their use in treating disorders of the retina such as age-related macular degeneration (AMD). | 04-04-2013 |
| 20090304622 | METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS - The present invention refers to a method of infiltrating enamel for the prevention and/or treatment of carious lesions comprising (a) exposing an enamel area to a conditioner comprising hydrochloric acid; (b) exposing the conditioned enamel area to an infiltrant; and (c) curing the infiltrant. The present invention further refers to a kit for carrying out the method of infiltrating enamel, which comprises a conditioner comprising hydrochloric acid and an infiltrant comprising at least one low viscous dental resin. Alternatively, the kit comprises ready-to-use means for carrying out the method of infiltrating enamel, e.g. application strips with delivery pads soaked with conditioner or infiltrant. The present invention also refers to a method for identifying an infiltrant by calculation of the penetration coefficient, and to an infiltrant identified by the method having a penetration coefficient of >50 cm/s or comprising a low viscous light curing resin having a penetration coefficient of >50 cm/s. | 12-10-2009 |
| 20090304621 | Biofilm Resistant Polymer Materials - The present invention relates to compounds and materials that reduce the accumulation of microorganisms on a surface by interfering with the attachment of the organisms to the surface. The compounds and materials of the present invention are thus useful in preventing the formation of biofilms. The compounds of the present invention may be either adhered to a surface or integrated within a polymer. Surfaces coated by the present invention are resistant to biofilm formation, in part due to the smoothness of the surface coated with the present invention. | 12-10-2009 |
| 20090010870 | Hydrophobic Flourinated Polymer Surfaces - The invention at hand concerns hydrophobic polymer surfaces, in particular superhydrophobic polymer surfaces, comprising at least one homo- or copolymer, which comprises at least one side chain with at least one fluoro-substituted aryl group. Furthermore, the invention at hand concerns a method for the production of polymer surfaces of this type, their use and polymers of the general formula I: | 01-08-2009 |
| 20110280825 | EXTRACORPOREAL DEVICES AND METHODS OF TREATING COMPLICATIONS OF PREGNANCY - The invention features extracorporeal methods for the treatment of a subject having a pregnancy related hypertensive disorder, such as pre-eclampsia or eclampsia. The invention also features devices used for the extracorporeal treatment of subjects have a pregnancy related hypertensive disorder, such as pre-eclampsia or eclampsia. | 11-17-2011 |
| 20080213210 | Method to purify poly(vinyl alcohol) - Disclosed herein is a process to produce a film comprising poly(vinyl alcohol), wherein the poly (vinyl alcohol) solution has been purified utilizing an ion exchange resin. An approximate 50 micrometer thick film produced from the purified aqueous poly(vinyl alcohol) solution has an APHA color value of 50 or less after the film has been heated at 150° C. for 60 minutes. | 09-04-2008 |
| 20100143286 | Preparation of functional gel particles with a dual crosslink network - Functional gel particle formed from a crosslinked polymeric network including a fraction of stable crosslinks and a second fraction of cleavable crosslinks are disclosed. Functional compounds may be chemically or physically encapsulated within and/or released from the gel particle by selective cleavage of the cleavable crosslinks. The functional compounds may be delivered and released to a pre-selected target site. Peripheral or other accessible functionality on the surface of the gel particle allows attachment of a surface reactive agent, thereby modifying one or more surface properties of the gel particle. Processes of preparing the gel particles and processes of delivering the functional compounds to a target site are also disclosed. | 06-10-2010 |
| 20080206187 | METHOD FOR TREATING A NEOPLASTIC DISORDER - A method for treating a neoplastic disorder in a subject includes administering to the neoplastic cells a neoplastic cell-sensitizing composition including a poly(ethylene oxide)-poly(propylene oxide) copolymer. The poly(ethylene oxide)-poly(propylene oxide) copolymer can sensitize the neoplastic cells to hyperthermia. Energy can be applied to the neoplastic cells to heat and ablate the cells. | 08-28-2008 |
| 20080213209 | Process for Producing Cross-Linked Material of Polylactic Acid and Cross-Linked Material of Polylactic Acid - A cross-linked material of polylactic acid produced by preparing a polylactic acid composition by mixing polylactic acid with at least a plasticizer containing either a rosin derivative or a dicarboxylic acid derivative and/or a glycerin derivative and cross-linking monomer, and kneading the resulting mixture; preparing a polylactic acid molded product by molding the composition into a desired shape; and then cross-linking the molded product by irradiation of ionizing radiation. | 09-04-2008 |
| 20080286224 | Use of a Lotion Composition on an Absorbent Article for Reducing Adherence of Feces or Menses to the Skin - The present invention relates to lotion compositions comprised on a body facing surface of an absorbent article such as a diaper, training pants or adult incontinence product. The lotion composition reduces the adherence of feces or menses to the human skin. The lotion composition comprises at least two compounds wherein one first compound is liquid at 25° C. and at least one second component which is solid at 25° C. An effective amount of the lotion composition is comprised on a body facing surface of an absorbent article which is intended to be worn by a wearer. | 11-20-2008 |
| 20080286223 | Compositions Having a High Antiviral and Antibacterial Efficacy - Antimicrobial compositions having a rapid antiviral and antibacterial effectiveness, and a persistent antiviral effectiveness, are disclosed. The antimicrobial compositions contain (a) a disinfecting alcohol, (b) an organic acid, and (c) water, wherein the composition has a pH of about 5 or less. | 11-20-2008 |
| 20100284958 | BoNT/A Peptides and Methods of Predicting and Reducing Immunoresistance to Botulinum Toxin Therapy - The present invention provides BoNT/A peptides as well as methods of predicting or determining immunoresistance to botulinum toxin therapy in an individual using BoNT/A peptides. | 11-11-2010 |
| 20080206186 | Pro-Angiogenic Polymer Scaffolds - A pro-angiogenic porous polymer scaffold is disclosed. The polymer has at least 20 mol-% monomeric subunits containing acidic functional groups, and has a porosity of at least 40%. The pores in the scaffold are interconnected. A method of making such a scaffold using a novel adaptation to the traditional solvent casting/particulate leaching technique is also disclosed. The scaffold may be used for tissue regeneration. | 08-28-2008 |
| 20090081153 | COMBINATION OF SYNTHETIC ANTIMICROBIAL POLYMERS AND SESQUITERPENOID COMPOUNDS - The present invention provides compositions comprising a synthetic antimicrobial polymer and/or oligomer and a sesquiterpenoid compound useful in reducing the growth of microbes. | 03-26-2009 |
| 20090081152 | ANTIMICROBIAL COMPOSITIONS AND METHODS OF MAKING SAME - This invention relates to a process of making a group of silylated poly(N-alkyl-4-vinylpyridinium) quaternized salts suitable for use as coating materials for the treatment of substrate surfaces to impart an antimicrobial effect. | 03-26-2009 |
| 20110223128 | REGULATION OF MICROVASCULATURE OCCLUSION - The present invention provides compositions and methods to regulate embolic occlusion of the microvasculature. In particular, the present invention inhibits extravasation of emboli from microvasculature resulting in increased occlusion (e.g., by administering a MMP 2/9 inhibitor locally to a subject). | 09-15-2011 |
| 20080260679 | METHODS AND COMPOSITIONS FOR TREATMENT OF ION IMBALANCES - The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising sodium-binding polymers and pharmaceutical compositions thereof. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of hypertension, chronic heart failure, end stage renal disease, liver cirrhosis, chronic renal insufficiency, fluid overload, or sodium overload. | 10-23-2008 |
| 20080260678 | MOLECULAR BAND-AID - A molecular sealant comprising a therapeutically effective amount of a poloxamer capable of sealing a cell or tissue from leaks. A method of treating tissue leakages by applying the above sealant to the tissue or cell in need of treatment. A composition for treating cellular leakages comprising a poloxamer capable of sealing a cell or tissue from leaks in a pharmaceutically acceptable carrier. | 10-23-2008 |
| 20120195848 | STRONTIUM-CONTAINING BIOACTIVE BONE CEMENT - The present invention provides bioactive bone cements that not only have sufficient radiopacity, low physiological toxicity, and requisite mechanism strength, but also promote local bone in-growth. The bone cement utilizes strontium salts as radiopacifiers, and comprises a powder component and a liquid component. In an embodiment, the powder component comprises a strontium salt, poly(methyl methacrylate) (PMMA), and a polymerization initiator; and the liquid component comprises methyl methacrylate (MMA) as reactive monomers and a polymerization accelerator. | 08-02-2012 |
| 20090117070 | Methods and Crosslinked Polymer Compositions for Cartilage Repair - A method of repairing damaged cartilage and soft tissue in a patient is provided using a biocompatible, non-immunogenic composition. The composition comprises a hydrophilic polymer and a plurality of crosslinkable components having reactive functional groups. The composition used in the method may be loaded with biologically active agents for delivery to the damaged tissues. Kits for use in carrying out the method of the invention are also provided. | 05-07-2009 |
| 20090252701 | Biostatic Polymer - Methods and compositions effective for at least a week for prevention of microbial colony growth on a surface, for example an inanimate surface, where the surface is covered with a dry or substantially dry film formed from a composition comprising a polyvinyl alcohol and a quaternary ammonium compound. The film may be formed in situ by coating the surface with a solution or emulsion comprising a polyvinyl alcohol and a quaternary ammonium compound and then causing or allowing it to dry or substantially dry. | 10-08-2009 |
| 20110236344 | Synthetic mimics of mammalian cell surface receptors: method and compositions - The present invention relates to new synthetic receptors. More particularly, the present invention relates to the use of the synthetic receptors for delivering a protein, peptide, drug, prodrug, lipid, nucleic acid, carbohydrate or small molecule into a target cell via receptor-mediated endocytosis. According to the invention, novel synthetic mimics of cell surface receptors have been designed and methods for use of the same are disclosed. | 09-29-2011 |
| 20110243883 | POLYMERIC BIOLUBRICANTS FOR MEDICAL USE - The present invention provides branched polymers which can be used as lubricants or shock absorbers in vivo. For example, the inventive polymers can be used as viscosupplements, viscoelastics, tissue space fillers, and/or anti-adhesive agents. Also provided are pharmaceutical compositions comprising the inventive polymers and methods of using them including, for example, in the treatment of arthritic and sport-injured knee joints; in reconstruction or cosmetic procedures, intervertebral disc repair, treatment of vocal cord problems, treatment of urinary incontinence, and prevention of adhesion formation following abdominal or gynecological surgery. | 10-06-2011 |
| 20090035251 | METHOD OF APPLYING AN INJECTABLE FILLER - Methods for applying injectable fillers are provided. In some embodiments, the methods can extend effectiveness of the injectable filler. In some embodiments, the methods can provide for an elevated level of effectiveness of the injectable filler. In some embodiments, the methods can prolong the effectiveness of the injectable filler. | 02-05-2009 |
| 20090035250 | Compositions and methods for treating cavity conditions - Compositions, methods and kits to be used as a lubricant and for treatment of a cavity pathology including joint pathology are provided. The composition comprises therapeutically effective amounts of at least one bioactive agent, such as magnesium compound, at least one lubricating agent, such as hyaluronic acid, and at least one cell membrane repairing agent, such as polyethylene glycol. The components of these compositions may be administered by a direct application, an application through a cannula, an intra-articular injection, as a flush fluid during an arthroscopy of the affected area, as a post-arthroscopy injection, or as part of a lavage of the area affected by the intra-articular pathology. In addition, the composition of the present invention may be administered to the patient from a pump or a depot. | 02-05-2009 |
| 20110243882 | ANTIBACTERIAL POLYMER EMULSION AND COATING COMPOSITION - An aqueous antibacterial polymer emulsion and coating compositions are provided. The aqueous antibacterial polymer emulsion comprising a polymer A, an oxidant and a metal complexed with a copolymer B comprising heterocyclic containing monomers; wherein the metal is selected from copper, silver, gold, tin, zinc and combinations thereof; and wherein the emulsion is heat stable. The coating compositions made therefrom provide persistent, broad spectrum antibacterial activity without discoloration problem upon exposure to heat and/or sun light. | 10-06-2011 |
| 20100178270 | METAL SALT NANOGEL-CONTAINING POLYMERS - The invention relates to a method for producing metal salt nanogel-containing aqueous dispersions, solid intermediate products and waterproof plastic products, thus allowing the simple production of novel products having homogeneously distributed agents, which exhibit, for example, an antimicrobial or barrier effect and/or have an absorbing capacity, such as with respect to oxygen, humidity, chemical, particularly gaseous compounds, or electromagnetic or radioactive radiation. | 07-15-2010 |
| 20110177021 | COMPOSITION FOR FORMING A TEMPORARY OBSTRUCTION AND METHOD OF FORMING THE SAME - The present invention relates to a method for forming a temporary obstruction of the intestine of a mammal, using a solidifiable composition, said composition being flow-able and solidifiable to form a solid plug at a desired site within the intestine, the structure of said plug being changeable in order to allow for the subsequent, at least partial removal of the obstruction. | 07-21-2011 |
| 20090317355 | ABUSE RESISTANT MELT EXTRUDED FORMULATION HAVING REDUCED ALCOHOL INTERACTION - The present invention relates to compositions for oral administration. The invention preferably comprises at least one abuse-resistant drug delivery composition for delivering a drug having potential for dose dumping in alcohol, related methods of preparing these dosage forms, and methods of treating a patient in need thereof comprising administering the inventive compositions to the patient. Most preferably, the dosage form includes verapamil. These formulations have reduced potential for abuse. In another formulation, preferably the abuse relevant drug is an opioid and the non-abuse relevant drug is acetaminophen or ibuprofen. More preferably, the opioid is hydrocodone, and the non-abuse relevant analgesic is acetaminophen. In certain preferred embodiments, the dosage forms are characterized by resistance to solvent extraction; tampering, crushing or grinding. Certain embodiments of the inventions provide dosage forms that provide an initial burst of release of drug followed by a prolonged period of controllable drug release. | 12-24-2009 |
| 20080267902 | BLOOD PRODUCTS WITH BINDING AGENT - The present invention provides a non-liquid biomaterial that may be used as a surgical sealant, a suture support, a blood flow controller, an adhesion reducing agent, an adhesion preventing agent, a tissue support, a tissue filler, a wound dressing or a combination thereof. The non-liquid biomaterial may comprise a blood derived material such as plasma, platelet poor plasma, platelet rich plasma or a material derived from blood containing tissue aspirate, such as bone marrow aspirate, a protein binding agent and a polymerizing agent. Methods for making and using the non-liquid biomaterial are also provided. | 10-30-2008 |
| 20110135593 | STERILIZING POLYMER AND METHOD OF PREPARATION THEREOF - The present invention provided a polymer and a method for preparing the polymer, wherein the polymer was a terpolymer having a molecular weight of more than 1000, and copolymerized by acrolein, acrylic acid, and low alkene-alkyl dibasic acid or low-alkene-alkyl polybasic acid. | 06-09-2011 |
| 20080226584 | ANTIMICROBIAL AND ANTISTATIC POLYMERS AND METHODS OF USING SUCH POLYMERS ON VARIOUS SUBSTRATES - The present invention relates to a substrate having one or more antimicrobial or antistatic properties. Such properties are imparted by applying a coating or film formed from a cationically-charged polymer composition. The polymer composition includes a noncationic ethylenically unsaturated monomer and an ethylenically unsaturated monomer capable of providing a cationic charge to the polymer composition. Optionally, the polymer composition includes a steric stabilization component incorporated into the cationically-charged polymer composition. The present invention also relates to a personal care product and polymeric material comprising a base polymer blended with the above cationically-charged polymer composition. | 09-18-2008 |
| 20090074708 | Inhibitors and Enhancers of Uridine Diphosphate-Glucuronosyltransferase 2B (UGT2B) - A UGT2B inhibitor capable of increasing the bio-availability of a drug, is a compound in a free base or a pharmaceutically acceptable salt form that is selected from the group consisting of: capillarisin, isorhamnetin, β-naphthoflavone, α-naphthoflavone, hesperetin, terpineol, (+)-limonene, β-myrcene, swertiamarin, eriodictyol, cineole, apigenin, baicalin, ursolic acid, isovitexin, lauryl alcohol, puerarin, trans-cinnamaldehyde, 3-phenylpropyl acetate, isoliquritigenin, paeoniflorin, gallic acid, genistein, glycyrrhizin, protocatechuic acid, ethyl myristate, umbelliferone, PEG (Polyethylene glycol) 400, PEG 2000, PEG 4000, Tween 20, Tween 60, Tween 80, BRIJ® 58, BRIJ® 76, Pluronic® F68, Pluronic® F127, and a combination thereof. A UGT2B enhancer capable of enhancing a clearance rate of morphine-like analgesic agents, is a compound in a free base or a pharmaceutically acceptable salt form that is selected from the group consisting of: nordihydroguaiaretic acid, wogonin, trans-cinnamic acid, baicalein, quercetin, daidzein, oleanolic acid, homoorientin, hesperetin, narigin, neohesperidin, (+)-epicatechin, hesperidin, liquiritin, eriodictyol, formononetin, quercitrin, genkwanin, kaempferol, isoquercitrin, (+)-catechin, naringenin, daidzin, (−)-epicatechin, luteolin-7-glucoside, ergosterol, rutin, luteolin, ethyl myristate, apigenin, 3-phenylpropyl acetate, umbelliferone, glycyrrhizin, protocatechuic acid, poncirin, isovitexin, 6-gingerol, cineole, genistein, trans-cinnamaldehyde, and a combination thereof. | 03-19-2009 |
| 20100209382 | Polyphenol Conjugates as RGD-Binding Compounds and Methods of Use - Provided herein are compositions and methods for preventing and treating diseases and risk factors associated with metabolic syndrome by targeting the RGD-binding site of selected intra- and extracellular proteins. Exemplary compositions include RGD-polyphenol conjugates via an ester linkage; polyphenol polymer conjugated to RGD analogs or mimetics; and RGD polymer conjugates linked to polyphenol. | 08-19-2010 |
| 20120003177 | CURCUMIN-CONTAINING POLYMERS AND WATER-SOLUBLE CURCUMIN DERIVATIVES AS PRODRUGS OF PRODRUG CARRIERS - Curcumin, a polyphenol extracted from the rhizome turmeric, has been polymerized to produce a polymer material having a backbone of one or more repeating structural units, at least one of which comprises a curcumin monomer residue. These curcumin-containing polymers have a wide range of pharmacological activities, including, among others antitumor, antioxidant, antiinflammatory, antithrombotic and antibacterial activities. Certain species of these polymers have exhibited remarkable antitumor activity. Water-soluble curcumin derivatives and their use as prodrugs and prodrug carriers are also disclosed. | 01-05-2012 |
| 20120027715 | POLYMER FILMS WITH EMBEDDED IODINATED RESIN AND METHODS OF MANUFACTURING SAME - The disclosure relates to polymer films containing iodinated resin, where such films have advantageous antibacterial and/or antitoxic properties. The films may be used, for example, in medical tape, wound dressings and bandages. In certain embodiments, the invention is also directed to methods of manufacturing such polymer films, where various manufacturing difficulties have been addressed and overcome. | 02-02-2012 |
| 20120082637 | Lacquer Composition Comprising a Monomer with a Polyalicyclic Structure Element - A transparent lacquer composition that can be used as a protective and gloss lacquer for surface coating is described. The lacquer composition can be a dental material and a method for preparing a lacquer composition is also described. Also described are novel polymerizable monomers comprising at least one polyalicyclic structure element and certain ethylenic structure elements that are particularly suitable for use in a lacquer composition. | 04-05-2012 |
| 20120282212 | AQUEOUS OLIGOMER/POLYMER EMULSION WITH CATIONIC FUNCTIONALITY - An aqueous emulsion comprising at least a covalently bound vinyl oligomer and vinyl polymer, wherein said vinyl oligomer comprises 5 to 85 mol % of vinyl monomers bearing quaternary ammonium ion functional groups or quaternisable amine functional groups and is obtained by a controlled radical polymerisation of at least one vinyl monomer via a reversible addition-fragmentation chain transfer mechanism in solution in the presence of a control agent and a source of free radicals; wherein said vinyl polymer is obtained by emulsion polymerisation of vinyl monomers in the presence of the vinyl oligomer; wherein the weight % ratio of vinyl oligomer to vinyl polymer is in the range of from 0.5:99.5 to 65:35. | 11-08-2012 |
| 424780320 | Heterocyclic monomer | 22 |
| 20110195042 | Compositions, Methods and Kits Useful for Treating a Respiratory Symptom - The present disclosure describes methods for enhancing an overall cooling sensation of an oral mucosa comprising administering a liquid composition comprising a thickening agent and/or a mucoadhesive polymer, a non-menthol coolant; and contacting the oral mucosa with the liquid composition. The disclosure also describes the liquid compositions. | 08-11-2011 |
| 20130039881 | COMBINATION FOR THE TREATMENT OF RADIATION- OR CHEMOTHERAPY-INDUCED MUCOSITIS - The present invention relates to the use of a combination of glycine, proline, and optionally a natural or synthetic film-forming polymer, and/or lysine and/or leucine, to prepare a composition for the treatment of mucositis induced by radiation or chemotherapy. | 02-14-2013 |
| 20130101547 | THERMORESPONSIVE COMPOSITIONS FOR DERMATOLOGICAL USE AND METHODS THEREOF - The present specification generally relates to compositions comprising a thermoresponsive polymer and methods of treating a soft tissue condition using such compositions. | 04-25-2013 |
| 20090047233 | Method for removing Phosphate and Polymer Used Therefore - Polymers and compositions utilizing such polymers are disclosed for treating hyperphosphatemia and other illnesses associated with elevated serum phosphate levels. Phosphate binding polymers, or a pharmaceutically acceptable salt of the polymers, comprise pendent groups extending from a backbone of the polymer. Each pendent group comprises at least two nitrogen-bearing functional groups which bind phosphate. Variations of such polymer and compositions are disclosed. | 02-19-2009 |
| 20120288469 | ANTIMICROBIAL SOLID AND METHODS OF MAKING AND USING SAME - A solid material adapted to kill bacteria in planktonic, spore and biofilm states is lethal toward a wide spectrum of gram positive and gram negative bacteria as well as other microbes. The solid material includes a significant amount of one or more surfactants entrained in a crosslinked polymeric network. | 11-15-2012 |
| 20090148396 | BIOCOMPATIBLE BIODEGRADABLE FUMAGILLIN ANALOG CONJUGATES - Fumagillin analog polymer conjugates, methods of making fumagillin analog polymer conjugates, compositions comprising a polymer conjugate of a fumagillin analog, and methods for treating cancer, or treating angiogenic diseases comprising administering to a subject in need thereof an effective amount of a polymer conjugate of a fumagillin analog, are described. Also described are novel fumagillin analogs, methods of making fumagillin analogs, compositions comprising at least one fumagillin analog, and methods for treating cancer, or treating angiogenic diseases comprising administering to a subject in need thereof an effective amount of a fumagillin analog. | 06-11-2009 |
| 20090104144 | Gypsum board with a fluorine-containing antifungal agent - A novel gypsum board having improved antifungal properties is disclosed. The board comprises a gypsum core, front and back paper facings, and a polymeric antifungal agent effective at inhibiting fungal growth. A preferred polymeric antifungal agent is polyDADMAC or polyTMMC. The novel gypsum board further comprises a non-polymeric antifungal agent comprising a fluorine-containing quaternary ammonium compound. Preferred non-polymeric ammonium compounds include Tetra-n-butylammonium fluoride and Tetraethylammonium fluoride. The polymeric antifungal agent can be present in the gypsum core and/or on one or both of the paper facings. The non-polymeric antifungal agent may be encapsulated in a material or ionically associated with the polymeric antifungal agent to allow releases of the non-polymeric antifungal agent over time and/or upon exposure to moisture. Methods for preparing the aforementioned novel gypsum board are also disclosed. | 04-23-2009 |
| 20080286225 | Antimicrobial and Antiviral Product - An antimicrobial and/or antiviral polymer is provided. The polymer is a modified polymer of a precursor polymer that comprises nitrogen atoms. The precursor polymer is modified into the antimicrobial and/or antiviral polymer of the present invention by substituting at least part of the nitrogen atoms with a (C | 11-20-2008 |
| 20100297057 | PESTICIDE COMPOSITIONS EXHIBITING ENHANCED ACTIVITY AND METHODS FOR PREPARING SAME - Pest controlling compositions exhibiting enhanced pesticidal activity levels and methods for preparing the same are disclosed. In one embodiment, a method includes providing a liquid composition that includes at least one pesticide and at least one co-ingredient that enhances pesticidal activity of the composition compared to a composition dissimilar only in not having the at least one co-ingredient. The at least one co-ingredient may include at least one metal oxide, a combination of at least one transition metal salt and at least one proteinaceous material or a combination of at least one proteinaceous material and at least one polymeric material. The method further includes spray drying the liquid composition to provide a solid composition. In one aspect of this embodiment, the solid composition provided by the spray drying exhibits enhanced pesticidal activity compared to the liquid composition. | 11-25-2010 |
| 20090074709 | METHODS, DEVICES AND SYSTEMS FOR BIOCIDAL SURFACE ACTIVITY - A method of applying a biocidal polymer to a surface including applying a solution of the biocidal polymer to the surface, wherein the biocidal polymer includes biocidal groups and the biocidal polymer is insoluble in water. The biocidal groups can be selected from the group consisting of quaternary salt groups or haloamino groups. | 03-19-2009 |
| 20080279809 | COATING MATERIAL FOR METAL SURFACES HAVING ANTIADHESIVE PROPERTIES - A composition curable by polymerization, as well as a process of applying the composition and metal substrates coated therewith, the composition comprising: a) at least one metal compound which reacts before and/or during the curing of the composition by polymerization, with at least one of components b), c) or, if present, d), so that the metal is bound in the cured composition, the metal being selected from silicon, titanium, zirconium, manganese, zinc, vanadium, molybdenum and tungsten; b) at least one monomer or oligomer which contains at least one carboxyl or ester group and at least one olefinic double bond and which has no polyether chain of at least five ethylene oxide and/or propylene oxide units; c) at least one compound which contains both a polyether chain of at least five ethylene oxide and/or propylene oxide units and at least one carboxyl or ester group having at least one polymerizable double bond; and optionally d) at least one initiator for free radical and/or cationic polymerization and/or e) a biocidal active. | 11-13-2008 |
| 20080226585 | Method for Treating Surfaces with Copolymers - The present invention relates to a method for treating at least a surface of a substrate containing labile hydrogen atoms to confer to it cytotoxic properties or cell-adhesion properties, characterized in that it comprises at least a step consisting of exposing, within a liquid medium, said substrate or a surface thereof with at least a copolymer, said copolymer containing at least a monomer unit of type A including at least a reactive site able to attach to said substrate or said surface by covalent bonds and at least a monomer unit of type B including at least one molecule able to confer antimicrobial, antiviricidal and/or antifungicidal or cell-adhesion properties to said substrate or said surface, said step being carried out in efficient conditions to promote the covalent grafting of said copolymer to said substrate or a surface thereof. | 09-18-2008 |
| 20100284959 | SEQUENCE SPECIFIC DOUBLE-STRANDED DNA/RNA BINDING COMPOUNDS AND USES THEREOF - The present invention provides specific double-stranded DNA/RNA binding compounds having a polymeric structure, which are in fact, triplex forming molecules capable of binding tightly and specifically to predetermined sequences in the major groove of double stranded nucleic acid molecules; as well as pharmaceutical compositions comprising thereof. The triplex forming molecules and the pharmaceutical compositions of the invention can be used for various therapeutic applications such as site-specific modulation of gene expression and targeting of DNA or RNA damage, as well as for diagnostic applications in vitro. | 11-11-2010 |
| 20100310498 | ACTIVE AGENTS AND THEIR OLIGOMERS AND POLYMERS - Conjugates comprising at least two active agents linked by a diglycolic acid or polyglycol diacid linker are disclosed. The invention also concerns oligomers and polymers of these conjugates and their use in therapeutic and industrial applications for localized, immediate or fast release delivery of an active agent, such as an anti-microbial, anti-infective, or antiseptic agent. | 12-09-2010 |
| 20110189120 | AEGYPTIN AND USES THEREOF - The present invention relates to the discovery of the Aegyptin gene and Aegyptin protein, a molecule that interacts with collagen and inhibits platelet adhesion, activation and aggregation. Novel biological tools, prophylactics, therapeutics, diagnostics, and methods of use of the foregoing are also disclosed. | 08-04-2011 |
| 20100040573 | CATIONIC POLYMERS AS THICKENERS FOR AQUEOUS AND ALCOHOLIC COMPOSITIONS - The present invention relates to a method for producing polymers by radically polymerizing a mixture comprising 99.99 to 10% by weight of at least one α,β-ethylenically unsaturated compound with at least one cationogenic and/or cationic group per molecule, 0 to less than 25% by weight of at least one monoethylenically unsaturated amide-group-containing compound different from a) and also 0.01 to 5% by weight of a crosslinker using at least two different water-insoluble initiators. | 02-18-2010 |
| 20120027716 | Povidone Iodine, A Novel Alternative Preservative For Ophthalmic Compositions - The invention includes a preserved ophthalmic preparation comprising povidone-iodine (PVP-I) at a concentration sufficient to preserve the ophthalmic preparation, and at least one member selected from the group consisting of a steroidal anti-inflammatory compound, a non-steroidal anti-inflammatory compound, an antibacterial compound, an anti-allergy compound, and an anti-glaucoma compound. The invention also includes adding PVP-I to an ophthalmic composition in order to preserve the composition, wherein the PVP-I is added at a concentration sufficient to preserve the composition. | 02-02-2012 |
| 20100247478 | METHOD FOR STABILIZING VERTEBRAL BODY ARCHITECTURE - A method for reducing the occurrence of new post-operative fractures in vertebrae of a patient's spine after a vertebroplasty procedure performed to stabilize a fracture in a vertebra of a patient comprising the steps of performing a vertebroplasty procedure to stabilize a fracture in a vertebra of the patient, wherein the vertebroplasty procedure comprises the step of injecting a material into the fractured vertebra, wherein the material is formed by mixing together a first paste and a second paste, wherein the first paste comprises at least one of a polymerizable monomer and a filler, and wherein the second paste comprises at least one of a polymerizable monomer and a filler. | 09-30-2010 |
| 20120076750 | FIBRIN BASED GLUE WITH FUNCTIONALIZED HYDROPHILIC POLYMER PROTEIN BINDING AGENT - The present invention provides a non-liquid biomaterial that may be used as a surgical sealant, a suture support, a blood flow controller, an adhesion reducing agent, an adhesion preventing agent, a tissue support, a tissue filler, a wound dressing or a combination thereof. The non-liquid biomaterial may comprise a blood derived material such as plasma, platelet poor plasma, platelet rich plasma or a material derived from blood containing tissue aspirate, such as bone marrow aspirate, a protein binding agent and a polymerizing agent. Methods for making and using the non-liquid biomaterial are also provided. | 03-29-2012 |
| 20100272672 | CROSSLINKED HYDROGELS - The present invention preferably provides for a method of forming and the resulting solid polymer gel composition comprising polyethylene imine and at least one hydrogen bonding polymer. The composition has a greater viscosity than either of the polyethylene imine or the hydrogen bonding polymer alone and is injectable immediately after mixing of the polyethylene imine and the at least one hydrogen bonding polymer. A method of tissue repair may include mixing about 9.25% (w/w) to about 13.65% (w/w) polyethylene imine and about 18.02% (w/w) to about 26.62% (w/w) polyvinyl alcohol to form an injectable composition; injecting the injectable composition into a cavity within a human body; and allowing the composition to solidify in situ. A kit may include a multi-barrel syringe at least one barrel is loaded with polyethylene imine and at least another barrel is loaded with at least one hydrogen bonding polymer. | 10-28-2010 |
| 20080317703 | Novel Composition for Xerostomia - An oral care composition is described for use in the treatment or alleviation of the symptoms of dry mouth comprising polyvinyl pyrrolidone (PVP) or a derivative thereof, an anionic mucoadhesive polymer and an orally acceptable carrier or excipient. | 12-25-2008 |
| 20090130051 | Flavonoid Compounds and Uses Thereof - Novel flavonoid compounds having anti-oxidant activity are described. The compounds and compositions have been shown to exhibit anti-oxidant properties and are particularly useful in the treatment of ischemia and reperfusion injuries. The invention also describes a method to chemically synthesize such flavonoid compounds and test their efficacy. Such compounds and corresponding pharmaceutically acceptable derivatives and/or salts have uses in the areas of pharmaceuticals, nutraceutical, and veterinary applications. | 05-21-2009 |
| 424780350 | Nitrogen or sulfur containing monomer | 24 |
| 20080267903 | Bioactive Polymers - Various polymers, including cationic polyamine polymers and dendrimeric polymers, are shown to possess anti-proliferative activity, and may therefore be useful for treatment of disorders characterised by undesirable cellular proliferation such as neoplasms and tumours, inflammatory disorders (including autoimmune disorders), psoriasis and atherosclerosis. The polymers may be used alone as active agents, or as delivery vehicles for other therapeutic agents, such as drug molecules or nucleic acids for gene therapy. In such cases, the polymers' own intrinsic anti-tumour activity may complement the activity of the agent to be delivered. | 10-30-2008 |
| 20090304623 | Once A Day Formulation for Phosphate Binders - A method for reducing serum phosphate in a subject in need thereof comprising administering once per day to said subject a phosphate binder, wherein the phosphate binder has a phosphate binding capacity of at least 52 mmole. | 12-10-2009 |
| 20120288470 | OPHTHALMIC SYSTEM WITH SYNERGISTIC PROPERTIES - Disclosed herein are ophthalmic cleaning systems and methods for their use, which comprise an ophthalmic solution and lens case, wherein the solution includes dual disinfectants and the lens case includes silver. When the lens case is combined with the solution according to the system of the present invention, it surprisingly exhibits synergistic activity which results in a faster antimicrobial activity. | 11-15-2012 |
| 20090257976 | SINGLE VIAL FORMULATION FOR MEDICAL GRADE CYANOACRYLATE - Alkyl cyanoacrylate compositions and methods for making those compositions, utilizing high purity monomeric starting materials, formed into more viscous oligomers, and combined with a plasticizer and inhibitor to provide a single-container, storage stable medical cyanoacrylate. | 10-15-2009 |
| 20100135950 | Iron(II)-Containing Treatments for Hyperphosphatemia - A pharmaceutical composition comprises a pharmaceutically acceptable ferrous iron compound; an amine polymer or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. Alternatively, a pharmaceutical composition comprises a pharmaceutically acceptable ferrous iron compound and pharmaceutically acceptable carrier, wherein the ferrous iron compound is selected from the group consisting of iron(II) acetate, iron(II) citrate, iron(II) ascorbate, iron(II) oxalate, iron(II) oxide, iron(II) carbonate, iron(II) carbonate saccharated, iron(II) formate, iron(II) sulfate, iron(II) chloride, iron(II) acetylacetonate and combinations thereof. A method of treating a subject with hyperphosphatemia comprises administering to the subject an effective amount of a pharmaceutical composition as described above. | 06-03-2010 |
| 20080260680 | Method of Attenuating Reactions to Skin Irritants - The present invention is directed to a method of inhibiting CDld activation by administering a composition containing a moiety that blocks CDld activation. Compositions of the invention are useful for the attenuation of CDld-restricted immune responses, including treatment of skin disorders due to hyperactive immune responses (e.g., contact hypersensitivity), for systemic administration to attenuate ongoing immune responses, and to provide hypoallergenic cosmetic products including pharmaceutical, cosmetic, and skin care compositions. Preferably, these compositions are in a form intended for topical administration. | 10-23-2008 |
| 20090117071 | Hydrophobically Modified Cationic Polymers And Their Use As Cleaning Aids - A cleaning composition for hard surfaces containing a polymeric compound comprising a main backbone derived from at least the following monomeric components: (I) 20 to 99.9% by weight of at least one cationic monomer according to formula (I) wherein R | 05-07-2009 |
| 20120244105 | Pharmaceutical Compositions Comprising Polymeric Binders with Non-Hydrolysable Covalent Bonds and Their Use in Treating Celiac Disease - A pharmaceutical composition comprising a polymeric binder including a high molecular weight synthetic polymer having a backbone constituted of non hydrolysable covalent bonds, said polymer being able to form electrostatic bonds at a pH lower than the isoelectric point of gluten and peptides derived from the degradation of gluten, and being able to bind to gluten or peptides derived from the degradation of gluten in the gastrointestinal tract, and a pharmaceutically acceptable carrier. Methods of using the polymeric binder for binding gluten or a peptide derived from the degradation of gluten, for decreasing the degradation of gluten into toxic peptides or for decreasing interaction of gluten or peptides derived from the degradation of gluten with the gastrointestinal mucosa. | 09-27-2012 |
| 20120148522 | Biocompatible Polyelectrolyte Complexes and Methods of Use - An article comprising a polyelectrolyte complex comprising an interpenetrating network of at least one predominantly positively charged polyelectrolyte polymer and at least one predominantly negatively charged polyelectrolyte polymer, the polyelectrolyte complex further comprising a plurality of closed-shell pores, the plurality of pores having at least one average transverse dimension between about 100 nanometer and about 1000 micrometers. | 06-14-2012 |
| 20110059040 | COMPOSITIONS AND METHODS FOR INHIBITING VIRAL AND BACTERIAL ACTIVITY - Described herein are methods of inhibiting the activity of a virus or a bacterium comprising contacting a virus or bacterium with a polymer functionalized with at least one boronic acid moiety. Also described are methods of treatment using such functionalized polymers. | 03-10-2011 |
| 20120201779 | ANTIHISTAMINE AND ANTIHISTAMINE-LIKE NASAL APPLICATION, PRODUCTS - A method of and product for reducing the undesirable effects of allergic rhinitis by applying a formulation to a person's nasal region or nostrils. The formulation creates a barrier that prevents airborne allergens from contacting nasal mucous membranes, and at the same time, electrostatically repels or attracts and captures the particulate allergens, and changes their shapes so as to mitigate the effects of allergic rhinitis. The formulation may be made more effective by the addition of an anti-histamine compound. | 08-09-2012 |
| 20100330027 | Cyanoacrylate Initiator System - The present invention is directed to curable compositions that comprise a non-porous substrate, one or more cyanoacrylate polymerization initiators and a prepolymer composition comprising at least one liquid cyanoacrylate monomer or mixture of such monomers (solid or liquid) and/or cyanoacrylate oligomers. The non-porous substrate is a collection of individual particulates that are not bound, bonded or fixed to one another. At least one initiator is deposited on the surface of the individual particulates to form a plurality of initiator carriers. The prepolymer composition receives the plurality of initiator carriers to begin a controlled and consistent polymerization or curing of the liquid cyanoacrylate monomer in order to produce a biocompatible adhesive composition for use on living tissue. The present invention also provides for methods of making and using and devices for such a curable compositions, particularly in treating living tissue by applying to living tissue a biocompatible adhesive composition. | 12-30-2010 |
| 20110318298 | VIRAL INFECTION THERAPEUTIC DRUG CONTAINING POLYALKYLENEIMINE - Methods for administering a polyalkyleneimine to treat or prevent a viral infection, inactivate a virus, inhibit viral adsorption to a cell, and inhibit viral invasion of a cell are presented. | 12-29-2011 |
| 20080311071 | Film Forming Compositon - The present application relates to a film forming composition for application to mammalian skin, which composition comprises at least one polyurethane based polymer together with at least one acrylate based polymer. The film forming composition provides effective skin coating with good adhesion to the skin, and may be used as a skin protector or a wound dressing. | 12-18-2008 |
| 20120251483 | Infarction Treatment Compositions and Methods - Provided are methods of treating cardiac infarction by using an injectable material to influence cardiac structure and remodeling after infarction. Also provided are kits that comprise an injectable material to influence cardiac structure. | 10-04-2012 |
| 20100092421 | Process for the Preparation of Sevelamer Hydrochloride and Formulation Thereof - Disclosed herein is an improved process for preparation of Sevelamer hydrochloride having phosphate binding capacity of 4.7 to 6.4 mmol/g. Further, the invention discloses Sevelamer hydrochloride compositions and a novel process for preparation of said compositions comprising high shear non-aqueous granulation. | 04-15-2010 |
| 20100092420 | Preservative Systems Comprising Cationic Surfactants - Preservative systems on the basis of cationic surfactants are known i n the art, a typical example of such cationic surfactants is the ethyl ester of the lauramide of arginine monohydrochloride (LAE) (2). Besides the chloride form the corresponding bromide and sulphate salts are known. It was found that other salts of the cationic surfactants display excellent properties, such as the salts of lactic acid, glutamic acid and acetic acid. It was further found that the combination of the cationic surfactants with at least one salt of an organic or inorganic acid displayed an excellent preservative action. A further preservative system with favourable properties was the combination of the cationic surfactants with at least one ester compound, amide or enzyme inhibitor. Also the combination of the cationic surfactant with a further cationic molecule such as ethyl arginate, glucosamine or chitosan led to an effective preservative system. A further effective preservative system turned out to be the cationic surfactant in encapsulated form. | 04-15-2010 |
| 20120121532 | PROCESS FOR MAKING DRY AND STABLE HEMOSTATIC COMPOSITIONS - Described is a process for making a dry and stable hemostatic composition, said process comprising | 05-17-2012 |
| 20120134952 | Antiviral Method - This invention provides a method of inactivating non-enveloped virus particles. The method includes the step of contacting the virus with a virucidally-enhanced alcoholic composition that includes an alcohol, and an enhancer selected from the group consisting of cationic oligomers and polymers, proton donors, chaotropic agents, and mixtures thereof. | 05-31-2012 |
| 20120171155 | Durable Antimicrobial Composition - The present invention relates to compositions having durable antimicrobial activity. The compositions include a carbonate/bicarbonate salt of a quaternary ammonium cation, an organic acid, hydrogen peroxide and a polymer. The polymer is selected from cationic amine polymer-epichlorohydrin adduct, cationic amine polymer-epichlorohydrin resin, poly(methacrylamidopropyltrimethylammonium)chloride, poly(bis(2-chloroethyl)ether-alt-1,3-bis(dimethylamino)propyl)urea, poly(diallyldimethylammonium)chloride, poly(t-butyl acrylate co-ethyl acrylate co-methacrylic acid), polyethylene oxide, polyquaternium-16, polyquaternium-22, polyquaternium-67 and mixtures thereof. | 07-05-2012 |
| 20110002875 | METHOD FOR TREATING AMYLOIDOSIS - Therapeutic compounds and methods for inhibiting amyloid deposition in a subject, whatever its clinical setting, are described. Amyloid deposition is inhibited by the administration to a subject of an effective amount of a therapeutic compound comprising an anionic group and a carrier molecule, or a pharmaceutically acceptable salt thereof, such that an interaction between an amyloidogenic protein and a basement membrane constituent is inhibited. Preferred anionic groups are sulfonates and sulfates. Preferred carrier molecules include carbohydrates, polymers, peptides, peptide derivatives, aliphatic groups, alicyclic groups, heterocyclic groups, aromatic groups and combinations thereof. | 01-06-2011 |
| 20120321585 | Crosslinked Hydrogels and Related Method of Preparation - The present invention provides a method of manufacturing a hydrogel comprising the step of crosslinking a biopolymer using a carbodiimide crosslinker of Formula I wherein at least one of R | 12-20-2012 |
| 20130011364 | MOLECULARLY IMPRINTED POLYMERS FOR ELIMINATING METABOLITES - The present invention relates to polymers imprinted by retention solutes, use of same as well as compositions containing same. | 01-10-2013 |
| 20130022570 | CROSSLINKED POLYVINYLAMINE, POLYALLYLAMINE, AND POLYETHYLENEIMINE FOR USE AS BILE ACID SEQUESTRANTS - The present invention provides a crosslinked amine and amide polymers effective for binding and removing bile salts from the gastrointestinal tract. These bile acid binding polymers or pharmaceutical compositions thereof can be administered to subjects to treat various conditions, including hypercholesteremia, diabetes, pruritis, irritable bowel syndrome-diarrhea (IBS-D), bile acid malabsorption, and the like. | 01-24-2013 |
