Entries |
Document | Title | Date |
20080206185 | Personal Care Composition Comprising a Silicone Elastomer - The present invention is directed to a personal care composition comprising: | 08-28-2008 |
20080305069 | Cosmetic Use of Tensing Agents to Improve the Thickness of the Skin and/or the Radiance of the Complexion - The invention relates in particular to the cosmetic use of a composition containing, in a physiologically acceptable medium, an effective amount of at least one mosaic-effect tensing agent for improving the thickness of the skin and/or promoting the radiance of the complexion. The invention also relates to the cosmetic use, in a composition containing a physiologically acceptable medium, of an effective amount of at least one mosaic-effect tensing agent as an agent intended to improve the firmness and/or elasticity and/or tonicity of the skin. The invention likewise relates to a cosmetic method of treatment of dull and/or poorly defined complexion that comprises the topical application of a composition comprising at least one mosaic-effect tensing agent to people who have a dull and/or poorly defined complexion. Mosaic-effect agents of this kind are selected in particular from (i) mineral tensing agents and (ii) tensing polymers. | 12-11-2008 |
20080317702 | METHOD FOR TREATING MICROORGANISMS AND/OR INFECTIOUS AGENTS - This invention relates to a method comprising contacting a microorganism and/or an infectious agent with an effective amount of a polymer composition to reduce or eliminate the reproductivity, metabolism, growth and/or pathogenicity of the microorganism and/or infectious agent, the polymer composition comprising water, a water-soluble film forming polymer, a chelating agent, and a surfactant. | 12-25-2008 |
20090074706 | MULTI-ARM POLYMERIC CONJUGATES OF 7-ETHYL-10-HYDROXYCAMPTOTHECIN FOR TREATMENT OF BREAST, COLORECTAL, PANCREATIC, OVARIAN AND LUNG CANCERS - A four arm-polyethylene glycol-7-ethyl-10-hydroxycamptothecin conjugate, such as, | 03-19-2009 |
20090136442 | ERYTHROPOIETIN RECEPTOR PEPTIDE FORMULATIONS AND USES - The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention also relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production. Pharmaceutical compositions, which comprise the peptide compounds of the invention, and dosages are also provided. | 05-28-2009 |
20090246166 | Pearl Like Polyvinyl Alcohol Particles, Production Process Thereof and Temporary Vascular Embolic Agent - The embodiments provide a temporary vascular embolic agent temporarily blocking the blood vessel in vivo, having appropriate dissolution speed suitable for use in the blood vessel in which blood flow is fast and being more superior in the passing property of a catheter and the controllability of embolization time than conventional one. The embolization of the blood vessel led to cardiac muscle in which blood flow speed is fast is enabled by the temporary vascular embolic agent of the present invention using the pearl like polyvinyl alcohol (PVA) particles having 0.1 to 2% by mol of a 1,2-diol configuration unit and having a saponification degree of at least 99% by mol. | 10-01-2009 |
20090246167 | STIMULI-RESPONSIVE SYSTEMS FOR CONTROLLED DRUG DELIVERY - A method of delivering a therapeutic agent by providing a cross-linked polymer encapsulating the therapeutic agent to a site in a patient. The degradation rate of the cross-linked polymer is correlated with a local concentration of an indicator, and the therapeutic agent is released as the cross-linked polymer degrades. | 10-01-2009 |
20100047203 | Use of Block Copolymers Based on Vinyllactams and Vinyl Acetate as Solubilizers - Use of polyvinyllactam-polyvinyl acetate block copolymers as solubilizers for active ingredients that are sparingly soluble in water. | 02-25-2010 |
20100055068 | GRAFTED POLYMERS AND USES THEREOF - The invention features grafted polymer systems for use in medical devices and/or for the delivery of active agents. The grafted polymers include at least one transport moiety, a linear backbone segment, and a pendant segment. | 03-04-2010 |
20100119471 | MYCOPLASMA HYOPNEUMONIAE BACTERIN VACCINE - The invention provides an improved | 05-13-2010 |
20100166695 | Multivalent Heterobifunctional Polymers And Methods Of Their Use - Designed herein are multivalent heterobifunctional polymers for binding to a biological target exhibiting biological activity and to an effector template which can affect the biological activity of the biological target or detect the presence of the biological target. The polymers comprise a plurality of pre-arranged heterobifunctional ligands connected thereto, and each heterobifunctional ligand comprises a first functionality capable of binding to the biological target, and a second functionality capable of binding to the effector template. The heterobifunctional ligands are pre-arranged on the polymer so as to form a ternary complex between the polymer, the biological target and the effector template. The polymers, methods and compositions described herein provide an approach for the design and production of new therapeutic agents as well as agents useful in a variety of non-therapeutic applications. | 07-01-2010 |
20100178269 | Compositions and Methods for the Treatment of Heart Failure - The invention provides a therapeutic composition comprising an aqueous buffer, and a therapeutic agent that improves the functioning of a diseased heart by decreasing left ventricular end-diastolic pressure and simultaneously increasing left ventricular ejection without affecting the blood pressure or heart rate. | 07-15-2010 |
20100215613 | PVA Particle for Temporary Embolic Material and Production Process Thereof, and Temporary Embolic Material - A temporary embolic material for blood vessel which can embolize a blood vessel in a living body and is used for the temporary embolization of the blood stream. More specifically, disclosed is an embolus-forming material comprising a specific PVA particle which can be used for the closure of the inner lumen of a blood vessel by the PVA particle to embolize the blood stream, which can ultimately be absorbed in the living body, which can be excreted out of the body and which does not remain in the body. A pearl-like polyvinyl alcohol particle for use as a temporary embolic material, the particle having a saponification degree of 90 mol % or higher and an average particle diameter of 70 to 1000 μm; and a temporary embolic material comprising the particle mixed or dissolved therein. | 08-26-2010 |
20100266526 | Combination therapy for treating hypercholesterolemia - The invention relates to methods for treating hypercholesterolemia and atherosclerosis, and reducing serum cholesterol in a mammal. The methods of the invention comprise administering to a mammal a first amount of a bile acid sequestrant compound which is an unsubstituted polydiallylamine polymer and a second amount of a cholesterol-lowering agent. The first and second amounts together comprise a therapeutically effective amount. | 10-21-2010 |
20100330026 | ORGANIC POLYMERIC PHOTON UP-CONVERSION NANOPARTICLES FOR BIOLOGICAL APPLICATIONS - The present invention relates to organic polymeric photon up-conversion nanoparticles for biological applications, such as labeling and/or detection of cells, biological (macro-) molecules or other analytes, as well as for sensing temperature, pressure, oxygen and other substances that influence the up-conversion process. It further relates to organic photon up-conversion nanoparticles for singlet oxygen generation and the treatment of diseases, such as cancer. | 12-30-2010 |
20110097299 | SWELLABLE AND DEGRADABLE MICROSPHERES - Swellable and degradable microspheres are described. The microspheres are prepared by a process that is reliable and high yielding, and makes use of a low temperature azo initiator, a small molecule chlorinated solvent as the organic phase, and a heat treatment step, and is carried out in absence of a crosslinking agent. The microsphere preparation made using the process is particularly useful as a degradable embolic material. | 04-28-2011 |
20110142788 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE ORGANIC STRUCTURING AGENT, AT LEAST ONE ABSORBENT MIXTURE AND AT LEAST ONE SURFACTANT FOR APPLICATION TO KERATIN MATERIALS - Provided herein is an anhydrous cosmetic composition comprising at least one organic structuring agent, at least one modified starch, at least one wood meal, at least one surfactant, and at least one anhydrous liquid phase. Also provided is a method for cleansing and/or conditioning keratin materials, comprising applying at least one of the anhydrous cosmetic compositions to the keratin materials. | 06-16-2011 |
20110206634 | COMPOSITE MATERIAL FOR TISSUE REPAIR - The present disclosure provides a biocompatible composite and method for its use in repairing tissue defects, including defects in cartilage. The biocompatible composite includes a fibrous polymeric component and a polymerizable agent, which is capable of forming the biocompatible composite in situ at the site of a tissue defect. In embodiments, the repair site at which the biocompatible composite is to be applied may be treated with a priming agent, permitting polymerization of the polymerizable agent to the tissue located at the repair site. | 08-25-2011 |
20120100097 | CELLULOSE SUPPORT CONTAINING D-MANNOSE DERIVATIVES - Cellulose support containing mannose derivatives able to fix type 1 piliated bacteria, application to disinfecting wipes especially. Support intended to bind type 1 piliated bacteria comprising cellulose fibers and/or regenerated cellulose fibers onto which mannose derivative is fixed characterized in that the mannose derivative is present in the form of copolymer obtained by copolymerization of: —a monomer derivative of alkenyl α-D-mannopyranoside modified with a function capable of reacting with an acrylamid monomer, —a cationic monomer —an acrylamid monomer. | 04-26-2012 |
20120121530 | Vasoprotective and cardioprotective antidiabetic therapy - The present invention relates to certain DPP-4 inhibitors for treating and/or preventing oxidative stress, vascular stress and/or endothelial dysfunction as well as to the use of such DPP-4 inhibitors in treatment and/or prevention of diabetic or non-diabetic patients, including patient groups at risk of cardiovascular and/or renal disease. | 05-17-2012 |
20120121531 | BIOCOMPOSITE FOR ARTIFICIAL TISSUE DESIGN - The present invention concerns a biocomposite useful in artificial tissue replacement, methods for its production, and methods of use. The biocomposite can be implanted into humans or animals as an artificial tissue for treatment of a tissue defect. The biocomposite can be formed or manipulated into a desired shape for implantation. | 05-17-2012 |
20120258069 | RGD-BINDING COMPOUNDS AND METHODS OF USE - Provided herein are compositions and methods for preventing and treating diseases and risk factors associated with metabolic syndrome by targeting the RGD-binding site of selected intra- and extracellular proteins. Exemplary compositions include RGD-polyphenol conjugates via an ester linkage; polyphenol polymer conjugated to RGD analogs or mimetics; and RGD polymer conjugates linked to polyphenol. | 10-11-2012 |
20120301424 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTICS DELIVERY - The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein. | 11-29-2012 |
20120308508 | MICROGEL COMPOSITIONS - This invention relates to microgel compositions, and in particular, to gel compositions formed by binding a plurality of individual microgel particles together. The present invention also relates to processes for the preparation of these compositions and their use for particular applications, especially medical applications such as the repair of damaged, degenerated or inappropriately formed load-bearing tissue (such as, for example, intervertebral discs). | 12-06-2012 |
20120315240 | VISCOELASTIC ANTIMICROBIAL COMPOSITIONS AND METHODS - Viscoelastic compositions capable of preventing microbial proliferation and capable of capturing microbrial membrane and cell wall decomposition products are provided, the compositions including reaction products of drying oils and semi-drying oils and methacrylate polymers. The compositions are capable of absorption or incorporation of lipopolysaccharide and protein membrane materials and endotoxins. | 12-13-2012 |
20130034516 | USE OF THE MODIFIED POLYSACCHARIDES FOR HEPARIN NEUTRALIZATION - The subject of the invention is the use of cationically modified polysaccharides, except for chitosan, for direct neutralization of heparin in blood and physiological fluids in a mammal. Cationic modification of the polysaccharides is achieved using compound containing cationic ammonium groups and/or the polysaccharides are grafted with a polymer containing amine and/or ammonium groups. | 02-07-2013 |
20130071348 | NANOPARTICLES WITH COVALENTLY BOUND SURFACTANT FOR DRUG DELIVERY - The present invention concerns nanoparticles, compositions comprising the nanoparticles, methods for their production, and methods of using the nanoparticles for the delivery of biologically active agents (e.g., antibiotics or other drugs) to human or non-human subjects. In one embodiment, the nanoparticle is a “surfactant-free” nanoparticle in which the surfactant moiety is covalently attached to the backbone of the polymer. | 03-21-2013 |
20130121955 | METHODS AND COMPOSITIONS FOR STABILIZING THE MYOCARDIUM - The present invention provides materials and methods that can serve as a prosthetic and/or, for tissue engineer applications, as a supporting matrix in the stabilization of the myocardium. | 05-16-2013 |
20130171091 | Nanocell Drug Delivery System - Nanocells allow the sequential delivery of two different therapeutic agents with different modes of action or different pharmacokinetics. A nanocell is formed by encapsulating a nanocore with a first agent inside a lipid vesicle containing a second agent. The agent in the outer lipid compartment is released first and may exert its effect before the agent in the nanocore is released. The nanocell delivery system may be formulated in pharmaceutical composition for delivery to patients suffering from diseases such as cancer, inflammatory diseases such as asthma, autoimmune diseases such as rheumatoid arthritis, infectious diseases, and neurological diseases such as epilepsy. In treating cancer, a traditional antineoplastic agent is contained in the outer lipid vesicle of the nanocell, and an antiangiogenic agent is loaded into the nanocore. This arrangement allows the antineoplastic agent to be released first and delivered to the tumor before the tumor's blood supply is cut off by the antianiogenic agent. | 07-04-2013 |
20140242024 | Hydrogel Implants with Varying Degrees of Crosslinking - The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions. | 08-28-2014 |
20140255333 | THERMAL RESPONSIVE POLYMER SILOXANES, COMPOSITIONS, AND METHOD AND APPLICATIONS RELATED THERETO - The invention relates to materials comprising siloxanes, preferably the materials have thermal-responsive properties. In some embodiments, the invention relates to silsesquioxane groups functionalized with polymers. In another embodiment, silsequioxane-polymer conjugates comprise polylactone segments. The silsequioxane-polymer conjugates may be crosslinked together to form a material, and these materials may be functionalized with bioactive compounds so that the materials have desirable biocompatibility or bioactivity when used in medical devices. In further embodiments, the invention relates to composite materials that contain a polymer matrix and aggregates, and in some embodiments, methods of making, and methods of using these materials. Preferably, the aggregates are calcium phosphate aggregates. Preferably, the material is resistant to fracture. In further embodiments, the materials are used in surgical procedures of bone replacement. In further embodiments, the materials contain polyhedral silsesquioxanes and/or biodegradable segments. | 09-11-2014 |
20140314703 | IMMUNOGENIC COMPLEXES OF POLYANIONIC CARBOMERS AND ENV POLYPEPTIDES AND METHODS OF MANUFACTURE AND USE THEREOF - The present invention relates to immunogenic complexes formed between polyanionic carbomers and Env polypeptides. Uses of the immunogenic complexes in applications including inducing an immune response and immunization generally are described. Methods of forming and manufacture of the immunogenic complexes are also described. The present invention also relates to immunogenic compositions including low viscosity, polyanionic carbomers and Env polypeptides. Uses of such immunogenic compositions in applications including inducing an immune response and immunization generally are described. Methods of manufacture of such immunogenic compositions are also described. | 10-23-2014 |
20150064131 | PHARMACEUTICAL COMPOSITIONS COMPRISING POLYMERIC BINDERS WITH NON-HYDROLYSABLE COVALENT BONDS AND THEIR USE IN TREATING CELIAC DISEASE - A pharmaceutical composition comprising a polymeric binder including a high molecular weight synthetic polymer having a backbone constituted of non hydrolysable covalent bonds, said polymer being able to form electrostatic bonds at a pH lower than the isoelectric point of gluten and peptides derived from the degradation of gluten, and being able to bind to gluten or peptides derived from the degradation of gluten in the gastrointestinal tract, and a pharmaceutically acceptable carrier. Methods of using the polymeric binder for binding gluten or a peptide derived from the degradation of gluten, for decreasing the degradation of gluten into toxic peptides or for decreasing interaction of gluten or peptides derived from the degradation of gluten with the gastrointestinal mucosa. | 03-05-2015 |
20150071870 | Superabsorbent Materials Comprising Peroxide - This invention pertains to a polymeric composition and an antimicrobial composition, each comprising a superabsorbent polymer (SAP), such as used in diapers and sanitary napkins, and peroxide. The superabsorbent material can be made by the process of treating a preformed SAP, such as a crosslinked polyacrylate salt, with a treatment solution comprising hydrogen peroxide dissolved in water, followed by drying. The resulting superabsorbent material has strong antimicrobial activity. Optionally, the treatment solution may also contain a metal salt, including those of zinc, zirconium, and magnesium. | 03-12-2015 |
20150305330 | ADVANCED VISCOELASTIC ANTIMICROBIAL COMPOSITIONS AND METHODS - Viscoelastic compositions capable of preventing microbial proliferation and capable of capturing microbial membrane and cell wall decomposition products are provided. The compositions comprise thermal reaction products of blends of fatty acids derived and isolated from drying and semi-drying oils such as linseed, safflower, and tung oil, with a polymer component such as for example poly (isobutyl methacrylate). These compositions are capable of capturing microbes and controlling their proliferation at a material on which the compositions are deposited, and further capable of absorption or incorporation of lipopolysaccharide and protein membrane materials and endotoxins. | 10-29-2015 |
20160158273 | BATHWATER AND SOAK ADDITIVE - The present disclosure generally relates to a bathwater additive which renders the bathwater viscous and slippery. | 06-09-2016 |
20220133956 | METHODS AND POLYMER COMPOSITIONS FOR TREATING RETINAL DETACHMENT AND OTHER OCULAR DISORDERS - The invention provides methods and polymer compositions for treating retinal detachment and other ocular disorders, where the methods employ polymer compositions that can form a hydrogel in the eye of a subject. The hydrogel is formed by reaction of (i) a nucleo-functional polymer that is a biocompatible polymer containing a plurality of thio-functional groups —R1-SH wherein R1 is an ester-containing linker, such as a thiolated poly(vinyl alcohol) polymer and (ii) an electro-functional polymer that is a biocompatible polymer containing at least one thiol-reactive group, such as a poly(ethylene glycol) polymer containing alpha-beta unsaturated ester groups. | 05-05-2022 |