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Measuring optical property by using ultraviolet, infrared, or visible light

Subclass of:

422 - Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing

422050000 - ANALYZER, STRUCTURED INDICATOR, OR MANIPULATIVE LABORATORY DEVICE

422680100 - Means for analyzing liquid or solid sample

Patent class list (only not empty are listed)

Deeper subclasses:

Class / Patent application numberDescriptionNumber of patent applications / Date published
422820080 Fluorescence 42
422820090 Absorbance or transmittance 16
422820110 Waveguides 10
422820060 Optode or optrode 4
20110236264MICROFLUIDIC DEVICE FOR SEPARATING AND SORTING PARTICLES IN A FLUID MEDIUM - A microfluidic device for separating emulsion solution into separate particles by passing the emulsion solution through a passive filter. The separated particles can then be sorted into separate chambers through active filtering.09-29-2011
20100178208OPTICAL SENSOR ARRAY SYSTEM FOR PARALLEL PROCESSING OF CHEMICAL AND BIOCHEMICAL INFORMATION - Total analysis systems and methods for simultaneously monitoring a suite of biological and/or chemical species in water and/or other process systems are disclosed. The system provides a sample-volume controlled sensor array comprising a fluid delivery device and a plurality of optical sensor elements for determining the presence and total concentrations of multiple analytes in the process system simultaneously. Image identification algorithms are provided for identifying the analytes based on image intensity, color pattern, positional arrangement, and the like. The methods incorporate multivariate optimization algorithms to analyze multiple sensor responses. This produces analytical results that are typically difficult to obtain without full system or variable compensation. The improved array response may then be utilized to measure, monitor, and control the concentration of analytes in the chemical or biological sample or water system.07-15-2010
20110064617ELECTRO-OPTICAL SENSING DEVICE WITH REFERENCE CHANNEL - An electro-optical sensing device for detecting the presence and concentration of an analyte in a liquid or gaseous medium includes a pair of indicator elements positioned to receive radiation from a radiation source and transmit radiation to a pair of photosensitive elements. The indicator elements each contain indicator molecules having an optical characteristic responsive to the presence of an analyte; however, one of the indicator elements is covered by an analyte-impermeable chamber that renders the indicator element insensitive to the presence of the analyte in the medium outside the chamber so that it can be used as a reference to cancel environmental and systemic variables that affect both indicator elements. The chamber preferably holds an analyte-containing fluid in contact with the reference indicator element so that the indicator elements operate under nominally identical conditions. The indicator element used to measure the analyte in the external medium is preferably also covered, but in a manner that provides direct contact between the analyte and the indicator element.03-17-2011
20080199360Method and composition for a platinum embedded sol gel optical chemical sensor with improved sensitivity and chemical stability - A process for manufacturing a material, (medium or matrix) to hold or encapsulate sensing molecules with enhanced sensitivity to oxygen gas and dissolved oxygen by mixing a platinum compound with sol-gel monomers and then coating the tip of an optical fiber is disclosed. The sol-gel polymerizes, trapping the platinum compound in an oxygen permeable glass like solid. The high quenching efficiency of the Pt compound upon oxygen exposure makes the sensor extremely sensitive to oxygen partial pressure variations and also resistant to exposure to hydrocarbons.08-21-2008
Entries
DocumentTitleDate
20080260585REACTION CONTAINER AND ANALYZING APPARATUS - A reaction container holds a liquid agitated by sound waves. The reaction container includes two openings which serve as an introduction/discharge port of the liquid, and a holding member which has the two openings, holds the liquid between the two openings, and includes a sound wave generator arranged on one of a side surface and a portion close to the side surface for emitting sound waves to a portion between the two openings to agitate the liquid.10-23-2008
20120244039OESTRUS DETECTOR - An oestrus detector 09-27-2012
20120244038Scanning Tunneling Microscope Assembly, Reactor, and System - An embodiment of a scanning tunneling microscope (STM) reactor includes a pressure vessel, an STM assembly, and three spring coupling objects. The pressure vessel includes a sealable port, an interior, and an exterior. An embodiment of an STM system includes a vacuum chamber, an STM reactor, and three springs. The three springs couple the STM reactor to the vacuum chamber and are operable to suspend the scanning tunneling microscope reactor within the interior of the vacuum chamber during operation of the STM reactor. An embodiment of an STM assembly includes a coarse displacement arrangement, a piezoelectric fine displacement scanning tube coupled to the coarse displacement arrangement, and a receiver. The piezoelectric fine displacement scanning tube is coupled to the coarse displacement arrangement. The receiver is coupled to the piezoelectric scanning tube and is operable to receive a tip holder, and the tip holder is operable to receive a tip.09-27-2012
20130078150GEL PARTICLE MEASUREMENT DEVICE - To measure a starting point of production of gel particles with high sensitivity in measurement of a target substance in a sample through a gelation reaction while minimizing light attenuation in a solvent in which a phenomenon occurs, provided is a gel particle measurement device including: a sample cuvet (03-28-2013
20120183442Body fluid testing component for simultaneous analyte detection - An analyte testing device is provided for use with a mobile processing device having a camera with a lens, a processor for processing an image captured by the lens. The analyte testing device comprises a casing and a test strip positioner. The test strip positioner positions an analyte containing test strip adjacent to the camera lens to permit the camera to capture an image of the analyte containing test strip. A light source is disposed within the casing. The light source is positioned within the casing to illuminate the analyte containing test strip to facilitate the capture of the image of the test strip. Software is contained within the mobile processing device for performing a quantitative analysis of at least one analyte from the captured image, and providing an output of the results of the quantitative analysis.07-19-2012
20120183441Assay Preparation Plates, Fluid Assay Preparation and Analysis Systems, and Methods for Preparing and Analyzing Assays - A fluid assay preparation and analysis system is provided which includes a pipette disposed above an assay plate receiving area, a magnet disposed below the assay plate receiving area in approximate alignment with the pipette, and an actuator configured to move the magnet proximate the assay plate receiving area. A method for preparing and analyzing an assay includes injecting a sample into a sample well of an assay preparation plate and inserting the assay preparation plate into a fluid assay analysis system. The method further includes mixing the sample with one or more reagents in an assay plate receiving area of the system and subsequently aspirating the prepared assay into an examination chamber of the system.07-19-2012
20130039810BIOREACTOR VESSEL HAVING AN OPTICAL FOAM SENSOR - A bioreactor vessel has an optical foam sensor (02-14-2013
20090098022MULTI-CHANNEL DEVICE AND METHOD FOR MEASURING OPTICAL PROPERTIES OF A LIQUID - A multi-channel device includes up to three channels for optical testing of liquid samples. The liquid sample(s) may include surface water, drinking water, processed water or the like. The multi-channel device may include a turbidity channel and a color channel that measure turbidity and color, respectively, of a liquid sample using spectrographic analysis. The multi-channel device may also include a colorimetric channel that measures the concentration of various analytes in a liquid sample, such as free chlorine, total chlorine, copper and phosphate.04-16-2009
20100092339MICROFLUIDIC SYSTEM, SAMPLE ANALYSIS DEVICE, AND TARGET SUBSTANCE DETECTION/MEASUREMENT METHOD - A microfluidic system includes a plate-shaped microfluidic chip having a flow path, a liquid introduction tube for supplying liquid to the flow path, the liquid introduction tube having an end communicating with an end of the flow path and its other end that can be soaked in the liquid that is to be supplied to the flow path, and a liquid discharge head communicating with the other end of the flow path for discharging liquid that has passed through the flow path.04-15-2010
20090092518STIRRER AND ANALYZER - A stirrer is for stirring by sound waves a liquid held by a vessel. The stirrer includes a sound wave generator that generates sound waves to be applied to the liquid; and a controller that controls a temperature of the liquid, increased by the sound waves emitted by the sound wave generator, at a predetermined temperature or less.04-09-2009
20090047180Fluid handling device - It is to make a separate component for preventing disengagement of a strip plate incorporated into a frame unnecessary, to allow attachment and detachment of the strip plate to and from the frame by a single operation, and to allow the strip plate and the frame to be smoothly attached and detached without the strip plate disengaging from the frame during a manual operation such as transportation and without specimens and the like within wells spilling when an external force is applied to attach and detach the strip plate to and from the frame.02-19-2009
20120114527FLOW MODULE - The present invention relates to a channel plate comprising a number of rows of units, at least one inlet and at least one outlet, at least one turning box, wherein turning boxes being connections between two adjacent rows of units in the channel plate, that fluid may flow from one row to the other in the created room. The present invention relates further to flow sections and flow module.05-10-2012
20090010806Apparatus for Photo Reduction of Contaminants in Blood and Blood Products with Calibration Means - An apparatus for irradiating blood or blood products, preferably with ultra violet or visible light, to reduce contaminants in the blood or blood products. A removable radiometer having light integrating chambers detects the light intensity, allowing the radiation characteristics of the apparatus to be calibrated. A control circuit uses the measurements to control the delivery of an effective dose of illumination to blood or blood products in a bag or container. One or more light integrating optical chambers in the radiometer allow a single light sensor to sense light across an entire field. Thermistors in the irradiating apparatus or the radiometer or both sense the temperature of photo sensors. The control circuit compensates for temperature-dependant variations in the output of the photo sensors.01-08-2009
20120237401STRUCTURES FOR CONTROLLING LIGHT INTERACTION WITH MICROFLUIDIC DEVICES - Systems and methods for improved measurement of absorbance/transmission through fluidic systems are described. Specifically, in one set of embodiments, optical elements are fabricated on one side of a transparent fluidic device opposite a series of fluidic channels. The optical elements may guide incident light passing through the device such that most of the light is dispersed away from specific areas of the device, such as intervening portions between the fluidic channels. By decreasing the amount of light incident upon these intervening portions, the amount of noise in the detection signal can be decreased when using certain optical detection systems.09-20-2012
20110027129Method for formation of reagent layer in analysis apparatus, method for manufacture of anlalysis apparatus, and analysis apparatus - The present invention relates to a method for forming a reagent layer in an analytical tool including a first step of holding a reagent-containing liquid onto a substrate, and a second step of drying the reagent-containing liquid. A liquid containing a tetraborate as a drying accelerator is used as the reagent-containing liquid. A content of a tetraborate in the reagent-containing liquid is, for example 1 g or more based on 100 mL of the reagent-containing liquid. The tetraborate is, for example, tetrasodium borate or tetrapotassium borate.02-03-2011
20090068065Simple, Field Portable Colorimetric Detection Device For Organic Peroxides and Hydrogen Peroxide - A simple and effective system for the calorimetric determination of organic peroxides and hydrogen peroxide. A peroxide pen utilizing a swipe material attached to a polyethylene tube contains two crushable vials. The two crushable vials contain a calorimetric reagent separated into dry ingredients and liquid ingredients. After swiping a suspected substance or surface the vials are broken, the reagent is mixed thoroughly and the reagent is allowed to wick into the swipe material. The presence of organic peroxides or hydrogen peroxide is confirmed by a deep blue color.03-12-2009
20100166612BIOLOGICAL ANALYSIS SYSTEMS, DEVICES AND METHODS - A device for performing biological sample reactions comprising a plurality of flow cells each with at least one port for receiving reaction fluids delivered to a chamber of each flow cell and a manifold configured to receive the plurality of flow cells, wherein the manifold is configured to receive at least one reaction fluid, and wherein each flow cell is configured with a sample holder wherein the sample holder contains biological sample.07-01-2010
20120189497SYSTEM AND METHOD FOR REPOSITIONING A DIAGNOSTIC TEST STRIP AFTER INOCULATION - A system for analyzing the concentration of an analyte in a fluid sample comprises a test strip and a meter. The test strip is capable of being inoculated by the fluid sample. The test strip includes a test element, which contains at least one reagent adapted to cause a reaction when brought into contact with the analyte. The meter includes a read-head, a repositioning device, and a display. The read-head is capable of producing a signal indicative of the reaction between the analyte and the at least one reagent. The display is capable of displaying the analyte concentration. The repositioning device is adapted to move the test strip from a loading position to a testing position. The testing position positions the test element proximate to the read-head.07-26-2012
20090129984CHEMICAL EXPOSURE INDICATION DEVICE - A chemical exposure indication device is disclosed. The device is removably attachable to a structure and includes a substrate having a first surface and a second surface and an indicating layer overlying the first substrate surface. The indicating layer includes a coating material that is chemically reactive with a pre-determined chemical compound that is known to degrade the structure. When the coating material is exposed to that corrosive compound in a pre-determined level associated with degradation of a metallic structure, the coating material provides a visual indication of the presence of the corrosive compound.05-21-2009
20090129983Device For the Growth of Macromolecular Crystals and Drug Screening - The invention is a device for counter-diffusion applications comprising a removable cartridge having a plurality of capillary tubes that may be disposed between first and second members. The first member may be moveable into at least a first and second position. The second member may be moveable into a sealing position wherein the distal ends of the capillary tubes contact a sealant material. In the first position, the proximal ends of the capillary tubes may contact a macromolecular solution, which may cause the macromolecular solution to diffuse into the interior space of the capillary tube. In the second position, the proximal ends of the capillary tubes may be inserted into a corresponding reservoir well having a precipitating solution. The macromolecular solution and the precipitating solution may then counter diffuse against each other in each capillary tube. The removable cartridge may then be removed and replaced with a new removable cartridge.05-21-2009
20090148346SUBSTRATE WITH BINDING FUNCTIONAL GROUP - A structural member having a binding functional group on a substrate for binding a capturing molecule capable of capturing a target substance, characterized in that the substrate binds to one end of a polymer which includes at the other end those to which the binding functional group is bound and those to which a suppressing functional group for suppressing adsorption of biological molecules to the structural member and that the suppressing functional group is also bound to a side chain of the polymer.06-11-2009
20100098590CLEANING DEVICE, METHOD FOR DETECTING SUCTION NOZZLE CLOGGING, AND AUTOMATIC ANALYZER - A cleaning device includes a discharge nozzle that discharges cleaning liquid; a suction nozzle that sucks the cleaning liquid or reaction liquid in the cleaning tank or the reaction vessel; a discard vessel connected to the suction nozzle via a pipe to discard the cleaning liquid or the reaction liquid; a detecting unit that detects whether an electrostatic capacity at least between the suction nozzle and an electrode provided in the pipe exceeds a threshold value; a determination unit that determines that the suction nozzle is clogged when a totalizing time, for which the electrostatic capacity exceeds the threshold value during a preset clogging determination time, is longer than a totalizing time, for which the electrostatic capacity exceeds the threshold value during a preset normal determination time; and a control unit that stops the discharge nozzle from discharging the cleaning liquid to the reaction vessel when the suction nozzle is clogged.04-22-2010
20100098589ERROR SPECIFYING METHOD AND ANALYZER - An error specifying method of specifying an error of an analyzer. The method specifies an error related to removal of a high-concentration reagent. The method includes a low-concentration reagent measuring step of performing an analysis process, which causes a composition to emit light, on a low-concentration reagent and measuring an amount of light emitted in order to acquire performance of the low-concentration reagent; a high-concentration reagent measuring step of performing the analysis process on the high-concentration reagent and measuring an amount of light emitted in order to acquire performance of the high-concentration reagent; and a reagent evaluating step of evaluating the performance of the low-concentration reagent and the performance of the high-concentration reagent based on the measurement results in the low-concentration reagent measuring step and the high-concentration reagent measuring step.04-22-2010
20120107179MULTILAYERED OPTICAL SENSING PATCH AND RETAINING PLUG THEREFOR - A multilayered optical sensing patch, for the measurement of conditions, such as pH, oxygen level, etc, within containers, is provided. The multilayered optical sensing patch of the present invention is comprised of a heat sealable polymer substrate layer, and a polymeric sensing membrane later attached thereto. The polymer sensing membrane layer is formed of a porous polymer support membrane, and an optical sensing composition (comprising a reactive indicator) covalently bonded thereto. The heat sealable polymer substrate layer is capable of being securely bonded to the inner layer of bioreactor bags, as well as the porous polymer support substrate layer. Further, the porous polymer support membrane layer provides a firm supporting structure for the polymeric sensing layer, thereby protecting the optical sensing composition disposed therein from degradation/damage.05-03-2012
20090263285METHOD AND DEVICE FOR LAMINAR FLOW ON A SENSING SURFACE - Methods and devices are provided for controlling a fluid flow over a sensing surface within a flow cell. The methods employ laminar flow techniques to position a fluid flow over one or more discrete sensing areas on the sensing surface of the flow cell. Such methods permit selective sensitization of the discrete sensing areas, and provide selective contact of the discrete sensing areas with a sample fluid flow. Immobilization of a ligand upon the discrete sensing area, followed by selective contact with an analyte contained within the sample fluid flow, allows analysis by a wide variety of techniques. Sensitized sensing surfaces, and sensor devices and systems are also provided.10-22-2009
20090263284METHOD AND DEVICE FOR LAMINAR FLOW ON A SENSING SURFACE - Methods and devices are provided for controlling a fluid flow over a sensing surface within a flow cell. The methods employ laminar flow techniques to position a fluid flow over one or more discrete sensing areas on the sensing surface of the flow cell. Such methods permit selective sensitization of the discrete sensing areas, and provide selective contact of the discrete sensing areas with a sample fluid flow. Immobilization of a ligand upon the discrete sensing area, followed by selective contact with an analyte contained within the sample fluid flow, allows analysis by a wide variety of techniques. Sensitized sensing surfaces, and sensor devices and systems are also provided.10-22-2009
20090263283MEASUREMENT CELL - A measurement cell 10-22-2009
20100061894APPARATUS FOR MEASURING IMMUNOCHROMATO TEST PIECE - A measuring apparatus 03-11-2010
20080240996METHOD OF DETECTING ANALYTES IN A MICROFLUIDIC SAMPLE AND A SYSTEM FOR PERFORMING THE SAME - An automated assay system includes a platform and a rotatable coupon removably positioned within or on the platform. The rotatable coupon includes a plurality of discrete tracks, each of the plurality of discrete tracks configured to contain microfluidic volumes. At least one magnet is operatively disposed on the platform, the rotatable coupon, or combinations thereof, and the at least one magnet is configured to generate a magnetic field at a predetermined area of the rotatable coupon. A motor is operatively connected to the rotatable coupon.10-02-2008
20080274016Biosensor and method of manufacturing biosensor - Aspects of the invention can be an inexpensive biosensor capable of measuring a number of samples in a short time, and suitable for only one-time use (expendable). The biosensor according to the invention can include a light transmissive substrate, a probe fixing region provided on one face of the light transmissive substrate, a light emitting element provided on the other face of the substrate that irradiates the probe fixing region from the back side thereof, and a light receiving element provided on the other face of the substrate that detects the light intensity of the reflected light from the back side of the probe fixing region. Thereby, a biosensor formed in one substrate can be obtained.11-06-2008
20090169432AUTOMATIC ANALYZER AND DISPENSING METHOD THEREOF - Provided are an automatic analyzer which moves a dispensing apparatus having a dispensing probe, or a vessel by a driving mechanism to dispense plural liquids into the vessel via the dispensing probe, and measures and analyzes optical characteristic of a reaction liquid in which each of the dispensed liquids is reacted, and a dispensing method thereof. The automatic analyzer includes a drive controlling unit which controls the driving mechanism so that the liquid surface of the liquid and a distal end of the dispensing probe are moved relatively to each other in a vertical direction, and, when the liquids including precipitated substance are to be dispensed, the dispensing probe sucks in the liquids from plural different positions along the vertical direction.07-02-2009
20080292503DETECTION DEVICE AND METHOD - A detection device and method for detecting the presence of an agent in a fluid. The device includes a membrane having first and second sides. The membrane allows a stimulus, e.g. ultraviolet light, to dissolve in response to presence of the agent. A source is positioned on a first side of the membrane. The source sources the stimulus toward the membrane. A detection structure is disposed on the second side of the membrane for detecting the stimulus. The detection structure generates an output voltage in response to the intensity of the stimulus detected. As the membrane dissolves, the intensity of the stimulus detected changes.11-27-2008
20080253931Diagnostic test device - A diagnostic test device comprises means for sampling a liquid biological sample and means for reacting the sample with at least one reagent to provide one or more visible indicia. The device also comprises an optical detector for detecting the presence of the one or more indicia. The device also comprises means for causing at least part of the optical detector to move over the one or more indicia.10-16-2008
20090297402ANALYZING INSTRUMENT, TEMPERATURE CONTROL METHOD FOR LIQUID IN ANALYZING INSTRUMENT, AND ANALYZING APPARATUS - This invention relates to a technique for adjusting the temperature of a liquid held on an analyzing instrument (12-03-2009
20090297401SENSOR KIT AND A SYSTEM FOR DETECTING AN ANALYTE IN A TEST ENVIRONMENT - A sensor kit for detecting an analyte. The sensor kit includes x indicator substances having a specific spectral response to the analyte, whereby 1≧x≦200. The sensor kit includes a substrate, which is to be illuminated on a first side and includes at least one indicator substance region arranged adjacent to a second side. Each indicator substance region is arranged for carrying one indicator substance and the substrate includes at least one indicator substance region for each indicator substance. A filter element is integrated with the substrate. The filter element includes at least one of each of n different filters, whereby 2≦n≦100. The filter element is arranged such that light firstly passes there through and thereafter through the indicator substance region(s). At least one of each of at least two different filters provides at least one indicator substance region with light when the substrate is illuminated.12-03-2009
20080240995REACTION VESSEL AND ANALYZER - An analyzer is for stirring a liquid held in a vessel by a sound wave and measuring optical characteristics of the liquid which has been stirred, to analyze the liquid. The analyzer includes a dispensing unit for dispensing the liquid to a dispensing holding unit formed in the vessel; and a light measuring unit for measuring optical characteristics of the liquid held in a light measuring holding unit to which the liquid which has been stirred is conveyed. A position of the light measuring unit in the vessel is different from a position of the dispensing holding unit.10-02-2008
20100196206DIAGNOSIS DEVICE USING IMAGE SENSOR AND METHOD OF MANUFACTURING THE SAME - A diagnosis device using an image sensor and a method of manufacturing the same are provided. The diagnosis device using the image sensor includes: a substrate in which an image sensor including a plurality of optical sensors is formed; an insulation layer formed on the substrate; and a plurality of wells formed in the insulation layer in correspondence with the plurality of optical sensors, the plurality of wells into which reference samples for biochemical reactions with a target sample are inserted.08-05-2010
20100150782DISPENSING NOZZLE AND AUTOMATIC ANALYZER - A dispensing nozzle includes a holding tube portion that holds a fluid as a dispensing target; and a discharge end face that is formed at a tip of the holding tube portion and that sucks in and discharges the fluid through an opening formed thereon. The discharge end face has a greater contact angle with the fluid than an inner face of the holding tube portion.06-17-2010
20100183479MULTILAYER PROCESSING DEVICES AND METHODS - Sample processing devices that include transmissive layers and control layers to reduce or eliminate cross-talk between process chambers in the processing device are disclosed. The transmissive layers may transmit significant portions of signal light and/or interrogation light while the control layers block significant portions of signal light and/or interrogation light. Methods of manufacturing processing devices that include transmissive layers and control layers are also disclosed. The methods may involve continuous forming processes including co-extrusion of materials to form the transmissive layer and control layer in a processing device, followed by formation of the process chambers in the control layer. Alternatively, the methods may involve extrusion of materials for the control layer, followed by formation of process chambers in the control layer.07-22-2010
20090047181DETERMINING FLUID CHEMISTRY OF FORMATION FLUID BY DOWNHOLE REAGENT INJECTION SPECTRAL ANALYSIS - A method for analyzing formation fluid in earth formation surrounding a borehole includes storing analytical reagent in a reagent container in a fluids analyzer in a formation tester and moving the formation tester, including the reagent, downhole. Reagent from the reagent container is injected into formation fluid in the flow-line to make a mixture of formation fluid and reagent. The mixture is moved through a spectral analyzer cell in the fluids analyzer to produce a time-series of optical density measurements at a plurality of wavelengths. A characteristic of formation fluid is determined by spectral analysis of the time-series of optical density measurements.02-19-2009
20100189603SUB-MICRON SURFACE PLASMON RESONANCE SENSOR SYSTEMS - A sensor for detecting the presence of a target analyte, ligand or molecule in a test fluid, comprising a light transmissive substrate on which an array of surface plasmon resonant (SPR) elements is mounted is described. A multi-channel sensor for detecting the presence of several targets with a single microchip sensor is described. A multi-channel sensor including collections of SPR elements which are commonly functionalized to one of several targets is also described. The detectors sense changes in the resonant response of the SPR elements indicative of binding with the targets.07-29-2010
20090016933CARRIER, PROCESS FOR PRODUCING SAME, BIOREACTOR, AND CHIP FOR SURFACE PLASMON RESONANCE ANALYSIS - A carrier comprises a base plate, a polymeric film, which has been bound on a surface of the base plate, and a ligand, which has been bound with the polymeric film. The ligand has been bound with the polymeric film at a density falling within the range of 1.0×1001-15-2009
20100254857CLEANING DEVICE AND AUTOMATIC ANALYZER - A cleaning device that cleans a liquid storage part of a vessel for storing liquid. The cleaning device includes: a cleaning liquid discharge nozzle that discharges cleaning liquid to the liquid storage part; a first overflow suction nozzle of which tip is positioned above the tip of the cleaning liquid discharge nozzle, that sucks the liquid containing the cleaning liquid from the liquid storage part; a second overflow suction nozzle of which tip is positioned above the tip of the first overflow suction nozzle, that sucks the liquid containing the cleaning liquid from the liquid storage part; and a clog detecting unit that detects clog in one of the first and second overflow suction nozzles.10-07-2010
20120141330AUTOMATIC ANALYZER - To be adapted to various types of latex reagents for detecting scattered light and thereby measuring agglutination reactions with high sensitivity while sufficiently ensuring integration time. To be adapted to various types of latex particles of different particle sizes, a plurality of light receivers are arranged in a plane perpendicular to the direction of cell movement by rotation of a cell disk. To ensure sufficient integration time, the angle between the optical axis of the irradiation light and each of a plurality of optical axes of scattered light viewed from above the cell is made equal to or less than 17.7° including a mounting error.06-07-2012
20120141329MICROFLUIDIC APPARATUS WITH INTEGRATED POROUS-SUBSTRATE/SENSOR FOR REAL-TIME (BIO) CHEMICAL MOLECULE DETECTION - Microfluidic apparatus including integrated porous substrate/sensors that may be used for detecting targeted biological and chemical molecules and compounds. In one aspect, upper and lower microfluidic channels are defined in respective halves of a substrate, which are sandwiched around a porous membrane upon assembly. In other aspect, the upper and lower channels are formed such that a portion of the lower channel passes beneath a portion of the upper channel to form a cross-channel area, wherein the membrane is disposed between the two channels. In various embodiments, one or more porous membranes are disposed proximate to corresponding cross-channel areas defined by one or more upper and lower channels. The porous membrane may also have sensing characteristics, such that it produces a change in an optical and/or electronic characteristic. Accordingly, the apparatus may further include instrumentation or detection equipment to measure the changes, such as optic-based detectors and electronic instrumentation.06-07-2012
20100129260GELATION MEASURING APPARATUS AND SAMPLE CELL - It is an object of the present invention to allow rapid and accurate measurement of the concentration of substances such as endotoxins, β-D glucans and the like that is measured by gelation reactions. In a gelation-reaction measuring apparatus for measuring a target substance in a sample via a gelation reaction, a sample cell for housing a sample containing the target substance to be measured and a solution containing a reagent that gelates is irradiated with irradiation light from a light emitting diode 05-27-2010
20120195799PROCESS ANALYZER - A process analyzer for detection of an analyte in a liquid under analysis includes a base module and an exchangeable cartridge module. The exchangeable cartridge module comprises a sample taking device comprising a membrane configured to obtain a sample from the liquid under analysis. A first pump mechanism is configured to pump the sample away from the sample taking device. A second pump mechanism is configured to introduce a reagent into the sample. A measuring section is configured to perform a quantitative detection of the analyte in the sample. A degassing device is arranged downstream of the first pump mechanism and the second pump mechanism. The degassing device is configured to degas the sample.08-02-2012
20090074621STIRRER AND ANALYZER - A stirrer is for stirring a liquid held in a vessel by sound waves. The stirrer includes a sound wave generator that generates the sound waves to be applied to the liquid; and a controller that controls drive conditions for the sound wave generator in accordance with changes with time of flow arising in the liquid by the sound waves. An analyzer is for stirring and reacting different liquids to measure an optical property of a reaction liquid using the stirrer, and thus to analyze the reaction liquid.03-19-2009
20080311005APPARATUS FOR FOCUSING AND DETECTING PARTICLES IN SAMPLE AND METHOD OF MANUFACTURING THE SAME - An apparatus for focusing a particle in a sheath flow, the apparatus comprising: a sheath fluid inlet for injecting a sheath fluid; a first flow channel for conveying a fluid, wherein the first flow channel extends from the sheath fluid inlet to the fluid outlet and is formed such that a channel extending from the sheath fluid inlet is divided into two subchannels that extend further and are then merged into one channel; and a second flow channel that extends from the sample fluid inlet to the sample fluid outlet, wherein the second flow channel is in fluid communication with the first flow channel at the merged channel region through the sample fluid outlet so as to introduce a particle in a sample into a sheath fluid conveyed through the first flow channel.12-18-2008
20130189159METHOD OF MODIFYING THE PROPERTIES OF A SURFACE - The present invention relates to a method, comprising: coating a surface with a mussel adhesive protein such that a first layer comprising the MAP is achieved on the first surface, and providing a second layer comprising a first plurality of particles on at least a portion of said first layer comprising said MAP. It also relates to a device comprising a substrate having a first surface; a first layer comprising said MAP, said first layer being arranged on said first surface, and a second layer comprising a first plurality of particles attached to at least a portion of said MAP of said first layer. The present invention is based on the realization that a MAP can advantageously be used to immobilize particles on a substrate, for example in a layer-by-layer assembly. Thereby, providing a highly functionalized surface.07-25-2013
20090022630MEASUREMENT SYSTEM WITH DISTRIBUTED FUNCTIONS - An analysis system is provided which comprises an integrated analysis device and a test strip magazine, for determining an analyte in a body fluid, wherein the analysis system comprises a first group comprising reusable components and a second group of components comprising a plurality of disposable articles. The second group includes non-electronic and electronic components, with critical interfaces configured between two or more such components, wherein non-electronic components can be disconnected from electronic components at a disconnection point. In one embodiment, critical interfaces are produced and tested during production of the analysis system.01-22-2009
20090110603Method For Detecting And Compensating An Underdosage Of Test Strips - The invention concerns a method for detecting an underdosage of an analytical test element and optionally for compensating the underdosage. The invention also concerns an analytical system and a test element which are suitable for detecting an underdosage.04-30-2009
20100303672DETERMINATION OF EXPLOSIVES INCLUDNIG RDX - The present invention provides sensors and methods for determination of an analyte. The analytes may be determined by monitoring, for example, a change in an optical signal of an emissive material upon exposure to an analyte. In some embodiments, the analyte and the emissive material may interact via a chemical reaction, or other chemical, biochemical or biological interaction (e.g., recognition), to form a new emissive species. In some cases, the present invention may be used for the detection of analytes such as explosives (e.g., RDX, PETN). Methods of the present invention may be advantageous in that the high sensitivity of luminescence (e.g., fluorescence) spectroscopy can allow for the reliable detection of small changes in luminescence intensity.12-02-2010
20100310424ORGANIC MATERIALS ABLE TO DETECT ANALYTES - The present invention generally relates to polymers with lasing characteristics that allow the polymers to be useful in detecting analytes. In one aspect, the polymer, upon an interaction with an analyte, may exhibit a change in a lasing characteristic that can be determined in some fashion. For example, interaction of an analyte with the polymer may affect the ability of the polymer to reach an excited state that allows stimulated emission of photons to occur, which may be determined, thereby determining the analyte. In another aspect, the polymer, upon interaction with an analyte, may exhibit a change in stimulated emission that is at least 10 times greater with respect to a change in the spontaneous emission of the polymer upon interaction with the analyte. The polymer may be a conjugated polymer in some cases. In one set of embodiments, the polymer includes one or more hydrocarbon side chains, which may be parallel to the polymer backbone in some instances. In another set of embodiments, the polymer may include one or more pendant aromatic rings. In yet another set of embodiments, the polymer may be substantially encapsulated in a hydrocarbon. In still another set of embodiments, the polymer may be substantially resistant to photobleaching. In certain aspects, the polymer may be useful in the detection of explosive agents, such as 2,4,6-trinitrotoluene (TNT) and 2,4-dinitrotoluene (DNT).12-09-2010
20110002813ANALYSIS METHOD, ANALYSIS DEVICE AND PRODUCTION METHOD THEREFOR - The present invention relates to a technique for analyzing the concentration of a specific component in a sample liquid, such as a method for analyzing a sample. The analyzing method includes a first detection step for irradiating light from a light source (01-06-2011
20090068064APPARATUS AND METHOD FOR CONDUCTING ASSAYS - A multi-well assay plate structure (03-12-2009
20110008213OPTIMIZED DETECTOR READOUT FOR BIOSENSOR - The present invention provides a biosensor system comprising a light source, a cartridge adapted to be illuminated by said light source, a light detector adapted for detecting a signal originating from the cartridge, an illumination control means adapted to vary the illumination of the cartridge between at least two different states, a means for generating a first oscillation with a first frequency, and a means for generating a second oscillation with a second frequency, wherein the frame rate of the light detector is triggered by the first oscillation and the illumination control means is triggered by the second oscillation.01-13-2011
20090214388METHOD FOR MANUFACTURING THE SCALE, SCALE, AND ENCODER-EQUIPPED APPARATUS - [Object] To provide a method for manufacturing a scale having an improved abrasion resistance, the scale, and an encoder having the same.08-27-2009
20100178207Method of optical detection of binding of a material component to a sensor substance due to a biological, chemical or physical interaction and apparatus for its embodiment (variants) - Apparatus for detecting biological or chemical components in liquid or gas is based on measuring changes of the sensor layer thickness due to binding reactions. A plate or a gap with two surfaces of a solid optical material is used as the sensor layer. The surfaces are located at a distance of more than 10 μm, which allows pumping liquids through the gap at moderate pressure drops and investigating large biological objects (e.g., cells), or employment of affordable plates that are rigid enough without any substrate. The indicated thickness of the plate or the gap permits using of the superluminescent diodes as light sources, because it allows recording within their narrow spectrum a sufficient number of interference maxima and minima for precise registration of molecular binding reactions, which lead to much higher sensitivity of the apparatus as compared with apparatus based on thin-film sensor layers.07-15-2010
20090035182AUTOMATIC ANALYZER - An object of the present invention is to provide an automatic analyzer which measures blank values for each vessel to reduce analysis time.02-05-2009
20110176966DEVICE AND METHOD FOR PRESSURE-DRIVEN PLUG TRANSPORT - The present invention provides microfabricated substrates and methods of conducting reactions within these substrates. The reactions occur in plugs transported in the flow of a carrier-fluid.07-21-2011
20100129261Spectral sensor for surface-enhanced raman scattering - The spectral sensor for surface-enhanced Raman scattering (SERS) of the present invention is prepared with a single-crystal noble metal nanowire which has a high quality, a high purity and an excellent shape. Thus, the sensor can be used for in-situ detection. Further, since a sensor site for reacting with irradiated laser beam can have a controlled structure, shape and a controllable hot spot, reliability and reproducibility are excellent and sensitivity of the sensor can be improved. In addition, with the optimization of a mechanical structure of a single noble metal single-crystal nanowire and a polarization direction of laser beam, sensitivity, selectivity and signal intensity become high. Furthermore, the spectral sensor for surface-enhanced Raman scattering of the present invention can be advantageously used not only as a sensor for detecting chemicals but also as a biosensor and a sensor for diagnosis of disease.05-27-2010
20110250093METHOD FOR PRODUCING A MAGAZINE BY INJECTION MOLDING, AND A MAGAZINE FOR AN ANALYSIS DEVICE - Method for the injection-molding production of a magazine having a plurality of chambers, separated by partition walls, including an outer wall formed by an outer wall of the magazine. The method uses a casting mold having an outer wall channel corresponding to the outer wall of the magazine, and partition wall channels corresponding to the partition walls, and a gate opening. A plurality of partition wall channels extend from the gate opening to the outer wall channel. The method comprises injecting a plastic compound into the gate opening. The plastic compound flows from the gate point to the partition wall channels into the outer wall channel. The plastic compound streams have a differing flow speed in alternating partition wall channels so a joint line, which is aligned with a partition wall channel, forms on the outer side of the outer wall channel.10-13-2011
20110076199DEVICE FOR THE PHOTOMETRIC EXAMINATION OF SAMPLES - A device for the photometric examination of samples has a sample-holder apparatus for at least two sample vessels, and a measuring apparatus and a moveable apparatus. The sample-holder apparatus is designed to be stationary, and the measuring apparatus is arranged on the moveable apparatus such that it can be displaced by means of the moveable apparatus.03-31-2011
20100310422OPTICAL BIOSENSOR - The present invention relates to an optical biosensor comprising a porous matrix. In the specific case, reference is made to anodized porous alumina, on the surface of which the biological component specific for the analyte in question is immobilized, and to an optical-signal detector connected to said matrix. The present patent further relates to a biosensor having the porous matrix and the optical detector integrated in a single structure, in particular to biosensors with porous matrix other than porous alumina, for example porous silicon.12-09-2010
20100310423FRUSTRATED TOTAL INTERNAL REFLECTION BIOSENSOR CARTRIDGE - The present invention provides a biosensor cartridge (12-09-2010
20080247911Measurement of Concentrations and Binding Energetics - Free-standing microfluidic channels are used to both transport and analyze molecules of interest. In a biochemical context, such molecules may be polypeptides, nucleic acids, or other biomolecules. The free-standing channels provide a real-time readout of concentration without the need for labeling with reporter molecules. The channels can also measure enthalpy values and equilibrium constants by detecting heat released from or absorbed by the sample.10-09-2008
20080247910Device for Testing a Fluid10-09-2008
20090324448CASSETTE AND MEASURING APPARATUS - An object of the invention is to provide a cassette and a measuring apparatus that can filter a sample for the optical measurement of an optically active substance and clean a sample flow channel by using a simple configuration. More specifically, the invention is directed to a cassette which includes a filter for filtering out a measurement interfering component from a sample, a container containing the filter, a cleaning liquid or cleaning agent for cleaning a sample flow channel, and a storage tank for storing the cleaning liquid or cleaning agent, and to a measuring apparatus having such a cassette.12-31-2009
20110165025STOPPED-FLOW CHIP - A chip for performing and measuring chemical reactions, interactions (bonds), and/or conformational changes, especially fast chemical reactions and processes. The chip includes a base plate, which is made of a polymer material that is transparent at least in the measuring zone, and having. fluid ducts parallel to the plane of the base plate and includes at least two reagent feeders leading into a mixer structure that has a number of inlets corresponding to the number of reagent feeders and an outlet leading into a mixing section, the outlet of the mixing section leads into a measuring section, the outlet of the measuring section is connected to a discharge section, the discharge section leads out of the base plate or into a reservoir that is arranged on the chip, and pressure conduits lead into the reagent feeders at a distance from the mixer structure.07-07-2011
20110256026MICRO-FLUIDIC DEVICE AND SAMPLE TESTING APPARATUS USING THE SAME - A microfluidic device having a delay structure and a sample testing apparatus including the microfluidic device are provided. The microfluidic device includes: a reaction chamber which contains a reagent capable of reacting with a sample; a distribution channel through which the sample is provided to the reaction chamber; an inlet channel through which the at least one reaction chamber is connected with the distribution channel; and a delay structure which is located between the at least one reaction chamber and the distribution channel, and delays movement of contents of the reaction chamber to the distribution channel.10-20-2011
20110033341TEST ELEMENT ANALYSIS SYSTEM - A test element analysis system for the analytical investigation of a liquid sample, comprising a test element including a carrier film having at least one flat side and a test field secured to the flat side and an evaluation instrument including a test element holder for positioning a test element in a measuring position, a measuring device for measuring the optically measurable change in the detection zone, and a housing within the measuring device is positioned. The test element is positioned in the measuring position in such a manner that a first partial section of the test element is located inside the housing and a second partial section is located outside of the housing to be easily accessible.02-10-2011
20100329933Grating-based sensor combining label-free binding detection and fluorescence amplification and readout system for sensor - A grating-based sensor is disclosed that has a grating structure constructed and designed for both evanescent resonance (ER) fluorescence detection and label-free detection applications. Some embodiments are disclosed which are optimized for ER detection in an air mode, in which the sample is dry. Other embodiments are optimized for ER detection in liquid mode, in which the sample is suspended in liquid medium such as water. One and two-dimensional gratings are also disclosed, including gratings characterized by unit cells with central posts, central holes, and two-level, two-dimensional gratings. A readout system for such sensors is also disclosed. One embodiment includes a first light source optimized for collecting label-free detection data, a second light source optimized for collecting ER fluorescence amplification data, and at least one detector. In one embodiment, the detector is in the form of an imaging system and includes a CCD camera for collecting both ER and label-free data. In other embodiments, the at least one detector takes the form of a spectrometer for collection of label-free data and a photomultiplier for collecting ER data. In other embodiments, a single light source such as a tunable laser or broad band light source is used.12-30-2010
20110052447Detection System for Detecting and Measuring Metal Ions in an Aqueous Medium - A detection system for detecting and measuring a metal ion in an aqueous medium includes a substrate that provides mechanical stability and is sized and shaped to intercept an optical beam (for example, a beam in the ultraviolet, visible or infraredregion). A reactive material is attached to the substrate, for example attached to the surface of the substrate or to a film that coats the substrate. The reactive material is capable of reacting with the metal ion and changing its optical spectrum upon reacting. For example, in one embodiment the reactive material includes a chelator that bonds to the metal ion to form a chelate complex. The detection system also includes an optical spectrometer producing the optical beam that passes through the reactive material to a detector of the spectrometer. For example, the spectrometer may be a Fourier transform, dispersive or filter based spectrometer. The changing of the optical spectrum of the reactive material allows the spectrometer to detect and measure the metal ion.03-03-2011
20100322825Microfluidic molecular-flow fractionator and bioreactor with integrated active/passive diffusion barrier - A microfluidic device and method is disclosed for fractionating and/or trapping selected molecules with a diffusion barrier or porous membrane. The device includes a source fluid flow channel and a target fluid flow channel. The target fluid flow channel and the source fluid flow channel meet at cross-channel area and are in fluid communication with each other. A porous membrane separates the source fluid flow channel from the target fluid flow channel in the cross-channel area. A field-force/gradient mechanism may be positioned proximate the porous membrane with or without detection/state monitoring devices.12-23-2010
20100028208System and Method for Pseudo-Continuous Measurement of Metabolite Concentrations in a Mammalian Body - A metabolite monitoring system comprising a microdialysis probe including a semi-permeable membrane and a probe flow path passing from an inlet through a sensing volume adjacent to said semi-permeable membrane to an outlet, a fluid delivery device for delivering dialysate to said inlet; and a metabolite monitoring system associated with said outlet for monitoring a concentration of at least one metabolite in said dialysate from said microdialysis probe, wherein said fluid delivery device is configured to deliver a pulsed flow of said dialysate to said inlet.02-04-2010
20100021347Detection Device Based on Surface Plasmon Resonance Effect - The present invention describes a detection device based on the surface plasmon resonance effect, comprising: (1) a rotational microfluidic substrate (01-28-2010
20120308437Detector Module, a Method for Controlling the Detector Module and a Detection System - According to embodiments of the present invention, a detector module is provided. The detector module includes: a chip configured to receive at least one specimen; a first light-emitting diode configured to illuminate the at least one specimen; and a first photodetector configured to detect light emitted from the at least one illuminated specimen. According to further embodiments, a detection system is provided. The detection system includes: a detector module; a control module in electrical communication with the detector module; and a pump module configured to collect a sample and transfer the sample to a chip of the detector module.12-06-2012
20100172802ASSAY DEVICES AND METHODS - A device for determining an assay result may include a test strip, a light source system, a light detection system, and a processor.07-08-2010
20080219892Guided Mode Resonant Filter Biosensor Using a Linear Grating Surface Structure - Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters.09-11-2008
20110171072Apparatus, System and Method for Label-Free Quantitative Detection of Biomolecules - Embodiments of apparatuses, systems, and methods for label-free detection of biomolecules. In one embodiment, a system includes a light source configured to emit broadband Gaussian light. The system may also include an optical fiber coupled to the light source. Additionally, the system may include an optical sensor. The optical sensor may include a fiber-interface surface configured to be coupled to the optical fiber and to receive broadband Gaussian light from the optical fiber. The optical sensor may also include a sensor body coupled to the fiber-interface surface, the sensor body having a refractive index different from a refractive index of the optical fiber, such that at least a portion of light received by the fiber-interface surface is reflected back to the optical fiber during use; and a binder-interface surface coupled to the sensor body, the binder-interface surface configurable to receive a chemical binder layer. Additional embodiments include coherence domain multiplexing and time division multiplexing.07-14-2011
20120045369CHEMICAL ANALYSIS APPARATUS - A chemical analysis apparatus is disclosed as having a liquid flow train assembly for creating a flowing liquid sample stream guided from a sample inlet through the apparatus in a capillary tubing arrangement at low liquid flow rates, the sample containing an analyte to be measured; a reagents dosing and injection device located downstream the sample inlet for introducing a series of chemical reagents into the sample stream; a reactor where the reagents react with the analyte for producing a colored chemical indicator in the fully reacted sample; and a detection for measuring the chemical indicator, located downstream of the reactor means and being configured to receive the fully reacted sample with the colored indicator from the reactor means. The flow train assembly can intermittently let the fully reacted sample pass through the detector when the measurement of the indicator is not made, and to bypass the detector when the measurement of the chemical indicator in the sample is made.02-23-2012
20120301362SYSTEM FOR TESTING A BODILY FLUID SAMPLE - The invention relates to a system for testing a sample of bodily fluid, comprising a carrier band, which carries a plurality of consumable elements, wherein one end of the carrier band is attached to a wind-up device for winding the carrier band, together with used consumable elements, onto a reel for the band transport, and comprising a display for displaying information regarding the supply of yet unused consumable elements of the carrier band. According to the invention, it is provided that information regarding the supply of yet unused consumable elements of the carrier band is obtained from an angle of rotation and from a band transport length by which the carrier band is moved with a rotation of the reel about said angle of rotation.11-29-2012
20120301361PORTABLE CHEMICAL DETECTOR - A portable chemical detector, an embodiment including a material that contains a dye and is permeable to one or more chemicals that activate the dye, a light emitter to transmit light through the material and dye, a light detector to detect the light and a housing in which the material containing the dye, the light emitter, and the light detector are disposed.11-29-2012
20110014087MATERIAL COMPOSITIONS FOR SENSORS FOR DETERMINATION OF CHEMICAL SPECIES AT TRACE CONCENTRATIONS AND METHOD OF USING SENSORS - A method of quantitatively measuring the concentration of a chemical species in a sample solution with a sensor film. A hydrogel sensor film is prepared having a chemical composition comprising an indicator that changes its optical property in the ultra-violet, visible or near-infrared spectral range upon being exposed to the chemical species in the sample solution. The film is exposed to a fixed amount of the sample solution. The concentration of the chemical species in the sample solution is quantified using the average absorbance measured from the sensor film.01-20-2011
20090285720CHANNEL SUBSTRATE - The present application provides a channel substrate has a channel provided therein and includes a plurality of detection portions configured to detect a specimen in the channel using an optical means, an introducing portion configured to introduce the specimen into the channel, and a discharging portion configured to discharge the specimen from the channel. The detection portions have, on at least one of the opposite faces of the channel substrate, detection portion surfaces which have distances different from each other to the channel.11-19-2009
20100092340CLEANING DEVICE, METHOD FOR CLEANING NOZZLE CLOGGING, AND AUTOMATIC ANALYZER - A cleaning device includes a discharge nozzle that discharges cleaning liquid; a suction nozzle that sucks the cleaning liquid or reaction liquid in the cleaning tank or the reaction vessel; a discard vessel connected to the suction nozzle via a pipe to discard the cleaning liquid or the reaction liquid; a detecting unit that detects whether an electrostatic capacity at least between the suction nozzle and an electrode provided in the pipe exceeds a threshold value; a determination unit that determines that the suction nozzle is clogged when a time difference between a time, at which the electrostatic capacity exceeds the threshold value when the suction nozzle is not clogged, and a time, at which the electrostatic capacity exceeds the threshold value at the time of determination, is not less than a predetermined time difference threshold value; and a control unit that stops the discharge nozzle from discharging the cleaning liquid to the reaction vessel when the suction nozzle is clogged.04-15-2010
20120121466METHODS AND SYSTEMS FOR DELIVERY OF FLUIDIC SAMPLES TO SENSOR ARRAYS - Total analysis systems and methods for simultaneously monitoring a suite of biological and/or chemical species in water and/or other process systems are disclosed. The system provides a sample-volume controlled sensor array comprising a fluid delivery device and a plurality of optical sensor elements for determining the presence and total concentrations of multiple analytes in the process system simultaneously. Delivery means are provided to deliver a metered quantity of sample fluid to the sensor array. Image identification algorithms are provided for identifying the analytes based on image intensity, color pattern, positional arrangement, and the like. The methods incorporate multivariate optimization algorithms to analyze multiple sensor responses. This produces analytical results that are typically difficult to obtain without full system or variable compensation. The improved array response may then be utilized to measure, monitor, and control the concentration of analytes in the chemical or biological sample or water system.05-17-2012
20120315190AUTOMATIC ANALYSIS DEVICE - There is provided a data processing method that reduces influences of air bubbles and dirt while maintaining changes in light amounts. Two scattering light photoreceivers are disposed in the forward direction. A photoreceiver 12-13-2012
20120164030CHEMICAL RESERVOIR FOR PORTABLE EXPLOSIVE OR DRUG DETECTION SYSTEM - A chemical test system includes a elastic collapsible tank to maintain constant chemical delivery rate of chemical inside the collapsible tank; and a test swipe including a base and one or more swipe pad positioned on the base to receive chemical for detecting an explosive or drug compound from the collapsible tank. Alternatively, the reservoir can have a solid container that is suitably pressurized to ensure constant chemical fluid flow from the reservoir.06-28-2012
20100239464SUBSTRATE MANUFACTURING METHOD FOR SENSOR APPLICATIONS USING OPTICAL CHARACTERISTICS AND THE SUBSTRATE THEREFROM - A method for manufacturing a substrate of an analytical sensor and the substrate thus prepared are disclosed. The method for manufacturing the substrate of the sensor application according to the present invention is characterized in that it comprises (a) the step of preparing a dispersed solution of nanoparticles, which are stable in a volatile organic solvent due to surface modification of nanoparticles having a pre-designed certain size on the nanometer level with an organic functional group (b) the step of preparing a single layer film of nanoparticles surface-modified with the organic functional group on the interface using said dispersed solution of nanoparticles on the basis of the Langmuir-Blodgett method, and then transferring said single layer film of nanoparticles to the substrate; and (c) the step of coating the substrate to which said single layer film of nanoparticles is transferred, with the metal thin film by means of the vacuum vapor deposition, and then optionally removing nanoparticles to manufacture a nanostructure to be used as the analytical sensor using optical characteristics. According to the method for manufacturing the substrate of the sensor application according to the present invention as above, the nanoparticles can be uniformly fixed on the solid substrate having a great area above 10×10 cm09-23-2010
20100209300ANALYSIS SYSTEM WITH A REMOTE ANALYSING UNIT - A system for analysing a fluid, the system comprising a base station, an analysing unit being remote from the base station, and a substance collecting device being remote both from the base station and from the analysing unit, a first fluid communication link for communicating fluid between the base station and the analysing unit, and a second fluid communication link for communicating fluid between the analysing unit and the substance collecting device, wherein the analysing unit comprises sensing means adapted to provide data representing a content of a substance in the fluid and wherein the base station comprises data processing means being adapted to process the data to provide information regarding the content of the substance in the fluid.08-19-2010
20120177538ANALYZER - The analyzer according to the embodiment comprises an irradiation optical part that irradiates a mixture inside reaction tubes with light from a light source. Moreover, a detection optical part detects light transmitted through the mixture. Moreover, the irradiation optical part comprises a first optical element in which the light source is disposed at the front focal position and that concentrates light from the light source. Moreover, a second optical element guides light transmitted through the first optical element to the reaction tubes. In addition, an incident numerical aperture adjustment member is provided at the rear side of the first optical element and adjusts the numerical aperture when light from the light source is incident on the reaction tubes.07-12-2012
20100272609EXPLOSIVE OR DRUG DETECTION SYSTEM FOR SHIPPING CONTAINERS - A tester to detect the presence of a target substance includes a housing that can be mounted on a shipping container; a chemical reservoir insertable into the housing; a disc or an automated cartridge containing test filter swipes adapted to receive particles or vapor, and a chemical from the chemical reservoir, the test swipe including one or more chemically treated pads; a camera to capture an image from the test swipe; a processor coupled to the camera to process the image to detect the target substance; and a transmitter coupled to the processor to transmit a test result to a remote computer.10-28-2010
20100008826Biosensors featuring confinement of deposited material and intra-well self-referencing - A test device includes one or more sample wells and a biosensor placed in the well. The biosensor includes structural features promoting confinement of a deposited material, e.g., surface chemistry material, to stay within a specified predetermined area in the well. The biosensor is also constructed with two or more distinct spatial regions exhibiting different resonance values (“peak wavelength values” or PWV). One of the distinct spatial regions encompasses the specified predetermined area where the material is deposited and exhibits resonance at PWV01-14-2010
20120230874TEST SENSOR AND METHOD FOR MANUFACTURING THE SAME - According to one embodiment of the present invention, an optical-based test sensor for use in the determination of an analyte in a liquid sample is disclosed. The test sensor includes a base, a polymer carrier, and a test membrane. The base has a capillary channel formed in a surface of the base that is adapted to move a liquid sample from an inlet to a reaction area formed in the base. The polymer carrier has a lower surface adhered to the surface of the base and is disposed over at least a portion of the capillary channel. The test membrane, which contains a reagent, is adhered to the lower surface of the polymer carrier and extends from the polymer carrier into the reaction area.09-13-2012
20120321519TEST DEVICE AND METHOD - A connection assembly for a test device comprises a carriage for receiving at least a portion of a test device and a receptacle for co-operation with the carriage. The carriage is longitudinally movable with respect to the receptacle and is latchable to the receptacle at a predetermined position.12-20-2012
20120288409ANALYSIS DEVICE - An analysis device using scattering light is provided capable of, when a foreign substance such as a bubble is mixed in a measurement target or is attached in a reaction container, reducing the influence by the foreign substance while improving the S/N ratio characteristics. Two or more detectors are disposed on a plane orthogonal to an optical axis of light applied to the measurement target and on a circumference around the optical axis. A change in outputs from the detectors is observed, and a detector influenced by noise due to a foreign substance such as a bubble is specified for rejection, and outputs from the detectors are averaged.11-15-2012
20080233009Fluidic Volume Dispense Verification Tool - Disclosed herein is a device for measuring fluid dispense volumes including one or more wells adapted to receive a fluid; a tube having an internal passageway fluidly coupled to the one or more wells, wherein fluid in the wells passes into the internal passageway via capillary action to form a fluid column having a meniscus spaced from the wells; and a scale coupled to the tube, the scale calibrated to provide an indication of the volume of the fluid based upon the location of the meniscus in the fluid passageway.09-25-2008
20080233008Chemical sensor with an indicator dye - A chemical sensor based on an indicator dye wherein a light transmissive element containing the indicator dye is made of a hygroscopic polymer. The polymer may be, for example, a polyimide or PMMA or other polymer. In an alternative embodiment the light transmissive element is doped with metal nanocolloidal particles. One embodiment may include a reference photodiode and differential amplifier to compensate for the fluctuations of the intensity of the light source. The light source may be pulse modulated. The sensor may include calibration means comprising a reference sample of the chemical to be detected and a precision delivery means. A method of fabricating the polymer and metal nanocolloid is disclosed wherein the nanocolloid is produced by generating a pulsed laser plasma in a suspension of metal particles and an organic solvent and adding the resulting solvent colloid to a solution containing the polymer.09-25-2008
20110274585MIXING CARTRIDGE AND SAMPLE TESTING DEVICE - According to one embodiment, a mixing cartridge mixes a first solution containing a sample with a second solution corresponding to a measurement item of the sample to be tested. The mixing cartridge includes a member, a first liquid supplying unit, a second liquid supplying unit, and a separating unit. A channel is formed in the member. A solution containing at least one of the first solution and the second solution passes through the channel. The first liquid supplying unit supplies the first solution to the channel. The second liquid supplying unit supplies the second solution to the channel. The separating unit communicates with the channel and separates a portion of the solution from the solution passing through the channel by capillary action.11-10-2011
20080219891PORTABLE SENSOR ARRAY SYSTEM - A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.09-11-2008
20080213133FLOW ANALYSIS APPARATUS AND METHOD - A flow analysis apparatus is disclosed. The flow analysis apparatus has at least one wicking channel fluidically coupled to an absorbent pump. A wicking valve is fluidically coupled to the wicking channel to provide a fluidic connection to the sample source where opening the wicking valve allows the absorbent pump to cause liquid to flow down the wicking channel toward the absorbent pump. Other similar wicking valves can be added to provide functions such as calibration and reagent addition. A detection unit allows for analysis of the liquid as it flows down the wicking channel.09-04-2008
20100284862CLEANING EQUIPMENT AND ANALYZER - An analyzer (11-11-2010
20100290953FLUID CONTENT MONITOR - A fluid content monitor including a cuvette, a colorimeter adapted to generate a signal indicative of contents of a fluid sample contained in the cuvette, a container for holding a reagent, and a pump assembly for delivering reagent from the container to the cuvette. The pump assembly includes a tube extending from the container to the cuvette, check valves preventing reverse flow in the tube, and a hammer driven by a solenoid for repetitively compressing the tube to pump reagent to the cuvette. The cuvette can be removed for cleaning and replacement.11-18-2010
20120282141AUTOMATIC ANALYZER - An automatic analyzer and an automatic analyzing system to identify samples and reagents used in the analyzer and members used in measurement of at least two objects in common: system reagents or buffer solution; sensor parts; probes; nozzles; chips; dispensing cups; tubes; ISE electrodes; detectors; deionized water; and waste, and to unify management of identification information thereof and a measurement result.11-08-2012
20120282140Biochip With A Piezoelectric Element For Ultrasonic Standing Wave Generation - The present invention relates to a biochip with a piezoelectric element for ultrasonic standing wave generation. The biochip comprises an upper module, a lower module, and a chemical sensor. The piezoelectric element is integrated within the upper module of the biochip. The piezoelectric element can generate ultrasonic standing waves (USW) in the reaction chamber of the biochip by manipulating the operation frequency so the particles being detected can effectively move toward the QCM sensing surface. Hence, the biochip significantly increases the sensitivity and reduces the time required to reach equilibrium when undergoing USW excitation. The biochip of the present invention can be broadly applied to the bio-detection in medical and pharmaceutical fields.11-08-2012
20130183199METHOD AND DEVICE FOR ANALYSIS AND READING - An analyzing and reading device and an analyzing and reading method, for reading and analyzing a test strip for assay detection are disclosed. The test strip has a detection zone and a blank zone, the device includes a photoelectric detection circuit and a processor, wherein the photoelectric detection circuit includes at least two light sources which locate corresponding to the positions of the detection zone and the blank zone of the test strip and are able to emit lights corresponding to the detection zone and blank zone of the test strip, and at least one optical detectors which receive reflected lights from the above two zones; wherein lights emitted by the at least two light sources irradiate the detection zone and blank zone of the strip and are reflected therefrom, and then are received by the optical detector, which in turn feedback the detection information to the processor; the processor making analysis and decision based on the detection information received. The analyzing and reading device and method according to the present invention have high accuracy and less interference when reading.07-18-2013
20110293479CARTRIDGE FOR MEASURING BIOLOGICAL SAMPLE COMPONENT AND APPARATUS FOR MEASURING BIOLOGICAL SAMPLE COMPONENT - A cartridge for measuring a biological sample component and an apparatus for measuring a biological sample component are provided. The cartridge for measuring a biological sample component includes: an upper cartridge having a first chamber storing a biological sample, a first channel connected to the first chamber and delivering air pressure to the first chamber, and a third channel transferring the biological sample; and a lower cartridge having a third chamber storing a first reagent, a fifth chamber storing a second reagent, a fifth channel connecting the third and fifth chambers and transferring the second reagent to the third chamber, an eleventh channel delivering the biological sample delivered through the third channel to the third chamber, and a thirteenth channel delivering air pressure to the fifth chamber, wherein when the upper and lower cartridges are bounded by an external force, the third channel and the eleventh channel are connected.12-01-2011
20110311397REACTION CONTAINER HOLDER AND ANALYZER - A reaction container holder capable of inhibiting the lowering of the transfer efficiency of heat transferred from a rotating member to a bottom surface of a reaction container, and an analyzer comprising the reaction container holder, are provided. In a reaction container holder comprising: a retaining member unit comprising a plurality of container retaining sections for retaining reaction containers, which house a reaction liquid containing a reagent and a specimen; and a circular rotating member for detachably fixing the unit from above and rotating, the holder keeping the container at a constant temperature by transferring heat from a heat source through the rotating member to the container, the rotating member comprises a level difference section, an upper surface of which is positioned below a bottom surface of the container retained by the unit and above a bottom part of the section, when the retaining member unit is fixed.12-22-2011
20120020840DETECTION SYSTEM - A system for detecting small quantities of agent such as DNA in a larger volume of substance is disclosed. The system includes a radiation emitter arranged so as to emit radiation on to a quantity of substance containing the agent. The incident radiation excites the agent causing it to emit radiation detectable by suitable detection means. The incident and emitted radiation are directed by a light guide that also acts so as to contain the substance being monitored.01-26-2012
20120020839ANALYTICAL TEST ELEMENT AND PROCESS FOR ITS PRODUCTION - An analytical test element is provided having a surface comprising a chemical detection layer on which a spreading net is disposed, the spreading net being configured to provide for the planar distribution of a liquid sample on the detection layer. The spreading net generally comprises a filament structure coated with a metallic layer that is oxidized at least on one or more surface portions thereof facing the detection layer.01-26-2012
20130195722LOW VOLUME ASSAY APPARATUS - Apparatus (08-01-2013

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