Class / Patent application number | Description | Number of patent applications / Date published |
359389000 | With illumination and viewing paths coaxial at the image field | 30 |
20080239476 | Illuminating module and surgical microscope incorporating said illuminating module - An illuminating module ( | 10-02-2008 |
20080291533 | ILLUMINATOR FOR A 3-D OPTICAL MICROSCOPE - A compact and low cost microscope illuminator capable of generating 3-D optical images includes a first light source and a second light source. The two light sources lead two optical paths: one to illuminate a sample and another to project a pattern onto the focal plane of a microscope objective lens. The two light sources are controlled by a processor and can be turned on and off rapidly. A 3-D optical microscope equipped with said microscope illuminator and a method of creating a 3-D image on said 3-D optical microscope are also described. | 11-27-2008 |
20080297891 | Microscope and method of providing image data using the same - A microscope includes optics configured to direct beams onto an object including a reflective material, a detector configured to receive a field spectrum formed by beams reflected by the object, and a calculator configured to reconstruct an image of the object from the field spectrum detected by the detector. | 12-04-2008 |
20080297892 | Surgical microscope having an illuminating arrangement - A surgical microscope ( | 12-04-2008 |
20090002813 | MICROSCOPE WITH CENTERED ILLUMINATION - A microscope comprising a main objective having a variable focal length and comprising an illuminating unit including a light source and an illuminating optical system for generating an illuminating beam path directed onto the object plane and extending outside the main objective. A unit is provided for centering the illumination dependent on a variation of the focal length of the main objective. The illuminating optical system is mounted at least in part in a laterally shiftable manner for centering the illumination. | 01-01-2009 |
20090002814 | MICROSCOPE WITH CENTERED ILLUMINATION - A microscope comprising a main objective including a lens assembly movable in the direction of the optical axis of the main objective for focal length variation and comprising an illuminating unit with an illumination deflector element for generating an illuminating beam path directed onto an object plane and extending outside the main objective. The position of the illumination deflector element is adjustable dependent on a focal length variation of the main objective for centering the illumination. The illumination deflector element is movable in a direction parallel to the optical axis of the main objective and is coupled to the movable lens assembly of the main objective. | 01-01-2009 |
20090021827 | MICROSCOPE WITH CENTERED ILLUMINATION - A microscope comprising a main objective having a lens assembly movable in the direction of the optical axis of the main objective for focal length change and comprising an illuminating unit with illumination deflector elements for deflecting an illuminating beam path for generating an illuminating beam path directed onto an object plane. The position of the illumination deflector elements is adjustable dependent on a focal length change of the main objective for centering the illumination, and the illumination deflector elements are designed as at least partly integrated into the movable lens assembly of the main objective. For this purpose, in particular a part of the lens surface of the movable lens assembly can be made reflective. | 01-22-2009 |
20090034064 | Automatic microscope provided with an illumination field arranged in the aperture diaphragm plane of a condenser - In an automatic microscope, there is the task to satisfy the demand for an economical, compact structure, especially a miniaturization as an essential aspect. The automatic microscope contains an optical system having the following: an illumination field ( | 02-05-2009 |
20090040603 | Objective lens - In order to provide an objective lens which can reduce the generation of flare light, an objective lens including a front-group lens, a rear-group lens arranged on an optic axis of the front-group lens with the front-group lens interposed between an object plane and the rear-group lens, and a semitransparent mirror arranged between the front-group lens and the rear-group lens for reflecting illumination into the front-group lens, transmitting reflected light from the object plane and entering the transmitted light into the rear-group lens is provided. The front-group lens is a single lens or a cemented lens formed by sticking two lenses together. | 02-12-2009 |
20090059363 | MICROSCOPE SYSTEM - A microscope system for imaging an object which can be arranged in an object plane of the microscope system, which includes an imaging system, a displacement device and a controller is described. The imaging system may provide at least one optical imaging path for imaging an imaging field of the object plane. The displacement device may be adapted to translatory displace the imaging field of the imaging system in the object plane. The controller is adapted to determine a desired displacement of the imaging field in the object plane and to correspondingly control the displacement device. | 03-05-2009 |
20090109527 | SCANNING LASER MICROSCOPE - A scanning laser microscope includes a laser light source; an acousto-optic deflector having a crystal, being arranged in an optical path of a laser beam emitted from the laser light source and capable of changing a traveling direction of the laser beam when frequencies of acoustic waves applied to the crystal are changed; a frequency control unit configured to simultaneously apply acoustic waves having a plurality of frequencies to the crystal of the acousto-optic deflector; an objective lens configured to converge the laser beam emitted from the laser light source to form a beam spot on a specimen; and an optical scanning device configured to two-dimensionally scan the scanning spot by deflecting the laser beam in two directions perpendicular to each other. The acousto-optic deflector, the optical scanning device, and a pupil of the objective lens are arranged at positions optically conjugate with each other. | 04-30-2009 |
20100053745 | VIDEO ADAPTER FOR A MICROSCOPE CAMERA - A video adapter for a microscope is described, comprising a first connection for connecting the microscope; a second connection for connecting a camera; and at least one optical component for performing at least one of exposure setting, focus setting, magnification setting and deflection of at least one part of an observation beam path of the microscope into an image plane of the camera. The at least one optical component has an SLM optical unit. Further, a system is described comprising the aforementioned video adapter, a microscope, and a camera. | 03-04-2010 |
20100079858 | CONFOCAL SCANNING MICROSCOPE - A confocal scanning microscope including: an objective system (second objective lens | 04-01-2010 |
20100172021 | LASER MICROSCOPE - A laser microscope comprises a laser light source which emits a laser light, an objective lens which condenses the laser light from the laser light source onto a specimen, an optical scanning unit which two-dimensionally scans the laser light on the specimen, a beamsplitter which separates light emitted from a condensed position on the specimen of the laser light from the laser light source, the beamsplitter being disposed between the objective lens and the optical scanning unit, an optical fiber in which an incident end is disposed at an optical path separated by the beamsplitter, and to which the light from the specimen is made to be incident, and a spectroscope which is disposed at an exit end of the optical fiber, and to which light from the specimen which is emitted from the exit end is made to be incident. | 07-08-2010 |
20100182683 | LASER EXCITATION FLUORESCENT MICROSCOPE - The present application has a proposition to provide a highly efficient laser excitation fluorescent microscope. Accordingly, a laser excitation fluorescent microscope of the present application includes a laser light source part radiating at least two types of excitation lights having different wavelengths; a light collecting part collecting the two types of excitation lights on a sample; a high-functional dichroic mirror, disposed between the laser light source part and the light collecting part, reflecting the two types of excitation lights to make the excitation lights incident on the light collecting part, and transmitting two types of fluorescence generated at the sample; and a detecting part detecting light transmitted through the high-functional dichroic mirror, in which an incident angle θ of the excitation lights and the fluorescence to the high-functional dichroic mirror satisfies a formula of 0°<θ<45°. | 07-22-2010 |
20100315708 | TOTAL INTERNAL REFLECTION INTERFEROMETER WITH LATERALLY STRUCTURED ILLUMINATION - A total internal reflection microscope for epi-fluorescence illumination observations includes an objective through which an object to be observed is illuminated by an excitation illumination light at an angle to an observation axis of the microscope. The angle is adjustable to be within the range suitable for a total internal reflection observation. The microscope also has a source of collimated excitation light. An interferometer is arranged in the optical path of the collimated excitation light and is configured to produce an interference pattern. A focusing lens system focuses the interference pattern produced by the interferometer into the back focal plane of the objective. The objective and the focusing lens system image the interference pattern produced by the interferometer into the conjugated image plane of the objective, thereby producing excitation illumination light that modulated spatially in intensity in a plane orthogonal to the observation axis of the microscope. | 12-16-2010 |
20110090562 | AUTOFOCUS APPARATUS - An autofocus apparatus includes, in one embodiment, a light source; a splitter; a fiber optic circulator; an optical collimator; a balance detector; and a microprocessor. The fiber optic circulator couples one of the split light signals at a first port, to the optical collimator at a second port, and to the balance detector at the third port. The optical collimator directs the light beam from the fiber optic circulator onto a sample through a Dichroic mirror and a microscope objective. The balance detector uses another one of the split light signals as an input, and converts a light signal, reflected off of a substrate the sample is placed on, into an analog voltage signal. The microprocessor processes the output of the balance detector and position feedbacks from an adjustable microscopy stage to generate a command for moving the position of the adjustable microscopy stage to achieve a desired focus. | 04-21-2011 |
20110164315 | Surgical Microscope having an Illuminating Arrangement - A surgical microscope ( | 07-07-2011 |
20110242649 | Wavefront measurement method, wavefront measurement apparatus, and microscope - A wavefront is measured with superior precision even if the density of scatterers in the vicinity of a focal plane is low. Provided is a wavefront measurement method including a contrast measuring step of measuring the contrast of an interference pattern corresponding to each part of a specimen containing a scatterer, generated by interfering reference light and return light from a focal plane in the specimen; a region extracting step of extracting a high-contrast region in which the contrast measured in the contrast measuring step is greater than or equal to a prescribed threshold; and a wavefront calculating step of converting an interference pattern corresponding to the high-contrast region to wavefront data, for the high-contrast region extracted in the region extracting step. | 10-06-2011 |
20120038980 | CONFOCAL MICROSCOPE APPARATUS - A confocal microscope apparatus comprises a first optical scanning system which obtains a scan image of a sample using a laser beam from a first laser light source, a second optical scanning system which scans specific regions of a sample with a laser beam from a second laser light source that is different from the first laser light source, thereby causing a particular phenomenon, and a beam diameter varying mechanism which can change the beam diameter of the laser beam of at least one of the first optical scanning system and the second optical scanning system. With this configuration, the apparatus further comprises an excitation light intensity distribution calculator which calculates and stores the excitation light intensity distribution along a depth direction on the sample surface from the beam diameter of the laser beam output from the beam diameter varying mechanism. | 02-16-2012 |
20120147460 | SYSTEM FOR WAVEFRONT ANALYSIS AND OPTICAL SYSTEM HAVING A MICROSCOPE AND A SYSTEM FOR WAVEFRONT ANALYSIS - An optical system, comprising a microscope housing having a coupling opening for a detachable coupling of an objective lens of the optical system such that the objective lens is arranged in a microscope beam path of the optical system for imaging an object region of the objective lens. The optical system further comprises an assembly. The assembly comprises an assembly housing having a coupling element for the detachable coupling of the coupling element and the coupling opening of the microscope housing; a wavefront analysis system, which provides a wavefront beam path; and a beam splitter, which is arranged in the wavefront beam path. The objective lens, the beam splitter and the wavefront analysis system are arranged such that during the coupling of the coupling opening and the coupling element, the objective lens is arranged in the microscope beam path and the object region is arranged in the wavefront beam path. | 06-14-2012 |
20130293952 | AUTOFOCUS APPARATUS - An autofocus apparatus includes, in one embodiment, a light source; a splitter; a fiber optic circulator; an optical collimator; a balance detector; and a microprocessor. The fiber optic circulator couples one of the split light signals at a first port, to the optical collimator at a second port, and to the balance detector at the third port. The optical collimator directs the light beam from the fiber optic circulator onto a sample through a Dichroic mirror and a microscope objective. The balance detector uses another one of the split light signals as an input, and converts a light signal, reflected off of a substrate the sample is placed on, into an analog voltage signal. The microprocessor processes the output of the balance detector and position feedbacks from an adjustable microscopy stage to generate a command for moving the position of the adjustable microscopy stage to achieve a desired focus. | 11-07-2013 |
20130335819 | SYSTEMS AND METHODS FOR ILLUMINATION PHASE CONTROL IN FLUORESCENCE MICROSCOPY - Illumination phase controls that provide precise and fast phase control of structured illumination patterns used in structure illumination microscopy are described. A coherent light source is used to generate a beam of coherent light that is split into at least three coherent beams of light. In one aspect, an illumination phase control is composed of at least one pair of rotatable windows to apply at least one phase shift to at least one of the beams. An objective lens is to receive the beams and focus the at least three beams to form an interference pattern. The phase control can be used to change the position of the interference pattern by changing the at least one phase shift applied to the at least one beam. | 12-19-2013 |
20140268320 | IMAGE PROCESSING APPARATUS, MICROSCOPE SYSTEM, IMAGE PROCESSING METHOD, AND COMPUTER-READABLE RECORDING MEDIUM - An image processing apparatus includes an image input unit configured to input a plurality of images acquired by imaging a specimen stained with non-fluorescent dye at a plurality of wavelength bands that are different from one another and a characteristic amount calculation unit configured to calculate a characteristic amount representing auto-fluorescence emitted by the specimen based on the plurality of images. | 09-18-2014 |
20150009559 | AUTOFOCUS APPARATUS - An autofocus apparatus includes a light source; an optical coupler having a first port, second port and a third port; wherein the optic coupler couples to the light source at the first port; an optical collimator for directing a light output from the second port of the optical coupler onto a sample through a Dichroic mirror and a microscope objective, wherein the sample is placed on a substrate supported by an adjustable microscopy stage; a scanning device for focusing the light at a plurality of focal points along an axis; a photodiode detector for converting a reflected light signal into an intensity signal; a memory device for storing a signal template; and a microprocessor for detecting a peak in the intensity signal by cross-correlating the intensity signal with the signal template; wherein the microprocessor generates a command for moving the position of the adjustable microscopy stage along the axis. | 01-08-2015 |
20150131148 | SPINNING DISK CONFOCAL USING PAIRED MICROLENS DISKS - A spinning-disk confocal unit uses a pair of microlens arrays to create an infinity space directly after the pinhole array. This at least allows flexibility in the confocal unit design and also allows incorporation of superresolution. | 05-14-2015 |
20150301322 | Apparatus for Structured Illumination of a Specimen - An apparatus for structured illumination of a specimen comprises an illumination device for generating illumination beams. The illumination beams are incident on a mask device. Openings provided in the mask device serve for generating a mask image. The mask image is imaged within the specimen with the aid of an objective. Detection beams generated by the specimen are captured by a detection device. For increasing the intensity of the observation beams entering the specimen, those beams which do not pass through the openings, are collected with the aid of a beam collector and guided back to the mask device. | 10-22-2015 |
20150346098 | Optical Filter System and Fluorescence Observation System - An optical filter system for florescence observation comprises an illumination light filter (I) and an observation light filter (O). The observation light filter has plural transmitting regions (D | 12-03-2015 |
20150355446 | METHOD FOR THE MICROSCOPE IMAGING OF SAMPLES ADHERING TO BOTTOMS OF FLUID FILLED WELLS OF A MICROTITER PLATE - A method for microscope imaging of a sample, wherein a sample well is filled with liquid with the sample adhered to the bottom, illuminating and imaging the sample well from the underside and capturing at least one sample image thereof, wherein any inhomogeneity of the illumination is equalized by providing a test well with the same structure filled with liquid but no sample, making a reference measurement of the test well by illuminating the test well, imaging the illuminated test well from the underside and capturing a reference image which covers the entire bottom, analyzing the reference image to determine a brightness correction specification based on brightness fluctuation, and using the brightness correction specification to correct the sample image, including determining a position of at least a part of the sample image and using a value of the brightness correction specification assigned to the position. | 12-10-2015 |
20170235116 | LIGHTING ARRANGEMENT | 08-17-2017 |